TB-Profiler result

Run: ERR126600

Summary

Run ID: ERR126600

Sample name:

Date: 2024-03-27T02:57:49.399475

Number of reads: 2625824

Percentage reads mapped: 23.53

Median coverage: 49.0

Strain: La3;M.canetti;lineage2.1;lineage4.9;lineage6.3

Spoligotype:

Drug-resistance: MDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.2 Indo-Oceanic RD239 0.08
lineage4.1.4 Euro-American None 0.05
lineage6.3 West-Africa 2 RD702 0.1
lineage4.3.2.1 Euro-American (LAM) RD761 0.16
lineage3.1.2.2 East-African-Indian RD750 0.22
lineage6.1.3 West-Africa 2 RD702 0.21
lineage2.1 East-Asian (non-Beijing) None 0.31
lineage1.1.1 Indo-Oceanic RD239 0.16
lineage6.2.3 West-Africa 2 RD702 0.21
lineage4.9 Euro-American (H37Rv-like) None 0.71
La1.7.1 M.bovis None 0.1
La3 M.orygis None 0.46
M.canetti M.canetti None 0.37
lineage4.6.2.1 Euro-American RD726 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.496_498delGTTinsAC Assoc w R High-level resistance
c.300_301delGC Assoc w R High-level resistance
c.296_297insTG Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.-2_1delGCGinsCGGA Assoc w R
c.4_6delGCAinsTT Assoc w R
kanamycin
cycloserine
ethionamide ethA c.478_480delCCGinsAC Assoc w R
c.460_462delTCGinsGC Assoc w R
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.604_606delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1039_1041delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1948_1950delCGCinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.772_774delACGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 0.99 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303534 c.604_606delTCGinsGC frameshift_variant&missense_variant 0.97 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303969 c.1039_1041delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304878 c.1948_1950delCGCinsAG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.99 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance Mutation from literature
tlyA 1917938 c.-2_1delGCGinsCGGA frameshift_variant&synonymous_variant 1.0 capreomycin Assoc w R
tlyA 1917943 c.4_6delGCAinsTT frameshift_variant&missense_variant 1.0 capreomycin Assoc w R
katG 2155108 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.96 isoniazid Assoc w R High-level resistance
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 0.99 isoniazid Assoc w R High-level resistance
katG 2155810 c.300_301delGC frameshift_variant 1.0 isoniazid Assoc w R High-level resistance
katG 2155815 c.296_297insTG frameshift_variant 0.97 isoniazid Assoc w R High-level resistance
fbiA 3641314 c.772_774delACGinsGC frameshift_variant&missense_variant 0.94 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.99 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 1.0 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 1.0 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 1.0 ethambutol Mutation from literature
ethA 4326994 c.478_480delCCGinsAC frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4327012 c.460_462delTCGinsGC frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 187 c.187_189delTTAinsCG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 192 c.192C>G synonymous_variant 1.0 isoniazid
dnaA 204 c.204C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 207 c.207T>C synonymous_variant 1.0 isoniazid
dnaA 210 c.210C>G synonymous_variant 1.0 isoniazid
dnaA 213 c.213A>G synonymous_variant 1.0 isoniazid
dnaA 219 c.219A>G synonymous_variant 1.0 isoniazid
dnaA 225 c.225G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 228 c.228C>G synonymous_variant 1.0 isoniazid
dnaA 231 c.231T>C synonymous_variant 1.0 isoniazid
dnaA 237 c.237G>C synonymous_variant 1.0 isoniazid
dnaA 246 c.246T>C synonymous_variant 1.0 isoniazid
dnaA 255 c.255T>G synonymous_variant 1.0 isoniazid
dnaA 498 c.498C>G synonymous_variant 1.0 isoniazid
dnaA 504 c.504T>C synonymous_variant 1.0 isoniazid
dnaA 510 c.510T>C synonymous_variant 1.0 isoniazid
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>G synonymous_variant 1.0 isoniazid
dnaA 540 c.540C>G synonymous_variant 1.0 isoniazid
dnaA 543 c.543C>G synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 576 c.576G>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 591 c.591C>G synonymous_variant 1.0 isoniazid
dnaA 600 c.600T>C synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 610 c.610C>T synonymous_variant 1.0 isoniazid
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 660 c.660G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 1.0 isoniazid
dnaA 669 c.669C>T synonymous_variant 1.0 isoniazid
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 690 c.690G>C synonymous_variant 1.0 isoniazid
dnaA 693 c.693A>C synonymous_variant 1.0 isoniazid
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>C synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 786 c.786C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 933 c.933C>G synonymous_variant 1.0 isoniazid
dnaA 942 c.942C>G synonymous_variant 1.0 isoniazid
dnaA 945 c.945G>A synonymous_variant 1.0 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.98 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.98 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.98 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.97 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.96 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1002 c.1002G>A synonymous_variant 0.96 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 0.96 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.97 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.97 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.98 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.97 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.97 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 1.0 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 1.0 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.98 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.99 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.99 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.99 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>C synonymous_variant 0.99 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.98 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.98 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.98 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.97 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.96 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.99 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.99 isoniazid
dnaA 1197 c.1197T>A synonymous_variant 0.99 isoniazid
dnaA 1204 c.1204C>T synonymous_variant 0.99 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.99 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.99 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.99 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.99 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.99 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.99 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.99 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.99 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.99 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.99 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 0.98 isoniazid
dnaA 1332 c.1332A>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1335 c.1335G>A synonymous_variant 0.98 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 0.98 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.97 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1365 c.1365C>G synonymous_variant 0.98 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.98 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.99 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.98 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.98 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.97 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.97 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.97 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.97 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.97 isoniazid
dnaA 1419 c.1419C>G synonymous_variant 0.97 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.98 isoniazid
dnaA 1461 c.1461C>A synonymous_variant 0.95 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.94 isoniazid
dnaA 1470 c.1470C>G synonymous_variant 0.93 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 1485 c.1485A>G synonymous_variant 0.94 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.94 isoniazid
dnaA 1503 c.1503C>T synonymous_variant 0.96 isoniazid
gyrB 5772 p.Ala178Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 5774 c.535_537delGTTinsAC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5782 c.543A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5788 c.549G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5791 c.552A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5806 c.567C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5809 c.570C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5815 c.576C>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5824 c.585A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5827 c.588G>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5848 c.609G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5863 c.624G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 5882 c.643_645delCAAinsAC frameshift_variant&missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin
gyrB 5887 p.Asp216Glu missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6169 c.930C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6217 c.978G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6299 c.1060C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6325 c.-977C>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6440 c.1201_1203delACCinsGA frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6542 c.1303_1305delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6565 c.-737G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6577 c.-725T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6602 c.-700C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6790 c.-512C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6824 c.1585C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6931 c.-371A>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6937 c.1698G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6941 c.-361C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7018 c.-284G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7124 c.1885_1887delTCGinsAC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7237 c.-65C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7243 c.-59G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7258 c.-44G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7344 p.Ile15Val missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7355 c.54T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7838 c.537C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7862 c.561C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7884 c.583_585delCGTinsGC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 7942 p.Glu214Ala missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7955 c.654G>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7958 c.657C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7970 c.669T>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7976 c.675C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7992 p.Ala231Ser missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7997 c.696A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8009 c.708A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8010 c.709_711delTCCinsAG frameshift_variant&synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8054 c.753T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8498 c.1197C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Gln missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8562 c.1261C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8576 c.1275C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8735 c.1434C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 c.1495_1497delATCinsGG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8951 c.1650G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.99 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9134 c.1833C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.83 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9152 c.1851C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9281 c.1980C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9413 c.2112G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9575 c.2274G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9578 c.2277C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9597 c.2296T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9605 c.2304C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9611 p.Asp770Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9647 c.2346C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9665 c.2364A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9666 p.Arg789Gly missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9674 c.2373T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9704 c.2403T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9708 c.2407T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9722 c.2421C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9738 c.2437T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
Rv0010c 13879 c.-321T>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 1.0 isoniazid
fgd1 490549 c.-234T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490555 c.-228G>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490559 c.-224G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490573 c.-210T>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490577 c.-206T>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490581 c.-202_-201delACinsGT upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490597 c.-186G>C upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490598 c.-185G>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490601 c.-182G>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490604 c.-179A>G upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490613 c.-170A>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490617 c.-166_-165delTTinsGC upstream_gene_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490627 c.-156T>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490634 c.-149A>T upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490827 c.45C>T synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490833 c.51G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490842 c.60C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491031 c.249C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491038 p.Ile86Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Gly missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491137 p.Glu119Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.99 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491388 c.606C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491453 p.Gly224Asp missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 c.720G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491532 c.750G>T synonymous_variant 0.99 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491542 c.760T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491583 c.801G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574535 c.-813C>G upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574541 c.-807T>C upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574550 c.-798C>G upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574553 c.-795T>C upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574559 c.-789T>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574565 c.-783T>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574574 c.-774A>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574576 c.-772_-771delCCinsAG upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574586 c.-762G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574589 c.-759T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574592 c.-756C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574595 c.-753A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574616 c.-732G>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574625 c.-723C>G upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574655 c.-693C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574664 c.-684G>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574671 c.-677_-675delGCAinsCTG upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.97 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 574700 c.-648C>G upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 574718 c.-630A>C upstream_gene_variant 0.95 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575018 c.-330C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575030 c.-318T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575034 c.-314_-312delTTAinsAG upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575042 c.-306T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575051 c.-297A>G upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575060 c.-288G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575063 c.-285T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575066 c.-282C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575072 c.-276G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575081 c.-267A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575084 c.-264T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575117 c.-231T>C upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 575118 c.-230A>G upstream_gene_variant 0.97 ethionamide
isoniazid Uncertain significance
mshA 575123 c.-225A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575124 c.-224_-222delGGGinsCC upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575137 c.-211C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575144 c.-204T>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575153 c.-195C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575154 c.-194_-192delGTGinsCC upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575161 c.-187_-186delTTinsCC upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575527 c.180G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575542 c.195C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.98 ethionamide
isoniazid
mshA 575569 c.222A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.98 ethionamide
isoniazid
mshA 575575 c.228G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575587 c.240C>A synonymous_variant 0.99 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575623 c.276C>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 575629 c.282A>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575648 p.Val101Gln missense_variant 0.98 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.97 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.99 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575902 c.555C>T synonymous_variant 0.94 ethionamide
isoniazid Not assoc w R - Interim
mshA 576154 c.807C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576163 c.816A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576184 c.837A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576193 c.846T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576197 c.850C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 576205 c.858G>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 576211 c.864C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576214 c.867G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 576215 c.868T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576233 c.886_888delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576247 c.900A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576258 p.Ser304Thr missense_variant 1.0 ethionamide
isoniazid
ccsA 619502 c.-389_-388delAAinsCG upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619507 c.-384A>G upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>G upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGCG upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>G upstream_gene_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 619558 c.-333G>C upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619564 c.-327C>G upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619627 c.-264C>G upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619633 c.-258G>A upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619648 c.-243C>G upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>C upstream_gene_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCC upstream_gene_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619912 p.Val8Ile missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619916 p.Gly9Glu missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619923 c.33C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619947 c.57C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619953 c.63C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 619969 p.Val27Ile missense_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R
kanamycin Uncertain significance
ccsA 619989 c.99G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619996 p.Phe36Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620153 p.Ile88Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620157 c.267G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620169 c.279G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 c.283_285delGTCinsCG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620265 c.375C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620275 c.385C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620461 p.Val191Ile missense_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620482 p.Val198Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620490 c.600A>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620495 p.Arg202Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620569 c.679_681delGGAinsCC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620589 c.699G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620809 c.919C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620829 c.939G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620838 c.948C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620847 c.957G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656031 c.1440A>G synonymous_variant 1.0 ethionamide
Rv0565c 656037 c.1434G>A synonymous_variant 1.0 ethionamide
Rv0565c 656052 c.1419A>C synonymous_variant 1.0 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 0.94 ethionamide Uncertain significance
Rv0565c 656085 c.1386A>G synonymous_variant 0.94 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 0.94 ethionamide
Rv0565c 656091 c.1380T>C synonymous_variant 0.94 ethionamide
Rv0565c 656097 c.1374G>C synonymous_variant 0.94 ethionamide
Rv0565c 656112 c.1359C>G synonymous_variant 0.94 ethionamide
Rv0565c 656118 c.1353C>G synonymous_variant 0.91 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.97 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.97 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.97 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 1.0 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 1.0 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 1.0 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656526 p.Glu315Asp missense_variant 1.0 ethionamide
Rv0565c 656535 c.936C>G synonymous_variant 1.0 ethionamide
Rv0565c 656539 p.Ser311Ala missense_variant 1.0 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 1.0 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 1.0 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 1.0 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 1.0 ethionamide
Rv0565c 656604 c.867G>C synonymous_variant 1.0 ethionamide
Rv0565c 656611 p.Thr287Lys missense_variant 1.0 ethionamide
Rv0565c 656853 c.618A>G synonymous_variant 1.0 ethionamide
Rv0565c 656859 p.Glu204Ala missense_variant 1.0 ethionamide
Rv0565c 656865 c.606G>C synonymous_variant 1.0 ethionamide
Rv0565c 656872 p.Thr200Ser missense_variant 1.0 ethionamide
Rv0565c 656876 c.595C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656880 c.591C>G synonymous_variant 1.0 ethionamide
Rv0565c 656883 c.586_588delATCinsCG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656889 c.582A>G synonymous_variant 1.0 ethionamide
Rv0565c 656901 c.570C>A synonymous_variant 1.0 ethionamide
Rv0565c 656922 c.547_549delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657138 c.331_333delGCAinsTG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657144 c.327T>G synonymous_variant 1.0 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 1.0 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 1.0 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 1.0 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 1.0 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 1.0 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 1.0 ethionamide
Rv0565c 657222 c.249C>G synonymous_variant 1.0 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 1.0 ethionamide
Rv0565c 657242 p.Glu77Lys missense_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 1.0 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 1.0 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 1.0 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 1.0 ethionamide
Rv0565c 657300 c.171C>T synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 1.0 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 1.0 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.95 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.95 ethionamide
Rv0565c 657357 c.112_114delACCinsGG frameshift_variant&missense_variant 0.96 ethionamide Uncertain significance
Rv0565c 657364 p.Thr36Ser missense_variant 0.96 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.93 ethionamide
Rv0565c 657381 c.90A>G synonymous_variant 0.93 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.93 ethionamide
Rv0565c 657560 c.-90G>C upstream_gene_variant 0.95 ethionamide
Rv0565c 657563 c.-93T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657641 c.-171C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657656 c.-186C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657719 c.-249C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 728309 c.-3620_*5892del transcript_ablation 0.99 isoniazid Uncertain significance
hadA 731732 c.-198G>A upstream_gene_variant 0.97 isoniazid
hadA 731741 c.-189G>A upstream_gene_variant 0.98 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.98 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.98 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.99 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.99 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.99 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.99 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.98 isoniazid
hadA 731833 c.-97T>A upstream_gene_variant 0.97 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.86 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.86 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.83 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.81 isoniazid
hadA 731953 c.24T>C synonymous_variant 0.93 isoniazid
hadA 731962 c.33T>C synonymous_variant 0.96 isoniazid
hadA 731968 c.39G>C synonymous_variant 0.96 isoniazid
hadA 731971 c.42T>C synonymous_variant 0.93 isoniazid
hadA 731980 c.51C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
hadA 732004 c.75T>C synonymous_variant 0.96 isoniazid
hadA 732016 c.87C>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
hadA 732025 c.96T>G synonymous_variant 1.0 isoniazid
hadA 732028 c.99A>G synonymous_variant 1.0 isoniazid
hadA 732046 c.117T>C synonymous_variant 1.0 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.98 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.98 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.99 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.99 isoniazid
hadA 732270 p.Glu114Val missense_variant 1.0 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.99 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.99 isoniazid
hadA 732304 c.375C>T synonymous_variant 0.99 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.99 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.99 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Val missense_variant 1.0 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.99 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734078 c.-176C>A upstream_gene_variant 1.0 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 1.0 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 1.0 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.98 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 1.0 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 1.0 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 1.0 rifampicin
nusG 734144 c.-110G>C upstream_gene_variant 1.0 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 1.0 rifampicin
nusG 734175 c.-79_-77delGGTinsCTG upstream_gene_variant 1.0 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 1.0 rifampicin
nusG 734340 c.87T>G synonymous_variant 0.95 rifampicin
nusG 734349 c.96C>T synonymous_variant 0.97 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.98 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.99 rifampicin
nusG 734373 c.120G>C synonymous_variant 0.99 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.99 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.99 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.99 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.99 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734457 c.204C>G synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>G synonymous_variant 1.0 rifampicin
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734595 c.342C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 0.99 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.99 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.99 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.99 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.99 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.98 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734658 c.405A>G synonymous_variant 0.98 rifampicin Not assoc w R
nusG 734661 c.408A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734664 c.411T>G synonymous_variant 0.95 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.98 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsTG frameshift_variant&missense_variant 0.98 rifampicin
nusG 734703 c.450T>C synonymous_variant 1.0 rifampicin
nusG 734709 c.456T>G synonymous_variant 1.0 rifampicin
nusG 734715 c.462G>C synonymous_variant 0.96 rifampicin
nusG 734718 c.465G>C synonymous_variant 1.0 rifampicin
nusG 734719 p.Ser156Ala missense_variant 1.0 rifampicin
nusG 734726 p.Arg158Lys missense_variant 1.0 rifampicin
nusG 734732 p.Ala160Val missense_variant 1.0 rifampicin
nusG 734754 c.501G>C synonymous_variant 1.0 rifampicin
nusG 734757 c.504T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734778 c.525G>C synonymous_variant 0.97 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734792 p.Val180Ala missense_variant 1.0 rifampicin
nusG 734794 p.Val181Ile missense_variant 1.0 rifampicin Uncertain significance
nusG 734820 c.567A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 1.0 rifampicin
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>C synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 1.0 rifampicin
nusG 734882 p.Ala210Gly missense_variant 1.0 rifampicin
nusG 734886 c.633A>G synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734931 c.678A>G synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734949 c.696T>C synonymous_variant 1.0 rifampicin
nusG 734950 p.Gly233Ser missense_variant 1.0 rifampicin
rpoB 759573 c.-234T>C upstream_gene_variant 1.0 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 1.0 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 1.0 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760088 c.282C>G synonymous_variant 0.98 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>T synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.99 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.99 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.99 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.99 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.96 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.99 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.99 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.99 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.98 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.99 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>G synonymous_variant 1.0 rifampicin
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760757 c.951T>C synonymous_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760763 c.957C>T synonymous_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760775 c.969G>C synonymous_variant 1.0 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.99 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.99 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.99 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.99 rifampicin
rpoB 760869 p.Val355Ile missense_variant 1.0 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.97 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.99 rifampicin
rpoB 761189 c.1383T>G synonymous_variant 0.99 rifampicin
rpoB 761213 c.1407G>A synonymous_variant 1.0 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 1.0 rifampicin
rpoB 761231 c.1425C>G synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761301 c.1495C>A synonymous_variant 1.0 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761373 p.Val523His missense_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761723 c.1917_1919delAGAinsG frameshift_variant&synonymous_variant 0.98 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.99 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.99 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.99 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.99 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.99 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.99 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.99 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.99 rifampicin
rpoB 761847 p.Cys681Ser missense_variant 0.99 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.99 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.99 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761930 c.2124G>A synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.99 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.99 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.98 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.98 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.98 rifampicin
rpoC 762512 c.-858C>G upstream_gene_variant 0.89 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 0.99 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762782 c.2976T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.97 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.97 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.97 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.97 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762830 c.3024C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762836 c.-534C>G upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 1.0 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 1.0 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 1.0 rifampicin
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763441 c.72C>G synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763642 c.273G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.99 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763783 c.414G>C synonymous_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763819 c.450G>C synonymous_variant 1.0 rifampicin
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763960 c.591T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763967 p.Gly200Ser missense_variant 1.0 rifampicin
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.99 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Gln missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764282 c.913_915delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764470 c.1101C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.97 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 1.0 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764779 c.1410G>A synonymous_variant 1.0 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 1.0 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765208 c.1839T>C synonymous_variant 1.0 rifampicin
rpoC 765220 c.1851A>G synonymous_variant 1.0 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 1.0 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 1.0 rifampicin
rpoC 765244 c.1875T>G synonymous_variant 1.0 rifampicin
rpoC 765245 c.1877_1878insGCT disruptive_inframe_insertion 1.0 rifampicin
rpoC 765249 p.Leu627Ser missense_variant 1.0 rifampicin
rpoC 765250 c.1882_1884delAGC conservative_inframe_deletion 1.0 rifampicin
rpoC 765287 c.1918C>T synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.99 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.99 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.99 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.99 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.99 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.99 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 1.0 rifampicin
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.99 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.99 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 1.0 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.99 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.99 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 0.99 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.99 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.99 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.99 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.99 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.99 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 1.0 rifampicin
rpoC 766069 c.2700G>A synonymous_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 1.0 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.99 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.99 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766258 c.2889T>C synonymous_variant 1.0 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 1.0 rifampicin
rpoC 766279 c.2910C>G synonymous_variant 0.98 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.99 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.99 rifampicin
rpoC 766327 c.2958C>G synonymous_variant 0.99 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.99 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.99 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.99 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.99 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.99 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766444 c.3075C>G synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766489 c.3120G>T synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766588 c.3219G>A synonymous_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.99 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766978 c.3609C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.99 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>G synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>G synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Ser missense_variant 0.7 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsTG frameshift_variant&missense_variant 0.73 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775898 c.2583G>A synonymous_variant 0.81 clofazimine
bedaquiline
mmpL5 775901 c.2580G>A synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.62 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775912 c.2569C>A synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 0.36 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775937 c.2542_2544delGCGinsTC frameshift_variant&missense_variant 0.69 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775966 p.Ala839Ser missense_variant 0.72 clofazimine
bedaquiline
mmpL5 775970 c.2511G>C synonymous_variant 0.59 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.8 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 0.84 clofazimine
bedaquiline
mmpL5 776008 p.His825Tyr missense_variant 0.36 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776027 c.2454G>C synonymous_variant 0.43 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.48 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 776056 p.Val809Leu missense_variant 0.9 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776063 c.2418C>T synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776076 p.Ala802Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776084 c.2397C>G synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776102 c.2377_2379delATCinsGG frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776120 c.2361C>T synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 776636 p.Glu615Asp missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776646 p.Val612Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776654 c.1827A>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776665 p.Thr606Ala missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776678 c.1803G>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 776693 c.1788C>G synonymous_variant 0.84 clofazimine
bedaquiline
mmpL5 776738 p.Ile581Met missense_variant 0.72 clofazimine
bedaquiline
mmpL5 776744 c.1737C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 776753 c.1728T>C synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 776756 p.Asp575Glu missense_variant 0.65 clofazimine
bedaquiline
mmpL5 777143 c.1338G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777194 c.1287A>G synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777214 p.Ala423Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777245 c.1236G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777251 c.1230C>A synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781189 c.-371T>C upstream_gene_variant 0.92 streptomycin
rpsL 781197 c.-363A>G upstream_gene_variant 0.94 streptomycin
rpsL 781209 c.-351C>G upstream_gene_variant 0.95 streptomycin
rpsL 781224 c.-336T>C upstream_gene_variant 0.96 streptomycin
rpsL 781230 c.-330T>C upstream_gene_variant 0.96 streptomycin
rpsL 781233 c.-327G>C upstream_gene_variant 0.96 streptomycin
rpsL 781234 c.-326G>T upstream_gene_variant 0.96 streptomycin
rpsL 781240 c.-320A>T upstream_gene_variant 0.96 streptomycin
rpsL 781269 c.-291C>T upstream_gene_variant 1.0 streptomycin
rpsL 781270 c.-290A>C upstream_gene_variant 1.0 streptomycin
rpsL 781276 c.-284A>C upstream_gene_variant 1.0 streptomycin
rpsL 781571 c.12C>T synonymous_variant 0.98 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 0.97 streptomycin Uncertain significance
rpsL 781631 c.72G>C synonymous_variant 0.99 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.99 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.99 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.99 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.99 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.99 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.99 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.99 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.99 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.99 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800188 c.-621G>A upstream_gene_variant 1.0 linezolid
rplC 800209 c.-600C>T upstream_gene_variant 1.0 linezolid
rplC 800212 c.-597C>A upstream_gene_variant 1.0 linezolid
rplC 800216 c.-593A>G upstream_gene_variant 1.0 linezolid
rplC 800218 c.-591_-590insT upstream_gene_variant 0.94 linezolid
rplC 800225 c.-584T>C upstream_gene_variant 1.0 linezolid
rplC 800230 c.-579C>T upstream_gene_variant 1.0 linezolid
rplC 800248 c.-561C>T upstream_gene_variant 1.0 linezolid
rplC 800252 c.-557C>A upstream_gene_variant 1.0 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 1.0 linezolid
rplC 800321 c.-488T>C upstream_gene_variant 1.0 linezolid
rplC 800325 c.-484C>A upstream_gene_variant 1.0 linezolid
rplC 800329 c.-480C>T upstream_gene_variant 1.0 linezolid
rplC 800341 c.-468G>C upstream_gene_variant 0.91 linezolid
rplC 800358 c.-450delT upstream_gene_variant 1.0 linezolid
rplC 800382 c.-427G>C upstream_gene_variant 1.0 linezolid
rplC 800383 c.-426T>A upstream_gene_variant 1.0 linezolid
rplC 800386 c.-423T>C upstream_gene_variant 1.0 linezolid
rplC 800399 c.-410A>C upstream_gene_variant 1.0 linezolid
rplC 800406 c.-403T>C upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.99 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800794 c.-15_-9delAGATTGGinsGAGTT upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800817 c.9A>T synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800874 c.66A>G synonymous_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800939 p.Arg44Gln missense_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800955 c.147C>G synonymous_variant 1.0 linezolid
rplC 800967 c.159C>G synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 800994 c.186C>G synonymous_variant 1.0 linezolid
rplC 801004 p.Leu66Val missense_variant 1.0 linezolid
rplC 801009 c.201A>C synonymous_variant 1.0 linezolid
rplC 801012 c.204T>C synonymous_variant 1.0 linezolid
rplC 801019 p.Thr71Ala missense_variant 1.0 linezolid
rplC 801024 c.216C>G synonymous_variant 1.0 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801031 p.Val75Ile missense_variant 1.0 linezolid
rplC 801039 c.231A>G synonymous_variant 1.0 linezolid
rplC 801045 c.237A>C synonymous_variant 1.0 linezolid
rplC 801047 p.Tyr80Phe missense_variant 1.0 linezolid
rplC 801054 c.246G>C synonymous_variant 1.0 linezolid
rplC 801099 c.291T>C synonymous_variant 1.0 linezolid
rplC 801102 c.294G>C synonymous_variant 1.0 linezolid
rplC 801105 c.297A>G synonymous_variant 1.0 linezolid
rplC 801109 c.301T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801114 c.306C>G synonymous_variant 1.0 linezolid
rplC 801127 p.Ala107Thr missense_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801150 c.342G>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>A synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801246 c.438C>G synonymous_variant 1.0 linezolid
rplC 801249 c.441T>G synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>T synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801282 c.474G>C synonymous_variant 1.0 linezolid
rplC 801300 c.492C>G synonymous_variant 1.0 linezolid
rplC 801301 c.493C>A synonymous_variant 0.98 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801336 c.528C>G synonymous_variant 1.0 linezolid
rplC 801339 c.531T>C synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 0.99 linezolid
rplC 801402 c.594T>C synonymous_variant 0.99 linezolid
rplC 801405 c.597T>C synonymous_variant 0.99 linezolid
rplC 801417 c.609T>C synonymous_variant 0.99 linezolid
rplC 801423 c.615G>C synonymous_variant 0.99 linezolid
rplC 801438 c.630T>C synonymous_variant 0.99 linezolid
rplC 801442 p.Ile212Val missense_variant 0.99 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 0.97 linezolid
fbiC 1303437 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303560 c.630G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303701 c.771C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303881 c.951G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303911 c.981G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303923 c.993C>T synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303929 c.999G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303973 p.Gly348Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303981 p.Val351Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303995 c.1065C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304001 c.1071C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304046 c.1116C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304058 c.1128G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304059 c.1129C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304080 p.Ala384Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304517 c.1587C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304523 c.1593G>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304628 c.1698G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_vari