Run ID: SRR14066533
Sample name:
Date: 2024-10-04T18:10:19.268675
Number of reads: 7371796
Percentage reads mapped: 77.84
Median coverage: 213.0
Strain: lineage1.1.1
Spoligotype:
Drug-resistance: Sensitive
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage1.1 | Indo-Oceanic | RD239 | 0.98 |
lineage1 | Indo-Oceanic | RD239 | 0.93 |
lineage1.1.1 | Indo-Oceanic | RD239 | 0.97 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 741 | c.741T>C | synonymous_variant | 0.16 | isoniazid | Not assoc w R - Interim |
dnaA | 756 | c.756T>C | synonymous_variant | 0.17 | isoniazid | |
dnaA | 765 | c.765G>A | synonymous_variant | 0.18 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.17 | isoniazid | |
dnaA | 783 | c.783C>T | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 795 | c.795A>C | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 798 | c.798C>T | synonymous_variant | 0.16 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.19 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 840 | c.840G>A | synonymous_variant | 0.17 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.16 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 885 | c.885T>C | synonymous_variant | 0.16 | isoniazid | |
dnaA | 894 | c.894G>A | synonymous_variant | 0.15 | isoniazid | |
gyrB | 6112 | p.Met291Ile | missense_variant | 0.93 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrB | 6160 | c.921C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6169 | c.930C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6181 | c.942C>A | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6184 | c.945C>A | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6208 | c.969G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6310 | c.-992G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6586 | c.-716T>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>C | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6652 | c.-650C>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6766 | c.-536G>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6769 | c.-533C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6772 | c.1533C>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6794 | p.Ile519Leu | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6797 | p.Gly520Ser | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6847 | c.-455C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6869 | c.-433T>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6898 | c.-404G>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6926 | c.1687T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6950 | c.-352_-350delCTCinsTTG | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6970 | p.Asp577Glu | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6976 | c.-326A>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7012 | c.1773G>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7018 | c.-284G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7024 | c.-278G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7069 | c.-233C>T | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>G | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7081 | c.-221T>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7093 | c.1854T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7114 | c.-188C>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7120 | c.-182T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7123 | c.-179C>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7126 | c.1887G>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7129 | c.-173T>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7150 | c.-152G>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7162 | c.-140C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7463 | c.162G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7469 | c.168C>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7490 | c.189C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7496 | c.195C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7499 | c.198G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7787 | c.486G>A | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7796 | c.495G>A | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7832 | c.531G>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8372 | c.1071G>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | p.Tyr364His | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8426 | c.1125G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8438 | c.1137C>T | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8452 | p.Ala384Val | missense_variant | 0.8 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8537 | c.1236G>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8555 | c.1254G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8573 | c.1272G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8628 | c.1327C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8717 | c.1416C>T | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.16 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8837 | c.1536C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8983 | p.Cys561Ser | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.18 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.15 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9263 | c.1962C>G | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9268 | p.Asn656Thr | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9326 | c.2025G>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13275 | p.Tyr95Cys | missense_variant | 1.0 | isoniazid | Not assoc w R |
Rv0010c | 13298 | p.Ile87Met | missense_variant | 1.0 | isoniazid | Not assoc w R |
Rv0010c | 13460 | c.99T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
Rv0010c | 13482 | p.Ala26Val | missense_variant | 1.0 | isoniazid | Not assoc w R |
fgd1 | 490854 | c.72C>T | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491229 | c.447C>T | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491265 | c.483G>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491286 | c.504G>A | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491328 | c.546C>A | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491340 | c.558C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491343 | c.561C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491355 | c.573C>G | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491388 | c.606C>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491393 | p.Thr204Asn | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491472 | c.690A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 574679 | c.-669C>T | upstream_gene_variant | 0.16 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
mshA | 574683 | c.-665T>C | upstream_gene_variant | 0.16 | isoniazid | Uncertain significance |
ethionamide | ||||||
mshA | 574694 | c.-654C>G | upstream_gene_variant | 0.16 | isoniazid | |
ethionamide | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
mshA | 575725 | c.378C>G | synonymous_variant | 0.16 | isoniazid | |
ethionamide | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
mshA | 575743 | c.396C>T | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
mshA | 575773 | c.426C>A | synonymous_variant | 0.15 | isoniazid | |
ethionamide | ||||||
mshA | 575785 | c.438T>C | synonymous_variant | 0.16 | isoniazid | |
ethionamide | ||||||
mshA | 575806 | c.459G>C | synonymous_variant | 0.16 | isoniazid | |
ethionamide | ||||||
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657690 | c.-220C>A | upstream_gene_variant | 0.15 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.19 | ethionamide | |
nusG | 734116 | c.-138T>C | upstream_gene_variant | 0.98 | rifampicin | Not assoc w R |
nusG | 734439 | c.186C>G | synonymous_variant | 0.17 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.19 | rifampicin | |
nusG | 734460 | c.207G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734469 | c.216C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
nusG | 734472 | c.219T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
nusG | 734475 | c.222T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734508 | c.255C>T | synonymous_variant | 0.78 | rifampicin | Not assoc w R - Interim |
nusG | 734532 | c.279A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
nusG | 734790 | c.537G>C | synonymous_variant | 0.17 | rifampicin | |
nusG | 734814 | c.561G>C | synonymous_variant | 0.18 | rifampicin | |
nusG | 734817 | c.564C>G | synonymous_variant | 0.18 | rifampicin | |
nusG | 734826 | c.573A>C | synonymous_variant | 0.19 | rifampicin | |
mmaA3 | 737874 | c.276C>T | synonymous_variant | 0.15 | isoniazid | |
rpoB | 760124 | c.318C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760172 | c.366G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760313 | c.507G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760331 | c.525G>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760337 | c.531C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760340 | c.534G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.17 | rifampicin | Uncertain significance |
rpoB | 760564 | p.Arg253Leu | missense_variant | 0.15 | rifampicin | |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.17 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760637 | c.831G>A | synonymous_variant | 0.15 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.17 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760971 | c.1165C>A | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761006 | c.1200C>T | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761126 | c.1320G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761132 | c.1326G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327_1329delTTGinsCTC | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761375 | c.1569G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761453 | c.1647C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761457 | p.Pro551Gly | missense_variant | 0.17 | rifampicin | |
rpoB | 761465 | c.1659G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761507 | c.1701G>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761561 | c.1755C>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761564 | c.1758G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.17 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.18 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.18 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761819 | c.2013G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761834 | c.2028T>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761848 | p.Cys681Ser | missense_variant | 0.19 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761867 | c.2061C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.22 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.22 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 762149 | c.2343G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762158 | c.2352G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762161 | c.2355C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.2 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 762389 | c.-981G>A | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 762446 | c.-924C>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762486 | p.Pro894Ala | missense_variant | 0.16 | rifampicin | |
rpoB | 762490 | p.Val895Asp | missense_variant | 0.16 | rifampicin | |
rpoC | 762518 | c.-852C>T | upstream_gene_variant | 0.17 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoC | 762545 | c.-825C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.17 | rifampicin | |
rpoC | 762728 | c.-642C>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 762749 | c.-621C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 762753 | c.2947T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762759 | p.Cys985Ala | missense_variant | 0.18 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 762795 | p.Asp997Asn | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.19 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762813 | p.Met1003Val | missense_variant | 0.21 | rifampicin | |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762868 | p.Tyr1021Phe | missense_variant | 0.26 | rifampicin | |
rpoC | 762890 | c.-480C>T | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763133 | c.-237G>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 763142 | c.-228C>G | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763666 | c.297G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763729 | c.360G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763765 | c.396T>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763768 | c.399C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.23 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763813 | c.444C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.23 | rifampicin | |
rpoC | 763851 | p.Ala161Gly | missense_variant | 0.23 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.25 | rifampicin | |
rpoC | 763876 | c.507A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763884 | p.Ala172Val | missense_variant | 0.74 | rifampicin | Not assoc w R |
rpoC | 763886 | c.517C>A | synonymous_variant | 0.73 | rifampicin | Not assoc w R |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763948 | c.579G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763963 | c.594C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 0.26 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764099 | p.Leu244Ile | missense_variant | 0.24 | rifampicin | |
rpoC | 764110 | c.741C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764194 | p.Glu275Asp | missense_variant | 0.3 | rifampicin | |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764206 | p.Asp279Glu | missense_variant | 0.29 | rifampicin | |
rpoC | 764217 | p.Asn283Ser | missense_variant | 0.27 | rifampicin | |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764255 | c.886C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764326 | c.957G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764353 | c.984G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764377 | c.1008C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | p.Ser338Thr | missense_variant | 0.17 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764479 | c.1110G>A | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764533 | c.1164C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>A | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764611 | c.1242G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764644 | c.1275G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764749 | c.1380G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764833 | c.1464A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764896 | c.1527C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764929 | c.1560G>A | synonymous_variant | 0.23 | rifampicin | |
rpoC | 764932 | c.1563C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764939 | c.1570C>T | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764962 | c.1593G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765016 | c.1647C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765171 | p.Pro601Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 765403 | c.2034G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.18 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765533 | p.Tyr722His | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765547 | c.2178C>A | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765583 | c.2214G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765694 | c.2325G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765724 | c.2355C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365_2367delTTGinsCTC | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765787 | c.2418C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765871 | c.2502T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765985 | c.2616C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765986 | c.2617C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765997 | c.2628T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766027 | c.2658G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766057 | c.2688C>A | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766083 | p.Ala905Glu | missense_variant | 0.15 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766387 | c.3018C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766444 | c.3075C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766582 | c.3213C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766585 | c.3216T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.23 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766708 | c.3339A>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766907 | c.3538C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766978 | c.3609C>A | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 767002 | c.3633G>A | synonymous_variant | 0.21 | rifampicin | |
rpoC | 767032 | c.3663G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767035 | c.3666G>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.26 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767113 | c.3744G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.24 | rifampicin | |
rpoC | 767149 | c.3780C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.19 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781709 | c.150G>C | synonymous_variant | 0.2 | streptomycin | Not assoc w R - Interim |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781718 | c.159C>G | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781742 | c.183C>G | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781811 | c.252C>T | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781817 | c.258G>A | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781820 | c.261G>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781838 | c.279G>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.27 | streptomycin | Uncertain significance |
rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 0.28 | streptomycin | |
rplC | 800357 | c.-452C>A | upstream_gene_variant | 1.0 | linezolid | Not assoc w R |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.14 | linezolid | |
rplC | 800600 | c.-209G>T | upstream_gene_variant | 0.18 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.19 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800690 | c.-119C>T | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800708 | c.-101C>T | upstream_gene_variant | 0.16 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.16 | linezolid | |
rplC | 800735 | c.-74C>G | upstream_gene_variant | 0.17 | linezolid | |
rplC | 801210 | c.402T>G | synonymous_variant | 0.17 | linezolid | Not assoc w R - Interim |
rplC | 801249 | c.441T>G | synonymous_variant | 0.18 | linezolid | |
rplC | 801267 | c.459A>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801309 | c.501C>T | synonymous_variant | 0.18 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801324 | c.516T>C | synonymous_variant | 0.16 | linezolid | |
Rv1129c | 1254543 | c.-9T>G | upstream_gene_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303581 | c.651G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303788 | c.858T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303794 | c.864A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303848 | c.918C>T | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303869 | c.939T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303890 | c.960G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303908 | c.978C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303935 | c.1005G>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303969 | p.Val347Ile | missense_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303980 | c.1050G>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304904 | c.1974G>A | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304911 | c.1981C>T | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304970 | c.2040G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304995 | p.Leu689Met | missense_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305075 | c.2145T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305078 | c.2148A>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305096 | c.2166T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305099 | c.2169T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305126 | c.2196T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1305150 | c.2220C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305153 | c.2223G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305173 | p.Asn748Ser | missense_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305177 | c.2247A>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305198 | c.2268G>T | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305204 | c.2274C>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305215 | p.Ser762Thr | missense_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305219 | c.2289T>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
sigE | 1364691 | c.279T>C | synonymous_variant | 0.16 | pyrazinamide | |
sigE | 1364712 | c.300T>C | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364715 | c.303G>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364733 | p.His107Gln | missense_variant | 0.19 | pyrazinamide | |
sigE | 1364736 | c.324T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364742 | c.330A>G | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364763 | c.351T>C | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364767 | c.355A>C | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364772 | c.360G>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364778 | c.366G>C | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364790 | c.378T>C | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364799 | c.387G>C | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364802 | c.390C>G | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364805 | c.393C>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364820 | c.408A>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364856 | c.444C>G | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364862 | c.450C>G | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364868 | c.456T>C | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364877 | c.465G>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364887 | c.475_477delTTAinsCTG | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364898 | c.486C>T | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364913 | c.501C>G | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364943 | c.531C>T | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364949 | c.537C>T | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364950 | p.Ala180Ser | missense_variant | 0.2 | pyrazinamide | |
sigE | 1364961 | c.549A>G | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364964 | c.552T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364976 | c.564T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364979 | c.567C>G | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364980 | c.568T>C | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364984 | p.Ala191Asp | missense_variant | 0.2 | pyrazinamide | |
sigE | 1365006 | c.594T>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1365015 | c.603G>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1365018 | c.606G>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1365037 | c.625C>T | synonymous_variant | 0.17 | pyrazinamide | |
embR | 1417019 | p.Cys110Tyr | missense_variant | 1.0 | ethambutol | Not assoc w R |
embR | 1417554 | c.-207C>G | upstream_gene_variant | 1.0 | ethambutol | |
embR | 1417793 | c.-446C>T | upstream_gene_variant | 1.0 | ethambutol | |
atpE | 1461227 | c.183G>A | synonymous_variant | 1.0 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.15 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.2 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472040 | n.195T>C | non_coding_transcript_exon_variant | 0.19 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.19 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 0.2 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.16 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 0.15 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.25 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473290 | n.1445delCinsTT | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473815 | n.158T>C | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1474018 | n.361G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474040 | n.383G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474709 | n.1052G>T | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1475202 | n.1545G>C | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475220 | n.1563G>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475297 | n.1640C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475366 | n.1709G>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1475532 | n.1875A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475573 | n.1916G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475617 | n.1960C>G | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475625 | n.1968G>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1475655 | n.1998T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475758 | n.2104delC | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1475765 | n.2111delG | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476035 | n.2378G>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476583 | n.2926G>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1476711 | n.3054G>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1476719 | n.3062C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
inhA | 1673808 | c.-394A>G | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1673870 | c.-332G>T | upstream_gene_variant | 0.16 | isoniazid | |
ethionamide | ||||||
inhA | 1673898 | c.-304C>T | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673901 | c.-301A>G | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673905 | c.-297T>G | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673916 | c.-286A>C | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1673917 | c.-285G>C | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1673922 | c.-280T>C | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1674006 | c.-196T>G | upstream_gene_variant | 0.16 | isoniazid | |
ethionamide | ||||||
inhA | 1674024 | c.-178T>C | upstream_gene_variant | 0.16 | isoniazid | |
ethionamide | ||||||
inhA | 1674336 | c.135G>C | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674342 | c.141T>C | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674348 | c.147C>G | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674352 | p.Thr51Ala | missense_variant | 0.21 | isoniazid | |
ethionamide | Uncertain significance | |||||
inhA | 1674368 | p.Ala56Glu | missense_variant | 0.16 | isoniazid | |
ethionamide | ||||||
inhA | 1674375 | c.174C>G | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674382 | p.Leu61Ile | missense_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674419 | p.Ser73Thr | missense_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674421 | c.220T>C | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674428 | p.Gly76Glu | missense_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674440 | p.Glu80Ala | missense_variant | 0.21 | isoniazid | Uncertain significance |
ethionamide | Uncertain significance | |||||
inhA | 1674443 | p.Ala81Glu | missense_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674450 | c.249G>C | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674455 | p.Gly85Asp | missense_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674465 | c.264C>G | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674471 | c.270G>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674480 | c.279T>C | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674486 | c.285T>C | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674489 | c.288G>C | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674537 | c.336C>A | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674552 | c.351C>G | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674573 | c.372G>C | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674575 | p.Tyr125Phe | missense_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.22 | isoniazid | |
ethionamide | ||||||
inhA | 1674624 | c.423A>T | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674627 | c.426T>C | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1674651 | c.450C>T | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674655 | c.454_456delAGCinsTCG | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674660 | c.459G>T | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674690 | c.489C>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674708 | c.507G>A | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674738 | c.537C>G | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674741 | c.540C>T | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
inhA | 1674742 | p.Lys181Pro | missense_variant | 0.23 | isoniazid | |
ethionamide | ||||||
inhA | 1674750 | c.549T>C | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674771 | c.570C>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.3 | isoniazid | |
ethionamide | ||||||
inhA | 1674816 | c.615T>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.24 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674879 | c.678T>G | synonymous_variant | 0.19 | isoniazid | |
ethionamide | ||||||
rpsA | 1833595 | c.54T>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833604 | c.63C>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833610 | c.69C>T | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833928 | c.387G>A | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834102 | c.561T>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834144 | c.603G>A | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834186 | c.645C>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834234 | c.693G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834297 | c.756C>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834319 | p.Val260Ile | missense_variant | 0.79 | pyrazinamide | Uncertain significance |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834378 | c.837T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834411 | c.870T>G | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834459 | c.918G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834612 | c.1071G>A | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834751 | p.Leu404Ile | missense_variant | 0.16 | pyrazinamide | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853375 | c.-231G>C | upstream_gene_variant | 0.22 | linezolid | |
tsnR | 1853387 | c.-219T>C | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853411 | c.-195C>T | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.25 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1853974 | c.369C>T | synonymous_variant | 1.0 | linezolid | Not assoc w R |
tsnR | 1854045 | p.Tyr147Cys | missense_variant | 1.0 | linezolid | Not assoc w R |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2062922 | p.Ile603Val | missense_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
bacA | 2063106 | c.1623G>A | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
ndh | 2102305 | c.738T>C | synonymous_variant | 0.17 | isoniazid | |
delamanid | ||||||
ethionamide | ||||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2156681 | c.-570C>A | upstream_gene_variant | 1.0 | isoniazid | |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
PPE35 | 2167983 | p.Gly877Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
kasA | 2518220 | c.106C>T | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518234 | c.120G>A | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518245 | p.His44Arg | missense_variant | 0.21 | isoniazid | |
kasA | 2518248 | p.Ala45Val | missense_variant | 0.22 | isoniazid | |
kasA | 2518255 | c.141A>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518273 | c.159G>A | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518279 | c.165T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518280 | c.166C>T | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518283 | p.Ala57Pro | missense_variant | 0.18 | isoniazid | |
kasA | 2518297 | c.183C>T | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518300 | c.186T>A | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518312 | p.Asp66Glu | missense_variant | 0.19 | isoniazid | |
kasA | 2518315 | c.201G>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518321 | c.207C>T | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518323 | p.Ser70Asn | missense_variant | 0.17 | isoniazid | |
kasA | 2518334 | c.220C>A | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518567 | c.453G>T | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518574 | p.Ile154Val | missense_variant | 0.21 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518603 | c.489G>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518624 | c.510C>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518627 | c.513T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518708 | c.594C>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518756 | c.642G>T | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518789 | c.675G>T | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518798 | c.684G>T | synonymous_variant | 0.26 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518837 | c.723G>A | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518843 | c.729T>G | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518867 | c.753G>A | synonymous_variant | 0.18 | isoniazid | |
ahpC | 2726051 | c.-142G>A | upstream_gene_variant | 0.99 | isoniazid | |
ahpC | 2726070 | c.-123G>A | upstream_gene_variant | 1.0 | isoniazid | |
folC | 2746351 | c.1248C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
folC | 2746360 | c.1239T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
folC | 2746378 | c.1221G>T | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
folC | 2746381 | c.1218C>T | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
folC | 2747395 | c.204T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
folC | 2747412 | p.Ser63Gly | missense_variant | 0.19 | para-aminosalicylic_acid | |
folC | 2747414 | p.Arg62Leu | missense_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2747419 | c.180C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2747422 | c.177G>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2747425 | c.174C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2747442 | c.157T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
folC | 2747443 | c.156G>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.17 | kanamycin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783044 | c.999G>T | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783048 | p.Asp332Gly | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783051 | p.Tyr331Phe | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783071 | c.972C>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783083 | c.960G>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.24 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783119 | c.924G>A | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783146 | c.897G>A | synonymous_variant | 0.28 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.28 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | ||||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.28 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.31 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783218 | c.825C>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>A | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783230 | c.813T>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783247 | c.796T>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783263 | c.780G>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783278 | c.765A>G | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783287 | c.756C>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783299 | c.744A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783311 | c.732T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783317 | c.726G>A | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783362 | c.681G>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783371 | c.672A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783374 | c.669G>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783407 | c.636C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783419 | c.624G>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783425 | c.618C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.28 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783499 | c.544T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.25 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783509 | c.534C>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783554 | c.489C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783566 | c.477C>T | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783578 | c.465G>A | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783602 | c.441G>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783611 | c.432C>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783620 | c.423C>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783626 | p.Ala139Ser | missense_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783632 | c.411C>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.2 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783788 | c.255T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783791 | c.252C>G | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2752c | 3064632 | c.1560C>T | synonymous_variant | 0.97 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
Rv2752c | 3065457 | c.735A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065463 | c.729T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065487 | c.705T>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065490 | c.702A>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065493 | c.699G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065496 | c.696G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065499 | c.693A>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065508 | c.684T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065511 | c.681G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065517 | c.675C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065528 | c.664C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065532 | c.660A>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065538 | c.654G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065550 | c.642G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065553 | c.639A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065576 | p.Ala206Ser | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065577 | c.615C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065580 | c.612G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065595 | p.Leu199Phe | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065610 | p.Thr194Ala | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065619 | c.573C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065634 | c.558G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065637 | c.555A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065640 | c.552T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065649 | c.543T>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065652 | c.540C>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065659 | p.Pro178Leu | missense_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3066141 | c.51G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066156 | c.36C>T | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066171 | c.21G>A | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066176 | p.Pro6Thr | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066195 | c.-4A>G | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066231 | c.-40G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066483 | c.-292T>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066930 | c.-739G>A | upstream_gene_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066934 | c.-743G>A | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066966 | c.-775C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066969 | c.-778G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066981 | c.-790T>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066994 | c.-804_-803delCAinsGG | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3067011 | c.-820C>A | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067244 | c.702C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067249 | p.Thr233Ser | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067271 | c.675G>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067274 | c.672C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067277 | c.669C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067284 | p.Ala221Gly | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067287 | p.Ala220Val | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067304 | c.642A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067316 | c.630A>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067349 | c.597G>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067355 | c.591A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067373 | c.573C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067406 | c.540A>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067430 | c.516C>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067466 | c.480G>A | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067470 | p.Asn159Ser | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067472 | c.474C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067802 | c.144C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067814 | c.132T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067826 | c.120C>G | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073956 | c.516G>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073968 | c.504C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3083 | 3448714 | p.Asp71His | missense_variant | 1.0 | ethionamide | Uncertain significance |
lpqB | 3624008 | c.903T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624014 | c.897T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624037 | c.874A>C | synonymous_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624041 | p.Glu290Asp | missense_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624050 | c.861C>G | synonymous_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624077 | c.834G>C | synonymous_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624082 | c.829A>C | synonymous_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624089 | c.822C>G | synonymous_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624094 | c.817A>C | synonymous_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624100 | c.811T>C | synonymous_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624101 | c.810C>G | synonymous_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624107 | c.804C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624116 | c.795A>G | synonymous_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624125 | c.786A>G | synonymous_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624486 | p.Asp142Gly | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3624701 | c.210T>G | synonymous_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624722 | c.189C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624731 | c.180C>G | synonymous_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3624749 | c.162G>A | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3624760 | c.151C>T | synonymous_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
mtrB | 3625095 | p.Glu507Gln | missense_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625135 | c.-225A>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625162 | c.1452T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625189 | c.1425A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625198 | c.-288C>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625222 | c.1392T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625255 | c.-345T>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625258 | c.-348G>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625267 | c.1347T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625276 | c.-366C>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625285 | c.-375G>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625585 | c.-675G>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625592 | p.Ser341Asn | missense_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625615 | p.Arg333Ala | missense_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625675 | c.-765G>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.25 | rifampicin | Uncertain significance |
bedaquiline | ||||||
mtrB | 3625762 | c.852A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625801 | c.-891G>T | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626400 | p.Ile72Val | missense_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626404 | c.210C>G | synonymous_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626407 | c.207C>G | synonymous_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626410 | c.204T>C | synonymous_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626413 | c.201T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626437 | c.177T>C | synonymous_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.22 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626888 | c.-277_-275delTTGinsCTC | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626891 | c.-278G>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626912 | c.438T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626939 | p.Glu137Asp | missense_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626999 | c.-386G>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627116 | c.-503G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627170 | c.-557C>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627187 | c.163T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627188 | c.-577_-575delTTAinsCTG | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627221 | c.-608C>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.2 | rifampicin | |
rpoA | 3877638 | c.870T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoA | 3877656 | c.852T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3877677 | p.Ala277Thr | missense_variant | 0.16 | rifampicin | |
rpoA | 3877680 | c.828G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877746 | c.762G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3877875 | c.633T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877881 | c.627G>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3877900 | p.Ser203Thr | missense_variant | 0.19 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.19 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878019 | c.489A>G | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878046 | c.462T>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878082 | c.426T>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878100 | c.408C>G | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878127 | c.381G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878130 | c.378C>G | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878143 | p.Gly122Asp | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoA | 3878160 | c.348C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3878184 | c.324C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878205 | c.303T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878256 | c.252G>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878264 | p.Ser82Gly | missense_variant | 0.25 | rifampicin | |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878283 | p.Glu75Asp | missense_variant | 0.23 | rifampicin | Uncertain significance |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878301 | c.207C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3878364 | c.144A>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878370 | c.138T>C | synonymous_variant | 0.29 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3878391 | c.117T>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878415 | c.93C>T | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878424 | c.84G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878432 | c.76C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878454 | c.54A>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878458 | p.Asn17Thr | missense_variant | 0.2 | rifampicin | |
rpoA | 3878472 | p.Asp12Glu | missense_variant | 0.16 | rifampicin | |
rpoA | 3878630 | c.-124delC | upstream_gene_variant | 0.99 | rifampicin | Not assoc w R |
rpoA | 3878725 | c.-218A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878737 | c.-230G>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 0.2 | rifampicin | Uncertain significance |
rpoA | 3878749 | c.-242G>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.25 | rifampicin | Uncertain significance |
rpoA | 3878797 | c.-290G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3878806 | c.-299C>A | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3878836 | c.-331_-329delAAGinsGGC | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.22 | rifampicin | Uncertain significance |
rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878890 | c.-383C>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878893 | c.-388_-386delCACinsAAG | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878909 | c.-402A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878917 | c.-410G>C | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878926 | c.-419C>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878947 | c.-440G>A | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878962 | c.-455G>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.18 | rifampicin | Uncertain significance |
rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 0.18 | rifampicin | Uncertain significance |
rpoA | 3878995 | c.-488A>G | upstream_gene_variant | 0.17 | rifampicin | |
rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3879130 | c.-623A>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.17 | rifampicin | |
ddn | 3986636 | c.-208C>G | upstream_gene_variant | 0.18 | pretomanid | |
delamanid | ||||||
ddn | 3986648 | c.-196C>G | upstream_gene_variant | 0.17 | pretomanid | |
delamanid | ||||||
ddn | 3986660 | c.-184C>T | upstream_gene_variant | 0.15 | pretomanid | |
delamanid | ||||||
ddn | 3987083 | c.240C>T | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
ddn | 3987086 | c.243C>T | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4038644 | p.Glu687Asp | missense_variant | 0.17 | pyrazinamide | |
clpC1 | 4038653 | c.2052C>T | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038661 | p.Ser682Thr | missense_variant | 0.15 | pyrazinamide | |
clpC1 | 4038671 | c.2034T>G | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038674 | c.2031C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038721 | c.1984C>T | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038848 | c.1857C>T | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038884 | c.1821C>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038899 | c.1806C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038923 | c.1780_1782delCTAinsTTG | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039070 | c.1635G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039073 | c.1632C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039094 | c.1611C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039136 | c.1569C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039139 | p.Glu522Val | missense_variant | 0.18 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039162 | p.His515Tyr | missense_variant | 0.79 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039186 | c.1519C>T | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039196 | c.1509G>A | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039258 | p.Gln483Glu | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4039259 | p.Glu482Asn | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | p.Leu473Met | missense_variant | 0.22 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039304 | c.1401G>A | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039313 | c.1392C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039319 | c.1386T>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039322 | c.1383T>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4039352 | c.1353C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039361 | c.1344C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039406 | c.1299G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039412 | c.1293T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039415 | p.Glu430Asp | missense_variant | 0.23 | pyrazinamide | Uncertain significance |
clpC1 | 4039430 | c.1275T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039442 | c.1263A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039454 | c.1251A>G | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039463 | c.1242C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039466 | c.1239T>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039484 | c.1221T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039487 | c.1218G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039556 | c.1149G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039559 | c.1146C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039568 | p.Met379Ile | missense_variant | 0.24 | pyrazinamide | Uncertain significance |
clpC1 | 4039576 | p.Ala377Ser | missense_variant | 0.24 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039581 | p.Thr375Ser | missense_variant | 0.23 | pyrazinamide | |
clpC1 | 4039601 | c.1104G>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039621 | c.1084C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>A | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039646 | p.Glu353Ala | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4039670 | c.1035G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039673 | c.1032G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039760 | c.945T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039790 | c.915C>T | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039955 | c.750G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039979 | c.726C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039988 | c.717C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039996 | p.Glu237Gln | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4040517 | p.Val63Ala | missense_variant | 0.91 | pyrazinamide | Not assoc w R - Interim |
glpK | 4138338 | p.Ala473Asp | missense_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138360 | c.1396T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138361 | c.1395C>A | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138376 | p.Val460Ala | missense_variant | 0.18 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
glpK | 4138379 | c.1377T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138382 | c.1374A>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138385 | c.1371A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138391 | c.1365C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138418 | c.1338T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138429 | c.1327T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138451 | c.1305T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138463 | c.1293C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138472 | c.1284G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138478 | c.1278T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138634 | c.1122G>A | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138643 | c.1113A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138646 | c.1110G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138654 | c.1102C>T | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
glpK | 4138661 | c.1095T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138681 | p.Met359Val | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138697 | c.1059C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138703 | c.1053C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138714 | p.Ala348Ser | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138757 | c.997_999delCTAinsTTG | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138796 | c.960A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138799 | c.957T>A | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138808 | c.948G>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139265 | p.Ala164Glu | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4139315 | c.441C>T | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4240726 | c.864G>C | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embC | 4240765 | c.903C>G | synonymous_variant | 0.25 | ethambutol | |
embC | 4240771 | c.909G>C | synonymous_variant | 0.25 | ethambutol | |
embC | 4240780 | c.918T>C | synonymous_variant | 0.25 | ethambutol | |
embC | 4240783 | c.921G>C | synonymous_variant | 0.25 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.25 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4240859 | p.Leu333Val | missense_variant | 0.26 | ethambutol | |
embC | 4240867 | c.1005T>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4240870 | c.1008T>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4240879 | c.1017G>C | synonymous_variant | 0.23 | ethambutol | |
embC | 4240880 | p.Ala340Thr | missense_variant | 0.23 | ethambutol | Uncertain significance |
embC | 4240885 | c.1023T>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4240897 | c.1035C>G | synonymous_variant | 0.23 | ethambutol | Not assoc w R |
embC | 4240900 | c.1038A>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4240921 | c.1059C>G | synonymous_variant | 0.21 | ethambutol | |
embC | 4240924 | c.1062C>G | synonymous_variant | 0.21 | ethambutol | |
embC | 4240935 | p.Val358Ala | missense_variant | 0.19 | ethambutol | Uncertain significance |
embC | 4240945 | c.1083T>C | synonymous_variant | 0.21 | ethambutol | |
embC | 4240948 | c.1086G>A | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embC | 4240951 | c.1089C>G | synonymous_variant | 0.2 | ethambutol | |
embC | 4240954 | p.Ile364Met | missense_variant | 0.21 | ethambutol | |
embC | 4240963 | c.1101G>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4240966 | c.1104G>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4240978 | c.1116G>A | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
embC | 4240983 | p.Ser374Asn | missense_variant | 0.22 | ethambutol | |
embC | 4240990 | c.1128A>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4241020 | c.1158G>C | synonymous_variant | 0.22 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 0.22 | ethambutol | |
embC | 4241038 | c.1176G>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241042 | p.Asn394Asp | missense_variant | 0.74 | ethambutol | Not assoc w R |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4241053 | c.1191G>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241089 | c.1227C>G | synonymous_variant | 0.26 | ethambutol | |
embC | 4241095 | c.1233C>T | synonymous_variant | 0.27 | ethambutol | |
embC | 4241101 | c.1239G>C | synonymous_variant | 0.25 | ethambutol | |
embC | 4241104 | c.1242G>A | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.26 | ethambutol | |
embC | 4241140 | c.1278A>C | synonymous_variant | 0.23 | ethambutol | |
embC | 4241158 | c.1296T>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embC | 4241161 | c.1299C>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embC | 4241162 | c.1300T>C | synonymous_variant | 0.2 | ethambutol | |
embC | 4241179 | c.1317G>A | synonymous_variant | 0.2 | ethambutol | |
embC | 4241185 | c.1323G>A | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
embC | 4241203 | c.1341T>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 0.99 | ethambutol | Not assoc w R |
embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.15 | ethambutol | |
embA | 4243848 | p.Val206Met | missense_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4244096 | c.864C>T | synonymous_variant | 0.99 | ethambutol | Not assoc w R |
embA | 4244933 | c.1701A>G | synonymous_variant | 0.18 | ethambutol | |
embA | 4244936 | c.1704C>G | synonymous_variant | 0.18 | ethambutol | |
embA | 4244960 | c.1728A>G | synonymous_variant | 0.2 | ethambutol | |
embA | 4244978 | c.1746G>C | synonymous_variant | 0.2 | ethambutol | |
embA | 4244980 | p.Val583Ala | missense_variant | 0.2 | ethambutol | |
embA | 4244982 | c.1750T>C | synonymous_variant | 0.21 | ethambutol | |
embA | 4244987 | c.1755T>C | synonymous_variant | 0.22 | ethambutol | |
embA | 4245003 | p.Thr591Ala | missense_variant | 0.23 | ethambutol | Uncertain significance |
embA | 4245008 | c.1776T>C | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
embA | 4245014 | c.1782C>G | synonymous_variant | 0.24 | ethambutol | |
embA | 4245023 | c.1791A>G | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
embA | 4245026 | c.1794T>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245029 | c.1797T>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245032 | c.1800A>C | synonymous_variant | 0.23 | ethambutol | |
embA | 4245041 | c.1809C>G | synonymous_variant | 0.25 | ethambutol | |
embA | 4245053 | c.1821G>C | synonymous_variant | 0.25 | ethambutol | |
embA | 4245060 | c.1828T>C | synonymous_variant | 0.24 | ethambutol | |
embA | 4245083 | c.1851A>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embA | 4245101 | c.1869G>C | synonymous_variant | 0.17 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.17 | ethambutol | |
embA | 4245146 | c.1914G>A | synonymous_variant | 0.17 | ethambutol | |
embA | 4245153 | p.Ile641Val | missense_variant | 0.17 | ethambutol | |
embA | 4245183 | c.1951C>T | synonymous_variant | 0.16 | ethambutol | |
embA | 4245355 | p.Ala708Gly | missense_variant | 0.17 | ethambutol | |
embA | 4245359 | c.2127G>C | synonymous_variant | 0.17 | ethambutol | |
embA | 4245362 | c.2130G>C | synonymous_variant | 0.17 | ethambutol | |
embA | 4245368 | c.2136T>C | synonymous_variant | 0.17 | ethambutol | |
embA | 4245969 | p.Pro913Ser | missense_variant | 0.99 | ethambutol | Not assoc w R |
embB | 4247470 | c.957T>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4247500 | c.987C>G | synonymous_variant | 0.17 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4247550 | p.Ala346Asp | missense_variant | 0.15 | ethambutol | |
embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
embB | 4248052 | c.1539G>T | synonymous_variant | 0.16 | ethambutol | |
embB | 4248070 | c.1557T>C | synonymous_variant | 0.19 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.19 | ethambutol | |
embB | 4248098 | p.Ile529Phe | missense_variant | 0.19 | ethambutol | |
embB | 4248109 | c.1596C>G | synonymous_variant | 0.22 | ethambutol | |
embB | 4248118 | c.1605T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4248119 | p.Ser536Ala | missense_variant | 0.23 | ethambutol | |
embB | 4248122 | p.Leu537Val | missense_variant | 0.24 | ethambutol | |
embB | 4248133 | c.1620C>A | synonymous_variant | 0.23 | ethambutol | |
embB | 4248142 | c.1629T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4248143 | c.1630T>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.25 | ethambutol | Not assoc w R - Interim |
embB | 4248172 | c.1659G>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4248199 | c.1686A>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.2 | ethambutol | Uncertain significance |
embB | 4248220 | c.1707A>G | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
embB | 4249369 | c.2856T>C | synonymous_variant | 0.16 | ethambutol | |
embB | 4249378 | c.2865G>A | synonymous_variant | 0.15 | ethambutol | |
ubiA | 4269077 | p.Ile253Val | missense_variant | 0.16 | ethambutol | |
ubiA | 4269164 | p.Leu224Met | missense_variant | 0.16 | ethambutol | |
ubiA | 4269173 | p.Val221Ile | missense_variant | 0.16 | ethambutol | |
ubiA | 4269387 | p.Glu149Asp | missense_variant | 1.0 | ethambutol | Not assoc w R |
ubiA | 4269606 | c.228T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
ethA | 4327483 | c.-10G>A | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
whiB6 | 4338242 | p.Gln94Glu | missense_variant | 1.0 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338603 | c.-82C>T | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |
gid | 4407873 | c.330G>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R |