Run ID: SRR3675234
Sample name:
Date: 2024-10-04T16:58:37.168819
Number of reads: 439245
Percentage reads mapped: 32.05
Median coverage: 17.0
Strain: La1.6;La3;lineage4.6.4;lineage4.8.1;lineage4.9
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.6.4 | Euro-American | None | 0.06 |
| lineage3.1.2.2 | East-African-Indian | RD750 | 0.08 |
| lineage4 | Euro-American | None | 0.79 |
| lineage1.1.1 | Indo-Oceanic | RD239 | 0.06 |
| lineage4.8.1 | Euro-American (mainly T) | RD219 | 0.05 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.9 |
| La1.7.1 | M.bovis | None | 0.08 |
| La3 | M.orygis | None | 0.12 |
| La1.6 | M.bovis | None | 0.06 |
| lineage6.3.2 | West-Africa 2 | RD702 | 0.06 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
| p.Tyr384Asn | Mutation from literature | |||
| p.Ala388Gly | Mutation from literature | |||
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| n.888G>A | Uncertain significance | Mutation from literature | ||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| rrs | 1472733 | n.888G>A | non_coding_transcript_exon_variant | 0.5 | streptomycin | Uncertain significance | Mutation from literature |
| embB | 4247580 | p.Ala356Val | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
| embB | 4247663 | p.Tyr384Asn | missense_variant | 1.0 | ethambutol | Mutation from literature | |
| embB | 4247676 | p.Ala388Gly | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 534 | c.534T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 558 | c.558G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 561 | c.561C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 567 | c.567C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 570 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 571 | c.571T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 582 | c.582A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 588 | c.588A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 591 | c.591C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1077 | c.1077A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1113 | c.1113A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1122 | c.1122C>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1125 | c.1125G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1128 | c.1128G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1149 | c.1149C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1153 | c.1153T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1164 | c.1164A>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1167 | c.1167A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1176 | c.1176A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1203 | c.1203T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1210 | p.Ala404Ser | missense_variant | 1.0 | isoniazid | |
| dnaA | 1220 | p.Asn407Ser | missense_variant | 1.0 | isoniazid | |
| dnaA | 1236 | c.1236C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1254 | c.1254T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1278 | c.1278T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1284 | c.1284C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1293 | c.1293T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1299 | c.1299G>C | synonymous_variant | 0.95 | isoniazid | Not assoc w R - Interim |
| dnaA | 1302 | c.1302C>G | synonymous_variant | 0.95 | isoniazid | |
| dnaA | 1314 | c.1314A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1317 | c.1317A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1323 | c.1323C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1335 | c.1335G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1338 | c.1338T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1341 | c.1341G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1347 | c.1347C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1353 | c.1353T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1356 | c.1356T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1359 | c.1359G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1368 | c.1368T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1371 | c.1371T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1374 | c.1374G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1377 | c.1377G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1392 | c.1392A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1395 | c.1395G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1404 | c.1404T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1407 | c.1407T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1416 | c.1416C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1431 | c.1431A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1434 | c.1434C>A | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6091 | c.853dupC | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6103 | c.864G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6121 | c.882C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6209 | c.970C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6223 | c.984G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6229 | c.990G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6247 | c.1008G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6262 | c.1023G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6772 | c.1533C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6970 | c.-332C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6994 | c.-308C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7021 | c.-281G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7081 | c.-221T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7520 | c.219G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7559 | c.258G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7577 | c.276C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7760 | c.459C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8189 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8191 | p.Ala297Gly | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8199 | p.Ser300Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8205 | p.Ile302Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8210 | c.909G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8217 | p.Ser306Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8222 | c.921C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8228 | c.927G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8235 | p.Leu312Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8247 | p.Ile316Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8253 | p.Ile318Leu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | p.Ile328Leu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8402 | p.Asp367Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8423 | c.1122G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8438 | c.1137C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8468 | c.1167C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8510 | c.1209G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8537 | c.1236G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8555 | c.1254G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8573 | c.1272G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8595 | p.Ala432Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8618 | c.1317G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8633 | c.1332C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8816 | c.1515C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8954 | c.1653G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8965 | c.1664_1665insG | frameshift_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8968 | c.1668delG | frameshift_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9074 | c.1773G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9131 | c.1830G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9134 | c.1833C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9153 | p.Thr618Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9167 | c.1866C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9188 | c.1887C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9191 | c.1890G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9218 | c.1917C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9251 | c.1950G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9257 | c.1956C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9275 | c.1974G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9276 | c.1975C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9299 | c.1998G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9300 | p.Ala667Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9344 | c.2043C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491022 | c.240C>G | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491031 | c.249C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491038 | p.Ile86Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491082 | c.300T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491083 | p.Val101Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491091 | c.309T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491137 | p.Glu119Gln | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491144 | p.Ala121Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491169 | c.387C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491219 | p.Asp146Gly | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491226 | c.444C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491229 | c.447C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491292 | c.510G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 0.86 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491302 | p.Ile174Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491331 | c.549G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491340 | c.558C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491343 | c.561C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491349 | c.567T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491355 | c.573C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491391 | c.609C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491393 | p.Thr204Lys | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491397 | p.Glu205Asp | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491415 | c.633A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491418 | c.636A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491421 | c.639A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491430 | c.648T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491436 | c.654T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491442 | c.660A>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491443 | p.Ser221Asn | missense_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491453 | p.Gly224Asp | missense_variant | 1.0 | pretomanid | |
| delamanid | Uncertain significance | |||||
| clofazimine | Uncertain significance | |||||
| fgd1 | 491472 | c.690A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491559 | c.777G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491574 | c.792C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491583 | c.801G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491661 | c.879C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491673 | c.891A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491679 | c.897A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491686 | p.Thr302Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| mshA | 574688 | c.-660G>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 574694 | c.-654C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574712 | c.-636A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574718 | c.-630A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574724 | c.-624T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574731 | c.-617A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574739 | c.-609T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574742 | c.-606G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574763 | c.-585T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 574782 | c.-566C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575051 | c.-297A>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 575052 | c.-296G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575060 | c.-288G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575063 | c.-285T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575072 | c.-276G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575075 | c.-273T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 575530 | c.183C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575536 | c.189T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575542 | c.195C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575560 | c.213C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575561 | p.Met72Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575571 | p.Ser75Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575587 | c.240C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575590 | c.243T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575629 | c.282A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575632 | c.285G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575635 | c.288A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575641 | c.294A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575649 | p.Val101Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575665 | c.318G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575786 | p.Tyr147His | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575824 | c.477T>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575875 | c.528C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575887 | c.540G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575920 | c.573C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575923 | p.Gly193Pro | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575950 | c.603C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575965 | c.618C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575977 | c.630G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575980 | c.633T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575984 | c.637T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575992 | c.645C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 576046 | c.699A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 576049 | c.702A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 576070 | c.723T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 576077 | c.730C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
| ethionamide | Not assoc w R - Interim | |||||
| ccsA | 620145 | c.255T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620160 | c.270A>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620167 | p.Ala93Thr | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620170 | p.Cys94Ser | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620173 | p.Val95Ile | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620187 | c.297C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620198 | p.Gln103Leu | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620257 | p.Ile123Leu | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620269 | p.Val127Ile | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620275 | c.385C>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620284 | p.Ala132Pro | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620295 | c.405G>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620307 | c.417C>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620319 | c.429C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620409 | c.519C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| ccsA | 620433 | c.543C>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| ccsA | 620710 | p.Val274Ile | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620715 | c.825C>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620742 | c.852G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620748 | c.858T>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620758 | c.868_870delCGCinsAGG | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620766 | c.876C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620769 | c.879C>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620784 | c.894C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620787 | c.897C>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620808 | c.918T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv0565c | 656358 | c.1113T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656364 | c.1107T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656367 | c.1104G>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656370 | c.1101T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656380 | p.Glu364Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656391 | p.Leu360Met | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656396 | p.Ser359Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656403 | c.1068C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656412 | c.1059T>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656418 | c.1053A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656423 | c.1048T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656447 | p.Ile342Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656448 | c.1023T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656454 | c.1017G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656457 | c.1014T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656469 | c.1002T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656476 | p.Lys332Ala | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656481 | c.990A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656484 | c.987T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656487 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656502 | c.969C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656511 | c.960T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656539 | p.Ser311Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656542 | p.Thr310Ser | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656546 | p.Ile309Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656568 | c.903G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656924 | p.Ile183Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656926 | p.Lys182Arg | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657267 | c.204G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657303 | c.168C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657317 | c.154C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657324 | c.147C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657342 | c.129T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657347 | c.124A>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657348 | c.123A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 732076 | c.147G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732079 | c.150T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732085 | c.156C>G | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732094 | c.165T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732106 | c.177T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732130 | c.201C>G | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732133 | c.204G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732134 | p.Ala69Ser | missense_variant | 1.0 | isoniazid | |
| hadA | 732151 | c.222T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732154 | c.225G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732164 | p.Thr79Val | missense_variant | 1.0 | isoniazid | |
| hadA | 732167 | p.Ala80Thr | missense_variant | 1.0 | isoniazid | |
| hadA | 732172 | p.Glu81Asp | missense_variant | 1.0 | isoniazid | |
| hadA | 732173 | p.Ala82Gln | missense_variant | 1.0 | isoniazid | |
| hadA | 732190 | c.261A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732209 | p.Glu94Gln | missense_variant | 1.0 | isoniazid | |
| hadA | 732214 | c.285A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732234 | p.Lys102Arg | missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732238 | c.309G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732250 | c.321C>G | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732253 | c.324T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732259 | c.330T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732279 | p.Gly117Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732319 | c.390G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732328 | p.Asp133Glu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732329 | p.Leu134Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732334 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732369 | p.Gly147Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732389 | p.Ser154Thr | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
| nusG | 734409 | c.156T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734466 | c.213G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734470 | c.217_219delCTTinsTTG | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734502 | c.249G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734566 | c.313C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734781 | c.528A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734784 | c.531G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734792 | p.Val180Ala | missense_variant | 1.0 | rifampicin | |
| nusG | 734800 | p.Val183Ile | missense_variant | 1.0 | rifampicin | |
| nusG | 734814 | c.561G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734826 | c.573A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734841 | c.588G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734865 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734870 | p.Ser206Asn | missense_variant | 1.0 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| mmaA3 | 737555 | c.595C>A | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737562 | c.588A>G | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737577 | c.573C>G | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737592 | c.558C>G | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737598 | p.Ile184Val | missense_variant | 1.0 | isoniazid | |
| mmaA3 | 737610 | c.540A>G | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737613 | c.537C>T | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737618 | c.532T>C | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737619 | c.531C>G | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737622 | c.528C>G | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737630 | p.Ser174Ala | missense_variant | 1.0 | isoniazid | |
| mmaA3 | 737646 | c.504C>T | synonymous_variant | 1.0 | isoniazid | |
| rpoB | 759681 | c.-125_-124delGT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759715 | c.-92_-91delGAinsT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759726 | c.-81A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759732 | c.-75C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760172 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760454 | c.648C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760514 | c.708C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760528 | p.Gln241Arg | missense_variant | 1.0 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760856 | c.1050C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760934 | c.1128C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761171 | c.1365C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761196 | c.1390C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761273 | c.1467T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761309 | c.1503C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761333 | c.1527G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761336 | c.1530C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761339 | c.1533C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761345 | c.1539G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761348 | c.1542C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761357 | c.1551G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761375 | c.1569G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761540 | c.1734C>G | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761552 | c.1746G>C | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.89 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761720 | c.1915_1916delGA | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 761724 | p.Glu640Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761728 | c.1923_1924insCC | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761819 | c.2013G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761840 | c.2034C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761876 | c.2070C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761913 | p.Asp703Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761921 | c.2115C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761969 | c.2163G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762011 | c.2205G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762020 | c.2214G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762023 | c.2217C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762119 | c.2313C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762218 | c.2412T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762297 | c.2491C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762490 | p.Val895Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.92 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 0.92 | rifampicin | Uncertain significance |
| rpoC | 762521 | c.-849C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763052 | c.-318G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763076 | c.-294C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763082 | c.-288C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763184 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763537 | c.168C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763600 | c.231C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763648 | c.279C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763768 | c.399C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763790 | p.Glu141Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 763851 | p.Ala161Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 763855 | c.486C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763871 | p.Gly168Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763927 | c.558C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763948 | c.579G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763963 | c.594C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763978 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764110 | c.741C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764217 | p.Asn283Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 764245 | c.876C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764339 | c.970C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764429 | c.1060C>T | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764438 | c.1069_1071delCTGinsTTA | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764443 | c.1074C>T | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764455 | c.1086G>T | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764458 | c.1089G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764467 | c.1098C>T | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764533 | c.1164C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764551 | c.1182G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764656 | c.1287C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764695 | c.1326T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764749 | c.1380G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764830 | c.1461C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764851 | c.1482C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764858 | c.1489_1491delTTGinsCTA | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764861 | c.1492C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764867 | c.1498_1500delCGCinsAGG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764875 | c.1506C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764881 | c.1512G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764885 | c.1516_1518delCGGinsAGA | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765307 | c.1938C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765583 | c.2214G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765612 | p.His748Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765673 | p.Asp768Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765823 | c.2454C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765934 | c.2565C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765985 | c.2616C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766009 | c.2640G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766054 | c.2685C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766063 | c.2694C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766081 | c.2712T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766084 | c.2715A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766085 | p.Pro906Ala | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766142 | c.2773C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766148 | p.Thr927Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766168 | c.2799C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766178 | p.Ile937Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 766185 | p.Glu939Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766189 | c.2820T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766193 | p.Gln942Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766204 | c.2835C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766207 | c.2838T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766211 | p.Glu948Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 766216 | c.2847T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766222 | c.2853T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766231 | c.2862T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766234 | c.2865T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766237 | c.2868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766240 | c.2871T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766243 | c.2874C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766258 | c.2889T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766270 | c.2901G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766274 | p.Ala969Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766280 | p.Ser971Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766285 | c.2916C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766312 | c.2943T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766486 | c.3117A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766504 | c.3135G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766627 | c.3258G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766658 | p.Arg1097Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766915 | p.Asp1182Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766923 | p.Glu1185Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766931 | p.Ala1188Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766978 | c.3609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767032 | c.3663G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767152 | c.3783T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767188 | c.3819G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767242 | p.Gln1291His | missense_variant | 1.0 | rifampicin | |
| mmpL5 | 775851 | p.Ser877Thr | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775856 | c.2625T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775865 | c.2616T>C | synonymous_variant | 0.91 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775883 | p.Ile866Leu | missense_variant | 0.91 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775886 | c.2595A>C | synonymous_variant | 0.91 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.93 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775913 | p.Ala856Ser | missense_variant | 0.93 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775916 | c.2565T>G | synonymous_variant | 0.92 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.86 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.85 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.85 | bedaquiline | |
| clofazimine | ||||||
| rpsL | 781130 | c.-430_-429delACinsGT | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781137 | c.-423G>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781138 | c.-422C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781143 | c.-417T>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781158 | c.-402C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781161 | c.-399G>A | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781164 | c.-396T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781608 | p.Ser17Gly | missense_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781820 | c.261G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781835 | c.276T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800555 | c.-254C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800576 | c.-233C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.96 | linezolid | |
| rplC | 800684 | c.-125G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800690 | c.-119C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800799 | c.-10_-8delGGAinsC | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800874 | c.66A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800880 | c.72A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801171 | c.363A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801174 | c.366T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801201 | c.393C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801222 | c.414T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801267 | c.459A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801288 | c.480G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801315 | c.507G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801339 | c.531T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801396 | c.588T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801400 | p.Val198Ile | missense_variant | 1.0 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801432 | c.624C>G | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303217 | p.Arg96His | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303219 | c.289_291delTTAinsCTG | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303227 | c.297G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303242 | c.312T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303248 | c.318G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303268 | p.Lys113Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303272 | c.342A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303275 | c.345C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303281 | c.351A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303285 | p.Ser119Ala | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303288 | p.Ser120Gly | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303292 | p.Thr121Met | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303297 | p.Met123Leu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303321 | p.Val131Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303449 | c.519C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303455 | c.525C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303464 | c.534A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303480 | p.Gln184Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303492 | c.562T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303501 | c.571C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303614 | c.684C>T | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303623 | c.693C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303638 | c.708A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303660 | p.Val244Thr | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303731 | c.801A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303732 | p.Ser268Pro | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303749 | c.819G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303755 | c.825T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303789 | p.Ile287Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303794 | c.864A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303806 | c.876G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303809 | c.879G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303821 | c.891C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303846 | p.Phe306Met | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303860 | c.930A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303869 | c.939T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303884 | c.954T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303905 | c.975G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303920 | c.990C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303935 | c.1005G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303947 | c.1017T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303948 | p.Gly340Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303956 | c.1026A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303965 | c.1035G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303969 | p.Val347Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303989 | c.1059C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303998 | c.1068T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304001 | c.1071C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304031 | c.1101C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304058 | p.Glu376Asp | missense_variant | 1.0 | pretomanid | |
| delamanid | Uncertain significance | |||||
| clofazimine | ||||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304067 | c.1137G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304070 | c.1140C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304091 | p.Asp387Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304096 | p.Val389Ala | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304115 | c.1185A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304127 | c.1197A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304133 | c.1203G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304136 | c.1206C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304169 | c.1239T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304172 | c.1242G>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304184 | c.1254G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304199 | c.1269C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304637 | c.1707G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304671 | p.Val581Thr | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304675 | p.Gly582Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304694 | c.1764A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304742 | c.1812T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304799 | c.1869G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304853 | c.1923C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304883 | p.Glu651Asp | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304910 | c.1980G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304913 | c.1983G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304916 | c.1986T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304925 | c.1995G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304940 | c.2010A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304949 | c.2019C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304970 | c.2040G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304983 | c.2053C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304995 | c.2065T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305033 | c.2103T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305042 | c.2112A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305045 | c.2115A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305066 | c.2136T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305069 | c.2139G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305074 | p.Ser715Thr | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305078 | c.2148A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305090 | c.2160C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305096 | c.2166T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305099 | c.2169T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| sigE | 1364643 | c.231C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364649 | c.237C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364661 | c.249C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364667 | c.255T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364676 | c.264C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364691 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364712 | c.300T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364766 | c.354C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364772 | c.360G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364796 | c.384G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364799 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364802 | c.390C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364805 | c.393C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364808 | c.396C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364811 | c.399A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364814 | c.402C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364838 | c.426C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364847 | c.435G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364856 | c.444C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364865 | c.453G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364868 | c.456T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364887 | c.475_477delTTAinsCTG | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364910 | c.498G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364952 | c.540A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364958 | c.546G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.63 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472658 | n.813G>A | non_coding_transcript_exon_variant | 0.41 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.41 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472690 | n.845C>A | non_coding_transcript_exon_variant | 0.5 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472716 | n.871C>T | non_coding_transcript_exon_variant | 0.37 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.95 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1473259 | n.1414C>T | non_coding_transcript_exon_variant | 0.33 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474527 | n.870T>C | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
| linezolid | ||||||
| rrl | 1474529 | n.872A>G | non_coding_transcript_exon_variant | 0.64 | capreomycin | |
| linezolid | ||||||
| rrl | 1474537 | n.880G>A | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474540 | n.883T>C | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
| linezolid | ||||||
| rrl | 1474542 | n.885A>G | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
| linezolid | ||||||
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | |
| linezolid | ||||||
| rrl | 1475655 | n.1998T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475896 | n.2239A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
| linezolid | ||||||
| rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475906 | n.2249C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475916 | n.2259C>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475937 | n.2280A>T | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475945 | n.2288C>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
| linezolid | ||||||
| rrl | 1475952 | n.2295A>G | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475970 | n.2313C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475975 | n.2318C>T | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475977 | n.2320A>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.88 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476332 | n.2675G>C | non_coding_transcript_exon_variant | 0.86 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476338 | n.2681C>T | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476353 | n.2696G>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476382 | n.2725A>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476383 | n.2726T>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476425 | n.2768G>T | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.84 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.84 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1674237 | c.36T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674239 | p.Ser13Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674243 | c.42A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674249 | c.48C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674279 | c.78A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674285 | c.84A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674300 | c.99C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674304 | p.Gln35Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674315 | c.114C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674342 | c.141T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674352 | p.Thr51Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | Uncertain significance | |||||
| inhA | 1674387 | c.186A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674570 | c.369G>C | synonymous_variant | 0.93 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674576 | c.375T>C | synonymous_variant | 0.93 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 0.93 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674628 | p.Ser143Gly | missense_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674654 | c.453G>C | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674660 | c.459G>T | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674663 | c.462G>C | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674714 | c.513C>G | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674726 | c.525G>A | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674729 | c.528G>C | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674750 | c.549T>C | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 0.96 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674765 | c.564C>T | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674771 | c.570C>G | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674777 | c.576C>G | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674792 | c.591G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674816 | c.615T>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674825 | c.624C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| inhA | 1674846 | c.645C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674849 | p.Gln216His | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674876 | c.675C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674879 | c.678T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674883 | p.Ile228Leu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674933 | c.732G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674939 | c.738G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674942 | c.741T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674945 | p.Asp248Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674957 | c.756G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674966 | c.765T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674967 | p.Asp256Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674970 | p.Ile257Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674993 | c.792G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674994 | p.His265Ser | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833256 | c.-286C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833265 | c.-277A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833268 | c.-274C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833271 | c.-271G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833273 | c.-269G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833280 | c.-262G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833283 | c.-259C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833578 | p.Val13Ile | missense_variant | 0.86 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833613 | c.72C>A | synonymous_variant | 0.85 | pyrazinamide | |
| rpsA | 1833625 | c.84A>G | synonymous_variant | 0.89 | pyrazinamide | |
| rpsA | 1833673 | c.132C>A | synonymous_variant | 0.91 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834051 | c.510G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834411 | c.870T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834432 | c.891G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834474 | c.933C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834654 | p.Glu371Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834788 | p.Ala416Gly | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853360 | c.-246G>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853441 | c.-165C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853444 | c.-162C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853447 | c.-159C>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853450 | c.-156G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853941 | c.336G>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853942 | p.Thr113Ala | missense_variant | 1.0 | linezolid | |
| tsnR | 1853954 | p.Arg117Gly | missense_variant | 1.0 | linezolid | |
| tsnR | 1853968 | c.363C>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853971 | c.366G>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853978 | p.Val125Leu | missense_variant | 1.0 | linezolid | |
| tsnR | 1854004 | c.399T>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1854007 | c.402C>G | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1854024 | p.Ala140Gly | missense_variant | 1.0 | linezolid | |
| tsnR | 1854030 | p.Arg142His | missense_variant | 1.0 | linezolid | |
| tsnR | 1854034 | c.429C>T | synonymous_variant | 1.0 | linezolid | |
| ndh | 2101777 | c.1266C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | ||||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2101783 | c.1260T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101795 | c.1248G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101804 | c.1239T>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101838 | p.Ala402Val | missense_variant | 1.0 | isoniazid | Uncertain significance |
| delamanid | ||||||
| ethionamide | Uncertain significance | |||||
| ndh | 2101858 | p.Ile395Met | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101873 | c.1170T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101888 | p.Val385Leu | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101891 | c.1152C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2101912 | c.1131G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101920 | c.1123A>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101924 | c.1119T>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101936 | c.1107G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101939 | c.1104A>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101960 | c.1083A>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101970 | p.Glu358Ala | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101980 | p.Asn355Asp | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101984 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101990 | c.1053G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102009 | p.Ser345Asn | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102020 | c.1023A>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102023 | c.1020G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102026 | c.1017G>T | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102050 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102059 | c.984T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2102065 | c.978G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102068 | c.975T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102077 | c.966T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102083 | c.960G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102131 | p.Gln304Lys | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102140 | c.903C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102167 | c.876A>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102176 | c.867T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102193 | p.Arg284Gly | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102194 | c.849T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102201 | p.Ser281Gln | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102203 | c.840T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102206 | c.837G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102209 | c.834C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102212 | c.831G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102221 | c.822G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2102230 | c.813G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102247 | p.Val266Ile | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102269 | c.774C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102287 | c.756C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102311 | c.732G>A | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102317 | c.726A>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102320 | c.723G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102341 | c.702C>A | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102344 | c.699T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102366 | p.Ala226Glu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102377 | c.666A>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102382 | c.661C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102389 | c.654G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102392 | c.651C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102401 | c.642T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102407 | c.636T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102425 | c.618G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102668 | c.375T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102671 | c.372T>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102680 | c.363T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102683 | c.360T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102712 | p.Pro111Ser | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102718 | p.Gln109Glu | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102809 | c.234G>A | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102812 | c.231T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| katG | 2155590 | c.522A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155596 | c.516G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155614 | p.Val166Ile | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155617 | c.495T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155632 | c.480A>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155637 | p.Leu159Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155641 | p.Lys157Asn | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155676 | c.436C>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155696 | p.Ala139Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155704 | c.408C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
| pncA | 2289871 | c.-630T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289874 | c.-633C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289880 | c.-639T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289907 | c.-666A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289913 | c.-672T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289916 | c.-675A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289920 | c.-679C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289928 | c.-687C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289940 | c.-699C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289943 | c.-702T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289948 | c.-707C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289949 | c.-708A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289961 | c.-720C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289964 | c.-723C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289970 | c.-729C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289994 | c.-753A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289997 | c.-756G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290006 | c.-765T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290009 | c.-768A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290015 | c.-774A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290030 | c.-791_-789delAATinsCAC | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290034 | c.-794_-793delGCinsAG | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290042 | c.-801T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290072 | c.-831T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290075 | c.-834C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290084 | c.-843T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290087 | c.-846T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| kasA | 2517920 | c.-195G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518195 | c.81G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518226 | p.Ala38Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2518245 | p.His44Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518297 | c.183C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518483 | c.369C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518492 | c.378C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518571 | p.Val153Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518579 | c.465T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518594 | c.480C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518603 | c.489G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518627 | c.513T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518657 | c.543G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518663 | c.549T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518681 | c.567C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518697 | p.Cys195Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518717 | c.603C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518798 | c.684G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518843 | c.729T>G | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518849 | c.735G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518855 | c.741C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518877 | p.Lys255Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518893 | p.Lys260Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518898 | c.784T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518907 | c.793T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518912 | c.798G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518921 | c.807T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519107 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519110 | p.Asp332Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2519112 | p.Gln333Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2519137 | c.1023T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519152 | c.1038G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519167 | c.1053T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519176 | c.1062G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519179 | c.1065G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519182 | c.1068G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519191 | c.1077G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519192 | c.1078C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519197 | c.1083G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519200 | c.1086G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519203 | c.1089C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519215 | c.1101C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519221 | c.1107G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519224 | c.1110C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519239 | c.1125A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519263 | c.1149C>T | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726303 | c.111T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726304 | p.Ile38Leu | missense_variant | 0.91 | isoniazid | |
| ahpC | 2726312 | c.120T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726318 | p.Glu42Asp | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726322 | p.Pro44Glu | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726336 | c.144G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726348 | c.156T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726366 | c.174G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726369 | c.177C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726378 | c.186T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726397 | p.Ser69Gly | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726408 | c.216T>C | synonymous_variant | 1.0 | isoniazid | |
| folC | 2746657 | c.942T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746663 | c.936T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746990 | p.Asp203Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746999 | c.600T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747002 | c.597T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747007 | p.Ser198Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747011 | c.588G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747023 | c.576C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747032 | c.567A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747036 | p.Asn188Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747059 | c.540T>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747062 | c.537A>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747070 | p.Met177Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747074 | c.525G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747302 | c.297A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747341 | c.258C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747359 | c.240C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747365 | c.234G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747371 | c.228C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747395 | c.204T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747407 | c.192T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747412 | p.Ser63Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747414 | p.Arg62Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747419 | c.180C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747442 | c.157T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747443 | c.156G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| Rv2477c | 2782393 | c.1650C>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782399 | c.1644T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782405 | c.1638A>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782408 | c.1635T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782414 | p.Asp543Glu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782420 | c.1623T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782432 | c.1611G>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782444 | c.1599G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782475 | p.Phe523Tyr | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782481 | p.Lys521Arg | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782501 | c.1542T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782504 | c.1539G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782522 | c.1521G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782531 | c.1512C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782537 | c.1506T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782837 | c.1206C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782847 | p.Arg399Lys | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782849 | c.1194G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782867 | p.Ala392Asp | missense_variant | 0.9 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782879 | c.1164C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782913 | p.Ser377Thr | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782927 | p.Thr372Gln | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782981 | c.1062G>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783017 | c.1026C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783020 | c.1023G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783323 | c.720C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783329 | c.714G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783335 | c.708C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783338 | c.705C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783347 | c.696C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783371 | c.672A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783407 | c.636C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | c.618C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783499 | c.544T>C | synonymous_variant | 0.96 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783510 | p.Pro178His | missense_variant | 0.95 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783526 | c.517C>T | synonymous_variant | 0.94 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783557 | c.486T>C | synonymous_variant | 0.95 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783569 | c.474C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||