TB-Profiler result

Run: SRR1180147
Summary

Run ID: SRR1180147

Sample name:

Date: 2024-10-04T16:47:02.546343

Number of reads: 1861391

Percentage reads mapped: 44.33

Median coverage: 39.0

Strain: lineage2.2.1.1

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.8.1 M.bovis None 0.06
lineage2 East-Asian RD105 0.93
lineage2.2.1 East-Asian (Beijing) RD105;RD207;RD181 0.94
lineage2.2 East-Asian (Beijing) RD105;RD207 0.97
lineage2.2.1.1 East-Asian (Beijing) RD105;RD207;RD181;RD150 0.98
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Met482Ile Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
embB 4247448 p.His312Arg missense_variant 0.54 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.25 ethambutol Mutation from literature
embB 4247959 p.Met482Ile missense_variant 0.27 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 777 c.777A>G synonymous_variant 0.19 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.2 isoniazid Not assoc w R - Interim
dnaA 885 c.885T>C synonymous_variant 0.22 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.24 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.25 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.24 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.27 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.23 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.2 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.2 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.31 isoniazid
dnaA 1038 c.1038A>C synonymous_variant 0.24 isoniazid
dnaA 1050 c.1050G>A synonymous_variant 0.32 isoniazid
dnaA 1053 c.1053C>T synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 1077 c.1077A>G synonymous_variant 0.49 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.53 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.41 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.5 isoniazid
dnaA 1107 c.1107C>T synonymous_variant 0.36 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.46 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>C synonymous_variant 0.43 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.41 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.37 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 0.36 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 0.25 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.25 isoniazid
dnaA 1180 c.1180C>T synonymous_variant 0.26 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 0.41 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.42 isoniazid
dnaA 1199 p.Arg400His missense_variant 0.56 isoniazid Uncertain significance
dnaA 1203 c.1203T>C synonymous_variant 0.37 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.33 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.33 isoniazid
dnaA 1224 c.1224C>G synonymous_variant 0.31 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.28 isoniazid
dnaA 1239 c.1239G>A synonymous_variant 0.28 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.44 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.48 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.47 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.35 isoniazid
dnaA 1291 c.1291_1293delCTTinsTTA synonymous_variant 0.33 isoniazid
dnaA 1299 c.1299G>T synonymous_variant 0.32 isoniazid
dnaA 1317 c.1317A>C synonymous_variant 0.41 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 0.39 isoniazid Not assoc w R - Interim
dnaA 1329 c.1329A>G synonymous_variant 0.42 isoniazid
dnaA 1332 c.1332A>G synonymous_variant 0.4 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 0.39 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 0.39 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.32 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.32 isoniazid Not assoc w R - Interim
dnaA 1371 c.1371T>G synonymous_variant 0.34 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 0.34 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.36 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.37 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.37 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.37 isoniazid
dnaA 1428 c.1428C>A synonymous_variant 0.32 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.32 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 0.33 isoniazid
dnaA 1437 c.1437G>A synonymous_variant 0.33 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.38 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.38 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.3 isoniazid
dnaA 1470 c.1470C>G synonymous_variant 0.25 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 0.31 isoniazid Not assoc w R - Interim
dnaA 1479 c.1479C>T synonymous_variant 0.25 isoniazid
dnaA 1500 c.1500C>G synonymous_variant 0.25 isoniazid
dnaA 1506 c.1506T>G synonymous_variant 0.26 isoniazid
gyrB 5254 c.15A>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 5284 c.45G>A synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrB 5287 c.48T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrB 5293 c.54C>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 5302 c.63A>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrB 5305 c.66G>A synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrB 5308 c.69G>A synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrB 6109 c.870G>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.21 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrB 6145 c.906C>T synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrB 6151 c.912C>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrB 6157 c.918C>T synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrB 6187 c.948C>T synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 6202 c.963C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6205 c.966C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6247 c.1008G>A synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrB 6259 p.Asp340Glu missense_variant 0.36 levofloxacin
moxifloxacin
gyrB 6262 c.1023G>A synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrB 6266 p.Pro343Ala missense_variant 0.21 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrB 6283 c.1044C>T synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6331 c.-971A>G upstream_gene_variant 0.49 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6355 c.-947G>A upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6362 c.-940_-938delTTGinsCTA upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.42 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 6721 c.1482C>T synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6730 c.-572A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6781 c.-521C>T upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6832 c.-470C>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6835 c.-467C>T upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6847 c.-455C>T upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrB 6850 c.1611C>A synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6856 c.1617T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6866 c.-436C>T upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>T upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6941 c.-361C>T upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.18 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7388 c.87C>A synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7424 c.123G>A synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7427 c.126G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7433 c.132G>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7625 c.324G>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7793 c.492G>T synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 7835 c.534A>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7838 c.537C>T synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8096 c.795T>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8213 c.912C>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8228 c.927G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 8252 c.951G>A synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.3 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8321 c.1020C>T synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8337 c.1036_1038delCTAinsTTG synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8375 c.1074G>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.28 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8486 c.1185T>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8510 c.1209G>A synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8528 c.1227G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8576 c.1275C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8609 c.1308G>C synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8636 c.1335A>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>T synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8664 c.1363C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8723 c.1422G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.27 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.34 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.26 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.26 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 8855 c.1554C>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8930 c.1629C>T synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>A synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8957 c.1656C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8981 c.1680G>C synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8983 p.Cys561Ser missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>A synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.58 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.19 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>A synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.39 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9065 c.1764C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.35 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.36 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.36 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9185 c.1884C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9192 c.1891C>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9203 c.1902G>A synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>T synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.28 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 9401 c.2100G>A synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>A synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.2 levofloxacin
moxifloxacin
gyrA 9421 p.Ile707Thr missense_variant 0.18 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
gyrA 9476 c.2175G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>T synonymous_variant 0.29 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>A synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9604 p.Val768Ala missense_variant 0.39 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9626 c.2325T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>A synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9630 p.Val777Ile missense_variant 0.45 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9704 c.2403T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9707 c.2406G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9722 c.2421C>T synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>T synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>A synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9761 c.2460A>G synonymous_variant 0.3 levofloxacin
moxifloxacin
fgd1 490797 c.15G>A synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 490800 c.18A>T synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 490803 c.21T>A synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>T synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 490818 c.36C>T synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fgd1 490830 c.48A>C synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fgd1 490851 c.69A>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fgd1 490854 c.72C>T synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fgd1 490857 c.75C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 490869 c.87C>A synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 490896 c.114C>T synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 490902 c.120T>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>G synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 490917 c.135C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 490921 p.Gln47Lys missense_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491058 c.276C>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 0.19 pretomanid
delamanid
clofazimine
fgd1 491067 c.285C>T synonymous_variant 0.2 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fgd1 491077 p.Asn99Asp missense_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fgd1 491097 c.315G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fgd1 491112 c.330G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fgd1 491491 p.Pro237Thr missense_variant 0.2 pretomanid
delamanid
clofazimine
fgd1 491499 c.717G>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 0.21 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fgd1 491538 c.756G>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 491623 p.Ala281Thr missense_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491637 c.855C>A synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fgd1 491640 c.858G>C synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
mshA 575561 p.Met72Val missense_variant 0.24 isoniazid
ethionamide
mshA 575590 c.243T>G synonymous_variant 0.33 isoniazid
ethionamide
mshA 575611 c.264C>T synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575635 c.288A>G synonymous_variant 0.27 isoniazid
ethionamide
mshA 575652 p.Arg102Gln missense_variant 0.19 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575719 c.372C>T synonymous_variant 0.26 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.42 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.48 isoniazid
ethionamide
mshA 575761 c.414C>T synonymous_variant 0.35 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575771 p.Val142Ser missense_variant 0.35 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 0.34 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.33 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 0.34 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 0.41 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.41 isoniazid
ethionamide
mshA 575824 c.477T>A synonymous_variant 0.33 isoniazid
ethionamide
mshA 575851 c.504C>T synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575864 c.517T>C synonymous_variant 0.21 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.3 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.31 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.34 isoniazid
ethionamide
mshA 575905 c.558G>C synonymous_variant 0.34 isoniazid
ethionamide
mshA 575907 p.Ala187Val missense_variant 0.61 isoniazid Not assoc w R
ethionamide Not assoc w R
mshA 575916 p.Asp190Ala missense_variant 0.43 isoniazid
ethionamide
mshA 575924 p.Gly193Ile missense_variant 0.37 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.29 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.29 isoniazid
ethionamide
mshA 575971 c.624C>T synonymous_variant 0.26 isoniazid
ethionamide
mshA 575980 c.633T>C synonymous_variant 0.23 isoniazid
ethionamide
mshA 576193 c.846T>C synonymous_variant 0.22 isoniazid
ethionamide
mshA 576202 c.855T>G synonymous_variant 0.2 isoniazid
ethionamide
mshA 576205 c.858G>A synonymous_variant 0.19 isoniazid
ethionamide
mshA 576220 c.873C>G synonymous_variant 0.21 isoniazid
ethionamide
mshA 576235 p.Ile296Met missense_variant 0.21 isoniazid
ethionamide
mshA 576247 c.900A>C synonymous_variant 0.27 isoniazid
ethionamide
mshA 576403 c.1056C>G synonymous_variant 0.19 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 619531 c.-360T>C upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619535 c.-356_-354delCAAinsGAG upstream_gene_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 619540 c.-351C>G upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 619615 c.-276C>T upstream_gene_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 619627 c.-264C>T upstream_gene_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>G upstream_gene_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 619647 c.-244T>C upstream_gene_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 619669 c.-222G>C upstream_gene_variant 0.49 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>G upstream_gene_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 619681 c.-210G>C upstream_gene_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 619697 c.-194A>C upstream_gene_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620256 c.366C>G synonymous_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>T synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 620325 c.435G>T synonymous_variant 0.17 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>G synonymous_variant 0.27 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>T synonymous_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.37 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620445 c.555A>G synonymous_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 0.26 kanamycin
capreomycin
amikacin
ccsA 620613 c.723C>T synonymous_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 620622 c.732G>C synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620625 p.Ile245Met missense_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
ccsA 620631 c.741T>G synonymous_variant 0.19 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>T synonymous_variant 0.21 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620685 c.795G>A synonymous_variant 0.24 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
ccsA 620710 p.Val274Ile missense_variant 0.25 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.24 kanamycin
capreomycin
amikacin
ccsA 620727 c.837G>T synonymous_variant 0.2 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>C synonymous_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 620766 c.876C>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620773 p.Ile295Val missense_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620781 c.891C>G synonymous_variant 0.29 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>T synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620809 c.919C>T synonymous_variant 0.31 kanamycin
capreomycin
amikacin
ccsA 620829 c.939G>C synonymous_variant 0.23 kanamycin
capreomycin
amikacin
ccsA 620835 c.945C>G synonymous_variant 0.19 kanamycin
capreomycin
amikacin
Rv0565c 657081 c.390G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657142 p.Arg110His missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.23 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsATT upstream_gene_variant 0.43 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.45 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGC upstream_gene_variant 0.3 ethionamide
Rv0565c 657686 c.-216C>A upstream_gene_variant 0.3 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.33 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.55 ethionamide
hadA 731711 c.-219T>C upstream_gene_variant 0.27 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.23 isoniazid
hadA 731738 c.-192G>T upstream_gene_variant 0.24 isoniazid
hadA 731753 c.-177A>T upstream_gene_variant 0.47 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.42 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.67 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.45 isoniazid
hadA 731795 c.-135C>T upstream_gene_variant 0.2 isoniazid
hadA 731798 c.-132C>G upstream_gene_variant 0.45 isoniazid
hadA 731825 c.-105G>C upstream_gene_variant 0.33 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.38 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.25 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.34 isoniazid
hadA 731861 c.-69G>A upstream_gene_variant 0.18 isoniazid
hadA 732247 c.318C>T synonymous_variant 0.2 isoniazid
hadA 732250 c.321C>G synonymous_variant 0.19 isoniazid
hadA 732263 p.Val112Met missense_variant 0.23 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.33 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.28 isoniazid
hadA 732322 p.Glu131Asp missense_variant 0.31 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.33 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.36 isoniazid
hadA 732358 c.429G>A synonymous_variant 0.23 isoniazid
hadA 732361 c.432C>T synonymous_variant 0.45 isoniazid
hadA 732370 c.441C>T synonymous_variant 0.24 isoniazid
hadA 732374 p.Asp149Asn missense_variant 0.25 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.26 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.29 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.26 isoniazid
nusG 734093 c.-161A>G upstream_gene_variant 0.27 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.26 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.29 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.24 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.31 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.24 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.23 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 0.3 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.23 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 0.22 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.21 rifampicin
nusG 734361 c.108C>T synonymous_variant 0.19 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.24 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.25 rifampicin
nusG 734407 p.Val52Ile missense_variant 0.44 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.42 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.29 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.25 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.25 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.25 rifampicin
nusG 734457 c.204C>T synonymous_variant 0.25 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.28 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>T synonymous_variant 0.25 rifampicin
nusG 734505 c.252G>A synonymous_variant 0.27 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.51 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.29 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.45 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.43 rifampicin
nusG 734616 c.363C>A synonymous_variant 0.26 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.28 rifampicin
nusG 734631 c.378G>A synonymous_variant 0.23 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.24 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.27 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.24 rifampicin
nusG 734661 c.408A>C synonymous_variant 0.28 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.3 rifampicin
nusG 734670 c.417G>A synonymous_variant 0.3 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.32 rifampicin
nusG 734680 p.Ala143Ser missense_variant 0.34 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.28 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.39 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.35 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.36 rifampicin
nusG 734769 c.516G>A synonymous_variant 0.36 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.5 rifampicin
nusG 734784 c.531G>A synonymous_variant 0.53 rifampicin
nusG 734787 c.534T>C synonymous_variant 0.22 rifampicin
nusG 734790 c.537G>C synonymous_variant 0.32 rifampicin
nusG 734793 c.540C>T synonymous_variant 0.33 rifampicin
nusG 734826 c.573A>G synonymous_variant 0.47 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
nusG 734847 c.594T>C synonymous_variant 0.54 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.34 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.33 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.36 rifampicin
nusG 734874 c.621G>A synonymous_variant 0.19 rifampicin
nusG 734880 c.627C>T synonymous_variant 0.2 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.48 rifampicin
nusG 734905 c.652C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
nusG 734910 c.657C>G synonymous_variant 0.28 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.31 rifampicin
mmaA3 737358 c.792A>C synonymous_variant 0.23 isoniazid
mmaA3 737365 p.Ala262Glu missense_variant 0.19 isoniazid
mmaA3 738339 c.-190G>C upstream_gene_variant 0.23 isoniazid
mmaA3 738346 c.-198_-197delCTinsGC upstream_gene_variant 0.33 isoniazid
rpoB 759647 c.-160T>C upstream_gene_variant 0.29 rifampicin Uncertain significance
rpoB 760088 c.282C>G synonymous_variant 0.24 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.46 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.3 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.41 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.2 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.34 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 0.47 rifampicin
rpoB 760307 c.501T>C synonymous_variant 0.62 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.47 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.64 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760356 p.Thr184Ser missense_variant 0.45 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.45 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.45 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.43 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 760415 c.609C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.3 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.34 rifampicin Uncertain significance
rpoB 760533 p.Val243His missense_variant 0.42 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760556 c.750G>A synonymous_variant 0.39 rifampicin
rpoB 760563 p.Arg253Met missense_variant 0.54 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.62 rifampicin
rpoB 760598 c.792C>T synonymous_variant 0.45 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.53 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.43 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.41 rifampicin
rpoB 760754 c.948G>C synonymous_variant 0.43 rifampicin
rpoB 760755 p.His317Asn missense_variant 0.43 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.43 rifampicin
rpoB 760763 c.957C>T synonymous_variant 0.42 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.42 rifampicin
rpoB 760796 c.990A>G synonymous_variant 0.32 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.25 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.28 rifampicin
rpoB 760841 c.1035T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>T synonymous_variant 0.21 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.21 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.31 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.23 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.22 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>T synonymous_variant 0.22 rifampicin
rpoB 760970 c.1164G>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoB 760971 c.1165C>A synonymous_variant 0.24 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.25 rifampicin
rpoB 760985 c.1179G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.31 rifampicin
rpoB 760994 c.1188G>A synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.25 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.48 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.51 rifampicin
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.42 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>A synonymous_variant 0.31 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 0.5 rifampicin
rpoB 761180 c.1374A>G synonymous_variant 0.45 rifampicin
rpoB 761183 c.1377T>G synonymous_variant 0.21 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>G synonymous_variant 0.34 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 761201 c.1395G>A synonymous_variant 0.23 rifampicin
rpoB 761204 c.1398C>T synonymous_variant 0.51 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 0.63 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 0.44 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.49 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.48 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 0.41 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.4 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.54 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.56 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.56 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.44 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.54 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.34 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.35 rifampicin
rpoB 761465 c.1659G>T synonymous_variant 0.38 rifampicin
rpoB 761471 c.1665C>T synonymous_variant 0.42 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 0.33 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.49 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.48 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.45 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 0.39 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.47 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>T synonymous_variant 0.48 rifampicin
rpoB 761561 c.1755C>G synonymous_variant 0.56 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761582 c.1776G>A synonymous_variant 0.5 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.54 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.47 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761666 c.1860G>C synonymous_variant 0.36 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.34 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.42 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.37 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.33 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.31 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.27 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.25 rifampicin
rpoB 761786 c.1980C>A synonymous_variant 0.22 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.25 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.39 rifampicin
rpoB 761819 c.2013G>A synonymous_variant 0.36 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.38 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.37 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.41 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.4 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>A synonymous_variant 0.46 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.46 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.51 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.48 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.44 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.47 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.47 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.47 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.41 rifampicin
rpoB 761933 c.2127G>C synonymous_variant 0.43 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761955 p.Ile717Val missense_variant 0.38 rifampicin Uncertain significance
rpoB 761969 c.2163G>A synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.48 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.5 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762050 c.2244G>A synonymous_variant 0.45 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.54 rifampicin Uncertain significance
rpoB 762138 c.2332C>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.41 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762179 c.2373C>T synonymous_variant 0.38 rifampicin
rpoB 762185 c.2379G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.25 rifampicin
rpoB 762224 c.2418C>G synonymous_variant 0.25 rifampicin
rpoB 762236 c.2430G>A synonymous_variant 0.26 rifampicin
rpoB 762239 c.2433G>A synonymous_variant 0.42 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.68 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.67 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 0.49 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762347 c.2541T>C synonymous_variant 0.53 rifampicin
rpoB 762350 c.2544C>G synonymous_variant 0.41 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.52 rifampicin
rpoB 762368 c.2562G>A synonymous_variant 0.38 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.47 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.5 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.5 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.52 rifampicin
rpoC 762401 c.-969G>T upstream_gene_variant 0.49 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.55 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 762443 c.-927G>C upstream_gene_variant 0.39 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762507 p.Leu901Met missense_variant 0.42 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.56 rifampicin Uncertain significance
rpoC 762524 c.-846G>C upstream_gene_variant 0.41 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.52 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.52 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.52 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.49 rifampicin
rpoC 762563 c.-807G>C upstream_gene_variant 0.27 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 0.22 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762788 c.2982G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.24 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.26 rifampicin
rpoB 762795 p.Asp997Asn missense_variant 0.26 rifampicin Uncertain significance
rpoC 762800 c.-570C>A upstream_gene_variant 0.26 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762814 p.Met1003Arg missense_variant 0.25 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 762824 c.-546C>T upstream_gene_variant 0.27 rifampicin
rpoC 762827 c.-543G>T upstream_gene_variant 0.36 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 762920 c.-450C>G upstream_gene_variant 0.42 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>A upstream_gene_variant 0.5 rifampicin
rpoB 762989 c.3183G>A synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>T upstream_gene_variant 0.2 rifampicin
rpoC 763082 c.-288C>G upstream_gene_variant 0.47 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>A upstream_gene_variant 0.44 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.4 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 0.49 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.6 rifampicin
rpoC 763193 c.-177C>T upstream_gene_variant 0.5 rifampicin
rpoC 763199 c.-171G>T upstream_gene_variant 0.45 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.51 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.49 rifampicin
rpoC 763211 c.-159C>T upstream_gene_variant 0.47 rifampicin
rpoC 763235 c.-135A>G upstream_gene_variant 0.37 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763247 c.-123G>A upstream_gene_variant 0.31 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 0.24 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.26 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.67 rifampicin
rpoC 763423 c.54G>A synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 0.56 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>A synonymous_variant 0.38 rifampicin
rpoC 763573 c.204G>T synonymous_variant 0.39 rifampicin
rpoC 763594 c.225C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>A synonymous_variant 0.4 rifampicin
rpoC 763618 c.249C>T synonymous_variant 0.43 rifampicin
rpoC 763621 c.252C>G synonymous_variant 0.4 rifampicin
rpoC 763636 c.267T>G synonymous_variant 0.43 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763681 c.312C>A synonymous_variant 0.4 rifampicin
rpoC 763702 c.333C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.34 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.4 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.5 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.41 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.49 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.44 rifampicin
rpoC 763768 c.399C>T synonymous_variant 0.35 rifampicin
rpoC 763781 p.Ser138Ala missense_variant 0.41 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.39 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.42 rifampicin
rpoC 763836 p.Ala156Val missense_variant 0.45 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.44 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.43 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.47 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.43 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.44 rifampicin
rpoC 763888 c.519G>T synonymous_variant 0.44 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.45 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.34 rifampicin
rpoC 763936 c.567C>G synonymous_variant 0.32 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.34 rifampicin
rpoC 763969 c.600C>T synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.32 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.42 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.41 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.29 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764024 c.655T>C synonymous_variant 0.48 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.41 rifampicin
rpoC 764044 c.675T>G synonymous_variant 0.45 rifampicin
rpoC 764056 c.687G>T synonymous_variant 0.51 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.59 rifampicin
rpoC 764080 c.711C>T synonymous_variant 0.48 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.65 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>G synonymous_variant 0.5 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 0.31 rifampicin
rpoC 764195 p.Ser276Ile missense_variant 0.28 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.38 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.41 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>A synonymous_variant 0.53 rifampicin
rpoC 764260 c.891G>A synonymous_variant 0.46 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.5 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.67 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.58 rifampicin
rpoC 764339 c.970C>T synonymous_variant 0.6 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764428 c.1059G>T synonymous_variant 0.35 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.39 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.38 rifampicin
rpoC 764452 c.1083T>G synonymous_variant 0.28 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 0.28 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.42 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.43 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.46 rifampicin
rpoC 764554 c.1185C>T synonymous_variant 0.46 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.41 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.46 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.58 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 0.6 rifampicin
rpoC 764857 c.1488G>T synonymous_variant 0.36 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.41 rifampicin
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 0.44 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 0.28 rifampicin
rpoC 764908 c.1539G>A synonymous_variant 0.22 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.22 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>T synonymous_variant 0.21 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.33 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.32 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 0.31 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.34 rifampicin
rpoC 765103 c.1734G>A synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 765106 c.1737G>C synonymous_variant 0.2 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 0.29 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.3 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 0.31 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 0.36 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 0.37 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.44 rifampicin Uncertain significance
rpoC 765404 c.2035C>T synonymous_variant 0.44 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.55 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.44 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>T synonymous_variant 0.42 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>A synonymous_variant 0.46 rifampicin
rpoC 765529 c.2160C>T synonymous_variant 0.44 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.53 rifampicin
rpoC 765547 c.2178C>A synonymous_variant 0.6 rifampicin
rpoC 765556 c.2187G>C synonymous_variant 0.61 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.62 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.47 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.59 rifampicin
rpoC 765592 c.2223C>T synonymous_variant 0.44 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.51 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765676 c.2307G>A synonymous_variant 0.2 rifampicin
rpoC 765685 c.2316G>A synonymous_variant 0.43 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 0.49 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.46 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.5 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.55 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.53 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.58 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.58 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.58 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.57 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.55 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.54 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 765907 c.2538G>A synonymous_variant 0.45 rifampicin
rpoC 765928 c.2559C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.48 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>G synonymous_variant 0.35 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>T synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>A synonymous_variant 0.35 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.24 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.35 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.25 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.26 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.19 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.3 rifampicin
rpoC 766096 c.2727G>T synonymous_variant 0.28 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.34 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.38 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.32 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 0.33 rifampicin Uncertain significance
rpoC 766178 p.Ile937Val missense_variant 0.32 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.27 rifampicin
rpoC 766192 c.2823T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 766193 p.Gln942Glu missense_variant 0.19 rifampicin
rpoC 766255 c.2886G>C synonymous_variant 0.26 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.35 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.41 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.46 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 0.41 rifampicin
rpoC 766294 c.2925C>T synonymous_variant 0.4 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.48 rifampicin
rpoC 766333 c.2964G>C synonymous_variant 0.39 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.41 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.38 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.37 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.33 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.55 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.54 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.4 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.43 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.55 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.43 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.49 rifampicin
rpoC 766492 c.3123T>A synonymous_variant 0.51 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.47 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.49 rifampicin
rpoC 766540 c.3171C>T synonymous_variant 0.51 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.59 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.56 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 0.58 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.64 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.67 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.67 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.68 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.6 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 0.46 rifampicin
rpoC 766666 c.3297C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 0.61 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.19 rifampicin
rpoC 766684 c.3315C>G synonymous_variant 0.21 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.23 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.19 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.74 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.57 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.63 rifampicin
rpoC 766801 c.3432C>A synonymous_variant 0.49 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.42 rifampicin
rpoC 766879 c.3510G>C synonymous_variant 0.22 rifampicin
rpoC 766882 c.3513C>T synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.22 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.28 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.28 rifampicin
rpoC 766900 c.3531T>G synonymous_variant 0.23 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.31 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 0.29 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 766954 c.3585C>T synonymous_variant 0.35 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.45 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 0.42 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.51 rifampicin
rpoC 767044 c.3675G>A synonymous_variant 0.43 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.55 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.31 rifampicin
rpoC 767152 c.3783T>G synonymous_variant 0.33 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 0.35 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.58 rifampicin
rpoC 767185 c.3816G>T synonymous_variant 0.58 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.62 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.36 rifampicin
rpoC 767275 c.3906T>A synonymous_variant 0.29 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.29 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.28 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775909 p.Leu858Phe missense_variant 0.24 bedaquiline
clofazimine
mmpL5 775915 p.Ala856Ser missense_variant 0.2 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.37 bedaquiline
clofazimine
mmpL5 776030 c.2451G>A synonymous_variant 0.27 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776182 p.Asp767Asn missense_variant 1.0 bedaquiline Not assoc w R
clofazimine Not assoc w R
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0 bedaquiline
clofazimine
rpsL 781301 c.-259C>T upstream_gene_variant 1.0 streptomycin
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781571 c.12C>T synonymous_variant 0.29 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.34 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.33 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 0.41 streptomycin
rpsL 781622 c.63C>G synonymous_variant 0.36 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.47 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.48 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.48 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.33 streptomycin
rpsL 781703 c.144G>A synonymous_variant 0.43 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.57 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.55 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.46 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.57 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.44 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.42 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.41 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.56 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.36 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.38 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.54 streptomycin
rpsL 781820 c.261G>T synonymous_variant 0.37 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.61 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.63 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.65 streptomycin
rpsL 781886 c.327C>T synonymous_variant 0.42 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.65 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.67 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.68 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.66 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.45 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 0.29 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.44 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.59 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.54 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.56 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.66 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.64 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.48 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.62 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.47 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.55 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.47 linezolid
rplC 800715 c.-94_-92delATCinsCTT upstream_gene_variant 0.47 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.49 linezolid
rplC 800744 c.-65G>A upstream_gene_variant 0.27 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.24 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.39 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.21 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.46 linezolid
rplC 800783 c.-26C>T upstream_gene_variant 0.29 linezolid
rplC 800797 c.-12T>G upstream_gene_variant 0.26 linezolid
rplC 800799 c.-10G>C upstream_gene_variant 0.26 linezolid
rplC 800800 c.-9G>T upstream_gene_variant 0.26 linezolid
rplC 800801 c.-8A>G upstream_gene_variant 0.26 linezolid
rplC 800817 c.9A>C synonymous_variant 0.3 linezolid
rplC 800844 c.36T>C synonymous_variant 0.38 linezolid
rplC 800865 c.57A>G synonymous_variant 0.31 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.31 linezolid
rplC 800877 c.69A>C synonymous_variant 0.3 linezolid
rplC 800907 c.99C>G synonymous_variant 0.32 linezolid
rplC 800913 c.105G>C synonymous_variant 0.29 linezolid
rplC 800916 c.108A>T synonymous_variant 0.32 linezolid
rplC 800922 c.114C>G synonymous_variant 0.33 linezolid
rplC 800934 c.126C>G synonymous_variant 0.3 linezolid
rplC 800937 c.129A>G synonymous_variant 0.21 linezolid
rplC 800946 c.138T>G synonymous_variant 0.22 linezolid
rplC 800949 c.141T>C synonymous_variant 0.26 linezolid
rplC 800955 c.147C>G synonymous_variant 0.2 linezolid
rplC 800958 c.150G>A synonymous_variant 0.19 linezolid
rplC 800970 c.162T>C synonymous_variant 0.28 linezolid Not assoc w R - Interim
rplC 800976 c.168G>A synonymous_variant 0.28 linezolid
rplC 801171 c.363A>G synonymous_variant 0.35 linezolid
rplC 801174 c.366T>C synonymous_variant 0.53 linezolid
rplC 801195 c.387G>C synonymous_variant 0.4 linezolid
rplC 801207 c.399C>T synonymous_variant 0.42 linezolid
rplC 801210 c.402T>C synonymous_variant 0.62 linezolid
rplC 801219 c.411C>G synonymous_variant 0.56 linezolid
rplC 801222 c.414T>C synonymous_variant 0.66 linezolid
rplC 801228 c.420T>C synonymous_variant 0.43 linezolid
rplC 801246 c.438C>T synonymous_variant 0.48 linezolid
rplC 801252 c.444G>C synonymous_variant 0.27 linezolid
rplC 801255 c.447C>T synonymous_variant 0.32 linezolid
rplC 801267 c.459A>T synonymous_variant 0.48 linezolid
rplC 801309 c.501C>G synonymous_variant 0.32 linezolid
rplC 801312 c.504G>C synonymous_variant 0.61 linezolid
rplC 801321 c.513C>T synonymous_variant 0.29 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.29 linezolid
rplC 801339 c.531T>G synonymous_variant 0.53 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.53 linezolid
rplC 801348 c.540T>G synonymous_variant 0.55 linezolid
rplC 801349 p.Leu181Val missense_variant 0.31 linezolid
rplC 801357 c.549T>C synonymous_variant 0.56 linezolid
rplC 801378 c.570C>T synonymous_variant 0.39 linezolid
rplC 801402 c.594T>C synonymous_variant 0.25 linezolid
rplC 801405 c.597T>C synonymous_variant 0.31 linezolid
Rv1129c 1254562 c.-28T>C upstream_gene_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
rifampicin Not assoc w R
fbiC 1302818 c.-113G>C upstream_gene_variant 0.96 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiC 1303464 c.534A>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1303480 p.Gln184Glu missense_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303492 c.562T>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1303506 c.576C>T synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303537 p.Arg203Leu missense_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303542 c.612C>G synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303593 c.663G>A synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303596 c.666G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>A synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1303716 c.786C>T synonymous_variant 0.19 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>G synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1303750 c.820_822delTTAinsCTG synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1303755 c.825T>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1303779 c.849G>A synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1304142 c.1212G>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1304172 c.1242G>T synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304174 p.Val415Ala missense_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1304574 c.1644C>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304619 c.1689G>T synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>T synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.34 pretomanid
delamanid
clofazimine
fbiC 1304649 c.1719C>T synonymous_variant 0.18 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1304727 c.1797A>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1304754 c.1824G>A synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304796 c.1866G>A synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304799 c.1869G>C synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304823 c.1893C>T synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.54 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304896 c.1966C>T synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304915 p.Asp662Gly missense_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1304970 c.2040G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1304988 c.2058G>C synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 0.25 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 0.2 pretomanid
delamanid
clofazimine
fbiC 1305096 c.2166T>C synonymous_variant 0.21 pretomanid
delamanid
clofazimine
fbiC 1305099 c.2169T>C synonymous_variant 0.23 pretomanid
delamanid
clofazimine
fbiC 1305117 c.2187T>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1305120 c.2190G>A synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 0.36 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305150 c.2220C>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1305154 c.2224T>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1305159 c.2229G>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1305162 c.2232C>T synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1305165 c.2235G>C synonymous_variant 0.26 pretomanid
delamanid
clofazimine
fbiC 1305186 c.2256C>T synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1305192 c.2262C>G synonymous_variant 0.24 pretomanid
delamanid
clofazimine
fbiC 1305195 c.2265T>G synonymous_variant 0.22 pretomanid
delamanid
clofazimine
fbiC 1305215 p.Ser762Thr missense_variant 0.22 pretomanid
delamanid
clofazimine
sigE 1364676 c.264C>G synonymous_variant 0.19 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.19 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.21 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.21 pyrazinamide
sigE 1364727 c.315C>T synonymous_variant 0.21 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.21 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.21 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
sigE 1364760 c.348C>A synonymous_variant 0.18 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
sigE 1364910 c.498G>C synonymous_variant 0.35 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.37 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.44 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.32 pyrazinamide
sigE 1364931 c.519C>G synonymous_variant 0.34 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.36 pyrazinamide
sigE 1364955 c.543G>C synonymous_variant 0.42 pyrazinamide
sigE 1364964 c.552T>C synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.33 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 0.4 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.39 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.31 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.34 pyrazinamide
sigE 1365030 c.618C>T synonymous_variant 0.31 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.31 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.31 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.32 pyrazinamide
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0 streptomycin Uncertain significance
pyrazinamide Uncertain significance
isoniazid Uncertain significance
embR 1416313 c.1035A>C synonymous_variant 0.24 ethambutol
embR 1416316 c.1032C>G synonymous_variant 0.24 ethambutol
embR 1416330 p.Val340Ile missense_variant 0.32 ethambutol
embR 1416335 p.Asn338Ser missense_variant 0.33 ethambutol
embR 1416343 c.1005G>C synonymous_variant 0.33 ethambutol
embR 1416364 c.984C>T synonymous_variant 0.38 ethambutol
embR 1416373 c.975C>G synonymous_variant 0.39 ethambutol
embR 1416376 c.972C>T synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embR 1416386 p.Asp321Ala missense_variant 0.36 ethambutol
embR 1416388 c.960A>G synonymous_variant 0.36 ethambutol
atpE 1461131 c.87T>C synonymous_variant 0.23 bedaquiline
atpE 1461167 c.123G>T synonymous_variant 0.22 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.22 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.19 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.27 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.22 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.33 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.33 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471935 n.90T>C non_coding_transcript_exon_variant 0.22 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185_188delGGGA non_coding_transcript_exon_variant 0.25 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.23 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.46 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.48 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.3 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.46 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.2 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.18 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.19 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.19 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.2 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.51 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.32 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.32 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.52 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473415 n.-243G>A upstream_gene_variant 0.27 capreomycin
linezolid
rrl 1473417 n.-241C>T upstream_gene_variant 0.4 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 0.28 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.4 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.35 capreomycin
linezolid
rrl 1473449 n.-209G>A upstream_gene_variant 0.24 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1473987 n.330G>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.42 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474002 n.345G>A non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1474007 n.350A>G non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.66 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474156 n.499G>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474286 n.629C>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474292 n.635_654delTTCCTCTCCGGAGGAGGGTGinsGTGGA non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474409 n.756_774delACCCACACGCGCATACGCG non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1474433 n.776G>T non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1474435 n.779_783delTGAAT non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.23 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.19 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475446 n.1789G>C non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.22 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.22 capreomycin
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.23 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.25 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475759 n.2102_2106delCCCGCinsTCGT non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.56 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.43 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1476104 n.2448delG non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476301 n.2644A>G non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1476595 n.2938C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1476602 n.2945G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.55 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.38 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.33 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.27 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 0.27 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.34 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.24 capreomycin
linezolid
inhA 1673523 c.-679G>T upstream_gene_variant 0.2 isoniazid
ethionamide
inhA 1673535 c.-667A>C upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673547 c.-655T>C upstream_gene_variant 0.34 isoniazid
ethionamide
inhA 1673679 c.-523T>G upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1673685 c.-517C>T upstream_gene_variant 0.21 isoniazid
ethionamide
inhA 1673712 c.-490A>C upstream_gene_variant 0.28 isoniazid Uncertain significance
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673916 c.-286A>T upstream_gene_variant 0.3 isoniazid
ethionamide
inhA 1673919 c.-283G>C upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1673925 c.-277C>G upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1673946 c.-256C>A upstream_gene_variant 0.23 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1673960 c.-242_-241delCAinsTC upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1673970 c.-232C>G upstream_gene_variant 0.2 isoniazid
ethionamide
inhA 1673976 c.-226T>C upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673982 c.-220G>C upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1673988 c.-214G>C upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1673991 c.-211C>G upstream_gene_variant 0.25 isoniazid
ethionamide
inhA 1674015 c.-187C>A upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1674033 c.-169T>C upstream_gene_variant 0.26 isoniazid
ethionamide
inhA 1674037 c.-165C>G upstream_gene_variant 0.27 isoniazid
ethionamide
inhA 1674045 c.-157G>A upstream_gene_variant 0.24 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 0.28 isoniazid
ethionamide
inhA 1674060 c.-142A>G upstream_gene_variant 0.29 isoniazid
ethionamide
inhA 1674079 c.-123C>G upstream_gene_variant 0.19 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.3 isoniazid
ethionamide
inhA 1674546 c.345T>C synonymous_variant 0.29 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.24 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.25 isoniazid
ethionamide
inhA 1674774 c.573A>C synonymous_variant 0.33 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 0.36 isoniazid
ethionamide
inhA 1674786 c.585G>C synonymous_variant 0.2 isoniazid
ethionamide
inhA 1674792 c.591G>C synonymous_variant 0.2 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.28 isoniazid
ethionamide
inhA 1674810 c.609C>G synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674813 c.612C>T synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674816 c.615T>C synonymous_variant 0.21 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674819 c.618G>T synonymous_variant 0.21 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.25 isoniazid
ethionamide
inhA 1674840 c.639C>T synonymous_variant 0.23 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674846 p.Ile215Met missense_variant 0.25 isoniazid
ethionamide
inhA 1674852 c.651G>A synonymous_variant 0.31 isoniazid
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.29 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 0.27 isoniazid
ethionamide
inhA 1674882 c.681G>C synonymous_variant 0.24 isoniazid
ethionamide
inhA 1674885 c.684C>T synonymous_variant 0.24 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674900 c.699G>A synonymous_variant 0.34 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.59 isoniazid
ethionamide
inhA 1674927 c.726G>A synonymous_variant 0.48 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674939 c.738G>T synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674942 c.741T>G synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674954 c.753G>C synonymous_variant 0.3 isoniazid
ethionamide
inhA 1674993 c.792G>C synonymous_variant 0.22 isoniazid
ethionamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.3 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.5 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>T synonymous_variant 0.58 pyrazinamide
rpsA 1833593 p.Ser18Thr missense_variant 0.22 pyrazinamide
rpsA 1833604 c.63C>T synonymous_variant 0.22 pyrazinamide
rpsA 1833610 c.69C>A synonymous_variant 0.21 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 0.71 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.7 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.27 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.7 pyrazinamide
rpsA 1833754 c.213G>A synonymous_variant 0.3 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
rpsA 1833782 p.Ser81Thr missense_variant 0.4 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.39 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.36 pyrazinamide
rpsA 1833799 c.258C>A synonymous_variant 0.36 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.65 pyrazinamide
rpsA 1833808 c.267G>T synonymous_variant 0.33 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.31 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 0.34 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.38 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.41 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.68 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.66 pyrazinamide
rpsA 1833850 c.309C>G synonymous_variant 0.21 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.64 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.54 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.51 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.56 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.65 pyrazinamide
rpsA 1833934 c.393C>T synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
rpsA 1833949 c.408T>C synonymous_variant 0.56 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.5 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.65 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.62 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.52 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.61 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 0.62 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.28 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.32 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.32 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.29 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.41 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
rpsA 1834222 c.681T>C synonymous_variant 0.18 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.34 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834252 c.711C>T synonymous_variant 0.29 pyrazinamide
rpsA 1834255 c.714C>G synonymous_variant 0.29 pyrazinamide
rpsA 1834258 c.717G>A synonymous_variant 0.29 pyrazinamide
rpsA 1834259 c.718_720delCTAinsTTG synonymous_variant 0.28 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 0.33 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.31 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.44 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.41 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.4 pyrazinamide
rpsA 1834414 c.873C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.42 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 0.23 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.22 pyrazinamide
rpsA 1834444 c.903C>G synonymous_variant 0.23 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.39 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.22 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.42 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.23 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.46 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 0.46 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.26 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.35 pyrazinamide
rpsA 1834517 c.976C>T synonymous_variant 0.35 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.37 pyrazinamide
rpsA 1834556 p.Ala339Thr missense_variant 0.35 pyrazinamide Uncertain significance
rpsA 1834609 c.1068T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
rpsA 1834615 c.1074C>T synonymous_variant 0.55 pyrazinamide
rpsA 1834624 c.1083G>A synonymous_variant 0.41 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.6 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.51 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.48 pyrazinamide
rpsA 1834669 c.1128G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.56 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.19 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.48 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.29 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.4 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.27 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.39 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.41 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.37 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.39 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.46 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.45 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 0.43 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.44 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.46 linezolid
tsnR 1853468 c.-138C>T upstream_gene_variant 0.47 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.46 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 0.42 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.43 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.38 linezolid
tsnR 1853954 p.Arg117Ser missense_variant 0.2 linezolid
tsnR 1853978 p.Val125Leu missense_variant 0.22 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917965 p.Ala9Val missense_variant 0.26 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.36 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 0.36 capreomycin
tlyA 1917987 c.48G>C synonymous_variant 0.39 capreomycin
tlyA 1917996 c.57A>C synonymous_variant 0.38 capreomycin
tlyA 1918002 p.Gln21His missense_variant 0.25 capreomycin
bacA 2064258 c.471A>G synonymous_variant 0.19 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064264 c.465C>G synonymous_variant 0.23 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064269 c.460A>C synonymous_variant 0.2 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064271 p.Trp153Ser missense_variant 0.81 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
bacA 2064296 c.433T>C synonymous_variant 0.26 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064297 c.432C>T synonymous_variant 0.25 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064312 c.417C>G synonymous_variant 0.22 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101873 c.1170T>C synonymous_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2101888 p.Val385Leu missense_variant 0.29 isoniazid
delamanid
ethionamide
ndh 2101891 p.Pro384Arg missense_variant 0.31 isoniazid Uncertain significance
delamanid Uncertain significance
ethionamide Uncertain significance
ndh 2101899 p.Ile382Val missense_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2101912 c.1131G>A synonymous_variant 0.41 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>G synonymous_variant 0.42 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>C synonymous_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2101960 c.1083A>G synonymous_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2101964 p.Glu360Ala missense_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2101966 c.1077T>A synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2101972 c.1071G>C synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2101980 p.Asn355Asp missense_variant 0.4 isoniazid
delamanid
ethionamide
ndh 2101987 c.1056C>G synonymous_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2101990 c.1053G>C synonymous_variant 0.4 isoniazid
delamanid
ethionamide
ndh 2101999 c.1044G>A synonymous_variant 0.38 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102020 c.1023A>G synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2102023 c.1020G>C synonymous_variant 0.26 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102026 c.1017G>T synonymous_variant 0.24 isoniazid
delamanid
ethionamide
ndh 2102035 c.1008C>G synonymous_variant 0.26 isoniazid
delamanid
ethionamide
ndh 2102047 c.996G>C synonymous_variant 0.21 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102050 c.993T>A synonymous_variant 0.22 isoniazid
delamanid
ethionamide
ndh 2102059 c.984T>A synonymous_variant 0.2 isoniazid
delamanid
ethionamide
ndh 2102671 c.372T>C synonymous_variant 0.23 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102680 c.363T>C synonymous_variant 0.25 isoniazid
delamanid
ethionamide
ndh 2102686 c.357G>C synonymous_variant 0.28 isoniazid
delamanid
ethionamide
ndh 2102718 p.Gln109Glu missense_variant 0.27 isoniazid
delamanid
ethionamide
katG 2154724 p.Arg463Leu missense_variant 1.0 isoniazid Not assoc w R
katG 2155649 p.Tyr155His missense_variant 0.31 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.24 isoniazid
PPE35 2167926 p.Leu896Ser missense_variant 1.0 pyrazinamide Not assoc w R
Rv1979c 2223014 p.Tyr51Asn missense_variant 0.96 bedaquiline Uncertain significance
clofazimine Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517941 c.-174C>G upstream_gene_variant 0.59 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.33 isoniazid
kasA 2517956 c.-159G>A upstream_gene_variant 0.22 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.33 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.5 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.29 isoniazid
kasA 2518010 c.-105C>G upstream_gene_variant 0.24 isoniazid
kasA 2518013 c.-102G>A upstream_gene_variant 0.24 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.44 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.38 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.31 isoniazid
kasA 2518252 c.138C>T synonymous_variant 0.29 isoniazid
kasA 2518279 c.165T>C synonymous_variant 0.37 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.38 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.29 isoniazid
kasA 2518300 c.186T>C synonymous_variant 0.29 isoniazid
kasA 2518312 c.198T>C synonymous_variant 0.27 isoniazid
kasA 2518318 c.204C>G synonymous_variant 0.28 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.29 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.3 isoniazid
kasA 2518492 c.378C>T synonymous_variant 0.35 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.28 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.28 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.29 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.38 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.45 isoniazid
kasA 2518567 c.453G>T synonymous_variant 0.38 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.25 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.33 isoniazid
kasA 2518583 p.Gln157Glu missense_variant 0.22 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.3 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.3 isoniazid
kasA 2518594 c.480C>G synonymous_variant 0.23 isoniazid
kasA 2518597 c.483C>G synonymous_variant 0.22 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.26 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.29 isoniazid
kasA 2518630 c.516G>C synonymous_variant 0.27 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.22 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.31 isoniazid
kasA 2518645 c.531G>A synonymous_variant 0.24 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.27 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.29 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.32 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.46 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.35 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.42 isoniazid
kasA 2518687 p.Asp191Glu missense_variant 0.36 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.49 isoniazid
kasA 2518717 c.603C>G synonymous_variant 0.38 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.51 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.19 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.33 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.47 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.37 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.27 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.48 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.2 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.4 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.31 isoniazid
kasA 2518846 c.732G>C synonymous_variant 0.3 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.45 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.3 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.34 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.5 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.3 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.46 isoniazid
kasA 2518907 c.793T>C synonymous_variant 0.29 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.33 isoniazid
kasA 2518936 c.822C>T synonymous_variant 0.28 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.43 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.41 isoniazid
kasA 2519086 c.972C>T synonymous_variant 0.37 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.38 isoniazid
kasA 2519098 c.984C>T synonymous_variant 0.4 isoniazid
kasA 2519104 c.990T>A synonymous_variant 0.43 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.43 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 0.45 isoniazid
kasA 2519119 c.1005G>C synonymous_variant 0.47 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.43 isoniazid
kasA 2519146 c.1032C>G synonymous_variant 0.43 isoniazid
kasA 2519152 c.1038G>T synonymous_variant 0.43 isoniazid
kasA 2519161 c.1047G>A synonymous_variant 0.43 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.44 isoniazid
kasA 2519188 c.1074G>A synonymous_variant 0.42 isoniazid
kasA 2519197 c.1083G>C synonymous_variant 0.42 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 0.39 isoniazid
kasA 2519206 c.1092C>T synonymous_variant 0.36 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.22 isoniazid
eis 2714846 p.Val163Ile missense_variant 1.0 kanamycin Not assoc w R
amikacin Not assoc w R
folC 2746347 p.Ala418Ser missense_variant 0.31 para-aminosalicylic_acid
folC 2746351 c.1248C>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746366 c.1233G>A synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746401 p.Ser400Ala missense_variant 0.38 para-aminosalicylic_acid
folC 2746409 p.Val397Ala missense_variant 0.36 para-aminosalicylic_acid
folC 2746420 c.1179A>C synonymous_variant 0.41 para-aminosalicylic_acid
folC 2746432 c.1167C>A synonymous_variant 0.39 para-aminosalicylic_acid
folC 2746438 c.1161G>C synonymous_variant 0.36 para-aminosalicylic_acid
folC 2746451 p.Gly383Ala missense_variant 0.17 para-aminosalicylic_acid
folC 2746561 c.1038C>A synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746567 c.1032C>T synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746584 c.1015T>C synonymous_variant 0.43 para-aminosalicylic_acid
folC 2746591 c.1008C>G synonymous_variant 0.43 para-aminosalicylic_acid
folC 2746597 c.1002C>G synonymous_variant 0.44 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746612 c.987C>T synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746621 c.978C>G synonymous_variant 0.46 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 0.47 para-aminosalicylic_acid
folC 2746627 p.Asp324Glu missense_variant 0.53 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 0.53 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.49 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.4 para-aminosalicylic_acid
folC 2746675 p.Ser308Ala missense_variant 0.33 para-aminosalicylic_acid
folC 2746678 c.921T>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746681 c.918C>G synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746684 c.915C>T synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746687 p.Leu304Val missense_variant 0.33 para-aminosalicylic_acid
folC 2746711 c.888A>G synonymous_variant 0.33 para-aminosalicylic_acid
folC 2746714 c.885T>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2746728 c.871T>C synonymous_variant 0.3 para-aminosalicylic_acid
folC 2746732 p.Ile289Met missense_variant 0.23 para-aminosalicylic_acid
folC 2746744 c.855T>G synonymous_variant 0.24 para-aminosalicylic_acid
folC 2746957 c.642G>C synonymous_variant 0.21 para-aminosalicylic_acid
folC 2746960 c.639C>G synonymous_variant 0.23 para-aminosalicylic_acid
folC 2746975 c.624T>C synonymous_variant 0.24 para-aminosalicylic_acid
folC 2746978 p.Ala207Glu missense_variant 0.23 para-aminosalicylic_acid
folC 2746990 p.Asp203Glu missense_variant 0.35 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 0.37 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 0.37 para-aminosalicylic_acid
folC 2747007 p.Ser198Gly missense_variant 0.33 para-aminosalicylic_acid
folC 2747010 p.Ile197Val missense_variant 0.32 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747029 c.570G>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747053 c.546C>T synonymous_variant 0.32 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.33 para-aminosalicylic_acid
folC 2747062 c.537A>G synonymous_variant 0.32 para-aminosalicylic_acid
folC 2747065 c.534C>T synonymous_variant 0.33 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 0.31 para-aminosalicylic_acid
folC 2747080 c.519C>G synonymous_variant 0.28 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.22 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 0.2 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.21 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.22 para-aminosalicylic_acid
Rv2477c 2782885 c.1158G>C synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.22 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782928 p.Thr372Lys missense_variant 0.27 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Not assoc w R
rifampicin Not assoc w R
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783140 c.903C>G synonymous_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 0.24 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.3 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783164 c.879G>A synonymous_variant 0.27 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783167 c.876G>A synonymous_variant 0.29 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783236 c.807G>A synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783242 p.Thr267Gln missense_variant 0.34 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783281 c.762G>T synonymous_variant 0.38 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.3 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.46 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783338 c.705C>T synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 0.53 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Ala missense_variant 0.37 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin
Rv2477c 2783428 c.615C>T synonymous_variant 0.46 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783449 c.594C>G synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.45 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783548 c.495T>A synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.45 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783566 c.477C>T synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.44 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.5 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783650 c.393C>T synonymous_variant 0.43 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783659 c.384A>G synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.52 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.56 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.51 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.6 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.49 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783791 c.252C>T synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783812 c.231G>C synonymous_variant 0.4 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 0.36 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783842 c.201C>T synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.35 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 0.42 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.48 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.55 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>A synonymous_variant 0.41 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.43 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 0.59 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783967 c.76T>C synonymous_variant 0.47 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.45 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.5 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784016 c.27G>A synonymous_variant 0.39 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784414 c.-372A>G upstream_gene_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 0.26 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784435 c.-393C>G upstream_gene_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784438 c.-396G>C upstream_gene_variant 0.24 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 0.28 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 0.33 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784492 c.-450C>G upstream_gene_variant 0.31 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784503 c.-461G>A upstream_gene_variant 0.23 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784510 c.-468C>T upstream_gene_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784513 c.-471C>A upstream_gene_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784516 c.-474C>G upstream_gene_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784519 c.-477G>C upstream_gene_variant 0.2 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784522 c.-480C>A upstream_gene_variant 0.19 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784525 c.-483G>T upstream_gene_variant 0.21 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
pepQ 2859431 c.988T>C synonymous_variant 0.24 bedaquiline
clofazimine
pepQ 2859438 c.981T>C synonymous_variant 0.23 bedaquiline
clofazimine
pepQ 2859468 c.951G>T synonymous_variant 0.27 bedaquiline
clofazimine
pepQ 2859489 p.Val310Ala missense_variant 0.31 bedaquiline
clofazimine
pepQ 2859510 c.909T>C synonymous_variant 0.31 bedaquiline
clofazimine
pepQ 2859528 c.891T>C synonymous_variant 0.25 bedaquiline
clofazimine
pepQ 2859732 c.687C>T synonymous_variant 0.24 bedaquiline
clofazimine
pepQ 2859735 c.684G>T synonymous_variant 0.23 bedaquiline
clofazimine
pepQ 2859747 c.672C>G synonymous_variant 0.26 bedaquiline
clofazimine
pepQ 2859765 c.654G>C synonymous_variant 0.32 bedaquiline
clofazimine
pepQ 2859778 p.Val214Asp missense_variant 0.26 bedaquiline
clofazimine
pepQ 2859780 p.Gln213Ala missense_variant 0.26 bedaquiline
clofazimine
pepQ 2859783 c.636G>C synonymous_variant 0.24 bedaquiline
clofazimine
pepQ 2859786 c.633G>C synonymous_variant 0.25 bedaquiline
clofazimine
pepQ 2859825 p.Ala198Ser missense_variant 0.29 bedaquiline
clofazimine
pepQ 2859828 c.591G>A synonymous_variant 0.25 bedaquiline
clofazimine
pepQ 2859834 c.585T>C synonymous_variant 0.23 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
pepQ 2859843 c.576G>C synonymous_variant 0.23 bedaquiline
clofazimine
pepQ 2859852 c.567A>G synonymous_variant 0.2 bedaquiline
clofazimine
Rv2681 2996906 c.168A>G synonymous_variant 0.19 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 0.28 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 0.28 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 0.28 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 0.28 capreomycin
Rv2681 2996981 c.243C>A synonymous_variant 0.29 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 0.3 capreomycin
Rv2752c 3064539 c.1653T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064566 c.1626G>C synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064578 c.1614C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064584 c.1608G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064590 c.1602C>G synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064593 c.1599G>A synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3064596 c.1596G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064602 c.1590T>G synonymous_variant 0.44 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064617 c.1575T>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064809 c.1383C>T synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064985 c.1207C>T synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064989 c.1203G>C synonymous_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064998 c.1194A>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065016 c.1176C>T synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065022 c.1170G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065046 c.1146G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065052 c.1140G>A synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065067 c.1125C>T synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065073 c.1119C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065087 c.1105A>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>C synonymous_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065097 c.1095C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065106 c.1086C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065111 c.1081A>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065120 p.Ile358Val missense_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065126 p.Ser356Ala missense_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065130 c.1062A>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065166 c.1026C>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065517 c.675C>G synonymous_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065580 c.612G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065595 p.Leu199Phe missense_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065634 c.558G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065640 c.552T>C synonymous_variant 0.27 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065652 c.540C>A synonymous_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065916 c.276T>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065928 c.264G>C synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065947 p.Gly82Ala missense_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065949 c.243C>T synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065957 c.235T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065958 c.234G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065979 c.213T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 0.39 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066002 p.Met64Leu missense_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066006 c.186G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066018 c.174T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 0.3 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066071 c.121T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066075 c.117A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066084 c.108C>T synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066087 c.105A>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3066118 p.Asn25Gly missense_variant 0.25 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066126 c.66C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066129 c.63G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066135 c.57C>T synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066138 c.54C>G synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066401 c.-210A>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066420 c.-229C>G upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066435 c.-244T>A upstream_gene_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066456 c.-265A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066465 c.-276_-274delGGGinsAGC upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066468 c.-277C>G upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066471 c.-280A>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066474 c.-283G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066480 c.-291_-289delGCCinsTCT upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066504 c.-313C>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066513 c.-322C>G upstream_gene_variant 0.36 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066543 c.-352C>A upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066560 c.-369C>T upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066561 c.-370A>T upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066567 c.-376C>A upstream_gene_variant 0.29 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066582 c.-392_-391delCCinsGT upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066596 c.-405C>T upstream_gene_variant 0.23 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066597 c.-406C>T upstream_gene_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.26 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066636 c.-445G>A upstream_gene_variant 0.2 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.32 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066672 c.-481G>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066676 c.-485C>T upstream_gene_variant 0.22 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067250 c.696G>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067280 c.666G>C synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067284 p.Ala221Asp missense_variant 0.31 para-aminosalicylic_acid
thyX 3067293 p.Gln218Arg missense_variant 0.23 para-aminosalicylic_acid
thyX 3067295 c.651C>A synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067331 c.615C>T synonymous_variant 0.26 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.35 para-aminosalicylic_acid
thyX 3067360 p.Ile196Val missense_variant 0.26 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067382 c.564C>T synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067394 c.552G>T synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067430 c.516C>T synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067445 c.501C>A synonymous_variant 0.31 para-aminosalicylic_acid
thyX 3067451 c.495G>A synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.19 para-aminosalicylic_acid
thyX 3067616 c.330C>G synonymous_variant 0.19 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067634 c.312C>T synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067643 c.303C>T synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067655 c.291G>C synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.32 para-aminosalicylic_acid
thyX 3067670 c.276G>A synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067676 c.270C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067715 p.Ser77Thr missense_variant 0.2 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.25 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067788 p.Lys53Arg missense_variant 0.23 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.24 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 0.2 para-aminosalicylic_acid
thyX 3067823 c.123G>C synonymous_variant 0.21 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.33 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.42 para-aminosalicylic_acid
thyA 3073860 c.612C>T synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.27 para-aminosalicylic_acid
thyA 3073887 p.Ser195Gly missense_variant 0.28 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 0.36 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3073932 c.540C>T synonymous_variant 0.46 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.58 para-aminosalicylic_acid
thyA 3073983 c.489C>T synonymous_variant 0.53 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.54 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.65 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3074046 c.426G>C synonymous_variant 0.55 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.63 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.63 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3074089 p.Ile128Asn missense_variant 0.36 para-aminosalicylic_acid
thyA 3074091 c.381C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074100 p.Asp124Asn missense_variant 0.3 para-aminosalicylic_acid
thyA 3074103 c.369C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074121 p.Asp117Lys missense_variant 0.3 para-aminosalicylic_acid
thyA 3074127 c.345G>T synonymous_variant 0.21 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.52 para-aminosalicylic_acid
thyA 3074133 c.339C>T synonymous_variant 0.48 para-aminosalicylic_acid
thyA 3074151 c.321G>A synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3074160 c.312A>T synonymous_variant 0.27 para-aminosalicylic_acid
thyA 3074163 c.309T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.18 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074184 c.288A>G synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074196 c.276G>C synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3074199 c.273G>A synonymous_variant 0.43 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.44 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 0.4 para-aminosalicylic_acid
thyA 3074220 c.252A>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074244 c.228A>C synonymous_variant 0.24 para-aminosalicylic_acid
thyA 3074252 p.Glu74Gln missense_variant 0.4 para-aminosalicylic_acid
thyA 3074253 p.His73Gln missense_variant 0.24 para-aminosalicylic_acid
thyA 3074256 c.216G>A synonymous_variant 0.41 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.28 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.47 para-aminosalicylic_acid
thyA 3074283 c.189G>A synonymous_variant 0.21 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.45 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 0.29 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087684 p.Ala289Thr missense_variant 0.21 cycloserine
ald 3087696 p.Thr293Ala missense_variant 0.25 cycloserine
ald 3087704 c.885T>C synonymous_variant 0.29 cycloserine
ald 3087716 c.897G>C synonymous_variant 0.23 cycloserine
ald 3087726 p.Ala303Ser missense_variant 0.18 cycloserine
ald 3087729 p.Ser304Ala missense_variant 0.2 cycloserine
Rv3236c 3612628 c.489G>C synonymous_variant 0.35 pyrazinamide
Rv3236c 3612643 c.474A>G synonymous_variant 0.43 pyrazinamide
Rv3236c 3612667 c.450T>C synonymous_variant 0.43 pyrazinamide
Rv3236c 3612673 c.444G>A synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
Rv3236c 3612679 c.438G>C synonymous_variant 0.48 pyrazinamide
Rv3236c 3612685 c.432C>T synonymous_variant 0.43 pyrazinamide
Rv3236c 3612694 p.Arg141His missense_variant 0.45 pyrazinamide Uncertain significance
Rv3236c 3612708 c.409T>C synonymous_variant 0.39 pyrazinamide
Rv3236c 3612712 c.405G>C synonymous_variant 0.34 pyrazinamide
Rv3236c 3612724 c.393T>C synonymous_variant 0.24 pyrazinamide
Rv3236c 3612727 c.390G>C synonymous_variant 0.21 pyrazinamide
Rv3236c 3612733 c.384C>G synonymous_variant 0.21 pyrazinamide
Rv3236c 3612736 c.381T>C synonymous_variant 0.19 pyrazinamide
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0 pyrazinamide Not assoc w R - Interim
lpqB 3624041 p.Glu290Asp missense_variant 0.3 rifampicin
bedaquiline
lpqB 3624071 c.840C>T synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3624080 c.831G>A synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624094 c.817A>C synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3624098 c.813G>A synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3624101 c.810C>A synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624116 c.795A>C synonymous_variant 0.22 rifampicin
bedaquiline
lpqB 3624125 c.786A>G synonymous_variant 0.25 rifampicin
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 0.31 rifampicin
bedaquiline
lpqB 3624406 c.505C>T synonymous_variant 0.3 rifampicin
bedaquiline
lpqB 3624422 c.489G>C synonymous_variant 0.24 rifampicin
bedaquiline
lpqB 3624425 p.Glu162Ala missense_variant 0.23 rifampicin
bedaquiline
lpqB 3624428 c.483A>G synonymous_variant 0.23 rifampicin
bedaquiline
lpqB 3624464 c.447A>G synonymous_variant 0.27 rifampicin
bedaquiline
lpqB 3624467 c.444C>G synonymous_variant 0.24 rifampicin
bedaquiline
lpqB 3624470 c.441T>C synonymous_variant 0.24 rifampicin
bedaquiline
lpqB 3624674 c.237C>T synonymous_variant 0.19 rifampicin
bedaquiline
lpqB 3624686 p.Glu75Gln missense_variant 0.26 rifampicin
bedaquiline
lpqB 3624701 c.210T>A synonymous_variant 0.29 rifampicin
bedaquiline
lpqB 3624713 c.198C>T synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3624722 c.189C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 0.36 rifampicin
bedaquiline
lpqB 3624760 c.151C>T synonymous_variant 0.37 rifampicin
bedaquiline
lpqB 3624776 c.135T>C synonymous_variant 0.39 rifampicin
bedaquiline
lpqB 3624779 c.132G>C synonymous_variant 0.34 rifampicin
bedaquiline
lpqB 3624783 p.Ser43Thr missense_variant 0.34 rifampicin
bedaquiline
lpqB 3624788 c.123A>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625057 c.-147C>T upstream_gene_variant 0.24 rifampicin
bedaquiline
lpqB 3625060 c.-150G>C upstream_gene_variant 0.22 rifampicin
bedaquiline
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3625095 p.Glu507Gln missense_variant 0.3 rifampicin
bedaquiline
lpqB 3625096 c.-186C>T upstream_gene_variant 0.21 rifampicin
bedaquiline
lpqB 3625102 c.-192A>G upstream_gene_variant 0.2 rifampicin
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.22 rifampicin
bedaquiline
lpqB 3625161 c.-251T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625174 c.-264C>A upstream_gene_variant 0.26 rifampicin
bedaquiline
lpqB 3625183 c.-273G>C upstream_gene_variant 0.33 rifampicin
bedaquiline
lpqB 3625186 c.-276T>G upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625218 c.-308C>A upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625240 c.-330T>C upstream_gene_variant 0.23 rifampicin
bedaquiline
lpqB 3625243 c.-333T>C upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625255 c.-345T>G upstream_gene_variant 0.23 rifampicin
bedaquiline
mtrB 3625261 c.1353C>T synonymous_variant 0.18 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625279 c.-369C>G upstream_gene_variant 0.22 rifampicin
bedaquiline
mtrB 3625301 p.Ala438Gly missense_variant 0.23 rifampicin
bedaquiline
lpqB 3625309 c.-399C>T upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625327 c.-417A>G upstream_gene_variant 0.29 rifampicin
bedaquiline
lpqB 3625345 c.-435T>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3625497 c.1117T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625510 c.-600T>G upstream_gene_variant 0.36 rifampicin
bedaquiline
lpqB 3625518 c.-608T>C upstream_gene_variant 0.3 rifampicin
bedaquiline
lpqB 3625522 c.-612C>G upstream_gene_variant 0.28 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 0.43 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.32 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 0.33 rifampicin
bedaquiline
lpqB 3625588 c.-678G>A upstream_gene_variant 0.27 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 0.4 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 0.38 rifampicin
bedaquiline
lpqB 3625612 c.-702G>T upstream_gene_variant 0.28 rifampicin
bedaquiline
lpqB 3625615 c.-705G>C upstream_gene_variant 0.21 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625630 c.-720C>G upstream_gene_variant 0.25 rifampicin
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.39 rifampicin
bedaquiline
lpqB 3625669 c.-759G>A upstream_gene_variant 0.25 rifampicin
bedaquiline
lpqB 3625684 c.-774G>A upstream_gene_variant 0.19 rifampicin
bedaquiline
lpqB 3625693 c.-783G>T upstream_gene_variant 0.38 rifampicin
bedaquiline
mtrB 3625708 c.906C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 0.57 rifampicin Uncertain significance
bedaquiline
mtrB 3625762 c.852A>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625774 c.840G>A synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625792 c.-882G>A upstream_gene_variant 0.32 rifampicin
bedaquiline
lpqB 3625804 c.-896_-894delAGGinsCGA upstream_gene_variant 0.49 rifampicin
bedaquiline
mtrB 3625807 c.807C>G synonymous_variant 0.29 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625822 c.-912C>T upstream_gene_variant 0.53 rifampicin
bedaquiline
lpqB 3625828 c.-918G>A upstream_gene_variant 0.37 rifampicin
bedaquiline
lpqB 3625846 c.-936G>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625860 p.Ala252Ser missense_variant 0.34 rifampicin
bedaquiline
mtrB 3625864 c.750T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625888 c.-978G>C upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrB 3626308 c.306T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626562 p.Pro18Ser missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
mtrB 3626684 c.-71G>T upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrB 3626702 c.-91_-89delCTGinsTTA upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3626750 c.-137T>C upstream_gene_variant 0.28 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626798 c.-185T>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626819 c.-206G>A upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 0.43 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 0.34 rifampicin
bedaquiline
mtrB 3626866 c.-253T>C upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3626885 c.-272A>C upstream_gene_variant 0.35 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 0.29 rifampicin
bedaquiline
mtrA 3626939 c.411A>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 0.37 rifampicin
bedaquiline
mtrB 3626954 c.-341C>G upstream_gene_variant 0.4 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3626969 c.-356C>G upstream_gene_variant 0.3 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3626981 c.-368C>T upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.32 rifampicin
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 0.45 rifampicin
bedaquiline
mtrB 3627113 c.-500C>T upstream_gene_variant 0.33 rifampicin
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrA 3627175 c.175C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3627185 c.-574_-572delTTGinsCTT upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3627188 c.-577_-575delTTAinsCTG upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3627197 c.-584T>C upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>G upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrA 3627242 c.108C>T synonymous_variant 0.45 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 0.21 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.48 rifampicin
bedaquiline
mtrB 3627272 c.-659G>T upstream_gene_variant 0.46 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.26 rifampicin
bedaquiline
mtrB 3627278 c.-665G>T upstream_gene_variant 0.31 rifampicin
bedaquiline
mtrB 3627287 c.-674C>G upstream_gene_variant 0.54 rifampicin
bedaquiline
mtrB 3627296 c.-683T>G upstream_gene_variant 0.43 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTC upstream_gene_variant 0.36 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 0.32 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 0.33 rifampicin
bedaquiline
fbiB 3642656 c.1122G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiB 3642662 c.1128C>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiB 3642668 c.1134A>C synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3642677 c.1143A>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiB 3642680 c.1146A>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiB 3642683 c.1149C>A synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fbiB 3642704 c.1170G>T synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3642707 c.1173C>G synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiB 3642711 p.Leu393Val missense_variant 0.31 pretomanid
delamanid
clofazimine
fbiB 3642719 c.1185T>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiB 3642731 c.1197C>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiB 3642749 c.1215T>C synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiB 3642752 c.1218C>T synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiB 3642763 p.Asp410Ala missense_variant 0.33 pretomanid
delamanid
clofazimine
alr 3840275 c.1146T>G synonymous_variant 0.27 cycloserine
alr 3840296 c.1125G>C synonymous_variant 0.26 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 0.21 rifampicin Uncertain significance
rpoA 3877505 p.Ala335Ser missense_variant 0.21 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.24 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877587 c.921A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.4 rifampicin
rpoA 3877647 c.861C>A synonymous_variant 0.19 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.49 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.3 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 0.5 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 0.37 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 0.2 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.24 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.24 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>G synonymous_variant 0.5 rifampicin
rpoA 3877886 c.622C>T synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.3 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.51 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 0.49 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.51 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.43 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>A synonymous_variant 0.3 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.41 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.39 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.4 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.39 rifampicin
rpoA 3878043 c.465G>C synonymous_variant 0.36 rifampicin
rpoA 3878049 c.459G>C synonymous_variant 0.32 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.33 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.41 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.27 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 0.25 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.24 rifampicin
rpoA 3878079 c.429C>T synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoA 3878082 c.426T>C synonymous_variant 0.25 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.3 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.36 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.33 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.49 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.19 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.32 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoA 3878295 c.213A>G synonymous_variant 0.49 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.26 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoA 3878355 c.153C>G synonymous_variant 0.28 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.31 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoA 3878406 c.102G>T synonymous_variant 0.44 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.34 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 0.36 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.4 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.44 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 0.29 rifampicin
rpoA 3878471 p.Val13Ile missense_variant 0.27 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.44 rifampicin
rpoA 3878490 c.18C>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoA 3878496 c.12A>T synonymous_variant 0.34 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.29 rifampicin
rpoA 3878728 c.-221G>A upstream_gene_variant 0.3 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.44 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.55 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.2 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.59 rifampicin Uncertain significance
rpoA 3878791 c.-284C>T upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.19 rifampicin
rpoA 3878806 c.-299C>G upstream_gene_variant 0.44 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.6 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.59 rifampicin
rpoA 3878837 c.-331_-330delAAinsGG upstream_gene_variant 0.58 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.68 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.69 rifampicin Uncertain significance
rpoA 3878884 c.-377C>G upstream_gene_variant 0.51 rifampicin
rpoA 3878909 c.-402A>G upstream_gene_variant 0.66 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.68 rifampicin Uncertain significance
rpoA 3878938 c.-431T>C upstream_gene_variant 0.64 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.49 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGTG upstream_gene_variant 0.33 rifampicin
rpoA 3878991 c.-484C>A upstream_gene_variant 0.38 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.47 rifampicin Uncertain significance
rpoA 3879006 c.-499A>C upstream_gene_variant 0.42 rifampicin
rpoA 3879013 c.-508_-506delGAAinsAAC upstream_gene_variant 0.24 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.4 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.39 rifampicin
rpoA 3879033 c.-526C>T upstream_gene_variant 0.26 rifampicin
rpoA 3879034 c.-527G>C upstream_gene_variant 0.26 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 0.29 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.34 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.34 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.41 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.43 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.52 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.38 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.53 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.55 rifampicin
rpoA 3879190 c.-683C>T upstream_gene_variant 0.43 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.4 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.39 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.41 rifampicin
rpoA 3879238 c.-731C>G upstream_gene_variant 0.31 rifampicin
ddn 3986615 c.-229C>T upstream_gene_variant 0.33 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.41 pretomanid
delamanid
ddn 3986637 c.-207C>T upstream_gene_variant 0.26 pretomanid
delamanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.27 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.47 pretomanid
delamanid
ddn 3986657 c.-187C>G upstream_gene_variant 0.38 pretomanid
delamanid
ddn 3986663 c.-181G>A upstream_gene_variant 0.23 pretomanid
delamanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.33 pretomanid
delamanid
ddn 3987089 c.246G>C synonymous_variant 0.29 pretomanid
delamanid
ddn 3987092 p.Glu83Asp missense_variant 0.27 pretomanid
delamanid Uncertain significance
ddn 3987098 c.255C>T synonymous_variant 0.24 pretomanid
delamanid
clpC1 4038271 p.Pro812Ala missense_variant 0.3 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 0.26 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.43 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.26 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 0.27 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.36 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.21 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.22 pyrazinamide
clpC1 4038323 c.2382C>G synonymous_variant 0.25 pyrazinamide
clpC1 4038329 p.Glu792Asp missense_variant 0.29 pyrazinamide
clpC1 4038335 c.2370C>T synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4038344 c.2361G>A synonymous_variant 0.23 pyrazinamide Not assoc w R - Interim
clpC1 4038350 c.2355C>G synonymous_variant 0.46 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.44 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.46 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.41 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.21 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.38 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 0.28 pyrazinamide
clpC1 4038436 p.Ala757Ser missense_variant 0.21 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.29 pyrazinamide
clpC1 4038461 c.2244G>T synonymous_variant 0.17 pyrazinamide
clpC1 4038474 p.Ser744Ala missense_variant 0.2 pyrazinamide
clpC1 4038486 p.Gly740Thr missense_variant 0.29 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.42 pyrazinamide
clpC1 4038519 p.Arg729Gln missense_variant 0.58 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.63 pyrazinamide
clpC1 4038536 c.2169C>T synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4038596 c.2109A>G synonymous_variant 0.62 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.25 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.56 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.31 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.24 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.23 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.45 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.45 pyrazinamide
clpC1 4038665 c.2040C>G synonymous_variant 0.21 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.46 pyrazinamide
clpC1 4038674 c.2031C>G synonymous_variant 0.24 pyrazinamide
clpC1 4038677 c.2028G>A synonymous_variant 0.22 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4038686 c.2019C>T synonymous_variant 0.27 pyrazinamide
clpC1 4038692 c.2013C>G synonymous_variant 0.22 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>A synonymous_variant 0.33 pyrazinamide
clpC1 4038698 c.2007C>G synonymous_variant 0.35 pyrazinamide
clpC1 4038701 p.Leu668Phe missense_variant 0.25 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.52 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.23 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.57 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.44 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.23 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.45 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.56 pyrazinamide
clpC1 4038815 c.1890G>A synonymous_variant 0.39 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.31 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.38 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.62 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.62 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.34 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.6 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.54 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.53 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.54 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.55 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 0.59 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.62 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.51 pyrazinamide Not assoc w R - Interim
clpC1 4039021 c.1684C>T synonymous_variant 0.49 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.58 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.4 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.46 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.53 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.55 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.39 pyrazinamide
clpC1 4039140 p.Glu522Val missense_variant 0.39 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.48 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.54 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.58 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.43 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 0.33 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 0.39 pyrazinamide
clpC1 4039268 c.1437C>T synonymous_variant 0.42 pyrazinamide
clpC1 4039274 c.1431G>T synonymous_variant 0.44 pyrazinamide
clpC1 4039277 c.1428C>T synonymous_variant 0.36 pyrazinamide
clpC1 4039283 c.1422C>T synonymous_variant 0.36 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.51 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.52 pyrazinamide
clpC1 4039319 p.Ala462Thr missense_variant 0.48 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 0.45 pyrazinamide
clpC1 4039328 c.1377A>T synonymous_variant 0.42 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.39 pyrazinamide
clpC1 4039355 c.1350G>T synonymous_variant 0.31 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.37 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.37 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.33 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.41 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.57 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.52 pyrazinamide
clpC1 4039493 c.1212C>T synonymous_variant 0.19 pyrazinamide Not assoc w R - Interim
clpC1 4039517 c.1188C>G synonymous_variant 0.54 pyrazinamide
clpC1 4039552 c.1153C>T synonymous_variant 0.33 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.37 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.32 pyrazinamide
clpC1 4039574 p.Ala377Ser missense_variant 0.37 pyrazinamide
clpC1 4039589 c.1116G>T synonymous_variant 0.4 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.57 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.56 pyrazinamide
clpC1 4039622 c.1083C>G synonymous_variant 0.53 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.7 pyrazinamide
clpC1 4039673 c.1032G>C synonymous_variant 0.52 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.6 pyrazinamide
clpC1 4039715 c.990G>A synonymous_variant 0.43 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.54 pyrazinamide
clpC1 4039727 c.978C>T synonymous_variant 0.38 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.35 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.46 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.37 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.45 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.46 pyrazinamide
clpC1 4039796 c.909C>T synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4039817 c.888A>T synonymous_variant 0.46 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.55 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.53 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.34 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.41 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.34 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 0.4 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.39 pyrazinamide
clpC1 4039997 c.708C>T synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.41 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 0.43 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.61 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.29 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.44 pyrazinamide
clpC1 4040138 c.567G>C synonymous_variant 0.29 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>T synonymous_variant 0.23 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.28 pyrazinamide
clpC1 4040180 c.525C>G synonymous_variant 0.29 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.22 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.21 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.21 pyrazinamide
clpC1 4040219 c.486C>T synonymous_variant 0.18 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.2 pyrazinamide
clpC1 4040234 c.471C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.22 pyrazinamide
clpC1 4040243 c.462C>G synonymous_variant 0.3 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.31 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.42 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 0.31 pyrazinamide
clpC1 4040288 c.417C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4040321 c.384C>T synonymous_variant 0.35 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.32 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.3 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.2 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.2 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.18 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.23 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.21 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.2 pyrazinamide Not assoc w R - Interim
clpC1 4040465 c.240T>C synonymous_variant 0.27 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.33 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.28 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.24 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.28 pyrazinamide
clpC1 4040549 c.154_156delTTGinsCTT synonymous_variant 0.26 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.38 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.28 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>T synonymous_variant 0.26 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.29 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.29 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.27 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.34 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.32 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.21 pyrazinamide Not assoc w R - Interim
clpC1 4040711 c.-7G>A upstream_gene_variant 0.27 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 0.27 pyrazinamide Not assoc w R - Interim
panD 4044188 c.94T>C synonymous_variant 0.26 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.38 pyrazinamide
panD 4044201 c.81C>G synonymous_variant 0.24 pyrazinamide
panD 4044231 p.Cys17Gln missense_variant 0.24 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.2 pyrazinamide
glpK 4138370 c.1386C>T synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138377 p.Val460Ala missense_variant 0.24 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
isoniazid Not assoc w R
streptomycin Not assoc w R
rifampicin Not assoc w R
ethambutol Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 0.25 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138382 c.1374A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138385 c.1371A>G synonymous_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138418 c.1338T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138424 c.1332T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138429 c.1327T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138451 c.1305T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138457 p.Asp433Glu missense_variant 0.28 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138472 c.1284G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138478 c.1278T>C synonymous_variant 0.24 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139129 c.627G>A synonymous_variant 0.24 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139132 c.624A>G synonymous_variant 0.34 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139135 c.621T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139143 c.613T>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139159 c.597C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139165 c.591A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139168 c.588T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139183 c.573T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139186 c.570G>C synonymous_variant 0.51 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139193 p.Pro188Val missense_variant 0.48 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139195 c.561G>T synonymous_variant 0.49 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139231 c.525A>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139242 c.514T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139243 c.513A>C synonymous_variant 0.45 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139255 c.501G>A synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139258 c.498C>A synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139261 c.495C>G synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139270 c.486C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139273 c.483A>C synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139276 c.480T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139282 c.474T>C synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139285 c.471A>G synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139633 c.123C>T synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139648 c.108T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139651 p.His35Arg missense_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4239044 c.-819G>C upstream_gene_variant 0.18 ethambutol
embC 4239059 c.-804G>C upstream_gene_variant 0.19 ethambutol
embC 4239089 c.-774C>G upstream_gene_variant 0.24 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 0.41 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 0.4 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 0.42 ethambutol
embC 4239156 c.-707_-706delACinsTT upstream_gene_variant 0.35 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 0.42 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 0.32 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 0.4 ethambutol
embC 4239179 c.-684G>A upstream_gene_variant 0.3 ethambutol
embC 4239189 c.-674C>T upstream_gene_variant 0.36 ethambutol
embC 4239209 c.-654G>C upstream_gene_variant 0.25 ethambutol
embC 4239215 c.-648T>G upstream_gene_variant 0.19 ethambutol
embC 4239305 c.-558G>C upstream_gene_variant 0.32 ethambutol
embC 4239336 c.-527T>C upstream_gene_variant 0.39 ethambutol
embC 4239341 c.-522G>C upstream_gene_variant 0.29 ethambutol
embC 4239378 c.-485T>C upstream_gene_variant 0.49 ethambutol
embC 4239401 c.-462A>C upstream_gene_variant 0.41 ethambutol
embC 4239407 c.-456C>G upstream_gene_variant 0.25 ethambutol
embC 4239411 c.-452_-450delTCCinsGCG upstream_gene_variant 0.24 ethambutol
embC 4239421 c.-442A>T upstream_gene_variant 0.28 ethambutol
embC 4239426 c.-437_-435delCCAinsTCC upstream_gene_variant 0.28 ethambutol
embC 4240459 c.597G>C synonymous_variant 0.34 ethambutol
embC 4240462 c.600G>C synonymous_variant 0.35 ethambutol
embC 4240486 c.624G>A synonymous_variant 0.47 ethambutol
embC 4240489 c.627A>G synonymous_variant 0.48 ethambutol
embC 4240490 p.Pro210Ala missense_variant 0.42 ethambutol Uncertain significance
embC 4240495 c.633T>C synonymous_variant 0.47 ethambutol
embC 4240512 p.Ser217Thr missense_variant 0.45 ethambutol
embC 4240516 c.654G>C synonymous_variant 0.42 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.42 ethambutol
embC 4240561 c.699C>G synonymous_variant 0.25 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.21 ethambutol
embC 4240717 c.855T>C synonymous_variant 0.46 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embC 4240741 c.879C>T synonymous_variant 0.55 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.63 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.52 ethambutol
embC 4240811 p.Phe317Leu missense_variant 0.43 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.45 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.46 ethambutol
embC 4240837 c.975C>G synonymous_variant 0.41 ethambutol
embC 4240859 p.Leu333Ile missense_variant 0.45 ethambutol
embC 4240867 c.1005T>G synonymous_variant 0.41 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.39 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.43 ethambutol
embC 4240885 c.1023T>C synonymous_variant 0.44 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.39 ethambutol Not assoc w R
embC 4240900 c.1038A>G synonymous_variant 0.39 ethambutol
embC 4240918 c.1056G>C synonymous_variant 0.32 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.3 ethambutol
embC 4240927 c.1065C>T synonymous_variant 0.22 ethambutol
embC 4240935 p.Val358Ala missense_variant 0.21 ethambutol Uncertain significance
embC 4240954 c.1092T>C synonymous_variant 0.25 ethambutol
embC 4240957 c.1095C>G synonymous_variant 0.2 ethambutol
embC 4240966 c.1104G>C synonymous_variant 0.23 ethambutol
embC 4241039 p.Asp393Asn missense_variant 0.23 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.42 ethambutol
embC 4241056 c.1194C>G synonymous_variant 0.28 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.21 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.38 ethambutol
embC 4241101 c.1239G>C synonymous_variant 0.41 ethambutol
embC 4241121 p.Ser420Asn missense_variant 0.41 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embC 4241158 c.1296T>C synonymous_variant 0.25 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.43 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.43 ethambutol
embC 4241167 c.1305C>G synonymous_variant 0.2 ethambutol
embC 4241185 c.1323G>C synonymous_variant 0.3 ethambutol
embC 4241197 c.1335G>C synonymous_variant 0.26 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.18 ethambutol
embC 4241545 c.1683T>G synonymous_variant 0.23 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.21 ethambutol
embC 4241551 c.1689A>C synonymous_variant 0.2 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.31 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.33 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.33 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.27 ethambutol
embC 4241617 c.1755G>A synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embC 4241623 c.1761C>A synonymous_variant 0.21 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.21 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.21 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4242791 p.Ala977Ser missense_variant 0.25 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.22 ethambutol
embA 4242805 c.-428G>A upstream_gene_variant 0.26 ethambutol
embA 4242826 c.-407G>C upstream_gene_variant 0.33 ethambutol
embA 4242827 c.-406C>T upstream_gene_variant 0.35 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 0.41 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.51 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.54 ethambutol
embC 4242847 c.2985C>G synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embA 4242853 c.-380C>T upstream_gene_variant 0.52 ethambutol
embC 4242863 p.Tyr1001Asn missense_variant 0.61 ethambutol
embA 4242895 c.-338C>T upstream_gene_variant 0.65 ethambutol
embC 4242904 c.3042C>T synonymous_variant 0.58 ethambutol Not assoc w R - Interim
embA 4242910 c.-323C>T upstream_gene_variant 0.54 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 0.57 ethambutol
embA 4242925 c.-308C>T upstream_gene_variant 0.53 ethambutol
embC 4242928 c.3066A>G synonymous_variant 0.52 ethambutol Not assoc w R - Interim
embA 4242940 c.-293T>C upstream_gene_variant 0.42 ethambutol
embC 4242941 p.His1027Asn missense_variant 0.42 ethambutol
embA 4242946 c.-287T>C upstream_gene_variant 0.39 ethambutol
embA 4243460 c.228C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4244051 c.819T>C synonymous_variant 0.2 ethambutol
embA 4244061 p.Leu277Asn missense_variant 0.24 ethambutol
embA 4244070 p.Val280Ile missense_variant 0.24 ethambutol
embA 4244075 c.843C>G synonymous_variant 0.22 ethambutol
embA 4244081 c.849C>A synonymous_variant 0.21 ethambutol
embA 4244099 c.867T>C synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embA 4244102 c.870A>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embA 4244132 c.900G>C synonymous_variant 0.21 ethambutol
embA 4244165 c.933T>G synonymous_variant 0.24 ethambutol
embA 4244170 p.Gln313Arg missense_variant 0.24 ethambutol
embA 4244178 p.Ala316Ser missense_variant 0.31 ethambutol
embA 4244198 c.966C>A synonymous_variant 0.33 ethambutol
embA 4244207 c.975C>G synonymous_variant 0.29 ethambutol
embA 4244213 c.981C>G synonymous_variant 0.27 ethambutol
embA 4244219 c.987C>G synonymous_variant 0.23 ethambutol
embA 4244823 p.Val531Met missense_variant 0.29 ethambutol
embA 4244856 p.Ala542Gln missense_variant 0.44 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.51 ethambutol
embA 4244886 c.1654C>T synonymous_variant 0.34 ethambutol
embA 4244897 c.1665T>C synonymous_variant 0.35 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 0.31 ethambutol
embA 4244904 p.Val558Leu missense_variant 0.33 ethambutol Uncertain significance
embA 4244909 c.1677C>G synonymous_variant 0.34 ethambutol
embA 4244916 c.1684C>T synonymous_variant 0.32 ethambutol
embA 4244921 c.1689C>G synonymous_variant 0.35 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.33 ethambutol
embA 4244936 c.1704C>G synonymous_variant 0.35 ethambutol
embA 4244939 c.1707G>A synonymous_variant 0.35 ethambutol
embA 4245059 c.1827G>C synonymous_variant 0.2 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.2 ethambutol
embA 4245077 c.1845G>A synonymous_variant 0.19 ethambutol
embA 4245079 p.Trp616Leu missense_variant 0.19 ethambutol
embA 4245083 c.1851A>C synonymous_variant 0.33 ethambutol
embA 4245086 c.1854C>G synonymous_variant 0.2 ethambutol
embA 4245093 p.Ile621Val missense_variant 0.24 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 0.38 ethambutol
embA 4245136 p.Tyr635Phe missense_variant 0.26 ethambutol
embA 4245149 c.1917C>A synonymous_variant 0.24 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.21 ethambutol
embA 4245174 p.Ser648Thr missense_variant 0.26 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.36 ethambutol
embA 4245186 p.Thr652Ala missense_variant 0.36 ethambutol
embA 4245198 p.Leu656Val missense_variant 0.19 ethambutol Uncertain significance
embA 4245207 c.1975T>C synonymous_variant 0.32 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.34 ethambutol
embA 4245222 p.Tyr664Leu missense_variant 0.22 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embA 4245693 p.Ile821Val missense_variant 0.37 ethambutol
embA 4245705 p.His825Asn missense_variant 0.26 ethambutol
embA 4245709 p.Ala826Val missense_variant 0.27 ethambutol
embB 4245713 c.-801G>C upstream_gene_variant 0.27 ethambutol
embB 4245725 c.-789A>C upstream_gene_variant 0.33 ethambutol
embB 4245726 c.-788_-786delTTGinsCTC upstream_gene_variant 0.41 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.43 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.33 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.48 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 0.2 ethambutol
embA 4246028 c.2796G>C synonymous_variant 0.26 ethambutol Not assoc w R - Interim
embB 4246070 c.-444G>C upstream_gene_variant 0.23 ethambutol
embB 4246082 c.-432T>C upstream_gene_variant 0.2 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 0.24 ethambutol
embB 4246115 c.-399T>C upstream_gene_variant 0.26 ethambutol
embA 4246254 p.Leu1008Met missense_variant 0.23 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 0.29 ethambutol
embA 4246265 c.3033C>T synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embB 4246268 c.-246G>A upstream_gene_variant 0.23 ethambutol
embA 4246279 p.Ala1016Val missense_variant 0.24 ethambutol
embB 4246346 c.-168C>G upstream_gene_variant 0.42 ethambutol
embA 4246359 p.Ala1043Ser missense_variant 0.37 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.35 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.36 ethambutol
embA 4246413 p.His1061Tyr missense_variant 0.18 ethambutol
embB 4247365 c.852A>C synonymous_variant 0.39 ethambutol
embB 4247371 c.858C>G synonymous_variant 0.43 ethambutol
embB 4247375 p.Leu288Val missense_variant 0.31 ethambutol
embB 4247380 c.867C>G synonymous_variant 0.33 ethambutol
embB 4247386 c.873T>C synonymous_variant 0.5 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.35 ethambutol
embB 4247395 c.882C>A synonymous_variant 0.35 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.49 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.41 ethambutol Not assoc w R - Interim
embB 4247446 c.933C>T synonymous_variant 0.36 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.51 ethambutol
embB 4247494 c.981G>A synonymous_variant 0.44 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.53 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.55 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.55 ethambutol
embB 4247519 c.1006C>T synonymous_variant 0.42 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.57 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.44 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.33 ethambutol
embB 4247576 c.1063C>T synonymous_variant 0.34 ethambutol
embB 4247579 p.Ala356Ile missense_variant 0.4 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embB 4247608 c.1095G>C synonymous_variant 0.43 ethambutol
embB 4247629 c.1116C>G synonymous_variant 0.24 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.34 ethambutol
embB 4247638 c.1125G>C synonymous_variant 0.22 ethambutol
embB 4247645 p.Glu378Thr missense_variant 0.23 ethambutol
embB 4247648 p.Ala379Ser missense_variant 0.23 ethambutol
embB 4247657 p.Pro382Ala missense_variant 0.22 ethambutol
embB 4247679 p.Met389Thr missense_variant 0.21 ethambutol
embB 4247684 c.1171T>C synonymous_variant 0.32 ethambutol
embB 4247722 c.1209G>C synonymous_variant 0.23 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.2 ethambutol
embB 4247728 c.1215G>A synonymous_variant 0.2 ethambutol
embB 4247743 c.1230C>G synonymous_variant 0.23 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.19 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.24 ethambutol
embB 4247915 p.Arg468Ser missense_variant 0.2 ethambutol
embB 4247920 c.1407T>C synonymous_variant 0.19 ethambutol
embB 4247932 c.1419C>G synonymous_variant 0.2 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.21 ethambutol
embB 4247948 p.Val479Leu missense_variant 0.28 ethambutol Uncertain significance
embB 4247951 p.Ser480Ala missense_variant 0.22 ethambutol
embB 4247972 p.Thr487Phe missense_variant 0.31 ethambutol
embB 4247975 p.Val488Met missense_variant 0.23 ethambutol
embB 4247983 c.1470G>C synonymous_variant 0.31 ethambutol
embB 4247992 c.1479G>A synonymous_variant 0.35 ethambutol Not assoc w R - Interim
embB 4248007 c.1494C>G synonymous_variant 0.55 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.37 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.38 ethambutol Uncertain significance
embB 4248044 p.Lys511Asp missense_variant 0.35 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.5 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.48 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.36 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.4 ethambutol
embB 4248115 c.1602C>T synonymous_variant 0.47 ethambutol Not assoc w R
embB 4248118 c.1605T>C synonymous_variant 0.39 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.45 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.35 ethambutol
embB 4248139 c.1626C>A synonymous_variant 0.37 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.44 ethambutol
embB 4248154 c.1641G>C synonymous_variant 0.34 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.34 ethambutol Not assoc w R - Interim
embB 4248160 c.1647C>T synonymous_variant 0.29 ethambutol Not assoc w R - Interim
embB 4248161 c.1648C>T synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embB 4248172 c.1659G>C synonymous_variant 0.33 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.33 ethambutol
embB 4248199 c.1686A>C synonymous_variant 0.25 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.24 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.31 ethambutol Uncertain significance
embB 4248217 c.1704C>G synonymous_variant 0.3 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embB 4248226 c.1713G>C synonymous_variant 0.21 ethambutol
embB 4248232 c.1719G>A synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embB 4248233 c.1720C>T synonymous_variant 0.38 ethambutol
embB 4248241 c.1728C>T synonymous_variant 0.3 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.46 ethambutol
embB 4248280 c.1767C>G synonymous_variant 0.47 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.53 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.52 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.36 ethambutol
embB 4248328 c.1815G>A synonymous_variant 0.35 ethambutol
embB 4248337 c.1824G>C synonymous_variant 0.31 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.26 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.24 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.4 ethambutol
embB 4248361 c.1848A>G synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embB 4248362 p.Ser617Lys missense_variant 0.25 ethambutol
embB 4248407 p.Leu632Val missense_variant 0.2 ethambutol
embB 4248412 p.Phe633Leu missense_variant 0.2 ethambutol
embB 4248416 p.Leu635Met missense_variant 0.22 ethambutol
embB 4248424 c.1911G>A synonymous_variant 0.25 ethambutol
embB 4248430 c.1917T>C synonymous_variant 0.24 ethambutol
embB 4248448 c.1935C>T synonymous_variant 0.24 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.22 ethambutol
embB 4249339 c.2826T>C synonymous_variant 0.26 ethambutol
embB 4249343 p.Val944Ile missense_variant 0.26 ethambutol
embB 4249351 c.2838C>G synonymous_variant 0.26 ethambutol
embB 4249354 c.2841G>A synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embB 4249369 c.2856T>C synonymous_variant 0.35 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.33 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.33 ethambutol
embB 4249382 p.Pro957Ala missense_variant 0.33 ethambutol
embB 4249387 p.Glu958Asp missense_variant 0.34 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.4 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.38 ethambutol Uncertain significance
embB 4249432 c.2919A>G synonymous_variant 0.32 ethambutol
embB 4249433 c.2920C>T synonymous_variant 0.3 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.24 ethambutol
embB 4249447 c.2934G>C synonymous_variant 0.25 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.26 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.36 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.36 ethambutol
embB 4249492 c.2979C>A synonymous_variant 0.33 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.4 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4249528 c.3015C>T synonymous_variant 0.27 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.41 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.42 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.27 ethambutol
embB 4249545 p.Lys1011Arg missense_variant 0.26 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.23 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.21 ethambutol
embB 4249693 c.3180T>C synonymous_variant 0.2 ethambutol
embB 4249711 c.3198G>A synonymous_variant 0.21 ethambutol
aftB 4267529 c.1308T>C synonymous_variant 0.19 ethambutol
aftB 4267535 c.1302A>G synonymous_variant 0.2 ethambutol
aftB 4267574 c.1263G>C synonymous_variant 0.2 ethambutol
aftB 4267592 c.1245C>G synonymous_variant 0.22 ethambutol Not assoc w R - Interim
aftB 4267595 c.1242C>T synonymous_variant 0.27 ethambutol
aftB 4267622 c.1213_1215delTCGinsAGC synonymous_variant 0.48 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.34 ethambutol
aftB 4267634 p.Arg401His missense_variant 0.49 ethambutol
aftB 4267647 p.Asp397Cys missense_variant 0.5 ethambutol
aftB 4267655 c.1182C>G synonymous_variant 0.37 ethambutol
aftB 4267670 c.1167G>A synonymous_variant 0.31 ethambutol
aftB 4267676 c.1161G>A synonymous_variant 0.23 ethambutol Not assoc w R - Interim
aftB 4267685 c.1152T>C synonymous_variant 0.21 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 0.24 ethambutol
ubiA 4269131 p.Leu235Met missense_variant 0.22 ethambutol Uncertain significance
aftB 4269138 c.-302C>T upstream_gene_variant 0.22 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.32 ethambutol Not assoc w R - Interim
ubiA 4269152 p.Ala228Ser missense_variant 0.23 ethambutol Uncertain significance
aftB 4269153 c.-317C>G upstream_gene_variant 0.23 ethambutol
aftB 4269156 c.-320C>G upstream_gene_variant 0.23 ethambutol
aftB 4269164 c.-328T>C upstream_gene_variant 0.39 ethambutol
ubiA 4269177 c.657G>A synonymous_variant 0.45 ethambutol Not assoc w R - Interim
aftB 4269183 c.-347T>C upstream_gene_variant 0.34 ethambutol
aftB 4269210 c.-374G>A upstream_gene_variant 0.35 ethambutol
ubiA 4269222 c.612T>G synonymous_variant 0.4 ethambutol Not assoc w R - Interim
aftB 4269225 c.-389C>A upstream_gene_variant 0.33 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 0.32 ethambutol
aftB 4269242 c.-406C>T upstream_gene_variant 0.24 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.32 ethambutol
aftB 4269248 c.-412C>T upstream_gene_variant 0.3 ethambutol
aftB 4269252 c.-416C>G upstream_gene_variant 0.23 ethambutol
ethR 4327423 c.-126G>C upstream_gene_variant 0.25 ethionamide
ethR 4327426 c.-123A>G upstream_gene_variant 0.26 ethionamide
ethR 4327435 c.-114T>G upstream_gene_variant 0.26 ethionamide
ethR 4327438 c.-111A>G upstream_gene_variant 0.26 ethionamide
ethR 4327447 c.-102G>T upstream_gene_variant 0.23 ethionamide
ethR 4327459 c.-90G>C upstream_gene_variant 0.24 ethionamide
whiB6 4338288 c.234G>T synonymous_variant 0.19 kanamycin
capreomycin
amikacin
whiB6 4338291 c.231A>C synonymous_variant 0.21 kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
whiB6 4338300 c.222G>C synonymous_variant 0.2 kanamycin
capreomycin
amikacin
whiB6 4338315 c.207C>A synonymous_variant 0.24 kanamycin
capreomycin
amikacin
whiB6 4338324 c.198C>T synonymous_variant 0.26 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
whiB6 4338327 c.195C>T synonymous_variant 0.27 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
whiB6 4338333 c.189A>C synonymous_variant 0.26 kanamycin
capreomycin
amikacin
whiB6 4338351 c.171G>C synonymous_variant 0.28 kanamycin
capreomycin
amikacin
whiB6 4338371 p.Thr51Ala missense_variant 0.26 kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
gid 4407588 c.615A>G synonymous_variant 1.0 streptomycin Not assoc w R
gid 4407927 p.Glu92Asp missense_variant 1.0 streptomycin Not assoc w R