TB-Profiler result

Run: SRR6046577
Summary

Run ID: SRR6046577

Sample name:

Date: 2024-04-14T03:46:32.648658

Number of reads: 685679

Percentage reads mapped: 22.42

Median coverage: 0.0

Strain: lineage4.6.3;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.6.3 Euro-American None 0.11
lineage4 Euro-American None 0.85
lineage4.9 Euro-American (H37Rv-like) None 0.86
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Asp311Gly Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide ethA c.1150_1152delGTTinsAC Assoc w R
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.649_651delACGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.751_753delTTGinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1777_1779delGTCinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2344_2346delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303579 c.649_651delACGinsTC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303681 c.751_753delTTGinsCC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304707 c.1777_1779delGTCinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305274 c.2344_2346delTCGinsGC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247445 p.Asp311Gly missense_variant 1.0 ethambutol Mutation from literature
ethA 4326322 c.1150_1152delGTTinsAC frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 609 c.609C>G synonymous_variant 1.0 isoniazid
dnaA 624 c.624C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 627 c.627G>A synonymous_variant 1.0 isoniazid
dnaA 633 c.633T>C synonymous_variant 1.0 isoniazid
dnaA 634 c.634_636delCTCinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 645 c.645A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 648 c.648C>T synonymous_variant 1.0 isoniazid
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 663 c.663A>C synonymous_variant 1.0 isoniazid
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 673 p.Ala225Thr missense_variant 1.0 isoniazid Uncertain significance
dnaA 678 c.678A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 687 c.687C>T synonymous_variant 0.67 isoniazid
dnaA 699 c.699G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 714 c.714C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 765 c.765G>A synonymous_variant 1.0 isoniazid
dnaA 768 c.768C>T synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>C synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 819 c.819C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 873 c.873C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 894 c.894G>A synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 1.0 isoniazid
dnaA 915 c.915C>T synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 930 c.930G>A synonymous_variant 1.0 isoniazid
gyrB 6193 c.954G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6196 c.957C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6199 c.960C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6203 c.964_965delAGinsTC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6715 c.1476C>T synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6748 c.-554G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6763 c.-539G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6798 p.Gly520Ala missense_variant 0.98 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrB 6824 c.1585C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6860 p.Ser541Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 6865 c.-437G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6866 c.-436C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6872 c.1633_1635delTTGinsCC frameshift_variant&missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7143 p.Gln635Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7343 c.42G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7352 c.51G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7403 c.102C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7415 c.114C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7418 c.117C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7460 c.159C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7496 c.195C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7506 p.Ser69Gly missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7520 c.219G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7538 c.237G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7571 c.270G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7758 c.457_459delATCinsGT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7853 c.552C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7906 p.Phe202Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7923 p.His208Phe missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7941 p.Glu214Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7958 c.657C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8270 c.969G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8400 p.Asp367Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8570 p.Glu423Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8576 c.1275C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8580 p.Ile427Val missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8591 c.1290C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8684 c.1383G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8690 c.1389C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9070 p.Thr590Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9116 c.1815G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9125 c.1824C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9174 c.1873_1875delCTGinsTA frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9212 c.1911G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9362 c.2061C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9425 c.2124C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9432 c.2131C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9455 c.2154T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9468 c.2167C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491154 p.Glu124Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491160 c.378G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491172 c.390C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491208 c.426G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491223 c.441C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491319 c.537G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491321 p.Ala180Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491334 c.552C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491344 p.Ala188Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491355 c.573C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491370 c.588C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491376 c.594G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491385 c.603G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491392 p.Thr204Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491453 p.Gly224Asp missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491461 p.Lys227Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491562 c.780C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491685 c.903G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491694 c.912C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575527 c.180G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575545 c.198C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575548 c.201C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575581 c.234C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575596 c.249C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575597 p.Ile84Val missense_variant 1.0 ethionamide
isoniazid
mshA 575620 c.273G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575627 c.280_282delGCAinsTG frameshift_variant&stop_gained 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575634 p.Ala96Val missense_variant 1.0 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575644 c.297G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575646 p.Val100Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575678 p.Asn111His missense_variant 1.0 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575692 c.345G>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575714 p.Tyr123His missense_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575779 p.Glu144Asp missense_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575837 c.490C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575843 p.Arg166Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575923 c.577_578delGG frameshift_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575929 c.582_583insCG frameshift_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575939 c.592C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575984 c.637_639delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657601 c.-131A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657608 c.-138C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657611 c.-141C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657636 c.-167_-166delAGinsTC upstream_gene_variant 1.0 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657647 c.-177C>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657662 c.-192C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657677 c.-209_-207delAACinsGGT upstream_gene_variant 1.0 ethionamide
Rv0565c 657701 c.-233_-231delCTCinsTG upstream_gene_variant 1.0 ethionamide
Rv0565c 657724 c.-254A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
hadA 731823 c.-107C>T upstream_gene_variant 1.0 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 1.0 isoniazid
nusG 734367 c.114C>G synonymous_variant 1.0 rifampicin
nusG 734384 p.Ser44Thr missense_variant 1.0 rifampicin
nusG 734391 c.138C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734403 c.150C>T synonymous_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734508 c.255C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734538 c.285C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734562 c.309G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>C synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734859 c.606G>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>A synonymous_variant 1.0 rifampicin
nusG 734863 c.610_612delACGinsTC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734886 c.633A>G synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734922 c.669C>T synonymous_variant 1.0 rifampicin
nusG 734925 c.672C>T synonymous_variant 1.0 rifampicin
nusG 734928 c.675A>G synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
rpoB 760059 p.Tyr85Thr missense_variant 1.0 rifampicin
rpoB 760064 c.258G>A synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760090 p.Gly95Glu missense_variant 1.0 rifampicin
rpoB 760094 c.288G>C synonymous_variant 1.0 rifampicin
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>G synonymous_variant 1.0 rifampicin
rpoB 760113 p.Asp103Asn missense_variant 1.0 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>G synonymous_variant 1.0 rifampicin
rpoB 760127 p.Asp107Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760155 p.Lys117Arg missense_variant 1.0 rifampicin
rpoB 760160 p.Asp118Glu missense_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760178 c.372G>T synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>G synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760193 c.387C>G synonymous_variant 1.0 rifampicin
rpoB 760199 c.393C>G synonymous_variant 1.0 rifampicin
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>G synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760317 c.511_513delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 1.0 rifampicin
rpoB 760354 p.Glu183Ala missense_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760388 c.582C>T synonymous_variant 1.0 rifampicin
rpoB 760389 c.583_585delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 760407 c.601_603delAGCinsGT frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760449 p.Thr215Leu missense_variant 1.0 rifampicin
rpoB 760457 c.651C>G synonymous_variant 1.0 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760490 c.684C>G synonymous_variant 1.0 rifampicin
rpoB 760523 c.717C>T synonymous_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Arg missense_variant 1.0 rifampicin
rpoB 760547 c.741G>T synonymous_variant 1.0 rifampicin
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760585 p.Asn260Ser missense_variant 1.0 rifampicin
rpoB 760587 p.Thr261Ala missense_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760593 p.Gly263Asn missense_variant 1.0 rifampicin
rpoB 760608 c.802C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760643 c.837G>A synonymous_variant 1.0 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760668 c.862_864delACGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>G synonymous_variant 1.0 rifampicin
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760734 p.Val310Leu missense_variant 1.0 rifampicin
rpoB 760796 c.990A>G synonymous_variant 1.0 rifampicin
rpoB 760800 p.Val332Ile missense_variant 1.0 rifampicin Uncertain significance
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760829 c.1023C>G synonymous_variant 1.0 rifampicin
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>G synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760868 c.1062C>G synonymous_variant 1.0 rifampicin
rpoB 760880 c.1074G>C synonymous_variant 1.0 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760887 p.Thr361Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 760916 c.1110C>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760938 c.1132C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760964 c.1158C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761138 c.1332C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 1.0 rifampicin
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761360 c.1554T>G synonymous_variant 1.0 rifampicin
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761369 p.Glu521Asp missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761411 c.1605G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761437 p.Ala544Asp missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761452 p.Val549Ala missense_variant 1.0 rifampicin
rpoB 761462 c.1656C>G synonymous_variant 1.0 rifampicin
rpoB 761471 c.1665C>G synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761495 c.1689G>A synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761508 c.1702_1704delTCTinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>G synonymous_variant 1.0 rifampicin
rpoB 761603 c.1797C>G synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761627 c.1821C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761651 c.1845C>T synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761714 c.1908C>G synonymous_variant 1.0 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 1.0 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>G synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662Gln missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761814 p.Ala670Asn missense_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761870 p.Asp688Glu missense_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.99 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762050 c.2244G>A synonymous_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>G synonymous_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>G synonymous_variant 1.0 rifampicin
rpoB 762212 c.2406G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.99 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>G upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.98 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.98 rifampicin Uncertain significance
rpoC 762527 c.-843G>C upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoB 762537 c.2731_2733delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762560 c.-810A>C upstream_gene_variant 1.0 rifampicin
rpoC 762575 c.-795C>T upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoB 762768 p.Pro988Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 762779 c.-591C>T upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762795 p.Asp997Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 762798 p.Ala998Ser missense_variant 1.0 rifampicin
rpoC 762803 c.-567C>T upstream_gene_variant 1.0 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762820 p.Phe1005Tyr missense_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 1.0 rifampicin
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 1.0 rifampicin
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763058 c.-312C>G upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoB 763203 c.3397_3399delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 763207 p.Ser1134Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763241 c.-129G>A upstream_gene_variant 0.98 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 1.0 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 1.0 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763426 c.57C>T synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763447 c.78C>T synonymous_variant 1.0 rifampicin
rpoC 763465 c.96G>A synonymous_variant 1.0 rifampicin
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763483 c.114G>C synonymous_variant 1.0 rifampicin
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 1.0 rifampicin
rpoC 763636 c.267T>G synonymous_variant 1.0 rifampicin
rpoC 763654 c.285C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>G synonymous_variant 1.0 rifampicin
rpoC 763699 c.330G>T synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763781 c.412_414delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 763790 p.Glu141Thr missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763844 p.Arg159Lys missense_variant 1.0 rifampicin
rpoC 763852 c.483C>G synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763867 c.498C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763903 c.534G>A synonymous_variant 1.0 rifampicin
rpoC 763910 c.541_543delCTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763930 c.561G>A synonymous_variant 1.0 rifampicin
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763947 p.Ala193Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763996 c.627T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763999 c.630C>T synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>T synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 1.0 rifampicin
rpoC 764030 p.Asp221Thr missense_variant 1.0 rifampicin
rpoC 764039 p.Ser224Asp missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764048 p.Thr227Val missense_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764087 p.Leu240Ile missense_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764104 c.735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764134 c.765C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764149 c.780G>C synonymous_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764167 c.798G>A synonymous_variant 1.0 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 0.98 rifampicin
rpoC 764195 p.Ser276Ala missense_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764213 p.Arg282Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 764236 c.867G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>G synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 1.0 rifampicin
rpoC 764554 c.1185C>G synonymous_variant 1.0 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764632 c.1263T>G synonymous_variant 1.0 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 764656 c.1287C>G synonymous_variant 1.0 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 1.0 rifampicin
rpoC 764812 c.1443C>G synonymous_variant 1.0 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>C synonymous_variant 1.0 rifampicin
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764902 c.1533C>G synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764944 c.1575C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764947 c.1578G>A synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765007 c.1638T>C synonymous_variant 1.0 rifampicin
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765065 c.1696C>T synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765079 c.1710T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765143 p.Val592Ile missense_variant 1.0 rifampicin
rpoC 765151 c.1782G>T synonymous_variant 1.0 rifampicin
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765339 p.Gln657Arg missense_variant 1.0 rifampicin Uncertain significance
rpoC 765343 c.1974G>C synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765358 p.Met663Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765359 p.Ala664Thr missense_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765404 p.Leu679Met missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765452 p.Ala695Ile missense_variant 0.97 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765505 c.2136C>G synonymous_variant 1.0 rifampicin
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765535 c.2166C>T synonymous_variant 1.0 rifampicin
rpoC 765548 c.2179_2180delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>G synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765611 p.His748Ala missense_variant 1.0 rifampicin
rpoC 765621 p.Glu751Ala missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765637 c.2268C>G synonymous_variant 1.0 rifampicin
rpoC 765661 c.2292T>G synonymous_variant 1.0 rifampicin
rpoC 765676 c.2307G>A synonymous_variant 1.0 rifampicin
rpoC 765685 c.2316G>A synonymous_variant 1.0 rifampicin
rpoC 765688 c.2319G>C synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765718 p.Asp783Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765727 c.2358T>G synonymous_variant 1.0 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765742 p.Glu791Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 1.0 rifampicin
rpoC 765781 p.Asp804Glu missense_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>G synonymous_variant 1.0 rifampicin
rpoC 765871 c.2502T>C synonymous_variant 1.0 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765910 c.2541G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>G synonymous_variant 1.0 rifampicin
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 1.0 rifampicin
rpoC 766299 p.Thr977Met missense_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766429 c.3060C>G synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766468 c.3099G>A synonymous_variant 1.0 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766517 p.Thr1050Ala missense_variant 1.0 rifampicin
rpoC 766526 c.3157_3159delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766546 p.Glu1059Asp missense_variant 1.0 rifampicin
rpoC 766547 p.Arg1060Lys missense_variant 1.0 rifampicin
rpoC 766568 c.3199_3201delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Phe missense_variant 1.0 rifampicin
rpoC 766609 c.3240_3241delCTinsGCCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766612 c.3243C>G synonymous_variant 1.0 rifampicin
rpoC 766613 c.3245_3246delAG frameshift_variant 1.0 rifampicin
rpoC 766618 c.3249G>C synonymous_variant 1.0 rifampicin
rpoC 766625 c.3256C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766652 p.Ser1095Thr missense_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 1.0 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>G synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766753 c.3384C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766787 p.Glu1140Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766849 c.3480G>A synonymous_variant 1.0 rifampicin
rpoC 766882 c.3513C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766888 c.3519G>C synonymous_variant 1.0 rifampicin
rpoC 766891 c.3522G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 1.0 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766957 c.3588G>A synonymous_variant 1.0 rifampicin
rpoC 766960 c.3591C>T synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766975 c.3606C>G synonymous_variant 1.0 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 0.98 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767030 c.3661C>T synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>G synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>G synonymous_variant 1.0 rifampicin
rpoC 767155 c.3786C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767163 p.Asn1265Ser missense_variant 1.0 rifampicin
rpoC 767180 c.3811_3813delGCGinsAC frameshift_variant&missense_variant 0.99 rifampicin
rpoC 767186 p.Gln1273Glu missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>T synonymous_variant 0.98 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767254 c.3885G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767265 p.Ala1299Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 767267 p.Ala1300Pro missense_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767306 c.3937_3938delAGinsTC synonymous_variant 1.0 rifampicin
mmpL5 775826 c.2655G>T synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775832 c.2647_2649delGCCinsTG frameshift_variant&missense_variant 0.87 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775841 c.2640G>C synonymous_variant 0.52 clofazimine
bedaquiline
mmpL5 775847 c.2634G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 775862 c.2619G>C synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775882 p.Asn867His missense_variant 0.44 clofazimine
bedaquiline
mmpL5 775885 p.Ile866Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775886 c.2595A>G synonymous_variant 0.47 clofazimine
bedaquiline
mmpL5 775892 c.2589C>T synonymous_variant 0.47 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.41 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775910 c.2571G>C synonymous_variant 0.52 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTA frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775939 p.Ala848Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775940 c.2541C>G synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.58 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.39 clofazimine
bedaquiline
mmpL5 775954 c.2527C>T synonymous_variant 0.94 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775957 p.Ile842Val missense_variant 0.63 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775971 p.Ala837Val missense_variant 0.71 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777094 c.1387T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777095 c.1386T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777106 p.Ser459Pro missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777110 c.1371T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777115 p.Met456Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777122 c.1359C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777126 p.Ser452Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777133 p.Val450Ile missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777142 p.Val447Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777143 c.1338G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777146 c.1335C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777194 p.Glu429Val missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777206 c.1273_1275delCTAinsAT frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781592 c.33T>G synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781625 c.66G>C synonymous_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781634 c.75G>A synonymous_variant 1.0 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781679 c.120C>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781694 c.135G>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781721 c.162C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>G synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781763 c.204C>G synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 1.0 streptomycin
rpsL 781841 c.282C>A synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>A synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 1.0 streptomycin
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800573 c.-236C>T upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 1.0 linezolid
rplC 800588 c.-221C>G upstream_gene_variant 1.0 linezolid
rplC 800589 c.-220_-219delAGinsTC upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800624 c.-185G>A upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800663 c.-146G>A upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800700 c.-109C>A upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 1.0 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801176 p.Phe123Tyr missense_variant 1.0 linezolid
rplC 801210 c.402T>C synonymous_variant 1.0 linezolid
rplC 801220 c.412_414delAGTinsGG frameshift_variant&missense_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801229 p.Ala141Thr missense_variant 0.98 linezolid
rplC 801247 c.439_441delCGTinsAG frameshift_variant&missense_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 0.99 linezolid
rplC 801258 c.450C>G synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801271 p.Ala155Ser missense_variant 1.0 linezolid
rplC 801281 p.Ala158Gly missense_variant 1.0 linezolid
rplC 801307 c.499_501delGCCinsTG frameshift_variant&missense_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801337 p.Val177Thr missense_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801366 c.558T>C synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303489 c.559C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303557 c.627G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303722 c.792C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303768 p.Ser280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303824 c.894G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304016 c.1086C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304019 c.1089C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304028 c.1098C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304517 c.1587C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304550 c.1620C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304608 p.Thr560Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304688 p.Asp586Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304754 p.Glu608Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304784 c.1854T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304800 c.1870C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304845 p.Ala639Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304877 c.1947T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304880 c.1950C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304890 p.Ile654Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304904 c.1974G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304919 c.1989C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305173 p.Asn748Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305189 c.2259G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305190 p.Ala754Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305197 p.Ala756Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305219 c.2289T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305234 c.2304G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305259 c.2329T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305277 p.His783Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305306 c.2376A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305310 p.Arg794Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305320 p.Gln797Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305330 c.2400C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305331 p.Glu801Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305360 c.2430G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364787 p.Gln125His missense_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364796 p.Gln128His missense_variant 1.0 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 1.0 pyrazinamide
sigE 1364845 c.433C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364856 c.444C>T synonymous_variant 1.0 pyrazinamide
sigE 1364859 c.447C>G synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 1.0 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 1.0 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364926 c.514_516delAACinsGT frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
atpE 1461089 c.45G>C synonymous_variant 1.0 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 1.0 bedaquiline
atpE 1461125 c.81T>C synonymous_variant 1.0 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461153 p.Ser37Ala missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461164 c.120C>T synonymous_variant 1.0 bedaquiline
atpE 1461167 c.123G>C synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461176 c.132G>A synonymous_variant 1.0 bedaquiline
atpE 1461179 c.135G>T synonymous_variant 1.0 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461188 c.144G>A synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 1.0 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.82 bedaquiline
rrs 1471514 n.-332A>C upstream_gene_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471517 n.-329T>C upstream_gene_variant 0.89 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471521 n.-325T>C upstream_gene_variant 0.88 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471540 n.-306_-305delTGinsCC upstream_gene_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471550 n.-296T>C upstream_gene_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472292 n.447A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472298 n.453G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472305 n.460_466delTTCTCTCinsCTTTTGTTG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472683 n.838_839insTA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473111 n.1266A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473120 n.1275C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1474708 n.1052dupG non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474711 n.1054_1055insA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474715 n.1061delA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475604 n.1947A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475607 n.1950_1951delATinsC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475620 n.1963T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475635 n.1978G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476262 n.2605G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476691 n.3034T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673778 c.-424C>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673796 c.-406G>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673799 c.-403T>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673805 c.-397G>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673808 c.-394A>C upstream_gene_variant 0.95 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 0.93 ethionamide
isoniazid
fabG1 1673830 p.Lys131Arg missense_variant 0.93 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 0.93 ethionamide
isoniazid
fabG1 1673844 p.Met135Ile missense_variant 0.93 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673856 c.-346T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673865 c.-337C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 1.0 ethionamide
isoniazid
inhA 1673877 c.-325C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673937 c.-265G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1673949 c.-253G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673960 p.Ala174Val missense_variant 0.92 ethionamide
isoniazid
inhA 1674452 p.Ala84Asp missense_variant 0.9 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 0.96 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674542 p.Ala114Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674636 c.435C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674651 c.450C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674702 c.501G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674737 p.Ala179Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674804 c.603G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid
inhA 1674816 c.615T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674819 c.618G>A synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674825 c.624C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674830 p.Glu210Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674835 p.Gly212Ser missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674839 p.Ala213Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1674848 p.Gln216Arg missense_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1674855 c.654C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674892 p.Asn231Asp missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674900 c.699G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674954 c.753G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674963 c.762G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674965 c.765_767delTGA disruptive_inframe_deletion 1.0 ethionamide
isoniazid
inhA 1674970 c.769_770insCGG disruptive_inframe_insertion 1.0 ethionamide
isoniazid
inhA 1674973 p.Ile258Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>A synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833517 c.-24delC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833540 c.-2_-1delATinsC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833547 c.6G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833622 c.81C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833658 c.117C>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833770 p.Asn77His missense_variant 1.0 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833814 c.273C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833820 c.279G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833835 c.294C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833988 c.447C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833995 c.454C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834018 c.477C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834042 c.501G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834054 c.513C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834285 c.744G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834288 c.747C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834333 c.792C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834408 c.867C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834477 c.936C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834482 p.Glu314Gly missense_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834522 c.981C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834527 p.Arg329Gln missense_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834667 c.1126_1128delGCGinsTC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834751 c.1210_1212delCTTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834761 p.Phe407Tyr missense_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834777 c.1236C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 1.0 linezolid
tsnR 1853361 c.-245_-243delTTGinsCC upstream_gene_variant 1.0 linezolid
tsnR 1853372 c.-234A>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853411 c.-195C>T upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853438 c.-168C>G upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 1.0 linezolid
tsnR 1853474 c.-132C>G upstream_gene_variant 1.0 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 1.0 linezolid
tsnR 1853493 c.-113_-112delGCinsCA upstream_gene_variant 1.0 linezolid
tsnR 1853502 c.-104A>G upstream_gene_variant 1.0 linezolid
tsnR 1853516 c.-90C>G upstream_gene_variant 1.0 linezolid
tsnR 1853525 c.-81G>T upstream_gene_variant 1.0 linezolid
tsnR 1853528 c.-78G>C upstream_gene_variant 1.0 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 1.0 linezolid
tsnR 1853546 c.-60C>G upstream_gene_variant 1.0 linezolid
tsnR 1853552 c.-54C>A upstream_gene_variant 1.0 linezolid
tsnR 1853561 c.-45G>C upstream_gene_variant 1.0 linezolid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517956 c.-159G>A upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2518004 c.-111G>A upstream_gene_variant 1.0 isoniazid
kasA 2518193 p.Pro27Ala missense_variant 1.0 isoniazid
kasA 2518199 p.Ile29Val missense_variant 1.0 isoniazid
kasA 2518219 c.105T>C synonymous_variant 1.0 isoniazid
kasA 2518220 c.106_108delCTGinsTA frameshift_variant&stop_gained 1.0 isoniazid
kasA 2518240 c.126C>T synonymous_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518269 p.Thr52Ser missense_variant 1.0 isoniazid
kasA 2518273 c.159G>A synonymous_variant 1.0 isoniazid
kasA 2518282 c.168A>C synonymous_variant 1.0 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 1.0 isoniazid
kasA 2518288 c.174C>G synonymous_variant 1.0 isoniazid
kasA 2518300 c.186T>A synonymous_variant 1.0 isoniazid
kasA 2518303 c.189C>T synonymous_variant 1.0 isoniazid
kasA 2518315 c.201G>C synonymous_variant 1.0 isoniazid
kasA 2518333 c.219C>A synonymous_variant 1.0 isoniazid
kasA 2518336 c.222A>G synonymous_variant 1.0 isoniazid
kasA 2518348 c.234A>G synonymous_variant 1.0 isoniazid
kasA 2518360 c.246C>T synonymous_variant 1.0 isoniazid
kasA 2518374 p.Gly87Ala missense_variant 1.0 isoniazid
kasA 2518488 p.Ser125Thr missense_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518540 c.426T>G synonymous_variant 1.0 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>T synonymous_variant 1.0 isoniazid
kasA 2518597 c.483C>T synonymous_variant 1.0 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.96 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518648 c.534C>T synonymous_variant 1.0 isoniazid
kasA 2518651 c.537C>G synonymous_variant 1.0 isoniazid
kasA 2518657 c.543G>C synonymous_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2519140 c.1026G>A synonymous_variant 1.0 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 1.0 isoniazid
kasA 2519158 c.1044C>G synonymous_variant 1.0 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 1.0 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 1.0 isoniazid
kasA 2519194 c.1080G>C synonymous_variant 1.0 isoniazid
kasA 2519195 p.Thr361Ser missense_variant 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519209 c.1095C>G synonymous_variant 1.0 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 1.0 isoniazid
kasA 2519224 c.1110C>G synonymous_variant 1.0 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 1.0 isoniazid
kasA 2519248 c.1134C>G synonymous_variant 1.0 isoniazid
kasA 2519260 c.1146T>G synonymous_variant 1.0 isoniazid
kasA 2519275 c.1161C>G synonymous_variant 1.0 isoniazid
kasA 2519278 c.1164A>G synonymous_variant 1.0 isoniazid
kasA 2519287 c.1173T>C synonymous_variant 1.0 isoniazid
kasA 2519293 c.1179T>C synonymous_variant 1.0 isoniazid
kasA 2519298 p.Arg395Gln missense_variant 1.0 isoniazid
kasA 2519305 c.1191A>C synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
kasA 2519323 c.1209G>A synonymous_variant 1.0 isoniazid
kasA 2519329 c.1215C>T synonymous_variant 1.0 isoniazid
kasA 2519332 c.1218C>G synonymous_variant 1.0 isoniazid
kasA 2519338 c.1224T>C synonymous_variant 1.0 isoniazid
kasA 2519341 c.1227G>C synonymous_variant 1.0 isoniazid
ahpC 2726303 c.111T>G synonymous_variant 1.0 isoniazid
ahpC 2726308 p.Thr39Ser missense_variant 1.0 isoniazid
ahpC 2726312 c.120T>C synonymous_variant 1.0 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 1.0 isoniazid
ahpC 2726324 c.132A>C synonymous_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726612 c.420C>G synonymous_variant 1.0 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 1.0 isoniazid
ahpC 2726657 c.465A>T synonymous_variant 1.0 isoniazid
ahpC 2726669 p.Asp159Glu missense_variant 1.0 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 1.0 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 1.0 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
folC 2747020 c.579C>G synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747026 c.573C>G synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747035 c.564C>T synonymous_variant 0.91 para-aminosalicylic_acid
folC 2747040 p.Ile187Val missense_variant 0.92 para-aminosalicylic_acid
folC 2747044 c.555C>T synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747059 c.540T>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747083 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747347 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747398 c.201C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747416 c.183A>G synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782441 p.Glu534Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782454 p.Gly530Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782496 p.Asp516Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782504 c.1539G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782510 c.1533G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782531 c.1512C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1504_1506delCTTinsTG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782576 c.1467C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782828 c.1215T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782846 p.Arg399Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782852 c.1191T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782864 c.1179T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782885 c.1156_1158delCTGinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782907 p.Lys379Arg missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782913 p.Ser377Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782924 c.1119G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 c.1114_1116delACAinsCG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782933 c.1110C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782945 c.1098C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782987 c.1056C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.670_672delGAAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783386 c.657G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783392 c.651C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783413 c.630G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783444 p.Gln200Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783449 c.594C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783516 c.526_527delTCinsAG synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.91 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783523 c.520C>T synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783601 c.442C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783646 p.Asp133Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783710 c.333C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783737 c.306C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783746 c.297G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783764 c.277_279delATGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783767 c.276C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783770 c.273G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783788 c.255T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783794 c.249G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783800 c.243G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783842 c.201C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783854 c.189C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783857 c.186C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783902 c.141C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783935 c.108C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783947 c.96C>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783950 c.93C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783986 c.57G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783989 c.54G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784013 c.30G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784017 p.Lys9Arg missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859708 c.711C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859735 c.684G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859747 c.672C>A synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859750 c.669C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859759 c.660C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859765 c.654G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859771 c.648T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859778 p.Val214Asp missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859780 p.Gln213Ala missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859801 c.618G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859909 c.510G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859918 c.501A>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859921 c.498C>G synonymous_variant 1.0 clofazimine
bedaquiline
Rv2752c 3064911 c.1281C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064931 p.Leu421Val missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064932 c.1260T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064935 c.1257A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064944 c.1248G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064947 c.1245A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064950 c.1242C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064956 p.Ser412Arg missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064969 p.Lys408Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065070 c.1122C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065076 c.1116T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065079 c.1113T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065087 c.1105A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid Not assoc w R - Interim
Rv2752c 3065088 c.1104A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065091 c.1101A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065106 c.1086C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065109 c.1081_1083delAGAinsTG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065126 p.Ser356Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1062A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065136 p.Ile352Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065150 p.Val348Ile missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065151 c.1041G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065160 c.1032C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065166 c.1026C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065562 c.630T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065568 c.624C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065576 p.Ala206Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065594 c.598C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065604 c.588G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065607 c.585C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065611 p.Thr194Arg missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065624 c.568C>A synonymous_variant 0.97 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.543T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065658 c.534G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065661 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065666 c.526T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065667 c.525A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065670 c.522C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065699 p.Ile165Val missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065703 c.489A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065706 c.486G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065715 c.475_477delTATinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065721 c.471G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065739 c.453G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065742 p.Thr150Ile missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065748 c.444T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065757 c.435C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065922 c.270T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065946 p.Gly82Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065972 p.Ile74Val missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065982 c.210G>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065987 p.Asp69Asn missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065997 c.195C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066003 c.189C>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066039 c.153C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 c.142T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066071 c.121T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066078 c.114C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066084 c.108C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066096 c.96G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Gly missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066129 c.63G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066132 c.60G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066146 c.46T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066153 c.37_39delTCCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066162 c.30C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066165 c.27T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066537 c.-346C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066601 c.-410C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066617 c.-426G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyA 3073914 c.558C>T synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073965 c.507C>T synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.98 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.98 para-aminosalicylic_acid
thyA 3073992 c.480C>T synonymous_variant 0.98 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 0.98 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.98 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074045 c.427C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074064 c.408C>T synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074100 c.372T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074103 c.369C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074121 p.Asp117Glu missense_variant 1.0 para-aminosalicylic_acid
lpqB 3623699 c.1212C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623711 c.1200G>C synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3623715 p.Ser399Gly missense_variant 0.91 bedaquiline
rifampicin
lpqB 3623729 c.1182G>C synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3623752 p.Ser387Ala missense_variant 0.92 bedaquiline
rifampicin
lpqB 3623757 p.Val385Ala missense_variant 0.92 bedaquiline
rifampicin
lpqB 3623762 p.Glu383Asp missense_variant 0.9 bedaquiline
rifampicin
lpqB 3624392 c.519C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624396 p.Ala172Val missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624412 p.Asn167His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624416 c.495G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624637 p.His92Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624649 p.Leu88Met missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624676 p.Asn79Asp missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624685 p.Ser76Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624687 p.Glu75Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624704 c.207G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624734 c.177A>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625077 c.-167C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625084 c.-174C>T upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625093 c.1519_1521delGAGinsAC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625102 c.1510_1512delGAAinsAG frameshift_variant&synonymous_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625117 c.-207T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625162 c.-252T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625204 c.1408_1410delTCGinsGC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625251 c.-341C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625336 c.-426C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625349 p.Ala422Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625357 c.-447T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625369 c.-459G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625599 p.Met339Leu missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625623 p.Thr331Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625627 p.Asp329Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625633 c.981C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625636 p.Ala326Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625708 c.906C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625803 c.-893C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626684 c.-71G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626735 c.-122C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626750 c.-137T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626756 c.594C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626759 c.591T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626776 c.-163A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626792 c.-179G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626795 c.-182C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626798 c.-185T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626822 c.-209T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626840 c.-227C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626843 c.-230G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626891 p.Ser153Phe missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626907 p.Asn148Ala missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626909 c.441C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626912 p.Thr146Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626924 c.-311G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 1.0 bedaquiline
rifampicin
mtrA 3626942 c.406_408delGTAinsAC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626962 p.Met130Leu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627116 c.-503G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627131 p.Ala73Lys missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627149 c.-536G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627197 c.-584T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627213 p.Arg46His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627224 c.-611G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627247 p.Ile35Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627248 c.-635C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627305 c.-692T>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3627323 c.25_27delTTGinsCT frameshift_variant&missense_variant 0.94 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ala missense_variant 0.91 bedaquiline
rifampicin
fbiB 3642581 c.1047A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642588 p.Leu352Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642609 p.Ser359His missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642634 p.Asp367Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642664 p.Val377Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642671 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642674 c.1140C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642683 c.1149C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642692 c.1158C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
rpoA 3877492 p.Gln339Pro missense_variant 1.0 rifampicin
rpoA 3877503 p.Ala335Gly missense_variant 0.92 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 1.0 rifampicin
rpoA 3877509 p.Glu333Asp missense_variant 1.0 rifampicin
rpoA 3877514 p.Thr332Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877532 p.Ala326Thr missense_variant 1.0 rifampicin
rpoA 3877535 p.Val325Ile missense_variant 1.0 rifampicin
rpoA 3877548 c.960C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877553 p.Glu319Gln missense_variant 1.0 rifampicin
rpoA 3877560 c.948C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3877575 c.933C>T synonymous_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877617 c.891G>C synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877689 c.819C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 1.0 rifampicin
rpoA 3877710 c.798C>G synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877797 c.711G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877824 p.Glu228Asp missense_variant 1.0 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877842 c.666A>C synonymous_variant 1.0 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.98 rifampicin
rpoA 3877875 c.633T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 0.98 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 0.98 rifampicin
rpoA 3877905 c.603A>C synonymous_variant 0.98 rifampicin
rpoA 3877908 c.600T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877959 c.549C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877968 c.540C>G synonymous_variant 0.96 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878013 c.495T>C synonymous_variant 1.0 rifampicin
rpoA 3878019 c.489A>G synonymous_variant 1.0 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>T synonymous_variant 1.0 rifampicin
rpoA 3878073 c.435C>G synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 1.0 rifampicin
rpoA 3878093 p.Val139Ile missense_variant 1.0 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>T synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878133 c.375C>T synonymous_variant 1.0 rifampicin
rpoA 3878142 p.Gly122Glu missense_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>G synonymous_variant 1.0 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878199 c.309T>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878220 c.288C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 1.0 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878262 c.244_246delAGCinsGA frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>G synonymous_variant 1.0 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 1.0 rifampicin
rpoA 3878379 c.129G>C synonymous_variant 1.0 rifampicin
rpoA 3878382 c.126G>A synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 1.0 rifampicin
rpoA 3878421 c.87A>T synonymous_variant 1.0 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 1.0 rifampicin
rpoA 3878427 c.81G>A synonymous_variant 1.0 rifampicin
rpoA 3878430 c.78G>C synonymous_variant 1.0 rifampicin
rpoA 3878442 c.64_66delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3878451 c.57C>G synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 1.0 rifampicin
rpoA 3878461 p.Asp16Gly missense_variant 1.0 rifampicin
rpoA 3878465 p.Thr15Ala missense_variant 1.0 rifampicin
rpoA 3878468 p.Leu14Val missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878472 p.Asp12Glu missense_variant 1.0 rifampicin
rpoA 3878475 c.33G>A synonymous_variant 1.0 rifampicin
rpoA 3878484 c.22_24delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoA 3878490 c.18C>G synonymous_variant 1.0 rifampicin
rpoA 3878493 c.15G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878496 c.12A>G synonymous_variant 1.0 rifampicin
rpoA 3879049 c.-542A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879125 c.-618T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879157 c.-650C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879187 c.-680C>T upstream_gene_variant 1.0 rifampicin
ddn 3986636 c.-208C>A upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986646 c.-198_-196delCTCinsTG upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986661 c.-183_-181delCAGinsAA upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986664 c.-180_-179delAGinsTC upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986673 c.-171C>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986681 c.-163C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986696 c.-148G>C upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986699 c.-145C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986705 c.-139C>G upstream_gene_variant 1.0 delamanid
pretomanid
clpC1 4038238 p.Thr823Ala missense_variant 1.0 pyrazinamide
clpC1 4038243 p.Thr821Ser missense_variant 1.0 pyrazinamide
clpC1 4038262 p.Asp815Asn missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2433T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038307 p.Val800Ile missense_variant 1.0 pyrazinamide
clpC1 4038310 p.Val799Leu missense_variant 1.0 pyrazinamide
clpC1 4038311 c.2394G>A synonymous_variant 0.97 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038325 p.Val794Ile missense_variant 1.0 pyrazinamide
clpC1 4038329 p.Glu792Asp missense_variant 1.0 pyrazinamide
clpC1 4038335 c.2370C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038380 c.2325C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038519 p.Arg729Ala missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 1.0 pyrazinamide
clpC1 4038541 c.2164C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038617 c.2088G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038620 p.Gln695Leu missense_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038659 c.2046C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038743 c.1962G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038794 c.1909_1911delAGCinsTCG synonymous_variant 1.0 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038928 c.1777C>A synonymous_variant 1.0 pyrazinamide
clpC1 4038929 c.1776G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039001 c.1702_1704delAACinsGG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039031 c.1674T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039073 c.1632C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.99 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.99 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.99 pyrazinamide
clpC1 4039115 c.1590G>A synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
clpC1 4039121 c.1584T>G synonymous_variant 0.99 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.99 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039262 c.1443C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039271 c.1434G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039281 p.Val475Ala missense_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039343 c.1362G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039576 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039581 p.Thr375Ser missense_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039693 c.1012C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039697 c.1008C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039727 c.978C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039763 c.942C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039802 c.903G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039855 c.850C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039883 c.822G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039916 c.789T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039997 c.708C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040015 c.690G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040030 c.675C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040039 c.666G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040063 c.642G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040090 c.615T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040093 c.612C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040126 c.579C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040156 p.Met183Ala missense_variant 1.0 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040192 c.513C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040213 c.492T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040255 c.448_450delGCCinsAG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040314 c.391C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040315 p.Glu130Asp missense_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040342 c.363C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040351 c.354C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040360 c.345G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040414 c.291G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040441 c.262_264delCTCinsTG frameshift_variant&synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040447 c.258G>A synonymous_variant 0.89 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040513 c.192G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>A synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040540 c.165G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040546 c.159G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040567 c.138C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040576 c.129C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040582 c.123G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040585 c.120A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040657 c.48T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040666 c.39C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040669 c.36C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040708 c.-4A>G upstream_gene_variant 1.0 pyrazinamide
clpC1 4040727 c.-23T>C upstream_gene_variant 1.0 pyrazinamide
clpC1 4040733 c.-29C>A upstream_gene_variant 1.0 pyrazinamide
clpC1 4040735 c.-31T>G upstream_gene_variant 1.0 pyrazinamide
panD 4044024 c.258T>C synonymous_variant 1.0 pyrazinamide
panD 4044039 c.243G>C synonymous_variant 1.0 pyrazinamide
panD 4044042 c.240T>C synonymous_variant 1.0 pyrazinamide
panD 4044050 c.232T>C synonymous_variant 1.0 pyrazinamide
panD 4044051 c.231C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044057 c.225C>A synonymous_variant 1.0 pyrazinamide
panD 4044063 c.219T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044072 c.210C>G synonymous_variant 1.0 pyrazinamide
panD 4044075 c.207T>C synonymous_variant 1.0 pyrazinamide
panD 4044078 c.204G>C synonymous_variant 1.0 pyrazinamide
panD 4044084 c.198T>C synonymous_variant 1.0 pyrazinamide
panD 4044087 c.195C>T synonymous_variant 0.97 pyrazinamide
panD 4044095 p.Glu63Lys missense_variant 1.0 pyrazinamide
panD 4044120 c.162A>G synonymous_variant 1.0 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 1.0 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 1.0 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 1.0 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 1.0 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 1.0 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 1.0 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044204 c.78G>C synonymous_variant 1.0 pyrazinamide
panD 4044962 c.-681C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044974 c.-693C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044977 c.-696T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 1.0 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044995 c.-714A>G upstream_gene_variant 1.0 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045025 c.-744C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045040 c.-760_-759delTGinsCA upstream_gene_variant 1.0 pyrazinamide
panD 4045052 c.-771G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045055 c.-774T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045058 c.-777G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045063 c.-782T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045064 c.-783G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045073 c.-792C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 1.0 pyrazinamide
glpK 4138451 c.1305T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138457 p.Asp433Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138464 p.Gly431Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138484 c.1272G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138490 c.1266G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138493 c.1261_1263delCAGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138500 p.Arg419His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138529 p.Val409Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138532 c.1224G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138544 p.Gln404Arg missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138587 p.Asn390Ser missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138601 c.1155G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138617 p.Ala380Val missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138619 c.1137C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240736 p.Ser292Ala missense_variant 1.0 ethambutol
embC 4240771 c.909G>C synonymous_variant 1.0 ethambutol
embC 4240777 c.915G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>G synonymous_variant 1.0 ethambutol
embC 4240825 c.963G>A synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240867 c.1005T>A synonymous_variant 1.0 ethambutol
embC 4240870 c.1008T>C synonymous_variant 1.0 ethambutol
embC 4240873 c.1011C>G synonymous_variant 1.0 ethambutol
embC 4240875 p.Ser338Thr missense_variant 1.0 ethambutol
embC 4240879 c.1017G>C synonymous_variant 1.0 ethambutol
embC 4240882 c.1020C>G synonymous_variant 1.0 ethambutol
embC 4240885 c.1023T>C synonymous_variant 1.0 ethambutol
embC 4240897 c.1035C>G synonymous_variant 1.0 ethambutol Not assoc w R
embC 4240900 c.1038A>G synonymous_variant 1.0 ethambutol
embC 4240903 c.1041C>G synonymous_variant 1.0 ethambutol
embC 4240911 p.Ala350Val missense_variant 1.0 ethambutol
embC 4240921 c.1059C>G synonymous_variant 1.0 ethambutol
embC 4240924 c.1062C>G synonymous_variant 1.0 ethambutol
embC 4240934 c.1072_1074delGTAinsCG frameshift_variant&missense_variant 1.0 ethambutol
embC 4240945 c.1083T>G synonymous_variant 1.0 ethambutol
embC 4240957 c.1095C>G synonymous_variant 1.0 ethambutol
embC 4240966 c.1104G>C synonymous_variant 1.0 ethambutol
embC 4240969 c.1107C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240978 c.1116G>A synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embC 4240979 c.1117_1119delACGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embC 4240990 c.1128A>G synonymous_variant 1.0 ethambutol
embC 4240996 c.1134G>C synonymous_variant 1.0 ethambutol
embC 4241002 c.1140G>C synonymous_variant 1.0 ethambutol
embC 4241008 c.1146G>C synonymous_variant 1.0 ethambutol
embC 4241018 c.1156C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241023 c.1161T>G synonymous_variant 1.0 ethambutol
embC 4241024 p.Val388Phe missense_variant 1.0 ethambutol
embC 4241036 c.1174_1176delCTGinsTC frameshift_variant&missense_variant 1.0 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241047 c.1185C>G synonymous_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241056 c.1194C>G synonymous_variant 1.0 ethambutol
embC 4241080 c.1218C>T synonymous_variant 1.0 ethambutol
embC 4241089 c.1227C>G synonymous_variant 1.0 ethambutol
embC 4241125 c.1263G>A synonymous_variant 1.0 ethambutol
embC 4241135 p.Val425Leu missense_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241158 c.1296T>A synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241167 c.1305C>G synonymous_variant 1.0 ethambutol
embC 4241173 c.1311C>T synonymous_variant 1.0 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 1.0 ethambutol
embC 4242928 c.3066A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4242940 c.-293T>C upstream_gene_variant 1.0 ethambutol
embC 4242941 p.His1027Asn missense_variant 1.0 ethambutol
embA 4242946 c.-287T>C upstream_gene_variant 1.0 ethambutol
embA 4242952 c.-281T>C upstream_gene_variant 1.0 ethambutol
embA 4242955 c.-278C>T upstream_gene_variant 1.0 ethambutol
embA 4242961 c.-272G>C upstream_gene_variant 1.0 ethambutol
embA 4242964 c.-269C>G upstream_gene_variant 1.0 ethambutol
embA 4242973 c.-260G>A upstream_gene_variant 1.0 ethambutol
embC 4242980 p.Met1040Val missense_variant 1.0 ethambutol
embA 4242985 c.-248C>G upstream_gene_variant 1.0 ethambutol
embA 4242988 c.-245A>C upstream_gene_variant 1.0 ethambutol
embC 4242990 p.Thr1043Ser missense_variant 1.0 ethambutol
embA 4242994 c.-239G>C upstream_gene_variant 1.0 ethambutol
embC 4242998 p.Ala1046Pro missense_variant 1.0 ethambutol
embC 4243023 p.Phe1054Tyr missense_variant 1.0 ethambutol
embA 4243025 c.-208A>C upstream_gene_variant 1.0 ethambutol
embC 4243040 c.3178_3180delTTAinsCG frameshift_variant&missense_variant 1.0 ethambutol
embA 4243057 c.-176T>G upstream_gene_variant 1.0 ethambutol
embB 4247371 c.858C>G synonymous_variant 1.0 ethambutol
embB 4247384 c.871_873delCATinsTC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247389 c.876C>G synonymous_variant 1.0 ethambutol
embB 4247395 c.882C>G synonymous_variant 1.0 ethambutol
embB 4247398 c.885G>C synonymous_variant 1.0 ethambutol
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247428 c.915C>G synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247462 c.949_950delTCinsAG synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247476 c.963C>G synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247857 c.1344C>G synonymous_variant 1.0 ethambutol
embB 4247893 c.1380C>G synonymous_variant 1.0 ethambutol
embB 4247896 c.1383G>C synonymous_variant 1.0 ethambutol
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247909 c.1396T>C synonymous_variant 1.0 ethambutol
embB 4247920 c.1407T>G synonymous_variant 1.0 ethambutol
embB 4247923 c.1410T>C synonymous_variant 1.0 ethambutol
embB 4247926 c.1413C>G synonymous_variant 1.0 ethambutol
embB 4247928 p.Leu472Gln missense_variant 1.0 ethambutol
embB 4247938 c.1425G>C synonymous_variant 1.0 ethambutol
embB 4247940 p.Leu476Trp missense_variant 1.0 ethambutol
embB 4247945 c.1432T>C synonymous_variant 1.0 ethambutol
embB 4247951 p.Ser480Ala missense_variant 1.0 ethambutol
embB 4247957 c.1444_1446delATGinsTC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247977 c.1464C>G synonymous_variant 1.0 ethambutol
embB 4247978 c.1465_1467delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248052 c.1539G>A synonymous_variant 1.0 ethambutol
embB 4248064 c.1551G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248069 p.Tyr519Trp missense_variant 1.0 ethambutol
embB 4248076 c.1563G>A synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 1.0 ethambutol
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248098 p.Ile529Phe missense_variant 1.0 ethambutol
embB 4248127 c.1614G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248133 c.1620C>G synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248149 c.1636_1638delACCinsGA frameshift_variant&missense_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248181 p.Ile556Met missense_variant 1.0 ethambutol
embB 4248182 p.Met557Leu missense_variant 1.0 ethambutol
embB 4248199 c.1686A>G synonymous_variant 1.0 ethambutol
embB 4248200 c.1687_1689delATTinsGG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248203 p.Pro564Ala missense_variant 1.0 ethambutol
embB 4248206 c.1693_1695delAGCinsGG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248226 c.1713G>C synonymous_variant 1.0 ethambutol
embB 4248238 p.Met575Ile missense_variant 1.0 ethambutol
embB 4248241 c.1728C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248253 c.1740C>T synonymous_variant 1.0 ethambutol
embB 4248265 c.1752C>T synonymous_variant 1.0 ethambutol
embB 4248266 c.1753C>T synonymous_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248295 c.1782C>T synonymous_variant 1.0 ethambutol
embB 4248425 c.1912T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 1.0 ethambutol
embB 4248472 c.1959T>G synonymous_variant 1.0 ethambutol
embB 4248484 c.1971C>T synonymous_variant 1.0 ethambutol
embB 4248485 c.1972_1974delAGCinsTCG synonymous_variant 1.0 ethambutol
embB 4248497 p.Lys662Arg missense_variant 1.0 ethambutol
embB 4248504 p.Asp664Ala missense_variant 1.0 ethambutol
embB 4248508 c.1995G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248514 c.2001A>C synonymous_variant 1.0 ethambutol
embB 4248523 c.2010A>G synonymous_variant 1.0 ethambutol
embB 4248524 c.2011_2013delATCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248535 c.2022C>G synonymous_variant 1.0 ethambutol
embB 4248536 c.2023C>T synonymous_variant 1.0 ethambutol
embB 4248541 c.2028T>C synonymous_variant 1.0 ethambutol
embB 4248556 c.2043C>G synonymous_variant 1.0 ethambutol
embB 4248569 c.2056_2058delCTGinsTA frameshift_variant&stop_gained 1.0 ethambutol
embB 4249483 c.2970C>G synonymous_variant 1.0 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249487 c.2974T>C synonymous_variant 1.0 ethambutol
embB 4249492 c.2979C>G synonymous_variant 1.0 ethambutol
embB 4249525 c.3012T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 1.0 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4249535 c.3022_3024delGAAinsCG frameshift_variant&missense_variant 1.0 ethambutol
embB 4249552 c.3039C>G synonymous_variant 1.0 ethambutol
embB 4249558 c.3045A>C synonymous_variant 1.0 ethambutol
embB 4249568 c.3055_3057delTCGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embB 4249573 c.3060T>C synonymous_variant 1.0 ethambutol
embB 4249576 c.3063G>A synonymous_variant 1.0 ethambutol
embB 4249581 p.Leu1023Gln missense_variant 1.0 ethambutol
embB 4249594 c.3081G>C synonymous_variant 1.0 ethambutol
embB 4249600 c.3087A>G synonymous_variant 1.0 ethambutol
embB 4249608 p.Thr1032Ile missense_variant 1.0 ethambutol
embB 4249624 c.3111C>G synonymous_variant 1.0 ethambutol
embB 4249627 c.3114G>C synonymous_variant 1.0 ethambutol
embB 4249640 c.3127T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267136 c.1701A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267156 p.Gln561Glu missense_variant 1.0 ethambutol
aftB 4267157 c.1678_1680delACGinsGC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
aftB 4267172 c.1665C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
aftB 4267175 c.1660_1662delATCinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
aftB 4267184 c.1653C>G synonymous_variant 1.0 ethambutol
aftB 4267187 c.1650T>C synonymous_variant 1.0 ethambutol
aftB 4267211 c.1626C>G synonymous_variant 1.0 ethambutol
aftB 4267214 c.1623A>G synonymous_variant 1.0 ethambutol
aftB 4267241 c.1596G>C synonymous_variant 1.0 ethambutol
aftB 4267244 c.1593T>C synonymous_variant 1.0 ethambutol
aftB 4267253 c.1584T>C synonymous_variant 1.0 ethambutol
aftB 4267262 c.1575T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4267266 p.Ala524Gly missense_variant 1.0 ethambutol
aftB 4267268 c.1569T>C synonymous_variant 1.0 ethambutol
aftB 4267273 p.Lys522Gln missense_variant 1.0 ethambutol
ubiA 4269149 c.684_685insACG conservative_inframe_insertion 1.0 ethambutol
ubiA 4269159 c.673_675delTCGinsGC frameshift_variant&missense_variant 1.0 ethambutol
ubiA 4269177 c.657G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269186 c.-350C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269191 p.Ser215Gly missense_variant 1.0 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 1.0 ethambutol
aftB 4269207 c.-371G>C upstream_gene_variant 1.0 ethambutol
aftB 4269210 c.-374G>A upstream_gene_variant 1.0 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 1.0 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269225 c.-389C>G upstream_gene_variant 1.0 ethambutol
aftB 4269234 c.-398A>G upstream_gene_variant 1.0 ethambutol
aftB 4269240 c.-404G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269243 p.His197Gln missense_variant 1.0 ethambutol
aftB 4269264 c.-428C>T upstream_gene_variant 1.0 ethambutol
ubiA 4269271 p.Val188Ala missense_variant 1.0 ethambutol Uncertain significance
aftB 4269285 c.-449T>G upstream_gene_variant 1.0 ethambutol
aftB 4269540 c.-704C>G upstream_gene_variant 1.0 ethambutol
aftB 4269549 c.-713C>A upstream_gene_variant 1.0 ethambutol
ubiA 4269569 p.Phe89Leu missense_variant 1.0 ethambutol
aftB 4269572 c.-736A>C upstream_gene_variant 1.0 ethambutol
ubiA 4269578 p.Thr86Ala missense_variant 1.0 ethambutol
ubiA 4269582 c.252C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
ubiA 4269585 p.Glu83Ala missense_variant 1.0 ethambutol
aftB 4269594 c.-758A>C upstream_gene_variant 1.0 ethambutol
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
ubiA 4269609 p.Val75Ala missense_variant 1.0 ethambutol Uncertain significance
aftB 4269612 c.-776T>C upstream_gene_variant 1.0 ethambutol
aftB 4269621 c.-785C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269632 p.Ala68Ser missense_variant 1.0 ethambutol
aftB 4269633 c.-797G>A upstream_gene_variant 1.0 ethambutol
aftB 4269639 c.-803C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269647 p.Ser63Cys missense_variant 1.0 ethambutol
aftB 4269660 c.-824C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269663 p.Met57Ile missense_variant 1.0 ethambutol
ubiA 4269670 p.Val55Ala missense_variant 1.0 ethambutol Uncertain significance
ubiA 4269676 p.Ser53Leu missense_variant 1.0 ethambutol
aftB 4269678 c.-842C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269684 p.Glu50Asp missense_variant 1.0 ethambutol
ubiA 4269688 p.Val49Ala missense_variant 1.0 ethambutol Uncertain significance
ubiA 4269700 p.Arg45His missense_variant 1.0 ethambutol
aftB 4269702 c.-866C>G upstream_gene_variant 1.0 ethambutol
aftB 4269705 c.-869T>C upstream_gene_variant 1.0 ethambutol
ubiA 4269710 p.Gly42Arg missense_variant 1.0 ethambutol
aftB 4269716 c.-880T>C upstream_gene_variant 1.0 ethambutol
aftB 4269720 c.-884C>G upstream_gene_variant 1.0 ethambutol
aftB 4269729 c.-893G>C upstream_gene_variant 1.0 ethambutol
aftB 4269768 c.-932C>A upstream_gene_variant 1.0 ethambutol
ubiA 4269771 c.61_63delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol
ubiA 4269782 p.Val18Ile missense_variant 1.0 ethambutol
ethA 4326232 c.1242T>C synonymous_variant 1.0 ethionamide
ethA 4326235 c.1239T>A synonymous_variant 1.0 ethionamide
ethA 4326240 p.Asn412His missense_variant 1.0 ethionamide
ethA 4326253 c.1221T>C synonymous_variant 1.0 ethionamide
ethA 4326258 c.1216T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
ethA 4326261 p.Leu405Val missense_variant 1.0 ethionamide
ethA 4326262 c.1212C>G synonymous_variant 1.0 ethionamide
ethA 4326265 c.1209T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
ethA 4326271 c.1203T>C synonymous_variant 1.0 ethionamide
ethA 4326304 c.1170C>G synonymous_variant 1.0 ethionamide
ethA 4326307 c.1167C>G synonymous_variant 1.0 ethionamide
ethA 4326310 c.1164T>C synonymous_variant 1.0 ethionamide
ethA 4326325 c.1149G>C synonymous_variant 1.0 ethionamide
ethA 4326329 p.Tyr382Phe missense_variant 1.0 ethionamide
ethA 4326331 c.1143C>G synonymous_variant 1.0 ethionamide
ethA 4326340 c.1134C>G synonymous_variant 1.0 ethionamide
ethA 4326343 p.Ile377Met missense_variant 1.0 ethionamide
ethA 4326346 c.1128C>G synonymous_variant 1.0 ethionamide
ethA 4326351 p.Ser375Thr missense_variant 1.0 ethionamide
ethA 4326352 c.1122T>G synonymous_variant 1.0 ethionamide