TB-Profiler result

Run: ERR176560

Summary

Run ID: ERR176560

Sample name:

Date: 2024-04-16T01:59:37.893397

Number of reads: 1095390

Percentage reads mapped: 16.7

Median coverage: 16.0

Strain: La1.7;lineage4.9

Spoligotype:

Drug-resistance: HR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.1.2 Indo-Oceanic RD239 0.18
La1.7 M.bovis None 0.33
lineage4.9 Euro-American (H37Rv-like) None 0.73
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ala379Val Uncertain significance Mutation from literature
p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide ethA c.478_480delCCGinsAC Assoc w R
c.85_87delACCinsTG Assoc w R
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.421_423delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.760_762delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.610_612delCTCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1549_1551delCTTinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1756_1758delGACinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
ddn c.220_222delATTinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491203 c.421_423delCAGinsGA frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491542 c.760_762delTTGinsCA frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303540 c.610_612delCTCinsTG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304479 c.1549_1551delCTTinsTG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304686 c.1756_1758delGACinsCA frameshift_variant&missense_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2154976 p.Ala379Val missense_variant 1.0 isoniazid Uncertain significance Mutation from literature
katG 2155108 p.Ile335Thr missense_variant 0.98 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.92 isoniazid Assoc w R High-level resistance
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
ddn 3987063 c.220_222delATTinsGC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
ethA 4326994 c.478_480delCCGinsAC frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4327387 c.85_87delACCinsTG frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 645 c.645A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 657 c.657C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 666 c.666C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>A synonymous_variant 1.0 isoniazid
dnaA 682 c.682T>C synonymous_variant 1.0 isoniazid
dnaA 687 c.687C>T synonymous_variant 0.52 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.44 isoniazid
dnaA 693 c.693A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 699 c.699G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 744 c.744C>T synonymous_variant 1.0 isoniazid
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 753 c.753C>T synonymous_variant 1.0 isoniazid
dnaA 759 c.759C>T synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 780 c.780C>G synonymous_variant 1.0 isoniazid
dnaA 783 c.783C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 867 c.867C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 873 c.873C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 990 c.990A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.9 isoniazid
dnaA 999 c.999C>G synonymous_variant 0.9 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 0.92 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.96 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.96 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.96 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.98 isoniazid
dnaA 1053 c.1053C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1056 c.1056G>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 0.98 isoniazid
dnaA 1065 c.1065C>T synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.98 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.98 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.98 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 0.98 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1126 c.1126C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1203 c.1203T>C synonymous_variant 0.88 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.95 isoniazid
dnaA 1223 p.Thr408Ile missense_variant 0.92 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>G synonymous_variant 0.93 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 0.95 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.95 isoniazid
dnaA 1275 c.1275C>T synonymous_variant 0.95 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.95 isoniazid
dnaA 1308 c.1308G>A synonymous_variant 0.93 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.91 isoniazid
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6151 c.912C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6181 c.942C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6187 c.948C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6208 c.969G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6343 c.-959G>A upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6349 c.-953G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6355 c.-947G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6448 c.-854G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6452 p.Val405Thr missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 6457 c.-845T>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6460 c.-842G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>A upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6487 c.1248C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6490 c.-812T>G upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 6493 c.-809C>T upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6502 c.-800T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6515 c.-787T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6542 c.1303_1305delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312_1314delTTGinsCA frameshift_variant&missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrA 6556 c.-746C>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6592 c.-710C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6679 c.-623G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6685 c.-617C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6787 c.-515G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6817 c.1578G>A synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6850 c.-452C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6877 c.1638G>A synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6878 c.1639T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6950 c.1711_1713delCTCinsTG frameshift_variant&missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6997 c.-305G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7018 c.-284G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7057 c.-245C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7174 c.-128C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7192 c.-110G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 7198 c.1959C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7379 c.78C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7430 c.129G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7461 c.160C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7574 c.273G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7643 c.342C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7655 c.354G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7688 c.387C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7758 p.Ile153Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7808 c.507G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7850 c.549C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7881 c.580C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8231 c.930C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8252 c.951G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8357 c.1056G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8385 c.1084_1086delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8408 c.1107A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8537 c.1236G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8580 p.Ile427Val missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8597 c.1296C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8637 c.1336C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8664 c.1363C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8684 c.1383G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8705 c.1404C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8706 c.1405C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8766 c.1465_1467delAGGinsCA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8783 c.1482G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8789 c.1488C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 c.1495_1497delATCinsGG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8835 p.Ala512Thr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8843 c.1542G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8912 c.1611G>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.99 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9047 c.1746C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9086 c.1785C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9104 c.1803C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9140 c.1839G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9365 p.Glu688Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9369 c.2068C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9389 c.2088C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9421 p.Ile707Thr missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Tyr missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9455 c.2154T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9464 c.2163C>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9476 c.2175G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9659 c.2358C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9665 c.2364A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9677 c.2376C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9683 c.2382G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9695 c.2394C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9698 c.2397G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9717 c.2416C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9737 c.2436G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9740 c.2439G>A synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 490818 c.36C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490839 c.57G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491154 c.372G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491250 c.468G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491256 c.474G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.99 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491319 c.537G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491478 c.696G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491490 c.708C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491500 p.Glu240Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 p.Glu292Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574688 c.-660G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574712 c.-636A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574715 c.-633C>G upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574742 c.-606G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574752 c.-596T>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574763 c.-585T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574766 c.-582T>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574769 c.-579C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>T synonymous_variant 0.96 ethionamide
isoniazid
mshA 575665 c.318G>T synonymous_variant 0.96 ethionamide
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575701 c.354G>A synonymous_variant 0.93 ethionamide
isoniazid
mshA 575704 c.357T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 0.88 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575713 c.366G>A synonymous_variant 0.92 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.93 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575749 c.402C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.96 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 0.96 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575818 c.471G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575837 c.490C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575860 c.513G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575875 c.528C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575923 c.576C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575929 c.582C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575939 c.592C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575947 c.600G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575974 c.627G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575977 c.630G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 1.0 ethionamide
isoniazid
ccsA 619594 c.-297G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-256delTCinsGT upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619648 c.-243C>G upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>C upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236_-235delATinsGC upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619658 c.-233A>G upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619673 c.-218C>T upstream_gene_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 619766 c.-125A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619771 c.-120C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619774 c.-117C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619786 c.-105G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619794 c.-97_-96delCCinsAT upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619798 c.-93G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619810 c.-81G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620379 c.489G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620647 p.Glu253Gln missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620658 c.768C>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620670 c.780C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620692 c.802_804delTCCinsGT frameshift_variant&missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>A synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>T synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAA frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620802 c.912C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620832 c.942C>A synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620847 c.957G>A synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620856 c.966C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
Rv0565c 656244 c.1227A>G synonymous_variant 1.0 ethionamide
Rv0565c 656247 c.1224A>G synonymous_variant 1.0 ethionamide
Rv0565c 656259 c.1212G>C synonymous_variant 1.0 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 1.0 ethionamide
Rv0565c 656277 c.1194C>T synonymous_variant 1.0 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 1.0 ethionamide
Rv0565c 656292 c.1177_1179delGCGinsTC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656298 c.1173G>C synonymous_variant 1.0 ethionamide
Rv0565c 656304 c.1167T>G synonymous_variant 1.0 ethionamide
Rv0565c 656307 c.1164G>C synonymous_variant 1.0 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 1.0 ethionamide
Rv0565c 656334 c.1137A>G synonymous_variant 0.98 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656511 c.960T>C synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656538 p.Ser311Glu missense_variant 0.93 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 0.93 ethionamide
Rv0565c 656547 c.924C>G synonymous_variant 0.93 ethionamide
Rv0565c 656551 p.Asn307Val missense_variant 0.93 ethionamide
Rv0565c 656556 c.915G>C synonymous_variant 0.93 ethionamide Not assoc w R - Interim
Rv0565c 656562 c.909C>G synonymous_variant 1.0 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 1.0 ethionamide
Rv0565c 656571 c.900C>A synonymous_variant 0.93 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 1.0 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 1.0 ethionamide
Rv0565c 657138 c.331_333delGCAinsTG frameshift_variant&missense_variant 0.93 ethionamide Uncertain significance
Rv0565c 657144 c.327T>C synonymous_variant 0.94 ethionamide
Rv0565c 657147 c.324C>T synonymous_variant 0.9 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 0.93 ethionamide
Rv0565c 657187 p.His95Arg missense_variant 0.95 ethionamide
Rv0565c 657189 c.282C>A synonymous_variant 0.95 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.95 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.95 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 0.96 ethionamide Uncertain significance
Rv0565c 657210 c.261C>T synonymous_variant 0.97 ethionamide Not assoc w R - Interim
Rv0565c 657220 p.Ala84Val missense_variant 0.97 ethionamide
Rv0565c 657231 c.238_240delATCinsGT frameshift_variant&missense_variant 0.97 ethionamide Uncertain significance
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.94 ethionamide Uncertain significance
Rv0565c 657264 c.207T>C synonymous_variant 1.0 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 1.0 ethionamide
Rv0565c 657272 c.199C>T synonymous_variant 1.0 ethionamide
Rv0565c 657273 c.198G>C synonymous_variant 1.0 ethionamide
Rv0565c 657294 c.177C>G synonymous_variant 1.0 ethionamide
Rv0565c 657297 c.174G>C synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 0.96 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657611 c.-141C>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 0.94 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.94 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.96 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.96 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 0.97 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 0.97 ethionamide
Rv0565c 657662 c.-192C>T upstream_gene_variant 0.97 ethionamide
Rv0565c 657683 c.-213C>G upstream_gene_variant 0.98 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.98 ethionamide
Rv0565c 657730 c.-260A>G upstream_gene_variant 0.99 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.99 ethionamide
hadA 731738 c.-192G>C upstream_gene_variant 1.0 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 1.0 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 1.0 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.99 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 731861 c.-69G>C upstream_gene_variant 1.0 isoniazid
nusG 734073 c.-181_-179delGTTinsAC upstream_gene_variant 1.0 rifampicin
nusG 734082 c.-172A>C upstream_gene_variant 1.0 rifampicin
nusG 734087 c.-167G>C upstream_gene_variant 1.0 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 1.0 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 1.0 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 1.0 rifampicin
nusG 734118 c.-136_-134delCTTinsAG upstream_gene_variant 1.0 rifampicin
nusG 734135 c.-119G>A upstream_gene_variant 1.0 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.95 rifampicin
nusG 734418 c.165C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734421 c.168A>C synonymous_variant 0.97 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.97 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.98 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.99 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.99 rifampicin
nusG 734466 c.213G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.99 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.99 rifampicin
nusG 734614 c.361_363delGCCinsTG frameshift_variant&missense_variant 0.98 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.98 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.97 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.97 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.95 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734661 c.408A>C synonymous_variant 0.93 rifampicin
nusG 734664 c.411T>G synonymous_variant 0.93 rifampicin
nusG 734805 c.552C>T synonymous_variant 1.0 rifampicin
nusG 734811 c.558G>A synonymous_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734832 c.579C>G synonymous_variant 1.0 rifampicin
nusG 734844 c.591G>A synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>G synonymous_variant 1.0 rifampicin
nusG 734863 p.Thr204Ser missense_variant 1.0 rifampicin
nusG 734889 c.636G>A synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734934 c.681G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734937 c.684G>C synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734950 p.Gly233Asn missense_variant 1.0 rifampicin
nusG 734955 c.702A>G synonymous_variant 1.0 rifampicin
nusG 734961 c.708C>G synonymous_variant 1.0 rifampicin
rpoB 759571 c.-236C>A upstream_gene_variant 1.0 rifampicin
rpoB 759604 c.-203A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759606 c.-201T>C upstream_gene_variant 1.0 rifampicin
rpoB 759635 c.-172C>T upstream_gene_variant 1.0 rifampicin
rpoB 759643 c.-164T>C upstream_gene_variant 1.0 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759655 c.-152_-150delCAGinsA upstream_gene_variant 1.0 rifampicin
rpoB 759659 c.-148T>C upstream_gene_variant 1.0 rifampicin
rpoB 759661 c.-146G>C upstream_gene_variant 1.0 rifampicin
rpoB 759662 c.-145C>T upstream_gene_variant 1.0 rifampicin
rpoB 759672 c.-135G>A upstream_gene_variant 1.0 rifampicin
rpoB 759674 c.-133T>C upstream_gene_variant 1.0 rifampicin
rpoB 759678 c.-129T>C upstream_gene_variant 1.0 rifampicin
rpoB 759706 c.-101T>C upstream_gene_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760085 c.279C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760115 c.309C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 760118 c.312T>A synonymous_variant 1.0 rifampicin
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760148 c.342C>T synonymous_variant 0.97 rifampicin
rpoB 760163 c.357G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>A synonymous_variant 0.99 rifampicin
rpoB 760253 c.447T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>G synonymous_variant 0.98 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.99 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.96 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.99 rifampicin
rpoB 760357 p.Thr184Ser missense_variant 0.99 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.99 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760388 c.582C>T synonymous_variant 1.0 rifampicin
rpoB 760389 c.583_585delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 760394 c.588C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760527 p.Gln241Ala missense_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>T synonymous_variant 1.0 rifampicin
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760608 c.802C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760697 c.891G>A synonymous_variant 1.0 rifampicin
rpoB 760718 c.912C>A synonymous_variant 0.98 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760796 c.990A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>A synonymous_variant 1.0 rifampicin
rpoB 760829 c.1023C>G synonymous_variant 1.0 rifampicin
rpoB 760830 c.1024_1026delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760874 c.1068G>A synonymous_variant 1.0 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760922 c.1116G>T synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>T synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761217 c.1411_1413delCCGinsTC frameshift_variant&missense_variant 0.94 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.98 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 0.98 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.99 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.99 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.99 rifampicin
rpoB 761402 c.1596C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761411 c.1605G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761414 c.1608A>C synonymous_variant 1.0 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761437 p.Ala544Asp missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 1.0 rifampicin
rpoB 761451 p.Val549Thr missense_variant 1.0 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761501 c.1695G>C synonymous_variant 1.0 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 1.0 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>A synonymous_variant 1.0 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761655 p.Ala617Arg missense_variant 1.0 rifampicin
rpoB 761672 c.1866C>G synonymous_variant 0.99 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.99 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 1.0 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761727 p.Ser641Gly missense_variant 1.0 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>G synonymous_variant 0.99 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 1.0 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761862 c.2056_2058delGCGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761867 c.2061C>G synonymous_variant 1.0 rifampicin
rpoB 761870 c.2064C>T synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761903 c.2097T>A synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761931 c.2125C>T synonymous_variant 1.0 rifampicin
rpoB 761951 c.2145G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762027 c.2221_2223delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762068 c.2262C>T synonymous_variant 1.0 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>T synonymous_variant 1.0 rifampicin
rpoB 762098 c.2292C>G synonymous_variant 1.0 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762138 c.2332C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 c.2491C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.99 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.99 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>A upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762467 c.-903C>T upstream_gene_variant 1.0 rifampicin
rpoB 762485 c.2679G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 1.0 rifampicin
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.94 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.93 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762590 c.-780C>G upstream_gene_variant 1.0 rifampicin
rpoB 762593 c.2787C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762608 c.-762C>G upstream_gene_variant 1.0 rifampicin
rpoC 762617 c.-753C>G upstream_gene_variant 1.0 rifampicin
rpoC 762710 c.-660G>C upstream_gene_variant 1.0 rifampicin
rpoC 762728 c.-642C>T upstream_gene_variant 1.0 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 1.0 rifampicin
rpoC 762741 c.-629C>T upstream_gene_variant 1.0 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 1.0 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762785 c.-585C>T upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 c.3007_3009delATGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762820 p.Phe1005Tyr missense_variant 1.0 rifampicin
rpoB 762830 c.3024C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.99 rifampicin
rpoC 763079 c.-291C>G upstream_gene_variant 0.99 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>A upstream_gene_variant 0.99 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763157 c.3351G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 0.99 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763220 c.-150G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 1.0 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763373 c.4_6delCTCinsTA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763783 c.414G>C synonymous_variant 1.0 rifampicin
rpoC 763796 p.Met143Leu missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763804 c.435C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763835 c.466_468delGCGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763840 c.471G>C synonymous_variant 1.0 rifampicin
rpoC 763849 c.480G>A synonymous_variant 1.0 rifampicin
rpoC 763852 c.483C>G synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 1.0 rifampicin
rpoC 763906 c.537C>T synonymous_variant 1.0 rifampicin
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>G synonymous_variant 1.0 rifampicin
rpoC 764167 c.798G>A synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764195 p.Ser276Ala missense_variant 1.0 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 0.98 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764255 c.886C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764260 c.891G>A synonymous_variant 0.98 rifampicin
rpoC 764266 c.897T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764272 c.903G>A synonymous_variant 0.96 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.98 rifampicin
rpoC 764285 p.Gly306Thr missense_variant 0.98 rifampicin
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764338 c.969G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.99 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.99 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.99 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.99 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.97 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>A synonymous_variant 1.0 rifampicin
rpoC 764548 c.1179G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764570 c.1203_1204delGC frameshift_variant 1.0 rifampicin
rpoC 764577 c.1208delCinsGAG frameshift_variant&stop_gained&missense_variant 1.0 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764656 c.1287C>G synonymous_variant 1.0 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 1.0 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.99 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.99 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764851 c.1482C>T synonymous_variant 0.99 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.98 rifampicin
rpoC 764878 c.1509C>T synonymous_variant 0.98 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764896 c.1527C>T synonymous_variant 0.99 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.99 rifampicin
rpoC 764932 c.1563C>G synonymous_variant 0.98 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.97 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>A synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>T synonymous_variant 1.0 rifampicin
rpoC 765202 c.1833C>G synonymous_variant 0.94 rifampicin
rpoC 765208 c.1839T>C synonymous_variant 0.94 rifampicin
rpoC 765220 c.1851A>G synonymous_variant 0.95 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 0.95 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 0.95 rifampicin
rpoC 765244 c.1875T>C synonymous_variant 1.0 rifampicin
rpoC 765247 c.1878C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765248 c.1879T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765251 c.1882_1884delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765259 c.1890G>C synonymous_variant 1.0 rifampicin
rpoC 765281 c.1912_1914delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765299 p.Val644Ile missense_variant 1.0 rifampicin
rpoC 765305 c.1936_1938delATCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765311 p.Ala648Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>C synonymous_variant 1.0 rifampicin
rpoC 765350 c.1981_1983delGCGinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765361 c.1992C>G synonymous_variant 1.0 rifampicin
rpoC 765404 c.2035_2037delCTGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>A synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765548 c.2179_2180delAGinsTC synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765590 p.Arg741Gly missense_variant 1.0 rifampicin
rpoC 765596 p.Lys743Gln missense_variant 1.0 rifampicin
rpoC 765611 p.His748Ala missense_variant 1.0 rifampicin
rpoC 765619 c.2250G>A synonymous_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765740 p.Glu791Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765805 c.2436C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>T synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>G synonymous_variant 1.0 rifampicin
rpoC 765871 c.2502T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>G synonymous_variant 0.99 rifampicin
rpoC 765940 c.2571A>G synonymous_variant 0.99 rifampicin
rpoC 765967 c.2598C>G synonymous_variant 0.99 rifampicin
rpoC 765973 c.2604C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765985 c.2616C>T synonymous_variant 0.99 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.98 rifampicin
rpoC 766018 c.2649C>T synonymous_variant 0.98 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.98 rifampicin
rpoC 766034 p.His889Ala missense_variant 0.97 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 0.97 rifampicin
rpoC 766061 p.Val898Thr missense_variant 0.97 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.98 rifampicin
rpoC 766113 p.Tyr915Phe missense_variant 0.98 rifampicin
rpoC 766120 c.2751A>G synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>C synonymous_variant 1.0 rifampicin
rpoC 766138 c.2769G>C synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766166 p.Ala933Lys missense_variant 1.0 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766276 c.2907C>G synonymous_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>G synonymous_variant 0.99 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.99 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.99 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.99 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.98 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.99 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.99 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.99 rifampicin
rpoC 766546 p.Glu1059Asp missense_variant 0.99 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.99 rifampicin
rpoC 766568 p.Val1067Ile missense_variant 0.99 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.99 rifampicin
rpoC 766582 c.3213C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.99 rifampicin
rpoC 766618 c.3249G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766652 p.Ser1095Thr missense_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 1.0 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766678 c.3309C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766687 c.3318G>A synonymous_variant 1.0 rifampicin
rpoC 766688 p.Val1107Leu missense_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766723 c.3354G>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766749 p.Pro1127Gln missense_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766820 p.Asp1151Asn missense_variant 1.0 rifampicin
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766871 p.Ile1168Val missense_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766920 p.Ala1184Gly missense_variant 1.0 rifampicin
rpoC 766933 c.3564A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766942 c.3573C>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767035 c.3666G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767146 c.3777G>C synonymous_variant 1.0 rifampicin
rpoC 767152 c.3783T>G synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767186 p.Gln1273Glu missense_variant 1.0 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767224 c.3855C>T synonymous_variant 1.0 rifampicin
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>A synonymous_variant 1.0 rifampicin
rpsL 781571 c.12C>T synonymous_variant 0.97 streptomycin
rpsL 781592 c.33T>G synonymous_variant 0.98 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.98 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.98 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 0.99 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 0.99 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.99 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.99 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.99 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.99 streptomycin
rpsL 781679 c.120C>G synonymous_variant 0.99 streptomycin
rpsL 781715 c.156T>G synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781724 c.165G>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781779 c.220C>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800209 c.-600C>T upstream_gene_variant 1.0 linezolid
rplC 800216 c.-593A>G upstream_gene_variant 1.0 linezolid
rplC 800219 c.-590T>C upstream_gene_variant 1.0 linezolid
rplC 800221 c.-588T>C upstream_gene_variant 1.0 linezolid
rplC 800225 c.-584T>C upstream_gene_variant 1.0 linezolid
rplC 800230 c.-579C>T upstream_gene_variant 1.0 linezolid
rplC 800244 c.-565A>G upstream_gene_variant 1.0 linezolid
rplC 800252 c.-557C>A upstream_gene_variant 1.0 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 1.0 linezolid
rplC 800278 c.-531A>G upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 0.98 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.98 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.98 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.98 linezolid
rplC 800558 c.-251G>A upstream_gene_variant 0.99 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.99 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.99 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 0.99 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.98 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.98 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.97 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.97 linezolid
rplC 800657 c.-152G>A upstream_gene_variant 0.97 linezolid
rplC 800663 c.-146G>A upstream_gene_variant 0.98 linezolid
rplC 800666 c.-143C>T upstream_gene_variant 0.98 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.98 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.98 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.98 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.98 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.98 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.98 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.98 linezolid
rplC 800726 c.-83G>A upstream_gene_variant 1.0 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800760 c.-49_-47delCTTinsTG upstream_gene_variant 1.0 linezolid
rplC 800765 c.-44G>C upstream_gene_variant 1.0 linezolid
rplC 800798 c.-11_-6delTGGACAinsCTGC upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800815 c.7C>A synonymous_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800832 c.24T>C synonymous_variant 1.0 linezolid
rplC 800841 c.33G>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64_66delAGAinsCC frameshift_variant&missense_variant 1.0 linezolid
rplC 800877 c.69A>G synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800883 c.75G>A synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800922 c.114C>A synonymous_variant 1.0 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800940 c.132C>T synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800955 c.147C>G synonymous_variant 1.0 linezolid
rplC 800962 c.154C>T synonymous_variant 1.0 linezolid
rplC 800967 c.159C>G synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>C synonymous_variant 1.0 linezolid
rplC 800988 c.180C>T synonymous_variant 1.0 linezolid
rplC 801008 p.Thr67Ser missense_variant 1.0 linezolid
rplC 801015 c.207G>A synonymous_variant 1.0 linezolid
rplC 801019 p.Thr71Ser missense_variant 1.0 linezolid
rplC 801024 c.216C>A synonymous_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>A synonymous_variant 1.0 linezolid
rplC 801162 c.354C>G synonymous_variant 1.0 linezolid
rplC 801168 c.360C>T synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801183 c.375C>A synonymous_variant 1.0 linezolid
rplC 801186 c.378C>G synonymous_variant 1.0 linezolid
rplC 801210 c.402T>G synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801222 c.414T>C synonymous_variant 0.99 linezolid
rplC 801231 c.423C>T synonymous_variant 1.0 linezolid
rplC 801243 c.435C>T synonymous_variant 1.0 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801300 c.492C>T synonymous_variant 0.98 linezolid
rplC 801312 c.504G>A synonymous_variant 0.98 linezolid
rplC 801324 c.516T>C synonymous_variant 0.98 linezolid
rplC 801337 p.Val177Thr missense_variant 0.98 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.98 linezolid
rplC 801348 c.540T>G synonymous_variant 0.98 linezolid
rplC 801357 c.549T>C synonymous_variant 0.99 linezolid
rplC 801393 c.585G>A synonymous_variant 1.0 linezolid
rplC 801399 c.591G>C synonymous_variant 1.0 linezolid
rplC 801402 c.594T>G synonymous_variant 1.0 linezolid
rplC 801411 c.603C>A synonymous_variant 1.0 linezolid
rplC 801420 c.612A>G synonymous_variant 0.97 linezolid
rplC 801423 c.615G>C synonymous_variant 0.97 linezolid
rplC 801438 c.630T>C synonymous_variant 0.97 linezolid
rplC 801459 p.Lys217Asn missense_variant 0.91 linezolid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303497 c.567G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303501 c.571C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303698 c.768C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.99 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303758 c.828G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303764 c.834C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303800 c.870G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303824 c.894G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303833 c.903C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304121 c.1191A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304166 c.1236A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>C synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304193 c.1263G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304199 c.1269C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304436 c.1506G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304442 c.1512T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304444 p.Ala505Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304478 c.1548G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304487 c.1557C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304493 c.1563C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304508 p.Glu526Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304517 c.1587C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304553 c.1623C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304556 c.1626C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304622 c.1692C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304628 c.1698G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304631 c.1701C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304706 c.1776C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304730 c.1800C>T synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304739 c.1809C>T synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304798 p.Ala623Gly missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304800 c.1870C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304988 c.2058G>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305018 c.2088C>T synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305021 c.2091C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305037 c.2107C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305201 c.2271G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305210 c.2280G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305219 c.2289T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305336 c.2406T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305348 c.2418C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305351 c.2421G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364649 c.237C>G synonymous_variant 0.96 pyrazinamide
sigE 1364652 c.240C>G synonymous_variant 0.96 pyrazinamide
sigE 1364667 c.255T>C synonymous_variant 0.98 pyrazinamide
sigE 1364673 c.261G>C synonymous_variant 0.98 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.98 pyrazinamide
sigE 1364697 c.285G>C synonymous_variant 0.99 pyrazinamide
sigE 1364703 c.291G>A synonymous_variant 0.99 pyrazinamide
sigE 1364704 c.292C>T synonymous_variant 0.99 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.99 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364748 c.336G>C synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364772 c.360G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364832 c.420C>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 0.98 pyrazinamide
sigE 1364872 p.Ile154Val missense_variant 0.98 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
sigE 1364895 p.Glu161Asp missense_variant 0.97 pyrazinamide
sigE 1364910 c.498G>C synonymous_variant 0.96 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
sigE 1364919 c.507T>C synonymous_variant 0.96 pyrazinamide
sigE 1364952 c.540A>G synonymous_variant 0.91 pyrazinamide
sigE 1364961 c.549A>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 1.0 pyrazinamide
sigE 1365072 c.660G>A synonymous_variant 1.0 pyrazinamide
sigE 1365081 c.669G>T synonymous_variant 1.0 pyrazinamide
sigE 1365084 c.672G>T synonymous_variant 1.0 pyrazinamide
sigE 1365087 c.675A>G synonymous_variant 1.0 pyrazinamide
sigE 1365090 c.678T>C synonymous_variant 1.0 pyrazinamide
sigE 1365096 c.684G>C synonymous_variant 1.0 pyrazinamide
sigE 1365099 c.687A>C synonymous_variant 1.0 pyrazinamide
sigE 1365105 c.693C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1365111 c.699C>A synonymous_variant 1.0 pyrazinamide
sigE 1365117 c.705A>G synonymous_variant 1.0 pyrazinamide
sigE 1365123 c.711G>C synonymous_variant 1.0 pyrazinamide
sigE 1365129 c.717C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
atpE 1460900 c.-145T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460906 c.-139G>A upstream_gene_variant 1.0 bedaquiline
atpE 1460918 c.-127A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460921 c.-124C>T upstream_gene_variant 0.92 bedaquiline
atpE 1460927 c.-118C>G upstream_gene_variant 0.92 bedaquiline
atpE 1460933 c.-112T>C upstream_gene_variant 0.92 bedaquiline
atpE 1460936 c.-109T>C upstream_gene_variant 0.92 bedaquiline
atpE 1460948 c.-97A>C upstream_gene_variant 0.92 bedaquiline
atpE 1460949 c.-96_-94delATTinsGC upstream_gene_variant 0.92 bedaquiline
atpE 1460963 c.-82C>T upstream_gene_variant 0.92 bedaquiline
atpE 1460967 c.-78G>T upstream_gene_variant 0.92 bedaquiline
atpE 1461101 c.57T>G synonymous_variant 0.97 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.98 bedaquiline
atpE 1461134 c.90C>T synonymous_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461179 c.135G>T synonymous_variant 1.0 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.95 bedaquiline
atpE 1461188 c.144G>A synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>T synonymous_variant 1.0 bedaquiline
rrs 1471514 n.-332A>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471517 n.-329T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471521 n.-325T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471529 n.-317G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471532 n.-314G>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471536 n.-310C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471541 n.-305G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471550 n.-296T>A upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471553 n.-293C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471928 n.83T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471930 n.85_89delGGAGAinsTTGCAGGG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471996 n.151C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472027 n.182C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472055 n.211_212delGC non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472055 n.211_212delGC non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216delAinsGT non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216delAinsGT non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.452_453insCTGCCC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472300 n.455C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472301 n.456C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472305 n.461_466delTCTCTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.469_470delAT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473289 n.1444T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445_1446insAA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473658 n.1T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473668 n.11C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473670 n.13A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473701 n.44A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473782 n.125A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473792 n.135C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473877 n.220G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473936 n.279A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474286 n.629_630delCTinsTCCTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474293 n.637_646delCCTCTCCGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474715 n.1058T>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1474952 n.1296delC non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475007 n.1350C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475015 n.1358C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475029 n.1372T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475208 n.1551_1552insA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475212 n.1555A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475217 n.1560T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475430 n.1773_1774delTTinsA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475539 n.1882A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475556 n.1899A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475635 n.1978G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475707 n.2050T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475762 n.2105_2106delGCinsTTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476691 n.3034T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
fabG1 1673473 p.Pro12Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1673499 c.-703T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673502 c.-700C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673505 c.-697A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673548 p.Ala37Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1673565 c.-637G>A upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.99 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.99 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.99 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.99 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.99 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.99 ethionamide
isoniazid
inhA 1673643 c.-559C>G upstream_gene_variant 0.99 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.99 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.99 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.99 ethionamide
isoniazid
inhA 1673709 c.-493C>G