Run ID: SRR29231479
Sample name:
Date: 2025-02-11T13:25:20.946772
Number of reads: 322426
Percentage reads mapped: 58.81
Median coverage: 2.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: RR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.9 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.93 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | rpoB | p.Ser450Asn | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rpoB | 761154 | p.Ser450Asn | missense_variant | 1.0 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 1110 | c.1110T>C | synonymous_variant | 0.91 | isoniazid | |
| dnaA | 1119 | c.1119G>A | synonymous_variant | 0.92 | isoniazid | |
| dnaA | 1126 | c.1126C>T | synonymous_variant | 0.92 | isoniazid | Not assoc w R - Interim |
| dnaA | 1134 | c.1134G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1140 | c.1140C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1143 | c.1143G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1149 | c.1149C>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1152 | c.1152A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1153 | c.1153T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1167 | c.1167A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1176 | c.1176A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1195 | c.1195_1197delCTTinsTTG | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1203 | c.1203T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1220 | p.Asn407Ser | missense_variant | 1.0 | isoniazid | |
| dnaA | 1224 | c.1224C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1230 | c.1230A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1242 | c.1242G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1245 | c.1245G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| gyrB | 6086 | p.Thr283Pro | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6091 | c.852G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6109 | c.870G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6124 | c.885C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6133 | c.894G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6154 | c.915C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6160 | c.921C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6184 | c.945C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6187 | c.948C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6203 | p.Ser322Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6217 | c.978G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6223 | c.984G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6238 | c.999G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6253 | c.1014G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6862 | c.-440C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6869 | c.-433T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6872 | c.-430T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6877 | c.-425G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6919 | c.1680T>C | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6931 | c.1692A>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6955 | c.-347G>A | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6970 | c.-332C>T | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7012 | c.-290G>A | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7018 | c.-284G>C | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7021 | c.-281G>A | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7096 | c.-206G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7114 | c.-188C>G | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>T | upstream_gene_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7153 | c.1914G>C | synonymous_variant | 0.83 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7430 | c.129G>A | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7505 | c.204C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7517 | c.216G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7529 | c.228G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7535 | c.234C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7538 | c.237G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7640 | c.339G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7673 | c.372G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7676 | c.375G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382_384delAGGinsCGA | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7691 | c.390C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7745 | c.444G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7760 | c.459C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7797 | c.496_498delCTAinsTTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7868 | c.567C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7881 | c.580C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8126 | c.825G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8162 | c.861C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8189 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8195 | c.894C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8199 | p.Ser300Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8210 | c.909G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8228 | c.927G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8235 | c.934_936delTTAinsCTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | p.Tyr364His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8447 | c.1146C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8450 | c.1149G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8513 | c.1212C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8531 | c.1230G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8537 | c.1236G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8555 | p.Ala419Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8597 | c.1296C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8600 | c.1299G>A | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8633 | c.1332C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8637 | c.1336C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8792 | c.1491G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8796 | p.Ile499Val | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8882 | c.1581G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8945 | c.1644G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9035 | c.1734G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9044 | c.1743C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9065 | c.1764C>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9083 | c.1782G>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9086 | c.1785C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9092 | c.1791C>G | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCTG | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9116 | c.1815G>A | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491109 | c.327G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491113 | c.331C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491133 | c.351A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491144 | p.Ala121Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491166 | c.384G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491172 | c.390C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491226 | c.444C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491280 | c.498C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491316 | c.534C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491493 | c.711C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491499 | c.717G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491500 | p.Glu240Lys | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491512 | p.Asn244Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491542 | c.760_762delTTGinsCTA | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491548 | p.Ala256Pro | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491563 | c.781_782delAGinsTC | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491603 | p.Ala274Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491646 | c.864G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491649 | c.867C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491661 | c.879C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491667 | c.885A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491673 | c.891A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491676 | c.894T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491679 | c.897A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491688 | c.906A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fgd1 | 491697 | c.915G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| mshA | 575629 | c.282A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575632 | c.285G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575633 | p.Ala96Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575641 | c.294A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575644 | c.297G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575651 | p.Arg102Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575665 | c.318G>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575761 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575770 | c.423G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575772 | p.Val142Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575845 | c.498C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575884 | c.537G>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| ccsA | 620247 | p.Leu119Phe | missense_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620253 | c.363G>C | synonymous_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620257 | p.Ile123Val | missense_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620272 | p.Val128Thr | missense_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620284 | p.Ala132Pro | missense_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620295 | c.405G>C | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620301 | c.411G>A | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620307 | c.417C>G | synonymous_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620317 | p.Val143Leu | missense_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620332 | c.442C>T | synonymous_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620337 | c.447C>G | synonymous_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620346 | c.456C>G | synonymous_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620349 | c.459A>G | synonymous_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620358 | c.468C>G | synonymous_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620433 | c.543C>G | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| ccsA | 620436 | c.546T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620439 | c.549T>C | synonymous_variant | 0.94 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 0.94 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620454 | c.564C>G | synonymous_variant | 0.93 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620460 | c.570T>C | synonymous_variant | 0.91 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620631 | c.741T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620634 | c.744C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620685 | c.795G>A | synonymous_variant | 0.96 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| ccsA | 620688 | c.798G>T | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620692 | p.Ser268Ala | missense_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620697 | c.807C>T | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620698 | p.Val270Ile | missense_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620703 | c.813G>C | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620727 | c.837G>T | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620730 | c.840C>T | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620745 | c.855G>T | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620748 | c.858T>G | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620754 | c.864G>C | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620763 | c.873G>A | synonymous_variant | 0.96 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620781 | c.891C>G | synonymous_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620783 | p.Ala298Val | missense_variant | 0.95 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| Rv0565c | 656085 | c.1386A>G | synonymous_variant | 0.9 | ethionamide | |
| Rv0565c | 656088 | c.1383A>G | synonymous_variant | 0.9 | ethionamide | |
| Rv0565c | 656112 | c.1359C>G | synonymous_variant | 0.9 | ethionamide | |
| Rv0565c | 657189 | c.282C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657192 | p.Met93Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657195 | p.Asp92Glu | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657201 | c.270C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657219 | p.Ala84Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657231 | p.Ile80Val | missense_variant | 0.94 | ethionamide | |
| Rv0565c | 657242 | p.Glu77Lys | missense_variant | 0.94 | ethionamide | |
| Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.93 | ethionamide | |
| Rv0565c | 657267 | p.Ser68Cys | missense_variant | 0.93 | ethionamide | |
| hadA | 731687 | c.-243G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731689 | c.-241A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731694 | c.-236T>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731695 | c.-235C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731698 | c.-232T>G | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731700 | c.-230G>A | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731708 | c.-222G>T | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731711 | c.-219T>C | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731712 | c.-218A>G | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731717 | c.-213T>C | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731753 | c.-177A>G | upstream_gene_variant | 0.97 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731786 | c.-144C>G | upstream_gene_variant | 0.95 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.94 | isoniazid | |
| hadA | 731810 | c.-120G>C | upstream_gene_variant | 0.82 | isoniazid | |
| nusG | 734340 | c.87T>C | synonymous_variant | 0.92 | rifampicin | |
| nusG | 734352 | c.99T>C | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734355 | c.102G>C | synonymous_variant | 0.95 | rifampicin | |
| nusG | 734367 | c.114C>G | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734373 | c.120G>A | synonymous_variant | 0.97 | rifampicin | |
| nusG | 734384 | p.Ser44Thr | missense_variant | 0.97 | rifampicin | |
| nusG | 734407 | p.Val52Ile | missense_variant | 0.98 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 0.98 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734457 | c.204C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734472 | c.219T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734502 | c.249G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760059 | p.Tyr85Asp | missense_variant | 0.92 | rifampicin | |
| rpoB | 760067 | c.261G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760106 | c.300G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760181 | c.375T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760199 | c.393C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760253 | c.447T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760343 | c.537G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.95 | rifampicin | Uncertain significance |
| rpoB | 760382 | c.576G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760388 | c.582C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760389 | c.583_585delAGCinsTCG | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760454 | c.648C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760457 | c.651C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760487 | c.681G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760634 | c.828T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760718 | c.912C>G | synonymous_variant | 0.85 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760844 | p.Gln346His | missense_variant | 1.0 | rifampicin | |
| rpoB | 760845 | p.Thr347Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760869 | p.Val355Ile | missense_variant | 0.98 | rifampicin | Uncertain significance |
| rpoB | 760877 | c.1071G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760916 | c.1110C>A | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760920 | p.Leu372Ile | missense_variant | 0.99 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoB | 760971 | c.1165C>A | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761054 | c.1248G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761072 | c.1266G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761129 | c.1323G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761183 | c.1377T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761204 | c.1398C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761220 | c.1414_1416delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761289 | p.Ser495Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761300 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761318 | c.1512G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761465 | c.1659G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761477 | c.1671C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761482 | p.Ala559Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761502 | p.Pro566Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761516 | c.1710G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761519 | p.Asp571Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761521 | p.Tyr572Phe | missense_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761655 | p.Ala617Arg | missense_variant | 1.0 | rifampicin | |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761682 | c.1876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761705 | c.1899C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761736 | p.Ile644Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761765 | c.1959T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761847 | p.Cys681Arg | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761868 | p.Asp688Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761880 | p.Ala692Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761903 | c.2097T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761931 | c.2125C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761999 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762014 | c.2208C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762038 | c.2232C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762170 | c.2364C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762206 | c.2400C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762233 | c.2427G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762353 | c.2547C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762407 | c.-963G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762410 | c.-960T>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762467 | c.-903C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762488 | c.2682G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762491 | c.2685T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762521 | c.-849C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762581 | c.-789T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762582 | c.-788T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762608 | c.-762C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763373 | c.4_6delCTCinsTTA | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763396 | c.27A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763420 | c.51G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763423 | p.Glu18Asp | missense_variant | 0.94 | rifampicin | Uncertain significance |
| rpoC | 763430 | c.61_63delAGGinsCGT | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763435 | c.66A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763483 | c.114G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763484 | c.115_117delCTTinsTTG | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763621 | c.252C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763657 | c.288G>A | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763669 | c.300C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 763672 | c.303C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 763852 | c.483C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763867 | c.498C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763885 | c.516C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763903 | c.534G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763936 | c.567C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763978 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764002 | c.633C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764024 | c.655_657delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764074 | c.705C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764242 | c.873C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764245 | c.876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764248 | c.879C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764266 | c.897T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764284 | c.915G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764323 | c.954G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764344 | c.975C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764387 | c.1018T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764491 | c.1122G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764572 | c.1203G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764584 | c.1215G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764585 | c.1216_1218delCTCinsTTG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764656 | c.1287C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764767 | c.1398G>A | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764812 | c.1443C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764932 | c.1563C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764947 | c.1578G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765013 | c.1644C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765404 | p.Leu679Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765451 | c.2082C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765454 | c.2085C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765466 | c.2097C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765469 | c.2100G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765493 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765548 | c.2179_2180delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765578 | c.2209C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765596 | p.Lys743Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765727 | c.2358T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766378 | c.3009C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766459 | c.3090G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766469 | c.3100C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766495 | c.3126C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766534 | c.3165C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766564 | c.3195C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766567 | c.3198C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766621 | c.3252G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766624 | c.3255G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766652 | p.Ser1095Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766661 | p.Val1098Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766667 | p.Ser1100Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766700 | c.3331C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766714 | c.3345G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766741 | c.3372G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766771 | c.3402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766775 | p.Arg1136Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766846 | c.3477C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766867 | c.3498C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766900 | c.3531T>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766933 | c.3564A>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 766942 | c.3573C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766957 | c.3588G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766960 | c.3591C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 766978 | c.3609C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766981 | c.3612T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 767158 | c.3789T>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.96 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 767197 | c.3828G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 767203 | c.3834C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 767317 | c.3949_*2522del | stop_lost&conservative_inframe_deletion&splice_region_variant | 0.92 | rifampicin | |
| rpsL | 781128 | c.-432C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781134 | c.-426T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781138 | c.-422_-420delCAGinsGAA | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781143 | c.-417T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781158 | c.-402C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781164 | c.-396T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781173 | c.-387A>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781179 | c.-381T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781185 | c.-375T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781194 | c.-366G>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781197 | c.-363A>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781206 | c.-354C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781209 | c.-351C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781218 | c.-342C>G | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781224 | c.-336T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781230 | c.-330T>C | upstream_gene_variant | 1.0 | streptomycin | |
| rplC | 801312 | c.504G>C | synonymous_variant | 0.88 | linezolid | |
| rplC | 801321 | c.513C>T | synonymous_variant | 0.87 | linezolid | Not assoc w R - Interim |
| rplC | 801324 | c.516T>C | synonymous_variant | 0.93 | linezolid | |
| rplC | 801337 | p.Val177Thr | missense_variant | 0.92 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 0.92 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 0.92 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801366 | c.558T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801369 | c.561C>T | synonymous_variant | 0.92 | linezolid | |
| rplC | 801372 | p.Glu188Asp | missense_variant | 0.92 | linezolid | |
| rplC | 801396 | c.588T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801399 | c.591G>T | synonymous_variant | 0.92 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801411 | c.603C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801413 | p.Thr202Asn | missense_variant | 1.0 | linezolid | |
| rplC | 801420 | c.612A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
| Rv1129c | 1253383 | c.1152A>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253396 | p.Arg380Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253406 | c.1129A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253407 | p.Glu376Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253410 | c.1125A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253416 | c.1119C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| Rv1129c | 1253431 | c.1104C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253476 | c.1059G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253479 | c.1056G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253482 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253485 | c.1050C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253491 | c.1044A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253503 | c.1032C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253506 | c.1029A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253509 | c.1026C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| Rv1129c | 1253518 | c.1017C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303531 | p.Met201Leu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303606 | p.Lys226Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303611 | c.681G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303614 | c.684C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303623 | c.693C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303632 | c.702T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303644 | c.714G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303646 | p.Ala239Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303659 | c.729T>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303662 | c.732C>T | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303681 | c.751T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303686 | c.756C>G | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303701 | c.771C>G | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303713 | c.783C>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303729 | c.799_801delCTAinsTTG | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303732 | p.Ser268Val | missense_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303740 | c.810C>T | synonymous_variant | 0.93 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303746 | p.Asp272Glu | missense_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 0.94 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303761 | c.831T>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303788 | c.858T>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303789 | p.Ile287Val | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303794 | c.864A>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303824 | c.894G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303827 | c.897A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303833 | c.903C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303845 | c.915C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303846 | p.Phe306Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303857 | c.927C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303860 | c.930A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303869 | p.Asp313Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303871 | p.Tyr314Phe | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303878 | c.948G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303884 | c.954T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303890 | c.960G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303905 | c.975G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303914 | c.984C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303953 | p.Asp341Glu | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303969 | p.Val347Ile | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303973 | p.Gly348Ala | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303980 | c.1050G>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304001 | c.1071C>T | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304013 | c.1083G>A | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304694 | c.1764A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304703 | c.1773C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304712 | c.1782C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304755 | c.1825_1827delCTAinsTTG | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304763 | c.1833C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304790 | c.1860C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304798 | p.Ala623Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| sigE | 1364709 | c.297T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364715 | c.303G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364748 | c.336G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364784 | c.372C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364793 | c.381C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364802 | c.390C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364805 | c.393C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364811 | c.399A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364847 | c.435G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364856 | c.444C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364859 | c.447C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364862 | c.450C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364865 | c.453G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364867 | p.Ala152Gly | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364871 | c.459C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364872 | p.Ile154Val | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364886 | c.474G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364889 | c.477A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364895 | p.Glu161Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364907 | c.495G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364913 | c.501C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1460816 | c.-229T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460828 | c.-217C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460831 | c.-214T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460840 | c.-205A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460855 | c.-190T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460858 | c.-187C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460861 | c.-184C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460876 | c.-169G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460882 | c.-163T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460885 | c.-160G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460894 | c.-151A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460900 | c.-145T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460904 | c.-141C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461158 | c.114T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461179 | c.135G>A | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461209 | c.165C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461224 | c.180T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461230 | p.Ala63Met | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461254 | c.210T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461261 | c.217C>T | synonymous_variant | 1.0 | bedaquiline | |
| rrl | 1475088 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475202 | n.1545G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475211 | n.1554G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475212 | n.1555A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476108 | n.2451T>C | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
| linezolid | ||||||
| inhA | 1673547 | c.-655T>C | upstream_gene_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673565 | c.-637G>C | upstream_gene_variant | 0.94 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673574 | c.-628C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673580 | c.-622T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1673589 | c.-613A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673596 | c.-606_-604delAAGinsGAC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673601 | c.-601G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673616 | c.-586A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673619 | c.-583T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673633 | c.-569G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673643 | c.-559C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673646 | c.-556T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673657 | c.-545_-544delCGinsAA | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673660 | c.-542C>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673664 | c.-538A>C | upstream_gene_variant | 0.98 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673667 | c.-535A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673712 | c.-490A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673748 | c.-454A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673755 | c.-447_-445delGAGinsCAA | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673767 | c.-435A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673808 | c.-394A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673816 | c.-386G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673829 | c.-373C>G | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673830 | c.-372_-370delAAAinsCGG | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673838 | c.-364T>C | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673847 | c.-355A>C | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673853 | c.-349A>C | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673862 | c.-340C>G | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673865 | c.-337C>G | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673870 | c.-332G>C | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673916 | c.-286A>C | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673917 | c.-285G>C | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673922 | c.-280T>C | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673940 | c.-262C>T | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673941 | c.-261G>T | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673946 | c.-256C>G | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673949 | c.-253G>A | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673952 | c.-250G>A | upstream_gene_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673961 | c.-241A>C | upstream_gene_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674024 | c.-178T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674037 | c.-165_-164delCAinsGC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674045 | c.-157G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674049 | c.-153C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674054 | c.-148T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674060 | c.-142A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674072 | c.-130C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674079 | c.-123C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674083 | c.-119C>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674096 | c.-106G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674109 | c.-93C>T | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| rpsA | 1833515 | c.-27_-24delCAACinsAAA | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833536 | c.-6_-3delAACAinsCCC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833628 | c.87G>A | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833634 | c.93G>A | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833670 | c.129C>A | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833976 | c.435C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834435 | c.894G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834438 | c.897C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853441 | c.-165C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853444 | c.-162C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853474 | c.-132C>G | upstream_gene_variant | 1.0 | linezolid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518268 | p.Thr52Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 1.0 | isoniazid | |
| kasA | 2518297 | c.183C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518312 | p.Asp66Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518315 | c.201G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518322 | p.Ser70Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518336 | c.222A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518417 | c.303G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518426 | c.312T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518429 | c.315A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518444 | c.330T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518447 | c.333T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518459 | c.345T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518462 | c.348A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518465 | c.351T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518468 | c.354A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518475 | c.361A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518486 | c.372G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518540 | c.426T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518570 | c.456_457insACC | conservative_inframe_insertion | 1.0 | isoniazid | |
| kasA | 2518573 | c.460_462delATC | conservative_inframe_deletion | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518636 | c.522C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518648 | c.534C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518651 | c.537C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518663 | c.549T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518688 | p.Val192Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518696 | c.582C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518699 | c.585C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518702 | c.588C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518715 | p.Pro201Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518771 | c.657C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518780 | p.Glu222Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518786 | c.672G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518787 | p.Arg225Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518798 | c.684G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518822 | c.708C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518840 | c.726C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518843 | c.729T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518849 | c.735G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518853 | p.Leu247Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726246 | c.54C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726261 | c.69G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726264 | c.72C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726285 | c.93C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726303 | c.111T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726312 | c.120T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726318 | p.Glu42Asp | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726319 | p.His43Tyr | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726322 | p.Pro44Glu | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726340 | p.Val50Ile | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726348 | c.156T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726357 | c.165A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726378 | c.186T>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726387 | c.195C>T | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726390 | c.198G>C | synonymous_variant | 1.0 | isoniazid | |
| Rv2477c | 2783029 | c.1014G>A | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783038 | p.Ala335Thr | missense_variant | 0.88 | kanamycin | Uncertain significance |
| levofloxacin | Uncertain significance | |||||
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783044 | c.999G>T | synonymous_variant | 0.93 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783047 | p.Asp332Glu | missense_variant | 0.93 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| amikacin | ||||||
| Rv2477c | 2783051 | p.Tyr331Phe | missense_variant | 0.93 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.94 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783080 | c.963G>C | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.88 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783098 | c.945C>G | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783101 | c.942G>C | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783105 | p.Val313Pro | missense_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783119 | c.924G>A | synonymous_variant | 0.88 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783149 | c.894G>C | synonymous_variant | 0.83 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 0.82 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783359 | c.684G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783386 | c.657G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | p.Pro206Gln | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783446 | c.597A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783611 | c.432C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783634 | p.Leu137Ile | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783635 | c.408C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783641 | c.402G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783645 | p.Asp133Gly | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783650 | c.393C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783659 | c.384A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783805 | p.Asn80Asp | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | c.222A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783872 | c.171G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783883 | c.160T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783884 | c.159T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783914 | c.129T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783917 | c.126C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783938 | c.105T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783950 | c.93C>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Leu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | ||||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783967 | c.76T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783986 | c.57G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783989 | c.54G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| pepQ | 2859723 | c.696T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | Not assoc w R - Interim | |||||
| pepQ | 2859735 | c.684G>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859738 | c.681C>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859747 | c.672C>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859750 | c.669C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859765 | c.654G>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859771 | c.648T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859778 | p.Val214Ala | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859780 | p.Gln213Ala | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859789 | c.630G>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859804 | c.615C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859807 | c.612C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859834 | c.585T>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| Rv2752c | 3064881 | c.1311T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | ||||||
| Rv2752c | 3064887 | c.1305A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064895 | p.Ala433Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| Rv2752c | 3064896 | c.1296T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064914 | c.1278T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3064923 | c.1269C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064932 | c.1260T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064935 | c.1257A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064941 | p.Gln417Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064950 | c.1242C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064956 | p.Ser412Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| Rv2752c | 3064959 | c.1233C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064995 | c.1197C>G | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| thyX | 3067304 | p.Glu214Ala | missense_variant | 0.93 | para-aminosalicylic_acid | |
| thyX | 3067316 | c.630A>G | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067391 | c.555G>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067406 | c.540A>G | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067409 | c.537C>T | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067427 | c.519G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067430 | c.516C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067442 | c.504C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067499 | c.447G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067515 | p.Ser144Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067530 | p.Ala139Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067541 | c.405C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067544 | p.Glu134Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067556 | p.His130Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067559 | p.Arg129Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067565 | p.Asp127Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067570 | p.Ala126Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067577 | c.369G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067583 | c.363C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067586 | c.360C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067595 | c.351C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067602 | p.Arg115Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067607 | p.Asp113Asn | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067613 | c.333G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067616 | c.330C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067619 | c.327A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067640 | c.306G>C | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067652 | c.294T>C | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067688 | c.258G>C | synonymous_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067721 | c.225T>C | synonymous_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067742 | c.204A>G | synonymous_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067763 | c.183C>G | synonymous_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067770 | p.Gly59Asp | missense_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067778 | c.168C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067790 | c.156C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 0.99 | para-aminosalicylic_acid | |
| thyX | 3067840 | p.Val36Leu | missense_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067847 | p.Pro33Gln | missense_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>T | synonymous_variant | 0.98 | para-aminosalicylic_acid | |
| thyX | 3067869 | p.Thr26Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067874 | c.72C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067886 | c.60A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067889 | c.57C>G | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067898 | p.Asp16Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067915 | c.31C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073999 | c.472_473delCGinsAGAA | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074002 | c.468_469delTG | frameshift_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074010 | c.462C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074022 | c.450C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074025 | p.Phe149Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074029 | p.Ala148Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074053 | p.Arg140Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074056 | p.Glu139Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074061 | p.Glu137Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074097 | c.375C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074100 | c.372T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074106 | c.366T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074121 | c.351T>C | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
| thyA | 3074262 | c.210T>C | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| thyA | 3074268 | c.204T>C | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| thyA | 3074274 | c.198T>C | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| thyA | 3074301 | c.171C>T | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074305 | p.Ala56Ile | missense_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074307 | c.165A>G | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074317 | p.Phe52Tyr | missense_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074319 | c.153T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074322 | c.150C>G | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074325 | c.147A>G | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074334 | c.138T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074339 | p.Leu45Ile | missense_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074349 | c.123T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074358 | c.112_114delTTGinsCTC | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074361 | c.111T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074364 | c.108T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074376 | p.Gln32His | missense_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074379 | c.93C>T | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074397 | c.75A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3624374 | p.Val179Leu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624386 | c.525C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624389 | c.522C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624407 | c.504C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624425 | p.Glu162Ala | missense_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624428 | c.483A>G | synonymous_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624434 | c.477G>A | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624448 | c.463C>T | synonymous_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624452 | c.459T>G | synonymous_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624455 | c.456G>A | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624464 | c.447A>G | synonymous_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624467 | c.444C>A | synonymous_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624470 | c.441T>C | synonymous_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624482 | c.429T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624485 | p.Asp142Gly | missense_variant | 0.95 | rifampicin | Not assoc w R |
| bedaquiline | Uncertain significance | |||||
| lpqB | 3624490 | p.Ser141Pro | missense_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624512 | c.399C>T | synonymous_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624515 | c.396G>C | synonymous_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624521 | c.390G>C | synonymous_variant | 0.94 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624527 | p.Gln128Val | missense_variant | 0.94 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624530 | c.381T>C | synonymous_variant | 0.94 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625095 | p.Glu507Lys | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625117 | c.-207T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625135 | c.1479A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625138 | c.-228C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625150 | c.-240C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625168 | c.-258G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625174 | c.-264C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625183 | c.-273G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625186 | c.-276T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625189 | c.1425A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625195 | c.-285A>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625198 | c.-288C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625204 | c.-294G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625246 | c.-336G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625258 | c.-348G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625273 | c.-363C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625276 | c.-366C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625279 | c.-369C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625285 | c.-375G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625528 | c.-618G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625540 | c.-630G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625558 | c.-648C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625592 | p.Ser341Asn | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625612 | c.-702G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625615 | c.-705G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625623 | p.Thr331Ala | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625627 | c.-717C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625636 | p.Ala326Glu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625657 | c.-747C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625687 | c.927G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625695 | c.-785C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626377 | p.Asp79Glu | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626383 | c.231G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626389 | c.223_225delAGGinsCGC | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626398 | p.Ile72Val | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626407 | c.207C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626410 | c.204T>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626413 | c.201T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626437 | c.177T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626443 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626451 | c.163C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626461 | c.153A>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626464 | c.150G>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626469 | p.Leu49Met | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626473 | c.141T>C | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626476 | c.138C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626482 | c.132G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626488 | c.126C>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626497 | c.117G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626506 | c.108A>T | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626705 | c.-92G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626708 | c.-95G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626786 | c.-173A>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626843 | c.-230G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626915 | c.-302C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626996 | c.-383G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627026 | c.324G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627071 | c.-458G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627131 | c.-518C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627170 | c.-557C>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627188 | c.-577_-575delTTAinsCTG | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627203 | c.-590C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627218 | c.-605G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627224 | c.-611G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627227 | c.-614T>G | upstream_gene_variant | 0.96 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627242 | c.108C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627269 | c.-656G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627272 | c.-659G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627301 | c.-688T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| fbiA | 3640681 | p.Val47Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | Uncertain significance | |||||
| clofazimine | Uncertain significance | |||||
| fbiA | 3640701 | p.Ile53Met | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiA | 3640708 | p.Leu56Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640713 | c.-822T>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiA | 3640714 | p.Val58Ile | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640722 | c.-813G>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640725 | c.-810T>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640743 | c.-792T>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640752 | c.-783C>T | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640761 | c.-774G>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640767 | c.-768C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640782 | c.-753C>T | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiA | 3640785 | p.Gln81His | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640788 | c.-747T>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640797 | c.-738T>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640803 | c.-732C>T | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiA | 3640808 | p.Met89Lys | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiA | 3640810 | p.Gln90Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640821 | c.-714G>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3640827 | c.-708T>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiA | 3640831 | p.Val97Met | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642602 | c.1068A>C | synonymous_variant | 0.85 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642614 | c.1080C>T | synonymous_variant | 0.88 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642620 | c.1086T>C | synonymous_variant | 0.89 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642623 | c.1089C>G | synonymous_variant | 0.91 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642633 | p.Asp367Gln | missense_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642656 | c.1122G>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642662 | c.1128C>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642665 | c.1131C>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642668 | c.1134A>C | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642674 | c.1140C>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642677 | c.1143A>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642680 | c.1146A>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642683 | c.1149C>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642684 | c.1150T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642692 | c.1158C>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642701 | c.1167C>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642704 | c.1170G>T | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642710 | c.1176G>C | synonymous_variant | 0.96 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642711 | p.Leu393Val | missense_variant | 0.96 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642731 | c.1197C>T | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642749 | c.1215T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| rpoA | 3877494 | p.Glu338Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877503 | p.Ala335Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877507 | p.Gly334Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877509 | p.Glu333Asp | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877513 | p.Thr332Asn | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877533 | c.975C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877548 | c.960C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877554 | c.954G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877567 | p.Ser314His | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877569 | p.Pro313Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877599 | c.909G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877674 | c.834C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877679 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877689 | c.819C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877731 | c.777G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877806 | c.702C>T | synonymous_variant | 0.99 | rifampicin | |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3877872 | c.636C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877893 | c.615C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 0.98 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | c.600T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877962 | c.546G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878043 | c.465G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878046 | c.462T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878050 | p.Arg153Lys | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878100 | c.408C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878184 | c.324C>A | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878229 | c.279C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoA | 3878232 | c.276G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878358 | c.150C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878361 | c.147G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878400 | c.108T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878409 | c.99C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878451 | c.57C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878454 | c.54A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878460 | p.Asp16Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878464 | p.Thr15Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878468 | p.Leu14Ile | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878470 | p.Val13Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878475 | c.33G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878490 | c.18C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878823 | c.-316G>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878843 | c.-337_-336delCGinsAA | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878845 | c.-340_-338delGTGinsATC | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.96 | rifampicin | Uncertain significance |
| rpoA | 3878881 | c.-374C>G | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878886 | c.-379G>A | upstream_gene_variant | 0.95 | rifampicin | Uncertain significance |
| rpoA | 3878890 | c.-383C>G | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878894 | c.-388_-387delCAinsAG | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878896 | c.-389G>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878908 | c.-403_-401delAACinsCTG | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.95 | rifampicin | Uncertain significance |
| rpoA | 3878917 | c.-410G>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878935 | c.-428C>T | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoA | 3878947 | c.-440G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878953 | c.-446C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878956 | c.-449G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878971 | c.-464C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878980 | c.-473C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879034 | c.-528_-527delAGinsGT | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879037 | c.-530G>C | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879040 | c.-533G>C | upstream_gene_variant | 0.9 | rifampicin | |
| rpoA | 3879043 | c.-536C>G | upstream_gene_variant | 0.91 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879097 | c.-590C>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.96 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879178 | c.-671T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879190 | c.-683C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879193 | c.-686G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879196 | c.-689C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879199 | c.-692C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879202 | c.-695T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879208 | c.-701C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879226 | c.-719G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879232 | c.-725A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879238 | c.-731C>T | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clpC1 | 4038278 | c.2427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038293 | c.2412G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038308 | c.2397G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038320 | c.2385G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038347 | c.2358G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038353 | p.Gln784Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038407 | c.2298G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038436 | p.Ala757Ser | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.94 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038452 | c.2253G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038485 | p.Gly740Lys | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038488 | p.Ala739Glu | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038494 | c.2211G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038509 | p.Asp732Glu | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038536 | c.2169C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038647 | c.2058T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038677 | p.Pro676Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038694 | p.Ser671Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038698 | c.2007C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038764 | c.1941C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038776 | c.1929G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038838 | c.1867C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038845 | c.1858_1860delTCGinsAGT | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039001 | p.Asn568Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039009 | c.1696C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039016 | c.1689C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039031 | c.1674T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039034 | c.1671C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039090 | c.1615C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039091 | c.1614G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039118 | c.1587C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039133 | c.1572C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>T | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039163 | p.Leu514Ile | missense_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039283 | c.1422C>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039292 | c.1413C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039325 | c.1380G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039334 | c.1371G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039338 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039346 | c.1359G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039358 | c.1345_1347delAGCinsTCG | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039361 | c.1344C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039394 | c.1311G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039406 | c.1299G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040552 | c.153G>A | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040555 | c.150G>A | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>C | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>T | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040600 | c.105A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040615 | c.90C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| glpK | 4138451 | c.1305T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138454 | c.1302G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138457 | c.1299C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138464 | p.Gly431Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138466 | c.1290C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138472 | c.1284G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138478 | c.1278T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138481 | c.1275G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138484 | c.1272G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138490 | c.1266G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138495 | p.Gln421Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138496 | c.1260G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138502 | c.1254T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138511 | c.1245C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138514 | c.1242A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138517 | p.Glu413Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138529 | c.1227G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138535 | c.1221T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138556 | c.1200G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138565 | c.1191G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138580 | c.1176C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138596 | p.Phe387Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138598 | c.1158G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138601 | c.1155G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138610 | c.1146C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138616 | c.1140G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138625 | c.1131G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138634 | c.1122G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138654 | c.1102C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138670 | c.1086G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138681 | p.Met359Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138682 | c.1074C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138695 | p.Pro354Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138703 | c.1053C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138751 | c.1005T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138781 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138796 | c.960A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138802 | c.954G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138808 | c.948G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| embC | 4240642 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240651 | c.789G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240654 | c.792C>G | synonymous_variant | 0.86 | ethambutol | Not assoc w R - Interim |
| embC | 4240655 | p.Ala265Pro | missense_variant | 1.0 | ethambutol | |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240673 | p.Gly271Ser | missense_variant | 1.0 | ethambutol | |
| embC | 4240678 | c.816T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240681 | c.819G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240685 | p.Thr275Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240693 | c.831T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240695 | p.Ile278Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4240699 | c.837C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240736 | p.Ser292Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240786 | c.924C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240795 | c.933C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240807 | c.945C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240822 | c.960C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240837 | c.975C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240852 | c.990G>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240867 | c.1005T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240870 | c.1008T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240875 | p.Ser338Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4240879 | c.1017G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240885 | c.1023T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240897 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240900 | c.1038A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240907 | c.1045C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241039 | p.Asp393Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4241047 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241056 | c.1194C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241072 | c.1210C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241086 | c.1224G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241141 | p.Ile427Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241185 | c.1323G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241188 | c.1326C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241194 | c.1332C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241203 | c.1341T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241215 | c.1353C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241230 | c.1368A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241233 | c.1371G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241236 | c.1374C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241248 | c.1386G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241251 | c.1389T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241252 | p.Ser464Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4241256 | p.Arg465Lys | missense_variant | 1.0 | ethambutol | |
| embC | 4241260 | c.1398G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241272 | c.1410A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241275 | c.1413A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241281 | c.1419G>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241284 | c.1422G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241301 | p.Ala480Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241304 | p.Thr481Ser | missense_variant | 1.0 | ethambutol | |
| embC | 4241313 | p.Ala484Val | missense_variant | 1.0 | ethambutol | |
| embC | 4241319 | p.Pro486Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241326 | c.1464T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241329 | c.1467T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241332 | c.1470T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241338 | c.1476C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241494 | c.1632C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241500 | c.1638A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241518 | c.1656A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241521 | c.1659T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241527 | c.1665C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241530 | c.1668C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241536 | c.1674A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241539 | c.1677T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241545 | c.1683T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241548 | c.1686T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241551 | c.1689A>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241554 | c.1692G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241560 | c.1698C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241584 | c.1722T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241587 | c.1725C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241591 | p.Leu577Ile | missense_variant | 1.0 | ethambutol | |
| embC | 4241608 | c.1746C>T | synonymous_variant | 0.97 | ethambutol | |
| embC | 4241611 | c.1749G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241614 | c.1752A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241626 | c.1764T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241629 | c.1767C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241644 | c.1782G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241648 | c.1786T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241656 | c.1794G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241665 | c.1803G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241671 | c.1809T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241677 | c.1815G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241691 | p.Gly610Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241695 | c.1833T>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241707 | c.1845G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241713 | c.1851G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241719 | c.1857G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241723 | p.Val621Met | missense_variant | 1.0 | ethambutol | |
| embC | 4241734 | c.1872C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241735 | p.Val625Leu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241741 | p.Val627Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241750 | p.Leu630Val | missense_variant | 1.0 | ethambutol | |
| embC | 4241755 | c.1893C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241770 | c.1908T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241791 | c.1929G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241794 | c.1932C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241797 | c.1935C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241809 | c.1947A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 0.93 | ethambutol | |
| embA | 4242832 | c.-401A>G | upstream_gene_variant | 0.94 | ethambutol | |
| embC | 4242835 | c.2973C>T | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| embA | 4242844 | c.-389A>G | upstream_gene_variant | 0.94 | ethambutol | |
| embA | 4242847 | c.-386C>A | upstream_gene_variant | 0.94 | ethambutol | |
| embA | 4242856 | c.-377C>T | upstream_gene_variant | 0.94 | ethambutol | |
| embA | 4242859 | c.-374C>T | upstream_gene_variant | 0.93 | ethambutol | |
| embC | 4242863 | p.Tyr1001Asn | missense_variant | 0.92 | ethambutol | |
| embC | 4242872 | p.Asp1004Ile | missense_variant | 0.9 | ethambutol | |
| embC | 4242878 | p.Thr1006Ala | missense_variant | 0.9 | ethambutol | |
| embC | 4242883 | c.3021C>G | synonymous_variant | 0.9 | ethambutol | Not assoc w R - Interim |
| embB | 4245737 | c.-777A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245740 | c.-774T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245743 | c.-771C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245764 | c.-750G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245772 | p.Asn847Ser | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245785 | c.2553G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245797 | c.-717C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245807 | c.-707_-705delTTAinsCTT | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245815 | c.-699C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245820 | p.Ser863Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4245836 | c.-678G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245839 | c.-675G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245842 | c.-672G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245845 | c.-669T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245851 | c.-663G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245860 | c.-654C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246055 | c.2823T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246064 | c.-450T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246070 | c.-444G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246080 | p.Pro950Ser | missense_variant | 1.0 | ethambutol | |
| embA | 4246088 | c.2856A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embB | 4246097 | c.-417C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246125 | p.Glu965Gln | missense_variant | 1.0 | ethambutol | |
| embA | 4246128 | p.Ser966Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4246138 | p.Arg969Gln | missense_variant | 1.0 | ethambutol | |
| embB | 4246140 | c.-374T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246151 | c.2919A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4246152 | p.Ala974Gln | missense_variant | 1.0 | ethambutol | |
| embA | 4246155 | p.Thr975Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4246164 | c.2932T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246178 | c.-336G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246184 | c.-330A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246187 | c.-327C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246205 | c.-309A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4247370 | p.Gly286Val | missense_variant | 1.0 | ethambutol | |
| embB | 4247389 | c.876C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247395 | c.882C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247401 | c.888T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247404 | c.891G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247437 | c.924A>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247440 | c.927C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247527 | c.1014G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247876 | c.1363C>T | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247887 | c.1374C>T | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
| embB | 4247890 | c.1377C>T | synonymous_variant | 0.88 | ethambutol | |
| embB | 4247899 | p.Met462Ile | missense_variant | 0.89 | ethambutol | |
| embB | 4247909 | c.1396T>C | synonymous_variant | 0.89 | ethambutol | |
| embB | 4247917 | c.1404C>A | synonymous_variant | 0.89 | ethambutol | |
| embB | 4247920 | c.1407T>G | synonymous_variant | 0.9 | ethambutol | |
| embB | 4247926 | c.1413C>T | synonymous_variant | 0.92 | ethambutol | |
| embB | 4247938 | c.1425G>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247940 | p.Leu476Trp | missense_variant | 0.93 | ethambutol | |
| embB | 4247951 | p.Ser480Ala | missense_variant | 0.94 | ethambutol | |
| embB | 4247957 | p.Met482Leu | missense_variant | 0.95 | ethambutol | |
| embB | 4247965 | c.1452C>A | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247972 | p.Thr487Phe | missense_variant | 0.95 | ethambutol | |
| embB | 4247977 | c.1464C>G | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247984 | p.Thr491Pro | missense_variant | 0.95 | ethambutol | |
| embB | 4248007 | c.1494C>G | synonymous_variant | 0.98 | ethambutol | |
| embB | 4248008 | c.1495C>T | synonymous_variant | 0.98 | ethambutol | |
| embB | 4248022 | p.Leu503Phe | missense_variant | 0.97 | ethambutol | |
| embB | 4248025 | c.1512A>G | synonymous_variant | 0.97 | ethambutol | |
| embB | 4248035 | p.Val508Ile | missense_variant | 0.97 | ethambutol | |
| embB | 4248042 | p.Ala510Gly | missense_variant | 1.0 | ethambutol | |
| embB | 4248044 | p.Lys511Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248055 | c.1542G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248064 | c.1551G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248109 | c.1596C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248118 | c.1605T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248241 | c.1728C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248319 | c.1806A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248322 | c.1809G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248334 | c.1821C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248337 | c.1824G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248350 | c.1837T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248355 | c.1842A>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248358 | c.1845C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248361 | c.1848A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248362 | p.Ser617Lys | missense_variant | 1.0 | ethambutol | |
| embB | 4248379 | c.1866G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249342 | c.2829C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249345 | c.2832C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249366 | p.Glu951Asp | missense_variant | 1.0 | ethambutol | |
| embB | 4249381 | c.2868A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249417 | c.2904A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249423 | p.Asp970Glu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4249424 | c.2911C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249432 | c.2919A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249441 | c.2928A>G | synonymous_variant | 0.97 | ethambutol | Not assoc w R - Interim |
| embB | 4249444 | c.2931T>C | synonymous_variant | 0.97 | ethambutol | |
| embB | 4249447 | c.2934G>C | synonymous_variant | 0.97 | ethambutol | |
| embB | 4249450 | c.2937C>G | synonymous_variant | 0.97 | ethambutol | |
| embB | 4249454 | p.Thr981Ser | missense_variant | 0.97 | ethambutol | |
| embB | 4249469 | p.Leu986Met | missense_variant | 0.98 | ethambutol | |
| embB | 4249486 | c.2973T>G | synonymous_variant | 0.97 | ethambutol | |
| embB | 4249487 | c.2974T>C | synonymous_variant | 0.97 | ethambutol | |
| embB | 4249525 | c.3012T>C | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| embB | 4249528 | c.3015C>T | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| embB | 4249529 | p.Ile1006Val | missense_variant | 0.94 | ethambutol | |
| embB | 4249532 | p.Ala1007Thr | missense_variant | 0.91 | ethambutol | Uncertain significance |
| embB | 4249537 | p.Glu1008Asp | missense_variant | 0.94 | ethambutol | |
| embB | 4249552 | c.3039C>G | synonymous_variant | 0.94 | ethambutol | |
| embB | 4249558 | c.3045A>C | synonymous_variant | 0.94 | ethambutol | |
| embB | 4249568 | p.Ser1019Thr | missense_variant | 0.93 | ethambutol | |
| embB | 4249573 | c.3060T>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4249581 | p.Leu1023Gln | missense_variant | 0.96 | ethambutol | |
| embB | 4249594 | c.3081G>C | synonymous_variant | 0.97 | ethambutol | |
| embB | 4249607 | p.Thr1032Val | missense_variant | 0.95 | ethambutol | |
| embB | 4249624 | c.3111C>T | synonymous_variant | 0.94 | ethambutol | |
| embB | 4249627 | c.3114G>C | synonymous_variant | 0.94 | ethambutol | |
| embB | 4249637 | p.Leu1042Val | missense_variant | 0.93 | ethambutol |
