TB-Profiler result

Run: SRR7535082
Summary

Run ID: SRR7535082

Sample name:

Date: 2024-10-03T16:41:31.613381

Number of reads: 234358

Percentage reads mapped: 1.6

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.99
lineage4.9 Euro-American (H37Rv-like) None 0.94
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.91 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.91 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.83 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.83 isoniazid
dnaA 769 p.Ala257Ser missense_variant 1.0 isoniazid Uncertain significance
dnaA 1260 c.1260C>T synonymous_variant 1.0 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 1.0 isoniazid
dnaA 1275 p.Asp425Glu missense_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1281 c.1281C>G synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1314 c.1314A>T synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 0.91 isoniazid
dnaA 1332 c.1332A>T synonymous_variant 0.91 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 0.91 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 0.91 isoniazid
gyrB 6109 c.870G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.67 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrB 6175 c.936G>A synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 6589 c.-713G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 6601 c.-701A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7763 c.462T>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
fgd1 491037 c.255C>G synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491055 c.273C>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491064 c.282A>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fgd1 491067 c.285C>T synonymous_variant 0.83 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fgd1 491073 c.291C>T synonymous_variant 0.91 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491077 p.Asn99Asp missense_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491094 c.312C>T synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 1.0 pretomanid
delamanid
clofazimine
ccsA 620619 c.729G>C synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620652 c.762C>G synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 0.84 kanamycin
capreomycin
amikacin
ccsA 620670 c.780C>T synonymous_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.82 kanamycin
capreomycin
amikacin
Rv0565c 657636 c.-167_-166delAGinsTC upstream_gene_variant 0.93 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.93 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.89 ethionamide
Rv0565c 657670 c.-200A>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.94 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.94 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.88 ethionamide
Rv0565c 657703 c.-233C>A upstream_gene_variant 0.87 ethionamide
hadA 731753 c.-177A>G upstream_gene_variant 0.92 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.83 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.92 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.91 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.91 isoniazid
nusG 734499 c.246G>C synonymous_variant 0.94 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.92 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 1.0 rifampicin
rpoB 760139 c.333A>T synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.97 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.96 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.96 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.96 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760433 c.627C>T synonymous_variant 1.0 rifampicin
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760591 p.Val262Ala missense_variant 0.9 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.9 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.94 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760703 c.897C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.9 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 0.92 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.96 rifampicin
rpoB 761288 c.1482G>T synonymous_variant 0.96 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 1.0 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>C synonymous_variant 1.0 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.94 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.8 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.73 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.75 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.73 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.7 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.94 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.93 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.93 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.93 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762224 c.2418C>G synonymous_variant 0.92 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.96 rifampicin
rpoB 762287 c.2481C>T synonymous_variant 0.96 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 0.91 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.9 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762341 c.2535G>C synonymous_variant 0.87 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.92 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.93 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.93 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.93 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.93 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.94 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.88 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.89 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.78 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.78 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762894 c.3088C>T synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 762911 p.Ile1035Met missense_variant 0.58 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 762932 c.-438G>T upstream_gene_variant 0.56 rifampicin
rpoB 762939 p.Met1045Leu missense_variant 0.58 rifampicin
rpoB 762942 p.Ile1046Val missense_variant 0.62 rifampicin Uncertain significance
rpoC 762947 c.-423C>G upstream_gene_variant 0.62 rifampicin
rpoB 762959 c.3153G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762989 c.3183G>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 762998 c.-372G>A upstream_gene_variant 0.33 rifampicin
rpoB 763004 c.3198G>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763022 c.-348C>G upstream_gene_variant 0.94 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.94 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.88 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.89 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.94 rifampicin
rpoC 763169 c.-201A>G upstream_gene_variant 0.94 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 0.85 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.88 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.88 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.88 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 0.82 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.83 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.89 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>T synonymous_variant 0.86 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.94 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.94 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.97 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.96 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.96 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.92 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.92 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.95 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.93 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.85 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.83 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.82 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.82 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.82 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.83 rifampicin
rpoC 763882 c.513G>A synonymous_variant 0.83 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.86 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.86 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.87 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.87 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.93 rifampicin
rpoC 763933 c.564C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.92 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.92 rifampicin
rpoC 763947 p.Ala193Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.93 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.93 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764353 c.984G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.95 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.96 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.97 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.96 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.88 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764851 c.1482C>T synonymous_variant 0.83 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.95 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.95 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.3 rifampicin
rpoC 764905 c.1536C>T synonymous_variant 0.46 rifampicin
rpoC 764911 c.1542A>C synonymous_variant 0.51 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.49 rifampicin
rpoC 764912 p.Met515His missense_variant 0.46 rifampicin
rpoC 764918 p.Val517Ile missense_variant 0.53 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.41 rifampicin
rpoC 764939 c.1570C>T synonymous_variant 0.57 rifampicin
rpoC 764947 c.1578G>C synonymous_variant 0.55 rifampicin
rpoC 764948 c.1579_1581delTTGinsCTC synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764953 c.1584G>T synonymous_variant 0.55 rifampicin
rpoC 764956 c.1587T>C synonymous_variant 0.57 rifampicin
rpoC 764958 p.Glu530Ala missense_variant 0.57 rifampicin
rpoC 764962 c.1593G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765817 c.2448G>C synonymous_variant 0.8 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.9 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.9 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.91 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.91 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.94 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.92 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.8 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.8 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.73 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.73 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 0.88 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
mmpL5 775915 p.Ala856Ser missense_variant 0.7 bedaquiline
clofazimine
mmpL5 775951 c.2530C>T synonymous_variant 0.71 bedaquiline
clofazimine
mmpL5 775955 p.Ile842Val missense_variant 0.37 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.94 bedaquiline
clofazimine
mmpL5 776681 p.Leu600Ile missense_variant 0.73 bedaquiline
clofazimine
mmpL5 776693 p.Val596Met missense_variant 0.73 bedaquiline
clofazimine
mmpL5 776704 p.Asp593Asn missense_variant 0.67 bedaquiline
clofazimine
mmpL5 776715 p.Lys589Pro missense_variant 0.83 bedaquiline
clofazimine
rpsL 781572 p.Gln5Asn missense_variant 0.83 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.86 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.86 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.86 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.86 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.88 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.9 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.91 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.9 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.89 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.95 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.95 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.95 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.95 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.96 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.96 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.96 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.97 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.97 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.96 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.96 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.96 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.96 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781901 c.342C>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800543 c.-266C>T upstream_gene_variant 0.92 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.92 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.8 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.8 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.83 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.82 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.8 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.8 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.82 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.82 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.83 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.79 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.8 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.8 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.83 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.89 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.89 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.9 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.88 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.88 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.88 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.91 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.9 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.95 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.93 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.85 linezolid
fbiC 1303531 p.Met201Leu missense_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1303536 c.606G>A synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303539 c.609G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303551 c.621G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303554 c.624G>A synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1303581 c.651G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303587 c.657G>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1303593 c.663G>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304567 p.Phe546Tyr missense_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364709 c.297T>C synonymous_variant 0.85 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.86 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.77 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.79 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.82 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.94 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.94 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 0.93 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 0.93 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.93 pyrazinamide
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 1.0 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 1.0 bedaquiline
atpE 1461227 c.183G>A synonymous_variant 0.9 bedaquiline
rrs 1471923 n.78_80delTCTinsCC non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.92 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.84 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.97 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.92 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.25 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 0.85 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.86 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.89 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.9 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472252 n.407G>A non_coding_transcript_exon_variant 0.89 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.89 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.71 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.72 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.77 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.77 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472785 n.940G>T non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472786 n.941C>G non_coding_transcript_exon_variant 0.75 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.74 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472814 n.969G>A non_coding_transcript_exon_variant 0.72 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472824 n.979T>C non_coding_transcript_exon_variant 0.25 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.91 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.94 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473139 n.1294T>C non_coding_transcript_exon_variant 0.34 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473147 n.1302G>C non_coding_transcript_exon_variant 0.43 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1473198 n.1354delC non_coding_transcript_exon_variant 0.67 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473204 n.1359C>T non_coding_transcript_exon_variant 0.66 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.97 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAGT non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476411 n.2754G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476463 n.2806C>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.76 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476483 n.2826G>A non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.46 capreomycin
linezolid Uncertain significance
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.45 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rpsA 1833554 p.Thr5Ser missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.94 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.94 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.93 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.94 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.94 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.95 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.95 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.88 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.94 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.95 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.96 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.93 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.88 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.9 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.88 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.92 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.93 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.92 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.88 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.88 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.92 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.89 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.88 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.88 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.93 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.9 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.92 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.88 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.92 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.94 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.94 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
kasA 2517941 c.-174C>G upstream_gene_variant 0.95 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.95 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.94 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.95 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.94 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 0.93 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 0.83 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.92 isoniazid
Rv2477c 2782453 c.1590C>T synonymous_variant 0.9 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.92 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2752c 3065058 c.1134C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065061 c.1131C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065064 c.1128G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065082 c.1110G>T synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
thyX 3067340 c.606G>A synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067346 c.600C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.82 para-aminosalicylic_acid
thyX 3067376 c.570G>C synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067415 c.531C>T synonymous_variant 0.82 para-aminosalicylic_acid
rpoA 3877530 c.978C>A synonymous_variant 0.73 rifampicin
rpoA 3877534 p.Val325Ala missense_variant 0.73 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 0.73 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 0.73 rifampicin
rpoA 3877569 p.Pro313Ala missense_variant 0.73 rifampicin
rpoA 3877584 c.924C>G synonymous_variant 0.85 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.85 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877602 c.906C>T synonymous_variant 0.93 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.82 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.86 rifampicin
rpoA 3877875 c.633T>A synonymous_variant 0.92 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.93 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.94 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 1.0 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878238 c.270C>T synonymous_variant 1.0 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 1.0 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
clpC1 4038551 c.2154C>G synonymous_variant 0.86 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.81 pyrazinamide
clpC1 4038584 c.2121G>T synonymous_variant 0.79 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.69 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.72 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.67 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.65 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.64 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.62 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.62 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.62 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.62 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.71 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.69 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 0.71 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.71 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.75 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.78 pyrazinamide
clpC1 4038782 c.1923G>A synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4038790 c.1915C>T synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.89 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.91 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.95 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038997 c.1708T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039025 c.1680C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039158 p.Lys516Arg missense_variant 1.0 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039265 c.1440C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040306 c.399G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
glpK 4139594 c.162C>A synonymous_variant 0.91 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139602 c.154C>A synonymous_variant 0.91 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139608 c.148C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139637 p.Ala40Gly missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139647 p.Ala37Thr missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139648 c.108T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139652 p.His35Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139672 c.84C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4240768 c.906G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240777 c.915G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240786 c.924C>T synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.93 ethambutol
embC 4240828 c.966G>A synonymous_variant 0.93 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.92 ethambutol
embB 4247455 c.942C>T synonymous_variant 1.0 ethambutol
embB 4247464 c.951C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 1.0 ethambutol
embB 4247527 c.1014G>C synonymous_variant 1.0 ethambutol
embB 4247536 c.1023C>A synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.8 ethambutol Uncertain significance
embB 4248233 c.1720C>T synonymous_variant 0.93 ethambutol
embB 4248242 p.Val577Ile missense_variant 0.93 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.93 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.92 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.92 ethambutol