TB-Profiler result

Run: SRR1183111

Summary

Run ID: SRR1183111

Sample name:

Date: 2024-04-14T15:00:11.977234

Number of reads: 584817

Percentage reads mapped: 14.74

Median coverage: 3.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3.1.2.2 East-African-Indian RD750 0.07
lineage4.9 Euro-American (H37Rv-like) None 0.86
La1.7.1 M.bovis None 0.19
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.493_495delATTinsCC Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.532_534delGCAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303462 c.532_534delGCAinsTG frameshift_variant&stop_gained 0.67 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.71 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155107 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
katG 2155617 c.493_495delATTinsCC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 1.0 isoniazid
dnaA 24 c.24C>T synonymous_variant 1.0 isoniazid
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 33 c.33A>C synonymous_variant 1.0 isoniazid
dnaA 60 c.60T>C synonymous_variant 1.0 isoniazid
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 714 c.714C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>A synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCT frameshift_variant&synonymous_variant 1.0 isoniazid Uncertain significance
dnaA 819 c.819C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.97 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.97 isoniazid
dnaA 891 c.891C>T synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 897 c.897A>G synonymous_variant 0.91 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>G synonymous_variant 0.89 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.88 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.88 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 936 c.936C>G synonymous_variant 0.86 isoniazid
dnaA 939 c.939C>G synonymous_variant 0.86 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.85 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.85 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.91 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.94 isoniazid
dnaA 996 c.996A>G synonymous_variant 1.0 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 1.0 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 1.0 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 1.0 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 1.0 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.97 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.97 isoniazid
dnaA 1078 c.1078_1080delCTCinsTG frameshift_variant&missense_variant 0.96 isoniazid Uncertain significance
dnaA 1092 c.1092T>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 1095 c.1095C>T synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.94 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 0.93 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 1.0 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 1.0 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.96 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.95 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.94 isoniazid
dnaA 1311 c.1311C>T synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 1317 c.1317A>G synonymous_variant 0.86 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.9 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.95 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1437 c.1437G>A synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1446 c.1446C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1461 c.1461C>A synonymous_variant 1.0 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1497 c.1497T>G synonymous_variant 1.0 isoniazid
dnaA 1500 c.1500C>G synonymous_variant 1.0 isoniazid
dnaA 1506 c.1506T>A synonymous_variant 1.0 isoniazid
gyrB 5314 c.75C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5326 c.87T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5329 c.90C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5338 c.99C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5344 c.105C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5359 c.120C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 5362 c.123T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6106 c.867C>A synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6122 p.Ala295Asn missense_variant 0.57 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6316 c.-986G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6346 c.-956C>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>T upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.92 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6892 c.-410C>T upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6902 c.1663_1665delCTCinsTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6997 c.-305G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7076 c.1837_1839delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 7081 c.-221T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7174 c.-128C>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7362 c.61_63delGAGinsCA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7643 c.342C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7646 c.345C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 7820 c.519G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8253 p.Ile318Leu missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8765 p.Asp488Glu missense_variant 0.81 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8789 c.1488C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8798 c.1497C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8810 c.1509A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8818 p.Ser506Asn missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8840 c.1539C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8888 c.1587C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8933 c.1632G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8936 c.1635G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9326 c.2025G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9435 c.2134C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
Rv0010c 13884 c.-326A>G upstream_gene_variant 0.91 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 0.91 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 0.91 isoniazid
Rv0010c 13894 c.-336C>T upstream_gene_variant 0.92 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.89 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.89 isoniazid
fgd1 490899 c.117C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490983 c.201G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490988 p.Leu69Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491040 c.258C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491175 c.393G>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491178 c.396G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491320 p.Ala180Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491592 c.810G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491631 c.849C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
mshA 574667 c.-681G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 575087 c.-261C>G upstream_gene_variant 0.9 ethionamide
isoniazid
ccsA 620238 c.348G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620263 p.Gly125Ser missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620685 c.795G>A synonymous_variant 0.96 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620781 c.891C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620829 c.939G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656304 c.1167T>C synonymous_variant 1.0 ethionamide
Rv0565c 656307 c.1164G>C synonymous_variant 1.0 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 1.0 ethionamide
Rv0565c 656322 c.1149C>T synonymous_variant 1.0 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 1.0 ethionamide
Rv0565c 656334 c.1137A>G synonymous_variant 1.0 ethionamide
Rv0565c 657183 c.288G>A synonymous_variant 0.94 ethionamide
Rv0565c 657189 c.282C>A synonymous_variant 0.95 ethionamide
Rv0565c 657193 p.Met93Thr missense_variant 0.95 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.95 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 0.96 ethionamide Uncertain significance
Rv0565c 657210 c.261C>T synonymous_variant 0.96 ethionamide Not assoc w R - Interim
Rv0565c 657213 c.258C>T synonymous_variant 0.96 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.97 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.96 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.96 ethionamide Uncertain significance
Rv0565c 657252 c.219G>C synonymous_variant 0.98 ethionamide
Rv0565c 657255 c.216G>A synonymous_variant 0.98 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.98 ethionamide
Rv0565c 657294 c.177C>A synonymous_variant 1.0 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 1.0 ethionamide
Rv0565c 657312 c.159C>T synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 1.0 ethionamide
Rv0565c 657626 c.-156C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657668 c.-198C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657695 c.-225C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657704 c.-234G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657725 c.-255G>A upstream_gene_variant 1.0 ethionamide
hadA 731686 c.-244_-243insATGT upstream_gene_variant 1.0 isoniazid
hadA 731689 c.-240_-237delAGAC upstream_gene_variant 1.0 isoniazid
hadA 731695 c.-235C>T upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 1.0 isoniazid
hadA 731708 c.-222G>A upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731726 c.-204C>G upstream_gene_variant 0.98 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.98 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.97 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 0.97 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.97 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.98 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.98 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.98 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 1.0 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732305 c.376_378delATCinsGG frameshift_variant&missense_variant 0.79 isoniazid Uncertain significance
hadA 732308 p.Val127Ile missense_variant 0.79 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.79 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.79 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.79 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.86 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.9 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.97 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734454 c.201A>G synonymous_variant 0.92 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.94 rifampicin
nusG 734520 c.267C>G synonymous_variant 0.95 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>T synonymous_variant 1.0 rifampicin
nusG 734595 c.342C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.95 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.9 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>T synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734931 c.678A>T synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734943 c.690G>C synonymous_variant 1.0 rifampicin
nusG 734950 p.Gly233Thr missense_variant 1.0 rifampicin
rpoB 760043 c.237C>T synonymous_variant 1.0 rifampicin
rpoB 760046 c.240G>C synonymous_variant 1.0 rifampicin
rpoB 760056 c.250_252delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760109 c.303C>T synonymous_variant 0.97 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.98 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.95 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.96 rifampicin
rpoB 760181 c.375T>A synonymous_variant 0.96 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760295 c.489C>T synonymous_variant 1.0 rifampicin
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.98 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.98 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.94 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760358 c.552C>G synonymous_variant 0.98 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.97 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.97 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>T synonymous_variant 0.96 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 1.0 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>G synonymous_variant 1.0 rifampicin
rpoB 760520 c.714C>G synonymous_variant 0.97 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.97 rifampicin Uncertain significance
rpoB 760526 c.720G>A synonymous_variant 0.97 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.96 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.95 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.96 rifampicin
rpoB 760601 c.795C>T synonymous_variant 0.96 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760622 c.816C>T synonymous_variant 1.0 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760667 c.861G>A synonymous_variant 0.98 rifampicin
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.98 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.98 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.98 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.98 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.97 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.98 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.98 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.98 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760892 c.1086C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.98 rifampicin
rpoB 760937 c.1131G>A synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 1.0 rifampicin
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.95 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.94 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.95 rifampicin
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 1.0 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761432 c.1626C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761452 p.Val549Glu missense_variant 1.0 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 1.0 rifampicin
rpoB 761465 c.1659G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761471 c.1665C>T synonymous_variant 1.0 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>A synonymous_variant 1.0 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.93 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.93 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 0.93 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.93 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 0.91 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.91 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.92 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.97 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.97 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.97 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.97 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.97 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.96 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.96 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.97 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.98 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.98 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>T synonymous_variant 0.98 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.98 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.98 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.98 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 0.98 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.95 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.95 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.95 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.96 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.97 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.97 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.94 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.94 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.95 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762431 c.2625C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.96 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.96 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762563 c.-807G>A upstream_gene_variant 0.96 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.92 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.92 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762902 c.-468C>T upstream_gene_variant 0.97 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 0.97 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 763034 c.-336C>A upstream_gene_variant 1.0 rifampicin
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.96 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.96 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.95 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.94 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.94 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.96 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763241 c.-129G>A upstream_gene_variant 0.97 rifampicin
rpoC 763250 c.-120C>T upstream_gene_variant 0.96 rifampicin
rpoC 763253 c.-117G>T upstream_gene_variant 0.96 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.92 rifampicin
rpoC 763265 c.-105G>A upstream_gene_variant 0.9 rifampicin
rpoC 763402 c.33C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 0.99 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.98 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763726 c.357C>T synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763771 c.402C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 1.0 rifampicin
rpoC 763963 c.594C>G synonymous_variant 1.0 rifampicin
rpoC 763967 p.Gly200Ser missense_variant 1.0 rifampicin
rpoC 763972 c.603C>T synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764159 c.790C>T synonymous_variant 0.98 rifampicin
rpoC 764167 c.798G>A synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764218 c.849C>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>A synonymous_variant 1.0 rifampicin
rpoC 764246 c.877_879delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.98 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 1.0 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 1.0 rifampicin
rpoC 764605 c.1236G>A synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 1.0 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 1.0 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765065 c.1696C>T synonymous_variant 1.0 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765208 c.1839T>C synonymous_variant 1.0 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 1.0 rifampicin
rpoC 765233 c.1864_1866delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765247 c.1878C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765248 c.1879T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765251 c.1882_1884delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765283 c.1914C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765316 c.1947G>A synonymous_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765406 c.2037G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.99 rifampicin
rpoC 765625 c.2256C>T synonymous_variant 0.99 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 1.0 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.98 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.98 rifampicin
rpoC 765811 c.2442T>A synonymous_variant 0.98 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.99 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.99 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.99 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.99 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766061 p.Val898Ile missense_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766093 c.2724C>A synonymous_variant 1.0 rifampicin
rpoC 766095 p.Thr909Ser missense_variant 1.0 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 1.0 rifampicin
rpoC 766123 c.2754C>A synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766288 c.2919C>G synonymous_variant 1.0 rifampicin
rpoC 766309 c.2940G>A synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.95 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.94 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.97 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.98 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 0.98 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.98 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.98 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.98 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766930 c.3561G>A synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>G synonymous_variant 1.0 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>G synonymous_variant 0.96 rifampicin
rpoC 767264 p.Ala1299Gln missense_variant 0.92 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.91 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.89 rifampicin
mmpL5 775851 p.Ser877Thr missense_variant 0.94 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775874 c.2607C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775889 c.2592C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775910 c.2571G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.9 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.9 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776030 c.2451G>T synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776036 c.2445G>T synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776039 c.2442C>G synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 776051 c.2428_2430delTTGinsCC frameshift_variant&missense_variant 0.64 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776056 p.Val809Leu missense_variant 0.91 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.97 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.97 streptomycin
rpsL 781616 c.57C>T synonymous_variant 0.97 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 0.98 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.98 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.98 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.98 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.98 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.98 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.96 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.95 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.95 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.96 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>G synonymous_variant 0.96 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.96 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.95 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.95 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.95 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>G synonymous_variant 0.96 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.96 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.96 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.96 streptomycin
rpsL 781883 c.324G>A synonymous_variant 0.95 streptomycin
rpsL 781886 c.327C>T synonymous_variant 0.95 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.98 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.98 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 1.0 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 0.97 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.98 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.98 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.97 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.97 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 0.97 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.99 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.99 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 0.99 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.99 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.99 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.99 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.98 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.97 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 0.97 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.97 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.97 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 0.95 linezolid
rplC 800806 c.-3G>T upstream_gene_variant 0.95 linezolid
rplC 800807 c.-2_-1insT upstream_gene_variant 0.95 linezolid
rplC 800814 c.6A>G synonymous_variant 0.95 linezolid
rplC 800815 c.7C>A synonymous_variant 0.95 linezolid
rplC 800820 c.12G>A synonymous_variant 0.95 linezolid
rplC 800829 c.21C>G synonymous_variant 0.95 linezolid
rplC 800844 c.36T>C synonymous_variant 0.97 linezolid
rplC 800856 c.48A>G synonymous_variant 0.96 linezolid
rplC 800865 c.57A>G synonymous_variant 0.95 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.93 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.92 linezolid
rplC 800877 c.69A>C synonymous_variant 0.92 linezolid
rplC 800880 c.72A>G synonymous_variant 0.92 linezolid
rplC 800901 c.93C>G synonymous_variant 0.94 linezolid
rplC 800910 c.102C>T synonymous_variant 0.94 linezolid
rplC 800913 c.105G>A synonymous_variant 0.94 linezolid
rplC 800916 c.108A>G synonymous_variant 0.94 linezolid
rplC 800919 c.111C>G synonymous_variant 0.94 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 801372 c.564G>A synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 0.92 linezolid
rplC 801405 c.597T>C synonymous_variant 0.92 linezolid
rplC 801408 c.600C>A synonymous_variant 0.92 linezolid
rplC 801423 c.615G>C synonymous_variant 0.92 linezolid
rplC 801426 c.618C>T synonymous_variant 0.92 linezolid
rplC 801427 p.Met207Val missense_variant 0.92 linezolid
rplC 801437 p.Ser210Thr missense_variant 0.92 linezolid
fbiC 1303449 c.519C>T synonymous_variant 0.7 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303470 c.540T>G synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303538 p.Arg203Leu missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303596 c.666G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304019 c.1089C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304532 c.1602G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304541 c.1611C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304797 p.Ala623Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304871 c.1941G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1943delAGinsTC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305039 c.2109G>A synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
sigE 1364703 c.291G>C synonymous_variant 0.82 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.86 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.86 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 0.86 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.9 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.9 pyrazinamide
sigE 1364745 c.333C>T synonymous_variant 0.9 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
sigE 1364751 c.339C>G synonymous_variant 0.95 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.96 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.96 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.96 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.95 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.95 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.95 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.95 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.96 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 0.94 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 0.94 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.89 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
sigE 1364892 c.480C>G synonymous_variant 0.89 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.95 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.94 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.88 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 0.88 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.82 pyrazinamide
embR 1416285 p.Glu355Gln missense_variant 0.8 ethambutol
embR 1416289 c.1059G>A synonymous_variant 0.91 ethambutol
embR 1416301 c.1047C>A synonymous_variant 0.87 ethambutol
embR 1416310 c.1038G>C synonymous_variant 0.95 ethambutol
embR 1416313 c.1035A>G synonymous_variant 0.95 ethambutol
embR 1416316 c.1032C>G synonymous_variant 1.0 ethambutol
embR 1416330 p.Val340Ile missense_variant 1.0 ethambutol
embR 1416332 p.Tyr339Phe missense_variant 1.0 ethambutol
embR 1416335 p.Asn338Ser missense_variant 1.0 ethambutol
embR 1416343 c.1005G>C synonymous_variant 1.0 ethambutol
embR 1416364 c.984C>T synonymous_variant 0.95 ethambutol
atpE 1460807 c.-238C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460828 c.-217C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.96 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.93 bedaquiline
atpE 1460895 c.-150_-148delGCAinsTC upstream_gene_variant 0.93 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 0.93 bedaquiline
atpE 1460904 c.-141C>T upstream_gene_variant 0.93 bedaquiline
atpE 1460918 c.-127A>G upstream_gene_variant 0.91 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 0.97 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 0.97 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.97 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473449 n.-209G>A upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473454 n.-204A>G upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473659 n.2T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473918 n.261C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473943 n.286G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsAT non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473994 n.337C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474011 n.354G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474018 n.361G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474030 n.373G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474110 n.453A>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474409 n.756_774delACCCACACGCGCATACGCG non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474433 n.776G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474435 n.779_783delTGAAT non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474995 n.1338T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475007 n.1350C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475018 n.1361G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475404 n.1747A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475954 n.2297A>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
inhA 1673565 c.-637G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673865 c.-337C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 1.0 ethionamide
isoniazid
inhA 1673877 c.-325C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674507 c.306G>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674537 c.336C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674588 c.387G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674619 p.Pro140Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674687 c.486G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674696 c.495G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674820 c.619_621delCTCinsTG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674888 c.687C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674939 c.738G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674942 c.741T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 0.94 ethionamide
isoniazid
inhA 1675006 c.805_807delCTCinsTG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
rpsA 1833277 c.-265C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 0.95 pyrazinamide
rpsA 1833288 c.-254_-253delTGinsCC upstream_gene_variant 0.95 pyrazinamide
rpsA 1833304 c.-238C>G upstream_gene_variant 0.92 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.93 pyrazinamide
rpsA 1833319 c.-223C>G upstream_gene_variant 0.93 pyrazinamide
rpsA 1833340 c.-202G>C upstream_gene_variant 0.95 pyrazinamide
rpsA 1833343 c.-199G>C upstream_gene_variant 0.88 pyrazinamide
rpsA 1833352 c.-190C>G upstream_gene_variant 0.73 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 0.93 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.96 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.99 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.99 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1833790 c.249T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833895 c.354G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833934 c.393C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833994 c.453G>A synonymous_variant 0.99 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>T synonymous_variant 0.98 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.99 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.99 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834318 c.777C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.98 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834603 c.1062G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 0.96 pyrazinamide
tsnR 1853369 c.-237C>T upstream_gene_variant 0.92 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.92 linezolid
tsnR 1853375 c.-231G>A upstream_gene_variant 0.92 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.93 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.92 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.91 linezolid
ndh 2101813 c.1230G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101825 c.1218G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101837 p.Ala402Val missense_variant 1.0 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102617 c.426C>T synonymous_variant 0.79 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102632 c.411C>T synonymous_variant 0.88 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102638 c.405A>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102674 c.369G>A synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102677 c.366C>G synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102711 p.Pro111Asp missense_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102723 p.Thr107Ser missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102863 c.180C>T synonymous_variant 0.9 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102869 c.174G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102872 c.171A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102878 c.165G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102883 c.160C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102895 c.148C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102902 c.141C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102908 c.135C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102914 c.129C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102919 c.124C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102938 p.Arg35His missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102959 c.84C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102962 c.81A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102971 c.72C>T synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102977 c.66T>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
katG 2155047 c.1065C>G synonymous_variant 1.0 isoniazid
katG 2155119 c.993T>C synonymous_variant 1.0 isoniazid
katG 2155131 c.981A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155134 c.978G>C synonymous_variant 1.0 isoniazid
katG 2155144 p.Asn323Pro missense_variant 1.0 isoniazid
katG 2155152 c.960A>G synonymous_variant 1.0 isoniazid
katG 2155155 c.957C>G synonymous_variant 1.0 isoniazid
katG 2155185 c.927T>C synonymous_variant 1.0 isoniazid
katG 2155188 p.Thr308Lys missense_variant 1.0 isoniazid
katG 2155191 c.921A>C synonymous_variant 1.0 isoniazid
katG 2155581 c.531C>A synonymous_variant 1.0 isoniazid
katG 2155587 c.525G>C synonymous_variant 1.0 isoniazid
katG 2155590 c.522A>G synonymous_variant 1.0 isoniazid
katG 2155614 c.498T>G synonymous_variant 1.0 isoniazid
katG 2155626 c.486G>C synonymous_variant 1.0 isoniazid
katG 2155632 c.480A>G synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155656 c.456G>A synonymous_variant 1.0 isoniazid
katG 2155661 p.Val151Ile missense_variant 1.0 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 c.417C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.98 isoniazid
kasA 2517965 c.-150C>T upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517983 c.-132T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 1.0 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 1.0 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 1.0 isoniazid
kasA 2518040 c.-75G>T upstream_gene_variant 1.0 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 1.0 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 1.0 isoniazid
kasA 2518053 c.-62_-60delATTinsCG upstream_gene_variant 1.0 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 1.0 isoniazid
kasA 2518085 c.-30C>T upstream_gene_variant 1.0 isoniazid
kasA 2518162 c.48G>A synonymous_variant 1.0 isoniazid
kasA 2518169 p.Val19Leu missense_variant 1.0 isoniazid
kasA 2518172 c.58_60delACAinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 1.0 isoniazid
kasA 2518199 p.Ile29Val missense_variant 1.0 isoniazid
kasA 2518219 c.105T>C synonymous_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.97 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.97 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 0.97 isoniazid
kasA 2518273 c.159G>A synonymous_variant 0.96 isoniazid
kasA 2518279 p.Asp55Glu missense_variant 0.94 isoniazid
kasA 2518282 c.168A>G synonymous_variant 0.93 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.93 isoniazid
kasA 2518289 p.Lys59Gln missense_variant 0.93 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.91 isoniazid
kasA 2518300 c.186T>A synonymous_variant 0.9 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.92 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.93 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.93 isoniazid
kasA 2518492 c.378C>T synonymous_variant 0.93 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.93 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.93 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.94 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.94 isoniazid
kasA 2518531 c.417G>A synonymous_variant 0.94 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.95 isoniazid
kasA 2518561 c.447T>C synonymous_variant 1.0 isoniazid
kasA 2518723 c.609G>A synonymous_variant 1.0 isoniazid
kasA 2518735 c.621C>T synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518768 c.654C>G synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>A synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>C synonymous_variant 1.0 isoniazid
kasA 2519293 c.1179T>C synonymous_variant 1.0 isoniazid
kasA 2519295 p.Tyr394Phe missense_variant 1.0 isoniazid
kasA 2519305 c.1191A>G synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
kasA 2519317 c.1203G>A synonymous_variant 1.0 isoniazid
kasA 2519338 c.1224T>C synonymous_variant 1.0 isoniazid
kasA 2519344 c.1230G>C synonymous_variant 1.0 isoniazid
kasA 2519347 c.1233T>C synonymous_variant 1.0 isoniazid
ahpC 2726591 c.399C>G synonymous_variant 0.91 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.92 isoniazid
ahpC 2726627 c.435G>A synonymous_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726654 c.462G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726657 c.465A>G synonymous_variant 1.0 isoniazid
ahpC 2726660 c.468C>T synonymous_variant 1.0 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 1.0 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 1.0 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 0.94 isoniazid
ahpC 2726690 c.498C>T synonymous_variant 0.93 isoniazid
ahpC 2726693 c.501C>T synonymous_variant 0.92 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.92 isoniazid
ahpC 2726699 c.507G>A synonymous_variant 0.93 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.91 isoniazid
folC 2747062 c.537A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2747098 c.501C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747132 p.Thr156Val missense_variant 1.0 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747137 c.462G>C synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2783224 c.819C>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783251 c.792G>A synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783266 c.777C>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783281 c.762G>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>A synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783320 c.723C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783347 c.696C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783427 p.Pro206Ala missense_variant 0.98 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783431 c.612C>T synonymous_variant 0.98 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783437 c.606G>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783458 c.585G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.99 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783578 c.465G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783602 c.441G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783623 c.420G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783632 c.411C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin