Run ID: ERR3797061
Sample name:
Date: 2024-04-14T04:49:14.379300
Number of reads: 264468
Percentage reads mapped: 35.22
Median coverage: 11.0
Strain: La1.6;La3;lineage4.9
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.9 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.95 |
| La1.7.1 | M.bovis | None | 0.06 |
| La3 | M.orygis | None | 0.06 |
| La1.6 | M.bovis | None | 0.07 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | pepQ | c.592_594delGCCinsCG | Assoc w R - Interim | |
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| fbiC | c.916_918delTTCinsAG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| bedaquiline | pepQ | c.592_594delGCCinsCG | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV |
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303846 | c.916_918delTTCinsAG | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| pepQ | 2859825 | c.592_594delGCCinsCG | frameshift_variant&synonymous_variant | 0.93 | clofazimine | Assoc w R - Interim | |
| bedaquiline | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV | |||||
| embB | 4247580 | p.Ala356Val | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1113 | c.1113A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1122 | c.1122C>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1125 | c.1125G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1128 | c.1128G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1149 | c.1149C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1153 | c.1153T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1164 | c.1164A>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1167 | c.1167A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1176 | c.1176A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1203 | c.1203T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1210 | p.Ala404Ser | missense_variant | 1.0 | isoniazid | |
| dnaA | 1220 | p.Asn407Ser | missense_variant | 1.0 | isoniazid | |
| gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6103 | c.864G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6121 | c.882C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6209 | c.970C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6223 | c.984G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6229 | c.990G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6247 | c.1008G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6772 | c.1533C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6778 | c.-524C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6805 | c.1566G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6808 | c.1569C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6850 | c.-452C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6869 | c.-433T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6901 | c.-401G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6919 | c.1680T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6931 | c.1692A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6943 | c.-359G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6970 | c.-332C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6994 | c.-308C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7021 | c.-281G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7412 | c.111C>G | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>T | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7520 | c.219G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8360 | c.1059G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8402 | p.Asp367Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8468 | c.1167C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8573 | c.1272G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8595 | p.Ala432Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8618 | c.1317G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8816 | c.1515C>T | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 0.92 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8954 | c.1653G>A | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8965 | c.1664_1665insG | frameshift_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8968 | c.1668delG | frameshift_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>T | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9344 | c.2043C>T | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 490887 | c.105G>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490896 | c.114C>T | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490902 | c.120T>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491082 | c.300T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491091 | c.309T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491137 | p.Glu119Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491144 | p.Ala121Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491169 | c.387C>T | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491292 | c.510G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491302 | p.Ile174Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491331 | c.549G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491340 | c.558C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491343 | c.561C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491355 | c.573C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 574724 | c.-624T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574731 | c.-617A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574739 | c.-609T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574742 | c.-606G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574763 | c.-585T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 575587 | c.240C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575590 | c.243T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575629 | c.282A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575632 | c.285G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575635 | c.288A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575641 | c.294A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575649 | p.Val101Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 620160 | c.270A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620167 | p.Ala93Thr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620170 | p.Cys94Ser | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620173 | p.Val95Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620187 | c.297C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620198 | p.Gln103Leu | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620257 | p.Ile123Leu | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620269 | p.Val127Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620275 | c.385C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | p.Ala132Pro | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620295 | c.405G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620307 | c.417C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620319 | c.429C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| Rv0565c | 656282 | c.1189C>T | synonymous_variant | 0.9 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656358 | c.1113T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656364 | c.1107T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656367 | c.1104G>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656370 | c.1101T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656380 | p.Glu364Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656391 | c.1078_1080delCTCinsAG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656396 | p.Ser359Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656403 | c.1068C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656412 | c.1059T>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656418 | c.1053A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656423 | c.1048T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656447 | p.Ile342Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656448 | c.1023T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656454 | c.1017G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656457 | c.1014T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656469 | c.1002T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656476 | p.Lys332Ala | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656481 | c.990A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656484 | c.987T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656487 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656502 | c.969C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656511 | c.960T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656539 | p.Ser311Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656542 | p.Thr310Ser | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656546 | p.Ile309Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
| hadA | 732389 | p.Ser154Thr | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
| nusG | 734147 | c.-107T>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734156 | c.-98C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734183 | c.-71C>T | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734186 | c.-68G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734193 | c.-61A>G | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734205 | c.-49A>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734409 | c.156T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734466 | c.213G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734470 | c.217_219delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| nusG | 734502 | c.249G>A | synonymous_variant | 0.94 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| nusG | 734800 | p.Val183Ile | missense_variant | 1.0 | rifampicin | |
| nusG | 734814 | c.561G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734826 | c.573A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734841 | c.588G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734865 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734870 | p.Ser206Asn | missense_variant | 1.0 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734913 | c.660C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760454 | c.648C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 0.9 | rifampicin | |
| rpoB | 760934 | c.1128C>G | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760958 | c.1152G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 0.88 | rifampicin | |
| rpoB | 761171 | c.1365C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761196 | c.1390C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761273 | c.1467T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761309 | c.1503C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoB | 761540 | c.1734C>G | synonymous_variant | 0.83 | rifampicin | |
| rpoB | 761552 | c.1746G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoB | 761720 | c.1915_1916delGA | frameshift_variant | 0.91 | rifampicin | |
| rpoB | 761724 | p.Glu640Thr | missense_variant | 0.91 | rifampicin | |
| rpoB | 761728 | c.1923_1924insCC | frameshift_variant | 0.91 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 0.9 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761819 | c.2013G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761840 | c.2034C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761876 | c.2070C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761913 | c.2107_2109delGACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761921 | c.2115C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761969 | c.2163G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762011 | c.2205G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762020 | c.2214G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762023 | c.2217C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762119 | c.2313C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762218 | c.2412T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762297 | c.2491C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763052 | c.-318G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763076 | c.-294C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763082 | c.-288C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763184 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763268 | c.-102C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763537 | c.168C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763600 | c.231C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763648 | c.279C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763714 | c.345G>A | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 763744 | c.375G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763768 | c.399C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 763790 | c.421_423delGAGinsAC | frameshift_variant&missense_variant | 0.94 | rifampicin | |
| rpoC | 763801 | c.432C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763816 | c.447C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 0.96 | rifampicin | |
| rpoC | 763851 | p.Ala161Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 763855 | c.486C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763871 | p.Gly168Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763927 | c.558C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763948 | c.579G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763963 | c.594C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763978 | c.609C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764071 | c.702G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764110 | c.741C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764188 | c.819A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764203 | c.834G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 0.95 | rifampicin | |
| rpoC | 764217 | p.Asn283Ser | missense_variant | 0.95 | rifampicin | |
| rpoC | 764245 | c.876C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764467 | c.1098C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764533 | c.1164C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764551 | c.1182G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.91 | rifampicin | |
| rpoC | 764656 | c.1287C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764695 | c.1326T>C | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764749 | c.1380G>C | synonymous_variant | 0.82 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.82 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
| rpoC | 764830 | c.1461C>G | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764851 | c.1482C>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 764858 | c.1489_1491delTTGinsCA | frameshift_variant&missense_variant | 0.9 | rifampicin | |
| rpoC | 764861 | c.1492C>T | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 764867 | c.1498_1500delCGCinsAG | frameshift_variant&missense_variant | 0.9 | rifampicin | |
| rpoC | 764875 | c.1506C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 0.82 | rifampicin | |
| rpoC | 764881 | c.1512G>C | synonymous_variant | 0.82 | rifampicin | |
| rpoC | 764885 | c.1516_1518delCGGinsAA | frameshift_variant&missense_variant | 0.82 | rifampicin | |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 0.82 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoC | 765223 | c.1854G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765232 | c.1863G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765247 | c.1878C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765278 | c.1909C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765292 | c.1923G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765307 | c.1938C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 765583 | c.2214G>T | synonymous_variant | 0.92 | rifampicin | |
| rpoC | 765612 | p.His748Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 765673 | p.Asp768Glu | missense_variant | 0.94 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 0.95 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765823 | c.2454C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765934 | c.2565C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765985 | c.2616C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766009 | c.2640G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766054 | c.2685C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766063 | c.2694C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766081 | c.2712T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766084 | c.2715A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766085 | p.Pro906Ala | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766142 | c.2773C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766148 | p.Thr927Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766285 | c.2916C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766312 | c.2943T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766627 | c.3258G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766658 | p.Arg1097Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766978 | c.3609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767032 | c.3663G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767152 | c.3783T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767188 | c.3819G>A | synonymous_variant | 1.0 | rifampicin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781820 | c.261G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781835 | c.276T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 0.91 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.92 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.92 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800684 | c.-125G>A | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800690 | c.-119C>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800799 | c.-10_-8delGGAinsC | upstream_gene_variant | 0.95 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 0.96 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 0.95 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 0.94 | linezolid | |
| rplC | 800874 | c.66A>G | synonymous_variant | 0.94 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 0.94 | linezolid | |
| rplC | 800880 | c.72A>C | synonymous_variant | 0.94 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 0.94 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801201 | c.393C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801267 | c.459A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801288 | c.480G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801315 | c.507G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801339 | c.531T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801432 | c.624C>G | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303242 | c.312T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303248 | c.318G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303268 | p.Lys113Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303623 | c.693C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303638 | c.708A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303660 | p.Val244Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303731 | c.801A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303732 | p.Ser268Pro | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303749 | c.819G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303755 | c.825T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303789 | p.Ile287Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303794 | c.864A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303806 | c.876G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303809 | c.879G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303821 | c.891C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303860 | c.930A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303869 | c.939T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303884 | c.954T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303905 | c.975G>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303920 | c.990C>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303935 | c.1005G>A | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303947 | c.1017T>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303956 | c.1026A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303965 | c.1035G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303969 | p.Val347Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303989 | c.1059C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303998 | c.1068T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304001 | c.1071C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304031 | c.1101C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304058 | p.Glu376Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304067 | c.1137G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304070 | c.1140C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304091 | p.Asp387Glu | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304096 | p.Val389Ala | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304115 | c.1185A>G | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304127 | c.1197A>C | synonymous_variant | 0.92 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304133 | c.1203G>C | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304136 | c.1206C>G | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304169 | c.1239T>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304172 | c.1242G>T | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304637 | c.1707G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304671 | p.Val581Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304675 | p.Gly582Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304694 | c.1764A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304799 | c.1869G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304853 | c.1923C>T | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304883 | p.Glu651Asp | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304913 | c.1983G>A | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304970 | c.2040G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305033 | c.2103T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305042 | c.2112A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305045 | c.2115A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305066 | c.2136T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305069 | c.2139G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305074 | p.Ser715Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305078 | c.2148A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305090 | c.2160C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305096 | c.2166T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305099 | c.2169T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305114 | p.Asp728Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305117 | c.2187T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305126 | c.2196T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1305135 | c.2205C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305150 | c.2220C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305154 | c.2224T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305159 | c.2229G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305177 | c.2247A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305181 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305186 | c.2256C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305273 | c.2343C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305276 | c.2346G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364766 | c.354C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364772 | c.360G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461137 | c.93C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461150 | c.106_108delATCinsGT | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| atpE | 1461155 | c.111C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461159 | p.Val39Ile | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| atpE | 1461182 | c.138A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461189 | c.145C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.89 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.89 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.9 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.9 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Not assoc w R | |||||
| rrl | 1474040 | n.383G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474060 | n.403G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474089 | n.432C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474249 | n.592G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474950 | n.1293G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474952 | n.1296_1300delCATCC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474962 | n.1305T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474967 | n.1311_1315delGGGTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474997 | n.1340A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475006 | n.1349A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475253 | n.1596T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475273 | n.1616T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475289 | n.1632G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475363 | n.1706C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475366 | n.1709G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475409 | n.1752T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475532 | n.1875A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475606 | n.1949T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475617 | n.1960C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475625 | n.1968G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475626 | n.1969T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475639 | n.1982C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475655 | n.1998T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475883 | n.2226A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476035 | n.2378G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1674471 | c.270G>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674486 | c.285T>C | synonymous_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674489 | c.288G>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674503 | p.Thr101Ser | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674550 | p.Ser117Ala | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674570 | c.369G>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674576 | c.375T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674628 | p.Ser143Gly | missense_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674654 | c.453G>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674660 | c.459G>T | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674663 | c.462G>C | synonymous_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674714 | c.513C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674726 | c.525G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674729 | c.528G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674750 | c.549T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674765 | c.564C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674771 | c.570C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674777 | c.576C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674792 | c.591G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674816 | c.615T>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674825 | c.624C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674846 | c.645C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674849 | p.Gln216His | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | c.703_705delGCGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674957 | c.756G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674966 | c.765T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674967 | p.Asp256Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674970 | p.Ile257Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674993 | c.792G>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674994 | p.His265Ser | missense_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833541 | c.-1T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1833578 | p.Val13Ile | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833613 | c.72C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833625 | c.84A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833673 | c.132C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834411 | c.870T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834432 | c.891G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.92 | pyrazinamide | |
| rpsA | 1834474 | c.933C>G | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834654 | p.Glu371Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834788 | p.Ala416Gly | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853360 | c.-246G>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| bacA | 2064936 | c.-208C>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064948 | c.-220G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064952 | c.-224T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064969 | c.-241T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064972 | c.-244T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064978 | c.-250G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064979 | c.-253_-251delGGCinsCT | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064984 | c.-256A>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064993 | c.-265T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2065005 | c.-277C>T | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| ndh | 2101795 | c.1248G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101804 | c.1239T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101838 | p.Ala402Val | missense_variant | 0.93 | ethionamide | Uncertain significance |
| delamanid | ||||||
| isoniazid | Uncertain significance | |||||
| ndh | 2101858 | p.Ile395Met | missense_variant | 0.94 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101873 | c.1170T>C | synonymous_variant | 0.94 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101888 | c.1153_1155delGTTinsCG | frameshift_variant&missense_variant | 0.93 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2101891 | c.1152C>G | synonymous_variant | 0.94 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101912 | c.1131G>C | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101920 | c.1123A>C | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101924 | c.1119T>G | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101936 | c.1107G>C | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101939 | c.1104A>G | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101960 | c.1083A>C | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101970 | p.Glu358Ala | missense_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101980 | p.Asn355Asp | missense_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101984 | c.1059C>G | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101988 | p.Ala352Gly | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101990 | c.1053G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102009 | p.Ser345Asn | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102020 | c.1023A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102023 | c.1020G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102026 | c.1017G>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102050 | c.993T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102059 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102065 | c.978G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102068 | c.975T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102247 | p.Val266Ile | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102269 | c.774C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102287 | c.756C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102311 | c.732G>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102317 | c.726A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102320 | c.723G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102341 | c.702C>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102344 | c.699T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102366 | p.Ala226Glu | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102377 | c.666A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102382 | c.661C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102389 | c.654G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102392 | c.651C>G | synonymous_variant | 0.94 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102401 | c.642T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102407 | c.636T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102425 | c.618G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102443 | c.600A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102446 | c.597C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102454 | c.589T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102455 | c.588G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102680 | c.363T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102683 | c.360T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102712 | p.Pro111Ser | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102718 | p.Gln109Glu | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| pncA | 2289928 | c.-687C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289961 | c.-720C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289964 | c.-723C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289970 | c.-729C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289994 | c.-753A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289997 | c.-756G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290006 | c.-765T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290009 | c.-768A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290015 | c.-774A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290030 | c.-791_-789delAATinsCC | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290034 | c.-794_-793delGCinsAG | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290042 | c.-801T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290072 | c.-831T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| kasA | 2517920 | c.-195G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518226 | p.Ala38Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2518245 | p.His44Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518279 | c.165T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518571 | p.Val153Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518579 | c.465T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518594 | c.480C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518603 | c.489G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518627 | c.513T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518657 | c.543G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518663 | c.549T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518681 | c.567C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518697 | p.Cys195Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518717 | c.603C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| eis | 2715706 | c.-374G>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715709 | c.-377C>T | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715715 | c.-383G>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| folC | 2747007 | p.Ser198Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747011 | c.588G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747023 | c.576C>G | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747032 | c.567A>G | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747036 | p.Asn188Ser | missense_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747059 | c.540T>G | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747062 | c.537A>T | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747070 | p.Met177Leu | missense_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747074 | c.525G>C | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747086 | c.513A>G | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747089 | c.510G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747302 | c.297A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747341 | c.258C>G | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747359 | c.240C>G | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| folC | 2747365 | c.234G>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| folC | 2747371 | c.228C>G | synonymous_variant | 0.93 | para-aminosalicylic_acid | |
| folC | 2747395 | c.204T>C | synonymous_variant | 0.92 | para-aminosalicylic_acid | |
| folC | 2747407 | c.192T>C | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| folC | 2747412 | p.Ser63Gly | missense_variant | 0.9 | para-aminosalicylic_acid | |
| folC | 2747414 | p.Arg62Leu | missense_variant | 0.9 | para-aminosalicylic_acid | |
| folC | 2747419 | c.180C>G | synonymous_variant | 0.9 | para-aminosalicylic_acid | |
| Rv2477c | 2782913 | p.Ser377Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782927 | p.Thr372Gln | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782981 | c.1062G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783017 | c.1026C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783020 | c.1023G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783116 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783140 | c.903C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783167 | c.876G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783407 | c.636C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | c.618C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783499 | c.544T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783510 | p.Pro178His | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783557 | c.486T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783569 | c.474C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783620 | c.423C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783659 | p.Glu128Asp | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783680 | c.363G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | c.244_246delGACinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | p.Asp61Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783872 | c.171G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Phe | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| pepQ | 2859732 | c.687C>T | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859735 | c.684G>C | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859747 | c.672C>G | synonymous_variant | 0.91 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859765 | c.654G>C | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859778 | p.Val214Ala | missense_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859781 | p.Gln213Ala | missense_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859793 | p.Asp209Gly | missense_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859801 | c.618G>C | synonymous_variant | 0.92 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859834 | c.585T>C | synonymous_variant | 0.93 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| pepQ | 2859852 | c.567A>G | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859855 | c.564G>C | synonymous_variant | 0.93 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859864 | c.555T>G | synonymous_variant | 0.94 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| pepQ | 2859870 | c.549T>C | synonymous_variant | 0.94 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859873 | c.546T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859908 | p.Gln171Glu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859909 | c.510G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859918 | c.501A>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859921 | c.498C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859924 | c.495G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859942 | c.477C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| Rv2681 | 2997053 | c.315C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997054 | p.Ser106Gly | missense_variant | 1.0 | capreomycin | Uncertain significance |
| Rv2681 | 2997060 | p.Asn108Asp | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997065 | c.327G>A | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997092 | c.354T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997101 | c.363T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997104 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997116 | c.378T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997122 | c.384A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| Rv2681 | 2997125 | c.387G>A | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997128 | c.390A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997134 | c.396A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2752c | 3065436 | c.756A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065442 | c.750T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065449 | p.Ile248Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065457 | c.735A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065463 | c.729T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065481 | c.711T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065484 | c.708G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065487 | c.705T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065490 | c.702A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065493 | c.699G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065496 | c.696G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065499 | c.693A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065508 | c.684T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065517 | c.675C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065531 | p.Thr221Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065532 | c.660A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065541 | c.651A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065553 | c.639A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067304 | c.642A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067406 | c.540A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073950 | c.522G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074349 | c.123T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074360 | c.112T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074361 | c.111T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074364 | c.108T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| ald | 3087671 | c.852C>T | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087751 | p.Tyr311Phe | missense_variant | 1.0 | cycloserine | |
| Rv3236c | 3612667 | c.450T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612676 | c.441A>G | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612685 | c.432C>T | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612694 | c.421_423delCGTinsGC | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | Uncertain significance |
| Rv3236c | 3612708 | c.409T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612712 | c.405G>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612721 | c.396G>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612730 | c.387C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| Rv3236c | 3612736 | c.381T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612757 | p.Gly120Ala | missense_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612760 | c.357C>G | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612769 | c.348T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612772 | c.345T>A | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612786 | c.331T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612787 | c.330T>G | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612796 | c.321G>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612805 | c.312T>C | synonymous_variant | 1.0 | pyrazinamide | |
| lpqB | 3623372 | c.1539G>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R | |||||
| lpqB | 3623379 | p.Ala511Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623388 | p.Thr508Ile | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623393 | c.1518A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623411 | c.1500T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623432 | c.1479G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623442 | p.Ser490Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623444 | c.1467T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623450 | c.1461G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623468 | c.1443T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623480 | c.1431C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623484 | p.Phe476Tyr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623492 | c.1419T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623512 | p.Gly467Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623532 | p.Gly460Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623561 | c.1350T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623570 | c.1341A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623573 | c.1338T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623576 | c.1335T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623580 | p.Asn444Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623587 | p.Ala442Pro | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623591 | c.1320G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623598 | p.Arg438Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623602 | p.Ser437Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623614 | p.Thr433Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623615 | c.1296G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623627 | c.1284T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623633 | c.1278G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623654 | p.Asp419Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623660 | c.1251A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623666 | c.1245A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623676 | p.Val412Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623682 | p.Thr410Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623684 | c.1227T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623723 | c.1188C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623731 | p.Ser394Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623736 | p.Ser392Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623739 | p.His391Arg | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3623756 | c.1155G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624026 | c.885G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624032 | c.879T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624041 | p.Glu290Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624050 | c.861C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624077 | c.834G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624089 | c.822C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624094 | c.817A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624100 | c.811T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624101 | c.810C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624107 | c.804C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624125 | c.786A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624155 | c.756G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624242 | c.669A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624245 | c.666A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624464 | c.447A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624542 | c.369G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624545 | c.366T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624551 | c.360G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624557 | c.354T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624560 | c.351G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624563 | c.348C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624572 | c.339C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624575 | c.336T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624594 | p.Val106Ala | missense_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624603 | p.Lys103Arg | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624605 | c.306G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624612 | p.Ser100Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624614 | c.297A>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624623 | c.288C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624629 | c.282G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624646 | c.265T>C | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624649 | c.262T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624680 | c.231T>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624686 | c.223_225delGAAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624701 | c.210T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624707 | c.204G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624722 | c.189C>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624728 | c.183C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624755 | c.154_156delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624770 | c.141T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624776 | c.135T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624783 | p.Ser43Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624788 | c.123A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625186 | c.-276T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625189 | c.1425A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625255 | c.-345T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625258 | c.-348G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625285 | c.-375G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625528 | c.-618G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625592 | p.Ser341Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625616 | p.Arg333Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625675 | c.-765G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625717 | c.-807C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625762 | c.852A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625978 | c.636T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625988 | p.Thr209Gln | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625999 | c.615A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626095 | p.Glu173Asp | missense_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626101 | p.Gln171His | missense_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626349 | p.Ser89Gly | missense_variant | 0.77 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626353 | c.261C>A | synonymous_variant | 0.77 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626362 | c.252A>G | synonymous_variant | 0.77 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626377 | p.Asp79Glu | missense_variant | 0.86 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626383 | c.231G>C | synonymous_variant | 0.87 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626386 | c.228G>C | synonymous_variant | 0.87 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626390 | p.Arg75Lys | missense_variant | 0.87 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626400 | p.Ile72Val | missense_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626404 | c.210C>G | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626407 | c.207C>G | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626410 | c.204T>G | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626413 | c.201T>C | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626437 | c.177T>C | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626443 | c.171T>C | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626449 | c.165G>C | synonymous_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626455 | c.159C>G | synonymous_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.9 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626996 | c.-383G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.91 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 0.92 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627059 | c.-446G>C | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 0.93 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 0.92 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627101 | c.-488C>G | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627170 | c.-557C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627173 | c.-560G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627188 | c.160_162delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627212 | c.-599C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627218 | c.-605G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627236 | c.-623T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627287 | c.-674C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| alr | 3840356 | c.1063_1065delCTTinsGC | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| alr | 3840360 | p.Pro354Gln | missense_variant | 1.0 | cycloserine | |
| alr | 3840380 | c.1039_1041delATGinsCC | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| alr | 3840407 | c.1014G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840460 | p.Ser321Thr | missense_variant | 1.0 | cycloserine | |
| alr | 3840476 | c.945A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840482 | c.939T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841055 | c.366C>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841064 | c.357C>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841340 | c.-8989_80del | frameshift_variant | 1.0 | cycloserine | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877685 | c.823C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877889 | p.Ala207Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877909 | p.Asn200Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877950 | c.558C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878046 | c.462T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878094 | c.414C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878199 | c.309T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878361 | c.147G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878409 | c.99C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878430 | c.78G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878869 | c.-362G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879130 | c.-623A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879202 | c.-695T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 1.0 | rifampicin | |
| clpC1 | 4038278 | c.2427T>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038308 | c.2397G>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038314 | c.2391T>A | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038395 | c.2310C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038494 | c.2211G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038559 | p.Ile716Val | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038560 | p.Asp715Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038587 | c.2118C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039031 | c.1674T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039037 | c.1668T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039268 | c.1437C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039277 | c.1428C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039304 | c.1401G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039331 | c.1374C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039346 | c.1359G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039406 | c.1299G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039574 | c.1129_1131delGCGinsTC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039621 | c.1084C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039679 | c.1026C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039823 | c.882T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039925 | c.780C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040090 | c.615T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.92 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>C | synonymous_variant | 0.9 | pyrazinamide | |
| clpC1 | 4040234 | c.471C>T | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>T | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040336 | c.369G>T | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 0.91 | pyrazinamide | |
| clpC1 | 4040528 | c.177G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044725 | c.-444C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044737 | c.-456T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044752 | c.-471T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044755 | c.-474G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044758 | c.-477C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044809 | c.-528C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044812 | c.-531A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044818 | c.-539_-537delCCGinsGC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044822 | c.-541G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044844 | c.-563T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| glpK | 4138670 | c.1086G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138681 | p.Met359Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138682 | c.1074C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138685 | c.1071C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138696 | p.Pro354Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138703 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138709 | c.1047G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138714 | p.Ala348Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138730 | c.1026C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138772 | c.984G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138796 | c.960A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138817 | c.939T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138829 | c.927A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138832 | c.924C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138835 | c.921C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138841 | c.915G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138847 | c.909A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138858 | p.Asn300His | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138859 | c.897T>C | synonymous_variant | 0.92 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138862 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138871 | c.885C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138877 | c.879A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138880 | c.876T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138889 | c.867G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4239426 | c.-437_-435delCCAinsGC | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239432 | c.-431A>G | upstream_gene_variant | 0.91 | ethambutol | |
| embC | 4239437 | c.-426T>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4240105 | c.243C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240111 | c.249C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240120 | c.258C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240141 | c.279A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240154 | c.293_301delAGAACACCG | disruptive_inframe_deletion | 1.0 | ethambutol | |
| embC | 4240165 | c.305_307delAGA | disruptive_inframe_deletion | 1.0 | ethambutol | |
| embC | 4240178 | c.316T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240183 | c.321A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240201 | c.339G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240204 | c.342T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240807 | c.945C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240816 | c.954C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240828 | c.966G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240858 | c.996G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240867 | c.1005T>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240870 | c.1008T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240879 | c.1017G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240880 | p.Ala340Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4240885 | c.1023T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240897 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240898 | c.1036C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240911 | p.Ala350Val | missense_variant | 1.0 | ethambutol | |
| embC | 4240921 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240936 | c.1074A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241107 | c.1245G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 0.91 | ethambutol | Not assoc w R - Interim |
| embC | 4241707 | c.1845G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241713 | c.1851G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241719 | c.1857G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241736 | p.Val625Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241741 | c.1879_1881delGTCinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4241747 | p.Val629Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241750 | c.1888_1890delTTGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4241755 | c.1893C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241770 | c.1908T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244588 | c.1356G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244611 | p.Ala460Val | missense_variant | 1.0 | ethambutol | |
| embA | 4244615 | c.1383G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244616 | p.Ala462Ser | missense_variant | 1.0 | ethambutol | |
| embA | 4244633 | c.1401C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244645 | c.1413T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244648 | c.1416G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244649 | p.Asp473Ser | missense_variant | 1.0 | ethambutol | |
| embA | 4244669 | c.1437G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244675 | c.1443A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244681 | c.1449A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244708 | c.1476C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244726 | p.Asp498Glu | missense_variant | 1.0 | ethambutol | |
| embA | 4244728 | p.Phe499Trp | missense_variant | 1.0 | ethambutol | |
| embA | 4244747 | c.1515T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244756 | c.1524G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244764 | p.Val511Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4244771 | c.1539G>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244780 | c.1548C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244783 | c.1551C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244792 | c.1560G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244802 | p.Leu524Met | missense_variant | 1.0 | ethambutol | |
| embA | 4244808 | c.1576_1578delTTCinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4244823 | p.Val531Met | missense_variant | 1.0 | ethambutol | |
| embA | 4244829 | c.1597_1599delTTCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245053 | c.1821G>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245056 | c.1824C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245125 | c.1893G>C | synonymous_variant | 0.91 | ethambutol | |
| embA | 4245128 | c.1896G>C | synonymous_variant | 0.91 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 0.92 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245206 | c.1974A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245217 | p.Ala662Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245233 | c.2001G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245257 | c.2025A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245569 | p.Glu779Asp | missense_variant | 1.0 | ethambutol | |
| embB | 4245575 | c.-939C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245593 | c.-921C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245620 | c.-894T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245623 | c.-891G>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245674 | c.2442A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245677 | c.-837G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245719 | c.-795G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245725 | c.-789A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245726 | c.-788T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
| embB | 4247470 | c.957T>C | synonymous_variant | 0.94 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 0.96 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 0.94 | ethambutol | |
| embB | 4247550 | p.Ala346Asp | missense_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247567 | c.1054C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247602 | c.1089G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247957 | p.Met482Leu | missense_variant | 0.9 | ethambutol | |
| embB | 4247965 | c.1452C>G | synonymous_variant | 0.92 | ethambutol | |
| embB | 4247972 | p.Thr487Ser | missense_variant | 0.92 | ethambutol | |
| embB | 4247983 | c.1470G>C | synonymous_variant | 0.92 | ethambutol | |
| embB | 4248007 | c.1494C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248011 | p.Ser500Arg | missense_variant | 1.0 | ethambutol | |
| embB | 4248014 | p.Thr501Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4248055 | c.1542G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630_1632delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248173 | p.Val554Met | missense_variant | 1.0 | ethambutol | |
| embB | 4248178 | c.1665C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>G | synonymous_variant | 0.92 | ethambutol | Not assoc w R - Interim |
| embB | 4248252 | p.Gly580Ala | missense_variant | 0.91 | ethambutol | |
| embB | 4248277 | c.1764G>C | synonymous_variant | 0.9 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 0.9 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 0.9 | ethambutol | |
| embB | 4248322 | c.1809G>T | synonymous_variant | 0.9 | ethambutol | |
| aftB | 4269153 | c.-317C>G | upstream_gene_variant | 1.0 | ethambutol |
