TB-Profiler result

Run: ERR3797061

Summary

Run ID: ERR3797061

Sample name:

Date: 2024-04-14T04:49:14.379300

Number of reads: 264468

Percentage reads mapped: 35.22

Median coverage: 11.0

Strain: La1.6;La3;lineage4.9

Spoligotype:

Drug-resistance: Other


Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.9
lineage4.9 Euro-American (H37Rv-like) None 0.95
La1.7.1 M.bovis None 0.06
La3 M.orygis None 0.06
La1.6 M.bovis None 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.592_594delGCCinsCG Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.916_918delTTCinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.592_594delGCCinsCG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsAG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
pepQ 2859825 c.592_594delGCCinsCG frameshift_variant&synonymous_variant 0.93 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>T synonymous_variant 1.0 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 1.0 isoniazid
dnaA 1149 c.1149C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1210 p.Ala404Ser missense_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6229 c.990G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6772 c.1533C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6805 c.1566G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6850 c.-452C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6901 c.-401G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6943 c.-359G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8468 c.1167C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8573 c.1272G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8595 p.Ala432Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8618 c.1317G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8954 c.1653G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8965 c.1664_1665insG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8968 c.1668delG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9344 c.2043C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9345 c.2044A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
fgd1 490887 c.105G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491137 p.Glu119Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491169 c.387C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574724 c.-624T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574742 c.-606G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574763 c.-585T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575587 c.240C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575649 p.Val101Glu missense_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620160 c.270A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620167 p.Ala93Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620170 p.Cys94Ser missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620187 c.297C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620275 c.385C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656282 c.1189C>T synonymous_variant 0.9 ethionamide Not assoc w R - Interim
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656367 c.1104G>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656370 c.1101T>C synonymous_variant 1.0 ethionamide
Rv0565c 656380 p.Glu364Gly missense_variant 1.0 ethionamide
Rv0565c 656391 c.1078_1080delCTCinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656396 p.Ser359Gly missense_variant 1.0 ethionamide
Rv0565c 656403 c.1068C>G synonymous_variant 1.0 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 1.0 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 1.0 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 1.0 ethionamide
Rv0565c 656447 p.Ile342Val missense_variant 1.0 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 1.0 ethionamide
Rv0565c 656476 p.Lys332Ala missense_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656502 c.969C>T synonymous_variant 1.0 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656539 p.Ser311Asp missense_variant 1.0 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 1.0 ethionamide
Rv0565c 656546 p.Ile309Val missense_variant 1.0 ethionamide Uncertain significance
hadA 732389 p.Ser154Thr missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734156 c.-98C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734193 c.-61A>G upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734409 c.156T>C synonymous_variant 1.0 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>A synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734470 c.217_219delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 0.94 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734800 p.Val183Ile missense_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.94 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.94 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.95 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 1.0 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 0.9 rifampicin
rpoB 760934 c.1128C>G synonymous_variant 0.91 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.94 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.95 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.88 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 0.94 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761196 c.1390C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761309 c.1503C>T synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>G synonymous_variant 0.83 rifampicin
rpoB 761552 c.1746G>C synonymous_variant 0.91 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.94 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.93 rifampicin
rpoB 761720 c.1915_1916delGA frameshift_variant 0.91 rifampicin
rpoB 761724 p.Glu640Thr missense_variant 0.91 rifampicin
rpoB 761728 c.1923_1924insCC frameshift_variant 0.91 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.92 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.92 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.92 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.9 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761840 c.2034C>A synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762023 c.2217C>T synonymous_variant 1.0 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 c.2491C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 1.0 rifampicin
rpoC 763082 c.-288C>G upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763184 c.3378C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763268 c.-102C>A upstream_gene_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763537 c.168C>G synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>G synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>A synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 0.94 rifampicin
rpoC 763714 c.345G>A synonymous_variant 0.93 rifampicin
rpoC 763717 c.348T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763744 c.375G>C synonymous_variant 0.94 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.94 rifampicin
rpoC 763768 c.399C>G synonymous_variant 0.93 rifampicin
rpoC 763790 c.421_423delGAGinsAC frameshift_variant&missense_variant 0.94 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.95 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.95 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.95 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.96 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763871 p.Gly168Thr missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763927 c.558C>G synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 0.96 rifampicin
rpoC 763963 c.594C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 0.94 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.95 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.92 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.92 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.92 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.91 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.91 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.95 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.95 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.95 rifampicin
rpoC 764245 c.876C>G synonymous_variant 0.94 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.94 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.94 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.94 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.94 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764467 c.1098C>T synonymous_variant 0.92 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>G synonymous_variant 0.94 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 0.94 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 0.94 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.94 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.94 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.91 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.91 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 0.92 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.93 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.82 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.92 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.92 rifampicin
rpoC 764851 c.1482C>T synonymous_variant 0.92 rifampicin
rpoC 764858 c.1489_1491delTTGinsCA frameshift_variant&missense_variant 0.9 rifampicin
rpoC 764861 c.1492C>T synonymous_variant 0.9 rifampicin
rpoC 764867 c.1498_1500delCGCinsAG frameshift_variant&missense_variant 0.9 rifampicin
rpoC 764875 c.1506C>G synonymous_variant 0.9 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.82 rifampicin
rpoC 764881 c.1512G>C synonymous_variant 0.82 rifampicin
rpoC 764885 c.1516_1518delCGGinsAA frameshift_variant&missense_variant 0.82 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.82 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765223 c.1854G>C synonymous_variant 1.0 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 1.0 rifampicin
rpoC 765247 c.1878C>T synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765307 c.1938C>T synonymous_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Thr missense_variant 1.0 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.93 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.92 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.92 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.92 rifampicin
rpoC 765612 p.His748Arg missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765673 p.Asp768Glu missense_variant 0.94 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 0.95 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.95 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765823 c.2454C>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>G synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>G synonymous_variant 1.0 rifampicin
rpoC 766009 c.2640G>T synonymous_variant 1.0 rifampicin
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 1.0 rifampicin
rpoC 766054 c.2685C>T synonymous_variant 1.0 rifampicin
rpoC 766063 c.2694C>T synonymous_variant 1.0 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 1.0 rifampicin
rpoC 766084 c.2715A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766085 p.Pro906Ala missense_variant 1.0 rifampicin Not assoc w R
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766285 c.2916C>G synonymous_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766627 c.3258G>C synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767032 c.3663G>C synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>G synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767188 c.3819G>A synonymous_variant 1.0 rifampicin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>G synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781820 c.261G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800600 c.-209G>T upstream_gene_variant 0.91 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.92 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.92 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.94 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.94 linezolid
rplC 800690 c.-119C>G upstream_gene_variant 0.94 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.94 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.95 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>A upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10_-8delGGAinsC upstream_gene_variant 0.95 linezolid
rplC 800814 c.6A>G synonymous_variant 0.96 linezolid
rplC 800844 c.36T>C synonymous_variant 0.95 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.94 linezolid
rplC 800874 c.66A>G synonymous_variant 0.94 linezolid
rplC 800877 c.69A>C synonymous_variant 0.94 linezolid
rplC 800880 c.72A>C synonymous_variant 0.94 linezolid
rplC 800889 c.81C>G synonymous_variant 0.94 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 801201 c.393C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 0.92 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801315 c.507G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
rplC 801432 c.624C>G synonymous_variant 1.0 linezolid
fbiC 1303242 c.312T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303248 c.318G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303268 p.Lys113Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303806 c.876G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303809 c.879G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303821 c.891C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303965 c.1035G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303969 p.Val347Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303989 c.1059C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 1.0 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304064 c.1134G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304070 c.1140C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304096 p.Val389Ala missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>C synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304913 c.1983G>A synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305090 c.2160C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305114 p.Asp728Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364766 c.354C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364772 c.360G>T synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474060 n.403G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474997 n.1340A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475253 n.1596T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475273 n.1616T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475409 n.1752T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475626 n.1969T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475639 n.1982C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1674471 c.270G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 0.91 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.91 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.91 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.92 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 0.91 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674660 c.459G>T synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674765 c.564C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674825 c.624C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674846 c.645C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674849 p.Gln216His missense_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674957 c.756G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674970 p.Ile257Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 0.9 ethionamide
isoniazid
rpsA 1833541 c.-1T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1833578 p.Val13Ile missense_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833673 c.132C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834411 c.870T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834432 c.891G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.95 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834788 p.Ala416Gly missense_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 1.0 linezolid
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
bacA 2064936 c.-208C>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064952 c.-224T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-253_-251delGGCinsCT upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2065005 c.-277C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101795 c.1248G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101838 p.Ala402Val missense_variant 0.93 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2101888 c.1153_1155delGTTinsCG frameshift_variant&missense_variant 0.93 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101891 c.1152C>G synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101912 c.1131G>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101920 c.1123A>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101936 c.1107G>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101970 p.Glu358Ala missense_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101980 p.Asn355Asp missense_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101984 c.1059C>G synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101988 p.Ala352Gly missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102009 p.Ser345Asn missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102020 c.1023A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102023 c.1020G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102026 c.1017G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102050 c.993T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102059 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102065 c.978G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102068 c.975T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102247 p.Val266Ile missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102269 c.774C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102287 c.756C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102311 c.732G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102320 c.723G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102341 c.702C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102344 c.699T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102366 p.Ala226Glu missense_variant 1.0 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102377 c.666A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102382 c.661C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102389 c.654G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102392 c.651C>G synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102401 c.642T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102407 c.636T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102425 c.618G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102443 c.600A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102446 c.597C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102454 c.589T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102455 c.588G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102712 p.Pro111Ser missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 1.0 ethionamide
delamanid
isoniazid
pncA 2289928 c.-687C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289961 c.-720C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289964 c.-723C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289970 c.-729C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290006 c.-765T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 1.0 pyrazinamide
pncA 2290034 c.-794_-793delGCinsAG upstream_gene_variant 1.0 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290072 c.-831T>C upstream_gene_variant 1.0 pyrazinamide
kasA 2517920 c.-195G>A upstream_gene_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518226 p.Ala38Ser missense_variant 1.0 isoniazid
kasA 2518245 p.His44Arg missense_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.91 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518571 p.Val153Thr missense_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>G synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>G synonymous_variant 1.0 isoniazid
kasA 2518594 c.480C>G synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>A synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518657 c.543G>A synonymous_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518697 p.Cys195Ala missense_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518717 c.603C>G synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
eis 2715706 c.-374G>C upstream_gene_variant 1.0 amikacin
kanamycin
eis 2715709 c.-377C>T upstream_gene_variant 1.0 amikacin
kanamycin
eis 2715715 c.-383G>C upstream_gene_variant 1.0 amikacin
kanamycin
folC 2747007 p.Ser198Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747011 c.588G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747036 p.Asn188Ser missense_variant 0.92 para-aminosalicylic_acid
folC 2747059 c.540T>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747070 p.Met177Leu missense_variant 0.92 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747341 c.258C>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747365 c.234G>C synonymous_variant 0.94 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 0.93 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 0.9 para-aminosalicylic_acid
folC 2747412 p.Ser63Gly missense_variant 0.9 para-aminosalicylic_acid
folC 2747414 p.Arg62Leu missense_variant 0.9 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.9 para-aminosalicylic_acid
Rv2477c 2782913 p.Ser377Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783017 c.1026C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783167 c.876G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783407 c.636C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783432 p.Ser204Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783510 p.Pro178His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783569 c.474C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 p.Glu128Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 c.244_246delGACinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859732 c.687C>T synonymous_variant 0.9 clofazimine
bedaquiline
pepQ 2859735 c.684G>C synonymous_variant 0.9 clofazimine
bedaquiline
pepQ 2859747 c.672C>G synonymous_variant 0.91 clofazimine
bedaquiline
pepQ 2859765 c.654G>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859778 p.Val214Ala missense_variant 0.93 clofazimine
bedaquiline
pepQ 2859781 p.Gln213Ala missense_variant 0.93 clofazimine
bedaquiline
pepQ 2859793 p.Asp209Gly missense_variant 0.93 clofazimine
bedaquiline
pepQ 2859801 c.618G>C synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859834 c.585T>C synonymous_variant 0.93 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859852 c.567A>G synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859855 c.564G>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859864 c.555T>G synonymous_variant 0.94 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859870 c.549T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859873 c.546T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859908 p.Gln171Glu missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859909 c.510G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859918 c.501A>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859921 c.498C>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859924 c.495G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859942 c.477C>G synonymous_variant 1.0 clofazimine
bedaquiline
Rv2681 2997053 c.315C>G synonymous_variant 1.0 capreomycin
Rv2681 2997054 p.Ser106Gly missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997060 p.Asn108Asp missense_variant 1.0 capreomycin
Rv2681 2997065 c.327G>A synonymous_variant 1.0 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 1.0 capreomycin
Rv2681 2997101 c.363T>C synonymous_variant 1.0 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 1.0 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 1.0 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2997125 c.387G>A synonymous_variant 1.0 capreomycin
Rv2681 2997128 c.390A>G synonymous_variant 1.0 capreomycin
Rv2681 2997134 c.396A>G synonymous_variant 1.0 capreomycin
Rv2752c 3065436 c.756A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065442 c.750T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065449 p.Ile248Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065457 c.735A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065481 c.711T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065484 c.708G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065496 c.696G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065517 c.675C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065531 p.Thr221Ala missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065532 c.660A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065541 c.651A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065553 c.639A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067304 c.642A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073950 c.522G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074364 c.108T>C synonymous_variant 1.0 para-aminosalicylic_acid
ald 3087671 c.852C>T synonymous_variant 1.0 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 1.0 cycloserine
Rv3236c 3612667 c.450T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612676 c.441A>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612685 c.432C>T synonymous_variant 1.0 pyrazinamide
Rv3236c 3612694 c.421_423delCGTinsGC frameshift_variant&synonymous_variant 1.0 pyrazinamide Uncertain significance
Rv3236c 3612708 c.409T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612712 c.405G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612721 c.396G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612730 c.387C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
Rv3236c 3612736 c.381T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612757 p.Gly120Ala missense_variant 1.0 pyrazinamide
Rv3236c 3612760 c.357C>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612769 c.348T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612772 c.345T>A synonymous_variant 1.0 pyrazinamide
Rv3236c 3612786 c.331T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612787 c.330T>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612796 c.321G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612805 c.312T>C synonymous_variant 1.0 pyrazinamide
lpqB 3623372 c.1539G>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3623379 p.Ala511Gly missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623388 p.Thr508Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623432 c.1479G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623442 p.Ser490Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623450 c.1461G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623480 c.1431C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623484 p.Phe476Tyr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623492 c.1419T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623512 p.Gly467Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623532 p.Gly460Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623561 c.1350T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623576 c.1335T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623587 p.Ala442Pro missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623591 c.1320G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623598 p.Arg438Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623602 p.Ser437Gly missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623614 p.Thr433Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623615 c.1296G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623627 c.1284T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623633 c.1278G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623660 c.1251A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623666 c.1245A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623676 p.Val412Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623682 p.Thr410Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623684 c.1227T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623723 c.1188C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623731 p.Ser394Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623736 p.Ser392Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623739 p.His391Arg missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3623756 c.1155G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624026 c.885G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624032 c.879T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624041 p.Glu290Asp missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624050 c.861C>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624077 c.834G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624089 c.822C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624094 c.817A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624100 c.811T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624101 c.810C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624125 c.786A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624155 c.756G>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624242 c.669A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624245 c.666A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624542 c.369G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624545 c.366T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624551 c.360G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624557 c.354T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624560 c.351G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624563 c.348C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624572 c.339C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624575 c.336T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624594 p.Val106Ala missense_variant 0.94 bedaquiline
rifampicin
lpqB 3624603 p.Lys103Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624605 c.306G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624612 p.Ser100Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624614 c.297A>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624623 c.288C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624629 c.282G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624707 c.204G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624770 c.141T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625258 c.-348G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625528 c.-618G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625717 c.-807C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625978 c.636T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625988 p.Thr209Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625999 c.615A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626095 p.Glu173Asp missense_variant 0.9 bedaquiline
rifampicin
mtrB 3626101 p.Gln171His missense_variant 0.91 bedaquiline
rifampicin
mtrB 3626349 p.Ser89Gly missense_variant 0.77 bedaquiline
rifampicin
mtrB 3626353 c.261C>A synonymous_variant 0.77 bedaquiline
rifampicin
mtrB 3626362 c.252A>G synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626377 p.Asp79Glu missense_variant 0.86 bedaquiline
rifampicin
mtrB 3626383 c.231G>C synonymous_variant 0.87 bedaquiline
rifampicin
mtrB 3626386 c.228G>C synonymous_variant 0.87 bedaquiline
rifampicin
mtrB 3626390 p.Arg75Lys missense_variant 0.87 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 0.93 bedaquiline
rifampicin
mtrB 3626404 c.210C>G synonymous_variant 0.93 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 0.93 bedaquiline
rifampicin
mtrB 3626410 c.204T>G synonymous_variant 0.93 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626437 c.177T>C synonymous_variant 0.92 bedaquiline
rifampicin
mtrB 3626443 c.171T>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626449 c.165G>C synonymous_variant 0.91 bedaquiline
rifampicin
mtrB 3626455 c.159C>G synonymous_variant 0.91 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.92 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627104 c.-491C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627122 c.-509T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627170 c.-557C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627173 c.-560G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627197 c.-584T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627218 c.-605G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627227 c.123T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
alr 3840356 c.1063_1065delCTTinsGC frameshift_variant&missense_variant 1.0 cycloserine
alr 3840360 p.Pro354Gln missense_variant 1.0 cycloserine
alr 3840380 c.1039_1041delATGinsCC frameshift_variant&missense_variant 1.0 cycloserine
alr 3840407 c.1014G>C synonymous_variant 1.0 cycloserine
alr 3840460 p.Ser321Thr missense_variant 1.0 cycloserine
alr 3840476 c.945A>G synonymous_variant 1.0 cycloserine
alr 3840482 c.939T>C synonymous_variant 1.0 cycloserine
alr 3841055 c.366C>G synonymous_variant 1.0 cycloserine
alr 3841064 c.357C>T synonymous_variant 1.0 cycloserine
alr 3841340 c.-8989_80del frameshift_variant 1.0 cycloserine
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 1.0 rifampicin
rpoA 3877685 c.823C>T synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>T synonymous_variant 1.0 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 1.0 rifampicin
rpoA 3877889 p.Ala207Ser missense_variant 1.0 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877950 c.558C>T synonymous_variant 1.0 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>C synonymous_variant 1.0 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 1.0 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 1.0 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878361 c.147G>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878409 c.99C>G synonymous_variant 1.0 rifampicin
rpoA 3878430 c.78G>T synonymous_variant 1.0 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878869 c.-362G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878909 c.-402A>C upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879130 c.-623A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 1.0 rifampicin
clpC1 4038278 c.2427T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 0.9 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 0.9 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038433 c.2272C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 1.0 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038559 p.Ile716Val missense_variant 1.0 pyrazinamide
clpC1 4038560 p.Asp715Glu missense_variant 1.0 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039031 c.1674T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039268 c.1437C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039574 c.1129_1131delGCGinsTC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039621 c.1084C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039679 c.1026C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.91 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.92 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.91 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.9 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.9 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.9 pyrazinamide
clpC1 4040234 c.471C>T synonymous_variant 0.91 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.91 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040336 c.369G>T synonymous_variant 0.91 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.91 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.91 pyrazinamide
clpC1 4040528 c.177G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044755 c.-474G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044758 c.-477C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044809 c.-528C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044812 c.-531A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044818 c.-539_-537delCCGinsGC upstream_gene_variant 1.0 pyrazinamide
panD 4044822 c.-541G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 1.0 pyrazinamide
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin