TB-Profiler

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	0.98

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
fgd1	491512	c.730_732delAACinsGG	frameshift_variant&missense_variant	0.68	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491548	c.766_768delGCTinsCC	frameshift_variant&missense_variant	0.43	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491620	c.838_840delATCinsGG	frameshift_variant&missense_variant	0.77	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
katG	2155764	c.346_348delCACinsGG	frameshift_variant&missense_variant	0.77	isoniazid	Assoc w R	High-level resistance

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
dnaA	371	p.Pro124Leu	missense_variant	1.0	isoniazid	Not assoc w R
dnaA	1220	p.Asn407Thr	missense_variant	0.6	isoniazid
dnaA	1230	c.1230A>G	synonymous_variant	0.67	isoniazid
dnaA	1236	c.1236C>T	synonymous_variant	0.65	isoniazid
dnaA	1237	c.1237_1239delGCGinsAC	frameshift_variant&missense_variant	0.65	isoniazid	Uncertain significance
dnaA	1243	p.Thr415Ala	missense_variant	0.65	isoniazid	Uncertain significance
dnaA	1254	c.1254T>G	synonymous_variant	0.69	isoniazid
dnaA	1266	c.1266A>G	synonymous_variant	0.73	isoniazid
dnaA	1275	p.Asp425Glu	missense_variant	0.73	isoniazid
dnaA	1278	c.1278T>C	synonymous_variant	0.75	isoniazid
dnaA	1281	c.1281C>G	synonymous_variant	0.75	isoniazid
dnaA	1287	c.1287A>G	synonymous_variant	0.8	isoniazid
dnaA	1293	c.1293T>G	synonymous_variant	0.8	isoniazid
dnaA	1314	c.1314A>T	synonymous_variant	0.75	isoniazid
dnaA	1317	c.1317A>G	synonymous_variant	0.75	isoniazid
dnaA	1329	c.1329A>C	synonymous_variant	0.69	isoniazid
dnaA	1332	c.1332A>T	synonymous_variant	0.69	isoniazid
dnaA	1338	c.1338T>C	synonymous_variant	0.69	isoniazid
dnaA	1341	c.1341G>C	synonymous_variant	0.69	isoniazid
dnaA	1347	c.1347C>T	synonymous_variant	0.64	isoniazid
dnaA	1353	c.1353T>C	synonymous_variant	0.57	isoniazid
gyrA	6769	c.-533C>T	upstream_gene_variant	0.64	levofloxacin
gyrA	6769	c.-533C>T	upstream_gene_variant	0.64	moxifloxacin
gyrB	6775	c.1536G>C	synonymous_variant	0.64	levofloxacin	Not assoc w R - Interim
gyrB	6775	c.1536G>C	synonymous_variant	0.64	moxifloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	0.7	levofloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	0.7	moxifloxacin	Not assoc w R - Interim
gyrB	6797	p.Gly520Thr	missense_variant	0.7	levofloxacin
gyrB	6797	p.Gly520Thr	missense_variant	0.7	moxifloxacin
gyrB	6808	c.1569C>T	synonymous_variant	0.83	levofloxacin	Not assoc w R - Interim
gyrB	6808	c.1569C>T	synonymous_variant	0.83	moxifloxacin	Not assoc w R - Interim
gyrB	6811	c.1572C>T	synonymous_variant	0.83	levofloxacin
gyrB	6811	c.1572C>T	synonymous_variant	0.83	moxifloxacin	Not assoc w R - Interim
gyrA	6838	c.-464C>G	upstream_gene_variant	0.85	levofloxacin
gyrA	6838	c.-464C>G	upstream_gene_variant	0.85	moxifloxacin
gyrB	6841	c.1602T>C	synonymous_variant	0.83	levofloxacin	Not assoc w R - Interim
gyrB	6841	c.1602T>C	synonymous_variant	0.83	moxifloxacin	Not assoc w R - Interim
gyrA	6844	c.-458T>G	upstream_gene_variant	0.83	levofloxacin
gyrA	6844	c.-458T>G	upstream_gene_variant	0.83	moxifloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	0.83	levofloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	0.83	moxifloxacin
gyrB	6856	c.1617T>C	synonymous_variant	0.82	levofloxacin	Not assoc w R - Interim
gyrB	6856	c.1617T>C	synonymous_variant	0.82	moxifloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	0.82	levofloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	0.82	moxifloxacin	Not assoc w R - Interim
gyrA	7362	p.Glu21Gln	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7362	p.Glu21Gln	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7391	c.90C>T	synonymous_variant	0.63	levofloxacin	Not assoc w R - Interim
gyrA	7391	c.90C>T	synonymous_variant	0.63	moxifloxacin	Not assoc w R - Interim
gyrA	7394	c.93T>C	synonymous_variant	0.63	levofloxacin	Not assoc w R - Interim
gyrA	7394	c.93T>C	synonymous_variant	0.63	moxifloxacin
gyrA	7397	c.96G>C	synonymous_variant	0.65	levofloxacin
gyrA	7397	c.96G>C	synonymous_variant	0.65	moxifloxacin
gyrA	7406	c.105G>C	synonymous_variant	0.76	levofloxacin
gyrA	7406	c.105G>C	synonymous_variant	0.76	moxifloxacin
gyrA	7412	c.111C>G	synonymous_variant	0.76	levofloxacin
gyrA	7412	c.111C>G	synonymous_variant	0.76	moxifloxacin
gyrA	7418	c.117C>T	synonymous_variant	0.79	levofloxacin
gyrA	7418	c.117C>T	synonymous_variant	0.79	moxifloxacin
gyrA	7433	c.132G>A	synonymous_variant	0.81	levofloxacin
gyrA	7433	c.132G>A	synonymous_variant	0.81	moxifloxacin
gyrA	7442	c.141G>C	synonymous_variant	0.79	levofloxacin
gyrA	7442	c.141G>C	synonymous_variant	0.79	moxifloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.83	levofloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.83	moxifloxacin
gyrA	7463	c.162G>C	synonymous_variant	0.84	levofloxacin
gyrA	7463	c.162G>C	synonymous_variant	0.84	moxifloxacin
gyrA	7472	c.171T>C	synonymous_variant	0.82	levofloxacin	Not assoc w R - Interim
gyrA	7472	c.171T>C	synonymous_variant	0.82	moxifloxacin
gyrA	7475	c.174A>G	synonymous_variant	0.79	levofloxacin	Not assoc w R - Interim
gyrA	7475	c.174A>G	synonymous_variant	0.79	moxifloxacin	Not assoc w R - Interim
gyrA	7480	p.Phe60Tyr	missense_variant	0.81	levofloxacin
gyrA	7480	p.Phe60Tyr	missense_variant	0.81	moxifloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.82	levofloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.82	moxifloxacin
gyrA	7499	c.198G>C	synonymous_variant	0.83	levofloxacin
gyrA	7499	c.198G>C	synonymous_variant	0.83	moxifloxacin
gyrA	7526	c.225G>C	synonymous_variant	0.81	levofloxacin	Not assoc w R - Interim
gyrA	7526	c.225G>C	synonymous_variant	0.81	moxifloxacin	Not assoc w R - Interim
gyrA	7532	c.231T>G	synonymous_variant	0.79	levofloxacin	Not assoc w R - Interim
gyrA	7532	c.231T>G	synonymous_variant	0.79	moxifloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.76	levofloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.76	moxifloxacin	Not assoc w R - Interim
gyrA	7547	c.246C>T	synonymous_variant	0.75	levofloxacin	Not assoc w R - Interim
gyrA	7547	c.246C>T	synonymous_variant	0.75	moxifloxacin	Not assoc w R - Interim
gyrA	7565	c.264C>T	synonymous_variant	0.73	levofloxacin	Not assoc w R - Interim
gyrA	7565	c.264C>T	synonymous_variant	0.73	moxifloxacin	Not assoc w R - Interim
gyrA	7569	p.Ala90Ser	missense_variant	0.71	levofloxacin
gyrA	7569	p.Ala90Ser	missense_variant	0.71	moxifloxacin
gyrA	7585	p.Ser95Thr	missense_variant	0.68	levofloxacin	Not assoc w R
gyrA	7585	p.Ser95Thr	missense_variant	0.68	moxifloxacin	Not assoc w R
gyrA	7592	c.291G>C	synonymous_variant	0.72	levofloxacin	Not assoc w R - Interim
gyrA	7592	c.291G>C	synonymous_variant	0.72	moxifloxacin	Not assoc w R - Interim
gyrA	7595	c.294C>G	synonymous_variant	0.71	levofloxacin
gyrA	7595	c.294C>G	synonymous_variant	0.71	moxifloxacin
gyrA	7601	c.300C>T	synonymous_variant	0.67	levofloxacin
gyrA	7601	c.300C>T	synonymous_variant	0.67	moxifloxacin
gyrA	7607	c.306C>G	synonymous_variant	0.65	levofloxacin	Not assoc w R - Interim
gyrA	7607	c.306C>G	synonymous_variant	0.65	moxifloxacin	Not assoc w R - Interim
gyrA	7613	c.312G>A	synonymous_variant	0.72	levofloxacin	Not assoc w R - Interim
gyrA	7613	c.312G>A	synonymous_variant	0.72	moxifloxacin	Not assoc w R - Interim
gyrA	7622	c.321C>T	synonymous_variant	0.67	levofloxacin
gyrA	7622	c.321C>T	synonymous_variant	0.67	moxifloxacin
gyrA	7631	c.330G>C	synonymous_variant	0.56	levofloxacin
gyrA	7631	c.330G>C	synonymous_variant	0.56	moxifloxacin
gyrA	7637	c.336C>T	synonymous_variant	0.56	levofloxacin
gyrA	7637	c.336C>T	synonymous_variant	0.56	moxifloxacin
gyrA	7652	c.351C>T	synonymous_variant	0.47	levofloxacin
gyrA	7652	c.351C>T	synonymous_variant	0.47	moxifloxacin
gyrA	7694	c.393A>G	synonymous_variant	0.47	levofloxacin
gyrA	7694	c.393A>G	synonymous_variant	0.47	moxifloxacin
gyrA	7697	c.396C>G	synonymous_variant	0.47	levofloxacin
gyrA	7697	c.396C>G	synonymous_variant	0.47	moxifloxacin
gyrA	7706	c.405C>T	synonymous_variant	0.44	levofloxacin
gyrA	7706	c.405C>T	synonymous_variant	0.44	moxifloxacin
gyrA	7709	c.408G>C	synonymous_variant	0.5	levofloxacin
gyrA	7709	c.408G>C	synonymous_variant	0.5	moxifloxacin
gyrA	7710	c.409T>C	synonymous_variant	0.5	levofloxacin
gyrA	7710	c.409T>C	synonymous_variant	0.5	moxifloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.68	levofloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.68	moxifloxacin
gyrA	7763	c.462T>G	synonymous_variant	0.74	levofloxacin
gyrA	7763	c.462T>G	synonymous_variant	0.74	moxifloxacin
gyrA	7775	c.474C>T	synonymous_variant	0.76	levofloxacin	Not assoc w R - Interim
gyrA	7775	c.474C>T	synonymous_variant	0.76	moxifloxacin	Not assoc w R - Interim
gyrA	7784	c.483A>G	synonymous_variant	0.81	levofloxacin
gyrA	7784	c.483A>G	synonymous_variant	0.81	moxifloxacin
gyrA	7790	c.489G>C	synonymous_variant	0.81	levofloxacin
gyrA	7790	c.489G>C	synonymous_variant	0.81	moxifloxacin
gyrA	7796	c.495G>T	synonymous_variant	0.81	levofloxacin
gyrA	7796	c.495G>T	synonymous_variant	0.81	moxifloxacin
gyrA	7799	c.498A>G	synonymous_variant	0.78	levofloxacin	Not assoc w R - Interim
gyrA	7799	c.498A>G	synonymous_variant	0.78	moxifloxacin	Not assoc w R - Interim
gyrA	7802	c.501C>G	synonymous_variant	0.78	levofloxacin
gyrA	7802	c.501C>G	synonymous_variant	0.78	moxifloxacin
gyrA	7832	c.531G>T	synonymous_variant	0.87	levofloxacin
gyrA	7832	c.531G>T	synonymous_variant	0.87	moxifloxacin
gyrA	7835	c.534A>G	synonymous_variant	0.87	levofloxacin	Not assoc w R - Interim
gyrA	7835	c.534A>G	synonymous_variant	0.87	moxifloxacin	Not assoc w R - Interim
gyrA	7841	c.540C>T	synonymous_variant	0.86	levofloxacin	Not assoc w R - Interim
gyrA	7841	c.540C>T	synonymous_variant	0.86	moxifloxacin	Not assoc w R - Interim
gyrA	7847	c.546G>C	synonymous_variant	0.83	levofloxacin
gyrA	7847	c.546G>C	synonymous_variant	0.83	moxifloxacin
gyrA	7859	c.558A>C	synonymous_variant	0.84	levofloxacin
gyrA	7859	c.558A>C	synonymous_variant	0.84	moxifloxacin
gyrA	7865	c.564T>C	synonymous_variant	0.74	levofloxacin
gyrA	7865	c.564T>C	synonymous_variant	0.74	moxifloxacin
gyrA	7886	c.585T>G	synonymous_variant	0.62	levofloxacin
gyrA	7886	c.585T>G	synonymous_variant	0.62	moxifloxacin
gyrA	8168	c.867A>G	synonymous_variant	0.69	levofloxacin
gyrA	8168	c.867A>G	synonymous_variant	0.69	moxifloxacin
gyrA	8174	c.873C>G	synonymous_variant	0.69	levofloxacin
gyrA	8174	c.873C>G	synonymous_variant	0.69	moxifloxacin
gyrA	8177	c.876A>C	synonymous_variant	0.71	levofloxacin
gyrA	8177	c.876A>C	synonymous_variant	0.71	moxifloxacin
gyrA	8191	p.Ala297Gly	missense_variant	0.63	levofloxacin	Uncertain significance
gyrA	8191	p.Ala297Gly	missense_variant	0.63	moxifloxacin	Uncertain significance
gyrA	8198	c.897T>C	synonymous_variant	0.63	levofloxacin	Not assoc w R - Interim
gyrA	8198	c.897T>C	synonymous_variant	0.63	moxifloxacin	Not assoc w R - Interim
gyrA	8207	c.906T>C	synonymous_variant	0.63	levofloxacin
gyrA	8207	c.906T>C	synonymous_variant	0.63	moxifloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.6	levofloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.6	moxifloxacin
gyrA	8219	c.918T>C	synonymous_variant	0.6	levofloxacin	Not assoc w R - Interim
gyrA	8219	c.918T>C	synonymous_variant	0.6	moxifloxacin	Not assoc w R - Interim
gyrA	8222	c.921C>T	synonymous_variant	0.6	levofloxacin
gyrA	8222	c.921C>T	synonymous_variant	0.6	moxifloxacin
gyrA	8225	c.924T>C	synonymous_variant	0.6	levofloxacin
gyrA	8225	c.924T>C	synonymous_variant	0.6	moxifloxacin
gyrA	8235	c.934_936delTTAinsCG	frameshift_variant&missense_variant	0.58	levofloxacin
gyrA	8235	c.934_936delTTAinsCG	frameshift_variant&missense_variant	0.58	moxifloxacin
gyrA	8240	c.939C>A	synonymous_variant	0.56	levofloxacin
gyrA	8240	c.939C>A	synonymous_variant	0.56	moxifloxacin
gyrA	8243	c.942C>T	synonymous_variant	0.53	levofloxacin
gyrA	8243	c.942C>T	synonymous_variant	0.53	moxifloxacin
gyrA	8246	c.945C>G	synonymous_variant	0.56	levofloxacin	Not assoc w R - Interim
gyrA	8246	c.945C>G	synonymous_variant	0.56	moxifloxacin	Not assoc w R - Interim
gyrA	8247	c.946_948delATCinsGG	frameshift_variant&missense_variant	0.56	levofloxacin
gyrA	8247	c.946_948delATCinsGG	frameshift_variant&missense_variant	0.56	moxifloxacin
gyrA	8253	p.Ile318Leu	missense_variant	0.56	levofloxacin
gyrA	8253	p.Ile318Leu	missense_variant	0.56	moxifloxacin
gyrA	8267	c.966G>C	synonymous_variant	0.56	levofloxacin	Not assoc w R - Interim
gyrA	8267	c.966G>C	synonymous_variant	0.56	moxifloxacin	Not assoc w R - Interim
gyrA	8354	c.1053G>C	synonymous_variant	0.5	levofloxacin	Not assoc w R - Interim
gyrA	8354	c.1053G>C	synonymous_variant	0.5	moxifloxacin	Not assoc w R - Interim
gyrA	8366	c.1065G>C	synonymous_variant	0.6	levofloxacin
gyrA	8366	c.1065G>C	synonymous_variant	0.6	moxifloxacin
gyrA	8372	c.1071G>T	synonymous_variant	0.6	levofloxacin
gyrA	8372	c.1071G>T	synonymous_variant	0.6	moxifloxacin
gyrA	8390	c.1089C>G	synonymous_variant	0.67	levofloxacin
gyrA	8390	c.1089C>G	synonymous_variant	0.67	moxifloxacin
gyrA	8391	p.Tyr364Leu	missense_variant	0.67	levofloxacin
gyrA	8391	p.Tyr364Leu	missense_variant	0.67	moxifloxacin
gyrA	8399	c.1098T>G	synonymous_variant	0.71	levofloxacin
gyrA	8399	c.1098T>G	synonymous_variant	0.71	moxifloxacin
gyrA	8408	c.1107A>G	synonymous_variant	0.67	levofloxacin
gyrA	8408	c.1107A>G	synonymous_variant	0.67	moxifloxacin
gyrA	8414	c.1113C>T	synonymous_variant	0.67	levofloxacin	Not assoc w R - Interim
gyrA	8414	c.1113C>T	synonymous_variant	0.67	moxifloxacin	Not assoc w R - Interim
gyrA	8420	c.1119T>C	synonymous_variant	0.68	levofloxacin
gyrA	8420	c.1119T>C	synonymous_variant	0.68	moxifloxacin
gyrA	8433	p.Thr378Arg	missense_variant	0.67	levofloxacin
gyrA	8433	p.Thr378Arg	missense_variant	0.67	moxifloxacin
gyrA	8442	c.1141C>T	synonymous_variant	0.68	levofloxacin
gyrA	8442	c.1141C>T	synonymous_variant	0.68	moxifloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.71	levofloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.71	moxifloxacin
gyrA	8456	c.1155C>T	synonymous_variant	0.67	levofloxacin
gyrA	8456	c.1155C>T	synonymous_variant	0.67	moxifloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.71	levofloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.71	moxifloxacin
gyrA	8462	c.1161A>G	synonymous_variant	0.74	levofloxacin
gyrA	8462	c.1161A>G	synonymous_variant	0.74	moxifloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.8	levofloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.8	moxifloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.74	levofloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.74	moxifloxacin
gyrA	8486	c.1185T>C	synonymous_variant	0.77	levofloxacin	Not assoc w R - Interim
gyrA	8486	c.1185T>C	synonymous_variant	0.77	moxifloxacin	Not assoc w R - Interim
gyrA	8504	c.1203G>C	synonymous_variant	0.67	levofloxacin
gyrA	8504	c.1203G>C	synonymous_variant	0.67	moxifloxacin
gyrA	8510	c.1209G>A	synonymous_variant	0.67	levofloxacin	Not assoc w R - Interim
gyrA	8510	c.1209G>A	synonymous_variant	0.67	moxifloxacin	Not assoc w R - Interim
gyrA	8513	c.1212C>G	synonymous_variant	0.67	levofloxacin	Not assoc w R - Interim
gyrA	8513	c.1212C>G	synonymous_variant	0.67	moxifloxacin	Not assoc w R - Interim
gyrA	8516	c.1215T>C	synonymous_variant	0.67	levofloxacin
gyrA	8516	c.1215T>C	synonymous_variant	0.67	moxifloxacin
gyrA	8519	c.1218A>G	synonymous_variant	0.67	levofloxacin	Not assoc w R - Interim
gyrA	8519	c.1218A>G	synonymous_variant	0.67	moxifloxacin	Not assoc w R - Interim
gyrA	8520	c.1219C>T	synonymous_variant	0.67	levofloxacin
gyrA	8520	c.1219C>T	synonymous_variant	0.67	moxifloxacin
gyrA	8535	p.Glu412Gln	missense_variant	0.62	levofloxacin
gyrA	8535	p.Glu412Gln	missense_variant	0.62	moxifloxacin
gyrA	8546	p.Asp415Glu	missense_variant	0.65	levofloxacin
gyrA	8546	p.Asp415Glu	missense_variant	0.65	moxifloxacin
gyrA	8561	c.1260A>C	synonymous_variant	0.73	levofloxacin	Not assoc w R - Interim
gyrA	8561	c.1260A>C	synonymous_variant	0.73	moxifloxacin	Not assoc w R - Interim
gyrA	8571	c.1270C>T	synonymous_variant	0.75	levofloxacin
gyrA	8571	c.1270C>T	synonymous_variant	0.75	moxifloxacin
gyrA	8603	c.1302A>C	synonymous_variant	0.81	levofloxacin
gyrA	8603	c.1302A>C	synonymous_variant	0.81	moxifloxacin
gyrA	8624	c.1323G>C	synonymous_variant	0.67	levofloxacin
gyrA	8624	c.1323G>C	synonymous_variant	0.67	moxifloxacin
gyrA	8627	c.1326C>G	synonymous_variant	0.67	levofloxacin
gyrA	8627	c.1326C>G	synonymous_variant	0.67	moxifloxacin
gyrA	8628	c.1327C>T	synonymous_variant	0.67	levofloxacin
gyrA	8628	c.1327C>T	synonymous_variant	0.67	moxifloxacin
gyrA	8633	c.1332C>T	synonymous_variant	0.71	levofloxacin
gyrA	8633	c.1332C>T	synonymous_variant	0.71	moxifloxacin
gyrA	8636	c.1335A>C	synonymous_variant	0.71	levofloxacin	Not assoc w R - Interim
gyrA	8636	c.1335A>C	synonymous_variant	0.71	moxifloxacin	Not assoc w R - Interim
gyrA	8645	c.1344C>A	synonymous_variant	0.79	levofloxacin
gyrA	8645	c.1344C>A	synonymous_variant	0.79	moxifloxacin
gyrA	8649	p.Arg450Lys	missense_variant	0.79	levofloxacin
gyrA	8649	p.Arg450Lys	missense_variant	0.79	moxifloxacin
gyrA	8655	p.Ile452Val	missense_variant	0.73	levofloxacin
gyrA	8655	p.Ile452Val	missense_variant	0.73	moxifloxacin
gyrA	8663	c.1362C>T	synonymous_variant	0.73	levofloxacin
gyrA	8663	c.1362C>T	synonymous_variant	0.73	moxifloxacin
gyrA	8672	c.1371A>G	synonymous_variant	0.65	levofloxacin	Not assoc w R - Interim
gyrA	8672	c.1371A>G	synonymous_variant	0.65	moxifloxacin	Not assoc w R - Interim
gyrA	8678	c.1377G>A	synonymous_variant	0.65	levofloxacin
gyrA	8678	c.1377G>A	synonymous_variant	0.65	moxifloxacin
gyrA	8696	c.1395G>C	synonymous_variant	0.67	levofloxacin
gyrA	8696	c.1395G>C	synonymous_variant	0.67	moxifloxacin
gyrA	8699	c.1398A>G	synonymous_variant	0.62	levofloxacin
gyrA	8699	c.1398A>G	synonymous_variant	0.62	moxifloxacin
gyrA	8705	c.1404C>T	synonymous_variant	0.58	levofloxacin	Not assoc w R - Interim
gyrA	8705	c.1404C>T	synonymous_variant	0.58	moxifloxacin	Not assoc w R - Interim
gyrA	8998	p.Leu566Trp	missense_variant	0.6	levofloxacin	Uncertain significance
gyrA	8998	p.Leu566Trp	missense_variant	0.6	moxifloxacin	Uncertain significance
gyrA	9017	c.1716C>G	synonymous_variant	0.6	levofloxacin	Not assoc w R - Interim
gyrA	9017	c.1716C>G	synonymous_variant	0.6	moxifloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	0.64	levofloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	0.64	moxifloxacin	Not assoc w R - Interim
gyrA	9029	c.1728T>G	synonymous_variant	0.62	levofloxacin
gyrA	9029	c.1728T>G	synonymous_variant	0.62	moxifloxacin
gyrA	9032	c.1731T>C	synonymous_variant	0.62	levofloxacin
gyrA	9032	c.1731T>C	synonymous_variant	0.62	moxifloxacin
gyrA	9038	c.1737C>A	synonymous_variant	0.67	levofloxacin
gyrA	9038	c.1737C>A	synonymous_variant	0.67	moxifloxacin
fgd1	491091	c.309T>C	synonymous_variant	0.55	clofazimine
					pretomanid
					delamanid
fgd1	491115	c.333G>C	synonymous_variant	0.68	clofazimine
					pretomanid
					delamanid
fgd1	491121	c.339A>G	synonymous_variant	0.68	clofazimine
					pretomanid
					delamanid
fgd1	491166	c.384G>C	synonymous_variant	0.55	clofazimine
					pretomanid
					delamanid
fgd1	491490	c.708C>T	synonymous_variant	0.65	clofazimine
					pretomanid
					delamanid
fgd1	491499	c.717G>C	synonymous_variant	0.67	clofazimine
					pretomanid
					delamanid
fgd1	491500	p.Glu240Lys	missense_variant	0.67	clofazimine
					pretomanid
					delamanid
fgd1	491508	c.726A>C	synonymous_variant	0.65	clofazimine
					pretomanid
					delamanid
fgd1	491523	c.741G>C	synonymous_variant	0.69	clofazimine
					pretomanid
					delamanid
fgd1	491526	c.744T>C	synonymous_variant	0.69	clofazimine
					pretomanid
					delamanid
fgd1	491542	c.760T>C	synonymous_variant	0.67	clofazimine
					pretomanid
					delamanid
fgd1	491547	c.765A>T	synonymous_variant	0.57	clofazimine
					pretomanid
					delamanid
fgd1	491563	c.781_783delAGCinsTCG	synonymous_variant	0.72	clofazimine
					pretomanid
					delamanid
fgd1	491595	c.813C>T	synonymous_variant	0.84	clofazimine
					pretomanid
					delamanid
fgd1	491610	c.828A>G	synonymous_variant	0.81	clofazimine
					pretomanid
					delamanid
fgd1	491616	c.834A>G	synonymous_variant	0.79	clofazimine
					pretomanid
					delamanid
fgd1	491649	c.867C>T	synonymous_variant	0.68	clofazimine
					pretomanid
					delamanid
fgd1	491655	c.873C>T	synonymous_variant	0.62	clofazimine
					pretomanid
					delamanid
fgd1	491658	c.876A>G	synonymous_variant	0.65	clofazimine
					pretomanid
					delamanid
fgd1	491661	c.879C>G	synonymous_variant	0.65	clofazimine
					pretomanid
					delamanid
fgd1	491667	c.885A>G	synonymous_variant	0.65	clofazimine
					pretomanid
					delamanid
fgd1	491673	c.891A>G	synonymous_variant	0.6	clofazimine
					pretomanid
					delamanid
fgd1	491676	c.894T>C	synonymous_variant	0.6	clofazimine
					pretomanid
					delamanid
fgd1	491679	c.897A>G	synonymous_variant	0.6	clofazimine
					pretomanid
					delamanid
fgd1	491697	c.915G>C	synonymous_variant	0.63	clofazimine
					pretomanid
					delamanid
mshA	575689	c.342G>C	synonymous_variant	0.6	ethionamide
mshA	575689	c.342G>C	synonymous_variant	0.6	isoniazid
mshA	575692	c.345G>A	synonymous_variant	0.62	ethionamide
mshA	575692	c.345G>A	synonymous_variant	0.62	isoniazid
mshA	575704	c.357T>C	synonymous_variant	0.65	ethionamide
mshA	575704	c.357T>C	synonymous_variant	0.65	isoniazid
mshA	575705	c.358T>C	synonymous_variant	0.65	ethionamide
mshA	575705	c.358T>C	synonymous_variant	0.65	isoniazid
mshA	575725	c.378C>G	synonymous_variant	0.69	ethionamide
mshA	575725	c.378C>G	synonymous_variant	0.69	isoniazid
mshA	575734	c.387T>G	synonymous_variant	0.69	ethionamide
mshA	575734	c.387T>G	synonymous_variant	0.69	isoniazid
mshA	575744	p.Ala133Thr	missense_variant	0.67	ethionamide
mshA	575744	p.Ala133Thr	missense_variant	0.67	isoniazid	Uncertain significance
mshA	575749	c.402C>A	synonymous_variant	0.69	ethionamide
mshA	575749	c.402C>A	synonymous_variant	0.69	isoniazid
mshA	575764	c.417C>G	synonymous_variant	0.71	ethionamide
mshA	575764	c.417C>G	synonymous_variant	0.71	isoniazid
mshA	575771	p.Val142Thr	missense_variant	0.73	ethionamide
mshA	575771	p.Val142Thr	missense_variant	0.73	isoniazid
mshA	575776	c.429C>T	synonymous_variant	0.73	ethionamide
mshA	575776	c.429C>T	synonymous_variant	0.73	isoniazid
mshA	575782	c.435G>C	synonymous_variant	0.74	ethionamide
mshA	575782	c.435G>C	synonymous_variant	0.74	isoniazid
mshA	575785	c.438T>C	synonymous_variant	0.74	ethionamide
mshA	575785	c.438T>C	synonymous_variant	0.74	isoniazid
mshA	575795	p.Ile150Val	missense_variant	0.74	ethionamide
mshA	575795	p.Ile150Val	missense_variant	0.74	isoniazid
mshA	575800	c.453G>C	synonymous_variant	0.74	ethionamide
mshA	575800	c.453G>C	synonymous_variant	0.74	isoniazid
mshA	575803	c.456C>T	synonymous_variant	0.74	ethionamide
mshA	575803	c.456C>T	synonymous_variant	0.74	isoniazid	Not assoc w R - Interim
mshA	575821	c.474G>C	synonymous_variant	0.73	ethionamide
mshA	575821	c.474G>C	synonymous_variant	0.73	isoniazid
mshA	575842	c.495G>C	synonymous_variant	0.73	ethionamide
mshA	575842	c.495G>C	synonymous_variant	0.73	isoniazid
mshA	575864	c.517T>C	synonymous_variant	0.73	ethionamide
mshA	575864	c.517T>C	synonymous_variant	0.73	isoniazid
mshA	575893	c.546C>G	synonymous_variant	0.76	ethionamide
mshA	575893	c.546C>G	synonymous_variant	0.76	isoniazid
mshA	575905	c.558G>A	synonymous_variant	0.6	ethionamide
mshA	575905	c.558G>A	synonymous_variant	0.6	isoniazid
mshA	575906	c.559_561delGCAinsTC	frameshift_variant&missense_variant	0.6	ethionamide	Uncertain significance
mshA	575906	c.559_561delGCAinsTC	frameshift_variant&missense_variant	0.6	isoniazid	Uncertain significance
mshA	575916	p.Asp190Ala	missense_variant	0.64	ethionamide
mshA	575916	p.Asp190Ala	missense_variant	0.64	isoniazid
mshA	575920	c.573C>T	synonymous_variant	0.64	ethionamide	Not assoc w R - Interim
mshA	575920	c.573C>T	synonymous_variant	0.64	isoniazid	Not assoc w R - Interim
mshA	575925	p.Gly193Ala	missense_variant	0.64	ethionamide
mshA	575925	p.Gly193Ala	missense_variant	0.64	isoniazid
mshA	575929	c.582C>G	synonymous_variant	0.64	ethionamide
mshA	575929	c.582C>G	synonymous_variant	0.64	isoniazid
mshA	575935	c.588G>A	synonymous_variant	0.64	ethionamide
mshA	575935	c.588G>A	synonymous_variant	0.64	isoniazid
mshA	575939	c.592C>T	synonymous_variant	0.64	ethionamide
mshA	575939	c.592C>T	synonymous_variant	0.64	isoniazid
mshA	575944	c.597T>C	synonymous_variant	0.64	ethionamide
mshA	575944	c.597T>C	synonymous_variant	0.64	isoniazid
mshA	575945	p.Thr200Ala	missense_variant	0.64	ethionamide
mshA	575945	p.Thr200Ala	missense_variant	0.64	isoniazid
mshA	575950	c.603C>G	synonymous_variant	0.64	ethionamide
mshA	575950	c.603C>G	synonymous_variant	0.64	isoniazid
mshA	575965	c.618C>G	synonymous_variant	0.64	ethionamide
mshA	575965	c.618C>G	synonymous_variant	0.64	isoniazid	Not assoc w R - Interim
ccsA	620340	c.450C>G	synonymous_variant	0.56	capreomycin
					amikacin
					kanamycin
ccsA	620346	c.456C>G	synonymous_variant	0.56	capreomycin
					amikacin
					kanamycin
ccsA	620358	c.468C>G	synonymous_variant	0.56	capreomycin
					amikacin
					kanamycin
ccsA	620362	p.Ala158Ser	missense_variant	0.56	capreomycin
					amikacin
					kanamycin
ccsA	620367	c.477T>C	synonymous_variant	0.56	capreomycin
					amikacin
					kanamycin
ccsA	620385	c.495G>C	synonymous_variant	0.6	capreomycin
					amikacin
					kanamycin
ccsA	620388	c.498A>G	synonymous_variant	0.6	capreomycin
					amikacin
					kanamycin
ccsA	620397	c.507C>G	synonymous_variant	0.56	capreomycin
					amikacin
					kanamycin
ccsA	620412	c.522T>C	synonymous_variant	0.64	capreomycin
					amikacin
					kanamycin
ccsA	620415	c.525T>C	synonymous_variant	0.64	capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
ccsA	620421	c.531G>C	synonymous_variant	0.69	capreomycin
					amikacin
					kanamycin
ccsA	620427	c.537C>G	synonymous_variant	0.75	capreomycin
					amikacin
					kanamycin
ccsA	620436	c.546T>C	synonymous_variant	0.73	capreomycin
					amikacin
					kanamycin
ccsA	620439	c.549T>C	synonymous_variant	0.73	capreomycin
					amikacin
					kanamycin
ccsA	620442	c.552G>C	synonymous_variant	0.8	capreomycin
					amikacin
					kanamycin
ccsA	620445	c.555A>G	synonymous_variant	0.8	capreomycin
					amikacin
					kanamycin
ccsA	620619	c.729G>C	synonymous_variant	0.79	capreomycin
					amikacin
					kanamycin
ccsA	620631	c.741T>C	synonymous_variant	0.83	capreomycin
					amikacin
					kanamycin
ccsA	620649	c.759A>G	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620652	c.762C>G	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620661	c.771C>G	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620670	c.780C>T	synonymous_variant	0.89	capreomycin
					amikacin
					kanamycin
ccsA	620694	c.804C>G	synonymous_variant	0.9	capreomycin
					amikacin
					kanamycin
ccsA	620698	p.Val270Ile	missense_variant	0.9	capreomycin
					amikacin
					kanamycin
ccsA	620715	c.825C>T	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620730	c.840C>T	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620733	c.843G>C	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620736	c.846G>A	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620739	c.849A>G	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620742	c.852G>C	synonymous_variant	0.86	capreomycin
					amikacin
					kanamycin
ccsA	620757	c.867C>T	synonymous_variant	0.89	capreomycin
					amikacin
					kanamycin
ccsA	620764	c.874_876delGCCinsTG	frameshift_variant&missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620778	c.888T>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620781	c.891C>T	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620783	p.Ala298Val	missense_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620793	c.903G>C	synonymous_variant	0.92	capreomycin
					amikacin
					kanamycin
Rv0565c	657636	c.-167_-166delAGinsTC	upstream_gene_variant	0.69	ethionamide
Rv0565c	657639	c.-169C>G	upstream_gene_variant	0.69	ethionamide
Rv0565c	657649	c.-179G>A	upstream_gene_variant	0.64	ethionamide
Rv0565c	657670	c.-200A>G	upstream_gene_variant	0.64	ethionamide
Rv0565c	657671	c.-201A>G	upstream_gene_variant	0.64	ethionamide
Rv0565c	657678	c.-209_-208delAAinsGG	upstream_gene_variant	0.64	ethionamide
Rv0565c	657689	c.-220_-219delCAinsAG	upstream_gene_variant	0.64	ethionamide
Rv0565c	657703	c.-233C>A	upstream_gene_variant	0.57	ethionamide
Rv0565c	657722	c.-254_-252delAACinsCG	upstream_gene_variant	0.67	ethionamide
Rv0565c	657734	c.-264T>C	upstream_gene_variant	0.62	ethionamide
nusG	734403	c.150C>T	synonymous_variant	0.8	rifampicin
nusG	734407	c.154_156delGTTinsAC	frameshift_variant&missense_variant	0.8	rifampicin
nusG	734421	c.168A>C	synonymous_variant	0.87	rifampicin
nusG	734424	c.171G>C	synonymous_variant	0.88	rifampicin
nusG	734439	c.186C>G	synonymous_variant	0.9	rifampicin
nusG	734451	c.198G>C	synonymous_variant	0.9	rifampicin
nusG	734454	c.201A>G	synonymous_variant	0.83	rifampicin
nusG	734460	c.207G>C	synonymous_variant	0.8	rifampicin
nusG	734472	c.219T>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
nusG	734475	c.222T>C	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
nusG	734478	c.225C>G	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
nusG	734499	c.246G>C	synonymous_variant	0.77	rifampicin
nusG	734532	c.279A>G	synonymous_variant	0.72	rifampicin	Not assoc w R - Interim
nusG	734541	c.288A>G	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
nusG	734544	c.291C>T	synonymous_variant	0.67	rifampicin
nusG	734559	c.306T>C	synonymous_variant	0.65	rifampicin
nusG	734571	c.318C>G	synonymous_variant	0.53	rifampicin
nusG	734580	c.327T>C	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoB	760181	c.375T>C	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	760184	c.378A>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	760196	c.390C>G	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
rpoB	760235	c.429T>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoB	760244	c.438G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoB	760283	c.477G>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	760298	c.492G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760310	c.504G>C	synonymous_variant	0.93	rifampicin
rpoB	760316	c.510C>G	synonymous_variant	0.96	rifampicin
rpoB	760325	c.519G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760331	c.525G>C	synonymous_variant	0.96	rifampicin
rpoB	760334	c.528G>T	synonymous_variant	0.96	rifampicin
rpoB	760340	c.534G>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760357	p.Thr184Ser	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	760361	c.555T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760376	p.Asp190Glu	missense_variant	0.96	rifampicin	Uncertain significance
rpoB	760406	c.600G>C	synonymous_variant	0.92	rifampicin
rpoB	760407	p.Ser201Gly	missense_variant	0.92	rifampicin	Uncertain significance
rpoB	760415	c.609C>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760424	c.618C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760430	c.624T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	760433	c.627C>T	synonymous_variant	0.9	rifampicin
rpoB	760457	c.651C>T	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoB	760463	c.657C>T	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	760475	c.669A>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	760478	c.672C>T	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	760481	c.675G>T	synonymous_variant	0.82	rifampicin
rpoB	760484	c.678A>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	760502	c.696C>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	760522	p.Ser239Asn	missense_variant	0.76	rifampicin	Uncertain significance
rpoB	760532	c.726T>C	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoB	760533	p.Val243Thr	missense_variant	0.71	rifampicin
rpoB	760541	c.735G>C	synonymous_variant	0.72	rifampicin	Not assoc w R - Interim
rpoB	760547	c.741G>C	synonymous_variant	0.72	rifampicin	Not assoc w R - Interim
rpoB	760561	c.757_758delCG	frameshift_variant	0.71	rifampicin
rpoB	760567	p.Ser254Trp	missense_variant	0.68	rifampicin
rpoB	760568	c.762_763insGC	frameshift_variant	0.68	rifampicin
rpoB	760571	c.765G>C	synonymous_variant	0.7	rifampicin
rpoB	760585	p.Asn260Ser	missense_variant	0.69	rifampicin
rpoB	760591	p.Val262Ala	missense_variant	0.71	rifampicin
rpoB	760595	c.789C>T	synonymous_variant	0.71	rifampicin
rpoB	760596	p.Thr264Pro	missense_variant	0.71	rifampicin
rpoB	760611	c.805T>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	760646	c.840C>G	synonymous_variant	0.7	rifampicin	Not assoc w R - Interim
rpoB	760655	c.849A>G	synonymous_variant	0.7	rifampicin	Not assoc w R - Interim
rpoB	760661	c.855A>C	synonymous_variant	0.72	rifampicin	Not assoc w R - Interim
rpoB	760670	c.864G>C	synonymous_variant	0.79	rifampicin
rpoB	760674	c.868T>C	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	760679	c.873A>G	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	760683	c.877T>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	760703	c.897C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoB	760721	c.915C>G	synonymous_variant	0.75	rifampicin
rpoB	760724	c.918T>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	760730	c.924T>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	760748	c.942C>G	synonymous_variant	0.71	rifampicin
rpoB	760751	c.945G>C	synonymous_variant	0.68	rifampicin
rpoB	760755	c.949_951delCATinsAC	frameshift_variant&missense_variant	0.71	rifampicin
rpoB	760759	p.Val318Ala	missense_variant	0.71	rifampicin
rpoB	760764	p.Glu320Gln	missense_variant	0.74	rifampicin
rpoB	760769	c.963C>G	synonymous_variant	0.74	rifampicin
rpoB	760784	c.978G>T	synonymous_variant	0.75	rifampicin
rpoB	760793	c.987A>G	synonymous_variant	0.71	rifampicin
rpoB	760805	c.999G>C	synonymous_variant	0.75	rifampicin
rpoB	760817	c.1011A>G	synonymous_variant	0.74	rifampicin
rpoB	760820	c.1014T>C	synonymous_variant	0.74	rifampicin
rpoB	760826	c.1020C>G	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoB	760830	c.1024T>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	760841	c.1035T>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	760859	c.1053T>C	synonymous_variant	0.8	rifampicin
rpoB	760862	c.1056G>C	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoB	760877	c.1071G>T	synonymous_variant	0.89	rifampicin
rpoB	760883	c.1077G>C	synonymous_variant	0.88	rifampicin
rpoB	760886	c.1080A>G	synonymous_variant	0.84	rifampicin
rpoB	760887	p.Thr361Val	missense_variant	0.84	rifampicin	Uncertain significance
rpoB	760910	c.1104C>T	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
rpoB	760916	c.1110C>T	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	760919	c.1113C>T	synonymous_variant	0.74	rifampicin
rpoB	760925	c.1119T>C	synonymous_variant	0.78	rifampicin
rpoB	760928	c.1122G>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	760931	c.1125C>G	synonymous_variant	0.74	rifampicin
rpoB	760946	c.1140A>G	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoB	760965	p.Met387Leu	missense_variant	0.64	rifampicin	Uncertain significance
rpoB	760970	c.1164G>C	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoB	760973	c.1167G>C	synonymous_variant	0.64	rifampicin
rpoB	761132	c.1326G>T	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoB	761133	c.1327T>C	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoB	761147	c.1341C>T	synonymous_variant	0.65	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>T	synonymous_variant	0.59	rifampicin	Not assoc w R - Interim
rpoB	761165	c.1359G>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoB	761180	c.1374A>C	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoB	761189	c.1383T>C	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoB	761195	c.1389G>C	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoB	761198	c.1392G>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoB	761213	c.1407G>C	synonymous_variant	0.77	rifampicin
rpoB	761217	p.Pro471Ser	missense_variant	0.78	rifampicin
rpoB	761234	c.1428G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoB	761249	c.1443A>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	761261	c.1455G>T	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	761264	c.1458C>G	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoB	761282	c.1476C>T	synonymous_variant	0.76	rifampicin
rpoB	761288	c.1482G>T	synonymous_variant	0.74	rifampicin
rpoB	761318	c.1512G>T	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoB	761327	c.1521A>G	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoB	761330	c.1524G>C	synonymous_variant	0.73	rifampicin
rpoB	761345	c.1539G>C	synonymous_variant	0.69	rifampicin
rpoB	761354	c.1548C>T	synonymous_variant	0.72	rifampicin
rpoB	761360	c.1554T>C	synonymous_variant	0.68	rifampicin	Not assoc w R - Interim
rpoB	761362	p.Ser519Thr	missense_variant	0.65	rifampicin
rpoB	761367	p.Glu521Gln	missense_variant	0.64	rifampicin
rpoB	761374	p.Val523Asp	missense_variant	0.6	rifampicin
rpoB	761552	c.1746G>C	synonymous_variant	0.5	rifampicin
rpoB	761555	c.1749G>C	synonymous_variant	0.47	rifampicin	Not assoc w R - Interim
rpoB	761558	c.1752C>G	synonymous_variant	0.53	rifampicin	Not assoc w R - Interim
rpoB	761570	c.1764T>C	synonymous_variant	0.55	rifampicin	Not assoc w R - Interim
rpoB	761573	c.1767C>G	synonymous_variant	0.55	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>C	synonymous_variant	0.55	rifampicin	Not assoc w R - Interim
rpoB	761606	c.1800C>G	synonymous_variant	0.71	rifampicin
rpoB	761612	c.1806G>T	synonymous_variant	0.68	rifampicin	Not assoc w R - Interim
rpoB	761615	c.1809A>C	synonymous_variant	0.68	rifampicin	Not assoc w R - Interim
rpoB	761636	c.1830G>T	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoB	761645	c.1839C>G	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoB	761648	c.1842T>C	synonymous_variant	0.64	rifampicin
rpoB	761666	c.1860G>C	synonymous_variant	0.62	rifampicin
rpoB	761669	c.1863C>T	synonymous_variant	0.65	rifampicin
rpoB	761675	c.1869G>T	synonymous_variant	0.65	rifampicin
rpoB	761682	c.1876C>T	synonymous_variant	0.71	rifampicin
rpoB	761690	c.1884G>C	synonymous_variant	0.7	rifampicin
rpoB	761708	c.1902C>T	synonymous_variant	0.5	rifampicin
rpoB	761712	p.Val636Ile	missense_variant	0.47	rifampicin
rpoB	761727	p.Ser641Gly	missense_variant	0.47	rifampicin
rpoB	761736	p.Ile644Val	missense_variant	0.47	rifampicin	Uncertain significance
rpoB	761747	c.1941G>C	synonymous_variant	0.52	rifampicin
rpoB	761765	c.1959T>C	synonymous_variant	0.59	rifampicin
rpoB	761772	p.His656Ala	missense_variant	0.53	rifampicin
rpoB	761778	p.Asn658Asp	missense_variant	0.53	rifampicin
rpoB	761785	p.Thr660Ser	missense_variant	0.59	rifampicin
rpoB	761791	p.Arg662His	missense_variant	0.62	rifampicin
rpoB	761813	c.2007T>C	synonymous_variant	0.81	rifampicin
rpoB	761834	c.2028T>C	synonymous_variant	0.8	rifampicin
rpoB	761847	c.2041_2043delTGCinsCT	frameshift_variant&missense_variant	0.8	rifampicin
rpoB	761852	c.2046C>G	synonymous_variant	0.8	rifampicin
rpoB	761864	c.2058G>C	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoB	761867	c.2061C>G	synonymous_variant	0.75	rifampicin
rpoB	761868	c.2062_2064delGACinsCG	frameshift_variant&missense_variant	0.75	rifampicin
rpoB	761873	c.2067A>T	synonymous_variant	0.71	rifampicin
rpoB	761885	c.2079T>C	synonymous_variant	0.74	rifampicin
rpoB	761891	c.2085G>C	synonymous_variant	0.71	rifampicin
rpoB	761892	p.Ile696Val	missense_variant	0.71	rifampicin
rpoB	761906	c.2100C>G	synonymous_variant	0.67	rifampicin
rpoB	761909	c.2103T>C	synonymous_variant	0.67	rifampicin
rpoB	761912	c.2106T>C	synonymous_variant	0.67	rifampicin
rpoB	761915	p.Asp703Glu	missense_variant	0.67	rifampicin
rpoB	761916	p.Asp704Asn	missense_variant	0.7	rifampicin
rpoB	761921	c.2115C>T	synonymous_variant	0.71	rifampicin
rpoB	761930	c.2124G>C	synonymous_variant	0.75	rifampicin
rpoB	761948	c.2142G>C	synonymous_variant	0.7	rifampicin	Not assoc w R - Interim
rpoB	761954	c.2148C>G	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoB	761969	c.2163G>A	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoB	762008	c.2202C>T	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
rpoB	762014	c.2208C>T	synonymous_variant	0.9	rifampicin
rpoB	762047	c.2241G>A	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	762053	c.2247T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	762101	c.2295C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	762114	p.Ile770Val	missense_variant	0.94	rifampicin	Uncertain significance
rpoB	762131	c.2325C>G	synonymous_variant	0.94	rifampicin
rpoB	762137	c.2331C>T	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762140	c.2334G>C	synonymous_variant	0.91	rifampicin
rpoB	762143	c.2337T>C	synonymous_variant	0.91	rifampicin
rpoB	762149	c.2343G>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762158	c.2352G>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	762167	c.2361T>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	762176	c.2370T>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	762185	c.2379G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	762224	c.2418C>G	synonymous_variant	0.94	rifampicin
rpoB	762233	c.2427G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	762245	c.2439G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	762284	c.2478G>T	synonymous_variant	0.88	rifampicin
rpoB	762287	c.2481C>T	synonymous_variant	0.88	rifampicin
rpoB	762293	c.2487T>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoB	762308	c.2502G>C	synonymous_variant	0.88	rifampicin
rpoB	762314	c.2508C>T	synonymous_variant	0.87	rifampicin
rpoB	762317	c.2511A>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoB	762329	c.2523G>C	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
rpoB	762338	c.2532T>C	synonymous_variant	0.83	rifampicin
rpoB	762341	c.2535G>C	synonymous_variant	0.81	rifampicin
rpoB	762350	c.2544C>T	synonymous_variant	0.81	rifampicin
rpoB	762362	p.Glu852Asp	missense_variant	0.82	rifampicin
rpoB	762369	c.2563T>C	synonymous_variant	0.82	rifampicin
rpoC	762374	c.-996G>C	upstream_gene_variant	0.82	rifampicin
rpoC	762395	c.-975G>C	upstream_gene_variant	0.88	rifampicin
rpoC	762398	c.-972T>C	upstream_gene_variant	0.87	rifampicin
rpoC	762401	c.-969G>C	upstream_gene_variant	0.87	rifampicin
rpoB	762404	c.2598T>C	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
rpoC	762410	c.-960T>C	upstream_gene_variant	0.9	rifampicin
rpoB	762416	c.2610A>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	762434	c.-936T>C	upstream_gene_variant	0.93	rifampicin
rpoC	762443	c.-927G>C	upstream_gene_variant	0.91	rifampicin
rpoB	762449	c.2643C>A	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762452	c.2646G>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762470	c.2664G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoB	762491	c.2685T>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	762509	c.-861T>G	upstream_gene_variant	0.85	rifampicin
rpoB	762510	p.Ala902Pro	missense_variant	0.85	rifampicin	Uncertain significance
rpoB	762515	c.2709C>T	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	762527	c.-843G>C	upstream_gene_variant	0.8	rifampicin
rpoC	762533	c.-837T>A	upstream_gene_variant	0.74	rifampicin
rpoC	762536	c.-834T>C	upstream_gene_variant	0.69	rifampicin
rpoC	762537	c.-833T>C	upstream_gene_variant	0.73	rifampicin
rpoC	762551	c.-819C>T	upstream_gene_variant	0.65	rifampicin
rpoC	762560	c.-810A>T	upstream_gene_variant	0.65	rifampicin
rpoC	762563	c.-807G>T	upstream_gene_variant	0.62	rifampicin
rpoC	762827	c.-543G>T	upstream_gene_variant	0.59	rifampicin
rpoB	762833	c.3027C>T	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	762839	c.-531G>A	upstream_gene_variant	0.67	rifampicin
rpoB	762857	c.3051C>G	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoB	762863	c.3057T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoB	762879	c.3073_3075delATGinsCC	frameshift_variant&missense_variant	0.88	rifampicin
rpoB	762917	c.3111C>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762920	c.3114C>T	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	762929	c.3123G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	762959	c.3153G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	762962	c.3156C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	762995	c.3189G>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	763004	c.3198G>A	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	763007	c.3201C>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	763022	c.-348C>G	upstream_gene_variant	0.94	rifampicin
rpoB	763028	c.3222T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	763031	c.3225T>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	763053	c.3247T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	763070	c.3264T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	763085	c.3279C>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	763103	c.-267G>C	upstream_gene_variant	0.86	rifampicin
rpoB	763115	c.3309T>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoB	763127	c.3321G>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoB	763130	c.3324G>A	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoC	763133	c.-237G>C	upstream_gene_variant	0.73	rifampicin
rpoB	763136	c.3330C>T	synonymous_variant	0.72	rifampicin	Not assoc w R - Interim
rpoC	763142	c.-228C>G	upstream_gene_variant	0.74	rifampicin
rpoC	763160	c.-210G>T	upstream_gene_variant	0.72	rifampicin
rpoC	763169	c.-201A>G	upstream_gene_variant	0.7	rifampicin
rpoC	763190	c.-180C>T	upstream_gene_variant	0.62	rifampicin
rpoC	763199	c.-171G>C	upstream_gene_variant	0.57	rifampicin
rpoC	763202	c.-168A>G	upstream_gene_variant	0.57	rifampicin
rpoC	763205	c.-165G>T	upstream_gene_variant	0.55	rifampicin
rpoC	763206	c.-164_-163delAGinsTC	upstream_gene_variant	0.55	rifampicin
rpoC	763217	c.-153G>C	upstream_gene_variant	0.61	rifampicin
rpoC	763226	c.-144A>G	upstream_gene_variant	0.58	rifampicin
rpoB	763227	p.Leu1141Met	missense_variant	0.58	rifampicin
rpoC	763232	c.-138C>T	upstream_gene_variant	0.58	rifampicin
rpoB	763235	p.Glu1143Asp	missense_variant	0.61	rifampicin
rpoB	763241	p.Glu1145Asp	missense_variant	0.63	rifampicin
rpoC	763259	c.-111G>C	upstream_gene_variant	0.67	rifampicin
rpoC	763262	c.-108C>T	upstream_gene_variant	0.67	rifampicin
rpoC	763265	c.-105G>C	upstream_gene_variant	0.71	rifampicin
rpoB	763268	c.3462C>G	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoC	763271	c.-99C>T	upstream_gene_variant	0.71	rifampicin
rpoB	763283	c.3477T>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoC	763375	c.6C>A	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	763408	c.39T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	763411	c.42T>C	synonymous_variant	0.91	rifampicin
rpoC	763414	c.45T>C	synonymous_variant	0.91	rifampicin
rpoC	763423	p.Glu18Asp	missense_variant	0.91	rifampicin	Uncertain significance
rpoC	763430	c.61_63delAGGinsCT	frameshift_variant&missense_variant	0.91	rifampicin
rpoC	763433	c.64_66delCAAinsAC	frameshift_variant&missense_variant	0.91	rifampicin
rpoC	763443	p.Tyr25Phe	missense_variant	0.84	rifampicin
rpoC	763456	c.87A>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	763468	c.99G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	763486	c.117T>C	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	763492	c.123G>T	synonymous_variant	0.85	rifampicin
rpoC	763528	c.159G>A	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	763546	c.177A>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	763558	c.189C>T	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	763573	c.204G>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	763594	c.225C>T	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	763603	c.234C>T	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	763615	c.246G>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	763618	c.249C>T	synonymous_variant	0.88	rifampicin
rpoC	763633	c.264T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	763660	c.291T>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	763666	c.297G>A	synonymous_variant	0.9	rifampicin
rpoC	763675	c.306C>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	763702	c.333C>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	763709	c.340C>T	synonymous_variant	0.88	rifampicin
rpoC	763714	c.345G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	763717	c.348T>C	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	763723	c.354G>C	synonymous_variant	0.87	rifampicin
rpoC	763732	c.363C>T	synonymous_variant	0.86	rifampicin
rpoC	763741	c.372C>T	synonymous_variant	0.89	rifampicin
rpoC	763747	c.378G>A	synonymous_variant	0.92	rifampicin
rpoC	763765	c.396T>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	763792	p.Glu141Asp	missense_variant	0.9	rifampicin
rpoC	763807	c.438T>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	763813	c.444C>G	synonymous_variant	0.9	rifampicin
rpoC	763831	c.462A>G	synonymous_variant	0.88	rifampicin
rpoC	763837	c.468G>C	synonymous_variant	0.88	rifampicin
rpoC	763840	c.471G>C	synonymous_variant	0.88	rifampicin
rpoC	763858	c.489A>G	synonymous_variant	0.88	rifampicin
rpoC	763861	c.492C>T	synonymous_variant	0.86	rifampicin
rpoC	763872	p.Gly168Ala	missense_variant	0.85	rifampicin
rpoC	763876	p.Glu169Asp	missense_variant	0.85	rifampicin
rpoC	763879	c.510A>G	synonymous_variant	0.83	rifampicin
rpoC	763882	c.513G>A	synonymous_variant	0.83	rifampicin
rpoC	763891	c.522G>C	synonymous_variant	0.83	rifampicin
rpoC	763894	c.525A>G	synonymous_variant	0.83	rifampicin
rpoC	763900	c.531G>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	763921	c.552G>C	synonymous_variant	0.85	rifampicin
rpoC	763924	c.555G>A	synonymous_variant	0.85	rifampicin
rpoC	763930	c.561G>A	synonymous_variant	0.8	rifampicin
rpoC	763933	c.564C>T	synonymous_variant	0.78	rifampicin	Not assoc w R - Interim
rpoC	763940	p.Ala191Ser	missense_variant	0.78	rifampicin	Uncertain significance
rpoC	763945	c.576T>C	synonymous_variant	0.77	rifampicin
rpoC	763947	p.Ala193Val	missense_variant	0.77	rifampicin	Uncertain significance
rpoC	763951	c.582G>C	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoC	763960	c.591T>G	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoC	763969	c.600C>T	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	764131	c.762T>C	synonymous_variant	0.78	rifampicin
rpoC	764134	c.765C>G	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoC	764153	p.Gln262Lys	missense_variant	0.79	rifampicin
rpoC	764161	c.792G>C	synonymous_variant	0.78	rifampicin
rpoC	764182	p.Asp271Glu	missense_variant	0.78	rifampicin	Uncertain significance
rpoC	764188	c.819A>G	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	764195	c.826_828delTCGinsAGC	synonymous_variant	0.71	rifampicin
rpoC	764203	c.834G>C	synonymous_variant	0.7	rifampicin
rpoC	764206	p.Asp279Glu	missense_variant	0.69	rifampicin
rpoC	764207	p.Val280Thr	missense_variant	0.67	rifampicin	Uncertain significance
rpoC	764215	c.846A>C	synonymous_variant	0.7	rifampicin
rpoC	764217	p.Asn283Ser	missense_variant	0.7	rifampicin
rpoC	764239	c.870T>G	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoC	764254	c.885G>C	synonymous_variant	0.76	rifampicin
rpoC	764257	c.888G>C	synonymous_variant	0.76	rifampicin
rpoC	764263	c.894G>C	synonymous_variant	0.77	rifampicin
rpoC	764266	c.897T>C	synonymous_variant	0.77	rifampicin
rpoC	764272	c.903G>C	synonymous_variant	0.78	rifampicin
rpoC	764278	c.909A>G	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoC	764293	c.924G>C	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
rpoC	764297	p.Met310Leu	missense_variant	0.8	rifampicin
rpoC	764344	c.975C>T	synonymous_variant	0.84	rifampicin
rpoC	764353	c.984G>T	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoC	764365	c.996C>T	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764371	c.1002G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764380	c.1011G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764387	c.1018T>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764405	c.1036_1038delAGGinsCC	frameshift_variant&missense_variant	0.85	rifampicin
rpoC	764431	c.1062G>C	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	764434	c.1065A>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	764435	c.1066_1068delAGGinsCA	frameshift_variant&missense_variant	0.84	rifampicin
rpoC	764446	c.1077T>C	synonymous_variant	0.86	rifampicin
rpoC	764449	c.1080G>C	synonymous_variant	0.86	rifampicin
rpoC	764458	c.1089G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764461	c.1092A>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764485	c.1116G>C	synonymous_variant	0.93	rifampicin
rpoC	764491	c.1122G>T	synonymous_variant	0.93	rifampicin
rpoC	764497	c.1128A>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764500	c.1131C>G	synonymous_variant	0.89	rifampicin
rpoC	764521	c.1152T>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	764536	c.1167G>T	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764539	c.1170C>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764575	c.1206T>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764605	c.1236G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764611	c.1242G>T	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764623	c.1254C>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764626	c.1257C>T	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	764632	c.1263T>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>T	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	764701	c.1332C>G	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	764713	c.1344G>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	764716	c.1347G>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	764746	c.1377G>T	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764752	c.1383G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764758	c.1389C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764764	c.1395T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	764803	c.1434C>T	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
rpoC	764809	c.1440C>T	synonymous_variant	0.87	rifampicin	Not assoc w R
rpoC	764815	c.1446A>G	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
rpoC	764824	c.1455T>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	764827	c.1458G>C	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoC	764851	c.1482C>T	synonymous_variant	0.87	rifampicin
rpoC	764858	c.1489T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoC	764869	c.1500C>T	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	764875	c.1506C>T	synonymous_variant	0.86	rifampicin
rpoC	764878	c.1509C>G	synonymous_variant	0.85	rifampicin
rpoC	764887	c.1518G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764888	c.1519T>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	764911	c.1542A>G	synonymous_variant	0.81	rifampicin
rpoC	764912	p.Met515Gln	missense_variant	0.81	rifampicin	Uncertain significance
rpoC	764932	c.1563C>A	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	764935	c.1566T>C	synonymous_variant	0.82	rifampicin
rpoC	764948	c.1579T>C	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	764968	c.1599T>C	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
rpoC	765007	c.1638T>G	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoC	765008	c.1639T>C	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoC	765011	c.1642_1644delAGCinsTCG	synonymous_variant	0.71	rifampicin
rpoC	765016	c.1647C>A	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	765022	c.1653G>T	synonymous_variant	0.62	rifampicin
rpoC	765034	c.1665T>C	synonymous_variant	0.62	rifampicin
rpoC	765040	c.1671T>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	765041	c.1672T>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	765047	c.1678T>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	765055	c.1686C>G	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	765338	p.Gln657Lys	missense_variant	0.47	rifampicin
rpoC	765352	c.1983G>C	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoC	765357	p.Met663Thr	missense_variant	0.62	rifampicin
rpoC	765361	c.1992C>G	synonymous_variant	0.71	rifampicin
rpoC	765383	p.Met672Leu	missense_variant	0.79	rifampicin	Uncertain significance
rpoC	765400	c.2031G>C	synonymous_variant	0.82	rifampicin
rpoC	765403	c.2034G>C	synonymous_variant	0.81	rifampicin
rpoC	765404	p.Leu679Lys	missense_variant	0.81	rifampicin
rpoC	765409	c.2040T>C	synonymous_variant	0.81	rifampicin
rpoC	765412	c.2043T>C	synonymous_variant	0.82	rifampicin
rpoC	765425	p.Lys686Glu	missense_variant	0.89	rifampicin
rpoC	765445	c.2076G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoC	765452	p.Ala695Arg	missense_variant	0.89	rifampicin
rpoC	765466	c.2097C>T	synonymous_variant	1.0	rifampicin
rpoC	765478	c.2109T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765480	p.Tyr704Phe	missense_variant	0.94	rifampicin	Uncertain significance
rpoC	765496	c.2127C>G	synonymous_variant	0.92	rifampicin
rpoC	765499	c.2130C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	765772	c.2403C>G	synonymous_variant	0.76	rifampicin
rpoC	765778	c.2409C>G	synonymous_variant	0.76	rifampicin
rpoC	765779	c.2410_2412delGACinsAG	frameshift_variant&missense_variant	0.76	rifampicin
rpoC	765793	c.2424C>G	synonymous_variant	0.82	rifampicin
rpoC	765796	c.2427C>T	synonymous_variant	0.86	rifampicin
rpoC	765800	p.Phe811Leu	missense_variant	0.86	rifampicin
rpoC	765811	c.2442T>G	synonymous_variant	0.88	rifampicin
rpoC	765814	c.2445A>C	synonymous_variant	0.84	rifampicin
rpoC	765817	c.2448G>C	synonymous_variant	0.85	rifampicin
rpoC	765823	c.2454C>A	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	765826	c.2457T>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	765835	c.2466C>T	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
rpoC	765871	c.2502T>C	synonymous_variant	0.91	rifampicin
rpoC	765875	p.Val836Ile	missense_variant	0.92	rifampicin	Uncertain significance
rpoC	765886	c.2517C>G	synonymous_variant	0.93	rifampicin
rpoC	765904	c.2535C>G	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoC	765908	c.2539C>T	synonymous_variant	0.89	rifampicin
rpoC	765934	c.2565C>T	synonymous_variant	0.84	rifampicin
rpoC	765940	c.2571A>T	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoC	765946	c.2577C>T	synonymous_variant	0.79	rifampicin
rpoC	765947	c.2578T>C	synonymous_variant	0.78	rifampicin	Not assoc w R - Interim
rpoC	765952	c.2583G>C	synonymous_variant	0.78	rifampicin
rpoC	765961	c.2592G>T	synonymous_variant	0.77	rifampicin
rpoC	765962	c.2593T>C	synonymous_variant	0.77	rifampicin
rpoC	765967	c.2598C>T	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoC	765979	c.2610C>G	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	765982	c.2613C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	765994	c.2625A>T	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoC	766012	c.2643C>G	synonymous_variant	0.62	rifampicin	Not assoc w R - Interim
rpoC	766021	c.2652G>C	synonymous_variant	0.58	rifampicin
rpoC	766645	c.3276A>G	synonymous_variant	0.43	rifampicin
rpoC	766651	c.3282T>C	synonymous_variant	0.43	rifampicin
rpoC	766658	c.3289_3291delCGGinsGC	frameshift_variant&missense_variant	0.5	rifampicin
rpoC	766666	c.3297C>G	synonymous_variant	0.58	rifampicin
rpoC	766672	c.3303T>C	synonymous_variant	0.6	rifampicin
rpoC	766675	c.3306C>T	synonymous_variant	0.6	rifampicin
rpoC	766690	c.3321G>C	synonymous_variant	0.68	rifampicin
rpoC	766694	c.3325_3327delCAGinsGC	frameshift_variant&missense_variant	0.7	rifampicin
rpoC	766714	c.3345G>C	synonymous_variant	0.72	rifampicin
rpoC	766717	c.3348C>G	synonymous_variant	0.72	rifampicin
rpoC	766720	c.3351C>T	synonymous_variant	0.72	rifampicin
rpoC	766726	c.3357T>C	synonymous_variant	0.73	rifampicin
rpoC	766738	c.3369G>T	synonymous_variant	0.75	rifampicin
rpoC	766741	c.3372G>C	synonymous_variant	0.77	rifampicin
rpoC	766765	c.3396A>C	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoC	766771	c.3402G>C	synonymous_variant	0.74	rifampicin
rpoC	766774	c.3405T>C	synonymous_variant	0.74	rifampicin
rpoC	766775	p.Arg1136Lys	missense_variant	0.74	rifampicin
rpoC	766798	c.3429C>G	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoC	766804	c.3435A>G	synonymous_variant	0.78	rifampicin	Not assoc w R - Interim
rpoC	766978	c.3609C>T	synonymous_variant	0.73	rifampicin
rpoC	766981	c.3612T>C	synonymous_variant	0.76	rifampicin
rpoC	766996	c.3627C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoC	767002	c.3633G>C	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoC	767008	c.3639G>A	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoC	767023	c.3654C>T	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
rpoC	767098	c.3729T>C	synonymous_variant	0.85	rifampicin	Not assoc w R - Interim
rpoC	767104	c.3735C>G	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	767105	c.3736_3738delAACinsCG	frameshift_variant&missense_variant	0.84	rifampicin
rpoC	767119	c.3750A>G	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	767134	c.3765C>T	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoC	767138	c.3769C>T	synonymous_variant	0.84	rifampicin	Not assoc w R - Interim
rpoC	767158	c.3789T>C	synonymous_variant	0.73	rifampicin	Not assoc w R - Interim
rpoC	767162	p.Asn1265Ala	missense_variant	0.71	rifampicin
rpoC	767167	c.3798C>T	synonymous_variant	0.74	rifampicin
rpoC	767174	p.Asn1269Asp	missense_variant	0.73	rifampicin
rpoC	767180	p.Ala1271Gln	missense_variant	0.7	rifampicin
rpoC	767191	c.3822C>G	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoC	767197	c.3828G>A	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
rpoC	767221	c.3852C>G	synonymous_variant	0.53	rifampicin	Not assoc w R - Interim
rpoC	767230	c.3861G>C	synonymous_variant	0.44	rifampicin	Not assoc w R - Interim
rpoC	767233	c.3864T>C	synonymous_variant	0.44	rifampicin	Not assoc w R - Interim
mmpL5	775829	c.2652C>A	synonymous_variant	0.62	clofazimine
mmpL5	775829	c.2652C>A	synonymous_variant	0.62	bedaquiline
mmpL5	775832	c.2647_2649delGCCinsTG	frameshift_variant&missense_variant	0.52	clofazimine	Uncertain significance
mmpL5	775832	c.2647_2649delGCCinsTG	frameshift_variant&missense_variant	0.52	bedaquiline	Uncertain significance
mmpL5	775838	c.2643G>C	synonymous_variant	0.58	clofazimine
mmpL5	775838	c.2643G>C	synonymous_variant	0.58	bedaquiline
mmpL5	775851	p.Ser877Thr	missense_variant	0.7	clofazimine
mmpL5	775851	p.Ser877Thr	missense_variant	0.7	bedaquiline
mmpL5	775856	c.2625T>C	synonymous_variant	0.81	clofazimine
mmpL5	775856	c.2625T>C	synonymous_variant	0.81	bedaquiline
mmpL5	775865	c.2616T>C	synonymous_variant	0.78	clofazimine
mmpL5	775865	c.2616T>C	synonymous_variant	0.78	bedaquiline
mmpL5	775877	c.2604C>G	synonymous_variant	0.64	clofazimine
mmpL5	775877	c.2604C>G	synonymous_variant	0.64	bedaquiline
mmpL5	775883	c.2596_2598delATCinsTG	frameshift_variant&missense_variant	0.64	clofazimine	Uncertain significance
mmpL5	775883	c.2596_2598delATCinsTG	frameshift_variant&missense_variant	0.64	bedaquiline	Uncertain significance
mmpL5	775886	c.2595A>C	synonymous_variant	0.75	clofazimine
mmpL5	775886	c.2595A>C	synonymous_variant	0.75	bedaquiline
mmpL5	775892	c.2589C>T	synonymous_variant	0.7	clofazimine
mmpL5	775892	c.2589C>T	synonymous_variant	0.7	bedaquiline
mmpL5	775904	c.2577G>A	synonymous_variant	0.81	clofazimine
mmpL5	775904	c.2577G>A	synonymous_variant	0.81	bedaquiline
mmpL5	775909	p.Leu858Phe	missense_variant	0.71	clofazimine
mmpL5	775909	p.Leu858Phe	missense_variant	0.71	bedaquiline
mmpL5	775915	p.Ala856Ser	missense_variant	0.7	clofazimine
mmpL5	775915	p.Ala856Ser	missense_variant	0.7	bedaquiline
mmpL5	775916	c.2565T>C	synonymous_variant	0.78	clofazimine
mmpL5	775916	c.2565T>C	synonymous_variant	0.78	bedaquiline
mmpL5	775921	c.2560C>T	synonymous_variant	0.76	clofazimine
mmpL5	775921	c.2560C>T	synonymous_variant	0.76	bedaquiline
mmpL5	775924	c.2557C>T	synonymous_variant	0.78	clofazimine	Not assoc w R - Interim
mmpL5	775924	c.2557C>T	synonymous_variant	0.78	bedaquiline
mmpL5	775940	c.2541C>T	synonymous_variant	0.34	clofazimine
mmpL5	775940	c.2541C>T	synonymous_variant	0.34	bedaquiline
mmpL5	775951	c.2530C>T	synonymous_variant	0.9	clofazimine
mmpL5	775951	c.2530C>T	synonymous_variant	0.9	bedaquiline
mmpL5	775955	c.2524_2526delATCinsGG	frameshift_variant&missense_variant	0.57	clofazimine	Uncertain significance
mmpL5	775955	c.2524_2526delATCinsGG	frameshift_variant&missense_variant	0.57	bedaquiline	Uncertain significance
mmpL5	775964	c.2515_2517delGCGinsTC	frameshift_variant&missense_variant	0.48	clofazimine	Uncertain significance
mmpL5	775964	c.2515_2517delGCGinsTC	frameshift_variant&missense_variant	0.48	bedaquiline	Uncertain significance
mmpL5	775973	c.2506_2508delTTGinsAC	frameshift_variant&missense_variant	0.5	clofazimine	Uncertain significance
mmpL5	775973	c.2506_2508delTTGinsAC	frameshift_variant&missense_variant	0.5	bedaquiline	Uncertain significance
mmpL5	775981	p.Leu834Met	missense_variant	0.9	clofazimine
mmpL5	775981	p.Leu834Met	missense_variant	0.9	bedaquiline
mmpL5	775994	c.2485_2487delATCinsCG	frameshift_variant&missense_variant	0.84	clofazimine	Uncertain significance
mmpL5	775994	c.2485_2487delATCinsCG	frameshift_variant&missense_variant	0.84	bedaquiline	Uncertain significance
mmpL5	775997	c.2484T>G	synonymous_variant	0.79	clofazimine
mmpL5	775997	c.2484T>G	synonymous_variant	0.79	bedaquiline
mmpL5	776000	c.2479_2481delCTGinsAC	frameshift_variant&missense_variant	0.79	clofazimine	Uncertain significance
mmpL5	776000	c.2479_2481delCTGinsAC	frameshift_variant&missense_variant	0.79	bedaquiline	Uncertain significance
mmpL5	776003	c.2476_2478delATCinsCG	frameshift_variant&missense_variant	0.37	clofazimine	Uncertain significance
mmpL5	776003	c.2476_2478delATCinsCG	frameshift_variant&missense_variant	0.37	bedaquiline	Uncertain significance
mmpL5	776030	c.2451G>C	synonymous_variant	0.85	clofazimine
mmpL5	776030	c.2451G>C	synonymous_variant	0.85	bedaquiline
mmpL5	776047	c.2434C>T	synonymous_variant	0.38	clofazimine
mmpL5	776047	c.2434C>T	synonymous_variant	0.38	bedaquiline
mmpL5	776053	c.2428T>C	synonymous_variant	0.87	clofazimine
mmpL5	776053	c.2428T>C	synonymous_variant	0.87	bedaquiline
mmpL5	776081	c.2400G>C	synonymous_variant	0.64	clofazimine
mmpL5	776081	c.2400G>C	synonymous_variant	0.64	bedaquiline
rpsL	781572	c.13_15delCAGinsAC	frameshift_variant&missense_variant	0.64	streptomycin	Uncertain significance
rpsL	781595	c.36T>C	synonymous_variant	0.71	streptomycin
rpsL	781598	c.39G>C	synonymous_variant	0.71	streptomycin
rpsL	781605	p.Ile16Val	missense_variant	0.71	streptomycin	Uncertain significance
rpsL	781608	p.Ser17Ala	missense_variant	0.71	streptomycin
rpsL	781628	c.69T>C	synonymous_variant	0.74	streptomycin	Not assoc w R - Interim
rpsL	781631	c.72G>C	synonymous_variant	0.7	streptomycin
rpsL	781649	c.90T>C	synonymous_variant	0.72	streptomycin
rpsL	781655	c.96T>C	synonymous_variant	0.72	streptomycin
rpsL	781658	c.99A>G	synonymous_variant	0.74	streptomycin
rpsL	781682	c.123T>C	synonymous_variant	0.76	streptomycin
rpsL	781709	c.150G>C	synonymous_variant	0.78	streptomycin	Not assoc w R - Interim
rpsL	781715	c.156T>C	synonymous_variant	0.77	streptomycin
rpsL	781728	c.169T>C	synonymous_variant	0.71	streptomycin
rpsL	781732	c.174_177delGAGT	frameshift_variant	0.7	streptomycin	Uncertain significance
rpsL	781739	c.180_181insCGGC	frameshift_variant	0.73	streptomycin	Uncertain significance
rpsL	781742	c.183C>T	synonymous_variant	0.74	streptomycin
rpsL	781751	c.192G>C	synonymous_variant	0.76	streptomycin
rpsL	781760	c.201T>C	synonymous_variant	0.79	streptomycin
rpsL	781772	c.213C>T	synonymous_variant	0.83	streptomycin	Not assoc w R - Interim
rpsL	781808	c.249C>T	synonymous_variant	0.91	streptomycin
rpsL	781814	c.255C>T	synonymous_variant	0.91	streptomycin
rpsL	781817	c.258G>T	synonymous_variant	0.91	streptomycin
rpsL	781829	c.270G>C	synonymous_variant	0.9	streptomycin
rpsL	781832	c.273T>C	synonymous_variant	0.9	streptomycin
rpsL	781838	c.279G>C	synonymous_variant	0.91	streptomycin
rpsL	781841	c.282C>T	synonymous_variant	0.91	streptomycin
rpsL	781859	c.300T>G	synonymous_variant	0.9	streptomycin
rpsL	781865	c.306G>C	synonymous_variant	0.88	streptomycin
rpsL	781868	c.309T>C	synonymous_variant	0.88	streptomycin
rpsL	781871	c.312G>C	synonymous_variant	0.88	streptomycin
rpsL	781892	c.333A>G	synonymous_variant	0.82	streptomycin
rpsL	781898	c.339A>C	synonymous_variant	0.82	streptomycin
rpsL	781901	c.342C>T	synonymous_variant	0.82	streptomycin
rpsL	781907	c.348T>C	synonymous_variant	0.81	streptomycin
rpsL	781916	c.357T>C	synonymous_variant	0.79	streptomycin
rpsL	781929	p.Gly124Ser	missense_variant	0.77	streptomycin	Uncertain significance
rplC	800516	c.-293G>C	upstream_gene_variant	0.57	linezolid
rplC	800543	c.-266C>T	upstream_gene_variant	0.68	linezolid
rplC	800546	c.-263T>C	upstream_gene_variant	0.69	linezolid
rplC	800570	c.-239C>G	upstream_gene_variant	0.8	linezolid
rplC	800574	c.-235_-234delGTinsAC	upstream_gene_variant	0.8	linezolid
rplC	800579	c.-230C>T	upstream_gene_variant	0.8	linezolid
rplC	800594	c.-215C>G	upstream_gene_variant	0.8	linezolid
rplC	800597	c.-212A>G	upstream_gene_variant	0.8	linezolid
rplC	800600	c.-209G>C	upstream_gene_variant	0.8	linezolid
rplC	800603	c.-206G>C	upstream_gene_variant	0.82	linezolid
rplC	800612	c.-197A>G	upstream_gene_variant	0.84	linezolid
rplC	800618	c.-191T>C	upstream_gene_variant	0.86	linezolid
rplC	800633	c.-176T>C	upstream_gene_variant	0.88	linezolid
rplC	800645	c.-164C>G	upstream_gene_variant	0.91	linezolid
rplC	800648	c.-161A>G	upstream_gene_variant	0.88	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	0.88	linezolid
rplC	800678	c.-131C>T	upstream_gene_variant	0.83	linezolid
rplC	800684	c.-125G>A	upstream_gene_variant	0.81	linezolid
rplC	800693	c.-116A>C	upstream_gene_variant	0.86	linezolid
rplC	800702	c.-107G>A	upstream_gene_variant	0.79	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	0.8	linezolid
rplC	800715	c.-94A>C	upstream_gene_variant	0.75	linezolid
rplC	800720	c.-89T>C	upstream_gene_variant	0.75	linezolid
rplC	800723	c.-86C>G	upstream_gene_variant	0.71	linezolid
rplC	800735	c.-74C>G	upstream_gene_variant	0.69	linezolid
rplC	800762	c.-47T>G	upstream_gene_variant	0.6	linezolid
rplC	800771	c.-38C>T	upstream_gene_variant	0.5	linezolid
rplC	800937	c.129A>G	synonymous_variant	0.67	linezolid
rplC	800946	c.138T>C	synonymous_variant	0.68	linezolid
rplC	800949	c.141T>C	synonymous_variant	0.68	linezolid
rplC	800964	c.156G>C	synonymous_variant	0.71	linezolid
rplC	800985	c.177A>G	synonymous_variant	0.75	linezolid
rplC	801252	c.444G>C	synonymous_variant	0.69	linezolid
rplC	801264	c.456C>T	synonymous_variant	0.57	linezolid
rplC	801267	c.459A>C	synonymous_variant	0.57	linezolid
rplC	801276	c.468G>C	synonymous_variant	0.57	linezolid
rplC	801281	p.Ala158Gly	missense_variant	0.57	linezolid
rplC	801285	c.477G>C	synonymous_variant	0.57	linezolid
rplC	801307	c.499_501delGCCinsTG	frameshift_variant&missense_variant	0.55	linezolid
rplC	801312	c.504G>C	synonymous_variant	0.55	linezolid
rplC	801315	c.507G>T	synonymous_variant	0.5	linezolid
rplC	801324	c.516T>C	synonymous_variant	0.55	linezolid
fbiC	1303509	c.579G>C	synonymous_variant	0.56	clofazimine
					pretomanid
					delamanid
fbiC	1303512	c.582T>G	synonymous_variant	0.6	clofazimine
					pretomanid
					delamanid
fbiC	1303531	p.Met201Leu	missense_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1303536	c.606G>A	synonymous_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1303539	c.609G>C	synonymous_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1303545	c.615A>G	synonymous_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1303548	c.618G>C	synonymous_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1303551	c.621G>T	synonymous_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1303554	c.624G>A	synonymous_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1303581	c.651G>C	synonymous_variant	0.65	clofazimine
					pretomanid
					delamanid
fbiC	1303584	c.654C>G	synonymous_variant	0.68	clofazimine
					pretomanid
					delamanid
fbiC	1303587	c.657G>C	synonymous_variant	0.68	clofazimine
					pretomanid
					delamanid
fbiC	1303593	c.663G>C	synonymous_variant	0.65	clofazimine
					pretomanid
					delamanid
fbiC	1303602	c.672A>G	synonymous_variant	0.62	clofazimine
					pretomanid
					delamanid
fbiC	1303611	c.681G>C	synonymous_variant	0.62	clofazimine
					pretomanid
					delamanid
fbiC	1303612	p.Leu228Glu	missense_variant	0.62	clofazimine
					pretomanid
					delamanid
fbiC	1303629	c.699C>T	synonymous_variant	0.62	clofazimine
					pretomanid
					delamanid
fbiC	1303632	c.702T>C	synonymous_variant	0.62	clofazimine
					pretomanid
					delamanid
fbiC	1303644	c.714G>C	synonymous_variant	0.53	clofazimine
					pretomanid
					delamanid
fbiC	1304515	p.Ala529Thr	missense_variant	0.41	clofazimine
					pretomanid
					delamanid
fbiC	1304526	c.1596T>G	synonymous_variant	0.41	clofazimine
					pretomanid
					delamanid
fbiC	1304533	c.1603T>C	synonymous_variant	0.41	clofazimine
					pretomanid
					delamanid
fbiC	1304541	c.1611C>A	synonymous_variant	0.41	clofazimine
					pretomanid
					delamanid
fbiC	1304544	c.1614T>C	synonymous_variant	0.41	clofazimine
					pretomanid
					delamanid
fbiC	1304546	p.Val539Ala	missense_variant	0.44	clofazimine
					pretomanid
					delamanid
fbiC	1304559	p.Glu543Asp	missense_variant	0.64	clofazimine
					pretomanid
					delamanid
fbiC	1304562	c.1632G>C	synonymous_variant	0.68	clofazimine
					pretomanid
					delamanid
fbiC	1304567	p.Phe546Tyr	missense_variant	0.7	clofazimine
					pretomanid
					delamanid
fbiC	1304571	c.1641G>C	synonymous_variant	0.73	clofazimine
					pretomanid
					delamanid
fbiC	1304580	c.1650T>C	synonymous_variant	0.76	clofazimine
					pretomanid
					delamanid
fbiC	1304613	c.1683T>C	synonymous_variant	0.87	clofazimine
					pretomanid
					delamanid
fbiC	1304634	c.1704C>G	synonymous_variant	0.84	clofazimine
					pretomanid
					delamanid
fbiC	1304640	c.1710A>C	synonymous_variant	0.83	clofazimine
					pretomanid
					delamanid
fbiC	1304646	c.1716T>C	synonymous_variant	0.87	clofazimine
					pretomanid
					delamanid
fbiC	1304670	c.1740G>C	synonymous_variant	0.85	clofazimine
					pretomanid
					delamanid
fbiC	1304671	p.Val581Thr	missense_variant	0.85	clofazimine
					pretomanid
					delamanid
fbiC	1304675	p.Gly582Asp	missense_variant	0.85	clofazimine
					pretomanid
					delamanid
fbiC	1304694	c.1764A>G	synonymous_variant	0.82	clofazimine
					pretomanid
					delamanid
fbiC	1304715	c.1785G>T	synonymous_variant	0.79	clofazimine
					pretomanid
					delamanid
fbiC	1304724	c.1794A>G	synonymous_variant	0.76	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304727	c.1797A>C	synonymous_variant	0.74	clofazimine
					pretomanid
					delamanid
fbiC	1304742	c.1812T>C	synonymous_variant	0.71	clofazimine
					pretomanid
					delamanid
fbiC	1304751	c.1821C>G	synonymous_variant	0.61	clofazimine
					pretomanid
					delamanid
fbiC	1304757	c.1827A>G	synonymous_variant	0.58	clofazimine
					pretomanid
					delamanid
fbiC	1304760	c.1830G>C	synonymous_variant	0.56	clofazimine
					pretomanid
					delamanid
fbiC	1304769	c.1839C>G	synonymous_variant	0.6	clofazimine
					pretomanid
					delamanid
fbiC	1304772	c.1842C>T	synonymous_variant	0.57	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
sigE	1364640	c.228G>C	synonymous_variant	0.64	pyrazinamide
sigE	1364643	c.231C>T	synonymous_variant	0.64	pyrazinamide
sigE	1364644	p.Lys78Gln	missense_variant	0.64	pyrazinamide
sigE	1364650	p.Thr80Ala	missense_variant	0.69	pyrazinamide	Uncertain significance
sigE	1364661	c.249C>G	synonymous_variant	0.72	pyrazinamide
sigE	1364679	c.267T>C	synonymous_variant	0.8	pyrazinamide
sigE	1364682	c.270G>A	synonymous_variant	0.85	pyrazinamide
sigE	1364691	c.279T>C	synonymous_variant	0.84	pyrazinamide
sigE	1364709	c.297T>C	synonymous_variant	0.84	pyrazinamide
sigE	1364712	c.300T>C	synonymous_variant	0.85	pyrazinamide
sigE	1364721	c.309C>G	synonymous_variant	0.85	pyrazinamide
sigE	1364724	c.312C>T	synonymous_variant	0.85	pyrazinamide
sigE	1364736	c.324T>C	synonymous_variant	0.9	pyrazinamide	Not assoc w R - Interim
sigE	1364742	c.330A>G	synonymous_variant	0.93	pyrazinamide
sigE	1364763	c.351T>C	synonymous_variant	0.93	pyrazinamide
sigE	1364767	c.355A>C	synonymous_variant	0.93	pyrazinamide
sigE	1364781	c.369G>C	synonymous_variant	0.88	pyrazinamide
sigE	1364784	c.372C>G	synonymous_variant	0.86	pyrazinamide
sigE	1364790	c.378T>C	synonymous_variant	0.86	pyrazinamide
sigE	1364796	c.384G>A	synonymous_variant	0.85	pyrazinamide
sigE	1364799	c.387G>C	synonymous_variant	0.85	pyrazinamide
sigE	1364802	c.390C>A	synonymous_variant	0.86	pyrazinamide
sigE	1364811	c.399A>G	synonymous_variant	0.81	pyrazinamide
sigE	1364814	c.402C>G	synonymous_variant	0.8	pyrazinamide
sigE	1364820	c.408A>G	synonymous_variant	0.79	pyrazinamide
sigE	1364839	c.427T>C	synonymous_variant	0.76	pyrazinamide
sigE	1364847	c.435G>C	synonymous_variant	0.78	pyrazinamide
sigE	1364865	c.453G>C	synonymous_variant	0.75	pyrazinamide
sigE	1364867	p.Ala152Gly	missense_variant	0.75	pyrazinamide
sigE	1364871	c.459C>T	synonymous_variant	0.75	pyrazinamide
sigE	1364877	c.465G>T	synonymous_variant	0.79	pyrazinamide
sigE	1364883	c.471G>A	synonymous_variant	0.79	pyrazinamide
sigE	1364887	c.475_477delTTAinsCG	frameshift_variant&missense_variant	0.79	pyrazinamide	Uncertain significance
sigE	1364898	c.486C>T	synonymous_variant	0.8	pyrazinamide
sigE	1364919	c.507T>C	synonymous_variant	0.86	pyrazinamide
sigE	1364922	p.Glu170Asp	missense_variant	0.86	pyrazinamide
sigE	1364925	c.513C>G	synonymous_variant	0.9	pyrazinamide
sigE	1364931	c.519C>T	synonymous_variant	0.85	pyrazinamide
sigE	1364950	c.538_540delGCAinsTG	frameshift_variant&stop_gained	0.85	pyrazinamide	Uncertain significance
sigE	1364956	c.544C>T	synonymous_variant	0.89	pyrazinamide
sigE	1364962	c.550_552delCCTinsGC	frameshift_variant&missense_variant	0.94	pyrazinamide	Uncertain significance
sigE	1364976	c.564T>C	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
sigE	1364979	c.567C>G	synonymous_variant	0.94	pyrazinamide
sigE	1364980	c.568T>C	synonymous_variant	0.94	pyrazinamide
sigE	1364984	p.Ala191Asp	missense_variant	0.94	pyrazinamide
sigE	1364992	p.Pro194Ala	missense_variant	0.95	pyrazinamide
sigE	1365000	c.588G>A	synonymous_variant	0.95	pyrazinamide	Not assoc w R - Interim
sigE	1365003	c.591T>C	synonymous_variant	0.95	pyrazinamide
sigE	1365006	c.594T>C	synonymous_variant	0.95	pyrazinamide
sigE	1365018	c.606G>C	synonymous_variant	0.89	pyrazinamide
sigE	1365042	c.630G>C	synonymous_variant	0.88	pyrazinamide
atpE	1461132	p.Val30Ile	missense_variant	0.65	bedaquiline
atpE	1461137	c.93C>G	synonymous_variant	0.65	bedaquiline
atpE	1461149	c.105T>G	synonymous_variant	0.68	bedaquiline
atpE	1461155	c.111C>G	synonymous_variant	0.68	bedaquiline
atpE	1461159	p.Val39Ile	missense_variant	0.68	bedaquiline	Uncertain significance
atpE	1461167	c.123G>T	synonymous_variant	0.72	bedaquiline
atpE	1461170	c.126A>G	synonymous_variant	0.72	bedaquiline
atpE	1461179	c.135G>C	synonymous_variant	0.72	bedaquiline
atpE	1461182	c.138A>G	synonymous_variant	0.72	bedaquiline
atpE	1461185	c.141G>C	synonymous_variant	0.72	bedaquiline
atpE	1461197	c.153A>C	synonymous_variant	0.68	bedaquiline
atpE	1461219	c.175T>C	synonymous_variant	0.67	bedaquiline
atpE	1461224	c.180T>G	synonymous_variant	0.65	bedaquiline
atpE	1461227	c.183G>A	synonymous_variant	0.62	bedaquiline
atpE	1461230	c.186G>C	synonymous_variant	0.69	bedaquiline
atpE	1461233	c.189A>G	synonymous_variant	0.69	bedaquiline
atpE	1461251	c.207G>C	synonymous_variant	0.64	bedaquiline
atpE	1461254	c.210T>C	synonymous_variant	0.64	bedaquiline
rrs	1471922	n.78delT	non_coding_transcript_exon_variant	0.75	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471925	n.80T>C	non_coding_transcript_exon_variant	0.78	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471931	n.87delA	non_coding_transcript_exon_variant	0.79	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471934	n.89A>G	non_coding_transcript_exon_variant	0.81	streptomycin	Uncertain significance
					kanamycin
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471986	n.141C>T	non_coding_transcript_exon_variant	0.89	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472019	n.174G>A	non_coding_transcript_exon_variant	0.94	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472023	n.178G>T	non_coding_transcript_exon_variant	0.93	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472031	n.186G>C	non_coding_transcript_exon_variant	0.93	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472033	n.188A>C	non_coding_transcript_exon_variant	0.92	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472035	n.190G>T	non_coding_transcript_exon_variant	0.92	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472040	n.195T>G	non_coding_transcript_exon_variant	0.92	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472041	n.196C>T	non_coding_transcript_exon_variant	0.92	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472042	n.197T>G	non_coding_transcript_exon_variant	0.92	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472053	n.211_212delGC	non_coding_transcript_exon_variant	0.91	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472061	n.216A>T	non_coding_transcript_exon_variant	0.91	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	0.91	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472106	n.261G>A	non_coding_transcript_exon_variant	0.91	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Not assoc w R
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	0.91	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472150	n.305T>A	non_coding_transcript_exon_variant	0.91	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472251	n.406G>A	non_coding_transcript_exon_variant	0.84	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Not assoc w R
					amikacin	Not assoc w R
rrs	1472286	n.441C>A	non_coding_transcript_exon_variant	0.56	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472287	n.442C>T	non_coding_transcript_exon_variant	0.53	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472289	n.444T>G	non_coding_transcript_exon_variant	0.53	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472290	n.445C>G	non_coding_transcript_exon_variant	0.53	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472297	n.453_465delGTCCGGGTTCTCT	non_coding_transcript_exon_variant	0.6	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472313	n.468delGinsCA	non_coding_transcript_exon_variant	0.56	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472315	n.470T>G	non_coding_transcript_exon_variant	0.56	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472324	n.479G>C	non_coding_transcript_exon_variant	0.56	streptomycin	Uncertain significance
					kanamycin
					capreomycin
					amikacin
rrs	1472325	n.480G>C	non_coding_transcript_exon_variant	0.56	streptomycin	Uncertain significance
					kanamycin
					capreomycin
					amikacin
rrs	1472327	n.482G>A	non_coding_transcript_exon_variant	0.56	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472328	n.483G>T	non_coding_transcript_exon_variant	0.6	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472337	n.492C>G	non_coding_transcript_exon_variant	0.74	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472380	n.535G>C	non_coding_transcript_exon_variant	0.86	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472446	n.601T>A	non_coding_transcript_exon_variant	0.93	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472452	n.607G>A	non_coding_transcript_exon_variant	0.93	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472464	n.619A>G	non_coding_transcript_exon_variant	0.94	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472846	n.1001C>A	non_coding_transcript_exon_variant	0.93	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472847	n.1002G>C	non_coding_transcript_exon_variant	0.93	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472849	n.1004C>G	non_coding_transcript_exon_variant	0.93	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472850	n.1005T>C	non_coding_transcript_exon_variant	0.94	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472857	n.1012A>G	non_coding_transcript_exon_variant	0.94	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472858	n.1013G>T	non_coding_transcript_exon_variant	0.94	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472860	n.1015C>G	non_coding_transcript_exon_variant	0.94	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472861	n.1016G>T	non_coding_transcript_exon_variant	0.94	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472973	n.1128A>T	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	0.95	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473110	n.1265T>G	non_coding_transcript_exon_variant	0.95	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473111	n.1266A>G	non_coding_transcript_exon_variant	0.95	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473123	n.1278delAinsTC	non_coding_transcript_exon_variant	0.95	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473276	n.1431A>G	non_coding_transcript_exon_variant	0.96	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473290	n.1445C>T	non_coding_transcript_exon_variant	0.95	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473291	n.1446_1447insT	non_coding_transcript_exon_variant	0.95	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473301	n.1456T>C	non_coding_transcript_exon_variant	0.95	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1473699	n.42A>G	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1473699	n.42A>G	non_coding_transcript_exon_variant	0.83	linezolid
rrl	1473717	n.60G>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473717	n.60G>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473746	n.89T>C	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1473746	n.89T>C	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	0.85	linezolid	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1473811	n.154_155insT	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1473811	n.154_155insT	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1473814	n.158delT	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1473814	n.158delT	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1473823	n.166T>C	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1473823	n.166T>C	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1473829	n.172G>T	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1473829	n.172G>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1473830	n.173T>G	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1473830	n.173T>G	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1473831	n.174G>T	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1473831	n.174G>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1473832	n.175C>A	non_coding_transcript_exon_variant	0.85	capreomycin
rrl	1473832	n.175C>A	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	0.85	linezolid	Uncertain significance
rrl	1473887	n.230delTinsAA	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1473887	n.230delTinsAA	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	0.83	linezolid	Uncertain significance
rrl	1473899	n.242A>G	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1473899	n.242A>G	non_coding_transcript_exon_variant	0.83	linezolid	Uncertain significance
rrl	1473916	n.259C>A	non_coding_transcript_exon_variant	0.71	capreomycin	Uncertain significance
rrl	1473916	n.259C>A	non_coding_transcript_exon_variant	0.71	linezolid	Uncertain significance
rrl	1473922	n.265A>G	non_coding_transcript_exon_variant	0.62	capreomycin
rrl	1473922	n.265A>G	non_coding_transcript_exon_variant	0.62	linezolid
rrl	1473923	n.266C>G	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1473923	n.266C>G	non_coding_transcript_exon_variant	0.58	linezolid	Uncertain significance
rrl	1473924	n.267_268insT	non_coding_transcript_exon_variant	0.58	capreomycin
rrl	1473924	n.267_268insT	non_coding_transcript_exon_variant	0.58	linezolid
rrl	1473935	n.278C>T	non_coding_transcript_exon_variant	0.58	capreomycin
rrl	1473935	n.278C>T	non_coding_transcript_exon_variant	0.58	linezolid
rrl	1473937	n.280C>T	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1473937	n.280C>T	non_coding_transcript_exon_variant	0.58	linezolid
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1473943	n.286G>T	non_coding_transcript_exon_variant	0.58	linezolid
rrl	1473945	n.288T>A	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1473945	n.288T>A	non_coding_transcript_exon_variant	0.58	linezolid
rrl	1473946	n.289A>T	non_coding_transcript_exon_variant	0.58	capreomycin	Uncertain significance
rrl	1473946	n.289A>T	non_coding_transcript_exon_variant	0.58	linezolid
rrl	1474016	n.359C>G	non_coding_transcript_exon_variant	0.6	capreomycin
rrl	1474016	n.359C>G	non_coding_transcript_exon_variant	0.6	linezolid
rrl	1474022	n.365G>A	non_coding_transcript_exon_variant	0.64	capreomycin
rrl	1474022	n.365G>A	non_coding_transcript_exon_variant	0.64	linezolid
rrl	1474044	n.387C>T	non_coding_transcript_exon_variant	0.75	capreomycin	Uncertain significance
rrl	1474044	n.387C>T	non_coding_transcript_exon_variant	0.75	linezolid
rrl	1474045	n.388C>T	non_coding_transcript_exon_variant	0.75	capreomycin	Uncertain significance
rrl	1474045	n.388C>T	non_coding_transcript_exon_variant	0.75	linezolid
rrl	1474053	n.396G>A	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1474053	n.396G>A	non_coding_transcript_exon_variant	0.83	linezolid
rrl	1474054	n.397T>C	non_coding_transcript_exon_variant	0.85	capreomycin	Uncertain significance
rrl	1474054	n.397T>C	non_coding_transcript_exon_variant	0.85	linezolid
rrl	1474083	n.426C>T	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1474083	n.426C>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1474091	n.434C>T	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474091	n.434C>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1474093	n.436G>A	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474096	n.439C>T	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474096	n.439C>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1474102	n.446_449delAGTA	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474102	n.446_449delAGTA	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474108	n.451C>G	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474108	n.451C>G	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474110	n.453_454insCGGTG	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474110	n.453_454insCGGTG	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474135	n.478G>A	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1474135	n.478G>A	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474183	n.526T>C	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1474183	n.526T>C	non_coding_transcript_exon_variant	0.83	linezolid	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	0.83	linezolid
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	0.83	linezolid	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1474266	n.609T>C	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1474266	n.609T>C	non_coding_transcript_exon_variant	0.89	linezolid	Uncertain significance
rrl	1474269	n.612C>T	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1474269	n.612C>T	non_coding_transcript_exon_variant	0.89	linezolid	Uncertain significance
rrl	1474288	n.631_632delCCinsTCGACT	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1474288	n.631_632delCCinsTCGACT	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1474292	n.635T>G	non_coding_transcript_exon_variant	0.8	capreomycin
rrl	1474292	n.635T>G	non_coding_transcript_exon_variant	0.8	linezolid
rrl	1474294	n.638_649delCTCTCCGGAGGA	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1474294	n.638_649delCTCTCCGGAGGA	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	0.8	capreomycin	Uncertain significance
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	0.8	linezolid	Uncertain significance
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	0.8	capreomycin
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	0.8	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1474413	n.756_757delACinsTAT	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1474413	n.756_757delACinsTAT	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1474417	n.761_767delCACGCGC	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474417	n.761_767delCACGCGC	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474427	n.770A>C	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474427	n.770A>C	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474430	n.773delCinsTAG	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474430	n.773delCinsTAG	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474432	n.775C>G	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474432	n.775C>G	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474434	n.777_778insTG	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1474434	n.777_778insTG	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1474437	n.781_782delAA	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1474437	n.781_782delAA	non_coding_transcript_exon_variant	0.86	linezolid
rrl	1474446	n.789C>T	non_coding_transcript_exon_variant	0.86	capreomycin	Uncertain significance
rrl	1474446	n.789C>T	non_coding_transcript_exon_variant	0.86	linezolid	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.65	linezolid	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.65	linezolid	Uncertain significance
rrl	1474629	n.972G>A	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474629	n.972G>A	non_coding_transcript_exon_variant	0.65	linezolid
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.62	capreomycin	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.62	linezolid	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.65	linezolid
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.65	linezolid
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.65	linezolid	Uncertain significance
rrl	1474639	n.982G>T	non_coding_transcript_exon_variant	0.65	capreomycin	Uncertain significance
rrl	1474639	n.982G>T	non_coding_transcript_exon_variant	0.65	linezolid
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.68	capreomycin	Uncertain significance
rrl	1474640	n.983C>T	non_coding_transcript_exon_variant	0.68	linezolid
rrl	1474673	n.1016T>C	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1474673	n.1016T>C	non_coding_transcript_exon_variant	0.84	linezolid	Uncertain significance
rrl	1474676	n.1019T>A	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1474676	n.1019T>A	non_coding_transcript_exon_variant	0.84	linezolid	Uncertain significance
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1474677	n.1020A>G	non_coding_transcript_exon_variant	0.84	linezolid	Uncertain significance
rrl	1474710	n.1053T>A	non_coding_transcript_exon_variant	0.86	capreomycin
rrl	1474710	n.1053T>A	non_coding_transcript_exon_variant	0.86	linezolid
rrl	1474711	n.1054G>C	non_coding_transcript_exon_variant	0.86	capreomycin
rrl	1474711	n.1054G>C	non_coding_transcript_exon_variant	0.86	linezolid
rrl	1474712	n.1055G>A	non_coding_transcript_exon_variant	0.86	capreomycin
rrl	1474712	n.1055G>A	non_coding_transcript_exon_variant	0.86	linezolid
rrl	1474713	n.1056T>A	non_coding_transcript_exon_variant	0.86	capreomycin
rrl	1474713	n.1056T>A	non_coding_transcript_exon_variant	0.86	linezolid
rrl	1474716	n.1059_1063delAAAGCinsCCAAGAGT	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1474716	n.1059_1063delAAAGCinsCCAAGAGT	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	0.89	linezolid
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	0.89	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	0.92	linezolid	Uncertain significance
rrl	1474803	n.1146G>A	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1474803	n.1146G>A	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.92	linezolid	Uncertain significance
rrl	1474932	n.1275C>T	non_coding_transcript_exon_variant	0.6	capreomycin	Uncertain significance
rrl	1474932	n.1275C>T	non_coding_transcript_exon_variant	0.6	linezolid	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.76	capreomycin	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.76	linezolid
rrl	1475061	n.1404C>A	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1475061	n.1404C>A	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1475062	n.1405A>T	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1475062	n.1405A>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1475120	n.1463G>T	non_coding_transcript_exon_variant	0.84	capreomycin	Uncertain significance
rrl	1475120	n.1463G>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	0.62	capreomycin	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	0.62	linezolid	Uncertain significance
rrl	1475353	n.1696A>T	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1475353	n.1696A>T	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1475354	n.1697A>G	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1475354	n.1697A>G	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1475363	n.1706C>T	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1475363	n.1706C>T	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1475369	n.1712G>T	non_coding_transcript_exon_variant	0.34	capreomycin
rrl	1475369	n.1712G>T	non_coding_transcript_exon_variant	0.34	linezolid
rrl	1475379	n.1722G>A	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1475379	n.1722G>A	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	0.82	capreomycin	Uncertain significance
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1475381	n.1724G>C	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1475381	n.1724G>C	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1475382	n.1725A>G	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1475382	n.1725A>G	non_coding_transcript_exon_variant	0.82	linezolid
rrl	1475395	n.1738T>C	non_coding_transcript_exon_variant	0.82	capreomycin
rrl	1475395	n.1738T>C	non_coding_transcript_exon_variant	0.82	linezolid	Uncertain significance
rrl	1475396	n.1739C>G	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1475396	n.1739C>G	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1475397	n.1740G>T	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1475397	n.1740G>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1475398	n.1741C>T	non_coding_transcript_exon_variant	0.84	capreomycin
rrl	1475398	n.1741C>T	non_coding_transcript_exon_variant	0.84	linezolid
rrl	1475403	n.1746T>A	non_coding_transcript_exon_variant	0.86	capreomycin
rrl	1475403	n.1746T>A	non_coding_transcript_exon_variant	0.86	linezolid
rrl	1475404	n.1747A>T	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1475404	n.1747A>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1475429	n.1772G>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475429	n.1772G>T	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1475479	n.1822C>G	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475479	n.1822C>G	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475531	n.1874C>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475531	n.1874C>T	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1475603	n.1946G>C	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1475603	n.1946G>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.83	capreomycin	Uncertain significance
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.83	linezolid
rrl	1475612	n.1955G>C	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1475612	n.1955G>C	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475615	n.1958C>G	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1475615	n.1958C>G	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475618	n.1961C>T	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1475618	n.1961C>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475626	n.1969delTinsCC	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1475626	n.1969delTinsCC	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475629	n.1972G>C	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1475629	n.1972G>C	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1475643	n.1986C>G	non_coding_transcript_exon_variant	0.88	capreomycin
rrl	1475643	n.1986C>G	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	0.86	capreomycin
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	0.86	linezolid
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1475753	n.2096C>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1475753	n.2096C>T	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475762	n.2105G>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1475762	n.2105G>T	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475763	n.2106C>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1475763	n.2106C>T	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475764	n.2107A>C	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1475764	n.2107A>C	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475765	n.2108A>G	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1475765	n.2108A>G	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475775	n.2118G>A	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1475775	n.2118G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.9	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1475991	n.2334T>C	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1475991	n.2334T>C	non_coding_transcript_exon_variant	0.89	linezolid
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476033	n.2376T>G	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476033	n.2376T>G	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476035	n.2378G>C	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476035	n.2378G>C	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476046	n.2389G>T	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476046	n.2389G>T	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1476099	n.2442A>G	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476099	n.2442A>G	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1476103	n.2446C>G	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476103	n.2446C>G	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1476105	n.2448G>A	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476105	n.2448G>A	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1476106	n.2449A>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476106	n.2449A>T	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1476110	n.2453G>C	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476110	n.2453G>C	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1476131	n.2474C>T	non_coding_transcript_exon_variant	0.93	linezolid	Uncertain significance
rrl	1476160	n.2503T>C	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476160	n.2503T>C	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1476251	n.2594T>G	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476251	n.2594T>G	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1476256	n.2599A>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476256	n.2599A>T	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	0.94	capreomycin	Not assoc w R
rrl	1476260	n.2603A>G	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1476297	n.2640C>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476297	n.2640C>T	non_coding_transcript_exon_variant	0.95	linezolid	Uncertain significance
rrl	1476299	n.2642C>T	non_coding_transcript_exon_variant	0.96	capreomycin	Uncertain significance
rrl	1476299	n.2642C>T	non_coding_transcript_exon_variant	0.96	linezolid	Uncertain significance
rrl	1476529	n.2872A>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1476529	n.2872A>G	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1476540	n.2883C>T	non_coding_transcript_exon_variant	0.95	capreomycin	Uncertain significance
rrl	1476540	n.2883C>T	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Not assoc w R
rrl	1476584	n.2927C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Not assoc w R
rrl	1476594	n.2937C>T	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	0.92	capreomycin	Uncertain significance
rrl	1476603	n.2946G>A	non_coding_transcript_exon_variant	0.92	linezolid	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	0.91	linezolid	Uncertain significance
rrl	1476664	n.3007T>C	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1476664	n.3007T>C	non_coding_transcript_exon_variant	0.89	linezolid
rrl	1476665	n.3008T>C	non_coding_transcript_exon_variant	0.89	capreomycin	Uncertain significance
rrl	1476665	n.3008T>C	non_coding_transcript_exon_variant	0.89	linezolid
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	0.88	linezolid	Uncertain significance
rrl	1476679	n.3022T>C	non_coding_transcript_exon_variant	0.88	capreomycin	Uncertain significance
rrl	1476679	n.3022T>C	non_coding_transcript_exon_variant	0.88	linezolid
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.87	capreomycin	Uncertain significance
rrl	1476690	n.3033C>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476693	n.3036G>A	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.91	capreomycin
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1476716	n.3059A>C	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476725	n.3068C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476725	n.3068C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476726	n.3069A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476726	n.3069A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476746	n.3089T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476746	n.3089T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476747	n.3090C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476747	n.3090C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476754	n.3097G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476754	n.3097G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	0.94	linezolid
inhA	1673664	c.-538A>C	upstream_gene_variant	0.55	ethionamide
inhA	1673664	c.-538A>C	upstream_gene_variant	0.55	isoniazid
inhA	1673703	c.-499C>T	upstream_gene_variant	0.6	ethionamide
inhA	1673703	c.-499C>T	upstream_gene_variant	0.6	isoniazid
fabG1	1673708	c.270_271delCC	frameshift_variant	0.57	ethionamide
fabG1	1673708	c.270_271delCC	frameshift_variant	0.57	isoniazid
fabG1	1673714	c.275_276insT	frameshift_variant	0.57	ethionamide
fabG1	1673714	c.275_276insT	frameshift_variant	0.57	isoniazid
fabG1	1673717	c.278_279insA	frameshift_variant	0.62	ethionamide
fabG1	1673717	c.278_279insA	frameshift_variant	0.62	isoniazid
inhA	1673724	c.-478A>G	upstream_gene_variant	0.57	ethionamide
inhA	1673724	c.-478A>G	upstream_gene_variant	0.57	isoniazid
inhA	1673730	c.-472C>G	upstream_gene_variant	0.57	ethionamide
inhA	1673730	c.-472C>G	upstream_gene_variant	0.57	isoniazid
inhA	1673745	c.-457G>A	upstream_gene_variant	0.53	ethionamide
inhA	1673745	c.-457G>A	upstream_gene_variant	0.53	isoniazid
inhA	1673748	c.-454A>G	upstream_gene_variant	0.53	ethionamide
inhA	1673748	c.-454A>G	upstream_gene_variant	0.53	isoniazid
fabG1	1673749	p.Lys104Arg	missense_variant	0.53	ethionamide
fabG1	1673749	p.Lys104Arg	missense_variant	0.53	isoniazid
fabG1	1673760	p.Lys107Asn	missense_variant	0.64	ethionamide
fabG1	1673760	p.Lys107Asn	missense_variant	0.64	isoniazid
inhA	1673778	c.-424C>G	upstream_gene_variant	0.64	ethionamide
inhA	1673778	c.-424C>G	upstream_gene_variant	0.64	isoniazid
inhA	1673784	c.-418G>T	upstream_gene_variant	0.7	ethionamide
inhA	1673784	c.-418G>T	upstream_gene_variant	0.7	isoniazid
inhA	1673787	c.-415G>C	upstream_gene_variant	0.82	ethionamide
inhA	1673787	c.-415G>C	upstream_gene_variant	0.82	isoniazid
inhA	1673886	c.-316C>T	upstream_gene_variant	0.69	ethionamide
inhA	1673886	c.-316C>T	upstream_gene_variant	0.69	isoniazid
inhA	1673901	c.-301A>G	upstream_gene_variant	0.79	ethionamide
inhA	1673901	c.-301A>G	upstream_gene_variant	0.79	isoniazid
fabG1	1673905	p.Ser156Ala	missense_variant	0.79	ethionamide
fabG1	1673905	p.Ser156Ala	missense_variant	0.79	isoniazid
inhA	1673913	c.-289C>G	upstream_gene_variant	0.79	ethionamide
inhA	1673913	c.-289C>G	upstream_gene_variant	0.79	isoniazid
inhA	1673916	c.-286A>C	upstream_gene_variant	0.73	ethionamide
inhA	1673916	c.-286A>C	upstream_gene_variant	0.73	isoniazid
fabG1	1673917	p.Val160Leu	missense_variant	0.73	ethionamide
fabG1	1673917	p.Val160Leu	missense_variant	0.73	isoniazid
inhA	1673922	c.-280T>C	upstream_gene_variant	0.73	ethionamide
inhA	1673922	c.-280T>C	upstream_gene_variant	0.73	isoniazid
inhA	1673931	c.-271C>G	upstream_gene_variant	0.71	ethionamide
inhA	1673931	c.-271C>G	upstream_gene_variant	0.71	isoniazid
fabG1	1673941	c.502_504delGCCinsTG	frameshift_variant&missense_variant	0.7	ethionamide
fabG1	1673941	c.502_504delGCCinsTG	frameshift_variant&missense_variant	0.7	isoniazid
inhA	1673952	c.-250G>T	upstream_gene_variant	0.7	ethionamide
inhA	1673952	c.-250G>T	upstream_gene_variant	0.7	isoniazid
inhA	1673955	c.-247G>C	upstream_gene_variant	0.7	ethionamide
inhA	1673955	c.-247G>C	upstream_gene_variant	0.7	isoniazid
inhA	1673961	c.-241A>C	upstream_gene_variant	0.7	ethionamide
inhA	1673961	c.-241A>C	upstream_gene_variant	0.7	isoniazid
fabG1	1673962	p.Asn175Gly	missense_variant	0.7	ethionamide
fabG1	1673962	p.Asn175Gly	missense_variant	0.7	isoniazid
inhA	1673967	c.-235G>C	upstream_gene_variant	0.73	ethionamide
inhA	1673967	c.-235G>C	upstream_gene_variant	0.73	isoniazid
inhA	1673973	c.-229G>C	upstream_gene_variant	0.73	ethionamide
inhA	1673973	c.-229G>C	upstream_gene_variant	0.73	isoniazid	Uncertain significance
inhA	1673976	c.-226T>C	upstream_gene_variant	0.79	ethionamide
inhA	1673976	c.-226T>C	upstream_gene_variant	0.79	isoniazid
fabG1	1674006	p.Asp189Glu	missense_variant	0.85	ethionamide
fabG1	1674006	p.Asp189Glu	missense_variant	0.85	isoniazid
inhA	1674024	c.-178T>C	upstream_gene_variant	0.76	ethionamide
inhA	1674024	c.-178T>C	upstream_gene_variant	0.76	isoniazid
inhA	1674549	c.348G>C	synonymous_variant	0.55	ethionamide
inhA	1674549	c.348G>C	synonymous_variant	0.55	isoniazid
inhA	1674550	p.Ser117Ala	missense_variant	0.55	ethionamide
inhA	1674550	p.Ser117Ala	missense_variant	0.55	isoniazid
inhA	1674573	c.372G>C	synonymous_variant	0.71	ethionamide
inhA	1674573	c.372G>C	synonymous_variant	0.71	isoniazid
inhA	1674576	c.375T>C	synonymous_variant	0.71	ethionamide
inhA	1674576	c.375T>C	synonymous_variant	0.71	isoniazid
inhA	1674579	c.378G>C	synonymous_variant	0.71	ethionamide
inhA	1674579	c.378G>C	synonymous_variant	0.71	isoniazid
inhA	1674585	c.384T>C	synonymous_variant	0.71	ethionamide
inhA	1674585	c.384T>C	synonymous_variant	0.71	isoniazid
inhA	1674589	p.Met130Leu	missense_variant	0.71	ethionamide
inhA	1674589	p.Met130Leu	missense_variant	0.71	isoniazid
inhA	1674600	c.399G>C	synonymous_variant	0.62	ethionamide
inhA	1674600	c.399G>C	synonymous_variant	0.62	isoniazid
inhA	1674601	p.Leu134Thr	missense_variant	0.6	ethionamide
inhA	1674601	p.Leu134Thr	missense_variant	0.6	isoniazid
inhA	1674619	p.Pro140Glu	missense_variant	0.56	ethionamide
inhA	1674619	p.Pro140Glu	missense_variant	0.56	isoniazid
inhA	1674624	c.423A>C	synonymous_variant	0.56	ethionamide
inhA	1674624	c.423A>C	synonymous_variant	0.56	isoniazid
inhA	1674627	c.426T>C	synonymous_variant	0.56	ethionamide
inhA	1674627	c.426T>C	synonymous_variant	0.56	isoniazid
inhA	1674628	c.427_428delTCinsAG	synonymous_variant	0.56	ethionamide
inhA	1674628	c.427_428delTCinsAG	synonymous_variant	0.56	isoniazid
inhA	1674651	c.450C>T	synonymous_variant	0.65	ethionamide
inhA	1674651	c.450C>T	synonymous_variant	0.65	isoniazid
inhA	1674656	p.Ser152Thr	missense_variant	0.68	ethionamide
inhA	1674656	p.Ser152Thr	missense_variant	0.68	isoniazid
inhA	1674660	c.459G>C	synonymous_variant	0.68	ethionamide
inhA	1674660	c.459G>C	synonymous_variant	0.68	isoniazid
inhA	1674663	c.462G>C	synonymous_variant	0.68	ethionamide
inhA	1674663	c.462G>C	synonymous_variant	0.68	isoniazid
inhA	1674672	c.471C>A	synonymous_variant	0.67	ethionamide
inhA	1674672	c.471C>A	synonymous_variant	0.67	isoniazid
inhA	1674690	c.489C>G	synonymous_variant	0.74	ethionamide
inhA	1674690	c.489C>G	synonymous_variant	0.74	isoniazid
inhA	1674702	c.501G>T	synonymous_variant	0.62	ethionamide
inhA	1674702	c.501G>T	synonymous_variant	0.62	isoniazid
inhA	1674703	c.502_504delTTGinsCC	frameshift_variant&missense_variant	0.58	ethionamide
inhA	1674703	c.502_504delTTGinsCC	frameshift_variant&missense_variant	0.58	isoniazid
inhA	1674718	c.517A>C	synonymous_variant	0.54	ethionamide
inhA	1674718	c.517A>C	synonymous_variant	0.54	isoniazid
inhA	1674729	c.528G>T	synonymous_variant	0.54	ethionamide
inhA	1674729	c.528G>T	synonymous_variant	0.54	isoniazid
inhA	1674742	p.Lys181Ala	missense_variant	0.54	ethionamide
inhA	1674742	p.Lys181Ala	missense_variant	0.54	isoniazid
inhA	1674745	p.Tyr182Ala	missense_variant	0.54	ethionamide
inhA	1674745	p.Tyr182Ala	missense_variant	0.54	isoniazid
inhA	1674753	c.552G>C	synonymous_variant	0.62	ethionamide
inhA	1674753	c.552G>C	synonymous_variant	0.62	isoniazid
inhA	1674774	c.573A>C	synonymous_variant	0.67	ethionamide
inhA	1674774	c.573A>C	synonymous_variant	0.67	isoniazid
inhA	1674777	c.576C>G	synonymous_variant	0.67	ethionamide
inhA	1674777	c.576C>G	synonymous_variant	0.67	isoniazid
inhA	1674780	c.579T>G	synonymous_variant	0.64	ethionamide
inhA	1674780	c.579T>G	synonymous_variant	0.64	isoniazid
rpsA	1833547	c.6G>A	synonymous_variant	0.67	pyrazinamide
rpsA	1833554	p.Thr5Ser	missense_variant	0.75	pyrazinamide
rpsA	1833589	c.48A>C	synonymous_variant	0.81	pyrazinamide
rpsA	1833595	c.54T>G	synonymous_variant	0.81	pyrazinamide
rpsA	1833596	p.Ser19Ala	missense_variant	0.81	pyrazinamide
rpsA	1833616	c.75A>C	synonymous_variant	0.85	pyrazinamide
rpsA	1833619	c.78A>C	synonymous_variant	0.85	pyrazinamide
rpsA	1833628	c.87G>C	synonymous_variant	0.85	pyrazinamide
rpsA	1833634	c.93G>A	synonymous_variant	0.86	pyrazinamide
rpsA	1833661	c.120A>G	synonymous_variant	0.85	pyrazinamide
rpsA	1833664	c.123C>A	synonymous_variant	0.85	pyrazinamide
rpsA	1833676	c.135A>G	synonymous_variant	0.85	pyrazinamide
rpsA	1833679	c.138G>T	synonymous_variant	0.85	pyrazinamide
rpsA	1833685	c.144G>T	synonymous_variant	0.85	pyrazinamide
rpsA	1833694	c.153G>C	synonymous_variant	0.81	pyrazinamide
rpsA	1833697	c.156C>G	synonymous_variant	0.82	pyrazinamide
rpsA	1833703	c.162C>T	synonymous_variant	0.82	pyrazinamide	Not assoc w R - Interim
rpsA	1833724	c.183C>T	synonymous_variant	0.8	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	0.79	pyrazinamide
rpsA	1833730	c.189C>T	synonymous_variant	0.79	pyrazinamide
rpsA	1833733	c.192C>T	synonymous_variant	0.81	pyrazinamide
rpsA	1833734	p.Ala65Ser	missense_variant	0.84	pyrazinamide
rpsA	1833745	c.204G>C	synonymous_variant	0.83	pyrazinamide
rpsA	1833760	c.219C>T	synonymous_variant	0.81	pyrazinamide	Not assoc w R - Interim
rpsA	1833787	c.246C>G	synonymous_variant	0.81	pyrazinamide
rpsA	1833790	c.249T>C	synonymous_variant	0.82	pyrazinamide
rpsA	1833793	c.252C>T	synonymous_variant	0.82	pyrazinamide
rpsA	1833802	c.261A>G	synonymous_variant	0.83	pyrazinamide
rpsA	1833811	c.270G>T	synonymous_variant	0.84	pyrazinamide
rpsA	1833829	c.288A>G	synonymous_variant	0.84	pyrazinamide
rpsA	1833832	c.291G>A	synonymous_variant	0.84	pyrazinamide
rpsA	1833838	c.297G>C	synonymous_variant	0.83	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	0.83	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	0.83	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	0.83	pyrazinamide
rpsA	1833862	c.321G>T	synonymous_variant	0.82	pyrazinamide
rpsA	1833894	p.Ala118Glu	missense_variant	0.88	pyrazinamide
rpsA	1833904	c.363G>A	synonymous_variant	0.94	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	0.93	pyrazinamide
rpsA	1833949	c.408T>C	synonymous_variant	0.93	pyrazinamide
rpsA	1833970	c.429G>T	synonymous_variant	0.89	pyrazinamide
rpsA	1833976	c.435C>T	synonymous_variant	0.86	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	0.87	pyrazinamide
rpsA	1833991	c.450C>A	synonymous_variant	0.9	pyrazinamide
rpsA	1834000	c.459G>C	synonymous_variant	0.9	pyrazinamide
rpsA	1834009	c.468C>T	synonymous_variant	0.89	pyrazinamide
rpsA	1834012	c.471G>T	synonymous_variant	0.86	pyrazinamide
rpsA	1834015	c.474G>C	synonymous_variant	0.86	pyrazinamide
rpsA	1834021	c.480C>T	synonymous_variant	0.86	pyrazinamide
rpsA	1834030	c.489C>G	synonymous_variant	0.86	pyrazinamide
rpsA	1834097	c.556_557delTCinsAG	synonymous_variant	0.86	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834150	c.609G>C	synonymous_variant	0.85	pyrazinamide
rpsA	1834153	c.612T>C	synonymous_variant	0.85	pyrazinamide
rpsA	1834154	c.613_615delAACinsCG	frameshift_variant&missense_variant	0.85	pyrazinamide	Uncertain significance
rpsA	1834157	c.616T>C	synonymous_variant	0.81	pyrazinamide
rpsA	1834162	c.621A>G	synonymous_variant	0.81	pyrazinamide	Not assoc w R - Interim
rpsA	1834165	c.624A>G	synonymous_variant	0.85	pyrazinamide
rpsA	1834168	c.627C>T	synonymous_variant	0.85	pyrazinamide	Not assoc w R - Interim
rpsA	1834169	p.Thr210Ala	missense_variant	0.85	pyrazinamide	Uncertain significance
rpsA	1834177	c.636A>C	synonymous_variant	0.91	pyrazinamide	Not assoc w R - Interim
rpsA	1834189	c.648G>C	synonymous_variant	0.88	pyrazinamide
rpsA	1834213	c.672G>C	synonymous_variant	0.91	pyrazinamide
rpsA	1834234	c.693G>C	synonymous_variant	0.88	pyrazinamide
rpsA	1834240	c.699T>C	synonymous_variant	0.87	pyrazinamide
rpsA	1834246	c.705G>C	synonymous_variant	0.87	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	0.87	pyrazinamide
rpsA	1834252	c.711C>G	synonymous_variant	0.87	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	0.87	pyrazinamide	Not assoc w R - Interim
rpsA	1834264	c.723G>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834279	c.738C>T	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
rpsA	1834297	c.756C>T	synonymous_variant	0.98	pyrazinamide
rpsA	1834303	c.762T>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834345	c.804C>T	synonymous_variant	0.94	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
rpsA	1834361	c.820T>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834366	c.825A>G	synonymous_variant	0.88	pyrazinamide	Not assoc w R - Interim
rpsA	1834396	c.855G>C	synonymous_variant	0.91	pyrazinamide
rpsA	1834411	c.870T>C	synonymous_variant	0.9	pyrazinamide
rpsA	1834423	c.882G>T	synonymous_variant	0.9	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	0.84	pyrazinamide
rpsA	1834456	c.915T>G	synonymous_variant	0.84	pyrazinamide
rpsA	1834468	c.927A>G	synonymous_variant	0.86	pyrazinamide
rpsA	1834489	c.948T>C	synonymous_variant	0.91	pyrazinamide
rpsA	1834513	c.972C>G	synonymous_variant	0.92	pyrazinamide
rpsA	1834520	p.Ala327Ser	missense_variant	0.94	pyrazinamide
rpsA	1834528	c.987T>C	synonymous_variant	0.94	pyrazinamide
rpsA	1834540	c.999G>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834543	c.1002C>G	synonymous_variant	0.89	pyrazinamide
rpsA	1834546	c.1005T>C	synonymous_variant	0.92	pyrazinamide
rpsA	1834554	c.1014_1015delTG	frameshift_variant	0.92	pyrazinamide	Uncertain significance
rpsA	1834558	c.1017_1018insAG	frameshift_variant	0.88	pyrazinamide	Uncertain significance
rpsA	1834606	c.1065C>T	synonymous_variant	0.89	pyrazinamide
rpsA	1834609	c.1068T>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834619	c.1078T>C	synonymous_variant	0.87	pyrazinamide
rpsA	1834622	c.1081_1083delTCGinsAGC	synonymous_variant	0.86	pyrazinamide
rpsA	1834633	c.1092A>G	synonymous_variant	0.86	pyrazinamide
rpsA	1834639	c.1098T>C	synonymous_variant	0.86	pyrazinamide
rpsA	1834666	c.1125G>C	synonymous_variant	0.88	pyrazinamide
rpsA	1834667	p.Ala376Ser	missense_variant	0.88	pyrazinamide
rpsA	1834690	c.1149T>C	synonymous_variant	0.86	pyrazinamide
rpsA	1834732	c.1191T>C	synonymous_variant	0.86	pyrazinamide
rpsA	1834738	c.1197A>G	synonymous_variant	0.86	pyrazinamide
rpsA	1834753	c.1212T>C	synonymous_variant	0.88	pyrazinamide
rpsA	1834756	c.1215G>A	synonymous_variant	0.88	pyrazinamide
rpsA	1834759	c.1218A>C	synonymous_variant	0.83	pyrazinamide
rpsA	1834765	p.Glu408Asp	missense_variant	0.83	pyrazinamide
rpsA	1834774	c.1233C>G	synonymous_variant	0.83	pyrazinamide
rpsA	1834776	p.Ala412Glu	missense_variant	0.83	pyrazinamide
rpsA	1834780	c.1239A>G	synonymous_variant	0.83	pyrazinamide
rpsA	1834786	c.1245A>G	synonymous_variant	0.79	pyrazinamide
rpsA	1834789	c.1248T>C	synonymous_variant	0.79	pyrazinamide
rpsA	1834792	c.1251G>C	synonymous_variant	0.79	pyrazinamide
rpsA	1834829	c.1288_1290delGCGinsAC	frameshift_variant&missense_variant	0.69	pyrazinamide	Uncertain significance
tsnR	1853361	c.-245T>C	upstream_gene_variant	0.68	linezolid
tsnR	1853370	c.-236_-234delGCAinsTG	upstream_gene_variant	0.72	linezolid
tsnR	1853375	c.-231G>T	upstream_gene_variant	0.67	linezolid
tsnR	1853384	c.-222G>C	upstream_gene_variant	0.65	linezolid
tsnR	1853387	c.-219T>G	upstream_gene_variant	0.65	linezolid
tsnR	1853390	c.-216G>C	upstream_gene_variant	0.65	linezolid
tsnR	1853394	c.-212_-211delCTinsGC	upstream_gene_variant	0.62	linezolid
tsnR	1853417	c.-189G>C	upstream_gene_variant	0.59	linezolid
tsnR	1853420	c.-186T>G	upstream_gene_variant	0.59	linezolid
tsnR	1853429	c.-177G>C	upstream_gene_variant	0.61	linezolid
tsnR	1853432	c.-174G>C	upstream_gene_variant	0.61	linezolid
tsnR	1853441	c.-165C>G	upstream_gene_variant	0.55	linezolid
ndh	2102270	p.Thr258Ser	missense_variant	0.9	ethionamide
					delamanid
					isoniazid	Uncertain significance
katG	2155680	c.432G>A	synonymous_variant	0.8	isoniazid
katG	2155691	c.421T>C	synonymous_variant	0.8	isoniazid
katG	2155696	p.Ala139Val	missense_variant	0.83	isoniazid
katG	2155716	c.396T>G	synonymous_variant	0.91	isoniazid
katG	2155722	c.390G>C	synonymous_variant	0.91	isoniazid
katG	2155728	c.384G>C	synonymous_variant	0.91	isoniazid
katG	2155742	p.Gly124Arg	missense_variant	0.83	isoniazid
katG	2155747	p.Ala122Gly	missense_variant	0.77	isoniazid
katG	2155749	c.363C>T	synonymous_variant	0.77	isoniazid	Not assoc w R - Interim
katG	2155752	c.360C>T	synonymous_variant	0.77	isoniazid
katG	2155769	p.Ile115Val	missense_variant	0.77	isoniazid
katG	2155770	c.342C>G	synonymous_variant	0.77	isoniazid
katG	2155782	c.330C>A	synonymous_variant	0.75	isoniazid
katG	2155785	c.327T>C	synonymous_variant	0.73	isoniazid
kasA	2517941	c.-174C>G	upstream_gene_variant	0.59	isoniazid
kasA	2517959	c.-156C>T	upstream_gene_variant	0.5	isoniazid
kasA	2517962	c.-153C>G	upstream_gene_variant	0.47	isoniazid
kasA	2517968	c.-147T>C	upstream_gene_variant	0.47	isoniazid
kasA	2517974	c.-141T>C	upstream_gene_variant	0.47	isoniazid
kasA	2517980	c.-135C>T	upstream_gene_variant	0.47	isoniazid
kasA	2518726	c.612G>A	synonymous_variant	0.57	isoniazid
kasA	2518732	c.618C>G	synonymous_variant	0.6	isoniazid
kasA	2518747	c.633C>G	synonymous_variant	0.71	isoniazid
kasA	2518756	c.642G>C	synonymous_variant	0.71	isoniazid
kasA	2518780	p.Glu222Asp	missense_variant	0.61	isoniazid
kasA	2518783	c.669T>C	synonymous_variant	0.59	isoniazid
kasA	2518785	p.Glu224Ala	missense_variant	0.56	isoniazid
kasA	2518787	c.673_675delCGGinsGT	frameshift_variant&missense_variant	0.59	isoniazid
kasA	2518792	c.678C>G	synonymous_variant	0.69	isoniazid
kasA	2518795	c.681C>T	synonymous_variant	0.69	isoniazid
kasA	2518813	c.699C>T	synonymous_variant	0.73	isoniazid
kasA	2518816	c.702C>T	synonymous_variant	0.71	isoniazid
kasA	2518825	c.711T>C	synonymous_variant	0.73	isoniazid
kasA	2518843	c.729T>C	synonymous_variant	0.6	isoniazid
kasA	2518847	p.Leu245Met	missense_variant	0.6	isoniazid
kasA	2518853	p.Leu247Ile	missense_variant	0.57	isoniazid
kasA	2518864	c.750G>C	synonymous_variant	0.5	isoniazid
folC	2747029	c.570G>C	synonymous_variant	0.7	para-aminosalicylic_acid
folC	2747032	c.567A>C	synonymous_variant	0.7	para-aminosalicylic_acid
folC	2747040	p.Ile187Val	missense_variant	0.7	para-aminosalicylic_acid
folC	2747041	c.558G>C	synonymous_variant	0.7	para-aminosalicylic_acid
folC	2747062	c.537A>C	synonymous_variant	0.7	para-aminosalicylic_acid
folC	2747065	c.534C>A	synonymous_variant	0.6	para-aminosalicylic_acid
folC	2747071	c.528C>G	synonymous_variant	0.7	para-aminosalicylic_acid
folC	2747074	c.525G>C	synonymous_variant	0.7	para-aminosalicylic_acid
folC	2747110	c.489T>C	synonymous_variant	0.6	para-aminosalicylic_acid
folC	2747116	c.483G>C	synonymous_variant	0.55	para-aminosalicylic_acid
folC	2747134	c.463_465delCTCinsTG	frameshift_variant&synonymous_variant	0.55	para-aminosalicylic_acid
folC	2747137	c.462G>C	synonymous_variant	0.6	para-aminosalicylic_acid
Rv2477c	2782948	c.1095A>G	synonymous_variant	0.73	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782969	c.1074A>C	synonymous_variant	0.73	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782972	c.1071G>C	synonymous_variant	0.73	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782981	c.1062G>T	synonymous_variant	0.73	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782984	c.1059T>C	synonymous_variant	0.67	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783002	c.1041T>C	synonymous_variant	0.73	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783008	c.1035C>G	synonymous_variant	0.73	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783013	c.1030T>C	synonymous_variant	0.69	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783014	p.Ser343Thr	missense_variant	0.69	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783020	c.1023G>C	synonymous_variant	0.69	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783440	c.603T>C	synonymous_variant	0.76	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783446	c.597A>G	synonymous_variant	0.76	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783456	p.Gln196Leu	missense_variant	0.73	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783461	c.582T>C	synonymous_variant	0.67	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783464	c.579A>G	synonymous_variant	0.67	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783467	c.576G>C	synonymous_variant	0.67	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783473	c.570A>C	synonymous_variant	0.67	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783485	c.558G>C	synonymous_variant	0.64	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2752c	3065022	c.1170G>C	synonymous_variant	0.65	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065058	c.1134C>G	synonymous_variant	0.77	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065061	c.1131C>T	synonymous_variant	0.81	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065064	c.1128G>C	synonymous_variant	0.81	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065070	c.1122C>T	synonymous_variant	0.81	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065079	c.1113T>C	synonymous_variant	0.74	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065082	c.1110G>T	synonymous_variant	0.74	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065085	c.1105_1107delAGGinsCC	frameshift_variant&missense_variant	0.74	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065088	c.1104A>G	synonymous_variant	0.74	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065109	c.1081_1083delAGAinsCC	frameshift_variant&missense_variant	0.7	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065126	p.Ser356Ala	missense_variant	0.72	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065130	c.1062A>G	synonymous_variant	0.72	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065133	c.1059T>C	synonymous_variant	0.72	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065142	c.1050A>G	synonymous_variant	0.77	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065146	p.Phe349Tyr	missense_variant	0.75	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065154	c.1038G>A	synonymous_variant	0.74	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065160	c.1032C>T	synonymous_variant	0.72	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065166	c.1026C>G	synonymous_variant	0.7	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065174	c.1018C>T	synonymous_variant	0.67	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065181	c.1011G>C	synonymous_variant	0.58	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065898	c.294C>G	synonymous_variant	0.53	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065901	c.291A>C	synonymous_variant	0.53	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065907	c.285G>A	synonymous_variant	0.53	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065916	p.Phe92Tyr	missense_variant	0.57	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065925	c.267G>C	synonymous_variant	0.53	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065947	p.Gly82Ala	missense_variant	0.5	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065955	c.235_237delTTGinsGC	frameshift_variant&missense_variant	0.5	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065958	c.234G>C	synonymous_variant	0.5	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065961	c.231G>C	synonymous_variant	0.54	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065967	c.225G>A	synonymous_variant	0.5	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065972	p.Ile74Val	missense_variant	0.54	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065976	p.Asp72Glu	missense_variant	0.5	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065979	c.213T>C	synonymous_variant	0.54	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065982	c.210G>T	synonymous_variant	0.54	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065988	c.204A>G	synonymous_variant	0.54	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065994	c.198T>C	synonymous_variant	0.54	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065997	c.195C>G	synonymous_variant	0.54	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3066002	p.Met64Leu	missense_variant	0.5	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
thyX	3067376	c.570G>C	synonymous_variant	0.4	para-aminosalicylic_acid
thyX	3067406	c.540A>G	synonymous_variant	0.55	para-aminosalicylic_acid
thyX	3067788	p.Lys53Arg	missense_variant	0.54	para-aminosalicylic_acid
thyX	3067808	c.138C>T	synonymous_variant	0.58	para-aminosalicylic_acid
thyX	3067814	c.132T>C	synonymous_variant	0.58	para-aminosalicylic_acid
thyX	3067817	c.129C>T	synonymous_variant	0.58	para-aminosalicylic_acid
thyX	3067820	c.126C>G	synonymous_variant	0.58	para-aminosalicylic_acid
thyX	3067825	c.121C>A	synonymous_variant	0.58	para-aminosalicylic_acid
thyX	3067839	p.Val36Thr	missense_variant	0.64	para-aminosalicylic_acid
thyX	3067841	c.105G>C	synonymous_variant	0.64	para-aminosalicylic_acid
thyX	3067847	c.99C>T	synonymous_variant	0.64	para-aminosalicylic_acid
thyX	3067853	c.93C>T	synonymous_variant	0.58	para-aminosalicylic_acid
thyX	3067862	c.84C>T	synonymous_variant	0.7	para-aminosalicylic_acid
thyX	3067869	p.Thr26Ser	missense_variant	0.7	para-aminosalicylic_acid
thyX	3067874	c.72C>G	synonymous_variant	0.7	para-aminosalicylic_acid
thyX	3067883	c.63C>T	synonymous_variant	0.7	para-aminosalicylic_acid
thyX	3067886	c.60A>G	synonymous_variant	0.7	para-aminosalicylic_acid
thyX	3067889	c.57C>G	synonymous_variant	0.7	para-aminosalicylic_acid
thyX	3067893	p.Leu18Gln	missense_variant	0.7	para-aminosalicylic_acid
thyX	3067898	p.Asp16Glu	missense_variant	0.7	para-aminosalicylic_acid
thyX	3067901	c.45C>G	synonymous_variant	0.7	para-aminosalicylic_acid
thyX	3067916	c.30A>G	synonymous_variant	0.7	para-aminosalicylic_acid
thyA	3073839	c.633T>C	synonymous_variant	0.9	para-aminosalicylic_acid
thyA	3073845	c.627C>T	synonymous_variant	0.92	para-aminosalicylic_acid
thyA	3073860	c.612C>T	synonymous_variant	0.92	para-aminosalicylic_acid
thyA	3073863	c.609T>C	synonymous_variant	0.92	para-aminosalicylic_acid
thyA	3073874	p.Ile200Val	missense_variant	0.86	para-aminosalicylic_acid
thyA	3073886	c.585_586insAT	frameshift_variant	0.8	para-aminosalicylic_acid
thyA	3073902	c.570C>G	synonymous_variant	0.8	para-aminosalicylic_acid
thyA	3073920	c.550_552delCTCinsTG	frameshift_variant&synonymous_variant	0.8	para-aminosalicylic_acid
thyA	3073925	c.547T>C	synonymous_variant	0.8	para-aminosalicylic_acid
thyA	3073926	c.546G>C	synonymous_variant	0.8	para-aminosalicylic_acid
thyA	3073929	c.543T>C	synonymous_variant	0.8	para-aminosalicylic_acid
thyA	3073953	c.519T>C	synonymous_variant	0.75	para-aminosalicylic_acid
thyA	3073959	c.513T>C	synonymous_variant	0.8	para-aminosalicylic_acid
thyA	3073962	c.510G>C	synonymous_variant	0.79	para-aminosalicylic_acid
thyA	3073971	c.501C>T	synonymous_variant	0.73	para-aminosalicylic_acid
lpqB	3624584	c.327G>C	synonymous_variant	0.53	bedaquiline
lpqB	3624584	c.327G>C	synonymous_variant	0.53	rifampicin
lpqB	3624591	p.Thr107Ser	missense_variant	0.53	bedaquiline
lpqB	3624591	p.Thr107Ser	missense_variant	0.53	rifampicin
lpqB	3624603	p.Lys103Arg	missense_variant	0.56	bedaquiline
lpqB	3624603	p.Lys103Arg	missense_variant	0.56	rifampicin
lpqB	3624605	p.Glu102Asp	missense_variant	0.56	bedaquiline
lpqB	3624605	p.Glu102Asp	missense_variant	0.56	rifampicin	Uncertain significance
lpqB	3624614	c.297A>C	synonymous_variant	0.62	bedaquiline
lpqB	3624614	c.297A>C	synonymous_variant	0.62	rifampicin
lpqB	3624617	c.294C>T	synonymous_variant	0.65	bedaquiline
lpqB	3624617	c.294C>T	synonymous_variant	0.65	rifampicin
lpqB	3624636	p.His92Arg	missense_variant	0.73	bedaquiline
lpqB	3624636	p.His92Arg	missense_variant	0.73	rifampicin	Uncertain significance
lpqB	3624643	p.Ile90Leu	missense_variant	0.73	bedaquiline
lpqB	3624643	p.Ile90Leu	missense_variant	0.73	rifampicin
lpqB	3624646	c.265T>C	synonymous_variant	0.73	bedaquiline
lpqB	3624646	c.265T>C	synonymous_variant	0.73	rifampicin
lpqB	3624649	c.262T>C	synonymous_variant	0.79	bedaquiline
lpqB	3624649	c.262T>C	synonymous_variant	0.79	rifampicin
lpqB	3624650	c.261G>A	synonymous_variant	0.79	bedaquiline
lpqB	3624650	c.261G>A	synonymous_variant	0.79	rifampicin
lpqB	3624656	c.255C>T	synonymous_variant	0.79	bedaquiline
lpqB	3624656	c.255C>T	synonymous_variant	0.79	rifampicin
lpqB	3624673	p.Ala80Ser	missense_variant	0.73	bedaquiline
lpqB	3624673	p.Ala80Ser	missense_variant	0.73	rifampicin
lpqB	3624675	p.Asn79Ser	missense_variant	0.73	bedaquiline
lpqB	3624675	p.Asn79Ser	missense_variant	0.73	rifampicin
lpqB	3624680	c.231T>G	synonymous_variant	0.75	bedaquiline
lpqB	3624680	c.231T>G	synonymous_variant	0.75	rifampicin
lpqB	3624701	c.210T>G	synonymous_variant	0.75	bedaquiline
lpqB	3624701	c.210T>G	synonymous_variant	0.75	rifampicin
lpqB	3624704	c.207G>C	synonymous_variant	0.75	bedaquiline
lpqB	3624704	c.207G>C	synonymous_variant	0.75	rifampicin
lpqB	3624719	c.192C>T	synonymous_variant	0.85	bedaquiline
lpqB	3624719	c.192C>T	synonymous_variant	0.85	rifampicin
lpqB	3624725	c.186G>T	synonymous_variant	0.8	bedaquiline
lpqB	3624725	c.186G>T	synonymous_variant	0.8	rifampicin
lpqB	3625174	c.-264C>T	upstream_gene_variant	0.71	bedaquiline
lpqB	3625174	c.-264C>T	upstream_gene_variant	0.71	rifampicin
lpqB	3625183	c.-273G>C	upstream_gene_variant	0.71	bedaquiline
lpqB	3625183	c.-273G>C	upstream_gene_variant	0.71	rifampicin
lpqB	3625186	c.-276T>G	upstream_gene_variant	0.71	bedaquiline
lpqB	3625186	c.-276T>G	upstream_gene_variant	0.71	rifampicin
lpqB	3625195	c.-285A>G	upstream_gene_variant	0.71	bedaquiline
lpqB	3625195	c.-285A>G	upstream_gene_variant	0.71	rifampicin
lpqB	3625198	c.-288C>G	upstream_gene_variant	0.71	bedaquiline
lpqB	3625198	c.-288C>G	upstream_gene_variant	0.71	rifampicin
lpqB	3625201	c.-291T>C	upstream_gene_variant	0.71	bedaquiline
lpqB	3625201	c.-291T>C	upstream_gene_variant	0.71	rifampicin
lpqB	3625204	c.-294G>C	upstream_gene_variant	0.71	bedaquiline
lpqB	3625204	c.-294G>C	upstream_gene_variant	0.71	rifampicin
lpqB	3625207	c.-297C>G	upstream_gene_variant	0.73	bedaquiline
lpqB	3625207	c.-297C>G	upstream_gene_variant	0.73	rifampicin
mtrB	3625222	c.1392T>C	synonymous_variant	0.65	bedaquiline
mtrB	3625222	c.1392T>C	synonymous_variant	0.65	rifampicin	Not assoc w R - Interim
lpqB	3625243	c.-333T>G	upstream_gene_variant	0.72	bedaquiline
lpqB	3625243	c.-333T>G	upstream_gene_variant	0.72	rifampicin
mtrB	3625252	c.1362G>C	synonymous_variant	0.65	bedaquiline
mtrB	3625252	c.1362G>C	synonymous_variant	0.65	rifampicin	Not assoc w R - Interim
lpqB	3625255	c.-345T>C	upstream_gene_variant	0.63	bedaquiline
lpqB	3625255	c.-345T>C	upstream_gene_variant	0.63	rifampicin
lpqB	3625258	c.-348G>T	upstream_gene_variant	0.63	bedaquiline
lpqB	3625258	c.-348G>T	upstream_gene_variant	0.63	rifampicin
mtrB	3625264	c.1350C>T	synonymous_variant	0.63	bedaquiline	Not assoc w R - Interim
mtrB	3625264	c.1350C>T	synonymous_variant	0.63	rifampicin	Not assoc w R - Interim
mtrB	3625267	c.1347T>C	synonymous_variant	0.67	bedaquiline
mtrB	3625267	c.1347T>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
lpqB	3625279	c.-369C>G	upstream_gene_variant	0.73	bedaquiline
lpqB	3625279	c.-369C>G	upstream_gene_variant	0.73	rifampicin
lpqB	3625285	c.-375G>C	upstream_gene_variant	0.73	bedaquiline
lpqB	3625285	c.-375G>C	upstream_gene_variant	0.73	rifampicin
lpqB	3625291	c.-381A>G	upstream_gene_variant	0.73	bedaquiline
lpqB	3625291	c.-381A>G	upstream_gene_variant	0.73	rifampicin
lpqB	3625300	c.-390C>G	upstream_gene_variant	0.59	bedaquiline
lpqB	3625300	c.-390C>G	upstream_gene_variant	0.59	rifampicin
lpqB	3625312	c.-402G>C	upstream_gene_variant	0.59	bedaquiline
lpqB	3625312	c.-402G>C	upstream_gene_variant	0.59	rifampicin
mtrB	3625321	c.1293A>G	synonymous_variant	0.56	bedaquiline	Not assoc w R - Interim
mtrB	3625321	c.1293A>G	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
mtrB	3625325	p.His430Arg	missense_variant	0.5	bedaquiline
mtrB	3625325	p.His430Arg	missense_variant	0.5	rifampicin
lpqB	3625330	c.-420C>A	upstream_gene_variant	0.5	bedaquiline
lpqB	3625330	c.-420C>A	upstream_gene_variant	0.5	rifampicin
lpqB	3625336	c.-426C>T	upstream_gene_variant	0.5	bedaquiline
lpqB	3625336	c.-426C>T	upstream_gene_variant	0.5	rifampicin
lpqB	3625345	c.-435T>C	upstream_gene_variant	0.5	bedaquiline
lpqB	3625345	c.-435T>C	upstream_gene_variant	0.5	rifampicin
mtrB	3625351	c.1263T>C	synonymous_variant	0.5	bedaquiline
mtrB	3625351	c.1263T>C	synonymous_variant	0.5	rifampicin	Not assoc w R - Interim
lpqB	3625356	c.-446C>T	upstream_gene_variant	0.46	bedaquiline
lpqB	3625356	c.-446C>T	upstream_gene_variant	0.46	rifampicin
lpqB	3625357	c.-447T>C	upstream_gene_variant	0.46	bedaquiline
lpqB	3625357	c.-447T>C	upstream_gene_variant	0.46	rifampicin
lpqB	3625588	c.-678G>A	upstream_gene_variant	0.62	bedaquiline
lpqB	3625588	c.-678G>A	upstream_gene_variant	0.62	rifampicin
lpqB	3625594	c.-684T>C	upstream_gene_variant	0.67	bedaquiline
lpqB	3625594	c.-684T>C	upstream_gene_variant	0.67	rifampicin
lpqB	3625602	c.-692T>C	upstream_gene_variant	0.67	bedaquiline
lpqB	3625602	c.-692T>C	upstream_gene_variant	0.67	rifampicin
lpqB	3625612	c.-702G>T	upstream_gene_variant	0.71	bedaquiline
lpqB	3625612	c.-702G>T	upstream_gene_variant	0.71	rifampicin
lpqB	3625615	c.-705G>T	upstream_gene_variant	0.67	bedaquiline
lpqB	3625615	c.-705G>T	upstream_gene_variant	0.67	rifampicin
mtrB	3625623	p.Thr331Ala	missense_variant	0.67	bedaquiline
mtrB	3625623	p.Thr331Ala	missense_variant	0.67	rifampicin
lpqB	3625624	c.-714C>G	upstream_gene_variant	0.67	bedaquiline
lpqB	3625624	c.-714C>G	upstream_gene_variant	0.67	rifampicin
lpqB	3625630	c.-720C>G	upstream_gene_variant	0.62	bedaquiline
lpqB	3625630	c.-720C>G	upstream_gene_variant	0.62	rifampicin
mtrB	3625636	p.Ala326Glu	missense_variant	0.62	bedaquiline
mtrB	3625636	p.Ala326Glu	missense_variant	0.62	rifampicin
mtrB	3625645	c.969C>T	synonymous_variant	0.67	bedaquiline
mtrB	3625645	c.969C>T	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
mtrB	3625648	c.964_966delTATinsCC	frameshift_variant&missense_variant	0.67	bedaquiline	Uncertain significance
mtrB	3625648	c.964_966delTATinsCC	frameshift_variant&missense_variant	0.67	rifampicin	Uncertain significance
mtrB	3625656	c.958T>C	synonymous_variant	0.8	bedaquiline	Not assoc w R - Interim
mtrB	3625656	c.958T>C	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
lpqB	3625657	c.-747C>T	upstream_gene_variant	0.8	bedaquiline
lpqB	3625657	c.-747C>T	upstream_gene_variant	0.8	rifampicin
lpqB	3625663	c.-753G>A	upstream_gene_variant	0.89	bedaquiline
lpqB	3625663	c.-753G>A	upstream_gene_variant	0.89	rifampicin
lpqB	3625690	c.-780T>C	upstream_gene_variant	0.93	bedaquiline
lpqB	3625690	c.-780T>C	upstream_gene_variant	0.93	rifampicin
mtrB	3625711	c.903C>T	synonymous_variant	0.91	bedaquiline
mtrB	3625711	c.903C>T	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
mtrB	3625720	c.894G>C	synonymous_variant	0.88	bedaquiline
mtrB	3625720	c.894G>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
mtrB	3625729	c.885A>G	synonymous_variant	0.86	bedaquiline
mtrB	3625729	c.885A>G	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
mtrB	3625732	c.882C>T	synonymous_variant	0.77	bedaquiline
mtrB	3625732	c.882C>T	synonymous_variant	0.77	rifampicin	Not assoc w R - Interim
lpqB	3625735	c.-825C>T	upstream_gene_variant	0.77	bedaquiline
lpqB	3625735	c.-825C>T	upstream_gene_variant	0.77	rifampicin
mtrB	3625753	p.Ala287Gln	missense_variant	0.8	bedaquiline
mtrB	3625753	p.Ala287Gln	missense_variant	0.8	rifampicin
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.78	bedaquiline
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.78	rifampicin
mtrB	3625765	c.849C>G	synonymous_variant	0.78	bedaquiline
mtrB	3625765	c.849C>G	synonymous_variant	0.78	rifampicin	Not assoc w R - Interim
mtrB	3625804	c.808_810delAGGinsCC	frameshift_variant&missense_variant	0.75	bedaquiline	Uncertain significance
mtrB	3625804	c.808_810delAGGinsCC	frameshift_variant&missense_variant	0.75	rifampicin	Uncertain significance
lpqB	3625822	c.-912C>T	upstream_gene_variant	0.76	bedaquiline
lpqB	3625822	c.-912C>T	upstream_gene_variant	0.76	rifampicin
lpqB	3625828	c.-918G>C	upstream_gene_variant	0.71	bedaquiline
lpqB	3625828	c.-918G>C	upstream_gene_variant	0.71	rifampicin
mtrB	3625837	c.777C>G	synonymous_variant	0.74	bedaquiline
mtrB	3625837	c.777C>G	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
lpqB	3625840	c.-930A>G	upstream_gene_variant	0.72	bedaquiline
lpqB	3625840	c.-930A>G	upstream_gene_variant	0.72	rifampicin
mtrB	3625845	p.Ser257Thr	missense_variant	0.67	bedaquiline
mtrB	3625845	p.Ser257Thr	missense_variant	0.67	rifampicin
mtrB	3625852	c.762A>G	synonymous_variant	0.67	bedaquiline
mtrB	3625852	c.762A>G	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
mtrB	3625855	c.759G>A	synonymous_variant	0.64	bedaquiline
mtrB	3625855	c.759G>A	synonymous_variant	0.64	rifampicin	Not assoc w R - Interim
mtrB	3626792	c.-179G>C	upstream_gene_variant	0.54	bedaquiline
mtrB	3626792	c.-179G>C	upstream_gene_variant	0.54	rifampicin
mtrB	3626795	c.-182C>T	upstream_gene_variant	0.58	bedaquiline
mtrB	3626795	c.-182C>T	upstream_gene_variant	0.58	rifampicin
mtrB	3626798	c.-185T>A	upstream_gene_variant	0.64	bedaquiline
mtrB	3626798	c.-185T>A	upstream_gene_variant	0.64	rifampicin
mtrA	3626804	c.546A>G	synonymous_variant	0.67	bedaquiline
mtrA	3626804	c.546A>G	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
mtrB	3626876	c.-263A>G	upstream_gene_variant	0.6	bedaquiline
mtrB	3626876	c.-263A>G	upstream_gene_variant	0.6	rifampicin
mtrB	3626885	c.-272A>C	upstream_gene_variant	0.6	bedaquiline
mtrB	3626885	c.-272A>C	upstream_gene_variant	0.6	rifampicin
mtrB	3626890	c.-277T>C	upstream_gene_variant	0.6	bedaquiline
mtrB	3626890	c.-277T>C	upstream_gene_variant	0.6	rifampicin
mtrB	3626894	c.-281C>T	upstream_gene_variant	0.56	bedaquiline
mtrB	3626894	c.-281C>T	upstream_gene_variant	0.56	rifampicin
mtrB	3626903	c.-290T>C	upstream_gene_variant	0.53	bedaquiline
mtrB	3626903	c.-290T>C	upstream_gene_variant	0.53	rifampicin
mtrA	3626906	c.442_444delAACinsCG	frameshift_variant&missense_variant	0.5	bedaquiline
mtrA	3626906	c.442_444delAACinsCG	frameshift_variant&missense_variant	0.5	rifampicin
mtrA	3626909	c.441C>T	synonymous_variant	0.53	bedaquiline	Not assoc w R - Interim
mtrA	3626909	c.441C>T	synonymous_variant	0.53	rifampicin	Not assoc w R - Interim
mtrA	3626912	c.438T>C	synonymous_variant	0.56	bedaquiline
mtrA	3626912	c.438T>C	synonymous_variant	0.56	rifampicin	Not assoc w R - Interim
mtrB	3626930	c.-317A>G	upstream_gene_variant	0.63	bedaquiline
mtrB	3626930	c.-317A>G	upstream_gene_variant	0.63	rifampicin
mtrB	3626933	c.-320C>T	upstream_gene_variant	0.59	bedaquiline
mtrB	3626933	c.-320C>T	upstream_gene_variant	0.59	rifampicin
mtrA	3626939	c.411A>G	synonymous_variant	0.6	bedaquiline
mtrA	3626939	c.411A>G	synonymous_variant	0.6	rifampicin	Not assoc w R - Interim
mtrB	3626942	c.-329A>C	upstream_gene_variant	0.6	bedaquiline
mtrB	3626942	c.-329A>C	upstream_gene_variant	0.6	rifampicin
mtrA	3626949	p.Ala134Asn	missense_variant	0.57	bedaquiline
mtrA	3626949	p.Ala134Asn	missense_variant	0.57	rifampicin
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.62	bedaquiline
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.62	rifampicin
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.62	bedaquiline
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.62	rifampicin
mtrA	3626962	p.Met130Leu	missense_variant	0.62	bedaquiline
mtrA	3626962	p.Met130Leu	missense_variant	0.62	rifampicin
mtrA	3626969	c.381C>T	synonymous_variant	0.67	bedaquiline	Not assoc w R - Interim
mtrA	3626969	c.381C>T	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.68	bedaquiline
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.68	rifampicin
mtrA	3626978	p.Asp124Glu	missense_variant	0.68	bedaquiline
mtrA	3626978	p.Asp124Glu	missense_variant	0.68	rifampicin	Uncertain significance
mtrB	3626999	c.-386G>C	upstream_gene_variant	0.7	bedaquiline
mtrB	3626999	c.-386G>C	upstream_gene_variant	0.7	rifampicin
mtrB	3627002	c.-389G>C	upstream_gene_variant	0.7	bedaquiline
mtrB	3627002	c.-389G>C	upstream_gene_variant	0.7	rifampicin
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.7	bedaquiline
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.7	rifampicin
mtrB	3627011	c.-398T>G	upstream_gene_variant	0.7	bedaquiline
mtrB	3627011	c.-398T>G	upstream_gene_variant	0.7	rifampicin
mtrB	3627032	c.-419G>C	upstream_gene_variant	0.68	bedaquiline
mtrB	3627032	c.-419G>C	upstream_gene_variant	0.68	rifampicin
mtrA	3627041	c.307_309delATCinsGG	frameshift_variant&missense_variant	0.68	bedaquiline
mtrA	3627041	c.307_309delATCinsGG	frameshift_variant&missense_variant	0.68	rifampicin
mtrB	3627044	c.-431C>T	upstream_gene_variant	0.68	bedaquiline
mtrB	3627044	c.-431C>T	upstream_gene_variant	0.68	rifampicin
mtrB	3627059	c.-446G>C	upstream_gene_variant	0.74	bedaquiline
mtrB	3627059	c.-446G>C	upstream_gene_variant	0.74	rifampicin
mtrB	3627062	c.-449G>A	upstream_gene_variant	0.75	bedaquiline
mtrB	3627062	c.-449G>A	upstream_gene_variant	0.75	rifampicin
mtrA	3627068	c.282T>C	synonymous_variant	0.69	bedaquiline
mtrA	3627068	c.282T>C	synonymous_variant	0.69	rifampicin	Not assoc w R - Interim
mtrB	3627071	c.-458G>C	upstream_gene_variant	0.62	bedaquiline
mtrB	3627071	c.-458G>C	upstream_gene_variant	0.62	rifampicin
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.62	bedaquiline
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.62	rifampicin
mtrA	3627098	c.252A>C	synonymous_variant	0.57	bedaquiline
mtrA	3627098	c.252A>C	synonymous_variant	0.57	rifampicin	Not assoc w R - Interim
mtrB	3627101	c.-488C>G	upstream_gene_variant	0.57	bedaquiline
mtrB	3627101	c.-488C>G	upstream_gene_variant	0.57	rifampicin
mtrB	3627110	c.-497G>C	upstream_gene_variant	0.53	bedaquiline
mtrB	3627110	c.-497G>C	upstream_gene_variant	0.53	rifampicin
alr	3840764	c.657G>C	synonymous_variant	0.86	cycloserine
rpoA	3877638	c.870T>C	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoA	3877647	c.861C>T	synonymous_variant	0.71	rifampicin
rpoA	3877656	c.852T>G	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoA	3877668	c.840A>G	synonymous_variant	0.76	rifampicin
rpoA	3877671	c.837C>G	synonymous_variant	0.76	rifampicin
rpoA	3877677	c.831G>C	synonymous_variant	0.7	rifampicin	Not assoc w R - Interim
rpoA	3877680	c.828G>C	synonymous_variant	0.68	rifampicin	Not assoc w R - Interim
rpoA	3877683	c.825G>C	synonymous_variant	0.65	rifampicin
rpoA	3877686	c.822A>G	synonymous_variant	0.68	rifampicin	Not assoc w R - Interim
rpoA	3877695	c.813C>G	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoA	3877704	c.804G>T	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoA	3877728	c.780C>G	synonymous_variant	0.74	rifampicin
rpoA	3877731	c.777G>T	synonymous_variant	0.74	rifampicin
rpoA	3877734	c.774G>C	synonymous_variant	0.74	rifampicin
rpoA	3877737	c.771G>C	synonymous_variant	0.74	rifampicin
rpoA	3877743	c.765T>C	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoA	3877749	c.759C>T	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoA	3877764	c.744C>G	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoA	3877776	c.732T>C	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoA	3877782	c.726T>C	synonymous_variant	0.78	rifampicin	Not assoc w R - Interim
rpoA	3877785	c.723C>A	synonymous_variant	0.78	rifampicin
rpoA	3877818	c.690A>G	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoA	3877848	c.660C>T	synonymous_variant	0.74	rifampicin	Not assoc w R - Interim
rpoA	3877856	c.652T>C	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoA	3877857	c.651G>A	synonymous_variant	0.72	rifampicin
rpoA	3877866	c.642G>C	synonymous_variant	0.71	rifampicin
rpoA	3877875	c.633T>G	synonymous_variant	0.72	rifampicin
rpoA	3877887	c.621G>C	synonymous_variant	0.76	rifampicin
rpoA	3877893	c.615C>T	synonymous_variant	0.71	rifampicin	Not assoc w R - Interim
rpoA	3877905	c.603A>G	synonymous_variant	0.69	rifampicin	Not assoc w R - Interim
rpoA	3877908	c.600T>C	synonymous_variant	0.67	rifampicin	Not assoc w R - Interim
rpoA	3877920	c.588G>C	synonymous_variant	0.63	rifampicin	Not assoc w R - Interim
rpoA	3877926	c.582G>C	synonymous_variant	0.63	rifampicin
rpoA	3877962	c.546G>T	synonymous_variant	0.66	rifampicin	Not assoc w R - Interim
rpoA	3877971	p.Asp179Glu	missense_variant	0.7	rifampicin	Uncertain significance
rpoA	3877986	c.522G>C	synonymous_variant	0.72	rifampicin
rpoA	3877989	c.519A>G	synonymous_variant	0.72	rifampicin	Not assoc w R - Interim
rpoA	3877995	c.513G>C	synonymous_variant	0.74	rifampicin
rpoA	3878001	c.507A>G	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoA	3878019	c.489A>G	synonymous_variant	0.79	rifampicin
rpoA	3878022	c.486T>C	synonymous_variant	0.79	rifampicin
rpoA	3878025	c.483C>T	synonymous_variant	0.83	rifampicin
rpoA	3878028	c.480G>C	synonymous_variant	0.83	rifampicin
rpoA	3878031	c.477T>C	synonymous_variant	0.83	rifampicin
rpoA	3878034	c.474A>G	synonymous_variant	0.83	rifampicin
rpoA	3878040	c.468T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoA	3878046	c.462T>G	synonymous_variant	0.86	rifampicin
rpoA	3878050	p.Arg153Lys	missense_variant	0.86	rifampicin
rpoA	3878055	c.453A>G	synonymous_variant	0.84	rifampicin
rpoA	3878061	c.447G>A	synonymous_variant	0.91	rifampicin
rpoA	3878067	c.441C>G	synonymous_variant	0.96	rifampicin
rpoA	3878070	c.438T>C	synonymous_variant	0.96	rifampicin
rpoA	3878082	c.426T>C	synonymous_variant	0.96	rifampicin
rpoA	3878103	c.405A>G	synonymous_variant	0.93	rifampicin
rpoA	3878118	c.390T>C	synonymous_variant	0.9	rifampicin
rpoA	3878127	c.381G>C	synonymous_variant	0.87	rifampicin
rpoA	3878143	p.Gly122Asp	missense_variant	0.74	rifampicin	Uncertain significance
rpoA	3878145	c.363C>G	synonymous_variant	0.75	rifampicin
rpoA	3878160	c.348C>G	synonymous_variant	0.76	rifampicin	Not assoc w R - Interim
rpoA	3878163	c.345C>T	synonymous_variant	0.75	rifampicin	Not assoc w R - Interim
rpoA	3878187	c.321C>G	synonymous_variant	0.78	rifampicin
rpoA	3878193	c.315T>C	synonymous_variant	0.78	rifampicin	Not assoc w R - Interim
rpoA	3878197	p.Glu104Ala	missense_variant	0.79	rifampicin	Uncertain significance
rpoA	3878205	c.303T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoA	3878217	c.291A>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoA	3878238	c.270C>T	synonymous_variant	0.79	rifampicin
rpoA	3878244	c.264G>A	synonymous_variant	0.77	rifampicin
rpoA	3878247	c.261G>C	synonymous_variant	0.79	rifampicin
rpoA	3878256	c.252G>C	synonymous_variant	0.77	rifampicin
rpoA	3878264	p.Ser82Gly	missense_variant	0.8	rifampicin
rpoA	3878271	c.237T>C	synonymous_variant	0.81	rifampicin	Not assoc w R - Interim
rpoA	3878283	p.Glu75Asp	missense_variant	0.86	rifampicin	Uncertain significance
rpoA	3878292	c.216T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoA	3878298	c.210A>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoA	3878301	c.207C>G	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
rpoA	3878304	c.204G>A	synonymous_variant	0.8	rifampicin
rpoA	3878310	c.198G>C	synonymous_variant	0.83	rifampicin
rpoA	3878313	c.195G>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoA	3878322	c.186A>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
rpoA	3878331	c.177A>G	synonymous_variant	0.82	rifampicin	Not assoc w R - Interim
rpoA	3878337	c.171T>C	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
clpC1	4038499	p.Ser736Gly	missense_variant	0.62	pyrazinamide
clpC1	4038519	p.Arg729Gln	missense_variant	0.64	pyrazinamide
clpC1	4038530	p.Glu725Asp	missense_variant	0.6	pyrazinamide
clpC1	4038533	p.Arg724Gln	missense_variant	0.6	pyrazinamide
clpC1	4038536	c.2169C>G	synonymous_variant	0.64	pyrazinamide
clpC1	4038551	c.2154C>G	synonymous_variant	0.71	pyrazinamide
clpC1	4038563	c.2142C>T	synonymous_variant	0.76	pyrazinamide
clpC1	4038584	c.2121G>T	synonymous_variant	0.79	pyrazinamide
clpC1	4038587	c.2118C>G	synonymous_variant	0.79	pyrazinamide
clpC1	4038596	c.2109A>G	synonymous_variant	0.78	pyrazinamide
clpC1	4038602	c.2103G>C	synonymous_variant	0.76	pyrazinamide
clpC1	4038623	c.2082A>G	synonymous_variant	0.79	pyrazinamide
clpC1	4038640	p.Asp689Asn	missense_variant	0.76	pyrazinamide
clpC1	4038647	c.2058T>G	synonymous_variant	0.72	pyrazinamide
clpC1	4038658	p.Lys683Gln	missense_variant	0.66	pyrazinamide
clpC1	4038660	c.2044_2045delTCinsAG	synonymous_variant	0.66	pyrazinamide
clpC1	4038662	c.2043T>C	synonymous_variant	0.67	pyrazinamide
clpC1	4038671	c.2034T>G	synonymous_variant	0.75	pyrazinamide	Not assoc w R - Interim
clpC1	4038679	p.Pro676Ala	missense_variant	0.76	pyrazinamide
clpC1	4038683	c.2022T>C	synonymous_variant	0.78	pyrazinamide	Not assoc w R - Interim
clpC1	4038695	c.2010C>G	synonymous_variant	0.78	pyrazinamide
clpC1	4038704	c.2001T>C	synonymous_variant	0.76	pyrazinamide
clpC1	4038710	c.1995G>C	synonymous_variant	0.73	pyrazinamide
clpC1	4038713	c.1992T>C	synonymous_variant	0.73	pyrazinamide
clpC1	4038725	c.1980C>G	synonymous_variant	0.75	pyrazinamide
clpC1	4038740	c.1965G>C	synonymous_variant	0.74	pyrazinamide
clpC1	4038755	c.1950G>C	synonymous_variant	0.76	pyrazinamide
clpC1	4038767	c.1938G>T	synonymous_variant	0.78	pyrazinamide
clpC1	4038770	c.1935C>T	synonymous_variant	0.77	pyrazinamide
clpC1	4038773	c.1932T>C	synonymous_variant	0.78	pyrazinamide
clpC1	4038779	c.1926C>G	synonymous_variant	0.78	pyrazinamide
clpC1	4038782	c.1923G>C	synonymous_variant	0.78	pyrazinamide
clpC1	4038790	c.1915C>T	synonymous_variant	0.8	pyrazinamide	Not assoc w R - Interim
clpC1	4038812	c.1893T>C	synonymous_variant	0.81	pyrazinamide
clpC1	4038815	c.1890G>C	synonymous_variant	0.81	pyrazinamide
clpC1	4038842	c.1863G>C	synonymous_variant	0.76	pyrazinamide
clpC1	4038860	c.1845G>C	synonymous_variant	0.81	pyrazinamide	Not assoc w R - Interim
clpC1	4038878	c.1827A>G	synonymous_variant	0.81	pyrazinamide	Not assoc w R - Interim
clpC1	4038890	c.1815G>A	synonymous_variant	0.8	pyrazinamide
clpC1	4038905	c.1800A>G	synonymous_variant	0.8	pyrazinamide
clpC1	4038908	c.1797C>G	synonymous_variant	0.83	pyrazinamide
clpC1	4038911	c.1794G>T	synonymous_variant	0.83	pyrazinamide
clpC1	4038914	c.1791G>C	synonymous_variant	0.84	pyrazinamide
clpC1	4038917	c.1788C>T	synonymous_variant	0.86	pyrazinamide
clpC1	4038923	c.1782A>G	synonymous_variant	0.86	pyrazinamide
clpC1	4038941	c.1764G>C	synonymous_variant	0.83	pyrazinamide
clpC1	4038953	c.1752A>G	synonymous_variant	0.83	pyrazinamide
clpC1	4038956	c.1749T>C	synonymous_variant	0.84	pyrazinamide
clpC1	4038965	c.1740T>C	synonymous_variant	0.83	pyrazinamide
clpC1	4038971	c.1734T>C	synonymous_variant	0.82	pyrazinamide
clpC1	4038974	c.1731T>C	synonymous_variant	0.85	pyrazinamide	Not assoc w R - Interim
clpC1	4038997	c.1708T>C	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
clpC1	4039004	c.1701C>G	synonymous_variant	0.89	pyrazinamide
clpC1	4039022	c.1683A>G	synonymous_variant	0.9	pyrazinamide
clpC1	4039025	c.1680C>G	synonymous_variant	0.92	pyrazinamide
clpC1	4039046	c.1659C>T	synonymous_variant	0.9	pyrazinamide	Not assoc w R - Interim
clpC1	4039064	c.1641C>T	synonymous_variant	0.86	pyrazinamide
clpC1	4039067	c.1638G>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039079	c.1626C>G	synonymous_variant	0.81	pyrazinamide	Not assoc w R - Interim
clpC1	4039085	c.1620A>G	synonymous_variant	0.82	pyrazinamide
clpC1	4039091	c.1614G>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039097	c.1608G>C	synonymous_variant	0.85	pyrazinamide
clpC1	4039103	c.1602T>A	synonymous_variant	0.83	pyrazinamide
clpC1	4039106	c.1599G>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039112	c.1593C>G	synonymous_variant	0.84	pyrazinamide
clpC1	4039121	c.1584T>C	synonymous_variant	0.81	pyrazinamide
clpC1	4039136	c.1569C>T	synonymous_variant	0.81	pyrazinamide
clpC1	4039145	c.1560G>A	synonymous_variant	0.82	pyrazinamide
clpC1	4039169	c.1536A>G	synonymous_variant	0.79	pyrazinamide
clpC1	4039172	c.1533A>G	synonymous_variant	0.78	pyrazinamide
clpC1	4039178	c.1527G>C	synonymous_variant	0.76	pyrazinamide
clpC1	4039183	c.1522T>C	synonymous_variant	0.78	pyrazinamide
clpC1	4039187	c.1518G>T	synonymous_variant	0.82	pyrazinamide
clpC1	4039190	c.1515C>G	synonymous_variant	0.83	pyrazinamide
clpC1	4039220	c.1485G>C	synonymous_variant	0.91	pyrazinamide
clpC1	4039226	c.1479T>C	synonymous_variant	0.91	pyrazinamide	Not assoc w R - Interim
clpC1	4039241	c.1464G>C	synonymous_variant	0.89	pyrazinamide
clpC1	4039265	c.1440C>T	synonymous_variant	0.88	pyrazinamide
clpC1	4039274	c.1431G>C	synonymous_variant	0.85	pyrazinamide	Not assoc w R - Interim
clpC1	4039286	c.1419T>C	synonymous_variant	0.85	pyrazinamide
clpC1	4039295	c.1410A>C	synonymous_variant	0.84	pyrazinamide
clpC1	4039298	c.1407T>C	synonymous_variant	0.87	pyrazinamide
clpC1	4039310	c.1395A>G	synonymous_variant	0.85	pyrazinamide
clpC1	4039313	c.1392C>G	synonymous_variant	0.85	pyrazinamide
clpC1	4039320	p.Ala462Gly	missense_variant	0.8	pyrazinamide
clpC1	4039322	c.1383T>C	synonymous_variant	0.79	pyrazinamide
clpC1	4039328	c.1377A>C	synonymous_variant	0.82	pyrazinamide
clpC1	4039337	p.Thr456Gln	missense_variant	0.79	pyrazinamide
clpC1	4039352	c.1353C>T	synonymous_variant	0.7	pyrazinamide	Not assoc w R - Interim
clpC1	4039361	c.1344C>G	synonymous_variant	0.67	pyrazinamide
clpC1	4039364	c.1341C>G	synonymous_variant	0.68	pyrazinamide
clpC1	4039382	c.1323C>G	synonymous_variant	0.67	pyrazinamide
clpC1	4039391	c.1314T>G	synonymous_variant	0.67	pyrazinamide
clpC1	4039394	c.1311G>C	synonymous_variant	0.65	pyrazinamide
clpC1	4039397	c.1308A>G	synonymous_variant	0.65	pyrazinamide
clpC1	4039409	c.1296T>C	synonymous_variant	0.7	pyrazinamide
clpC1	4039412	c.1293T>G	synonymous_variant	0.72	pyrazinamide
clpC1	4039415	p.Glu430Asp	missense_variant	0.72	pyrazinamide	Uncertain significance
clpC1	4039430	c.1275T>C	synonymous_variant	0.67	pyrazinamide
clpC1	4039442	c.1263A>G	synonymous_variant	0.68	pyrazinamide
clpC1	4039454	c.1251A>T	synonymous_variant	0.62	pyrazinamide
clpC1	4039463	c.1242C>G	synonymous_variant	0.62	pyrazinamide
clpC1	4039466	c.1239T>C	synonymous_variant	0.65	pyrazinamide
clpC1	4039469	c.1236T>C	synonymous_variant	0.65	pyrazinamide
clpC1	4039472	c.1233G>C	synonymous_variant	0.65	pyrazinamide
clpC1	4039478	c.1227G>C	synonymous_variant	0.65	pyrazinamide
clpC1	4039481	c.1224T>C	synonymous_variant	0.62	pyrazinamide
clpC1	4039484	c.1221T>C	synonymous_variant	0.62	pyrazinamide
clpC1	4039487	c.1218G>A	synonymous_variant	0.64	pyrazinamide
clpC1	4039517	c.1188C>G	synonymous_variant	0.7	pyrazinamide
clpC1	4039541	c.1164C>G	synonymous_variant	0.7	pyrazinamide
clpC1	4039544	c.1161C>T	synonymous_variant	0.7	pyrazinamide
clpC1	4039556	c.1149G>C	synonymous_variant	0.71	pyrazinamide
clpC1	4039559	c.1146C>G	synonymous_variant	0.71	pyrazinamide
clpC1	4039570	p.Met379Leu	missense_variant	0.74	pyrazinamide	Uncertain significance
clpC1	4039574	p.Ala377Gly	missense_variant	0.75	pyrazinamide
clpC1	4039577	c.1128T>C	synonymous_variant	0.76	pyrazinamide	Not assoc w R - Interim
clpC1	4039589	c.1116G>C	synonymous_variant	0.79	pyrazinamide
clpC1	4039592	c.1113G>C	synonymous_variant	0.8	pyrazinamide
clpC1	4039610	c.1095G>C	synonymous_variant	0.86	pyrazinamide
clpC1	4039616	c.1089G>T	synonymous_variant	0.89	pyrazinamide
clpC1	4039622	c.1083C>T	synonymous_variant	0.88	pyrazinamide
clpC1	4039649	c.1056G>C	synonymous_variant	0.96	pyrazinamide
clpC1	4039670	c.1035G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4039682	c.1023C>G	synonymous_variant	0.9	pyrazinamide
clpC1	4039694	c.1011G>C	synonymous_variant	0.88	pyrazinamide
clpC1	4039724	c.981A>G	synonymous_variant	0.89	pyrazinamide
clpC1	4039733	c.972G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039742	c.963C>T	synonymous_variant	0.93	pyrazinamide
clpC1	4039748	c.957G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4039751	c.954A>G	synonymous_variant	0.92	pyrazinamide
clpC1	4039757	c.948A>G	synonymous_variant	0.88	pyrazinamide
clpC1	4039760	c.945T>C	synonymous_variant	0.88	pyrazinamide
clpC1	4039763	c.942C>T	synonymous_variant	0.84	pyrazinamide	Not assoc w R - Interim
clpC1	4039766	c.939T>C	synonymous_variant	0.84	pyrazinamide
clpC1	4039769	c.936C>G	synonymous_variant	0.81	pyrazinamide
clpC1	4039775	c.930G>C	synonymous_variant	0.81	pyrazinamide
clpC1	4039778	c.927A>G	synonymous_variant	0.81	pyrazinamide
clpC1	4039793	c.912C>G	synonymous_variant	0.81	pyrazinamide
clpC1	4039802	c.903G>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039817	c.888A>T	synonymous_variant	0.81	pyrazinamide
clpC1	4039820	c.885T>G	synonymous_variant	0.8	pyrazinamide
clpC1	4039829	c.874_876delTTGinsCC	frameshift_variant&missense_variant	0.78	pyrazinamide
clpC1	4039832	c.873C>G	synonymous_variant	0.77	pyrazinamide
clpC1	4039850	c.855T>C	synonymous_variant	0.8	pyrazinamide
clpC1	4039865	c.840T>C	synonymous_variant	0.77	pyrazinamide
clpC1	4039889	c.816G>C	synonymous_variant	0.85	pyrazinamide
clpC1	4039898	c.807C>G	synonymous_variant	0.86	pyrazinamide
clpC1	4039904	c.801A>G	synonymous_variant	0.87	pyrazinamide
clpC1	4039931	c.774T>C	synonymous_variant	0.91	pyrazinamide
clpC1	4039934	c.771G>A	synonymous_variant	0.91	pyrazinamide
clpC1	4039942	c.763C>T	synonymous_variant	0.94	pyrazinamide
clpC1	4039946	c.759A>G	synonymous_variant	0.93	pyrazinamide
clpC1	4039952	c.753T>C	synonymous_variant	0.9	pyrazinamide
clpC1	4039955	c.750G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4039958	c.747G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4039991	c.714G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4040015	c.690G>C	synonymous_variant	0.91	pyrazinamide
clpC1	4040021	c.684A>T	synonymous_variant	0.87	pyrazinamide
clpC1	4040024	c.681A>G	synonymous_variant	0.86	pyrazinamide
clpC1	4040033	c.672G>C	synonymous_variant	0.85	pyrazinamide
clpC1	4040057	c.648C>T	synonymous_variant	0.85	pyrazinamide
clpC1	4040081	c.624C>G	synonymous_variant	0.93	pyrazinamide
clpC1	4040087	c.618G>C	synonymous_variant	0.93	pyrazinamide
clpC1	4040090	c.613_615delTCTinsAGC	synonymous_variant	0.93	pyrazinamide
clpC1	4040093	c.612C>G	synonymous_variant	0.93	pyrazinamide	Not assoc w R - Interim
clpC1	4040126	c.579C>T	synonymous_variant	0.85	pyrazinamide	Not assoc w R - Interim
clpC1	4040306	c.399G>C	synonymous_variant	0.6	pyrazinamide
clpC1	4040309	c.396C>G	synonymous_variant	0.6	pyrazinamide	Not assoc w R - Interim
clpC1	4040393	c.312G>C	synonymous_variant	0.69	pyrazinamide	Not assoc w R - Interim
clpC1	4040411	c.294T>C	synonymous_variant	0.73	pyrazinamide	Not assoc w R - Interim
clpC1	4040423	c.282A>G	synonymous_variant	0.71	pyrazinamide	Not assoc w R - Interim
clpC1	4040431	c.274T>C	synonymous_variant	0.71	pyrazinamide
clpC1	4040433	c.271_272delAGinsTC	synonymous_variant	0.71	pyrazinamide
clpC1	4040441	c.264C>G	synonymous_variant	0.77	pyrazinamide
clpC1	4040444	c.261C>G	synonymous_variant	0.83	pyrazinamide
clpC1	4040450	c.255A>G	synonymous_variant	0.91	pyrazinamide	Not assoc w R - Interim
clpC1	4040459	c.246C>G	synonymous_variant	0.91	pyrazinamide
clpC1	4040462	c.243C>G	synonymous_variant	0.91	pyrazinamide
clpC1	4040465	c.240T>C	synonymous_variant	0.91	pyrazinamide
clpC1	4040468	c.237G>C	synonymous_variant	0.91	pyrazinamide
clpC1	4040471	c.234T>C	synonymous_variant	0.91	pyrazinamide	Not assoc w R - Interim
clpC1	4040477	c.228G>T	synonymous_variant	0.91	pyrazinamide
clpC1	4040480	c.225T>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4040486	c.219G>A	synonymous_variant	0.93	pyrazinamide
clpC1	4040495	c.210C>G	synonymous_variant	0.88	pyrazinamide
clpC1	4040522	c.183T>C	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
clpC1	4040531	c.174T>C	synonymous_variant	0.91	pyrazinamide
clpC1	4040546	c.159G>C	synonymous_variant	0.91	pyrazinamide
clpC1	4040561	c.144A>G	synonymous_variant	0.85	pyrazinamide
clpC1	4040573	c.132T>A	synonymous_variant	0.85	pyrazinamide
clpC1	4040579	c.126A>G	synonymous_variant	0.85	pyrazinamide
clpC1	4040582	c.123G>C	synonymous_variant	0.85	pyrazinamide	Not assoc w R - Interim
clpC1	4040585	c.120A>G	synonymous_variant	0.85	pyrazinamide
clpC1	4040588	c.117T>C	synonymous_variant	0.81	pyrazinamide
clpC1	4040591	c.114C>T	synonymous_variant	0.81	pyrazinamide
clpC1	4040594	c.111G>T	synonymous_variant	0.81	pyrazinamide
clpC1	4040597	c.108C>T	synonymous_variant	0.81	pyrazinamide
clpC1	4040600	c.105A>G	synonymous_variant	0.81	pyrazinamide
clpC1	4040603	c.102T>G	synonymous_variant	0.81	pyrazinamide
clpC1	4040606	c.99T>C	synonymous_variant	0.81	pyrazinamide
clpC1	4040618	c.87C>G	synonymous_variant	0.83	pyrazinamide
clpC1	4040644	c.61A>C	synonymous_variant	0.83	pyrazinamide
clpC1	4040648	c.57G>A	synonymous_variant	0.83	pyrazinamide
clpC1	4040654	c.51G>A	synonymous_variant	0.84	pyrazinamide
clpC1	4040657	c.48T>G	synonymous_variant	0.84	pyrazinamide	Not assoc w R - Interim
panD	4044138	c.144T>C	synonymous_variant	0.43	pyrazinamide	Not assoc w R - Interim
panD	4044147	c.135C>G	synonymous_variant	0.5	pyrazinamide
panD	4044150	c.132A>G	synonymous_variant	0.5	pyrazinamide
panD	4044156	c.126A>G	synonymous_variant	0.5	pyrazinamide	Not assoc w R - Interim
panD	4044159	c.123C>T	synonymous_variant	0.5	pyrazinamide
panD	4044165	c.117G>C	synonymous_variant	0.54	pyrazinamide
panD	4044177	c.105C>G	synonymous_variant	0.5	pyrazinamide	Not assoc w R - Interim
panD	4044180	p.Asp34Glu	missense_variant	0.54	pyrazinamide
panD	4044188	c.94T>C	synonymous_variant	0.58	pyrazinamide
panD	4044189	c.93C>T	synonymous_variant	0.58	pyrazinamide
panD	4044195	c.87T>C	synonymous_variant	0.58	pyrazinamide
panD	4044210	c.72C>T	synonymous_variant	0.54	pyrazinamide
panD	4044213	c.69C>G	synonymous_variant	0.54	pyrazinamide
panD	4044216	c.66C>T	synonymous_variant	0.54	pyrazinamide
embC	4240717	c.855T>C	synonymous_variant	0.58	ethambutol
embC	4240768	c.906G>A	synonymous_variant	0.6	ethambutol	Not assoc w R - Interim
embC	4240780	c.918T>C	synonymous_variant	0.63	ethambutol
embC	4240783	c.921G>C	synonymous_variant	0.63	ethambutol
embC	4240786	c.924C>T	synonymous_variant	0.67	ethambutol
embC	4240789	c.927T>C	synonymous_variant	0.71	ethambutol
embC	4240819	c.957A>C	synonymous_variant	0.72	ethambutol
embC	4240828	c.966G>A	synonymous_variant	0.67	ethambutol
embC	4240831	c.969T>G	synonymous_variant	0.71	ethambutol
embC	4241074	c.1212G>C	synonymous_variant	0.5	ethambutol
embC	4241095	c.1233C>T	synonymous_variant	0.56	ethambutol
embC	4241104	c.1242G>A	synonymous_variant	0.56	ethambutol	Not assoc w R - Interim
embC	4241107	c.1245G>C	synonymous_variant	0.56	ethambutol
embC	4241109	p.Ala416Gly	missense_variant	0.56	ethambutol
embC	4241121	p.Ser420Asn	missense_variant	0.6	ethambutol
embB	4247407	c.894G>C	synonymous_variant	0.47	ethambutol
embB	4247426	p.Gly305Gln	missense_variant	0.55	ethambutol
embB	4247434	c.921C>G	synonymous_variant	0.58	ethambutol
embB	4247437	c.924A>C	synonymous_variant	0.58	ethambutol
embB	4247440	c.927C>G	synonymous_variant	0.58	ethambutol
embB	4247449	c.936C>T	synonymous_variant	0.58	ethambutol
embB	4247464	c.951C>G	synonymous_variant	0.59	ethambutol
embB	4247470	c.957T>C	synonymous_variant	0.68	ethambutol
embB	4247491	c.978G>C	synonymous_variant	0.73	ethambutol
embB	4247497	c.984T>C	synonymous_variant	0.74	ethambutol
embB	4247511	p.Tyr333Phe	missense_variant	0.78	ethambutol
embB	4247527	c.1014G>C	synonymous_variant	0.78	ethambutol
embB	4247536	c.1023C>G	synonymous_variant	0.74	ethambutol
embB	4247554	c.1041T>C	synonymous_variant	0.64	ethambutol
embB	4247555	c.1042_1044delCTGinsAC	frameshift_variant&missense_variant	0.64	ethambutol
embB	4247566	c.1053C>A	synonymous_variant	0.74	ethambutol
embB	4247572	c.1059A>C	synonymous_variant	0.74	ethambutol
embB	4247578	c.1065_1066insATCTGT	conservative_inframe_insertion	0.65	ethambutol
embB	4247581	c.1069_1074delGCCGGG	conservative_inframe_deletion	0.74	ethambutol
embB	4247590	c.1077A>G	synonymous_variant	0.74	ethambutol	Not assoc w R - Interim
embB	4247629	c.1116C>G	synonymous_variant	0.67	ethambutol
embB	4248070	c.1557T>C	synonymous_variant	0.62	ethambutol
embB	4248085	c.1572T>C	synonymous_variant	0.59	ethambutol
embB	4248097	c.1584C>G	synonymous_variant	0.56	ethambutol
embB	4248199	c.1686A>G	synonymous_variant	0.56	ethambutol
embB	4248200	p.Ile563Val	missense_variant	0.56	ethambutol
embB	4248206	c.1693_1695delAGCinsGT	frameshift_variant&missense_variant	0.56	ethambutol
embB	4248220	c.1707A>G	synonymous_variant	0.56	ethambutol	Not assoc w R - Interim
embB	4248225	p.Ala571Val	missense_variant	0.53	ethambutol	Uncertain significance
embB	4248233	c.1720C>T	synonymous_variant	0.6	ethambutol
embB	4248242	p.Val577Ile	missense_variant	0.54	ethambutol
embB	4248252	p.Gly580Ala	missense_variant	0.54	ethambutol
embB	4248264	p.Phe584Cys	missense_variant	0.54	ethambutol
embB	4248277	c.1764G>C	synonymous_variant	0.54	ethambutol

TB-Profiler result