TB-Profiler result

Run: ERR3797017
Summary

Run ID: ERR3797017

Sample name:

Date: 2024-04-16T12:23:48.284884

Number of reads: 989068

Percentage reads mapped: 35.83

Median coverage: 44.0

Strain: La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.2.2.1 Euro-American None 0.06
lineage4.3.2.1 Euro-American (LAM) RD761 0.07
lineage4.6.4 Euro-American None 0.15
lineage3.1.2.2 East-African-Indian RD750 0.14
lineage4 Euro-American None 0.68
lineage2.1 East-Asian (non-Beijing) None 0.09
lineage4.8.1 Euro-American (mainly T) RD219 0.08
lineage4.9 Euro-American (H37Rv-like) None 0.8
La1.7.1 M.bovis None 0.13
La3 M.orygis None 0.2
La1.6 M.bovis None 0.14
M.canetti M.canetti None 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.592_594delGCCinsCG Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.289_291delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.391_393delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD c.196_198delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.598_600delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.607_609delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.772_774delACGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.391_393delACCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1051_1053delATGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.592_594delGCCinsCG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303219 c.289_291delTTAinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303321 c.391_393delGTTinsAC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsAG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
pepQ 2859825 c.592_594delGCCinsCG frameshift_variant&synonymous_variant 0.95 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
fbiD 3339313 c.196_198delGAAinsAG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641140 c.598_600delATCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641149 c.607_609delCTGinsAC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641314 c.772_774delACGinsGC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641925 c.391_393delACCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642585 c.1051_1053delATGinsTC frameshift_variant&missense_variant 0.85 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 0.98 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.88 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.89 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.82 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 558 c.558G>T synonymous_variant 1.0 isoniazid
dnaA 561 c.561C>T synonymous_variant 1.0 isoniazid
dnaA 567 c.567C>T synonymous_variant 1.0 isoniazid
dnaA 570 c.570C>G synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>T synonymous_variant 1.0 isoniazid
dnaA 624 c.624C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 633 c.633T>A synonymous_variant 1.0 isoniazid
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 639 c.639C>T synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 771 c.771A>C synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 804 c.804G>A synonymous_variant 1.0 isoniazid
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 834 c.834C>T synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>A synonymous_variant 1.0 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 1.0 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 1.0 isoniazid
dnaA 1051 c.1051_1053delCTCinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 1.0 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>T synonymous_variant 1.0 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 1.0 isoniazid
dnaA 1149 c.1149C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1210 p.Ala404Ser missense_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.96 isoniazid
dnaA 1314 c.1314A>C synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1335 c.1335G>A synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 1.0 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1359 c.1359G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1368 c.1368T>C synonymous_variant 1.0 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 1.0 isoniazid
dnaA 1377 c.1377G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1395 c.1395G>A synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 1.0 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1461 c.1461C>A synonymous_variant 1.0 isoniazid
gyrB 6022 c.783G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6025 c.786A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6034 c.795C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6037 c.798C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6047 p.Ala270Pro missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6057 p.Ser273Asn missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6070 c.831C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6084 c.846delC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6091 c.853dupC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6229 c.990G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6262 c.1023G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6313 c.-989C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6316 c.-986G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6337 c.1098G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6355 c.-947G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6685 c.1446C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6772 c.1533C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6805 c.1566G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6850 c.-452C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6901 c.-401G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6902 c.1663_1665delCTCinsTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6913 c.1674C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6943 c.-359G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861_1863delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7565 c.264C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7577 c.276C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7880 c.579C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8321 c.1020C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8468 c.1167C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8573 c.1272G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8595 p.Ala432Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8618 c.1317G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8637 c.1336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8684 c.1383G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8738 c.1437G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8954 c.1653G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8965 c.1664_1665insG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8968 c.1668delG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9131 c.1830G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9134 c.1833C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9188 c.1887C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9218 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9276 c.1975C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 c.1999_2001delGCCinsTG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9344 c.2043C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
Rv0010c 13852 c.-294A>G upstream_gene_variant 0.85 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 0.87 isoniazid
Rv0010c 13864 c.-306A>G upstream_gene_variant 0.88 isoniazid
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.88 isoniazid
Rv0010c 13879 c.-321T>C upstream_gene_variant 0.88 isoniazid
Rv0010c 13885 c.-327C>T upstream_gene_variant 0.88 isoniazid
Rv0010c 13891 c.-334_-333delCGinsGT upstream_gene_variant 0.88 isoniazid
Rv0010c 13894 c.-336C>G upstream_gene_variant 0.88 isoniazid
Rv0010c 13903 c.-347_-345delGTAinsAT upstream_gene_variant 0.88 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.88 isoniazid
fgd1 490734 c.-49A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490744 c.-39T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490756 c.-27_-23delTTTATinsAC upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490764 c.-19delAinsGAATC upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490777 c.-6G>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490781 c.-2T>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490806 c.24C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490926 c.144C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491031 c.249C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491038 p.Ile86Val missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491137 p.Glu119Gln missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491169 c.387C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491219 p.Asp146Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491229 c.447C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491391 c.609C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491393 p.Thr204Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491397 p.Glu205Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491415 c.633A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491418 c.636A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491421 c.639A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491430 c.648T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491436 c.654T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491442 c.660A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491443 p.Ser221Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491453 p.Gly224Asp missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491517 c.735C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491559 c.777G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491583 c.801G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491686 p.Thr302Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491700 c.918C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574640 c.-708G>A upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574664 c.-684G>C upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 0.91 ethionamide
isoniazid
mshA 574679 c.-669C>T upstream_gene_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574683 c.-665T>C upstream_gene_variant 0.93 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.96 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574742 c.-606G>A upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 574763 c.-585T>C upstream_gene_variant 0.94 ethionamide
isoniazid Uncertain significance
mshA 574782 c.-566C>G upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574792 c.-556_-555delTCinsCG upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 574794 c.-554C>T upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574799 c.-549T>C upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574802 c.-546A>G upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574803 c.-545A>C upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574814 c.-534T>C upstream_gene_variant 0.83 ethionamide
isoniazid
mshA 574835 c.-513T>C upstream_gene_variant 0.83 ethionamide
isoniazid Uncertain significance
mshA 574970 c.-378A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574979 c.-369G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575000 c.-348C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575003 c.-345G>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575011 c.-337G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575021 c.-327G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575022 c.-326C>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575030 c.-318T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575034 c.-314_-312delTTAinsAG upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575042 c.-306T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575051 c.-297A>G upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575060 c.-288G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575063 c.-285T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575072 c.-276G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575084 c.-264T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575087 c.-261C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575102 c.-246G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575530 c.183C>A synonymous_variant 0.94 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575542 c.195C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575560 c.213C>T synonymous_variant 0.97 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.97 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.97 ethionamide
isoniazid
mshA 575587 c.240C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575649 p.Val101Glu missense_variant 0.97 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.98 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575786 p.Tyr147His missense_variant 0.98 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575824 c.477T>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575875 c.528C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575977 c.630G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575992 c.645C>T synonymous_variant 0.96 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 576007 c.660A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 576012 p.Arg222Lys missense_variant 0.93 ethionamide
isoniazid
mshA 576017 p.Val224Leu missense_variant 0.93 ethionamide
isoniazid
mshA 576026 c.679_681delCTTinsAC frameshift_variant&missense_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576032 p.Gly229His missense_variant 0.92 ethionamide
isoniazid
mshA 576046 c.699A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576049 c.702A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576070 c.723T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 576077 c.730C>T synonymous_variant 0.95 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R
mshA 576097 c.750T>C synonymous_variant 0.93 ethionamide
isoniazid
ccsA 620133 c.243G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620139 c.249C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620145 c.255T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620167 p.Ala93Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620170 p.Cys94Ser missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620187 c.297C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Leu missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620275 c.385C>T synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>A synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620409 c.519C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.95 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620448 c.558C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620454 c.564C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620461 c.571_573delGTCinsAT frameshift_variant&missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620483 p.Val198Ala missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAG frameshift_variant&missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>G synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.96 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620829 c.939G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
Rv0565c 656052 c.1419A>C synonymous_variant 1.0 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656076 c.1395C>T synonymous_variant 1.0 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 1.0 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 1.0 ethionamide
Rv0565c 656091 c.1380T>C synonymous_variant 1.0 ethionamide
Rv0565c 656100 c.1371G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656115 c.1356G>A synonymous_variant 1.0 ethionamide
Rv0565c 656127 c.1342_1344delTACinsCT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656131 p.Pro447Leu missense_variant 1.0 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 1.0 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 1.0 ethionamide
Rv0565c 656145 c.1326T>C synonymous_variant 1.0 ethionamide
Rv0565c 656172 c.1299A>G synonymous_variant 1.0 ethionamide
Rv0565c 656175 c.1296G>A synonymous_variant 1.0 ethionamide
Rv0565c 656179 p.Asp431Pro missense_variant 1.0 ethionamide
Rv0565c 656238 c.1233A>G synonymous_variant 1.0 ethionamide
Rv0565c 656244 c.1227A>G synonymous_variant 1.0 ethionamide
Rv0565c 656247 c.1224A>G synonymous_variant 1.0 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 1.0 ethionamide
Rv0565c 656282 c.1189C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656304 c.1167T>C synonymous_variant 1.0 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656367 c.1104G>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656370 c.1101T>C synonymous_variant 1.0 ethionamide
Rv0565c 656380 p.Glu364Gly missense_variant 1.0 ethionamide
Rv0565c 656391 c.1078_1080delCTCinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656396 p.Ser359Gly missense_variant 1.0 ethionamide
Rv0565c 656403 c.1068C>G synonymous_variant 1.0 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 1.0 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 1.0 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 1.0 ethionamide
Rv0565c 656447 p.Ile342Val missense_variant 1.0 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 1.0 ethionamide
Rv0565c 656476 p.Lys332Ala missense_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656502 c.969C>T synonymous_variant 1.0 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656539 p.Ser311Asp missense_variant 1.0 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 1.0 ethionamide
Rv0565c 656546 p.Ile309Val missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656568 c.903G>C synonymous_variant 1.0 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 1.0 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 1.0 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 1.0 ethionamide
Rv0565c 656804 p.Ser223Gly missense_variant 1.0 ethionamide
Rv0565c 656814 c.657A>G synonymous_variant 1.0 ethionamide
Rv0565c 656822 p.Ile217Val missense_variant 1.0 ethionamide
Rv0565c 656823 c.648G>C synonymous_variant 1.0 ethionamide
Rv0565c 656826 c.645C>T synonymous_variant 1.0 ethionamide
Rv0565c 656835 c.636C>G synonymous_variant 1.0 ethionamide
Rv0565c 656838 c.633A>C synonymous_variant 1.0 ethionamide
Rv0565c 656853 c.618A>G synonymous_variant 1.0 ethionamide
Rv0565c 656856 c.615G>A synonymous_variant 1.0 ethionamide
Rv0565c 656860 p.Glu204Ala missense_variant 1.0 ethionamide
Rv0565c 656865 c.606G>C synonymous_variant 1.0 ethionamide
Rv0565c 656869 p.Asp201Arg missense_variant 1.0 ethionamide
Rv0565c 656871 c.598_600delACCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656880 c.591C>G synonymous_variant 1.0 ethionamide
Rv0565c 656889 c.582A>G synonymous_variant 1.0 ethionamide
Rv0565c 656901 c.570C>G synonymous_variant 1.0 ethionamide
Rv0565c 656924 p.Ile183Val missense_variant 1.0 ethionamide
Rv0565c 656926 p.Lys182Arg missense_variant 1.0 ethionamide
Rv0565c 656946 p.Asp175Gly missense_variant 1.0 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 1.0 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 1.0 ethionamide
Rv0565c 656973 c.498A>C synonymous_variant 1.0 ethionamide
Rv0565c 656976 c.493_495delGCGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656991 c.480G>A synonymous_variant 1.0 ethionamide
Rv0565c 656997 c.474C>G synonymous_variant 1.0 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657043 p.Ser143Thr missense_variant 1.0 ethionamide
Rv0565c 657046 p.Gly142Ala missense_variant 1.0 ethionamide
Rv0565c 657220 p.Ala84Val missense_variant 1.0 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 1.0 ethionamide
Rv0565c 657234 c.237C>A synonymous_variant 1.0 ethionamide
Rv0565c 657241 p.Glu77Arg missense_variant 1.0 ethionamide
Rv0565c 657243 c.228C>G synonymous_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657317 c.154C>T synonymous_variant 1.0 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 1.0 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 1.0 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 1.0 ethionamide
Rv0565c 657369 c.100_102delCAGinsGC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657381 c.90A>G synonymous_variant 1.0 ethionamide
Rv0565c 657385 p.Ile29Ser missense_variant 1.0 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 1.0 ethionamide
Rv0565c 657405 c.64_66delCTGinsAT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657408 c.63A>C synonymous_variant 1.0 ethionamide
Rv0565c 657417 c.54C>T synonymous_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731747 c.-183T>C upstream_gene_variant 0.95 isoniazid
hadA 731748 c.-182_-180delTTGinsCC upstream_gene_variant 0.95 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.94 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.94 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.94 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 0.93 isoniazid
hadA 731817 c.-113C>T upstream_gene_variant 0.93 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732060 p.Gly44Ala missense_variant 1.0 isoniazid
hadA 732064 c.135C>G synonymous_variant 1.0 isoniazid
hadA 732070 c.141A>G synonymous_variant 1.0 isoniazid
hadA 732076 c.147G>C synonymous_variant 1.0 isoniazid
hadA 732079 c.150T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732085 c.156C>G synonymous_variant 1.0 isoniazid
hadA 732094 c.165T>C synonymous_variant 1.0 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732130 c.201C>G synonymous_variant 1.0 isoniazid
hadA 732133 c.204G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732134 p.Ala69Ser missense_variant 1.0 isoniazid
hadA 732151 c.222T>C synonymous_variant 1.0 isoniazid
hadA 732154 c.225G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732164 p.Thr79Val missense_variant 1.0 isoniazid
hadA 732167 p.Ala80Thr missense_variant 1.0 isoniazid
hadA 732172 p.Glu81Asp missense_variant 1.0 isoniazid
hadA 732173 p.Ala82Gln missense_variant 1.0 isoniazid
hadA 732190 c.261A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732209 p.Glu94Gln missense_variant 1.0 isoniazid
hadA 732214 c.285A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732234 p.Lys102Arg missense_variant 1.0 isoniazid Uncertain significance
hadA 732238 c.309G>C synonymous_variant 1.0 isoniazid
hadA 732250 c.321C>G synonymous_variant 1.0 isoniazid
hadA 732253 c.324T>C synonymous_variant 1.0 isoniazid
hadA 732259 c.330T>C synonymous_variant 1.0 isoniazid
hadA 732279 p.Gly117Ala missense_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732319 c.390G>A synonymous_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732328 p.Asp133Glu missense_variant 1.0 isoniazid Uncertain significance
hadA 732329 c.400_402delCTCinsAT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732334 c.405G>C synonymous_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732369 p.Gly147Ala missense_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732389 p.Ser154Thr missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734076 c.-178_-176delGCCinsAG upstream_gene_variant 0.82 rifampicin
nusG 734093 c.-161A>G upstream_gene_variant 0.89 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.9 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.96 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.96 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.97 rifampicin
nusG 734156 c.-98C>T upstream_gene_variant 0.97 rifampicin Uncertain significance
nusG 734173 c.-81C>G upstream_gene_variant 0.97 rifampicin
nusG 734175 c.-79_-77delGGTinsCTC upstream_gene_variant 0.97 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734193 c.-61A>G upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734224 c.-30_-26delGCTCGinsCATTGC upstream_gene_variant 1.0 rifampicin
nusG 734233 c.-21T>C upstream_gene_variant 1.0 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 1.0 rifampicin
nusG 734274 p.Asp7Glu missense_variant 0.92 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.82 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.89 rifampicin
nusG 734409 c.156T>C synonymous_variant 0.97 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.97 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.97 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.98 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.98 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734470 c.217_219delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734566 c.313C>T synonymous_variant 0.95 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.93 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734610 c.357C>G synonymous_variant 0.93 rifampicin
nusG 734619 c.366G>A synonymous_variant 0.93 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.94 rifampicin
nusG 734640 c.387C>T synonymous_variant 0.89 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.88 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.85 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734658 c.405A>G synonymous_variant 0.84 rifampicin Not assoc w R
nusG 734661 c.408A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
nusG 734664 c.411T>G synonymous_variant 0.84 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.84 rifampicin
nusG 734676 c.423G>C synonymous_variant 0.84 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsAG frameshift_variant&missense_variant 0.89 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.95 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.95 rifampicin
nusG 734715 c.462G>T synonymous_variant 0.94 rifampicin
nusG 734717 p.Gly155Ala missense_variant 0.94 rifampicin
nusG 734719 c.466_468delTCGinsGC frameshift_variant&missense_variant 0.94 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.95 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.96 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.96 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.95 rifampicin
nusG 734764 p.Ala171Thr missense_variant 0.96 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734792 p.Val180Ala missense_variant 1.0 rifampicin
nusG 734800 p.Val183Ile missense_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.98 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.98 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.98 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.97 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.96 rifampicin
nusG 734931 c.678A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734940 c.687G>A synonymous_variant 0.94 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 0.93 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoB 759656 c.-151A>C upstream_gene_variant 0.89 rifampicin
rpoB 759657 c.-150G>T upstream_gene_variant 0.89 rifampicin
rpoB 759659 c.-148T>C upstream_gene_variant 0.89 rifampicin
rpoB 759665 c.-141delT upstream_gene_variant 0.89 rifampicin
rpoB 759671 c.-136G>T upstream_gene_variant 0.89 rifampicin
rpoB 759672 c.-135G>A upstream_gene_variant 0.89 rifampicin
rpoB 759681 c.-125_-124delGT upstream_gene_variant 0.9 rifampicin
rpoB 759715 c.-92_-91delGAinsT upstream_gene_variant 0.88 rifampicin
rpoB 759726 c.-81A>G upstream_gene_variant 0.88 rifampicin
rpoB 759732 c.-75C>T upstream_gene_variant 0.87 rifampicin
rpoB 759741 c.-66_-65insA upstream_gene_variant 0.82 rifampicin
rpoB 759748 c.-59_-58insC upstream_gene_variant 0.8 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.91 rifampicin
rpoB 760073 c.267G>C synonymous_variant 0.92 rifampicin
rpoB 760091 c.285G>T synonymous_variant 0.96 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>T synonymous_variant 0.97 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.97 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.93 rifampicin Not assoc w R
rpoB 760118 c.312T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.97 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.98 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.98 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.98 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.98 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.97 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 0.97 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760528 p.Gln241Arg missense_variant 0.98 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.98 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760716 c.910_912delCGCinsAG frameshift_variant&missense_variant 0.91 rifampicin
rpoB 760799 c.993C>T synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.94 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.95 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsGA frameshift_variant&missense_variant 0.92 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 0.94 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.97 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.97 rifampicin
rpoB 760934 c.1128C>G synonymous_variant 0.97 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.94 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.98 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761196 c.1390C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.98 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.97 rifampicin
rpoB 761309 c.1503C>T synonymous_variant 0.96 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761336 c.1530C>T synonymous_variant 0.97 rifampicin
rpoB 761339 c.1533C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 0.91 rifampicin
rpoB 761348 c.1542C>G synonymous_variant 0.94 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.94 rifampicin
rpoB 761357 c.1551G>C synonymous_variant 0.94 rifampicin
rpoB 761362 p.Ser519Thr missense_variant 0.94 rifampicin
rpoB 761375 c.1569G>C synonymous_variant 0.94 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.89 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761505 c.1699_1701delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>G synonymous_variant 1.0 rifampicin
rpoB 761552 c.1746G>C synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.98 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.98 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.98 rifampicin
rpoB 761720 c.1915_1916delGA frameshift_variant 0.98 rifampicin
rpoB 761724 p.Glu640Thr missense_variant 0.98 rifampicin
rpoB 761728 c.1923_1924insCC frameshift_variant 0.98 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.98 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.98 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761840 c.2034C>A synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762023 c.2217C>T synonymous_variant 1.0 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 c.2491C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.98 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.97 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.97 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762490 p.Val895Ala missense_variant 0.96 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.94 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 0.96 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.96 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.95 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.95 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.94 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 1.0 rifampicin
rpoC 762734 c.-636G>A upstream_gene_variant 1.0 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 1.0 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 762770 c.-600C>G upstream_gene_variant 1.0 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.98 rifampicin
rpoC 763082 c.-288C>G upstream_gene_variant 0.98 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763184 c.3378C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.98 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763268 c.-102C>A upstream_gene_variant 1.0 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763537 c.168C>G synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>G synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>A synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>A synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763790 c.421_423delGAGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763816 c.447C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763871 p.Gly168Thr missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763927 c.558C>G synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763963 c.594C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.99 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.99 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.99 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.99 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764245 c.876C>G synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>G synonymous_variant 0.98 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764339 c.970C>T synonymous_variant 0.98 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.95 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764429 c.1060C>T synonymous_variant 1.0 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764438 c.1069_1071delCTGinsTA frameshift_variant&stop_gained 1.0 rifampicin
rpoC 764443 c.1074C>T synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>A synonymous_variant 1.0 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>T synonymous_variant 1.0 rifampicin
rpoC 764467 c.1098C>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>G synonymous_variant 1.0 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 1.0 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 1.0 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 1.0 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.98 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.98 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.98 rifampicin
rpoC 764851 c.1482C>T synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489_1491delTTGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764861 c.1492C>T synonymous_variant 1.0 rifampicin
rpoC 764867 c.1498_1500delCGCinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764875 c.1506C>G synonymous_variant 1.0 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764881 c.1512G>C synonymous_variant 1.0 rifampicin
rpoC 764885 c.1516_1518delCGGinsAA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764986 c.1617C>T synonymous_variant 1.0 rifampicin
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765006 c.1638_1642delTTTGA frameshift_variant 1.0 rifampicin
rpoC 765013 c.1644_1645insTCTCG frameshift_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>T synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 1.0 rifampicin
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765202 c.1833C>G synonymous_variant 1.0 rifampicin
rpoC 765208 c.1839T>C synonymous_variant 1.0 rifampicin
rpoC 765220 c.1851A>G synonymous_variant 1.0 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 1.0 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 1.0 rifampicin
rpoC 765247 c.1878C>T synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765307 c.1938C>T synonymous_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Thr missense_variant 1.0 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.99 rifampicin
rpoC 765612 p.His748Arg missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765673 p.Asp768Glu missense_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765823 c.2454C>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>G synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>G synonymous_variant 1.0 rifampicin
rpoC 766009 c.2640G>T synonymous_variant 1.0 rifampicin
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 1.0 rifampicin
rpoC 766054 c.2685C>T synonymous_variant 1.0 rifampicin
rpoC 766063 c.2694C>T synonymous_variant 0.98 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 1.0 rifampicin
rpoC 766084 c.2715A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766085 p.Pro906Ala missense_variant 1.0 rifampicin Not assoc w R
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766168 c.2799C>G synonymous_variant 1.0 rifampicin
rpoC 766178 p.Ile937Val missense_variant 1.0 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 1.0 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 1.0 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 1.0 rifampicin
rpoC 766211 p.Glu948Ser missense_variant 1.0 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766222 c.2853T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766231 c.2862T>G synonymous_variant 1.0 rifampicin
rpoC 766234 c.2865T>G synonymous_variant 1.0 rifampicin
rpoC 766237 c.2868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766240 c.2871T>C synonymous_variant 1.0 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 1.0 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 1.0 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.97 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766285 c.2916C>G synonymous_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.98 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.98 rifampicin
rpoC 766486 c.3117A>C synonymous_variant 0.98 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.98 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.98 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.98 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.98 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.98 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.98 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.98 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.98 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.98 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 0.98 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.98 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.98 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766627 c.3258G>C synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.99 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.99 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.97 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>A synonymous_variant 0.98 rifampicin
rpoC 766864 c.3495G>C synonymous_variant 0.98 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 0.98 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.97 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.97 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766923 p.Glu1185Gly missense_variant 1.0 rifampicin
rpoC 766931 c.3562_3564delGCAinsTG frameshift_variant&stop_gained 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767032 c.3663G>C synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>G synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>G synonymous_variant 0.98 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.97 rifampicin
rpoC 767188 c.3819G>A synonymous_variant 0.98 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767242 p.Gln1291His missense_variant 0.95 rifampicin
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>G synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775829 c.2652C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775832 c.2647_2649delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775838 c.2643G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775847 c.2634G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775851 p.Ser877Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775985 c.2496C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777125 c.1356C>T synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 777142 p.Val447Leu missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777163 p.Gln440Lys missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777191 c.1290C>A synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777194 p.Glu429Ala missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777200 c.1281C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 777209 c.1272C>T synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 777251 c.1230C>A synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777254 c.1227G>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777269 c.1212T>C synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781130 c.-430_-429delACinsGT upstream_gene_variant 1.0 streptomycin
rpsL 781137 c.-423G>C upstream_gene_variant 1.0 streptomycin
rpsL 781138 c.-422C>G upstream_gene_variant 1.0 streptomycin
rpsL 781143 c.-417T>G upstream_gene_variant 1.0 streptomycin
rpsL 781158 c.-402C>G upstream_gene_variant 1.0 streptomycin
rpsL 781161 c.-399G>A upstream_gene_variant 1.0 streptomycin
rpsL 781164 c.-396T>C upstream_gene_variant 1.0 streptomycin
rpsL 781170 c.-390G>C upstream_gene_variant 1.0 streptomycin
rpsL 781179 c.-381T>C upstream_gene_variant 1.0 streptomycin
rpsL 781182 c.-378G>T upstream_gene_variant 1.0 streptomycin
rpsL 781189 c.-371T>C upstream_gene_variant 1.0 streptomycin
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.98 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.98 streptomycin
rpsL 781682 c.123T>G synonymous_variant 0.99 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.99 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.99 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.99 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.99 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781820 c.261G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 1.0 linezolid
rplC 800555 c.-254C>T upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800576 c.-233C>T upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.98 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>G upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>A upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10_-8delGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800874 c.66A>G synonymous_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>C synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800967 c.159C>A synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800973 c.165C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 801004 p.Leu66Val missense_variant 1.0 linezolid
rplC 801009 c.201A>C synonymous_variant 1.0 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801039 c.231A>G synonymous_variant 1.0 linezolid
rplC 801045 c.237A>G synonymous_variant 1.0 linezolid
rplC 801054 c.246G>C synonymous_variant 1.0 linezolid
rplC 801057 c.249G>A synonymous_variant 1.0 linezolid
rplC 801063 c.255G>C synonymous_variant 1.0 linezolid
rplC 801070 p.Asp88Asn missense_variant 1.0 linezolid
rplC 801073 p.Ser89Pro missense_variant 1.0 linezolid
rplC 801078 c.270T>C synonymous_variant 1.0 linezolid
rplC 801081 c.273C>G synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801084 c.276G>T synonymous_variant 1.0 linezolid
rplC 801085 p.Thr93Ala missense_variant 1.0 linezolid Uncertain significance
rplC 801094 p.Gln96Glu missense_variant 1.0 linezolid
rplC 801099 c.291T>C synonymous_variant 1.0 linezolid
rplC 801102 c.294G>C synonymous_variant 1.0 linezolid
rplC 801105 c.297A>G synonymous_variant 1.0 linezolid
rplC 801109 c.301T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801114 c.306C>G synonymous_variant 0.94 linezolid
rplC 801117 c.309G>C synonymous_variant 1.0 linezolid
rplC 801134 p.Gly109Ala missense_variant 1.0 linezolid
rplC 801137 p.Ser110Thr missense_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801201 c.393C>T synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801315 c.507G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801400 c.592_594delGTTinsAC frameshift_variant&missense_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801432 c.624C>G synonymous_variant 1.0 linezolid
fbiC 1303165 p.Ser79Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303171 c.241A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303177 p.Ala83Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303184 p.Ser85Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303203 c.273T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303204 p.Ile92Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303217 p.Arg96His missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303227 c.297G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303242 c.312T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303248 c.318G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303268 p.Lys113Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303272 c.342A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303275 c.345C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303281 c.351A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303285 p.Ser119Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303288 p.Ser120Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303292 p.Thr121Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303297 p.Met123Leu missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303332 c.402A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303335 c.405T>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303342 p.Phe138Leu missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303359 c.429G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303368 c.438T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303374 c.444T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303425 c.495G>A synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303431 c.501T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303437 c.507C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303449 c.519C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303501 c.571C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303806 c.876G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303809 c.879G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303821 c.891C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 0.99 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303965 c.1035G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303969 p.Val347Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303989 c.1059C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 0.96 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304064 c.1134G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304070 c.1140C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304096 p.Val389Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>C synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304199 c.1269C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304913 c.1983G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304949 c.2019C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305090 c.2160C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305114 p.Asp728Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305201 c.2271G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305228 c.2298C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364667 c.255T>C synonymous_variant 1.0 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 1.0 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364766 c.354C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364772 c.360G>T synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364796 c.384G>A synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364805 c.393C>T synonymous_variant 1.0 pyrazinamide
sigE 1364808 c.396C>T synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364838 c.426C>T synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364910 c.498G>C synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.94 pyrazinamide
sigE 1364958 c.546G>T synonymous_variant 0.94 pyrazinamide
sigE 1364961 c.549A>T synonymous_variant 0.94 pyrazinamide
sigE 1364962 c.550_552delCCTinsGC frameshift_variant&missense_variant 0.94 pyrazinamide Uncertain significance
sigE 1364968 c.556C>T synonymous_variant 0.94 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 0.94 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.94 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1365006 c.594T>C synonymous_variant 0.97 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.97 pyrazinamide
sigE 1365015 c.603G>T synonymous_variant 0.97 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.95 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.95 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.94 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.9 pyrazinamide
atpE 1460813 c.-232C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460828 c.-217C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460832 c.-213C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460837 c.-208C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1461068 c.24C>T synonymous_variant 0.9 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 0.92 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.92 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.93 bedaquiline
atpE 1461119 c.75T>C synonymous_variant 0.94 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.97 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.97 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.97 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.97 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.97 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.97 bedaquiline Uncertain significance
atpE 1461182 c.138A>G synonymous_variant 0.97 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.94 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 0.97 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.97 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 0.91 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.95 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.95 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.94 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.92 bedaquiline
atpE 1461261 c.217C>T synonymous_variant 0.92 bedaquiline
rrs 1471508 n.-338T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471514 n.-332A>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473417 n.-241C>T upstream_gene_variant 0.95 capreomycin
linezolid
rrl 1473419 n.-239T>C upstream_gene_variant 0.95 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.9 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.93 capreomycin
linezolid
rrl 1473439 n.-219T>C upstream_gene_variant 0.92 capreomycin
linezolid
rrl