TB-Profiler result

Run: ERR3797017
Summary

Run ID: ERR3797017

Sample name:

Date: 2024-04-16T12:23:48.284884

Number of reads: 989068

Percentage reads mapped: 35.83

Median coverage: 44.0

Strain: La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.2.2.1 Euro-American None 0.06
lineage4.3.2.1 Euro-American (LAM) RD761 0.07
lineage4.6.4 Euro-American None 0.15
lineage3.1.2.2 East-African-Indian RD750 0.14
lineage4 Euro-American None 0.68
lineage2.1 East-Asian (non-Beijing) None 0.09
lineage4.8.1 Euro-American (mainly T) RD219 0.08
lineage4.9 Euro-American (H37Rv-like) None 0.8
La1.7.1 M.bovis None 0.13
La3 M.orygis None 0.2
La1.6 M.bovis None 0.14
M.canetti M.canetti None 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.496_498delGTTinsAC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine pepQ c.592_594delGCCinsCG Assoc w R - Interim
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.289_291delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.391_393delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiD c.196_198delGAAinsAG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA c.598_600delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.607_609delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.772_774delACGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.391_393delACCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1051_1053delATGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline pepQ c.592_594delGCCinsCG Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303219 c.289_291delTTAinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303321 c.391_393delGTTinsAC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsAG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
katG 2155614 c.496_498delGTTinsAC frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
pepQ 2859825 c.592_594delGCCinsCG frameshift_variant&synonymous_variant 0.95 clofazimine Assoc w R - Interim
bedaquiline Assoc w R - Interim Includes data from one site that only submitted resistant strains, which may have inflated the PPV
fbiD 3339313 c.196_198delGAAinsAG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641140 c.598_600delATCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641149 c.607_609delCTGinsAC frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiA 3641314 c.772_774delACGinsGC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3641925 c.391_393delACCinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642585 c.1051_1053delATGinsTC frameshift_variant&missense_variant 0.85 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 0.98 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.88 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.89 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.82 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 558 c.558G>T synonymous_variant 1.0 isoniazid
dnaA 561 c.561C>T synonymous_variant 1.0 isoniazid
dnaA 567 c.567C>T synonymous_variant 1.0 isoniazid
dnaA 570 c.570C>G synonymous_variant 1.0 isoniazid
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 588 c.588A>G synonymous_variant 1.0 isoniazid
dnaA 591 c.591C>G synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>T synonymous_variant 1.0 isoniazid
dnaA 624 c.624C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 633 c.633T>A synonymous_variant 1.0 isoniazid
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 639 c.639C>T synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 771 c.771A>C synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 804 c.804G>A synonymous_variant 1.0 isoniazid
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 834 c.834C>T synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 843 c.843T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 909 c.909A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>A synonymous_variant 1.0 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 1.0 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 1.0 isoniazid
dnaA 1051 c.1051_1053delCTCinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 1.0 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1125 c.1125G>T synonymous_variant 1.0 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 1.0 isoniazid
dnaA 1149 c.1149C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1210 p.Ala404Ser missense_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.96 isoniazid
dnaA 1314 c.1314A>C synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1335 c.1335G>A synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 1.0 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1359 c.1359G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1368 c.1368T>C synonymous_variant 1.0 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 1.0 isoniazid
dnaA 1377 c.1377G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1395 c.1395G>A synonymous_variant 1.0 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 1.0 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1461 c.1461C>A synonymous_variant 1.0 isoniazid
gyrB 6022 c.783G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6025 c.786A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6034 c.795C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6037 c.798C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6047 p.Ala270Pro missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6055 c.816T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6057 p.Ser273Asn missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6070 c.831C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6073 c.834T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6084 c.846delC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6091 c.853dupC frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6121 c.882C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6229 c.990G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6247 c.1008G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6250 c.1011A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6262 c.1023G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6313 c.-989C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6316 c.-986G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6337 c.1098G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6355 c.-947G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6685 c.1446C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6772 c.1533C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6805 c.1566G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6850 c.-452C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6901 c.-401G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6902 c.1663_1665delCTCinsTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6913 c.1674C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6943 c.-359G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861_1863delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7559 c.258G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7565 c.264C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7577 c.276C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7880 c.579C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8321 c.1020C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8438 c.1137C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8468 c.1167C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8537 c.1236G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8573 c.1272G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8595 p.Ala432Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8618 c.1317G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8633 c.1332C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8637 c.1336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8684 c.1383G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8738 c.1437G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8954 c.1653G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8965 c.1664_1665insG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8968 c.1668delG frameshift_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9131 c.1830G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9134 c.1833C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9188 c.1887C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9218 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9257 c.1956C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9276 c.1975C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9300 c.1999_2001delGCCinsTG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9344 c.2043C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
Rv0010c 13852 c.-294A>G upstream_gene_variant 0.85 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 0.87 isoniazid
Rv0010c 13864 c.-306A>G upstream_gene_variant 0.88 isoniazid
Rv0010c 13876 c.-318G>C upstream_gene_variant 0.88 isoniazid
Rv0010c 13879 c.-321T>C upstream_gene_variant 0.88 isoniazid
Rv0010c 13885 c.-327C>T upstream_gene_variant 0.88 isoniazid
Rv0010c 13891 c.-334_-333delCGinsGT upstream_gene_variant 0.88 isoniazid
Rv0010c 13894 c.-336C>G upstream_gene_variant 0.88 isoniazid
Rv0010c 13903 c.-347_-345delGTAinsAT upstream_gene_variant 0.88 isoniazid
Rv0010c 13906 c.-348C>T upstream_gene_variant 0.88 isoniazid
fgd1 490734 c.-49A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490744 c.-39T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490756 c.-27_-23delTTTATinsAC upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490764 c.-19delAinsGAATC upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490777 c.-6G>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490781 c.-2T>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490794 c.12G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490797 c.15G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490800 c.18A>C synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490806 c.24C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490812 c.30A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490815 c.33G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490926 c.144C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491022 c.240C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491031 c.249C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491038 p.Ile86Val missense_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491137 p.Glu119Gln missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491169 c.387C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491219 p.Asp146Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491229 c.447C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491391 c.609C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491393 p.Thr204Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491397 p.Glu205Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491415 c.633A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491418 c.636A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491421 c.639A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491430 c.648T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491436 c.654T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491442 c.660A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491443 p.Ser221Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491453 p.Gly224Asp missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491472 c.690A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491517 c.735C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491559 c.777G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491574 c.792C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491583 c.801G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491686 p.Thr302Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491700 c.918C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574640 c.-708G>A upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574664 c.-684G>C upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 0.91 ethionamide
isoniazid
mshA 574679 c.-669C>T upstream_gene_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574683 c.-665T>C upstream_gene_variant 0.93 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.96 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 574742 c.-606G>A upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 574763 c.-585T>C upstream_gene_variant 0.94 ethionamide
isoniazid Uncertain significance
mshA 574782 c.-566C>G upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574792 c.-556_-555delTCinsCG upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 574794 c.-554C>T upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574799 c.-549T>C upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574802 c.-546A>G upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574803 c.-545A>C upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 574814 c.-534T>C upstream_gene_variant 0.83 ethionamide
isoniazid
mshA 574835 c.-513T>C upstream_gene_variant 0.83 ethionamide
isoniazid Uncertain significance
mshA 574970 c.-378A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574979 c.-369G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575000 c.-348C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575003 c.-345G>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575011 c.-337G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575021 c.-327G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575022 c.-326C>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575030 c.-318T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575034 c.-314_-312delTTAinsAG upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575042 c.-306T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575051 c.-297A>G upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575060 c.-288G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575063 c.-285T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575072 c.-276G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575084 c.-264T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575087 c.-261C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575102 c.-246G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575521 c.174A>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575530 c.183C>A synonymous_variant 0.94 ethionamide
isoniazid
mshA 575536 c.189T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575542 c.195C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575560 c.213C>T synonymous_variant 0.97 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 0.97 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.97 ethionamide
isoniazid
mshA 575587 c.240C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575590 c.243T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575641 c.294A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575649 p.Val101Glu missense_variant 0.97 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.98 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.98 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575786 p.Tyr147His missense_variant 0.98 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575824 c.477T>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575875 c.528C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
mshA 575977 c.630G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575992 c.645C>T synonymous_variant 0.96 ethionamide
isoniazid
mshA 576001 c.654C>T synonymous_variant 0.95 ethionamide
isoniazid
mshA 576007 c.660A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 576012 p.Arg222Lys missense_variant 0.93 ethionamide
isoniazid
mshA 576017 p.Val224Leu missense_variant 0.93 ethionamide
isoniazid
mshA 576026 c.679_681delCTTinsAC frameshift_variant&missense_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576032 p.Gly229His missense_variant 0.92 ethionamide
isoniazid
mshA 576046 c.699A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576049 c.702A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576070 c.723T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 576077 c.730C>T synonymous_variant 0.95 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R
mshA 576097 c.750T>C synonymous_variant 0.93 ethionamide
isoniazid
ccsA 620133 c.243G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620139 c.249C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620145 c.255T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620167 p.Ala93Thr missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620170 p.Cys94Ser missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620187 c.297C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620198 p.Gln103Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Leu missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620269 p.Val127Ile missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620275 c.385C>T synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>A synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620409 c.519C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.95 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620448 c.558C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620454 c.564C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620460 c.570T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620461 c.571_573delGTCinsAT frameshift_variant&missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620481 c.591T>G synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620483 p.Val198Ala missense_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620659 c.769_771delCGCinsAG frameshift_variant&missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620664 c.774C>T synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAG frameshift_variant&missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620769 c.879C>G synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620778 c.888T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 0.96 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620829 c.939G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
Rv0565c 656052 c.1419A>C synonymous_variant 1.0 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656076 c.1395C>T synonymous_variant 1.0 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 1.0 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 1.0 ethionamide
Rv0565c 656091 c.1380T>C synonymous_variant 1.0 ethionamide
Rv0565c 656100 c.1371G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656115 c.1356G>A synonymous_variant 1.0 ethionamide
Rv0565c 656127 c.1342_1344delTACinsCT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656131 p.Pro447Leu missense_variant 1.0 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 1.0 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 1.0 ethionamide
Rv0565c 656145 c.1326T>C synonymous_variant 1.0 ethionamide
Rv0565c 656172 c.1299A>G synonymous_variant 1.0 ethionamide
Rv0565c 656175 c.1296G>A synonymous_variant 1.0 ethionamide
Rv0565c 656179 p.Asp431Pro missense_variant 1.0 ethionamide
Rv0565c 656238 c.1233A>G synonymous_variant 1.0 ethionamide
Rv0565c 656244 c.1227A>G synonymous_variant 1.0 ethionamide
Rv0565c 656247 c.1224A>G synonymous_variant 1.0 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 1.0 ethionamide
Rv0565c 656282 c.1189C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656304 c.1167T>C synonymous_variant 1.0 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656364 c.1107T>C synonymous_variant 1.0 ethionamide
Rv0565c 656367 c.1104G>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656370 c.1101T>C synonymous_variant 1.0 ethionamide
Rv0565c 656380 p.Glu364Gly missense_variant 1.0 ethionamide
Rv0565c 656391 c.1078_1080delCTCinsAG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656396 p.Ser359Gly missense_variant 1.0 ethionamide
Rv0565c 656403 c.1068C>G synonymous_variant 1.0 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 1.0 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 1.0 ethionamide
Rv0565c 656423 c.1048T>C synonymous_variant 1.0 ethionamide
Rv0565c 656447 p.Ile342Val missense_variant 1.0 ethionamide
Rv0565c 656448 c.1023T>C synonymous_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 1.0 ethionamide
Rv0565c 656476 p.Lys332Ala missense_variant 1.0 ethionamide
Rv0565c 656481 c.990A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656502 c.969C>T synonymous_variant 1.0 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656539 p.Ser311Asp missense_variant 1.0 ethionamide
Rv0565c 656542 p.Thr310Ser missense_variant 1.0 ethionamide
Rv0565c 656546 p.Ile309Val missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656568 c.903G>C synonymous_variant 1.0 ethionamide
Rv0565c 656582 p.Leu297Met missense_variant 1.0 ethionamide
Rv0565c 656583 c.888A>G synonymous_variant 1.0 ethionamide
Rv0565c 656589 c.882T>C synonymous_variant 1.0 ethionamide
Rv0565c 656804 p.Ser223Gly missense_variant 1.0 ethionamide
Rv0565c 656814 c.657A>G synonymous_variant 1.0 ethionamide
Rv0565c 656822 p.Ile217Val missense_variant 1.0 ethionamide
Rv0565c 656823 c.648G>C synonymous_variant 1.0 ethionamide
Rv0565c 656826 c.645C>T synonymous_variant 1.0 ethionamide
Rv0565c 656835 c.636C>G synonymous_variant 1.0 ethionamide
Rv0565c 656838 c.633A>C synonymous_variant 1.0 ethionamide
Rv0565c 656853 c.618A>G synonymous_variant 1.0 ethionamide
Rv0565c 656856 c.615G>A synonymous_variant 1.0 ethionamide
Rv0565c 656860 p.Glu204Ala missense_variant 1.0 ethionamide
Rv0565c 656865 c.606G>C synonymous_variant 1.0 ethionamide
Rv0565c 656869 p.Asp201Arg missense_variant 1.0 ethionamide
Rv0565c 656871 c.598_600delACCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656880 c.591C>G synonymous_variant 1.0 ethionamide
Rv0565c 656889 c.582A>G synonymous_variant 1.0 ethionamide
Rv0565c 656901 c.570C>G synonymous_variant 1.0 ethionamide
Rv0565c 656924 p.Ile183Val missense_variant 1.0 ethionamide
Rv0565c 656926 p.Lys182Arg missense_variant 1.0 ethionamide
Rv0565c 656946 p.Asp175Gly missense_variant 1.0 ethionamide
Rv0565c 656949 c.522G>A synonymous_variant 1.0 ethionamide
Rv0565c 656952 c.519A>G synonymous_variant 1.0 ethionamide
Rv0565c 656973 c.498A>C synonymous_variant 1.0 ethionamide
Rv0565c 656976 c.493_495delGCGinsAC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656985 c.486T>C synonymous_variant 1.0 ethionamide
Rv0565c 656991 c.480G>A synonymous_variant 1.0 ethionamide
Rv0565c 656997 c.474C>G synonymous_variant 1.0 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 1.0 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 1.0 ethionamide
Rv0565c 657043 p.Ser143Thr missense_variant 1.0 ethionamide
Rv0565c 657046 p.Gly142Ala missense_variant 1.0 ethionamide
Rv0565c 657220 p.Ala84Val missense_variant 1.0 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 1.0 ethionamide
Rv0565c 657234 c.237C>A synonymous_variant 1.0 ethionamide
Rv0565c 657241 p.Glu77Arg missense_variant 1.0 ethionamide
Rv0565c 657243 c.228C>G synonymous_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657317 c.154C>T synonymous_variant 1.0 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 1.0 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 1.0 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 1.0 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 1.0 ethionamide
Rv0565c 657369 c.100_102delCAGinsGC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657381 c.90A>G synonymous_variant 1.0 ethionamide
Rv0565c 657385 p.Ile29Ser missense_variant 1.0 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 1.0 ethionamide
Rv0565c 657405 c.64_66delCTGinsAT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657408 c.63A>C synonymous_variant 1.0 ethionamide
Rv0565c 657417 c.54C>T synonymous_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731747 c.-183T>C upstream_gene_variant 0.95 isoniazid
hadA 731748 c.-182_-180delTTGinsCC upstream_gene_variant 0.95 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.94 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.94 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.94 isoniazid
hadA 731816 c.-114G>C upstream_gene_variant 0.93 isoniazid
hadA 731817 c.-113C>T upstream_gene_variant 0.93 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732060 p.Gly44Ala missense_variant 1.0 isoniazid
hadA 732064 c.135C>G synonymous_variant 1.0 isoniazid
hadA 732070 c.141A>G synonymous_variant 1.0 isoniazid
hadA 732076 c.147G>C synonymous_variant 1.0 isoniazid
hadA 732079 c.150T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732085 c.156C>G synonymous_variant 1.0 isoniazid
hadA 732094 c.165T>C synonymous_variant 1.0 isoniazid
hadA 732106 c.177T>C synonymous_variant 1.0 isoniazid
hadA 732130 c.201C>G synonymous_variant 1.0 isoniazid
hadA 732133 c.204G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732134 p.Ala69Ser missense_variant 1.0 isoniazid
hadA 732151 c.222T>C synonymous_variant 1.0 isoniazid
hadA 732154 c.225G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732164 p.Thr79Val missense_variant 1.0 isoniazid
hadA 732167 p.Ala80Thr missense_variant 1.0 isoniazid
hadA 732172 p.Glu81Asp missense_variant 1.0 isoniazid
hadA 732173 p.Ala82Gln missense_variant 1.0 isoniazid
hadA 732190 c.261A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732209 p.Glu94Gln missense_variant 1.0 isoniazid
hadA 732214 c.285A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732234 p.Lys102Arg missense_variant 1.0 isoniazid Uncertain significance
hadA 732238 c.309G>C synonymous_variant 1.0 isoniazid
hadA 732250 c.321C>G synonymous_variant 1.0 isoniazid
hadA 732253 c.324T>C synonymous_variant 1.0 isoniazid
hadA 732259 c.330T>C synonymous_variant 1.0 isoniazid
hadA 732279 p.Gly117Ala missense_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732319 c.390G>A synonymous_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732328 p.Asp133Glu missense_variant 1.0 isoniazid Uncertain significance
hadA 732329 c.400_402delCTCinsAT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732334 c.405G>C synonymous_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732369 p.Gly147Ala missense_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732389 p.Ser154Thr missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734076 c.-178_-176delGCCinsAG upstream_gene_variant 0.82 rifampicin
nusG 734093 c.-161A>G upstream_gene_variant 0.89 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.9 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.96 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.96 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.97 rifampicin
nusG 734156 c.-98C>T upstream_gene_variant 0.97 rifampicin Uncertain significance
nusG 734173 c.-81C>G upstream_gene_variant 0.97 rifampicin
nusG 734175 c.-79_-77delGGTinsCTC upstream_gene_variant 0.97 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734193 c.-61A>G upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734224 c.-30_-26delGCTCGinsCATTGC upstream_gene_variant 1.0 rifampicin
nusG 734233 c.-21T>C upstream_gene_variant 1.0 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 1.0 rifampicin
nusG 734274 p.Asp7Glu missense_variant 0.92 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.82 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.89 rifampicin
nusG 734409 c.156T>C synonymous_variant 0.97 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.97 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.97 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.98 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.98 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734470 c.217_219delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734566 c.313C>T synonymous_variant 0.95 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.93 rifampicin
nusG 734595 c.342C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734610 c.357C>G synonymous_variant 0.93 rifampicin
nusG 734619 c.366G>A synonymous_variant 0.93 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.94 rifampicin
nusG 734640 c.387C>T synonymous_variant 0.89 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.88 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.85 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734658 c.405A>G synonymous_variant 0.84 rifampicin Not assoc w R
nusG 734661 c.408A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
nusG 734664 c.411T>G synonymous_variant 0.84 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.84 rifampicin
nusG 734676 c.423G>C synonymous_variant 0.84 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsAG frameshift_variant&missense_variant 0.89 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.95 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.95 rifampicin
nusG 734715 c.462G>T synonymous_variant 0.94 rifampicin
nusG 734717 p.Gly155Ala missense_variant 0.94 rifampicin
nusG 734719 c.466_468delTCGinsGC frameshift_variant&missense_variant 0.94 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.95 rifampicin
nusG 734733 c.480T>C synonymous_variant 0.96 rifampicin
nusG 734757 c.504T>C synonymous_variant 0.96 rifampicin
nusG 734762 p.Ala170Val missense_variant 0.95 rifampicin
nusG 734764 p.Ala171Thr missense_variant 0.96 rifampicin
nusG 734781 c.528A>G synonymous_variant 1.0 rifampicin
nusG 734784 c.531G>A synonymous_variant 1.0 rifampicin
nusG 734792 p.Val180Ala missense_variant 1.0 rifampicin
nusG 734800 p.Val183Ile missense_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.98 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.98 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.98 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.97 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.96 rifampicin
nusG 734931 c.678A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734940 c.687G>A synonymous_variant 0.94 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 0.93 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoB 759656 c.-151A>C upstream_gene_variant 0.89 rifampicin
rpoB 759657 c.-150G>T upstream_gene_variant 0.89 rifampicin
rpoB 759659 c.-148T>C upstream_gene_variant 0.89 rifampicin
rpoB 759665 c.-141delT upstream_gene_variant 0.89 rifampicin
rpoB 759671 c.-136G>T upstream_gene_variant 0.89 rifampicin
rpoB 759672 c.-135G>A upstream_gene_variant 0.89 rifampicin
rpoB 759681 c.-125_-124delGT upstream_gene_variant 0.9 rifampicin
rpoB 759715 c.-92_-91delGAinsT upstream_gene_variant 0.88 rifampicin
rpoB 759726 c.-81A>G upstream_gene_variant 0.88 rifampicin
rpoB 759732 c.-75C>T upstream_gene_variant 0.87 rifampicin
rpoB 759741 c.-66_-65insA upstream_gene_variant 0.82 rifampicin
rpoB 759748 c.-59_-58insC upstream_gene_variant 0.8 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.91 rifampicin
rpoB 760073 c.267G>C synonymous_variant 0.92 rifampicin
rpoB 760091 c.285G>T synonymous_variant 0.96 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>T synonymous_variant 0.97 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.97 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.93 rifampicin Not assoc w R
rpoB 760118 c.312T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.97 rifampicin
rpoB 760172 c.366G>C synonymous_variant 0.97 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.98 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.98 rifampicin
rpoB 760313 c.507G>C synonymous_variant 0.98 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.98 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.97 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 0.97 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760528 p.Gln241Arg missense_variant 0.98 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.98 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760716 c.910_912delCGCinsAG frameshift_variant&missense_variant 0.91 rifampicin
rpoB 760799 c.993C>T synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.94 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.95 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsGA frameshift_variant&missense_variant 0.92 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760862 c.1056G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 0.94 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.97 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.97 rifampicin
rpoB 760934 c.1128C>G synonymous_variant 0.97 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.94 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.98 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761196 c.1390C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.98 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.97 rifampicin
rpoB 761309 c.1503C>T synonymous_variant 0.96 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761336 c.1530C>T synonymous_variant 0.97 rifampicin
rpoB 761339 c.1533C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 0.91 rifampicin
rpoB 761348 c.1542C>G synonymous_variant 0.94 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.94 rifampicin
rpoB 761357 c.1551G>C synonymous_variant 0.94 rifampicin
rpoB 761362 p.Ser519Thr missense_variant 0.94 rifampicin
rpoB 761375 c.1569G>C synonymous_variant 0.94 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.89 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761505 c.1699_1701delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761540 c.1734C>G synonymous_variant 1.0 rifampicin
rpoB 761552 c.1746G>C synonymous_variant 1.0 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.98 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.98 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.98 rifampicin
rpoB 761720 c.1915_1916delGA frameshift_variant 0.98 rifampicin
rpoB 761724 p.Glu640Thr missense_variant 0.98 rifampicin
rpoB 761728 c.1923_1924insCC frameshift_variant 0.98 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.98 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.98 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761840 c.2034C>A synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762011 c.2205G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762020 c.2214G>A synonymous_variant 1.0 rifampicin
rpoB 762023 c.2217C>T synonymous_variant 1.0 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762119 c.2313C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 c.2491C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.98 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.97 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.97 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762490 p.Val895Ala missense_variant 0.96 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.94 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 0.96 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.96 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.95 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.95 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.94 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 1.0 rifampicin
rpoC 762734 c.-636G>A upstream_gene_variant 1.0 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 1.0 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 762770 c.-600C>G upstream_gene_variant 1.0 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763052 c.-318G>C upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.98 rifampicin
rpoC 763082 c.-288C>G upstream_gene_variant 0.98 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763184 c.3378C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.98 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763268 c.-102C>A upstream_gene_variant 1.0 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763430 c.61A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763537 c.168C>G synonymous_variant 1.0 rifampicin
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>G synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763648 c.279C>A synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>A synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763790 c.421_423delGAGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763816 c.447C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763871 p.Gly168Thr missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763927 c.558C>G synonymous_variant 1.0 rifampicin
rpoC 763948 c.579G>C synonymous_variant 1.0 rifampicin
rpoC 763963 c.594C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.99 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.99 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.99 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.99 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764245 c.876C>G synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764320 c.951C>G synonymous_variant 0.98 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764339 c.970C>T synonymous_variant 0.98 rifampicin
rpoC 764380 c.1011G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.95 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764429 c.1060C>T synonymous_variant 1.0 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764438 c.1069_1071delCTGinsTA frameshift_variant&stop_gained 1.0 rifampicin
rpoC 764443 c.1074C>T synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>A synonymous_variant 1.0 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>T synonymous_variant 1.0 rifampicin
rpoC 764467 c.1098C>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764533 c.1164C>G synonymous_variant 1.0 rifampicin
rpoC 764536 c.1167G>C synonymous_variant 1.0 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764551 c.1182G>C synonymous_variant 1.0 rifampicin
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 1.0 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 1.0 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 764656 c.1287C>T synonymous_variant 1.0 rifampicin
rpoC 764695 c.1326T>C synonymous_variant 0.98 rifampicin
rpoC 764749 c.1380G>C synonymous_variant 0.98 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.98 rifampicin
rpoC 764851 c.1482C>T synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489_1491delTTGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764861 c.1492C>T synonymous_variant 1.0 rifampicin
rpoC 764867 c.1498_1500delCGCinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764875 c.1506C>G synonymous_variant 1.0 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764881 c.1512G>C synonymous_variant 1.0 rifampicin
rpoC 764885 c.1516_1518delCGGinsAA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764986 c.1617C>T synonymous_variant 1.0 rifampicin
rpoC 764995 c.1626C>G synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 765006 c.1638_1642delTTTGA frameshift_variant 1.0 rifampicin
rpoC 765013 c.1644_1645insTCTCG frameshift_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>T synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 1.0 rifampicin
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765202 c.1833C>G synonymous_variant 1.0 rifampicin
rpoC 765208 c.1839T>C synonymous_variant 1.0 rifampicin
rpoC 765220 c.1851A>G synonymous_variant 1.0 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 1.0 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 1.0 rifampicin
rpoC 765247 c.1878C>T synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765307 c.1938C>T synonymous_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Thr missense_variant 1.0 rifampicin
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765346 c.1977C>G synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.99 rifampicin
rpoC 765612 p.His748Arg missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765673 p.Asp768Glu missense_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765823 c.2454C>G synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>G synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>G synonymous_variant 1.0 rifampicin
rpoC 766009 c.2640G>T synonymous_variant 1.0 rifampicin
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 1.0 rifampicin
rpoC 766054 c.2685C>T synonymous_variant 1.0 rifampicin
rpoC 766063 c.2694C>T synonymous_variant 0.98 rifampicin
rpoC 766081 c.2712T>C synonymous_variant 1.0 rifampicin
rpoC 766084 c.2715A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766085 p.Pro906Ala missense_variant 1.0 rifampicin Not assoc w R
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766168 c.2799C>G synonymous_variant 1.0 rifampicin
rpoC 766178 p.Ile937Val missense_variant 1.0 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 1.0 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 1.0 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 1.0 rifampicin
rpoC 766211 p.Glu948Ser missense_variant 1.0 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766222 c.2853T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766231 c.2862T>G synonymous_variant 1.0 rifampicin
rpoC 766234 c.2865T>G synonymous_variant 1.0 rifampicin
rpoC 766237 c.2868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766240 c.2871T>C synonymous_variant 1.0 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 1.0 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 1.0 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.97 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766285 c.2916C>G synonymous_variant 1.0 rifampicin
rpoC 766312 c.2943T>C synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.98 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.98 rifampicin
rpoC 766486 c.3117A>C synonymous_variant 0.98 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.98 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.98 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.98 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.98 rifampicin
rpoC 766531 c.3162G>T synonymous_variant 0.98 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.98 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.98 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.98 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.98 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 0.98 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.98 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.98 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766627 c.3258G>C synonymous_variant 1.0 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766658 p.Arg1097Gly missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.99 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.99 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.97 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>A synonymous_variant 0.98 rifampicin
rpoC 766864 c.3495G>C synonymous_variant 0.98 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 0.98 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 0.97 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.97 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.98 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766923 p.Glu1185Gly missense_variant 1.0 rifampicin
rpoC 766931 c.3562_3564delGCAinsTG frameshift_variant&stop_gained 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 1.0 rifampicin
rpoC 766978 c.3609C>T synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767032 c.3663G>C synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>G synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767152 c.3783T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>G synonymous_variant 0.98 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.97 rifampicin
rpoC 767188 c.3819G>A synonymous_variant 0.98 rifampicin
rpoC 767209 c.3840T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767242 p.Gln1291His missense_variant 0.95 rifampicin
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767275 c.3906T>G synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775829 c.2652C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775832 c.2647_2649delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775838 c.2643G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775847 c.2634G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775851 p.Ser877Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775985 c.2496C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777125 c.1356C>T synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 777142 p.Val447Leu missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777158 c.1323C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777163 p.Gln440Lys missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777164 c.1317C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777191 c.1290C>A synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777194 p.Glu429Ala missense_variant 0.93 clofazimine
bedaquiline
mmpL5 777200 c.1281C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 777206 c.1275A>G synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 777209 c.1272C>T synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 777251 c.1230C>A synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777254 c.1227G>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 777269 c.1212T>C synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781130 c.-430_-429delACinsGT upstream_gene_variant 1.0 streptomycin
rpsL 781137 c.-423G>C upstream_gene_variant 1.0 streptomycin
rpsL 781138 c.-422C>G upstream_gene_variant 1.0 streptomycin
rpsL 781143 c.-417T>G upstream_gene_variant 1.0 streptomycin
rpsL 781158 c.-402C>G upstream_gene_variant 1.0 streptomycin
rpsL 781161 c.-399G>A upstream_gene_variant 1.0 streptomycin
rpsL 781164 c.-396T>C upstream_gene_variant 1.0 streptomycin
rpsL 781170 c.-390G>C upstream_gene_variant 1.0 streptomycin
rpsL 781179 c.-381T>C upstream_gene_variant 1.0 streptomycin
rpsL 781182 c.-378G>T upstream_gene_variant 1.0 streptomycin
rpsL 781189 c.-371T>C upstream_gene_variant 1.0 streptomycin
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781649 c.90T>C synonymous_variant 0.98 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.98 streptomycin
rpsL 781682 c.123T>G synonymous_variant 0.99 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.99 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.99 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.99 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.97 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.99 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781820 c.261G>C synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>A upstream_gene_variant 1.0 linezolid
rplC 800555 c.-254C>T upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800576 c.-233C>T upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.98 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>G upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>A upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10_-8delGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800874 c.66A>G synonymous_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>C synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800967 c.159C>A synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800973 c.165C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 801004 p.Leu66Val missense_variant 1.0 linezolid
rplC 801009 c.201A>C synonymous_variant 1.0 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801039 c.231A>G synonymous_variant 1.0 linezolid
rplC 801045 c.237A>G synonymous_variant 1.0 linezolid
rplC 801054 c.246G>C synonymous_variant 1.0 linezolid
rplC 801057 c.249G>A synonymous_variant 1.0 linezolid
rplC 801063 c.255G>C synonymous_variant 1.0 linezolid
rplC 801070 p.Asp88Asn missense_variant 1.0 linezolid
rplC 801073 p.Ser89Pro missense_variant 1.0 linezolid
rplC 801078 c.270T>C synonymous_variant 1.0 linezolid
rplC 801081 c.273C>G synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801084 c.276G>T synonymous_variant 1.0 linezolid
rplC 801085 p.Thr93Ala missense_variant 1.0 linezolid Uncertain significance
rplC 801094 p.Gln96Glu missense_variant 1.0 linezolid
rplC 801099 c.291T>C synonymous_variant 1.0 linezolid
rplC 801102 c.294G>C synonymous_variant 1.0 linezolid
rplC 801105 c.297A>G synonymous_variant 1.0 linezolid
rplC 801109 c.301T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801114 c.306C>G synonymous_variant 0.94 linezolid
rplC 801117 c.309G>C synonymous_variant 1.0 linezolid
rplC 801134 p.Gly109Ala missense_variant 1.0 linezolid
rplC 801137 p.Ser110Thr missense_variant 1.0 linezolid
rplC 801147 c.339T>C synonymous_variant 1.0 linezolid
rplC 801153 c.345G>C synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801201 c.393C>T synonymous_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801288 c.480G>C synonymous_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801315 c.507G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 1.0 linezolid
rplC 801396 c.588T>C synonymous_variant 1.0 linezolid
rplC 801400 c.592_594delGTTinsAC frameshift_variant&missense_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801426 c.618C>G synonymous_variant 1.0 linezolid
rplC 801432 c.624C>G synonymous_variant 1.0 linezolid
fbiC 1303165 p.Ser79Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303171 c.241A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303177 p.Ala83Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303184 p.Ser85Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303203 c.273T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303204 p.Ile92Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303217 p.Arg96His missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303227 c.297G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303242 c.312T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303248 c.318G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303268 p.Lys113Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303272 c.342A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303275 c.345C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303281 c.351A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303285 p.Ser119Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303288 p.Ser120Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303292 p.Thr121Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303297 p.Met123Leu missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303332 c.402A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303335 c.405T>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303342 p.Phe138Leu missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303359 c.429G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303368 c.438T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303374 c.444T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303425 c.495G>A synonymous_variant 0.9 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303431 c.501T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303437 c.507C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303449 c.519C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303455 c.525C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303480 p.Gln184Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303501 c.571C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303623 c.693C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Pro missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303789 p.Ile287Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303806 c.876G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303809 c.879G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303821 c.891C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 0.99 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303884 c.954T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303935 c.1005G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303965 c.1035G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303969 p.Val347Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303989 c.1059C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304058 p.Glu376Asp missense_variant 0.96 clofazimine
pretomanid
delamanid Uncertain significance
fbiC 1304064 c.1134G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304070 c.1140C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304096 p.Val389Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>C synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304199 c.1269C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304232 c.1302G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304637 c.1707G>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Glu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304853 c.1923C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.99 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304913 c.1983G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304949 c.2019C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304970 c.2040G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304995 c.2065T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305066 c.2136T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305069 c.2139G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305074 p.Ser715Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305078 c.2148A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305090 c.2160C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305096 c.2166T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305099 c.2169T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305114 p.Asp728Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305150 c.2220C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305154 c.2224T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305159 c.2229G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1305177 c.2247A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305181 c.2251T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305186 c.2256C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1305195 c.2265T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305201 c.2271G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305204 c.2274C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305215 p.Ser762Thr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305228 c.2298C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305231 c.2301C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305237 c.2307A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305240 c.2310T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305243 c.2313T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305244 c.2314T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305273 c.2343C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305276 c.2346G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305282 c.2352T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305297 c.2367G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364667 c.255T>C synonymous_variant 1.0 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 1.0 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364766 c.354C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364772 c.360G>T synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364796 c.384G>A synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364805 c.393C>T synonymous_variant 1.0 pyrazinamide
sigE 1364808 c.396C>T synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364838 c.426C>T synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364910 c.498G>C synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.94 pyrazinamide
sigE 1364958 c.546G>T synonymous_variant 0.94 pyrazinamide
sigE 1364961 c.549A>T synonymous_variant 0.94 pyrazinamide
sigE 1364962 c.550_552delCCTinsGC frameshift_variant&missense_variant 0.94 pyrazinamide Uncertain significance
sigE 1364968 c.556C>T synonymous_variant 0.94 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 0.94 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.94 pyrazinamide
sigE 1364989 c.577C>T synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1365006 c.594T>C synonymous_variant 0.97 pyrazinamide
sigE 1365012 c.600G>C synonymous_variant 0.97 pyrazinamide
sigE 1365015 c.603G>T synonymous_variant 0.97 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.95 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.95 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.94 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.9 pyrazinamide
atpE 1460813 c.-232C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460828 c.-217C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460832 c.-213C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460837 c.-208C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1461068 c.24C>T synonymous_variant 0.9 bedaquiline
atpE 1461097 p.Ala18Gly missense_variant 0.92 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.92 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.93 bedaquiline
atpE 1461119 c.75T>C synonymous_variant 0.94 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.97 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.97 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.97 bedaquiline
atpE 1461150 c.106_108delATCinsGT frameshift_variant&missense_variant 0.97 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.97 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.97 bedaquiline Uncertain significance
atpE 1461182 c.138A>G synonymous_variant 0.97 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.94 bedaquiline
atpE 1461189 c.145C>T synonymous_variant 0.97 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 0.97 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 0.91 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.95 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.95 bedaquiline
atpE 1461233 c.189A>C synonymous_variant 0.94 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.92 bedaquiline
atpE 1461261 c.217C>T synonymous_variant 0.92 bedaquiline
rrs 1471508 n.-338T>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471514 n.-332A>C upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473417 n.-241C>T upstream_gene_variant 0.95 capreomycin
linezolid
rrl 1473419 n.-239T>C upstream_gene_variant 0.95 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.9 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.93 capreomycin
linezolid
rrl 1473439 n.-219T>C upstream_gene_variant 0.92 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474040 n.383G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474060 n.403G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474289 n.632C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474292 n.635T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474293 n.637_651delCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474414 n.757C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474415 n.758C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474416 n.761_784delCACGCGCATACGCGCGTGTGAATA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474997 n.1340A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475253 n.1596T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475273 n.1616T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475289 n.1632G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475409 n.1752T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475626 n.1969T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475639 n.1982C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475655 n.1998T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1674199 c.-3C>G upstream_gene_variant 0.91 ethionamide
isoniazid Uncertain significance
inhA 1674205 p.Thr2Ala missense_variant 0.93 ethionamide
isoniazid Uncertain significance
inhA 1674216 c.15G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674219 p.Asp6Glu missense_variant 0.95 ethionamide
isoniazid
inhA 1674225 c.24A>G synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674237 c.36T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674239 p.Ser13Thr missense_variant 0.96 ethionamide
isoniazid
inhA 1674243 c.42A>G synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674249 c.48C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674279 c.78A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674285 c.84A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674300 c.99C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674304 c.103_105delCAGinsGA frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674315 c.114C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 1.0 ethionamide Uncertain significance
isoniazid
inhA 1674364 c.164_165dupCG frameshift_variant 1.0 ethionamide
isoniazid
inhA 1674368 c.169_170delAA frameshift_variant 1.0 ethionamide
isoniazid
inhA 1674387 c.186A>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674406 p.Glu69Lys missense_variant 1.0 ethionamide
isoniazid
inhA 1674416 p.Ala72Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1674419 p.Ser73Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674421 c.220_222delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674425 p.Ala75Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674428 p.Gly76Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674443 p.Ala81Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674450 c.249G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674503 p.Thr101Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674628 p.Ser143Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674663 c.462G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674765 c.564C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>A synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674825 c.624C>T synonymous_variant 0.98 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674846 c.645C>A synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674849 p.Gln216His missense_variant 0.98 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674883 c.682_684delATCinsCG frameshift_variant&missense_variant 0.97 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 0.97 ethionamide
isoniazid
inhA 1674933 c.732G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674939 c.738G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674945 p.Asp248Glu missense_variant 0.97 ethionamide
isoniazid
inhA 1674957 c.756G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674970 p.Ile257Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 1.0 ethionamide
isoniazid
rpsA 1833256 c.-286C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833265 c.-277A>G upstream_gene_variant 0.96 pyrazinamide
rpsA 1833268 c.-274C>G upstream_gene_variant 0.96 pyrazinamide
rpsA 1833271 c.-271G>A upstream_gene_variant 0.91 pyrazinamide
rpsA 1833273 c.-269G>A upstream_gene_variant 0.95 pyrazinamide
rpsA 1833280 c.-262G>A upstream_gene_variant 0.95 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 0.95 pyrazinamide
rpsA 1833295 c.-247C>G upstream_gene_variant 0.94 pyrazinamide
rpsA 1833517 c.-24delC upstream_gene_variant 0.93 pyrazinamide
rpsA 1833541 c.-1T>C upstream_gene_variant 0.97 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.98 pyrazinamide Uncertain significance
rpsA 1833578 p.Val13Ile missense_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833673 c.132C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834051 c.510G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834183 c.642T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834192 c.651C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGT synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834411 c.870T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834432 c.891G>A synonymous_variant 0.99 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834788 p.Ala416Gly missense_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834852 c.1311C>G synonymous_variant 1.0 pyrazinamide
tsnR 1853360 c.-246G>A upstream_gene_variant 0.98 linezolid
tsnR 1853361 c.-245T>C upstream_gene_variant 0.98 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.98 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 0.98 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.98 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.98 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 1.0 linezolid
tsnR 1853447 c.-159C>A upstream_gene_variant 1.0 linezolid
tsnR 1853450 c.-156G>C upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 1.0 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 1.0 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.96 linezolid
tsnR 1853492 c.-114G>C upstream_gene_variant 0.96 linezolid
tsnR 1853498 c.-108G>A upstream_gene_variant 1.0 linezolid
tsnR 1853504 c.-102C>G upstream_gene_variant 0.94 linezolid
tsnR 1853510 c.-96G>C upstream_gene_variant 0.93 linezolid
tsnR 1853515 c.-91A>G upstream_gene_variant 0.92 linezolid
tsnR 1853540 c.-66A>G upstream_gene_variant 0.91 linezolid
tsnR 1853923 c.318A>G synonymous_variant 1.0 linezolid
tsnR 1853928 p.Gln108Arg missense_variant 1.0 linezolid
tsnR 1853941 c.336G>C synonymous_variant 1.0 linezolid
tsnR 1853942 p.Thr113Ala missense_variant 1.0 linezolid
tsnR 1853954 p.Arg117Gly missense_variant 1.0 linezolid
tsnR 1853968 c.363C>T synonymous_variant 0.96 linezolid
tsnR 1853971 c.366G>C synonymous_variant 0.96 linezolid
tsnR 1853978 c.373_375delGTAinsCG frameshift_variant&missense_variant 0.96 linezolid Uncertain significance
tsnR 1854004 c.399T>C synonymous_variant 0.97 linezolid
tsnR 1854007 c.402C>G synonymous_variant 0.97 linezolid
tsnR 1854024 p.Ala140Gly missense_variant 0.97 linezolid
tsnR 1854030 p.Arg142His missense_variant 0.97 linezolid
tsnR 1854034 c.429C>T synonymous_variant 0.97 linezolid
tsnR 1854043 c.438A>G synonymous_variant 0.96 linezolid
tsnR 1854058 c.453T>C synonymous_variant 0.94 linezolid
bacA 2064159 c.570A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064165 c.564T>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064189 c.540G>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064192 c.535_537delGAAinsAC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064207 c.522C>T synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064210 c.519A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064223 p.Arg169Lys missense_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
bacA 2064240 c.487_489delCAAinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064243 c.486A>C synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064251 p.His160Asn missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064253 p.His159Ala missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064258 c.471A>G synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064267 c.460_462delAGGinsCC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
bacA 2064281 p.Ile150Val missense_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064285 c.444C>A synonymous_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064909 c.-181C>T upstream_gene_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064915 c.-187G>C upstream_gene_variant 0.87 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064927 c.-199G>C upstream_gene_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064932 c.-204C>T upstream_gene_variant 0.91 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 0.92 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064952 c.-224T>C upstream_gene_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064969 c.-241T>C upstream_gene_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-253_-251delGGCinsCT upstream_gene_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
bacA 2065005 c.-277C>T upstream_gene_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101711 c.1332G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101726 c.1317A>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101732 c.1311T>C synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2101735 c.1308A>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>G synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>C synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.97 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>C synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2101795 c.1248G>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101838 p.Ala402Val missense_variant 0.98 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101888 c.1153_1155delGTTinsCG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101891 c.1152C>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101912 c.1131G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101920 c.1123A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101936 c.1107G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101970 p.Glu358Ala missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101980 p.Asn355Asp missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101984 c.1059C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101988 p.Ala352Gly missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2101990 c.1053G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102009 p.Ser345Asn missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102020 c.1023A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102023 c.1020G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102026 c.1017G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102050 c.993T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102059 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102065 c.978G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102068 c.975T>C synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2102077 c.966T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102083 c.960G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102086 c.957G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102098 c.945G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102101 c.940_942delTACinsCT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102110 c.931_933delATTinsGC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102122 c.921C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102131 c.910_912delCAAinsAG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102140 c.903C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102158 c.885T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102162 p.Arg294Ser missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102164 c.879A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102167 c.876A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102176 c.867T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102193 p.Arg284Gly missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102194 c.849T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102201 p.Ser281Gln missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102203 c.840T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102206 c.837G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102209 c.834C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102212 c.831G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102221 c.822G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102230 c.813G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102247 p.Val266Ile missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102269 c.774C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102287 c.756C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102311 c.732G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102317 c.726A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102320 c.723G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102341 c.702C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102344 c.699T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102366 p.Ala226Glu missense_variant 0.99 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102377 c.666A>G synonymous_variant 0.99 ethionamide
delamanid
isoniazid
ndh 2102382 c.661C>T synonymous_variant 0.98 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102389 c.654G>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2102392 c.651C>G synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2102401 c.642T>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102407 c.636T>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2102425 c.618G>C synonymous_variant 0.98 ethionamide
delamanid
isoniazid
ndh 2102443 c.600A>G synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2102446 c.597C>T synonymous_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2102454 c.589T>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102455 c.588G>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102461 c.582G>A synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102469 c.574C>T synonymous_variant 0.95 ethionamide
delamanid
isoniazid
ndh 2102482 c.561A>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102581 c.462T>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102593 c.450C>G synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102610 c.433T>C synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2102623 c.420C>G synonymous_variant 0.83 ethionamide
delamanid
isoniazid
ndh 2102626 c.417G>A synonymous_variant 0.83 ethionamide
delamanid
isoniazid
ndh 2102635 c.408C>G synonymous_variant 0.83 ethionamide
delamanid
isoniazid
ndh 2102638 c.405A>G synonymous_variant 0.83 ethionamide
delamanid
isoniazid
ndh 2102653 c.390T>C synonymous_variant 0.89 ethionamide
delamanid
isoniazid
ndh 2102668 c.375T>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102712 p.Pro111Ser missense_variant 0.97 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102737 p.Glu102Asp missense_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102740 c.303G>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102743 c.300C>G synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102746 c.297C>G synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102750 p.Cys98Thr missense_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102755 p.Gly96Asn missense_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102771 p.His91Gly missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102787 c.256T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102791 c.252A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102800 c.243T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102809 c.234G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102812 c.231T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102830 c.213G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102842 c.201A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102857 c.186T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102872 c.171A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102883 c.160C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102884 c.159G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102893 c.150G>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102919 c.124C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102934 p.Asp37Asn missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102938 p.Arg35His missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102944 c.99C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
katG 2155590 c.522A>G synonymous_variant 0.91 isoniazid
katG 2155596 c.516G>C synonymous_variant 0.92 isoniazid
katG 2155617 c.495T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155632 c.480A>C synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155676 c.436C>A synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155696 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155704 c.408C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>C synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
pncA 2289858 c.-617G>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289871 c.-630T>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289874 c.-633C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289880 c.-639T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289907 c.-666A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289913 c.-672T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2289916 c.-675A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289920 c.-679C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289928 c.-687C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289940 c.-699C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 1.0 pyrazinamide
pncA 2289949 c.-708A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289961 c.-720C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289964 c.-723C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289970 c.-729C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.98 pyrazinamide
pncA 2290006 c.-765T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290009 c.-768A>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 1.0 pyrazinamide
pncA 2290034 c.-794_-793delGCinsAG upstream_gene_variant 0.98 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290072 c.-831T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290075 c.-834C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290084 c.-843T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290087 c.-846T>C upstream_gene_variant 1.0 pyrazinamide
pncA 2290102 c.-861G>A upstream_gene_variant 1.0 pyrazinamide
pncA 2290108 c.-867C>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290114 c.-873T>G upstream_gene_variant 1.0 pyrazinamide
pncA 2290120 c.-881_-879delAATinsGC upstream_gene_variant 1.0 pyrazinamide
pncA 2290129 c.-888C>T upstream_gene_variant 1.0 pyrazinamide
kasA 2517920 c.-195G>A upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2518156 c.42T>C synonymous_variant 1.0 isoniazid
kasA 2518162 c.48G>A synonymous_variant 1.0 isoniazid
kasA 2518172 c.58_60delACAinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 1.0 isoniazid
kasA 2518195 c.81G>A synonymous_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518226 p.Ala38Ser missense_variant 1.0 isoniazid
kasA 2518245 p.His44Arg missense_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518279 c.165T>C synonymous_variant 1.0 isoniazid
kasA 2518282 c.168A>G synonymous_variant 1.0 isoniazid
kasA 2518283 c.169_171delGCGinsCC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518297 c.183C>T synonymous_variant 1.0 isoniazid
kasA 2518300 c.186T>A synonymous_variant 1.0 isoniazid
kasA 2518312 p.Asp66Glu missense_variant 1.0 isoniazid
kasA 2518316 p.Val68Ile missense_variant 1.0 isoniazid
kasA 2518323 p.Ser70Asn missense_variant 1.0 isoniazid
kasA 2518336 c.222A>G synonymous_variant 1.0 isoniazid
kasA 2518339 c.225C>G synonymous_variant 1.0 isoniazid
kasA 2518343 p.Met77Leu missense_variant 1.0 isoniazid
kasA 2518348 c.234A>G synonymous_variant 1.0 isoniazid
kasA 2518369 c.255G>C synonymous_variant 1.0 isoniazid
kasA 2518370 p.Met86Leu missense_variant 1.0 isoniazid
kasA 2518374 p.Gly87Ala missense_variant 1.0 isoniazid
kasA 2518378 c.264G>A synonymous_variant 1.0 isoniazid
kasA 2518381 p.Leu89Phe missense_variant 1.0 isoniazid
kasA 2518385 p.Gly91Ser missense_variant 1.0 isoniazid
kasA 2518390 c.276A>C synonymous_variant 1.0 isoniazid
kasA 2518396 c.282A>G synonymous_variant 1.0 isoniazid
kasA 2518403 c.289_291delTCCinsGG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518408 c.294C>G synonymous_variant 1.0 isoniazid
kasA 2518417 c.303G>C synonymous_variant 1.0 isoniazid
kasA 2518429 c.315A>G synonymous_variant 1.0 isoniazid
kasA 2518435 c.321G>C synonymous_variant 1.0 isoniazid
kasA 2518439 c.325_327delGCCinsTG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518444 c.330T>C synonymous_variant 1.0 isoniazid
kasA 2518447 c.333T>G synonymous_variant 1.0 isoniazid
kasA 2518456 c.342C>G synonymous_variant 1.0 isoniazid
kasA 2518459 c.345T>C synonymous_variant 1.0 isoniazid
kasA 2518462 c.348A>G synonymous_variant 1.0 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518475 c.361A>C synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518483 c.369C>G synonymous_variant 1.0 isoniazid
kasA 2518492 c.378C>T synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518571 p.Val153Thr missense_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>G synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>G synonymous_variant 1.0 isoniazid
kasA 2518594 c.480C>G synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>A synonymous_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518657 c.543G>A synonymous_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518697 p.Cys195Ala missense_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518717 c.603C>G synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>A synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518849 c.735G>C synonymous_variant 1.0 isoniazid
kasA 2518855 c.741C>G synonymous_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518877 p.Lys255Arg missense_variant 0.97 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518893 p.Lys260Arg missense_variant 1.0 isoniazid
kasA 2518898 c.784T>C synonymous_variant 1.0 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518907 c.793T>C synonymous_variant 1.0 isoniazid
kasA 2518912 c.798G>C synonymous_variant 1.0 isoniazid
kasA 2518921 c.807T>C synonymous_variant 1.0 isoniazid
kasA 2518939 c.825T>C synonymous_variant 1.0 isoniazid
kasA 2518942 c.828T>C synonymous_variant 1.0 isoniazid
kasA 2518960 c.846C>G synonymous_variant 1.0 isoniazid
kasA 2518966 c.852T>C synonymous_variant 1.0 isoniazid
kasA 2518967 c.853_855delGTTinsAG frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518978 c.864T>C synonymous_variant 1.0 isoniazid
kasA 2518990 c.876T>G synonymous_variant 1.0 isoniazid
kasA 2518993 c.879C>G synonymous_variant 1.0 isoniazid
kasA 2519008 c.894C>G synonymous_variant 1.0 isoniazid
kasA 2519011 c.897G>C synonymous_variant 1.0 isoniazid
kasA 2519012 c.898_900delTTGinsCA frameshift_variant&missense_variant 1.0 isoniazid
kasA 2519017 c.903G>C synonymous_variant 1.0 isoniazid
kasA 2519020 c.906G>C synonymous_variant 1.0 isoniazid
kasA 2519021 p.Ala303Lys missense_variant 1.0 isoniazid
kasA 2519026 c.912C>T synonymous_variant 1.0 isoniazid
kasA 2519027 p.Ile305Val missense_variant 1.0 isoniazid
kasA 2519062 c.948T>G synonymous_variant 1.0 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.94 isoniazid
kasA 2519077 c.963G>C synonymous_variant 1.0 isoniazid
kasA 2519092 c.978C>T synonymous_variant 1.0 isoniazid
kasA 2519095 c.981C>G synonymous_variant 1.0 isoniazid
kasA 2519107 c.993T>C synonymous_variant 1.0 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 1.0 isoniazid
kasA 2519112 p.Gln333Arg missense_variant 1.0 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 1.0 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 1.0 isoniazid
kasA 2519167 c.1053T>C synonymous_variant 1.0 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 1.0 isoniazid
kasA 2519176 c.1062G>A synonymous_variant 1.0 isoniazid
kasA 2519179 c.1065G>T synonymous_variant 1.0 isoniazid
kasA 2519182 c.1068G>C synonymous_variant 1.0 isoniazid
kasA 2519191 c.1077G>A synonymous_variant 1.0 isoniazid
kasA 2519192 c.1078C>T synonymous_variant 1.0 isoniazid
kasA 2519197 c.1083G>C synonymous_variant 1.0 isoniazid
kasA 2519200 c.1086G>T synonymous_variant 1.0 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 1.0 isoniazid
kasA 2519215 c.1101C>A synonymous_variant 1.0 isoniazid
kasA 2519221 c.1107G>C synonymous_variant 1.0 isoniazid
kasA 2519224 c.1110C>G synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 1.0 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 1.0 isoniazid
kasA 2519266 c.1152C>T synonymous_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 1.0 isoniazid
kasA 2519287 c.1173T>C synonymous_variant 1.0 isoniazid
kasA 2519295 p.Tyr394Phe missense_variant 1.0 isoniazid
kasA 2519299 c.1185C>T synonymous_variant 1.0 isoniazid
kasA 2519305 c.1191A>G synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
kasA 2519323 c.1209G>A synonymous_variant 1.0 isoniazid
kasA 2519338 c.1224T>C synonymous_variant 1.0 isoniazid
eis 2715649 c.-317C>G upstream_gene_variant 1.0 amikacin
kanamycin
eis 2715652 c.-320T>C upstream_gene_variant 1.0 amikacin
kanamycin
eis 2715663 c.-331C>G upstream_gene_variant 1.0 amikacin
kanamycin
eis 2715665 c.-333A>C upstream_gene_variant 1.0 amikacin
kanamycin
eis 2715673 c.-343_-341delCTTinsGC upstream_gene_variant 0.93 amikacin
kanamycin
eis 2715677 c.-346_-345delCAinsGG upstream_gene_variant 0.93 amikacin
kanamycin
eis 2715698 c.-366T>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715706 c.-374G>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715709 c.-377C>T upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715715 c.-383G>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715718 c.-386T>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715724 c.-392T>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715734 c.-402T>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715742 c.-410T>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715748 c.-416A>C upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715759 c.-427G>A upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715760 c.-430_-428delTCAinsCGC upstream_gene_variant 0.95 amikacin
kanamycin
eis 2715795 c.-463T>C upstream_gene_variant 0.8 amikacin
kanamycin
eis 2715799 c.-467A>G upstream_gene_variant 0.8 amikacin
kanamycin
eis 2715811 c.-481_-479delAGTinsGC upstream_gene_variant 0.8 amikacin
kanamycin
ahpC 2726233 p.Gln14Arg missense_variant 1.0 isoniazid
ahpC 2726237 c.45C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726243 c.51T>G synonymous_variant 1.0 isoniazid
ahpC 2726246 c.54C>G synonymous_variant 1.0 isoniazid
ahpC 2726252 c.60C>T synonymous_variant 1.0 isoniazid
ahpC 2726255 c.63T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726264 c.72C>G synonymous_variant 1.0 isoniazid
ahpC 2726282 c.90G>A synonymous_variant 1.0 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 1.0 isoniazid
ahpC 2726304 p.Ile38Leu missense_variant 1.0 isoniazid
ahpC 2726312 c.120T>C synonymous_variant 1.0 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 1.0 isoniazid
ahpC 2726322 p.Pro44Glu missense_variant 1.0 isoniazid
ahpC 2726336 c.144G>C synonymous_variant 1.0 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 1.0 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 1.0 isoniazid
ahpC 2726369 c.177C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726378 c.186T>C synonymous_variant 1.0 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 1.0 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 1.0 isoniazid
ahpC 2726432 c.240C>G synonymous_variant 1.0 isoniazid
ahpC 2726441 c.249G>C synonymous_variant 1.0 isoniazid
ahpC 2726444 c.252G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726447 c.255T>C synonymous_variant 1.0 isoniazid
ahpC 2726453 c.261T>C synonymous_variant 1.0 isoniazid
ahpC 2726467 p.Ala92Val missense_variant 1.0 isoniazid
ahpC 2726471 c.279T>C synonymous_variant 1.0 isoniazid
ahpC 2726477 c.285G>A synonymous_variant 1.0 isoniazid
ahpC 2726483 c.291T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726493 c.301_303delAACinsGG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
ahpC 2726504 c.312A>G synonymous_variant 1.0 isoniazid
ahpC 2726506 p.Thr105Lys missense_variant 1.0 isoniazid Uncertain significance
ahpC 2726508 c.316_318delTTAinsCG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
ahpC 2726513 c.321C>G synonymous_variant 1.0 isoniazid
ahpC 2726528 c.336C>G synonymous_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726621 c.429G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726627 c.435G>A synonymous_variant 1.0 isoniazid
ahpC 2726639 c.447C>G synonymous_variant 1.0 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726648 c.456T>A synonymous_variant 1.0 isoniazid
ahpC 2726651 c.459G>C synonymous_variant 1.0 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726660 c.468C>A synonymous_variant 1.0 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 1.0 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 1.0 isoniazid
ahpC 2726684 c.492G>C synonymous_variant 1.0 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 1.0 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 1.0 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
ahpC 2726699 c.507G>A synonymous_variant 1.0 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 1.0 isoniazid
folC 2746141 c.1458G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746158 c.1441T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746165 c.1434T>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746174 c.1425A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746183 c.1416T>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746264 c.1333_1335delTCAinsGG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2746270 c.1329C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746273 c.1326T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746282 c.1317T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746285 c.1314T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746307 p.Arg431Thr missense_variant 1.0 para-aminosalicylic_acid
folC 2746330 p.Glu423Asp missense_variant 1.0 para-aminosalicylic_acid
folC 2746333 c.1264_1266delGGCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2746336 c.1263C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746351 c.1248C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746360 c.1239T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746378 c.1221G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746390 c.1209G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746400 p.Ser400Val missense_variant 1.0 para-aminosalicylic_acid
folC 2746420 c.1179A>G synonymous_variant 0.95 para-aminosalicylic_acid
folC 2746426 c.1173G>C synonymous_variant 0.92 para-aminosalicylic_acid
folC 2746566 p.Ala345Thr missense_variant 1.0 para-aminosalicylic_acid
folC 2746584 c.1015T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746594 c.1005T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746609 c.990T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746612 c.987C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746617 p.Ala328Ser missense_variant 1.0 para-aminosalicylic_acid
folC 2746624 c.975C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746627 p.Asp324Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2746631 p.Gly323Val missense_variant 1.0 para-aminosalicylic_acid
folC 2746642 c.957T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746657 c.942T>C synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746675 c.922_924delTCCinsGG frameshift_variant&missense_variant 0.97 para-aminosalicylic_acid
folC 2746678 c.921T>G synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746684 c.915C>G synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746687 c.910_912delCTCinsGG frameshift_variant&missense_variant 0.97 para-aminosalicylic_acid
folC 2746691 p.Val303Ala missense_variant 0.97 para-aminosalicylic_acid
folC 2746714 c.885T>C synonymous_variant 0.98 para-aminosalicylic_acid
folC 2746728 c.871T>C synonymous_variant 0.98 para-aminosalicylic_acid
folC 2746734 p.Ile289Val missense_variant 0.97 para-aminosalicylic_acid
folC 2746744 c.855T>G synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746759 c.840G>A synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746765 c.834A>G synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746771 c.828A>C synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746777 c.822T>A synonymous_variant 0.97 para-aminosalicylic_acid
folC 2746785 p.Val272Ile missense_variant 0.97 para-aminosalicylic_acid
folC 2746791 p.Ile270Val missense_variant 0.96 para-aminosalicylic_acid
folC 2746793 p.Gln269Arg missense_variant 0.96 para-aminosalicylic_acid
folC 2746795 c.804A>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2746798 c.799_801delCGGinsGC frameshift_variant&synonymous_variant 0.96 para-aminosalicylic_acid
folC 2746801 c.796_798delCTAinsTG frameshift_variant&synonymous_variant 0.96 para-aminosalicylic_acid
folC 2746813 c.786A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746819 c.780T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746836 p.Ser255Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746837 c.762G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746857 p.Glu248Gln missense_variant 1.0 para-aminosalicylic_acid
folC 2746876 p.Val241Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746881 p.Lys240Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2746885 c.714C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746891 c.708T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746895 p.Gly235Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746903 c.696G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746920 p.Ser227Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746921 c.678T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746929 p.Pro224Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2746934 p.Arg222Lys missense_variant 1.0 para-aminosalicylic_acid
folC 2746936 p.Thr221Asn missense_variant 1.0 para-aminosalicylic_acid
folC 2746948 c.651G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746957 c.642G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746975 c.624T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746979 p.Ala207Asp missense_variant 1.0 para-aminosalicylic_acid
folC 2746981 c.618T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2746990 p.Asp203Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2746999 c.600T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747007 p.Ser198Gly missense_variant 1.0 para-aminosalicylic_acid
folC 2747011 c.588G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747023 c.576C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747036 p.Asn188Ser missense_variant 1.0 para-aminosalicylic_acid
folC 2747059 c.540T>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747070 p.Met177Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747074 c.525G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747116 c.483G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747230 c.369C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747239 c.360T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747260 c.337_339delAAGinsCC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747263 c.336C>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747274 p.Ser109Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747278 c.321C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747284 c.315G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747289 p.Pro104Ala missense_variant 1.0 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747341 c.258C>G synonymous_variant 0.98 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 0.98 para-aminosalicylic_acid
folC 2747365 c.234G>C synonymous_variant 0.98 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 0.98 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 0.98 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 0.97 para-aminosalicylic_acid
folC 2747412 p.Ser63Gly missense_variant 0.97 para-aminosalicylic_acid
folC 2747414 p.Arg62Leu missense_variant 0.97 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 0.97 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 0.97 para-aminosalicylic_acid
folC 2747443 c.156G>C synonymous_variant 0.97 para-aminosalicylic_acid
folC 2747467 p.Asp44Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2747473 p.Arg42Lys missense_variant 1.0 para-aminosalicylic_acid
folC 2747482 c.117G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747494 c.105C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747497 c.102C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747500 c.99A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747503 c.96T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747506 c.93G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747509 c.90T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747521 c.78C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747778 c.-180T>C upstream_gene_variant 0.87 para-aminosalicylic_acid
folC 2747790 c.-192G>C upstream_gene_variant 0.92 para-aminosalicylic_acid
folC 2747798 c.-200A>C upstream_gene_variant 0.92 para-aminosalicylic_acid
Rv2477c 2782393 c.1650C>A synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782399 c.1644T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782405 c.1638A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782408 c.1635T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782414 p.Asp543Glu missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782420 c.1623T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782432 c.1611G>T synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782444 c.1599G>A synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782475 p.Phe523Tyr missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782481 p.Lys521Arg missense_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.98 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782504 c.1539G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782531 c.1512C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782555 c.1488G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 p.Ile495Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782576 c.1467C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782587 p.Leu486Met missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782594 c.1449T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782597 c.1446G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782606 c.1437T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782612 c.1431T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782615 c.1428G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782651 c.1392T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782656 c.1387C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782675 c.1368G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782680 c.1363T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782684 c.1359T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782702 c.1341G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782705 c.1338G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782714 c.1329A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782720 c.1323T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782741 c.1302G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782744 c.1299A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782750 c.1293T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782759 c.1284A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782768 c.1275C>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin
amikacin Not assoc w R - Interim
Rv2477c 2782777 c.1266A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782816 c.1227T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782837 c.1206C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782849 c.1194G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782867 p.Ala392Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782879 c.1164C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782882 c.1161T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782913 p.Ser377Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783017 c.1026C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783080 c.963G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783085 p.Val320Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783087 p.Asn319Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783101 c.942G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783105 p.Val313Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783107 c.936G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783110 c.933C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783128 c.915C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783134 c.909G>A synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783167 c.876G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783179 c.864G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783182 c.861C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783200 c.843G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783214 p.Ala277Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783215 c.828G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783286 p.Ala253Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783287 c.756C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783308 c.735G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783323 c.720C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783338 c.705C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783347 c.696C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783407 c.636C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.618C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783432 p.Ser204Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783510 p.Pro178His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783526 c.517C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783569 c.474C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 p.Glu128Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 c.244_246delGACinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 p.Asp61Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784051 c.-9C>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784299 c.-257A>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784300 c.-258G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784311 c.-269T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784312 c.-270T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784315 c.-273G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784318 c.-276G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784321 c.-279A>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784324 c.-282G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784327 c.-285G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784354 c.-312T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784357 c.-316_-315delTTinsAC upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784366 c.-324G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784375 c.-333T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784378 c.-336A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784381 c.-339T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784390 c.-348G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784396 c.-354A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784405 c.-363T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784414 c.-372A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784426 c.-386_-384delTTGinsCA upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784441 c.-399G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784456 c.-414A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784465 c.-423T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784501 c.-459T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784510 c.-470_-468delAGCinsGCG upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784516 c.-474C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784519 c.-477G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784528 c.-486T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784558 c.-516A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859306 c.1113T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859318 c.1101A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859335 c.1084T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859468 c.951G>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859471 c.948A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859486 c.933A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859489 p.Val310Ala missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859492 c.927G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859498 c.921C>A synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859510 c.909T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859513 c.906A>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859525 c.894T>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859528 c.891T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859534 c.885A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859539 c.880C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859540 c.879A>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859546 c.873T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859552 p.His289Gln missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859574 p.Ala282Val missense_variant 0.91 clofazimine
bedaquiline
pepQ 2859584 p.Gln279Lys missense_variant 0.95 clofazimine
bedaquiline
pepQ 2859591 c.828A>G synonymous_variant 0.88 clofazimine
bedaquiline
pepQ 2859594 c.825T>C synonymous_variant 0.88 clofazimine
bedaquiline
pepQ 2859600 c.819G>C synonymous_variant 0.87 clofazimine
bedaquiline
pepQ 2859603 p.Gly272Asp missense_variant 0.86 clofazimine
bedaquiline
pepQ 2859606 c.813G>C synonymous_variant 0.86 clofazimine
bedaquiline
pepQ 2859612 p.Glu269Ala missense_variant 0.86 clofazimine
bedaquiline
pepQ 2859618 c.801T>C synonymous_variant 0.87 clofazimine
bedaquiline
pepQ 2859623 p.Pro266Ala missense_variant 0.87 clofazimine
bedaquiline
pepQ 2859625 p.Leu265Arg missense_variant 0.88 clofazimine
bedaquiline
pepQ 2859635 p.Gln262Glu missense_variant 0.89 clofazimine
bedaquiline
pepQ 2859639 c.780T>C synonymous_variant 0.9 clofazimine
bedaquiline
pepQ 2859646 p.Gln258Arg missense_variant 0.91 clofazimine
bedaquiline
pepQ 2859648 c.771A>G synonymous_variant 0.91 clofazimine
bedaquiline
pepQ 2859660 c.759G>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859667 p.Gln251Arg missense_variant 0.94 clofazimine
bedaquiline
pepQ 2859678 c.741A>G synonymous_variant 0.95 clofazimine
bedaquiline
pepQ 2859691 c.727_728insGTAAGGCCG conservative_inframe_insertion 0.89 clofazimine
bedaquiline
pepQ 2859704 c.715T>C synonymous_variant 0.94 clofazimine
bedaquiline
pepQ 2859723 c.696T>C synonymous_variant 0.97 clofazimine Not assoc w R - Interim
bedaquiline
pepQ 2859732 c.687C>T synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859735 c.684G>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859747 c.672C>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859765 c.654G>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859778 p.Val214Ala missense_variant 0.98 clofazimine
bedaquiline
pepQ 2859781 p.Gln213Ala missense_variant 0.98 clofazimine
bedaquiline
pepQ 2859793 p.Asp209Gly missense_variant 0.97 clofazimine
bedaquiline
pepQ 2859801 c.618G>C synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859834 c.585T>C synonymous_variant 0.97 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859852 c.567A>G synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859855 c.564G>C synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859864 c.555T>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859870 c.549T>C synonymous_variant 0.97 clofazimine
bedaquiline
pepQ 2859873 c.546T>C synonymous_variant 0.96 clofazimine
bedaquiline
pepQ 2859908 p.Gln171Glu missense_variant 0.98 clofazimine
bedaquiline
pepQ 2859909 c.510G>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859918 c.501A>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859921 c.498C>G synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859924 c.495G>C synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859942 c.477C>G synonymous_variant 0.98 clofazimine
bedaquiline
pepQ 2859950 c.469T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859951 c.468C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859966 c.453T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859972 c.447A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859975 c.444A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859984 c.435A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859987 c.432A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860001 p.Leu140Val missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860014 c.405A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860017 c.402T>C synonymous_variant 1.0 clofazimine
bedaquiline Not assoc w R - Interim
pepQ 2860326 c.93A>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860335 c.84A>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860344 p.Ser25Thr missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860349 p.Ile24Val missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860359 c.60T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860364 c.55T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860369 c.49_50delTCinsAG synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860375 p.Ala15Gly missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860377 p.Ile14Met missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860383 c.36A>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2860392 p.Lys9Asn missense_variant 1.0 clofazimine
bedaquiline
pepQ 2860446 c.-28T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860447 c.-29A>G upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860448 c.-30C>T upstream_gene_variant 1.0 clofazimine
bedaquiline
pepQ 2860456 c.-39_-38delAGinsCC upstream_gene_variant 1.0 clofazimine
bedaquiline
ribD 2986649 c.-190G>C upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986655 c.-184_-183delAAinsCG upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986661 c.-178G>A upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986664 c.-175A>C upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986667 c.-172T>G upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986679 c.-160G>A upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986688 c.-151C>G upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986700 c.-139C>A upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986703 c.-136A>C upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986711 c.-128G>T upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986731 c.-108A>T upstream_gene_variant 1.0 para-aminosalicylic_acid
ribD 2986736 c.-103A>C upstream_gene_variant 1.0 para-aminosalicylic_acid
Rv2680 2995777 c.-328A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2995779 c.-326G>A upstream_gene_variant 1.0 capreomycin
Rv2680 2995786 c.-319C>G upstream_gene_variant 1.0 capreomycin
Rv2680 2995789 c.-316T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2995790 c.-315C>T upstream_gene_variant 1.0 capreomycin
Rv2680 2995798 c.-307T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2995810 c.-295T>G upstream_gene_variant 1.0 capreomycin
Rv2680 2995831 c.-274C>T upstream_gene_variant 1.0 capreomycin
Rv2680 2995834 c.-271G>C upstream_gene_variant 1.0 capreomycin
Rv2680 2995840 c.-265G>A upstream_gene_variant 1.0 capreomycin
Rv2680 2995844 c.-261A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2995847 c.-258_-256delGGGinsAT upstream_gene_variant 1.0 capreomycin
Rv2680 2995855 c.-250T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2995858 c.-247T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2995870 c.-235G>C upstream_gene_variant 1.0 capreomycin
Rv2680 2995879 c.-226G>C upstream_gene_variant 1.0 capreomycin
Rv2680 2995888 c.-217C>T upstream_gene_variant 1.0 capreomycin
Rv2680 2995894 c.-211A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2995897 c.-208G>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996563 c.-176A>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996587 c.483G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996593 c.-146T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996608 c.-131A>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996614 c.-125G>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996617 c.-122A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996638 p.Asp178Glu missense_variant 1.0 capreomycin
Rv2680 2996639 c.535_537delCTGinsGC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2996644 c.-95C>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996646 p.Ala181Val missense_variant 1.0 capreomycin
Rv2681 2996650 c.-89T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996654 p.Gln184Lys missense_variant 1.0 capreomycin
Rv2681 2996671 c.-68C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996674 c.-65G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996677 c.-62G>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996683 c.-56G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996686 c.-53C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996692 c.-47G>A upstream_gene_variant 1.0 capreomycin
Rv2681 2996698 c.-41A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996699 p.Ala199Thr missense_variant 1.0 capreomycin
Rv2681 2996906 c.168A>G synonymous_variant 1.0 capreomycin
Rv2681 2996918 c.180G>A synonymous_variant 1.0 capreomycin
Rv2681 2996921 c.183G>C synonymous_variant 1.0 capreomycin
Rv2681 2996940 p.Gly68Asn missense_variant 1.0 capreomycin
Rv2681 2996945 c.207C>G synonymous_variant 1.0 capreomycin
Rv2681 2996969 c.231G>C synonymous_variant 1.0 capreomycin
Rv2681 2996974 p.Glu79Gly missense_variant 1.0 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 1.0 capreomycin
Rv2681 2996990 c.252G>C synonymous_variant 1.0 capreomycin
Rv2681 2997013 p.Gly92Ala missense_variant 1.0 capreomycin
Rv2681 2997021 c.283T>C synonymous_variant 1.0 capreomycin
Rv2681 2997028 p.Val97Ala missense_variant 1.0 capreomycin
Rv2681 2997033 p.Ala99Arg missense_variant 1.0 capreomycin
Rv2681 2997038 c.300G>C synonymous_variant 1.0 capreomycin
Rv2681 2997053 c.315C>G synonymous_variant 1.0 capreomycin
Rv2681 2997054 p.Ser106Gly missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997060 p.Asn108Asp missense_variant 1.0 capreomycin
Rv2681 2997065 c.327G>A synonymous_variant 1.0 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 1.0 capreomycin
Rv2681 2997101 c.363T>C synonymous_variant 1.0 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 1.0 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 1.0 capreomycin
Rv2681 2997122 c.384A>G synonymous_variant 0.96 capreomycin Not assoc w R - Interim
Rv2681 2997125 c.387G>A synonymous_variant 0.96 capreomycin
Rv2681 2997128 c.390A>G synonymous_variant 0.96 capreomycin
Rv2681 2997134 c.396A>G synonymous_variant 0.95 capreomycin
Rv2681 2997149 c.411T>C synonymous_variant 0.95 capreomycin
Rv2681 2997155 c.417G>A synonymous_variant 0.94 capreomycin
Rv2681 2997158 c.420C>G synonymous_variant 0.94 capreomycin
Rv2681 2997173 c.435T>C synonymous_variant 0.93 capreomycin
Rv2681 2997176 c.438A>G synonymous_variant 0.93 capreomycin
Rv2681 2997189 p.Ala151Thr missense_variant 1.0 capreomycin
Rv2752c 3064551 c.1641C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064566 c.1626G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064584 c.1608G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064596 c.1596G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064599 c.1593A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064602 c.1590T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064628 p.Asn522Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064635 p.Val519Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064640 c.1552T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064642 p.Ser517Gln missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064644 c.1548A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064653 c.1539A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064659 c.1533G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064664 p.Lys510Glu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064677 c.1515A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064695 c.1497A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064776 c.1416T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064779 c.1413C>T synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064790 c.1402T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064791 c.1401T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064800 c.1392G>A synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064815 c.1377T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064824 c.1368C>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064832 p.Ala454Thr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064838 c.1354T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064857 c.1335C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064860 c.1332G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064872 c.1320T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064877 p.Ser439Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064887 c.1305A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064896 c.1296T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064932 c.1260T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064947 c.1245A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064950 c.1242C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064955 p.Thr413Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064958 p.Ser412Arg missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064959 c.1233C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064962 c.1230C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065004 c.1188G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065288 c.904T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065292 c.900T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065295 p.Gln299Arg missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065298 p.Asp298Glu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065311 p.Thr294Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065313 c.879A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065324 p.Ala290Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065334 c.858C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065337 c.855T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065346 p.Ala282Asp missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065352 c.840A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065355 c.837A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065367 c.823_825delCAAinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065372 c.820A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065373 c.819A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065378 p.Val272Ile missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065381 p.Arg271Gly missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065400 c.792A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065403 c.789C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065418 c.774A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065436 c.756A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065442 c.750T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065449 p.Ile248Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065457 c.735A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065481 c.711T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065484 c.708G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065496 c.696G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065517 c.675C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065531 p.Thr221Ala missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065532 c.660A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065541 c.651A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065553 c.639A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065562 c.630T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065875 p.Lys106Thr missense_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065880 c.312C>T synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065901 c.291A>G synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065908 p.Lys95Arg missense_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065916 c.276T>C synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065947 p.Gly82Ala missense_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsCA frameshift_variant&missense_variant 0.96 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065963 c.229C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065979 c.213T>C synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065988 c.204A>G synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.96 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066015 c.177G>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>C synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066039 p.Gly51Thr missense_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066260 c.-69T>C upstream_gene_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066264 c.-73C>T upstream_gene_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066276 c.-85G>C upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066279 c.-88A>G upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066285 c.-96_-94delGCCinsCG upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066290 c.-99G>A upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066294 c.-103C>G upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066299 c.-108C>T upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066306 c.-115T>C upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066313 c.-122T>C upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066320 c.-129A>G upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066321 c.-130C>T upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066426 c.-235T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066429 c.-238G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-268T>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-274G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066468 c.-277C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066477 c.-286C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066480 c.-291_-289delGCCinsTT upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066486 c.-295G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066513 c.-322C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>T upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>A upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066601 c.-410C>G upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>C upstream_gene_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066630 c.-439G>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066637 c.-447_-446delTCinsAA upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066639 c.-448G>C upstream_gene_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066658 c.-467A>G upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066662 c.-471C>A upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066663 c.-472G>A upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066675 c.-485_-484delCGinsTC upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066681 c.-490G>T upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066687 c.-496G>C upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066696 c.-505T>C upstream_gene_variant 0.96 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066707 c.-516A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066715 c.-524A>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066744 c.-553C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066747 c.-558_-556delCAAinsATC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066756 c.-567_-565delCGGinsACC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-630_-628delTGTinsGCC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-631T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066846 c.-655G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066855 c.-664T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066891 c.-700G>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066900 c.-709A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066925 c.-735_-734delATinsCG upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066933 c.-743_-742delGGinsAC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066966 c.-775C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067199 c.747A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067205 c.741G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067220 c.726G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067223 c.723G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067244 p.Thr234Arg missense_variant 1.0 para-aminosalicylic_acid
thyX 3067249 p.Thr233Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067250 c.694_696delGTGinsAC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067253 c.693G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067277 c.669C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067282 p.Val222Met missense_variant 1.0 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 1.0 para-aminosalicylic_acid
thyX 3067304 c.642A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067442 c.504C>T synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067515 p.Ser144Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067535 c.411C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067541 c.405C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067550 c.396G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 1.0 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 1.0 para-aminosalicylic_acid
thyX 3067577 p.Glu123Asp missense_variant 1.0 para-aminosalicylic_acid
thyX 3067586 c.360C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067610 p.Lys112Asn missense_variant 1.0 para-aminosalicylic_acid
thyX 3067613 c.333G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067616 c.330C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067619 c.327A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067634 c.310_312delCTCinsTG frameshift_variant&synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067658 c.288C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067673 c.273C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.98 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.98 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.97 para-aminosalicylic_acid
thyX 3067915 c.31C>T synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067925 c.21G>A synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067939 p.Glu3Gln missense_variant 0.9 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3073874 p.Ile200Val missense_variant 0.94 para-aminosalicylic_acid
thyA 3073887 p.Ser195Gly missense_variant 0.94 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073893 c.579C>A synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073908 p.Met188Ile missense_variant 0.96 para-aminosalicylic_acid
thyA 3073923 c.547_549delTTGinsCA frameshift_variant&missense_variant 0.97 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073950 c.522G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074028 c.444G>A synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 0.95 para-aminosalicylic_acid
thyA 3074061 p.Glu137Asp missense_variant 0.95 para-aminosalicylic_acid
thyA 3074076 c.396C>A synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074120 c.352T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074121 p.Asp117Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3074211 c.261A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074217 c.255T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074244 c.228A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074250 c.222G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074262 p.Gly70Ala missense_variant 1.0 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 1.0 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074285 c.187T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074286 c.186T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074305 p.Ala56Val missense_variant 1.0 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074322 c.150C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074325 c.147A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074349 c.123T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074364 c.108T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074397 c.75A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074415 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074418 c.54A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074423 p.Pro17Ala missense_variant 1.0 para-aminosalicylic_acid
thyA 3074426 p.Thr16Ala missense_variant 1.0 para-aminosalicylic_acid
thyA 3074433 c.39A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074442 c.28_30delTTCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3074463 c.9A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074470 p.Val1Ala missense_variant 1.0 para-aminosalicylic_acid
thyA 3074475 c.-4A>G upstream_gene_variant 0.96 para-aminosalicylic_acid
thyA 3074477 c.-6T>C upstream_gene_variant 0.96 para-aminosalicylic_acid
thyA 3074485 c.-14A>G upstream_gene_variant 0.96 para-aminosalicylic_acid
thyA 3074490 c.-19G>A upstream_gene_variant 0.96 para-aminosalicylic_acid
thyA 3074520 c.-49delGinsCC upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074524 c.-53T>G upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074528 c.-57T>C upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074529 c.-58G>C upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074539 c.-70_-69delGT upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074545 c.-74G>A upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074547 c.-76G>A upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074552 c.-81C>A upstream_gene_variant 1.0 para-aminosalicylic_acid
thyA 3074565 c.-94C>T upstream_gene_variant 1.0 para-aminosalicylic_acid
ald 3087224 c.405A>G synonymous_variant 1.0 cycloserine
ald 3087233 c.414T>C synonymous_variant 1.0 cycloserine
ald 3087236 c.417A>G synonymous_variant 1.0 cycloserine
ald 3087240 p.Ala141Ser missense_variant 1.0 cycloserine
ald 3087251 c.432T>C synonymous_variant 1.0 cycloserine
ald 3087254 c.435C>G synonymous_variant 1.0 cycloserine
ald 3087257 c.438T>C synonymous_variant 1.0 cycloserine
ald 3087260 c.441C>T synonymous_variant 1.0 cycloserine
ald 3087272 c.453A>G synonymous_variant 1.0 cycloserine
ald 3087281 c.462G>C synonymous_variant 1.0 cycloserine
ald 3087284 c.465C>G synonymous_variant 1.0 cycloserine
ald 3087290 c.471T>C synonymous_variant 1.0 cycloserine
ald 3087311 c.492C>G synonymous_variant 1.0 cycloserine
ald 3087318 c.499_501delGAAinsAG frameshift_variant&missense_variant 1.0 cycloserine
ald 3087321 c.502_504delCCGinsGC frameshift_variant&missense_variant 1.0 cycloserine
ald 3087368 c.549A>C synonymous_variant 1.0 cycloserine
ald 3087375 p.Ile186Val missense_variant 1.0 cycloserine
ald 3087381 p.Asn188Gly missense_variant 1.0 cycloserine
ald 3087392 c.573C>G synonymous_variant 1.0 cycloserine
ald 3087396 p.Thr193Ser missense_variant 1.0 cycloserine
ald 3087401 c.582T>C synonymous_variant 1.0 cycloserine
ald 3087403 p.Thr195Met missense_variant 1.0 cycloserine
ald 3087407 c.588T>G synonymous_variant 1.0 cycloserine
ald 3087410 c.591A>C synonymous_variant 1.0 cycloserine
ald 3087414 p.Ile199Val missense_variant 1.0 cycloserine
ald 3087423 p.Asp202Asn missense_variant 1.0 cycloserine
ald 3087596 c.777A>G synonymous_variant 1.0 cycloserine
ald 3087599 c.780A>G synonymous_variant 1.0 cycloserine
ald 3087602 c.783T>C synonymous_variant 1.0 cycloserine
ald 3087608 c.789A>G synonymous_variant 1.0 cycloserine
ald 3087617 c.798T>C synonymous_variant 1.0 cycloserine
ald 3087620 c.801A>C synonymous_variant 1.0 cycloserine
ald 3087621 p.Ala268Ser missense_variant 1.0 cycloserine
ald 3087641 c.822T>C synonymous_variant 1.0 cycloserine
ald 3087647 c.828A>G synonymous_variant 1.0 cycloserine
ald 3087649 p.Gly277Asp missense_variant 1.0 cycloserine
ald 3087653 c.834A>C synonymous_variant 1.0 cycloserine
ald 3087656 c.837A>G synonymous_variant 1.0 cycloserine
ald 3087659 c.840G>C synonymous_variant 1.0 cycloserine
ald 3087666 p.Tyr283His missense_variant 1.0 cycloserine
ald 3087671 c.852C>T synonymous_variant 1.0 cycloserine
ald 3087698 c.879G>C synonymous_variant 1.0 cycloserine
ald 3087704 c.885T>C synonymous_variant 1.0 cycloserine
ald 3087726 p.Ala303Ser missense_variant 1.0 cycloserine
ald 3087729 p.Ser304Ala missense_variant 1.0 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 1.0 cycloserine
ald 3087779 c.960T>C synonymous_variant 1.0 cycloserine
ald 3087786 c.967_969delGAGinsAA frameshift_variant&missense_variant 1.0 cycloserine
ald 3087791 c.972T>C synonymous_variant 1.0 cycloserine
ald 3087800 c.981T>C synonymous_variant 1.0 cycloserine
ald 3087809 c.990G>A synonymous_variant 1.0 cycloserine
ald 3087815 c.996G>A synonymous_variant 1.0 cycloserine
ald 3087825 p.Asn336Asp missense_variant 1.0 cycloserine
ald 3087830 c.1011G>C synonymous_variant 1.0 cycloserine
ald 3087833 c.1014A>T synonymous_variant 1.0 cycloserine
ald 3087836 c.1017A>G synonymous_variant 1.0 cycloserine
ald 3087840 c.1021_1023delAAAinsCT frameshift_variant&missense_variant 1.0 cycloserine
ald 3087845 c.1026T>G synonymous_variant 1.0 cycloserine
ald 3087860 p.Glu347Asp missense_variant 1.0 cycloserine
ald 3087867 c.1048_1050delTTAinsCG frameshift_variant&missense_variant 1.0 cycloserine
fbiD 3339171 c.54C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339180 c.63G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339186 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339190 c.73A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339215 p.Gln33Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339219 c.102T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339222 c.105C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339227 p.Asn37Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339246 c.129C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339255 c.138G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339256 c.139T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339273 c.156T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339279 c.162T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339282 c.165A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339286 p.Arg57Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339297 c.180T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiD 3339300 c.183T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiD 3339306 c.189C>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
whiB7 3569230 c.-551T>C upstream_gene_variant 1.0 streptomycin
amikacin
kanamycin
whiB7 3569235 c.-556C>G upstream_gene_variant 1.0 streptomycin
amikacin
kanamycin
whiB7 3569250 c.-571T>C upstream_gene_variant 1.0 streptomycin
amikacin
kanamycin
whiB7 3569259 c.-580C>G upstream_gene_variant 1.0 streptomycin
amikacin
kanamycin
whiB7 3569265 c.-586C>G upstream_gene_variant 1.0 streptomycin
amikacin
kanamycin
whiB7 3569276 c.-597G>C upstream_gene_variant 1.0 streptomycin
amikacin
kanamycin
Rv3236c 3612649 c.468G>T synonymous_variant 0.9 pyrazinamide
Rv3236c 3612667 c.450T>C synonymous_variant 0.94 pyrazinamide
Rv3236c 3612676 c.441A>G synonymous_variant 0.95 pyrazinamide
Rv3236c 3612685 c.432C>T synonymous_variant 1.0 pyrazinamide
Rv3236c 3612694 c.421_423delCGTinsGC frameshift_variant&synonymous_variant 1.0 pyrazinamide Uncertain significance
Rv3236c 3612708 c.409T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612712 c.405G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612721 c.396G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612730 c.387C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
Rv3236c 3612736 c.381T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612757 p.Gly120Ala missense_variant 1.0 pyrazinamide
Rv3236c 3612760 c.357C>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612769 c.348T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612772 c.345T>A synonymous_variant 1.0 pyrazinamide
Rv3236c 3612786 c.331T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612787 c.330T>G synonymous_variant 1.0 pyrazinamide
Rv3236c 3612796 c.321G>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612805 c.312T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612811 c.306G>A synonymous_variant 1.0 pyrazinamide
Rv3236c 3612829 c.288T>C synonymous_variant 1.0 pyrazinamide
Rv3236c 3612838 c.279G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
Rv3236c 3612841 c.276G>C synonymous_variant 1.0 pyrazinamide
lpqB 3622206 c.1590_*952del frameshift_variant&stop_lost&splice_region_variant 0.92 bedaquiline
rifampicin Uncertain significance
lpqB 3623360 c.1551A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623363 c.1548T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623366 c.1545T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623372 c.1539G>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R
lpqB 3623379 p.Ala511Gly missense_variant 0.97 bedaquiline
rifampicin
lpqB 3623388 p.Thr508Ile missense_variant 0.98 bedaquiline
rifampicin
lpqB 3623393 c.1518A>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623432 c.1479G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623442 p.Ser490Asn missense_variant 0.98 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623450 c.1461G>C synonymous_variant 0.98 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623480 c.1431C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623484 p.Phe476Tyr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623492 c.1419T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623512 p.Gly467Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623532 p.Gly460Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623561 c.1350T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623573 c.1338T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623576 c.1335T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623580 p.Asn444Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623587 p.Ala442Pro missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623591 c.1320G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623598 p.Arg438Thr missense_variant 0.97 bedaquiline
rifampicin
lpqB 3623602 p.Ser437Gly missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623614 p.Thr433Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623615 c.1296G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623627 c.1284T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623633 c.1278G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623645 c.1266G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623648 c.1263A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623660 c.1251A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623666 c.1245A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623676 p.Val412Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623682 p.Thr410Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623684 c.1227T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623723 c.1188C>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3623731 p.Ser394Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623736 p.Ser392Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623739 p.His391Arg missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3623756 c.1155G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623782 p.Val377Ile missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623789 c.1122T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623799 p.Glu371Met missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623807 c.1104T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623810 c.1101G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623816 c.1093_1095delGGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3623970 p.Ala314Gly missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623972 c.939C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623975 c.936T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623987 c.924G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623990 c.921G>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624002 c.909G>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624014 c.897T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624026 c.885G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624032 c.879T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624041 p.Glu290Asp missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624050 c.861C>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624077 c.834G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624089 c.822C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624094 c.817A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624100 c.811T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624101 c.810C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624125 c.786A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624155 c.756G>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624158 c.753G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624173 c.738A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624176 c.735G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624194 c.717C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624200 c.711A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624204 p.Ser236Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624209 c.702A>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624212 c.699C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624224 c.687T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624242 c.669A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624245 c.666A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624254 c.657T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624257 c.654C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624266 c.645T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624269 c.642G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624274 p.Thr213Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624276 p.Arg212His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624283 p.Met210Leu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624287 c.624G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624290 c.621C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624293 c.618A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624296 c.615T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624299 c.612G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624308 c.603A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624320 c.591G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624407 c.504C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624416 c.495G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624452 c.459T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624455 c.456G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624464 c.447A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624476 c.435C>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624482 c.429T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624485 p.Asp142Gly missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3624518 c.393T>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624527 p.Gln128Val missense_variant 0.95 bedaquiline
rifampicin
lpqB 3624530 c.381T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624542 c.369G>A synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624545 c.366T>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624551 c.360G>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624557 c.354T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624560 c.351G>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624563 c.348C>G synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624572 c.339C>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624575 c.336T>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624594 p.Val106Ala missense_variant 0.96 bedaquiline
rifampicin
lpqB 3624603 p.Lys103Arg missense_variant 0.95 bedaquiline
rifampicin
lpqB 3624605 c.306G>A synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624612 p.Ser100Ala missense_variant 0.95 bedaquiline
rifampicin
lpqB 3624614 c.297A>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624623 c.288C>G synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624629 c.282G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624707 c.204G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624722 c.189C>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624749 c.162G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624755 c.154_156delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624770 c.141T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624776 c.135T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624783 p.Ser43Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624788 c.123A>G synonymous_variant 0.97 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624807 p.Val35Ala missense_variant 0.97 bedaquiline
rifampicin
lpqB 3624812 c.99T>G synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624815 c.96A>G synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624824 c.87A>C synonymous_variant 0.93 bedaquiline
rifampicin
lpqB 3624847 p.Thr22Ser missense_variant 0.85 bedaquiline
rifampicin
lpqB 3625060 c.-150G>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 0.91 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625066 c.-156G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625080 c.-170C>A upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625090 c.-180C>A upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Gln missense_variant 0.93 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625117 c.-207T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 0.98 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625141 c.-231T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.98 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 0.98 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625258 c.-348G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625294 c.-384C>T upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625298 p.Ala439Val missense_variant 0.98 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.98 bedaquiline
rifampicin
lpqB 3625327 c.-417A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625357 c.-447T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625366 c.-456C>A upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625372 c.-462A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625375 c.-465A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625387 c.-477T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625396 c.-486G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3625407 p.Gln403Glu missense_variant 0.92 bedaquiline
rifampicin
mtrB 3625408 c.1204_1206delGAGinsCC frameshift_variant&missense_variant 0.92 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625411 p.Ala401Glu missense_variant 0.92 bedaquiline
rifampicin
mtrB 3625419 p.Leu399Met missense_variant 0.92 bedaquiline
rifampicin
lpqB 3625420 c.-510T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625426 c.-516G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625431 c.-521T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625438 c.-528T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625465 c.-555T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625471 c.-561C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625478 p.Asn379Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625480 c.1132_1134delAACinsCG frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625483 c.-573C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625486 c.-576G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625489 c.-579A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625497 c.1117T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625501 c.-591C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625510 c.-600T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625513 c.-603G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625528 c.-618G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625717 c.-807C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
mtrB 3625762 c.852A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625891 c.-981G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625912 c.702G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625915 c.699G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625920 c.694C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625942 c.672C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625945 c.669A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625951 c.663A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625955 p.Leu220Ala missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625967 p.Ala216Ile missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625978 c.636T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625988 p.Thr209Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625999 c.615A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626009 p.Ala202Lys missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626017 c.597T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626029 c.585A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626035 c.579G>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626048 p.Arg189Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626054 p.Leu187Ser missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626062 c.552T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626065 c.549G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626070 p.Ile182Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626077 c.537C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626086 c.528C>G synonymous_variant 0.96 bedaquiline
rifampicin
mtrB 3626092 c.522T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626095 p.Glu173Asp missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626101 p.Gln171His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626125 c.489C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626131 c.483G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626293 c.321G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626296 c.318T>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626308 c.306T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626317 c.297A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626320 c.294C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626332 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626349 p.Ser89Gly missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626353 c.261C>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626362 c.252A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626377 p.Asp79Glu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626383 c.231G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626386 c.228G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626390 p.Arg75Lys missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626404 c.210C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626410 c.204T>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626437 c.177T>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626443 c.171T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626449 c.165G>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626455 c.159C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626458 c.156C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626463 c.151C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626470 c.144A>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626491 c.123G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626500 c.114G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626735 c.-122C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626879 c.-266G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626882 c.468G>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3626888 c.460_462delTTGinsCA frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626891 c.-278G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626915 c.-302C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626924 c.-311G>A upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 0.98 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627170 c.-557C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627173 c.-560G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627197 c.-584T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627218 c.-605G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627227 c.123T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627296 c.-683T>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.96 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627377 c.-764G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrA 3627782 c.-433T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627794 c.-445G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627802 c.-453T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627804 c.-455G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627809 c.-462_-460delTGTinsCAG upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627812 c.-463G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627817 c.-468G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627820 c.-471C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627825 c.-477_-476delACinsGA upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627829 c.-480C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627839 c.-490T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627857 c.-508G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627863 c.-514G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627872 c.-523T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627876 c.-527T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627884 c.-535A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627893 c.-544T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
fbiB 3640833 c.-702G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640839 c.-696C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640850 p.Glu103Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640854 c.-681C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640857 c.-678G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640866 c.-669T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640901 p.Gln120Arg missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiB 3640911 c.-624C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640914 c.-621C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640917 c.-618G>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640920 c.-615A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640930 p.Glu130Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640935 c.-600C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640938 c.-597A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640944 c.-591T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640962 c.-573C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640965 c.-570C>G upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3640966 c.-569T>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3640974 c.432T>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiA 3640979 p.Thr146Ser missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3640983 c.-552C>T upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3640989 c.-546T>C upstream_gene_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3640995 c.-540A>G upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3640998 c.-537C>A upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3641001 c.-534T>C upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3641004 c.-531A>G upstream_gene_variant 0.94 clofazimine
pretomanid
delamanid
fbiB 3641016 c.-519C>T upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiA 3641021 p.Val160Ala missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3641049 c.-486T>C upstream_gene_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641073 c.-462T>G upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641097 c.-438T>C upstream_gene_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641100 c.-435T>A upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641103 c.-432T>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641112 c.-423T>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641118 p.Lys192Asn missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641119 p.Ser193Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641127 c.-408T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641128 p.Ala196Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3641164 p.Ile208Val missense_variant 0.97 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiA 3641170 p.Met210Leu missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641184 c.-351T>C upstream_gene_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641187 c.-348T>C upstream_gene_variant 0.98 clofazimine
pretomanid
delamanid
fbiA 3641200 p.Ile220Val missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiB 3641220 c.-315C>G upstream_gene_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641226 c.-309G>C upstream_gene_variant 0.97 clofazimine
pretomanid
delamanid
fbiA 3641234 p.Ala231Gly missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641244 c.-291G>T upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641246 p.Glu235Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3641256 c.-279A>C upstream_gene_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641260 p.Ile240Val missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiA 3641286 c.744C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiA 3641288 p.Glu249Gly missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiB 3641328 c.-207T>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641909 c.375T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3641918 c.384T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641924 c.390A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641928 c.394T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641933 c.399C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641945 c.411C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641961 p.Thr143Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641987 c.453C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641993 c.459A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3641999 c.465C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642533 c.999C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642542 c.1008A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642560 c.1026T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642569 c.1035C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642572 c.1038A>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642575 c.1041C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642578 c.1044C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642581 c.1047A>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiB 3642593 c.1059G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642602 c.1068A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642605 c.1071A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642609 p.Ser359Ala missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642614 c.1080C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiB 3642617 c.1083C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiB 3642630 p.Thr366Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642634 p.Asp367Gly missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642656 c.1122G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642683 c.1149C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642684 c.1150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642694 p.Ala387Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642701 c.1167C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642704 c.1170G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642719 c.1185T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642763 p.Asp410Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
alr 3840221 c.1200G>A synonymous_variant 1.0 cycloserine
alr 3840230 c.1191T>G synonymous_variant 1.0 cycloserine
alr 3840233 c.1188A>G synonymous_variant 1.0 cycloserine
alr 3840236 c.1185A>C synonymous_variant 1.0 cycloserine
alr 3840239 c.1182G>C synonymous_variant 1.0 cycloserine
alr 3840244 p.Ser393Gly missense_variant 1.0 cycloserine
alr 3840248 c.1173C>G synonymous_variant 1.0 cycloserine
alr 3840274 p.Val383Leu missense_variant 0.96 cycloserine
alr 3840275 c.1146T>G synonymous_variant 0.96 cycloserine
alr 3840278 c.1143T>C synonymous_variant 0.96 cycloserine
alr 3840287 c.1134C>T synonymous_variant 0.96 cycloserine
alr 3840293 c.1128T>G synonymous_variant 0.96 cycloserine
alr 3840296 c.1125G>C synonymous_variant 0.96 cycloserine
alr 3840305 c.1116T>C synonymous_variant 0.96 cycloserine
alr 3840309 p.Arg371Ala missense_variant 0.96 cycloserine
alr 3840312 p.Ile370Thr missense_variant 0.96 cycloserine
alr 3840328 c.1093T>C synonymous_variant 0.97 cycloserine
alr 3840329 c.1092T>C synonymous_variant 0.97 cycloserine
alr 3840356 c.1063_1065delCTTinsGC frameshift_variant&missense_variant 0.97 cycloserine
alr 3840360 p.Pro354Gln missense_variant 0.97 cycloserine
alr 3840380 c.1039_1041delATGinsCC frameshift_variant&missense_variant 0.94 cycloserine
alr 3840407 c.1014G>C synonymous_variant 0.93 cycloserine
alr 3840416 c.1003_1005delTGCinsCG frameshift_variant&missense_variant 0.91 cycloserine
alr 3840419 c.1002A>G synonymous_variant 0.91 cycloserine
alr 3840422 c.997_999delAGAinsGG frameshift_variant&synonymous_variant 0.91 cycloserine
alr 3840460 p.Ser321Thr missense_variant 0.97 cycloserine
alr 3840476 c.945A>G synonymous_variant 0.96 cycloserine
alr 3840482 c.939T>C synonymous_variant 0.95 cycloserine
alr 3840512 c.909C>T synonymous_variant 0.93 cycloserine
alr 3840515 p.Pro302Asp missense_variant 0.93 cycloserine
alr 3840518 c.903G>C synonymous_variant 0.93 cycloserine
alr 3840523 p.Ile300Val missense_variant 0.94 cycloserine
alr 3840527 c.894A>C synonymous_variant 0.94 cycloserine
alr 3840533 c.888G>A synonymous_variant 1.0 cycloserine
alr 3840539 c.882G>C synonymous_variant 1.0 cycloserine
alr 3840551 c.870G>C synonymous_variant 1.0 cycloserine
alr 3840554 c.865_867delGCGinsAC frameshift_variant&missense_variant 1.0 cycloserine
alr 3840557 c.864T>G synonymous_variant 1.0 cycloserine
alr 3840562 p.Ile287Val missense_variant 1.0 cycloserine
alr 3840575 c.846G>A synonymous_variant 1.0 cycloserine
alr 3840578 c.843T>C synonymous_variant 1.0 cycloserine
alr 3840584 c.837T>C synonymous_variant 1.0 cycloserine
alr 3840593 c.828C>G synonymous_variant 1.0 cycloserine
alr 3840605 c.814_816delGTGinsAA frameshift_variant&missense_variant 1.0 cycloserine
alr 3840627 p.Ala265Gly missense_variant 1.0 cycloserine
alr 3840632 c.789A>G synonymous_variant 1.0 cycloserine
alr 3840635 c.786G>C synonymous_variant 1.0 cycloserine
alr 3840641 c.780A>G synonymous_variant 1.0 cycloserine
alr 3840644 c.777G>C synonymous_variant 1.0 cycloserine
alr 3840647 c.774T>C synonymous_variant 1.0 cycloserine
alr 3840662 c.759G>C synonymous_variant 1.0 cycloserine
alr 3840944 c.477T>C synonymous_variant 1.0 cycloserine
alr 3840959 c.462G>C synonymous_variant 1.0 cycloserine
alr 3840974 c.447C>A synonymous_variant 1.0 cycloserine
alr 3840994 p.His143Asp missense_variant 1.0 cycloserine
alr 3840997 c.424T>C synonymous_variant 1.0 cycloserine
alr 3841001 c.420A>G synonymous_variant 1.0 cycloserine
alr 3841010 c.411A>G synonymous_variant 1.0 cycloserine
alr 3841013 c.408C>T synonymous_variant 1.0 cycloserine
alr 3841018 p.Leu135Val missense_variant 1.0 cycloserine
alr 3841028 c.393G>C synonymous_variant 1.0 cycloserine
alr 3841033 p.Val130Ile missense_variant 1.0 cycloserine
alr 3841036 p.Gln129Glu missense_variant 1.0 cycloserine
alr 3841055 c.366C>G synonymous_variant 1.0 cycloserine
alr 3841064 c.357C>T synonymous_variant 1.0 cycloserine
alr 3841094 c.325_327delGTGinsAC frameshift_variant&missense_variant 1.0 cycloserine
alr 3841100 c.321A>C synonymous_variant 1.0 cycloserine
alr 3841106 c.315T>C synonymous_variant 1.0 cycloserine
alr 3841109 c.312C>A synonymous_variant 1.0 cycloserine
alr 3841112 c.309T>C synonymous_variant 1.0 cycloserine
alr 3841115 c.306T>C synonymous_variant 1.0 cycloserine
alr 3841127 c.294A>G synonymous_variant 1.0 cycloserine
alr 3841130 c.291G>A synonymous_variant 1.0 cycloserine
alr 3841133 c.288G>A synonymous_variant 1.0 cycloserine
alr 3841154 c.267C>G synonymous_variant 1.0 cycloserine
alr 3841157 c.264A>G synonymous_variant 1.0 cycloserine
alr 3841343 c.-8963_77del frameshift_variant 0.97 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 1.0 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877567 p.Ser314Thr missense_variant 0.94 rifampicin
rpoA 3877569 c.939G>C synonymous_variant 0.94 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.97 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.97 rifampicin
rpoA 3877677 p.Ala277Ser missense_variant 0.96 rifampicin
rpoA 3877685 c.823C>T synonymous_variant 0.98 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>T synonymous_variant 1.0 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877818 c.690A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.98 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 1.0 rifampicin
rpoA 3877889 p.Ala207Ser missense_variant 0.99 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.98 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 0.98 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.98 rifampicin
rpoA 3877950 c.558C>T synonymous_variant 0.99 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>C synonymous_variant 1.0 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878046 c.462T>C synonymous_variant 1.0 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 1.0 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878361 c.147G>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878409 c.99C>G synonymous_variant 1.0 rifampicin
rpoA 3878430 c.78G>T synonymous_variant 1.0 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 1.0 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 1.0 rifampicin
rpoA 3878480 p.Ser10Ala missense_variant 1.0 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 1.0 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 1.0 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 1.0 rifampicin
rpoA 3878694 c.-187A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878714 c.-207C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878722 c.-215C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878725 c.-220_-218delCTAinsTG upstream_gene_variant 1.0 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878749 c.-242G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878769 c.-262C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878779 c.-272C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878785 c.-278T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878791 c.-284C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878806 c.-299C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878821 c.-314G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878830 c.-323G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 1.0 rifampicin
rpoA 3878869 c.-362G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878909 c.-402A>C upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878935 c.-428C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878953 c.-446C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878995 c.-488A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879002 c.-497_-496delGA upstream_gene_variant 1.0 rifampicin
rpoA 3879007 c.-501_-500insTC upstream_gene_variant 1.0 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879037 c.-530G>T upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879130 c.-623A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 1.0 rifampicin
ddn 3986627 c.-217C>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986636 c.-208C>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986637 c.-207C>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986654 c.-190C>A upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986696 c.-148G>C upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986984 c.141G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3986992 p.Thr50Ile missense_variant 1.0 delamanid
pretomanid
ddn 3987009 p.Thr56Ser missense_variant 1.0 delamanid
pretomanid
ddn 3987015 p.Gln58Glu missense_variant 1.0 delamanid
pretomanid
ddn 3987020 c.177G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987023 c.180G>A synonymous_variant 1.0 delamanid
pretomanid
ddn 3987026 c.183C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987028 p.Asn62Ser missense_variant 1.0 delamanid
pretomanid
ddn 3987035 c.192C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987038 c.195C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987041 c.198C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987055 p.Gly71Asp missense_variant 1.0 delamanid
pretomanid
ddn 3987062 c.219C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987065 c.222T>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987074 c.231C>A synonymous_variant 1.0 delamanid
pretomanid
ddn 3987077 c.234C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987083 c.240C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987086 c.243C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987091 p.Glu83Ala missense_variant 1.0 delamanid Uncertain significance
pretomanid
ddn 3987102 p.Met87Gln missense_variant 1.0 delamanid
pretomanid
ddn 3987128 c.285C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987137 c.294T>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987143 c.300A>G synonymous_variant 1.0 delamanid Not assoc w R - Interim
pretomanid
clpC1 4038212 c.2493T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038239 c.2466T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038248 c.2457C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038271 p.Pro812Thr missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2433T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2397G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038433 c.2272C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 1.0 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038559 p.Ile716Val missense_variant 1.0 pyrazinamide
clpC1 4038560 p.Asp715Glu missense_variant 1.0 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039031 c.1674T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039121 c.1584T>G synonymous_variant 0.98 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039145 c.1560G>T synonymous_variant 0.97 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.97 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.97 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4039268 c.1437C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039406 c.1299G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039574 c.1129_1131delGCGinsTC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039621 c.1084C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039679 c.1026C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039814 c.891C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.98 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039913 c.792C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039916 c.789T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039925 c.780C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.615T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040210 c.495G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.97 pyrazinamide
clpC1 4040219 c.486C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040234 c.471C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040336 c.369G>T synonymous_variant 0.97 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.97 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.91 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.92 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.92 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.95 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>A synonymous_variant 0.95 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.95 pyrazinamide
clpC1 4040486 c.219G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040596 c.109C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
panD 4044120 c.162A>C synonymous_variant 1.0 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 1.0 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 1.0 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>C synonymous_variant 1.0 pyrazinamide
panD 4044159 c.123C>T synonymous_variant 1.0 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 1.0 pyrazinamide
panD 4044165 c.117G>C synonymous_variant 1.0 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 1.0 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 1.0 pyrazinamide
panD 4044240 c.42G>C synonymous_variant 1.0 pyrazinamide
panD 4044264 c.18G>C synonymous_variant 1.0 pyrazinamide
panD 4044270 c.12G>C synonymous_variant 1.0 pyrazinamide
panD 4044642 c.-361C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044644 c.-363A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044647 c.-366C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044650 c.-369G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044656 c.-375G>A upstream_gene_variant 1.0 pyrazinamide
panD 4044662 c.-381C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044668 c.-387G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044671 c.-390G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044677 c.-396T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044682 c.-401C>A upstream_gene_variant 1.0 pyrazinamide
panD 4044686 c.-405C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044692 c.-411G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044713 c.-432G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044755 c.-474G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044758 c.-477C>T upstream_gene_variant 1.0 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 1.0 pyrazinamide
panD 4044785 c.-504C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.98 pyrazinamide
panD 4044809 c.-528C>G upstream_gene_variant 0.98 pyrazinamide
panD 4044812 c.-531A>G upstream_gene_variant 0.97 pyrazinamide
panD 4044818 c.-539_-537delCCGinsGC upstream_gene_variant 0.97 pyrazinamide
panD 4044822 c.-541G>C upstream_gene_variant 0.97 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044848 c.-567T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044854 c.-573A>C upstream_gene_variant 1.0 pyrazinamide
panD 4044860 c.-579C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044895 c.-614A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044896 c.-615T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044899 c.-618A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044904 c.-623A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044908 c.-628_-627delCTinsTG upstream_gene_variant 1.0 pyrazinamide
panD 4044914 c.-633A>G upstream_gene_variant 1.0 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044927 c.-646C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044929 c.-648G>T upstream_gene_variant 1.0 pyrazinamide
panD 4044935 c.-655_-654delAAinsTG upstream_gene_variant 1.0 pyrazinamide
panD 4044953 c.-673_-672delCGinsTC upstream_gene_variant 1.0 pyrazinamide
panD 4044959 c.-678C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044962 c.-681C>G upstream_gene_variant 1.0 pyrazinamide
panD 4044965 c.-684T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044977 c.-696T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045055 c.-774T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045063 c.-782T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045064 c.-783G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045073 c.-792C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 1.0 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 1.0 pyrazinamide
panD 4045112 c.-831A>G upstream_gene_variant 1.0 pyrazinamide
panD 4045115 c.-834G>C upstream_gene_variant 0.92 pyrazinamide
glpK 4138292 c.1464A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138298 c.1458G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138310 c.1446A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138323 p.Arg478Gln missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138328 c.1428T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138334 c.1422G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138337 p.Ala473Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138349 c.1407G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138364 c.1392G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138367 c.1389G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138376 p.Val460Ala missense_variant 1.0 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138382 c.1374A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138385 c.1371A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138424 c.1332T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138429 c.1327T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138442 c.1314C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138451 c.1305T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138464 p.Gly431Ala missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138466 c.1290C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138469 c.1287C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138475 c.1281C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138495 p.Gln421Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138496 c.1260G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 p.Glu413Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138547 c.1209C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138628 c.1128T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138685 c.1071C>A synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin
isoniazid
glpK 4138696 p.Pro354Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138709 c.1047G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138714 p.Ala348Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138715 c.1041G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138772 c.984G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138829 c.927A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138832 c.924C>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138835 c.921C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138841 c.915G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138847 c.909A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138858 p.Asn300His missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138859 c.897T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138862 c.894G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138871 c.885C>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138877 c.879A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138880 c.876T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138889 c.867G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138898 c.858T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138910 c.846G>T synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138913 c.843T>C synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139339 c.417G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139554 p.Ala68Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139570 c.186G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139576 c.180G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139600 c.156G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139603 c.153C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139608 p.Leu50Met missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139630 c.126C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139636 c.120C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139642 c.114G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139653 p.His35Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139663 c.93C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4238975 c.-888A>C upstream_gene_variant 1.0 ethambutol
embC 4238986 c.-877_-876delCAinsAG upstream_gene_variant 1.0 ethambutol
embC 4238999 c.-864C>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239023 c.-840C>A upstream_gene_variant 1.0 ethambutol
embC 4239027 c.-836A>G upstream_gene_variant 1.0 ethambutol
embC 4239032 c.-831T>C upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239033 c.-830C>A upstream_gene_variant 1.0 ethambutol
embC 4239057 c.-806A>G upstream_gene_variant 1.0 ethambutol
embC 4239062 c.-801C>G upstream_gene_variant 1.0 ethambutol
embC 4239065 c.-798G>C upstream_gene_variant 1.0 ethambutol
embC 4239068 c.-795A>C upstream_gene_variant 1.0 ethambutol
embC 4239069 c.-794_-792delTCAinsAG upstream_gene_variant 1.0 ethambutol
embC 4239076 c.-787C>T upstream_gene_variant 1.0 ethambutol
embC 4239079 c.-784_-783delCAinsGG upstream_gene_variant 0.96 ethambutol
embC 4239083 c.-780C>G upstream_gene_variant 0.96 ethambutol
embC 4239088 c.-775C>G upstream_gene_variant 0.96 ethambutol
embC 4239125 c.-738C>G upstream_gene_variant 0.94 ethambutol
embC 4239129 c.-734C>T upstream_gene_variant 0.84 ethambutol
embC 4239146 c.-717A>G upstream_gene_variant 0.83 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 0.8 ethambutol
embC 4239326 c.-537C>T upstream_gene_variant 0.92 ethambutol Uncertain significance
embC 4239336 c.-527T>C upstream_gene_variant 0.92 ethambutol
embC 4239344 c.-519G>C upstream_gene_variant 0.93 ethambutol
embC 4239350 c.-513G>C upstream_gene_variant 0.93 ethambutol
embC 4239398 c.-465G>T upstream_gene_variant 0.94 ethambutol
embC 4239401 c.-462A>G upstream_gene_variant 0.94 ethambutol
embC 4239404 c.-459G>A upstream_gene_variant 0.94 ethambutol Uncertain significance
embC 4239407 c.-456C>G upstream_gene_variant 0.91 ethambutol
embC 4239408 c.-455G>A upstream_gene_variant 0.94 ethambutol Uncertain significance
embC 4239413 c.-450C>G upstream_gene_variant 0.94 ethambutol
embC 4239426 c.-437_-435delCCAinsGC upstream_gene_variant 0.95 ethambutol
embC 4239432 c.-431A>G upstream_gene_variant 0.93 ethambutol
embC 4239437 c.-426T>C upstream_gene_variant 0.95 ethambutol Uncertain significance
embC 4239451 c.-412G>A upstream_gene_variant 0.97 ethambutol
embC 4239466 c.-397_-396delGCinsCG upstream_gene_variant 0.94 ethambutol
embC 4239469 c.-394G>C upstream_gene_variant 0.97 ethambutol Uncertain significance
embC 4239475 c.-388_-387delGGinsAA upstream_gene_variant 0.97 ethambutol
embC 4239479 c.-384C>G upstream_gene_variant 0.97 ethambutol
embC 4239482 c.-381C>G upstream_gene_variant 0.97 ethambutol
embC 4239486 c.-377T>A upstream_gene_variant 0.97 ethambutol
embC 4239512 c.-351G>C upstream_gene_variant 0.96 ethambutol Uncertain significance
embC 4239516 c.-347T>C upstream_gene_variant 0.92 ethambutol
embC 4239524 c.-339C>T upstream_gene_variant 0.96 ethambutol
embC 4239539 c.-324G>A upstream_gene_variant 0.94 ethambutol
embC 4239540 c.-323T>C upstream_gene_variant 0.94 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 0.94 ethambutol
embC 4240033 c.171G>C synonymous_variant 1.0 ethambutol
embC 4240048 c.186C>G synonymous_variant 1.0 ethambutol
embC 4240051 c.189A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240065 p.Ala68Glu missense_variant 1.0 ethambutol
embC 4240069 c.207T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240078 c.216A>G synonymous_variant 1.0 ethambutol
embC 4240090 c.228C>G synonymous_variant 1.0 ethambutol
embC 4240105 c.243C>T synonymous_variant 1.0 ethambutol
embC 4240111 c.249C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240120 c.258C>G synonymous_variant 1.0 ethambutol
embC 4240141 c.279A>G synonymous_variant 1.0 ethambutol
embC 4240154 c.293_301delAGAACACCG disruptive_inframe_deletion 1.0 ethambutol
embC 4240165 c.305_307delAGA disruptive_inframe_deletion 1.0 ethambutol
embC 4240178 c.316T>C synonymous_variant 1.0 ethambutol
embC 4240183 c.321A>G synonymous_variant 1.0 ethambutol
embC 4240201 c.339G>C synonymous_variant 1.0 ethambutol
embC 4240204 c.342T>G synonymous_variant 1.0 ethambutol
embC 4240211 p.Val117Ile missense_variant 1.0 ethambutol
embC 4240216 c.354T>C synonymous_variant 1.0 ethambutol
embC 4240228 c.366G>C synonymous_variant 1.0 ethambutol
embC 4240229 c.367_369delCTGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embC 4240234 c.372A>G synonymous_variant 1.0 ethambutol
embC 4240237 c.375G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240258 c.396T>G synonymous_variant 1.0 ethambutol
embC 4240264 c.402G>C synonymous_variant 1.0 ethambutol
embC 4240267 c.405T>C synonymous_variant 1.0 ethambutol
embC 4240270 c.408T>C synonymous_variant 1.0 ethambutol
embC 4240273 c.411C>T synonymous_variant 1.0 ethambutol
embC 4240277 p.Leu139Val missense_variant 1.0 ethambutol
embC 4240292 c.430C>T synonymous_variant 1.0 ethambutol
embC 4240297 c.435T>C synonymous_variant 1.0 ethambutol
embC 4240313 p.Thr151Ala missense_variant 1.0 ethambutol
embC 4240318 c.456T>C synonymous_variant 1.0 ethambutol
embC 4240325 c.463T>C synonymous_variant 1.0 ethambutol
embC 4240330 c.468A>G synonymous_variant 1.0 ethambutol
embC 4240348 c.486T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240355 c.493_495delGCCinsAG frameshift_variant&missense_variant 1.0 ethambutol
embC 4240372 c.510A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240376 p.Val172Thr missense_variant 1.0 ethambutol
embC 4240381 c.519G>A synonymous_variant 1.0 ethambutol
embC 4240384 c.522A>G synonymous_variant 1.0 ethambutol
embC 4240390 c.528T>C synonymous_variant 1.0 ethambutol
embC 4240393 c.531T>C synonymous_variant 1.0 ethambutol
embC 4240399 c.537C>T synonymous_variant 1.0 ethambutol
embC 4240405 c.543T>C synonymous_variant 1.0 ethambutol
embC 4240406 c.544_546delGCAinsTG frameshift_variant&stop_gained 1.0 ethambutol
embC 4240424 p.Arg188Lys missense_variant 0.95 ethambutol
embC 4240459 c.597G>C synonymous_variant 0.95 ethambutol
embC 4240471 c.609C>T synonymous_variant 0.93 ethambutol
embC 4240632 p.Met257Thr missense_variant 1.0 ethambutol
embC 4240642 c.780G>C synonymous_variant 1.0 ethambutol
embC 4240655 p.Ala265Pro missense_variant 1.0 ethambutol
embC 4240660 c.798C>T synonymous_variant 1.0 ethambutol
embC 4240669 c.807G>C synonymous_variant 1.0 ethambutol
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4240685 p.Thr275Gly missense_variant 1.0 ethambutol
embC 4240690 c.828G>C synonymous_variant 1.0 ethambutol
embC 4240693 c.831T>C synonymous_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240786 c.924C>T synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240807 c.945C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240816 c.954C>T synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>G synonymous_variant 1.0 ethambutol
embC 4240828 c.966G>C synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>A synonymous_variant 1.0 ethambutol
embC 4240858 c.996G>C synonymous_variant 1.0 ethambutol
embC 4240867 c.1005T>A synonymous_variant 1.0 ethambutol
embC 4240870 c.1008T>C synonymous_variant 1.0 ethambutol
embC 4240879 c.1017G>C synonymous_variant 1.0 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.98 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.98 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.98 ethambutol Not assoc w R
embC 4240898 c.1036C>T synonymous_variant 0.98 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.98 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.98 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.99 ethambutol
embC 4240957 c.1095C>G synonymous_variant 1.0 ethambutol
embC 4240960 c.1098G>C synonymous_variant 1.0 ethambutol
embC 4240966 c.1104G>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240969 c.1107C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240979 p.Thr373Gln missense_variant 1.0 ethambutol
embC 4240990 c.1128A>C synonymous_variant 1.0 ethambutol
embC 4241002 c.1140G>C synonymous_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 1.0 ethambutol
embC 4241023 c.1161T>G synonymous_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241071 c.1209C>G synonymous_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241158 c.1296T>C synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241167 c.1305C>G synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.97 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.94 ethambutol
embC 4241374 c.1512T>C synonymous_variant 1.0 ethambutol
embC 4241380 c.1518A>C synonymous_variant 1.0 ethambutol
embC 4241394 p.Lys511Ser missense_variant 1.0 ethambutol
embC 4241411 p.Ile517Leu missense_variant 1.0 ethambutol
embC 4241449 c.1587C>A synonymous_variant 0.98 ethambutol
embC 4241455 c.1593C>T synonymous_variant 1.0 ethambutol
embC 4241470 c.1608C>G synonymous_variant 1.0 ethambutol
embC 4241479 c.1617C>G synonymous_variant 1.0 ethambutol
embC 4241496 p.Ala545Gly missense_variant 1.0 ethambutol
embC 4241498 p.Val546Ile missense_variant 1.0 ethambutol
embC 4241501 p.Ser547Thr missense_variant 1.0 ethambutol
embC 4241518 c.1656A>G synonymous_variant 1.0 ethambutol
embC 4241521 c.1659T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>A synonymous_variant 0.97 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.96 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embC 4241542 c.1680C>G synonymous_variant 0.96 ethambutol
embC 4241545 c.1683T>G synonymous_variant 0.96 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.96 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.96 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.95 ethambutol
embC 4241572 c.1710C>A synonymous_variant 0.93 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.92 ethambutol
embC 4241648 c.1786T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embC 4241656 c.1794G>A synonymous_variant 0.94 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.94 ethambutol
embC 4241671 c.1809T>G synonymous_variant 0.95 ethambutol
embC 4241707 c.1845G>C synonymous_variant 1.0 ethambutol
embC 4241713 c.1851G>C synonymous_variant 1.0 ethambutol
embC 4241719 c.1857G>C synonymous_variant 1.0 ethambutol
embC 4241736 p.Val625Ala missense_variant 1.0 ethambutol Uncertain significance
embC 4241741 c.1879_1881delGTCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embC 4241747 p.Val629Leu missense_variant 1.0 ethambutol
embC 4241750 c.1888_1890delTTGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embC 4241755 c.1893C>G synonymous_variant 1.0 ethambutol
embC 4241770 c.1908T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241791 c.1929G>A synonymous_variant 1.0 ethambutol
embC 4241797 c.1935C>T synonymous_variant 1.0 ethambutol
embC 4241800 c.1938C>T synonymous_variant 1.0 ethambutol
embC 4242128 p.Leu756Met missense_variant 0.91 ethambutol
embC 4242138 p.Leu759Pro missense_variant 0.77 ethambutol
embC 4242148 c.2286C>T synonymous_variant 0.77 ethambutol Not assoc w R - Interim
embC 4242151 c.2289A>C synonymous_variant 0.77 ethambutol
embC 4242158 c.2296C>T synonymous_variant 0.77 ethambutol
embC 4242161 p.Ala767Pro missense_variant 0.8 ethambutol
embC 4242171 p.Thr770Ser missense_variant 0.83 ethambutol
embC 4242176 p.Pro772Ser missense_variant 0.83 ethambutol Uncertain significance
embC 4242179 p.Leu773Val missense_variant 0.83 ethambutol
embC 4242199 c.2337C>G synonymous_variant 0.87 ethambutol
embC 4242202 c.2340C>T synonymous_variant 0.87 ethambutol
embC 4242203 c.2341C>T synonymous_variant 0.87 ethambutol
embC 4242208 c.2346T>G synonymous_variant 0.87 ethambutol
embC 4242220 c.2358A>C synonymous_variant 0.86 ethambutol
embC 4242245 p.Thr795Arg missense_variant 0.89 ethambutol
embA 4242265 c.-968A>G upstream_gene_variant 0.87 ethambutol
embA 4242271 c.-962A>G upstream_gene_variant 0.83 ethambutol
embA 4242274 c.-959G>C upstream_gene_variant 0.82 ethambutol
embA 4242277 c.-956T>C upstream_gene_variant 0.82 ethambutol
embC 4242280 c.2418C>T synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embC 4242283 c.2421T>C synonymous_variant 0.82 ethambutol Not assoc w R - Interim
embA 4242286 c.-947C>T upstream_gene_variant 0.82 ethambutol
embC 4242287 p.Leu809Ile missense_variant 0.82 ethambutol
embA 4242427 c.-806A>G upstream_gene_variant 0.9 ethambutol
embC 4242428 p.Ala856Ser missense_variant 0.9 ethambutol Uncertain significance
embC 4242434 c.2572_2574delGTGinsAC frameshift_variant&missense_variant 0.9 ethambutol
embC 4242449 p.Met863Arg missense_variant 0.91 ethambutol
embA 4242647 c.-586C>T upstream_gene_variant 0.92 ethambutol
embA 4242652 c.-581C>G upstream_gene_variant 0.92 ethambutol
embC 4242653 p.Ala931Leu missense_variant 0.92 ethambutol
embA 4242658 c.-575A>G upstream_gene_variant 0.92 ethambutol
embC 4242661 c.2799G>A synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embA 4242667 c.-566C>G upstream_gene_variant 0.92 ethambutol
embC 4242674 p.Ser938Ala missense_variant 0.92 ethambutol
embA 4242688 c.-545G>A upstream_gene_variant 0.92 ethambutol
embC 4242689 p.Val943Ile missense_variant 0.92 ethambutol Uncertain significance
embA 4242694 c.-539G>C upstream_gene_variant 0.92 ethambutol
embA 4242695 c.-538T>C upstream_gene_variant 0.92 ethambutol
embC 4242710 c.2848_2850delCAGinsGA frameshift_variant&missense_variant 1.0 ethambutol
embC 4242715 c.2853T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4242739 c.-494C>G upstream_gene_variant 1.0 ethambutol
embA 4242742 c.-491C>T upstream_gene_variant 1.0 ethambutol
embA 4242745 c.-488A>C upstream_gene_variant 1.0 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 1.0 ethambutol
embC 4242764 p.Val968Leu missense_variant 1.0 ethambutol
embC 4242779 c.2917_2919delAACinsGT frameshift_variant&missense_variant 1.0 ethambutol
embC 4242787 c.2925G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4242790 c.2928_2929delCGinsTTCC frameshift_variant&missense_variant 1.0 ethambutol
embC 4242794 c.2932_2934delGCGinsC frameshift_variant&missense_variant 1.0 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 1.0 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 1.0 ethambutol
embA 4242826 c.-407G>T upstream_gene_variant 1.0 ethambutol
embA 4242832 c.-401A>G upstream_gene_variant 1.0 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 0.96 ethambutol
embA 4242847 c.-386C>A upstream_gene_variant 0.95 ethambutol
embA 4244111 c.879C>T synonymous_variant 1.0 ethambutol
embA 4244117 c.885G>C synonymous_variant 1.0 ethambutol
embA 4244120 c.888T>C synonymous_variant 1.0 ethambutol
embA 4244126 c.894C>G synonymous_variant 1.0 ethambutol
embA 4244135 p.Glu301Asp missense_variant 1.0 ethambutol
embA 4244154 c.922_924delACAinsC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244165 c.933T>G synonymous_variant 1.0 ethambutol
embA 4244166 p.Ala312Ser missense_variant 1.0 ethambutol
embA 4244169 p.Gln313Lys missense_variant 1.0 ethambutol
embA 4244172 c.940C>T synonymous_variant 1.0 ethambutol
embA 4244198 c.966C>G synonymous_variant 1.0 ethambutol
embA 4244207 c.975C>G synonymous_variant 1.0 ethambutol
embA 4244213 c.981C>G synonymous_variant 1.0 ethambutol
embA 4244219 c.987C>G synonymous_variant 1.0 ethambutol
embA 4244228 c.996A>G synonymous_variant 1.0 ethambutol
embA 4244234 c.1002C>G synonymous_variant 1.0 ethambutol
embA 4244247 p.Val339Ile missense_variant 1.0 ethambutol
embA 4244372 c.1140T>G synonymous_variant 1.0 ethambutol
embA 4244390 c.1158G>C synonymous_variant 1.0 ethambutol
embA 4244393 c.1161G>C synonymous_variant 1.0 ethambutol
embA 4244396 c.1164T>C synonymous_variant 1.0 ethambutol
embA 4244398 p.Val389Ala missense_variant 1.0 ethambutol
embA 4244402 c.1170G>C synonymous_variant 1.0 ethambutol
embA 4244408 c.1176G>C synonymous_variant 1.0 ethambutol
embA 4244412 p.Val394Met missense_variant 1.0 ethambutol
embA 4244415 c.1183T>C synonymous_variant 1.0 ethambutol
embA 4244426 c.1194G>C synonymous_variant 1.0 ethambutol
embA 4244427 p.Ser399Ala missense_variant 1.0 ethambutol
embA 4244438 c.1206C>G synonymous_variant 1.0 ethambutol
embA 4244439 p.Gly403Arg missense_variant 1.0 ethambutol Uncertain significance
embA 4244459 c.1227G>C synonymous_variant 1.0 ethambutol
embA 4244462 c.1230A>C synonymous_variant 1.0 ethambutol
embA 4244465 c.1233C>G synonymous_variant 1.0 ethambutol
embA 4244567 c.1335C>G synonymous_variant 0.85 ethambutol
embA 4244573 c.1341G>C synonymous_variant 0.93 ethambutol
embA 4244585 c.1353A>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embA 4244588 c.1356G>A synonymous_variant 0.95 ethambutol
embA 4244611 p.Ala460Val missense_variant 0.97 ethambutol
embA 4244615 c.1383G>C synonymous_variant 0.97 ethambutol
embA 4244616 p.Ala462Ser missense_variant 0.97 ethambutol
embA 4244633 c.1401C>G synonymous_variant 0.97 ethambutol
embA 4244645 c.1413T>C synonymous_variant 0.97 ethambutol
embA 4244648 c.1416G>C synonymous_variant 0.97 ethambutol
embA 4244649 p.Asp473Ser missense_variant 0.97 ethambutol
embA 4244669 c.1437G>C synonymous_variant 1.0 ethambutol
embA 4244675 c.1443A>G synonymous_variant 1.0 ethambutol
embA 4244681 c.1449A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244708 c.1476C>G synonymous_variant 1.0 ethambutol
embA 4244726 p.Asp498Glu missense_variant 1.0 ethambutol
embA 4244728 p.Phe499Trp missense_variant 1.0 ethambutol
embA 4244747 c.1515T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244756 c.1524G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4244764 p.Val511Ala missense_variant 1.0 ethambutol
embA 4244771 c.1539G>T synonymous_variant 0.95 ethambutol
embA 4244780 c.1548C>G synonymous_variant 1.0 ethambutol
embA 4244783 c.1551C>G synonymous_variant 1.0 ethambutol
embA 4244792 c.1560G>C synonymous_variant 1.0 ethambutol
embA 4244802 p.Leu524Met missense_variant 1.0 ethambutol
embA 4244808 c.1576_1578delTTCinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244823 p.Val531Met missense_variant 1.0 ethambutol
embA 4244829 c.1597_1599delTTCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4244843 c.1611G>C synonymous_variant 1.0 ethambutol
embA 4244855 c.1623G>T synonymous_variant 1.0 ethambutol
embA 4244856 p.Ala542Pro missense_variant 1.0 ethambutol
embA 4244861 c.1629G>C synonymous_variant 1.0 ethambutol
embA 4244867 c.1635C>G synonymous_variant 0.96 ethambutol
embA 4244873 c.1641C>T synonymous_variant 0.96 ethambutol
embA 4244879 c.1647C>G synonymous_variant 0.96 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.96 ethambutol
embA 4244897 c.1665T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 0.95 ethambutol
embA 4244918 c.1686G>A synonymous_variant 0.94 ethambutol
embA 4244921 c.1689C>G synonymous_variant 0.95 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.96 ethambutol
embA 4244936 c.1704C>G synonymous_variant 0.96 ethambutol
embA 4244970 p.Leu580Val missense_variant 0.95 ethambutol
embA 4244978 c.1746G>C synonymous_variant 0.94 ethambutol
embA 4244980 p.Val583Ala missense_variant 0.94 ethambutol
embA 4244982 c.1750T>C synonymous_variant 0.94 ethambutol
embA 4244987 c.1755T>C synonymous_variant 0.95 ethambutol
embA 4244999 c.1767G>C synonymous_variant 0.95 ethambutol
embA 4245005 c.1773C>G synonymous_variant 0.95 ethambutol
embA 4245006 c.1774_1776delTTTinsCG frameshift_variant&missense_variant 0.95 ethambutol Uncertain significance
embA 4245020 c.1788T>C synonymous_variant 1.0 ethambutol
embA 4245023 c.1791A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245026 c.1794T>C synonymous_variant 1.0 ethambutol
embA 4245029 c.1797T>C synonymous_variant 1.0 ethambutol
embA 4245032 c.1800A>C synonymous_variant 1.0 ethambutol
embA 4245041 c.1809C>G synonymous_variant 1.0 ethambutol
embA 4245053 c.1821G>T synonymous_variant 1.0 ethambutol
embA 4245056 c.1824C>G synonymous_variant 1.0 ethambutol
embA 4245078 p.Trp616Val missense_variant 1.0 ethambutol
embA 4245083 c.1851A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245092 c.1860C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245093 c.1861_1863delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245108 p.Tyr626Asp missense_variant 1.0 ethambutol
embA 4245114 p.Gly628Asn missense_variant 1.0 ethambutol
embA 4245125 c.1893G>C synonymous_variant 1.0 ethambutol
embA 4245128 c.1896G>C synonymous_variant 1.0 ethambutol
embA 4245137 c.1905T>C synonymous_variant 1.0 ethambutol
embA 4245145 p.Gln638Pro missense_variant 1.0 ethambutol
embA 4245149 c.1917C>G synonymous_variant 1.0 ethambutol
embA 4245153 p.Ile641Val missense_variant 1.0 ethambutol
embA 4245158 c.1926C>G synonymous_variant 1.0 ethambutol
embA 4245161 c.1929C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245182 c.1950T>C synonymous_variant 1.0 ethambutol
embA 4245206 c.1974A>G synonymous_variant 0.97 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.97 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.97 ethambutol
embA 4245217 p.Ala662Gly missense_variant 0.97 ethambutol
embA 4245233 c.2001G>C synonymous_variant 0.98 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.98 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embA 4245282 c.2050_2052delATCinsGG frameshift_variant&missense_variant 0.97 ethambutol Uncertain significance
embA 4245285 c.2053T>C synonymous_variant 0.97 ethambutol
embA 4245293 c.2061T>C synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embA 4245296 c.2064G>C synonymous_variant 0.97 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.97 ethambutol
embA 4245315 p.Val695Thr missense_variant 0.97 ethambutol
embA 4245327 p.Ala699Leu missense_variant 0.96 ethambutol
embA 4245338 c.2106C>G synonymous_variant 0.96 ethambutol
embA 4245340 p.Gly703Ala missense_variant 0.96 ethambutol
embA 4245345 p.Met705Leu missense_variant 0.96 ethambutol
embA 4245355 p.Ala708Gly missense_variant 0.88 ethambutol
embA 4245368 c.2136T>C synonymous_variant 0.88 ethambutol
embA 4245377 c.2145T>C synonymous_variant 0.8 ethambutol
embA 4245449 c.2217G>C synonymous_variant 0.8 ethambutol
embA 4245461 c.2229C>G synonymous_variant 0.89 ethambutol
embA 4245472 p.Ala747Val missense_variant 0.91 ethambutol
embA 4245477 p.Met749Leu missense_variant 0.92 ethambutol
embA 4245489 p.Val753Leu missense_variant 0.94 ethambutol
embA 4245497 c.2265C>A synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embA 4245509 c.2277A>G synonymous_variant 1.0 ethambutol
embA 4245513 p.Asp761Tyr missense_variant 1.0 ethambutol
embB 4245518 c.-996A>G upstream_gene_variant 1.0 ethambutol
embA 4245524 c.2292G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245527 c.-987C>G upstream_gene_variant 1.0 ethambutol
embB 4245530 c.-984T>C upstream_gene_variant 1.0 ethambutol
embA 4245531 p.Ile767Val missense_variant 1.0 ethambutol
embA 4245535 p.Ser768Asn missense_variant 1.0 ethambutol
embA 4245569 p.Glu779Asp missense_variant 1.0 ethambutol
embB 4245575 c.-939C>G upstream_gene_variant 1.0 ethambutol
embB 4245593 c.-921C>G upstream_gene_variant 0.98 ethambutol
embA 4245594 p.Ser788Thr missense_variant 0.98 ethambutol
embB 4245620 c.-894T>C upstream_gene_variant 0.98 ethambutol
embB 4245623 c.-891G>T upstream_gene_variant 0.98 ethambutol
embA 4245641 c.2409C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245643 p.Ala804Val missense_variant 0.97 ethambutol
embA 4245648 p.Ile806Phe missense_variant 0.97 ethambutol
embA 4245652 p.Thr807Ser missense_variant 0.97 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.98 ethambutol
embB 4245692 c.-822G>C upstream_gene_variant 0.98 ethambutol
embA 4245693 c.2461_2463delATCinsGG frameshift_variant&missense_variant 0.98 ethambutol Uncertain significance
embB 4245719 c.-795G>A upstream_gene_variant 0.98 ethambutol
embB 4245725 c.-789A>C upstream_gene_variant 0.98 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.97 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.98 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 1.0 ethambutol
embB 4245743 c.-771C>A upstream_gene_variant 1.0 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 1.0 ethambutol
embB 4245767 c.-747G>A upstream_gene_variant 1.0 ethambutol
embA 4245772 p.Asn847Thr missense_variant 1.0 ethambutol
embB 4245782 c.-732C>G upstream_gene_variant 1.0 ethambutol
embA 4245785 c.2553G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245788 c.-726C>G upstream_gene_variant 1.0 ethambutol
embA 4245795 p.Ala855Thr missense_variant 1.0 ethambutol
embA 4245805 p.Gln858Arg missense_variant 1.0 ethambutol Uncertain significance
embB 4245809 c.-705A>G upstream_gene_variant 1.0 ethambutol
embB 4245815 c.-699C>G upstream_gene_variant 1.0 ethambutol
embA 4245820 p.Ser863Thr missense_variant 1.0 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 1.0 ethambutol
embB 4246184 c.-330A>C upstream_gene_variant 1.0 ethambutol
embB 4246187 c.-327C>G upstream_gene_variant 1.0 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 1.0 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 1.0 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 1.0 ethambutol
embA 4246220 c.2988T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 1.0 ethambutol
embA 4246235 c.3003G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246244 c.-270G>A upstream_gene_variant 1.0 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 1.0 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 1.0 ethambutol
embB 4246268 c.-246G>A upstream_gene_variant 1.0 ethambutol
embB 4246277 c.-237G>C upstream_gene_variant 1.0 ethambutol
embB 4246280 c.-234G>C upstream_gene_variant 1.0 ethambutol
embB 4246292 c.-222A>G upstream_gene_variant 1.0 ethambutol
embA 4246299 p.Ser1023Ala missense_variant 1.0 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 1.0 ethambutol
embB 4246316 c.-198T>C upstream_gene_variant 1.0 ethambutol
embB 4246352 c.-162G>C upstream_gene_variant 1.0 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4246373 c.-141T>C upstream_gene_variant 1.0 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 1.0 ethambutol
embB 4246385 c.-129T>C upstream_gene_variant 1.0 ethambutol
embB 4246400 c.-114G>C upstream_gene_variant 1.0 ethambutol
embA 4246413 p.His1061Tyr missense_variant 1.0 ethambutol
embA 4246419 c.3187C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4246435 p.Gln1068Arg missense_variant 1.0 ethambutol
embB 4246439 c.-75T>G upstream_gene_variant 1.0 ethambutol
embA 4246442 c.3210A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246451 c.-63T>C upstream_gene_variant 1.0 ethambutol
embA 4246458 p.Glu1076Arg missense_variant 1.0 ethambutol
embB 4246463 c.-51C>T upstream_gene_variant 1.0 ethambutol
embB 4246472 c.-42T>C upstream_gene_variant 1.0 ethambutol
embB 4247365 c.852A>C synonymous_variant 0.92 ethambutol
embB 4247371 c.858C>G synonymous_variant 0.93 ethambutol
embB 4247380 c.867C>G synonymous_variant 0.94 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.95 ethambutol
embB 4247404 c.891G>C synonymous_variant 0.96 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.97 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4247470 c.957T>C synonymous_variant 0.97 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.97 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.97 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.97 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.98 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.98 ethambutol
embB 4247550 p.Ala346Asp missense_variant 0.98 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.98 ethambutol
embB 4247566 c.1053C>G synonymous_variant 0.98 ethambutol
embB 4247567 c.1054C>T synonymous_variant 0.98 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.98 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embB 4247602 c.1089G>A synonymous_variant 0.95 ethambutol
embB 4247629 c.1116C>G synonymous_variant 0.94 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.94 ethambutol
embB 4247645 p.Glu378Thr missense_variant 0.88 ethambutol
embB 4247650 c.1137C>G synonymous_variant 0.88 ethambutol
embB 4247656 c.1143A>G synonymous_variant 0.88 ethambutol
embB 4247657 p.Pro382Ala missense_variant 0.88 ethambutol
embB 4247662 c.1149C>G synonymous_variant 0.88 ethambutol
embB 4247674 c.1161G>C synonymous_variant 0.88 ethambutol
embB 4247684 c.1171T>C synonymous_variant 0.89 ethambutol
embB 4247746 c.1233C>T synonymous_variant 0.82 ethambutol
embB 4247749 c.1236G>A synonymous_variant 0.9 ethambutol
embB 4247816 p.Val435Ile missense_variant 1.0 ethambutol
embB 4247821 c.1308T>C synonymous_variant 1.0 ethambutol
embB 4247827 c.1314C>G synonymous_variant 1.0 ethambutol
embB 4247830 c.1317A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247842 c.1329T>C synonymous_variant 1.0 ethambutol
embB 4247857 c.1344C>G synonymous_variant 1.0 ethambutol
embB 4247881 c.1368G>C synonymous_variant 1.0 ethambutol
embB 4247887 c.1374C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 1.0 ethambutol
embB 4247897 c.1384_1386delATGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247905 c.1392G>A synonymous_variant 1.0 ethambutol
embB 4247914 c.1401G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247916 p.Arg468His missense_variant 1.0 ethambutol Uncertain significance
embB 4247920 c.1407T>C synonymous_variant 1.0 ethambutol
embB 4247940 p.Leu476Trp missense_variant 1.0 ethambutol
embB 4247945 c.1432T>C synonymous_variant 1.0 ethambutol
embB 4247951 c.1438_1440delTCGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embB 4247957 p.Met482Leu missense_variant 1.0 ethambutol
embB 4247965 c.1452C>G synonymous_variant 1.0 ethambutol
embB 4247971 c.1458C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247972 p.Thr487Ser missense_variant 1.0 ethambutol
embB 4247983 c.1470G>C synonymous_variant 1.0 ethambutol
embB 4248007 c.1494C>T synonymous_variant 0.96 ethambutol
embB 4248011 p.Ser500Arg missense_variant 1.0 ethambutol
embB 4248014 p.Thr501Ala missense_variant 1.0 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.97 ethambutol
embB 4248041 p.Ala510Asn missense_variant 0.97 ethambutol
embB 4248044 c.1531_1533delAAAinsGG frameshift_variant&missense_variant 0.97 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.97 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.98 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.97 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.97 ethambutol
embB 4248121 c.1608G>A synonymous_variant 0.97 ethambutol
embB 4248133 c.1620C>A synonymous_variant 0.98 ethambutol
embB 4248143 c.1630_1632delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol
embB 4248157 c.1644A>C synonymous_variant 1.0 ethambutol
embB 4248173 p.Val554Met missense_variant 1.0 ethambutol
embB 4248178 c.1665C>T synonymous_variant 1.0 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 1.0 ethambutol
embB 4248220 c.1707A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248283 c.1770C>G synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>T synonymous_variant 1.0 ethambutol
embB 4248343 c.1830G>C synonymous_variant 1.0 ethambutol
embB 4248349 c.1836G>C synonymous_variant 1.0 ethambutol
embB 4248382 c.1869C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248457 c.1944T>C synonymous_variant 1.0 ethambutol
embB 4249354 c.2841G>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
embB 4249369 c.2856T>C synonymous_variant 1.0 ethambutol
embB 4249375 c.2862G>C synonymous_variant 1.0 ethambutol
embB 4249381 c.2868A>G synonymous_variant 1.0 ethambutol
embB 4249387 c.2874G>A synonymous_variant 1.0 ethambutol
embB 4249417 c.2904A>G synonymous_variant 1.0 ethambutol
embB 4249420 c.2907G>C synonymous_variant 1.0 ethambutol
embB 4249423 p.Asp970Glu missense_variant 1.0 ethambutol Uncertain significance
embB 4249432 c.2919A>G synonymous_variant 1.0 ethambutol
embB 4249441 c.2928A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 1.0 ethambutol
embB 4249447 c.2934G>C synonymous_variant 1.0 ethambutol
embB 4249454 p.Thr981Ser missense_variant 1.0 ethambutol
embB 4249459 c.2946G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249486 c.2973T>G synonymous_variant 0.98 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.98 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.98 ethambutol
embB 4249504 c.2991G>A synonymous_variant 0.97 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.96 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.96 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.96 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.97 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.97 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.96 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.96 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.97 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.96 ethambutol
embB 4249600 c.3087A>G synonymous_variant 0.96 ethambutol
embB 4249609 c.3096T>C synonymous_variant 0.96 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.96 ethambutol
embB 4249640 c.3127T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249661 p.Ala1050Ser missense_variant 0.96 ethambutol
embB 4249666 c.3153C>G synonymous_variant 0.96 ethambutol
embB 4249675 c.3162C>T synonymous_variant 0.95 ethambutol
embB 4249686 p.Ala1058Gly missense_variant 0.94 ethambutol
embB 4249690 c.3177C>T synonymous_variant 0.94 ethambutol
embB 4249693 c.3180T>C synonymous_variant 0.94 ethambutol
embB 4249699 c.3186T>G synonymous_variant 0.93 ethambutol
embB 4249702 c.3189C>G synonymous_variant 0.93 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.93 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4268105 c.732T>C synonymous_variant 0.93 ethambutol
aftB 4268117 c.720G>C synonymous_variant 0.93 ethambutol
aftB 4268123 c.712_714delAGTinsGC frameshift_variant&synonymous_variant 0.93 ethambutol Uncertain significance
aftB 4268126 c.711G>C synonymous_variant 0.87 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.93 ethambutol
aftB 4268138 c.699A>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4268144 c.693T>C synonymous_variant 0.94 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.94 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.94 ethambutol
aftB 4268179 c.658T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
aftB 4268194 p.Leu215Val missense_variant 0.92 ethambutol
aftB 4268353 p.Leu162Val missense_variant 1.0 ethambutol
aftB 4268360 c.477A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268369 c.468C>G synonymous_variant 1.0 ethambutol
aftB 4268386 c.451T>C synonymous_variant 1.0 ethambutol
aftB 4268389 c.448C>T synonymous_variant 1.0 ethambutol
aftB 4268390 c.447G>A synonymous_variant 1.0 ethambutol
aftB 4268396 c.441T>C synonymous_variant 1.0 ethambutol
aftB 4268404 c.433T>C synonymous_variant 1.0 ethambutol
aftB 4268406 p.Val144Thr missense_variant 1.0 ethambutol
aftB 4268444 c.393C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268450 c.387A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268455 p.Val128Leu missense_variant 1.0 ethambutol
aftB 4268461 p.Ile126Val missense_variant 1.0 ethambutol Uncertain significance
aftB 4268462 c.375T>C synonymous_variant 1.0 ethambutol
aftB 4268465 c.372A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268470 c.367C>T synonymous_variant 1.0 ethambutol
aftB 4268480 c.357G>C synonymous_variant 1.0 ethambutol
aftB 4268483 c.354T>G synonymous_variant 1.0 ethambutol
aftB 4268985 c.-149A>G upstream_gene_variant 0.9 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
aftB 4269000 c.-164G>T upstream_gene_variant 0.91 ethambutol
ubiA 4269003 c.831C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.91 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.92 ethambutol
aftB 4269027 c.-191C>G upstream_gene_variant 0.94 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 0.94 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269051 c.783C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269060 c.-224G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 1.0 ethambutol
ubiA 4269099 c.728_735delACAGCGGGinsCGGGA missense_variant&disruptive_inframe_deletion 1.0 ethambutol
ubiA 4269110 c.723dupC frameshift_variant 1.0 ethambutol
aftB 4269114 c.-278C>T upstream_gene_variant 1.0 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 1.0 ethambutol
ubiA 4269143 p.Leu231Val missense_variant 1.0 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269153 c.-317C>G upstream_gene_variant 1.0 ethambutol
aftB 4269171 c.-335C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269177 c.657G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269183 c.-347T>C upstream_gene_variant 1.0 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 1.0 ethambutol
aftB 4269206 c.-370C>T upstream_gene_variant 1.0 ethambutol
ubiA 4269207 c.625_627delTCGinsGC frameshift_variant&missense_variant 1.0 ethambutol
aftB 4269216 c.-380C>A upstream_gene_variant 1.0 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 1.0 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 1.0 ethambutol
ubiA 4269243 p.His197Gln missense_variant 1.0 ethambutol
aftB 4269255 c.-419C>T upstream_gene_variant 1.0 ethambutol
aftB 4269258 c.-422C>T upstream_gene_variant 1.0 ethambutol
aftB 4269261 c.-425G>A upstream_gene_variant 1.0 ethambutol
aftB 4269282 c.-446G>A upstream_gene_variant 1.0 ethambutol
aftB 4269285 c.-449T>G upstream_gene_variant 1.0 ethambutol
aftB 4269291 c.-455A>C upstream_gene_variant 1.0 ethambutol
ubiA 4269294 c.538_540delATGinsGC frameshift_variant&missense_variant 1.0 ethambutol
ubiA 4269299 p.Ile179Phe missense_variant 1.0 ethambutol
aftB 4269306 c.-470T>C upstream_gene_variant 1.0 ethambutol
ubiA 4269314 p.Lys174Gln missense_variant 1.0 ethambutol
ubiA 4269315 c.519C>G synonymous_variant 0.91 ethambutol Not assoc w R - Interim
ubiA 4269321 c.513G>A synonymous_variant 0.91 ethambutol Not assoc w R - Interim
ubiA 4269327 c.505_507delAAAinsGT frameshift_variant&missense_variant 0.91 ethambutol
ubiA 4269337 p.Val166Ala missense_variant 0.82 ethambutol
ubiA 4269339 c.495C>T synonymous_variant 0.91 ethambutol Not assoc w R - Interim
aftB 4269351 c.-515C>G upstream_gene_variant 1.0 ethambutol
aftB 4269354 c.-518C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269359 p.Ile159Leu missense_variant 1.0 ethambutol
aftB 4269362 c.-526T>C upstream_gene_variant 1.0 ethambutol
ubiA 4269364 p.Tyr157Phe missense_variant 1.0 ethambutol
ubiA 4269367 p.Ala156Gly missense_variant 1.0 ethambutol
aftB 4269555 c.-719C>G upstream_gene_variant 1.0 ethambutol
aftB 4269561 c.-725G>C upstream_gene_variant 1.0 ethambutol
aftB 4269564 c.-728G>T upstream_gene_variant 1.0 ethambutol
aftB 4269573 c.-737A>G upstream_gene_variant 1.0 ethambutol
aftB 4269594 c.-758A>C upstream_gene_variant 1.0 ethambutol
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
aftB 4269612 c.-776T>C upstream_gene_variant 1.0 ethambutol
aftB 4269621 c.-785C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269627 p.Val69Thr missense_variant 1.0 ethambutol
ubiA 4269632 p.Ala68Ser missense_variant 0.93 ethambutol
aftB 4269639 c.-803C>G upstream_gene_variant 1.0 ethambutol
ubiA 4269647 p.Ser63Cys missense_variant 1.0 ethambutol
aftB 4269660 c.-824C>T upstream_gene_variant 1.0 ethambutol
ubiA 4269665 p.Met57Val missense_variant 1.0 ethambutol
aftB 4269666 c.-830G>C upstream_gene_variant 1.0 ethambutol
ubiA 4269676 p.Ser53Thr missense_variant 1.0 ethambutol
ubiA 4269678 c.154_156delCTCinsTG frameshift_variant&synonymous_variant 1.0 ethambutol
ubiA 4269688 p.Val49Ala missense_variant 0.93 ethambutol Uncertain significance