TB-Profiler result

Run: ERR9786611
Summary

Run ID: ERR9786611

Sample name:

Date: 2024-04-15T07:21:40.698066

Number of reads: 1761519

Percentage reads mapped: 57.43

Median coverage: 73.0

Strain: lineage4.1.3

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1.3 Euro-American None 0.96
lineage4.1 Euro-American None 0.91
La1.2.BCG M.bovis None 0.14
lineage6.2.3 West-Africa 2 RD702 0.1
La1.7.1 M.bovis None 0.1
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid inhA c.-154G>A Assoc w R Alias fabG1_p.Leu203Leu. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
katG p.Ser315Thr Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
gid p.Leu79Ser Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.172_174delAGTinsGC Assoc w R
c.238_240delGCGinsTC Assoc w R
c.319_321delCACinsGA Assoc w R
c.376_378delCCTinsGG Assoc w R
kanamycin
cycloserine
ethionamide inhA c.-154G>A Assoc w R - Interim Alias fabG1_p.Leu203Leu
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.718_720delGAGinsAA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.604_606delTCGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 0.44 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.49 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 0.45 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491500 c.718_720delGAGinsAA frameshift_variant&missense_variant 0.22 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303534 c.604_606delTCGinsGC frameshift_variant&missense_variant 0.3 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGG frameshift_variant&missense_variant 0.33 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance Mutation from literature
inhA 1674048 c.-154G>A upstream_gene_variant 0.66 isoniazid Assoc w R Alias fabG1_p.Leu203Leu. Low-level resistance (multiple, genetically linked low-level resistance mutations are additive and confer high-level resistance)
ethionamide Assoc w R - Interim Alias fabG1_p.Leu203Leu
tlyA 1918111 c.172_174delAGTinsGC frameshift_variant&missense_variant 0.29 capreomycin Assoc w R
tlyA 1918177 c.238_240delGCGinsTC frameshift_variant&missense_variant 0.31 capreomycin Assoc w R
tlyA 1918258 c.319_321delCACinsGA frameshift_variant&missense_variant 0.35 capreomycin Assoc w R
tlyA 1918315 c.376_378delCCTinsGG frameshift_variant&missense_variant 0.28 capreomycin Assoc w R
katG 2155168 p.Ser315Thr missense_variant 0.97 isoniazid Assoc w R High-level resistance
embB 4247448 p.His312Arg missense_variant 0.38 ethambutol Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.44 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.48 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.45 ethambutol Mutation from literature
gid 4407967 p.Leu79Ser missense_variant 1.0 streptomycin Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 558 c.558G>C synonymous_variant 0.24 isoniazid
dnaA 561 c.561C>T synonymous_variant 0.24 isoniazid
dnaA 567 c.567C>G synonymous_variant 0.26 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.27 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.28 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 0.28 isoniazid
dnaA 588 c.588A>C synonymous_variant 0.28 isoniazid
dnaA 591 c.591C>G synonymous_variant 0.29 isoniazid
dnaA 597 c.597C>G synonymous_variant 0.32 isoniazid Not assoc w R - Interim
dnaA 600 c.600T>A synonymous_variant 0.3 isoniazid
dnaA 612 c.612G>C synonymous_variant 0.35 isoniazid
dnaA 627 c.627G>A synonymous_variant 0.37 isoniazid
dnaA 645 c.645A>C synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 649 c.649C>T synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.41 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.44 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.41 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.4 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>C synonymous_variant 0.4 isoniazid
dnaA 693 c.693A>G synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.44 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.44 isoniazid
dnaA 720 c.720G>A synonymous_variant 0.44 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.47 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.46 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.47 isoniazid
dnaA 768 c.768C>G synonymous_variant 0.47 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.47 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.49 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.46 isoniazid Uncertain significance
dnaA 813 c.813C>T synonymous_variant 0.48 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.46 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.45 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.44 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.44 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.44 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.44 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.44 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.34 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.34 isoniazid
dnaA 882 c.882C>T synonymous_variant 0.35 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.36 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.41 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.44 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.46 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.47 isoniazid Not assoc w R - Interim
dnaA 942 c.942C>G synonymous_variant 0.42 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.41 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.39 isoniazid
dnaA 960 c.960C>A synonymous_variant 0.36 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.36 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.36 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.38 isoniazid
dnaA 975 c.975G>T synonymous_variant 0.37 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.37 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.35 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.35 isoniazid
dnaA 999 c.999C>G synonymous_variant 0.35 isoniazid
dnaA 1003 c.1003C>T synonymous_variant 0.34 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.33 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.33 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.33 isoniazid
dnaA 1038 c.1038A>T synonymous_variant 0.36 isoniazid
dnaA 1041 c.1041G>A synonymous_variant 0.36 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.35 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.37 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.39 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.4 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.39 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.39 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.38 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.39 isoniazid
dnaA 1137 c.1137C>G synonymous_variant 0.39 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 0.38 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.34 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.34 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.37 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 0.37 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.37 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.39 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 0.4 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.4 isoniazid
dnaA 1197 c.1197T>C synonymous_variant 0.39 isoniazid Not assoc w R - Interim
dnaA 1204 c.1204C>T synonymous_variant 0.4 isoniazid
dnaA 1218 c.1218C>G synonymous_variant 0.37 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.37 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.42 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 0.42 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.44 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.46 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.44 isoniazid
dnaA 1284 c.1284C>G synonymous_variant 0.43 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.43 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.42 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 0.42 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 1311 c.1311C>G synonymous_variant 0.42 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.42 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.41 isoniazid
dnaA 1320 c.1320G>C synonymous_variant 0.41 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 0.41 isoniazid Not assoc w R - Interim
dnaA 1332 c.1332A>C synonymous_variant 0.42 isoniazid Not assoc w R - Interim
dnaA 1338 c.1338T>C synonymous_variant 0.41 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.42 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.38 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.38 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.35 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.33 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.32 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.33 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.33 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.33 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.32 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.33 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.33 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 0.26 isoniazid
dnaA 1461 c.1461C>G synonymous_variant 0.24 isoniazid
dnaA 1470 c.1470C>T synonymous_variant 0.23 isoniazid
gyrB 6238 c.999G>A synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.39 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6289 c.1050C>T synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 6304 c.-998C>G upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.29 levofloxacin
moxifloxacin
gyrA 6418 c.-884C>G upstream_gene_variant 0.28 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 6475 c.-827C>G upstream_gene_variant 0.22 levofloxacin
moxifloxacin
gyrA 6490 c.-812T>G upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.24 levofloxacin
moxifloxacin
gyrA 6502 c.-800T>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 0.2 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6565 c.-737G>C upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.27 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 0.27 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.38 levofloxacin Uncertain significance
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrB 6763 c.1524G>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6775 c.1536G>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.43 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.42 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6865 c.-437G>A upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642_1644delTTGinsCC frameshift_variant&missense_variant 0.4 levofloxacin Uncertain significance
moxifloxacin
gyrA 6889 c.-413G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6898 c.-404G>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6901 c.-401G>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6904 c.-398C>G upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6967 c.-335T>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.46 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7010 c.-292C>T upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.48 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.45 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>C upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 7093 c.-209T>G upstream_gene_variant 0.38 levofloxacin
moxifloxacin
gyrA 7099 c.-203G>A upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrB 7124 c.1885_1887delTCGinsAC frameshift_variant&missense_variant 0.34 levofloxacin Uncertain significance
moxifloxacin
gyrA 7129 c.-173T>C upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.33 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.35 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7216 c.1977G>C synonymous_variant 0.25 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7228 c.-74C>T upstream_gene_variant 0.23 levofloxacin
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7246 c.2007T>C synonymous_variant 0.23 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>C upstream_gene_variant 0.21 levofloxacin
moxifloxacin
gyrB 7256 c.2017_2019delCTGinsTA frameshift_variant&stop_gained 0.21 levofloxacin Uncertain significance
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.23 levofloxacin
moxifloxacin
gyrA 7347 c.46_48delGAAinsCG frameshift_variant&missense_variant 0.29 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.54 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7532 c.231T>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7562 c.261C>T synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7571 c.270G>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 0.99 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7625 c.324G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCC frameshift_variant&missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7697 c.396C>A synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCC frameshift_variant&missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7725 c.424C>T synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 0.31 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.21 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8135 c.834C>G synonymous_variant 0.22 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8198 c.897T>C synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 8276 c.975G>A synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8330 c.1029C>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8337 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.4 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8367 c.1066C>T synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.38 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.37 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8400 c.1099_1101delGACinsAT frameshift_variant&missense_variant 0.38 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8465 c.1164C>G synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 8472 c.1171C>T synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>A synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8520 c.1219C>T synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8528 c.1227G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8553 c.1252C>A synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 c.1287G>A synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8708 c.1407G>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.49 levofloxacin
moxifloxacin
gyrA 8740 p.Arg480His missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8750 c.1449C>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Ser missense_variant 0.49 levofloxacin
moxifloxacin
gyrA 8762 c.1461G>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.53 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8780 p.Asp493Glu missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8807 c.1506C>T synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8816 c.1515C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8818 p.Ser506Asn missense_variant 0.6 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8891 c.1590G>A synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8933 c.1632G>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.47 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>A synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.54 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.51 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>G synonymous_variant 0.49 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.42 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 0.39 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>A synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.45 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9153 p.Thr618Glu missense_variant 0.42 levofloxacin
moxifloxacin
gyrA 9158 c.1857C>T synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.42 levofloxacin
moxifloxacin
gyrA 9218 c.1917C>T synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9227 c.1926C>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.31 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 c.2007C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9312 c.2011C>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9317 c.2016G>T synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.32 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.32 levofloxacin
moxifloxacin
gyrA 9365 c.2064G>A synonymous_variant 0.25 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.23 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.22 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.21 levofloxacin
moxifloxacin
gyrA 9557 c.2256G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13897 c.-339C>T upstream_gene_variant 0.18 isoniazid
fgd1 490827 c.45C>T synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 0.29 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>T synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fgd1 490868 p.Ala29Gly missense_variant 0.3 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>A synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fgd1 490896 c.114C>T synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 0.39 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 490977 c.195C>G synonymous_variant 0.41 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Thr missense_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fgd1 491001 c.219G>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491063 p.Gly94Ala missense_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fgd1 491100 c.318C>T synonymous_variant 0.52 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491106 c.324T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491130 c.348C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>A synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491173 c.391C>A synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 0.4 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fgd1 491292 c.510G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 0.44 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491302 p.Ile174Val missense_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 491313 c.531C>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fgd1 491319 c.537G>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fgd1 491337 c.555C>G synonymous_variant 0.39 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491340 c.558C>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.39 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fgd1 491487 c.705C>T synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491512 p.Asn244Asp missense_variant 0.22 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fgd1 491535 c.753G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.26 clofazimine
pretomanid
delamanid
fgd1 491553 c.771G>A synonymous_variant 0.25 clofazimine
pretomanid
delamanid
mshA 575022 c.-326C>T upstream_gene_variant 0.23 ethionamide
isoniazid
mshA 575034 c.-314T>A upstream_gene_variant 0.21 ethionamide
isoniazid
mshA 575623 c.276C>G synonymous_variant 0.25 ethionamide
isoniazid
mshA 575629 c.282A>G synonymous_variant 0.24 ethionamide
isoniazid
mshA 575632 c.285G>C synonymous_variant 0.24 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.25 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 0.25 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 0.25 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.26 ethionamide
isoniazid
mshA 575649 p.Val101Ala missense_variant 0.26 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.27 ethionamide
isoniazid
mshA 575662 c.315C>G synonymous_variant 0.27 ethionamide
isoniazid
mshA 575665 c.318G>A synonymous_variant 0.29 ethionamide
isoniazid
mshA 575674 c.327G>C synonymous_variant 0.32 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.36 ethionamide
isoniazid Not assoc w R - Interim
mshA 575701 c.354G>A synonymous_variant 0.36 ethionamide
isoniazid
mshA 575704 c.357T>G synonymous_variant 0.36 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.35 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.4 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.38 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.4 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.41 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.4 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 0.37 ethionamide
isoniazid
mshA 575755 c.408G>A synonymous_variant 0.38 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.39 ethionamide
isoniazid
mshA 575770 c.423G>A synonymous_variant 0.4 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.4 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.43 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.42 ethionamide
isoniazid
mshA 575809 c.462C>T synonymous_variant 0.44 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.44 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.43 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.42 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.41 ethionamide
isoniazid
mshA 575833 c.486C>G synonymous_variant 0.42 ethionamide
isoniazid
mshA 575845 c.498C>T synonymous_variant 0.44 ethionamide
isoniazid Not assoc w R - Interim
mshA 575884 c.537G>C synonymous_variant 0.45 ethionamide
isoniazid
mshA 575887 c.540G>C synonymous_variant 0.43 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.42 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.41 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.39 ethionamide
isoniazid
mshA 575917 p.Asp190Glu missense_variant 0.38 ethionamide
isoniazid
mshA 575920 c.573C>G synonymous_variant 0.39 ethionamide
isoniazid
mshA 575924 p.Gly193Ser missense_variant 0.38 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.37 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.35 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.31 ethionamide
isoniazid Not assoc w R - Interim
mshA 575977 c.630G>C synonymous_variant 0.27 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.26 ethionamide
isoniazid
mshA 575984 c.637T>C synonymous_variant 0.26 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 619528 c.-363C>G upstream_gene_variant 0.3 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 619535 c.-356_-354delCAAinsGCG upstream_gene_variant 0.29 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 0.3 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>G upstream_gene_variant 0.32 capreomycin
amikacin
kanamycin
ccsA 619561 c.-330G>C upstream_gene_variant 0.3 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.3 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.31 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.31 capreomycin
amikacin
kanamycin
ccsA 619584 c.-307A>T upstream_gene_variant 0.32 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.31 capreomycin
amikacin
kanamycin
ccsA 619609 c.-282G>T upstream_gene_variant 0.32 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257T>A upstream_gene_variant 0.28 capreomycin
amikacin
kanamycin
ccsA 619645 c.-246G>C upstream_gene_variant 0.31 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.3 capreomycin
amikacin
kanamycin
ccsA 619668 c.-223_-222delCGinsGC upstream_gene_variant 0.24 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>T upstream_gene_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 619676 c.-215C>G upstream_gene_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>T synonymous_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620310 c.420C>T synonymous_variant 0.23 capreomycin
amikacin
kanamycin
ccsA 620319 c.429C>G synonymous_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.24 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.28 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.28 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.27 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.26 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.25 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.21 capreomycin
amikacin
kanamycin
ccsA 620424 c.534G>C synonymous_variant 0.24 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.25 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 0.22 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.23 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.23 capreomycin
amikacin
kanamycin
Rv0565c 656112 c.1359C>G synonymous_variant 0.23 ethionamide
Rv0565c 656129 p.Tyr448His missense_variant 0.23 ethionamide
Rv0565c 656131 p.Pro447Val missense_variant 0.23 ethionamide
Rv0565c 656135 p.Ala446Ser missense_variant 0.23 ethionamide
Rv0565c 656136 c.1335G>C synonymous_variant 0.23 ethionamide
Rv0565c 656140 p.Lys444Leu missense_variant 0.23 ethionamide
Rv0565c 656145 c.1326T>C synonymous_variant 0.24 ethionamide
Rv0565c 656154 c.1315_1317delCAGinsAC frameshift_variant&missense_variant 0.25 ethionamide Uncertain significance
Rv0565c 656157 c.1314T>C synonymous_variant 0.23 ethionamide
Rv0565c 656166 c.1305C>G synonymous_variant 0.25 ethionamide
Rv0565c 656172 c.1299A>G synonymous_variant 0.28 ethionamide
Rv0565c 656179 p.Asp431Thr missense_variant 0.28 ethionamide
Rv0565c 656192 p.Asp427Asn missense_variant 0.31 ethionamide Uncertain significance
Rv0565c 656196 p.Leu425Arg missense_variant 0.31 ethionamide
Rv0565c 656219 p.His418Tyr missense_variant 0.32 ethionamide
Rv0565c 656220 c.1251A>C synonymous_variant 0.33 ethionamide
Rv0565c 656223 c.1248T>C synonymous_variant 0.33 ethionamide Not assoc w R - Interim
Rv0565c 656226 c.1243_1245delGCCinsTT frameshift_variant&missense_variant 0.33 ethionamide Uncertain significance
Rv0565c 656238 p.Ala411Glu missense_variant 0.34 ethionamide
Rv0565c 656243 p.Leu410Met missense_variant 0.35 ethionamide
Rv0565c 656244 c.1227A>C synonymous_variant 0.35 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.38 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.38 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.37 ethionamide
Rv0565c 656289 c.1182C>G synonymous_variant 0.33 ethionamide
Rv0565c 656298 c.1173G>C synonymous_variant 0.35 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.28 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 0.25 ethionamide
Rv0565c 656358 c.1113T>C synonymous_variant 0.26 ethionamide Not assoc w R - Interim
Rv0565c 656361 c.1110C>G synonymous_variant 0.26 ethionamide
Rv0565c 656364 c.1107T>C synonymous_variant 0.26 ethionamide
Rv0565c 656367 c.1101_1104delTCGGinsGC frameshift_variant&synonymous_variant 0.26 ethionamide Uncertain significance
Rv0565c 656371 p.Pro367His missense_variant 0.28 ethionamide
Rv0565c 656375 c.1095_1096insAA frameshift_variant 0.27 ethionamide Uncertain significance
Rv0565c 656383 p.Val363Asn missense_variant 0.26 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.31 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 0.32 ethionamide
Rv0565c 656412 c.1059T>G synonymous_variant 0.34 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.33 ethionamide
Rv0565c 656448 c.1021_1023delATTinsGC frameshift_variant&missense_variant 0.32 ethionamide Uncertain significance
Rv0565c 656454 c.1017G>C synonymous_variant 0.33 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 0.32 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 0.32 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 0.29 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 0.27 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 0.26 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.27 ethionamide
Rv0565c 656502 c.969C>T synonymous_variant 0.27 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.25 ethionamide Not assoc w R - Interim
Rv0565c 656535 c.936C>G synonymous_variant 0.22 ethionamide
Rv0565c 656539 p.Ser311Thr missense_variant 0.21 ethionamide
Rv0565c 657138 c.331_333delGCAinsTG frameshift_variant&missense_variant 0.26 ethionamide Uncertain significance
Rv0565c 657144 c.327T>G synonymous_variant 0.25 ethionamide
Rv0565c 657155 p.Asn106Asp missense_variant 0.27 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 0.26 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 0.29 ethionamide
Rv0565c 657187 p.His95Arg missense_variant 0.26 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 0.24 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.24 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.24 ethionamide
Rv0565c 657198 c.271_273delACCinsGG frameshift_variant&missense_variant 0.24 ethionamide Uncertain significance
Rv0565c 657201 c.270C>G synonymous_variant 0.24 ethionamide
Rv0565c 657216 p.His85Gln missense_variant 0.29 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.29 ethionamide
Rv0565c 657231 c.238_240delATCinsGG frameshift_variant&missense_variant 0.31 ethionamide Uncertain significance
Rv0565c 657237 c.234A>G synonymous_variant 0.37 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.36 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.35 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.36 ethionamide
Rv0565c 657267 c.202_204delTCGinsCC frameshift_variant&synonymous_variant 0.37 ethionamide Uncertain significance
Rv0565c 657300 c.171C>G synonymous_variant 0.42 ethionamide
Rv0565c 657303 c.168C>T synonymous_variant 0.41 ethionamide Not assoc w R - Interim
Rv0565c 657318 c.153T>C synonymous_variant 0.29 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.29 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.24 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.21 ethionamide Uncertain significance
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.21 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.21 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.29 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.26 ethionamide
Rv0565c 657678 c.-209_-208delAAinsTC upstream_gene_variant 0.25 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAC upstream_gene_variant 0.28 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.28 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.32 ethionamide
hadA 731682 c.-248C>G upstream_gene_variant 0.28 isoniazid
hadA 731687 c.-243_-242insCACAGATCTTTT upstream_gene_variant 0.28 isoniazid
hadA 731693 c.-237C>A upstream_gene_variant 0.28 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.27 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 0.26 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.26 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.26 isoniazid
hadA 731717 c.-213T>G upstream_gene_variant 0.28 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.28 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.31 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.31 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.27 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.27 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.23 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.24 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.24 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.25 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.26 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.32 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.37 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.41 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.54 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.58 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.58 isoniazid
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.3 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.4 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.38 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.42 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.43 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.43 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.43 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
nusG 734532 c.279A>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.49 rifampicin
nusG 734559 c.306T>C synonymous_variant 0.5 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.5 rifampicin
nusG 734596 c.343T>C synonymous_variant 0.44 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.47 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.43 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.33 rifampicin
nusG 734631 c.378G>C synonymous_variant 0.33 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.33 rifampicin
nusG 734637 c.384G>C synonymous_variant 0.33 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.31 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.28 rifampicin
nusG 734658 c.405A>G synonymous_variant 0.25 rifampicin Not assoc w R
nusG 734661 c.408A>G synonymous_variant 0.24 rifampicin Not assoc w R - Interim
nusG 734664 c.411T>G synonymous_variant 0.26 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.26 rifampicin
nusG 734676 c.423G>C synonymous_variant 0.25 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
nusG 734680 c.427_429delGCCinsAG frameshift_variant&missense_variant 0.24 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.29 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.27 rifampicin
nusG 734715 c.462G>C synonymous_variant 0.23 rifampicin
nusG 734719 p.Ser156Ala missense_variant 0.23 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.21 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.35 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.36 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.38 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.52 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.63 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.62 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.66 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.66 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.69 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.69 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.69 rifampicin
rpoB 760406 c.600G>C synonymous_variant 0.7 rifampicin
rpoB 760412 c.606C>G synonymous_variant 0.7 rifampicin
rpoB 760424 c.618C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.61 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.58 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.56 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.61 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.53 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>T synonymous_variant 0.44 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.31 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.27 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.27 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.24 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.24 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.23 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.24 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.22 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.22 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.23 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 0.26 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.47 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.56 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.63 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.6 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.63 rifampicin
rpoB 761213 c.1407G>C synonymous_variant 0.61 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761306 c.1500C>G synonymous_variant 0.57 rifampicin
rpoB 761312 c.1506G>C synonymous_variant 0.56 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.59 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.56 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.52 rifampicin
rpoB 761373 p.Val523His missense_variant 0.48 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.45 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.42 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.4 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.4 rifampicin
rpoB 761439 c.1633_1635delGACinsAG frameshift_variant&missense_variant 0.4 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.42 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.4 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.41 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.42 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 0.53 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.48 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.48 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.42 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.44 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.48 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.47 rifampicin
rpoB 761720 c.1914_1916delCGAinsGG frameshift_variant&synonymous_variant 0.39 rifampicin
rpoB 761727 p.Ser641Gly missense_variant 0.39 rifampicin
rpoB 761728 c.1923dupC frameshift_variant 0.39 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.4 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.43 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.43 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.44 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.42 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.44 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.42 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.35 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.33 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.35 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.31 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.33 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.35 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.36 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.38 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.4 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.38 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.37 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.37 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.37 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.5 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.59 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.56 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.51 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.51 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762206 c.2400C>G synonymous_variant 0.53 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 0.52 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.5 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.5 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.5 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.48 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.46 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.47 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.49 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.55 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.53 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.57 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 762419 c.-951C>G upstream_gene_variant 0.57 rifampicin
rpoC 762434 c.-936T>C upstream_gene_variant 0.6 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 762467 c.-903C>T upstream_gene_variant 0.53 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.41 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.44 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.43 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.42 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.38 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.36 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.36 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 0.33 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.21 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.26 rifampicin Not assoc w R - Interim
rpoB 762926 c.3120C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.53 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.6 rifampicin
rpoC 763025 c.-345C>T upstream_gene_variant 0.58 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.56 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.57 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763190 c.-180C>T upstream_gene_variant 0.53 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.47 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.47 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.48 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.51 rifampicin
rpoB 763227 c.3421C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 763238 c.3432T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 763253 c.-117G>C upstream_gene_variant 0.42 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.41 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.32 rifampicin
rpoC 763310 c.-60C>T upstream_gene_variant 0.25 rifampicin
rpoB 763316 c.3510T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 763319 c.-51T>C upstream_gene_variant 0.25 rifampicin
rpoC 763322 c.-48G>C upstream_gene_variant 0.24 rifampicin
rpoC 763325 c.-44_-37delAGCTGTCG upstream_gene_variant 0.26 rifampicin
rpoC 763338 c.-32delAinsCGTTTTCAG upstream_gene_variant 0.25 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.31 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 0.47 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.46 rifampicin
rpoC 763441 c.72C>T synonymous_variant 0.45 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.54 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.62 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.56 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.57 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.57 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.58 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.6 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.61 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.56 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.58 rifampicin
rpoC 763853 p.Val162Ile missense_variant 0.61 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.61 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.59 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.59 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.58 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.57 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.57 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.56 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763936 c.567C>G synonymous_variant 0.58 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.57 rifampicin
rpoC 763942 c.573C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763948 c.579G>A synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 763949 c.580C>A synonymous_variant 0.53 rifampicin
rpoC 763954 c.585C>G synonymous_variant 0.54 rifampicin
rpoC 763963 c.594C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 763987 c.618C>T synonymous_variant 0.51 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 0.48 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.49 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.5 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.5 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.52 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.51 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.52 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.53 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.51 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Ile missense_variant 0.5 rifampicin
rpoC 764112 p.Tyr248Phe missense_variant 0.5 rifampicin
rpoC 764116 c.747C>T synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.53 rifampicin
rpoC 764140 c.771C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764188 c.819A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.54 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.54 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764215 c.846A>G synonymous_variant 0.56 rifampicin
rpoC 764236 c.867G>A synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764248 c.879C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.54 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.49 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.49 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.5 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764338 c.969G>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.61 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.56 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.55 rifampicin
rpoC 764405 c.1036A>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.59 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.58 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.59 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.59 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.59 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764510 c.1141C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.58 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.57 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764581 c.1212T>C synonymous_variant 0.54 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.59 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>C synonymous_variant 0.52 rifampicin
rpoC 764651 c.1282_1284delTCGinsAGC synonymous_variant 0.52 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.57 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.56 rifampicin
rpoC 764932 c.1563C>A synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.54 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.51 rifampicin Not assoc w R
rpoC 765019 c.1650A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.48 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1685delTCinsAG synonymous_variant 0.48 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.43 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 0.42 rifampicin
rpoC 765150 p.Gly594Glu missense_variant 0.96 rifampicin Not assoc w R
rpoC 765292 c.1923G>C synonymous_variant 0.46 rifampicin
rpoC 765298 c.1929G>C synonymous_variant 0.45 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.47 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.45 rifampicin Uncertain significance
rpoC 765329 p.Ser654Gly missense_variant 0.46 rifampicin
rpoC 765346 c.1977C>G synonymous_variant 0.47 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.54 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.59 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.62 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.64 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.64 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.63 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.62 rifampicin
rpoC 765580 c.2211G>C synonymous_variant 0.61 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.6 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.6 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>T synonymous_variant 0.59 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.56 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.55 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.58 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.59 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.6 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.6 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.6 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.54 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.53 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.54 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.54 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.55 rifampicin
rpoC 766027 c.2658G>C synonymous_variant 0.56 rifampicin
rpoC 766030 c.2661C>G synonymous_variant 0.55 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.56 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.61 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.58 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.6 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.65 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.62 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 766174 p.Asn935Lys missense_variant 0.58 rifampicin
rpoC 766178 p.Ile937Val missense_variant 0.58 rifampicin
rpoC 766185 p.Glu939Ala missense_variant 0.52 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766192 c.2823T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 766193 c.2824_2826delCAAinsGG frameshift_variant&missense_variant 0.46 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 0.49 rifampicin
rpoC 766207 c.2838T>C synonymous_variant 0.48 rifampicin
rpoC 766216 c.2847T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 766219 p.Asp950Glu missense_variant 0.49 rifampicin
rpoC 766222 c.2853T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 766226 c.2857T>C synonymous_variant 0.49 rifampicin
rpoC 766231 c.2862T>G synonymous_variant 0.5 rifampicin
rpoC 766234 c.2865T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 766237 c.2868T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 766240 c.2871T>C synonymous_variant 0.48 rifampicin
rpoC 766243 c.2874C>G synonymous_variant 0.48 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 0.54 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.49 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.48 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.51 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.49 rifampicin
rpoC 766303 c.2934C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.56 rifampicin
rpoC 766327 c.2958C>A synonymous_variant 0.53 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.52 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.52 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.53 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.51 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.51 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.54 rifampicin
rpoC 766408 c.3039C>G synonymous_variant 0.55 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.56 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 0.65 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.69 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 0.72 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.66 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.64 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.7 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.7 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.65 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.66 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.72 rifampicin
rpoC 766549 c.3180G>T synonymous_variant 0.66 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.66 rifampicin
rpoC 766582 c.3213C>G synonymous_variant 0.65 rifampicin
rpoC 766583 c.3214_3216delGGTinsAC frameshift_variant&missense_variant 0.64 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.63 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.63 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.65 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.58 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.57 rifampicin
rpoC 766660 c.3291G>C synonymous_variant 0.56 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.5 rifampicin
rpoC 766673 p.Gly1102Asn missense_variant 0.49 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.51 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.51 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.56 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.57 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.6 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.61 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.6 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.61 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.61 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.67 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.64 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.62 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.62 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.57 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.6 rifampicin
rpoC 767158 c.3789T>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.54 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.45 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.32 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.29 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.28 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.29 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781421 c.-139C>A upstream_gene_variant 1.0 streptomycin Uncertain significance
rpsL 781571 c.12C>T synonymous_variant 0.22 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.33 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.33 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.33 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.41 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.43 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.53 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.49 streptomycin
rpsL 781700 c.141G>C synonymous_variant 0.47 streptomycin
rpsL 781703 c.144G>T synonymous_variant 0.46 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.47 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.48 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.5 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.54 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.53 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.54 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.54 streptomycin
rpsL 781772 c.213C>A synonymous_variant 0.52 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.59 streptomycin
rpsL 781811 c.252C>T synonymous_variant 0.6 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.57 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.56 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.58 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.56 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.57 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.57 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.56 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.59 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.56 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.57 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.57 streptomycin Uncertain significance
rplC 800537 c.-272C>T upstream_gene_variant 0.27 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.28 linezolid
rplC 800546 c.-263T>G upstream_gene_variant 0.28 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.29 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.29 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.33 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.35 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.33 linezolid
rplC 800648 c.-161A>T upstream_gene_variant 0.37 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.37 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.46 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.45 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.45 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.45 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.45 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.48 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.51 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.45 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.44 linezolid
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.45 linezolid
rplC 800814 c.6A>G synonymous_variant 0.45 linezolid
rplC 800817 c.9A>T synonymous_variant 0.44 linezolid
rplC 800844 c.36T>C synonymous_variant 0.47 linezolid
rplC 800865 c.57A>G synonymous_variant 0.47 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.47 linezolid
rplC 800874 c.66A>G synonymous_variant 0.47 linezolid
rplC 800875 c.67_69delGTAinsAT frameshift_variant&missense_variant 0.47 linezolid
rplC 800880 c.72A>G synonymous_variant 0.45 linezolid
rplC 800889 c.81C>G synonymous_variant 0.46 linezolid
rplC 800892 c.84G>C synonymous_variant 0.46 linezolid
rplC 800907 c.99C>G synonymous_variant 0.47 linezolid
rplC 800916 c.108A>G synonymous_variant 0.45 linezolid
rplC 800934 c.126C>G synonymous_variant 0.41 linezolid
rplC 800937 c.129A>G synonymous_variant 0.39 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.39 linezolid
rplC 800946 c.138T>C synonymous_variant 0.4 linezolid
rplC 800949 c.141T>C synonymous_variant 0.4 linezolid
rplC 800967 c.159C>G synonymous_variant 0.4 linezolid
rplC 800970 c.162T>C synonymous_variant 0.4 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.44 linezolid
rplC 800985 c.177A>G synonymous_variant 0.44 linezolid
rplC 801004 p.Leu66Val missense_variant 0.43 linezolid
rplC 801009 c.201A>C synonymous_variant 0.43 linezolid
rplC 801019 c.211_213delACCinsGG frameshift_variant&missense_variant 0.46 linezolid
rplC 801027 c.219C>G synonymous_variant 0.47 linezolid
rplC 801039 c.231A>G synonymous_variant 0.42 linezolid
rplC 801045 c.237A>G synonymous_variant 0.41 linezolid
rplC 801047 p.Tyr80Phe missense_variant 0.39 linezolid
rplC 801049 c.241C>T synonymous_variant 0.39 linezolid
rplC 801054 c.246G>C synonymous_variant 0.41 linezolid
rplC 801070 p.Asp88Asn missense_variant 0.41 linezolid
rplC 801073 p.Ser89Pro missense_variant 0.42 linezolid
rplC 801078 c.270T>C synonymous_variant 0.43 linezolid
rplC 801081 c.273C>G synonymous_variant 0.43 linezolid Not assoc w R - Interim
rplC 801085 c.277_279delACCinsGG frameshift_variant&missense_variant 0.42 linezolid
rplC 801090 c.282G>A synonymous_variant 0.38 linezolid
rplC 801099 c.291T>C synonymous_variant 0.41 linezolid
rplC 801102 c.294G>C synonymous_variant 0.41 linezolid
rplC 801105 c.297A>G synonymous_variant 0.41 linezolid
rplC 801109 c.301T>C synonymous_variant 0.41 linezolid Not assoc w R - Interim
rplC 801114 c.306C>G synonymous_variant 0.41 linezolid
rplC 801117 c.309G>C synonymous_variant 0.41 linezolid
rplC 801127 p.Ala107Thr missense_variant 0.44 linezolid
rplC 801132 c.324T>C synonymous_variant 0.47 linezolid
rplC 801147 c.339T>C synonymous_variant 0.47 linezolid
rplC 801150 c.342G>C synonymous_variant 0.48 linezolid
rplC 801153 c.345G>C synonymous_variant 0.48 linezolid
rplC 801156 c.348T>A synonymous_variant 0.48 linezolid
rplC 801168 c.360C>G synonymous_variant 0.53 linezolid
rplC 801171 c.363A>G synonymous_variant 0.51 linezolid
rplC 801174 c.366T>C synonymous_variant 0.54 linezolid
rplC 801195 c.387G>C synonymous_variant 0.49 linezolid
rplC 801207 c.399C>T synonymous_variant 0.45 linezolid
rplC 801246 c.438C>T synonymous_variant 0.39 linezolid
rplC 801249 c.441T>C synonymous_variant 0.39 linezolid
rplC 801255 c.447C>T synonymous_variant 0.37 linezolid
rplC 801264 c.456C>T synonymous_variant 0.36 linezolid
rplC 801267 c.459A>T synonymous_variant 0.36 linezolid
rplC 801270 c.462T>C synonymous_variant 0.36 linezolid
rplC 801276 c.468G>C synonymous_variant 0.36 linezolid
rplC 801279 c.471G>C synonymous_variant 0.38 linezolid
rplC 801282 c.474G>C synonymous_variant 0.38 linezolid
rplC 801285 c.477G>C synonymous_variant 0.38 linezolid
rplC 801300 c.492C>G synonymous_variant 0.38 linezolid
rplC 801309 c.501C>G synonymous_variant 0.38 linezolid
rplC 801312 c.504G>C synonymous_variant 0.38 linezolid
rplC 801321 c.513C>T synonymous_variant 0.43 linezolid Not assoc w R - Interim
rplC 801324 c.516T>C synonymous_variant 0.42 linezolid
rplC 801339 c.531T>C synonymous_variant 0.44 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.44 linezolid
rplC 801348 c.540T>G synonymous_variant 0.44 linezolid
rplC 801357 c.549T>C synonymous_variant 0.46 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.49 linezolid
rplC 801402 c.594T>C synonymous_variant 0.51 linezolid
rplC 801405 c.597T>C synonymous_variant 0.51 linezolid
rplC 801423 c.615G>C synonymous_variant 0.55 linezolid
rplC 801426 c.618C>G synonymous_variant 0.54 linezolid
rplC 801427 p.Met207Val missense_variant 0.55 linezolid
rplC 801438 c.630T>C synonymous_variant 0.56 linezolid
rplC 801442 p.Ile212Val missense_variant 0.57 linezolid
fbiC 1303497 c.567G>A synonymous_variant 0.21 clofazimine
pretomanid
delamanid
fbiC 1303501 c.571C>T synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.27 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1303530 c.600G>A synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>C synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303650 c.720G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303654 c.724C>T synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1303663 c.733C>T synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1303671 c.741C>T synonymous_variant 0.4 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1303728 c.798G>A synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1303749 c.819G>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 0.33 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1303761 c.831T>C synonymous_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1303797 c.867A>G synonymous_variant 0.36 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303836 c.906G>C synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303845 c.915C>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1303846 p.Phe306Val missense_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303884 c.954T>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1303914 c.984C>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1303920 c.990C>T synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1303944 c.1014G>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303947 c.1017T>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303948 p.Gly340Arg missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303953 p.Asp341Glu missense_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303956 c.1026A>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303961 p.Arg344Leu missense_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>A synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1303998 c.1068T>G synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304034 c.1104A>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304046 c.1116C>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304049 c.1119T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304050 c.1120T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304058 c.1128G>A synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304059 c.1129C>T synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304064 c.1134G>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304067 c.1137G>C synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>T synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304091 p.Asp387Glu missense_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304097 c.1167G>C synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1304106 c.1176G>C synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.3 clofazimine
pretomanid
delamanid
fbiC 1304132 p.Ala401Gly missense_variant 0.26 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.28 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.24 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>T synonymous_variant 0.73 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304613 c.1683T>C synonymous_variant 0.29 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.35 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.33 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.34 clofazimine
pretomanid
delamanid
fbiC 1304691 c.1761G>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1304711 p.Ala594Glu missense_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.42 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1304739 c.1809C>T synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>T synonymous_variant 0.49 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304862 c.1932G>A synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304869 c.1939C>T synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304883 p.Glu651Asp missense_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304891 p.Ile654Thr missense_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304907 c.1977C>G synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1304983 c.2053C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.49 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>G synonymous_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1305030 c.2100G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.41 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1305114 c.2184T>C synonymous_variant 0.25 clofazimine
pretomanid
delamanid
fbiC 1305117 c.2187T>C synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1305126 c.2196T>C synonymous_variant 0.23 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.23 clofazimine
pretomanid
delamanid
fbiC 1305331 p.Glu801Lys missense_variant 0.22 clofazimine
pretomanid
delamanid
sigE 1364709 c.297T>C synonymous_variant 0.24 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.26 pyrazinamide
sigE 1364718 c.306C>T synonymous_variant 0.27 pyrazinamide
sigE 1364727 c.315C>T synonymous_variant 0.27 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.3 pyrazinamide
sigE 1364748 c.336G>C synonymous_variant 0.31 pyrazinamide
sigE 1364751 c.339C>G synonymous_variant 0.31 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.3 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.29 pyrazinamide
sigE 1364772 c.360G>C synonymous_variant 0.29 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 0.29 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.28 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.27 pyrazinamide
sigE 1364793 c.381C>T synonymous_variant 0.29 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.33 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.33 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.33 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.32 pyrazinamide
sigE 1364839 c.427_429delTTGinsCC frameshift_variant&missense_variant 0.31 pyrazinamide Uncertain significance
sigE 1364847 c.435G>C synonymous_variant 0.35 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.35 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 0.34 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.34 pyrazinamide
sigE 1364868 c.456T>G synonymous_variant 0.34 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.31 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 0.3 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.27 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.24 pyrazinamide
sigE 1364943 c.531C>T synonymous_variant 0.23 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.25 pyrazinamide
sigE 1365057 c.645C>T synonymous_variant 0.25 pyrazinamide
sigE 1365063 c.651A>C synonymous_variant 0.24 pyrazinamide
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.21 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.31 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.3 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.4 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472044 n.199G>T non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>A non_coding_transcript_exon_variant 0.43 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.53 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.46 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.54 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.31 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.43 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.49 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.42 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.66 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.59 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475761 n.2104_2106delCGCinsGT non_coding_transcript_exon_variant 0.51 capreomycin
linezolid
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.49 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.49 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476031 n.2374C>T non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.31 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476048 n.2391G>A non_coding_transcript_exon_variant 0.32 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.35 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.43 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.44 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.4 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.3 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.3 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.26 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.21 capreomycin
linezolid
inhA 1673523 c.-679G>T upstream_gene_variant 0.3 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.32 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.33 ethionamide
isoniazid
inhA 1673568 c.-634C>G upstream_gene_variant 0.37 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.38 ethionamide
isoniazid
inhA 1673580 c.-622T>G upstream_gene_variant 0.37 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.38 ethionamide
isoniazid
inhA 1673591 c.-611C>T upstream_gene_variant 0.38 ethionamide
isoniazid Uncertain significance
inhA 1673595 c.-607A>C upstream_gene_variant 0.37 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.37 ethionamide
isoniazid
inhA 1673602 c.-600C>T upstream_gene_variant 0.39 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.39 ethionamide
isoniazid
fabG1 1673615 p.Glu59Val missense_variant 0.39 ethionamide
isoniazid
inhA 1673619 c.-583T>C upstream_gene_variant 0.38 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.41 ethionamide
isoniazid
fabG1 1673637 p.Asp66Glu missense_variant 0.42 ethionamide
isoniazid
fabG1 1673641 p.Val68Ile missense_variant 0.44 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.48 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.48 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.48 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.49 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.53 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.54 ethionamide
isoniazid
fabG1 1673710 p.Leu91Ile missense_variant 0.57 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.57 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.5 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.46 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.46 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.47 ethionamide
isoniazid
fabG1 1673797 c.358_360delGCTinsAC frameshift_variant&missense_variant 0.45 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.45 ethionamide
isoniazid
inhA 1673805 c.-397G>C upstream_gene_variant 0.45 ethionamide
isoniazid
inhA 1673808 c.-394A>C upstream_gene_variant 0.45 ethionamide
isoniazid
fabG1 1673809 p.Ser124Ala missense_variant 0.44 ethionamide
isoniazid
fabG1 1673823 c.385_388delCGCA frameshift_variant 0.48 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 0.46 ethionamide
isoniazid
fabG1 1673832 c.393_394insGCGG frameshift_variant 0.46 ethionamide
isoniazid
inhA 1673841 c.-361A>C upstream_gene_variant 0.43 ethionamide
isoniazid
fabG1 1673844 p.Met135Ile missense_variant 0.43 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 0.43 ethionamide
isoniazid
fabG1 1673849 p.Phe137Tyr missense_variant 0.44 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 0.43 ethionamide
isoniazid
inhA 1673856 c.-346T>C upstream_gene_variant 0.43 ethionamide
isoniazid
fabG1 1673890 p.Ala151Ser missense_variant 0.47 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.46 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.38 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.37 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.34 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.34 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.41 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.41 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.41 ethionamide
isoniazid
inhA 1673985 c.-217C>G upstream_gene_variant 0.39 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.41 ethionamide
isoniazid
inhA 1674015 c.-187C>T upstream_gene_variant 0.37 ethionamide
isoniazid Uncertain significance
inhA 1674018 c.-184G>C upstream_gene_variant 0.36 ethionamide
isoniazid
inhA 1674021 c.-181G>C upstream_gene_variant 0.35 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.35 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.34 ethionamide
isoniazid
fabG1 1674037 p.Gln200Ala missense_variant 0.36 ethionamide
isoniazid
inhA 1674042 c.-160G>T upstream_gene_variant 0.35 ethionamide
isoniazid
fabG1 1674049 c.610_612delCAAinsGC frameshift_variant&missense_variant 0.34 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.34 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.38 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 0.37 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.36 ethionamide
isoniazid
inhA 1674105 c.-97C>T upstream_gene_variant 0.31 ethionamide
isoniazid
inhA 1674114 c.-88T>A upstream_gene_variant 0.28 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.27 ethionamide
isoniazid
inhA 1674126 c.-76G>C upstream_gene_variant 0.26 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.23 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 0.23 ethionamide
isoniazid
inhA 1674141 c.-61T>C upstream_gene_variant 0.24 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.31 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.34 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.33 ethionamide
isoniazid
inhA 1674504 c.303C>G synonymous_variant 0.29 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.28 ethionamide
isoniazid
inhA 1674537 c.336C>G synonymous_variant 0.26 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.26 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.28 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.27 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.25 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.23 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.23 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.28 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674672 c.471C>G synonymous_variant 0.42 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 0.49 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674738 c.537C>G synonymous_variant 0.57 ethionamide
isoniazid
inhA 1674741 c.540C>T synonymous_variant 0.55 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674746 p.Tyr182Phe missense_variant 0.55 ethionamide
isoniazid
inhA 1674750 c.549T>C synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674753 c.552G>C synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.57 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.59 ethionamide
isoniazid
inhA 1674774 c.573A>G synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674789 c.588G>C synonymous_variant 0.57 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 0.61 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674822 c.621C>G synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.58 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.53 ethionamide
isoniazid
inhA 1674864 c.663C>T synonymous_variant 0.43 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674870 c.669T>C synonymous_variant 0.45 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.42 ethionamide
isoniazid
inhA 1674888 c.687C>G synonymous_variant 0.37 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 0.34 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.34 ethionamide
isoniazid
rpsA 1833515 c.-27_-24delCAACinsAAA upstream_gene_variant 0.24 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.33 pyrazinamide
rpsA 1833554 p.Thr5Ala missense_variant 0.39 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.37 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.39 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.33 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.47 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.46 pyrazinamide
rpsA 1833721 c.180A>G synonymous_variant 0.47 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.46 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.5 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.5 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.5 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.5 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.5 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.51 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.46 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.42 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.43 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.47 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.48 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.53 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 0.53 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.54 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.53 pyrazinamide
rpsA 1833971 c.430C>T synonymous_variant 0.49 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.5 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.49 pyrazinamide
rpsA 1834081 c.540C>T synonymous_variant 0.43 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.37 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.37 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.38 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 0.38 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.38 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.37 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.35 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.36 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.36 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.36 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.36 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.36 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.36 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.41 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834210 c.669C>T synonymous_variant 0.49 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.48 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
rpsA 1834262 c.721_723delTCGinsAGC synonymous_variant 0.49 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 0.52 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.51 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.54 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.55 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.53 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.54 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.55 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.56 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.59 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.63 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.65 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.63 pyrazinamide
rpsA 1834618 c.1077G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.57 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.58 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.61 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.57 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834733 p.Ala398Ser missense_variant 0.49 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.48 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.48 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 0.47 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.46 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.43 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.42 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.43 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.55 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.53 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.54 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.53 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.43 linezolid
tsnR 1853423 c.-183C>T upstream_gene_variant 0.4 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.37 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.37 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.35 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.29 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.29 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.28 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.27 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 0.26 linezolid
tsnR 1853484 c.-122_-120delAGCinsGCG upstream_gene_variant 0.26 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.27 linezolid
tsnR 1853498 c.-108G>C upstream_gene_variant 0.27 linezolid
tsnR 1853517 c.-89G>A upstream_gene_variant 0.21 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917990 c.51G>C synonymous_variant 0.21 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.21 capreomycin Not assoc w R - Interim
tlyA 1918036 p.Arg33Ser missense_variant 0.24 capreomycin
tlyA 1918048 p.Leu37Met missense_variant 0.25 capreomycin
tlyA 1918053 c.114G>C synonymous_variant 0.24 capreomycin
tlyA 1918057 p.Val40Arg missense_variant 0.23 capreomycin
tlyA 1918065 c.126G>C synonymous_variant 0.24 capreomycin
tlyA 1918067 p.Ala43Gly missense_variant 0.24 capreomycin
tlyA 1918077 c.138G>C synonymous_variant 0.24 capreomycin
tlyA 1918078 p.Ser47Ala missense_variant 0.24 capreomycin
tlyA 1918082 p.Asp48Val missense_variant 0.25 capreomycin
tlyA 1918087 p.Thr50Ala missense_variant 0.27 capreomycin
tlyA 1918092 c.153G>C synonymous_variant 0.28 capreomycin
tlyA 1918103 p.Val55Ala missense_variant 0.3 capreomycin
tlyA 1918121 p.Ala61Gly missense_variant 0.3 capreomycin
tlyA 1918128 c.189A>C synonymous_variant 0.28 capreomycin
tlyA 1918137 c.198A>C synonymous_variant 0.29 capreomycin
tlyA 1918149 c.210A>C synonymous_variant 0.29 capreomycin
tlyA 1918150 p.Val71Ile missense_variant 0.28 capreomycin
tlyA 1918155 c.216T>C synonymous_variant 0.29 capreomycin
tlyA 1918164 p.Glu75Asp missense_variant 0.29 capreomycin
tlyA 1918167 c.228G>C synonymous_variant 0.28 capreomycin
tlyA 1918172 p.Ala78Gly missense_variant 0.29 capreomycin
tlyA 1918182 c.243G>C synonymous_variant 0.29 capreomycin
tlyA 1918191 c.252G>C synonymous_variant 0.31 capreomycin
tlyA 1918197 c.258T>C synonymous_variant 0.29 capreomycin
tlyA 1918206 c.267G>C synonymous_variant 0.3 capreomycin
tlyA 1918212 c.273A>G synonymous_variant 0.32 capreomycin
tlyA 1918218 c.279C>G synonymous_variant 0.29 capreomycin
tlyA 1918221 c.282T>C synonymous_variant 0.29 capreomycin
tlyA 1918224 c.285G>C synonymous_variant 0.3 capreomycin
tlyA 1918236 c.297A>C synonymous_variant 0.36 capreomycin
tlyA 1918248 c.309T>C synonymous_variant 0.37 capreomycin
tlyA 1918251 c.312T>G synonymous_variant 0.34 capreomycin
tlyA 1918271 p.Ala111Val missense_variant 0.38 capreomycin
tlyA 1918275 c.336T>C synonymous_variant 0.38 capreomycin
tlyA 1918278 c.339C>G synonymous_variant 0.38 capreomycin
tlyA 1918310 p.Asn124Ser missense_variant 0.33 capreomycin
tlyA 1918323 c.384G>C synonymous_variant 0.26 capreomycin
tlyA 1918326 c.387G>C synonymous_variant 0.26 capreomycin
tlyA 1918330 p.Leu131Val missense_variant 0.27 capreomycin
tlyA 1918346 p.Ala136Val missense_variant 0.26 capreomycin
tlyA 1918352 p.Gly138Asp missense_variant 0.24 capreomycin
tlyA 1918356 c.417C>G synonymous_variant 0.24 capreomycin
tlyA 1918359 c.420A>G synonymous_variant 0.24 capreomycin
tlyA 1918362 c.423G>C synonymous_variant 0.25 capreomycin
tlyA 1918377 c.438T>G synonymous_variant 0.25 capreomycin
tlyA 1918379 p.Arg147Pro missense_variant 0.25 capreomycin
tlyA 1918382 p.Val148Ala missense_variant 0.24 capreomycin
tlyA 1918389 c.450G>C synonymous_variant 0.23 capreomycin
tlyA 1918392 c.453A>C synonymous_variant 0.23 capreomycin
tlyA 1918422 c.483T>C synonymous_variant 0.21 capreomycin
tlyA 1918425 c.486C>A synonymous_variant 0.2 capreomycin
bacA 2064897 c.-169C>G upstream_gene_variant 0.21 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064903 c.-175G>A upstream_gene_variant 0.24 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064912 c.-184A>G upstream_gene_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064915 c.-187G>C upstream_gene_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064933 c.-205A>G upstream_gene_variant 0.32 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064936 c.-208C>G upstream_gene_variant 0.32 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064942 c.-214G>A upstream_gene_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064948 c.-220G>C upstream_gene_variant 0.37 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.41 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064979 c.-251C>T upstream_gene_variant 0.4 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.39 streptomycin
kanamycin
capreomycin
amikacin
ndh 2101756 c.1287G>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2101765 c.1278C>G synonymous_variant 0.29 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>A synonymous_variant 0.28 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>G synonymous_variant 0.28 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2101774 c.1269T>C synonymous_variant 0.28 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.3 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 0.34 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.37 ethionamide
delamanid
isoniazid
ndh 2101808 p.Thr412Ser missense_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2101830 p.Ile405Val missense_variant 0.36 ethionamide
delamanid
isoniazid
ndh 2101837 p.Ala402Val missense_variant 0.39 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101872 p.Ile391Phe missense_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2101873 c.1168_1170delTTTinsCA frameshift_variant&missense_variant 0.35 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2101885 c.1158G>A synonymous_variant 0.34 ethionamide
delamanid
isoniazid
ndh 2101888 c.1155T>C synonymous_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2101894 c.1149T>G synonymous_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 0.36 ethionamide
delamanid
isoniazid
ndh 2101920 c.1123A>C synonymous_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>G synonymous_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2101960 c.1083A>G synonymous_variant 0.22 ethionamide
delamanid
isoniazid
ndh 2102366 p.Ala226Glu missense_variant 0.2 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102368 c.675C>T synonymous_variant 0.2 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102401 c.642T>C synonymous_variant 0.22 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102407 c.636T>C synonymous_variant 0.2 ethionamide
delamanid
isoniazid
ndh 2102413 c.630G>C synonymous_variant 0.2 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 0.23 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>G synonymous_variant 0.28 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 0.27 ethionamide
delamanid
isoniazid
ndh 2102695 c.348C>T synonymous_variant 0.28 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 0.29 ethionamide
delamanid
isoniazid
ndh 2102710 c.333C>T synonymous_variant 0.3 ethionamide
delamanid
isoniazid
ndh 2102718 p.Gln109Glu missense_variant 0.33 ethionamide
delamanid
isoniazid
ndh 2102728 c.315T>A synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102736 c.307T>C synonymous_variant 0.3 ethionamide
delamanid
isoniazid
ndh 2102737 p.Glu102Asp missense_variant 0.3 ethionamide
delamanid
isoniazid
ndh 2102743 c.300C>G synonymous_variant 0.3 ethionamide
delamanid
isoniazid
ndh 2102750 p.Cys98Phe missense_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2102754 p.Gln97Lys missense_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2102755 c.288G>C synonymous_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2102758 c.285C>G synonymous_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2102773 c.270C>G synonymous_variant 0.34 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102781 p.Asn88Asp missense_variant 0.33 ethionamide
delamanid
isoniazid Uncertain significance
ndh 2102785 c.256_258delTTGinsCC frameshift_variant&missense_variant 0.32 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102790 c.253C>T synonymous_variant 0.31 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102791 c.252A>G synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102800 c.243T>C synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2102810 p.Lys78Arg missense_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2102812 c.231T>C synonymous_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2102830 c.213G>C synonymous_variant 0.35 ethionamide
delamanid
isoniazid
ndh 2102836 c.207T>C synonymous_variant 0.33 ethionamide
delamanid
isoniazid
ndh 2102842 p.Glu67Asp missense_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102845 c.198A>C synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102848 c.195G>A synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102854 c.187_189delATCinsGG frameshift_variant&missense_variant 0.3 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102857 c.186T>C synonymous_variant 0.3 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102860 c.183G>C synonymous_variant 0.3 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102863 c.180C>G synonymous_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2102866 c.177C>G synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102872 c.171A>G synonymous_variant 0.32 ethionamide
delamanid
isoniazid
ndh 2102893 c.150G>C synonymous_variant 0.31 ethionamide
delamanid
isoniazid
ndh 2102899 c.144T>C synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102902 c.141C>G synonymous_variant 0.25 ethionamide
delamanid
isoniazid
ndh 2102911 c.132G>C synonymous_variant 0.22 ethionamide
delamanid
isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
pncA 2289906 c.-665T>C upstream_gene_variant 0.24 pyrazinamide
pncA 2289907 c.-666A>C upstream_gene_variant 0.24 pyrazinamide
pncA 2289913 c.-672T>C upstream_gene_variant 0.24 pyrazinamide
pncA 2289925 c.-684T>C upstream_gene_variant 0.26 pyrazinamide
pncA 2289930 c.-689A>G upstream_gene_variant 0.27 pyrazinamide
pncA 2289943 c.-702T>G upstream_gene_variant 0.25 pyrazinamide
pncA 2289948 c.-707C>T upstream_gene_variant 0.26 pyrazinamide
pncA 2289987 c.-746C>T upstream_gene_variant 0.26 pyrazinamide
pncA 2289988 c.-747G>C upstream_gene_variant 0.25 pyrazinamide
pncA 2289991 c.-750G>C upstream_gene_variant 0.24 pyrazinamide
pncA 2289994 c.-753A>G upstream_gene_variant 0.27 pyrazinamide
pncA 2289997 c.-756G>C upstream_gene_variant 0.26 pyrazinamide
pncA 2290000 c.-759C>T upstream_gene_variant 0.25 pyrazinamide
pncA 2290009 c.-768A>C upstream_gene_variant 0.26 pyrazinamide
pncA 2290015 c.-774A>C upstream_gene_variant 0.28 pyrazinamide
pncA 2290024 c.-783C>G upstream_gene_variant 0.3 pyrazinamide
pncA 2290030 c.-791_-789delAATinsCC upstream_gene_variant 0.31 pyrazinamide
pncA 2290033 c.-792C>G upstream_gene_variant 0.31 pyrazinamide
pncA 2290038 c.-797G>A upstream_gene_variant 0.34 pyrazinamide
pncA 2290042 c.-801T>C upstream_gene_variant 0.33 pyrazinamide
pncA 2290069 c.-828C>A upstream_gene_variant 0.26 pyrazinamide
kasA 2517950 c.-165C>G upstream_gene_variant 0.49 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.54 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.53 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.49 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.47 isoniazid
kasA 2518031 c.-84G>C upstream_gene_variant 0.48 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.47 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.47 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.46 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.47 isoniazid
kasA 2518053 c.-62_-60delATTinsCG upstream_gene_variant 0.46 isoniazid
kasA 2518059 c.-56_-54delTCGinsAC upstream_gene_variant 0.46 isoniazid
kasA 2518073 c.-42T>C upstream_gene_variant 0.43 isoniazid
kasA 2518076 c.-39C>G upstream_gene_variant 0.43 isoniazid
kasA 2518079 c.-36T>C upstream_gene_variant 0.43 isoniazid
kasA 2518088 c.-27T>C upstream_gene_variant 0.43 isoniazid
kasA 2518089 c.-26C>A upstream_gene_variant 0.43 isoniazid
kasA 2518094 c.-21G>A upstream_gene_variant 0.44 isoniazid
kasA 2518100 c.-15T>G upstream_gene_variant 0.43 isoniazid
kasA 2518103 c.-12G>A upstream_gene_variant 0.43 isoniazid
kasA 2518106 c.-9C>G upstream_gene_variant 0.44 isoniazid
kasA 2518109 c.-6G>C upstream_gene_variant 0.43 isoniazid
kasA 2518110 c.-5T>A upstream_gene_variant 0.43 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 0.43 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.39 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.4 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.37 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.31 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.22 isoniazid
kasA 2518439 p.Ala109Ser missense_variant 0.21 isoniazid
kasA 2518444 c.330T>C synonymous_variant 0.23 isoniazid
kasA 2518459 c.345T>C synonymous_variant 0.25 isoniazid
kasA 2518462 c.348A>C synonymous_variant 0.25 isoniazid
kasA 2518468 c.354A>C synonymous_variant 0.27 isoniazid
kasA 2518474 c.360G>A synonymous_variant 0.28 isoniazid
kasA 2518480 c.366T>C synonymous_variant 0.28 isoniazid
kasA 2518483 c.369C>G synonymous_variant 0.29 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.34 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.34 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.34 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.35 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.39 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.39 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.37 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.36 isoniazid
kasA 2518574 c.460_462delATCinsGG frameshift_variant&missense_variant 0.38 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.39 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.39 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.39 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.39 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.4 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.41 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.44 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.39 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.39 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.34 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.33 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.33 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.33 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.35 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.31 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.32 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.32 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.31 isoniazid
kasA 2518768 c.654C>T synonymous_variant 0.36 isoniazid
kasA 2518777 c.663C>T synonymous_variant 0.37 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.37 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.34 isoniazid
kasA 2518792 c.678C>A synonymous_variant 0.32 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.33 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.39 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.41 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.39 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.37 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.41 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.44 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.46 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.46 isoniazid
kasA 2518927 c.813C>G synonymous_variant 0.49 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.51 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.51 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.5 isoniazid
kasA 2518951 c.837G>C synonymous_variant 0.54 isoniazid
kasA 2518954 c.840C>G synonymous_variant 0.54 isoniazid
kasA 2518963 c.849T>C synonymous_variant 0.54 isoniazid
kasA 2518969 c.855T>G synonymous_variant 0.54 isoniazid
kasA 2518975 c.861C>G synonymous_variant 0.52 isoniazid
kasA 2518979 c.865A>C synonymous_variant 0.5 isoniazid
kasA 2518990 c.876T>G synonymous_variant 0.46 isoniazid
kasA 2518993 c.879C>G synonymous_variant 0.45 isoniazid
kasA 2518999 c.885G>A synonymous_variant 0.44 isoniazid
kasA 2519008 c.894C>G synonymous_variant 0.46 isoniazid
kasA 2519017 c.903G>C synonymous_variant 0.48 isoniazid
kasA 2519020 c.906G>C synonymous_variant 0.46 isoniazid
kasA 2519021 p.Ala303Lys missense_variant 0.45 isoniazid
kasA 2519027 c.913_915delATCinsGT frameshift_variant&missense_variant 0.45 isoniazid
kasA 2519050 c.936C>G synonymous_variant 0.5 isoniazid
kasA 2519053 c.939G>C synonymous_variant 0.48 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.47 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.43 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.44 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.33 isoniazid
kasA 2519108 c.994_996delGATinsCG frameshift_variant&missense_variant 0.33 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.31 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.31 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.28 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.27 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.26 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.28 isoniazid
ahpC 2726528 c.336C>G synonymous_variant 0.24 isoniazid
ahpC 2726540 c.348C>G synonymous_variant 0.24 isoniazid
ahpC 2726543 c.351A>G synonymous_variant 0.23 isoniazid
ahpC 2726546 c.354C>G synonymous_variant 0.23 isoniazid
ahpC 2726551 p.Gln120Leu missense_variant 0.22 isoniazid
ahpC 2726556 c.364_366delGCAinsAC frameshift_variant&missense_variant 0.22 isoniazid Uncertain significance
ahpC 2726564 c.372C>G synonymous_variant 0.22 isoniazid Not assoc w R - Interim
ahpC 2726579 c.387T>C synonymous_variant 0.21 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.22 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.21 isoniazid Not assoc w R - Interim
Rv2477c 2782513 c.1530G>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782525 c.1518C>T synonymous_variant 0.23 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782586 p.Leu486Gln missense_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782591 c.1452T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782608 p.Gly479Ser missense_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782612 c.1431T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782615 c.1428G>A synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782621 c.1422T>C synonymous_variant 0.22 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782624 c.1419G>C synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782633 c.1410G>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782636 c.1407G>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782639 c.1404A>G synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782651 c.1392T>C synonymous_variant 0.21 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782654 c.1389G>C synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782660 c.1383C>A synonymous_variant 0.28 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782669 c.1374A>G synonymous_variant 0.29 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782680 c.1363T>C synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782684 c.1359T>C synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782695 c.1348A>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782705 c.1338G>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782711 c.1332C>G synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782714 c.1329A>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782720 c.1323T>C synonymous_variant 0.42 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782729 c.1314A>G synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782732 c.1311A>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782741 c.1302G>A synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782750 c.1293T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782759 c.1284A>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782777 c.1266A>G synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782786 c.1257A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782792 c.1251A>G synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782795 c.1248T>C synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782801 p.Gln414Val missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782807 c.1234_1236delTATinsCC frameshift_variant&missense_variant 0.62 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782816 c.1227T>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782822 c.1221G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782828 c.1215T>C synonymous_variant 0.69 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782841 p.Thr401Asn missense_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782847 p.Arg399Lys missense_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782852 c.1191T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 0.61 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782912 p.Ser377Thr missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782927 p.Thr372Glu missense_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 0.59 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782966 c.1077C>A synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.54 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.53 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.49 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.49 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 0.62 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin
amikacin Not assoc w R - Interim
Rv2477c 2783149 c.894G>C synonymous_variant 0.63 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 0.63 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783179 c.864G>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783182 c.861C>G synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783209 c.834G>A synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783293 c.750G>A synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.4 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783329 c.714G>A synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.32 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 c.616_618delCCCinsGG frameshift_variant&missense_variant 0.31 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783428 c.615C>T synonymous_variant 0.29 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783431 c.610_612delAGCinsTCG synonymous_variant 0.28 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783437 c.606G>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783497 c.544_546delTTGinsCC frameshift_variant&missense_variant 0.37 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783502 c.541T>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783521 c.522G>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783554 c.489C>T synonymous_variant 0.46 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783557 c.486T>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.423C>G synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783776 c.267G>C synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783863 c.180C>T synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783887 c.156C>G synonymous_variant 0.53 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783929 c.114C>G synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783932 c.111C>T synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>A synonymous_variant 0.41 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783962 c.81T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783971 c.72G>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2752c 3064832 p.Ala454Thr missense_variant 0.17 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064860 c.1332G>C synonymous_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064872 c.1320T>G synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064877 p.Ser439Ala missense_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064881 p.Ser437Ala missense_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064887 c.1305A>G synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064893 c.1299C>G synonymous_variant 0.28 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064896 c.1296T>C synonymous_variant 0.29 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064914 c.1278T>G synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064926 c.1264_1266delTTGinsCC frameshift_variant&missense_variant 0.27 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064932 c.1260T>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064935 c.1257A>G synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 0.26 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064947 c.1245A>G synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064955 c.1233_1236delCAGT frameshift_variant 0.25 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064962 c.1229_1230insGATC frameshift_variant 0.25 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064973 p.Ala407Ser missense_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064995 c.1197C>G synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>G synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065007 c.1185G>C synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065013 c.1179G>C synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065018 p.Asn392His missense_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065028 c.1162_1164delGTGinsAC frameshift_variant&missense_variant 0.4 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065040 c.1152C>G synonymous_variant 0.42 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 0.42 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065052 c.1140G>A synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>C synonymous_variant 0.41 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 0.38 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065082 c.1110G>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065087 c.1105A>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid Not assoc w R - Interim
Rv2752c 3065088 c.1104A>G synonymous_variant 0.35 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 0.38 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065115 c.1077C>A synonymous_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065126 p.Ser356Ala missense_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065127 c.1065G>C synonymous_variant 0.31 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 p.Ala354Glu missense_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>C synonymous_variant 0.41 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065151 c.1041G>C synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065183 p.Ser337Ala missense_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065190 c.1000_1002delATCinsGG frameshift_variant&missense_variant 0.32 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065196 c.996T>C synonymous_variant 0.32 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>G synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065205 c.987T>C synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065210 c.982T>C synonymous_variant 0.32 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065223 c.969T>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065229 c.963G>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065262 c.930G>A synonymous_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065397 c.795G>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065400 c.792A>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065412 c.780G>A synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065418 c.774A>G synonymous_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065421 c.771G>A synonymous_variant 0.37 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065442 c.750T>C synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065451 c.741G>A synonymous_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065457 c.735A>C synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065463 c.729T>C synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065481 c.711T>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065487 c.705T>G synonymous_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065490 c.702A>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065493 c.699G>C synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065499 c.693A>C synonymous_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065502 p.Asp230Glu missense_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065508 c.684T>C synonymous_variant 0.35 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065511 c.681G>C synonymous_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065517 c.675C>G synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065523 c.669C>T synonymous_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065532 c.660A>G synonymous_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065535 c.657C>T synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065538 c.654G>C synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065541 c.651A>G synonymous_variant 0.39 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065553 c.639A>G synonymous_variant 0.44 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065562 c.630T>C synonymous_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065569 p.Ile208His missense_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065586 c.606C>T synonymous_variant 0.43 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065595 p.Leu199Phe missense_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065598 c.594G>T synonymous_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065607 c.585C>G synonymous_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065612 p.Thr194Ala missense_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065616 c.576C>T synonymous_variant 0.35 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065622 c.570G>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065625 c.567G>C synonymous_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065634 c.558G>C synonymous_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065637 c.555A>G synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065646 c.546C>G synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.543T>G synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065659 p.Pro178Leu missense_variant 0.25 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065664 c.526_528delTTGinsCT frameshift_variant&missense_variant 0.25 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065675 p.Phe173Leu missense_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.21 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066009 c.183G>C synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>G synonymous_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.24 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066074 c.118C>T synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066075 c.117A>G synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066078 c.114C>T synonymous_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066102 c.90C>T synonymous_variant 0.32 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066118 p.Asn25Ser missense_variant 0.27 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066276 c.-85G>A upstream_gene_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066282 c.-91G>T upstream_gene_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066287 c.-96G>C upstream_gene_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066290 c.-99G>A upstream_gene_variant 0.21 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066291 c.-100G>A upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066315 c.-124C>T upstream_gene_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066330 c.-139G>C upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066360 c.-169T>C upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066369 c.-180_-178delAGCinsGCG upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066380 c.-189A>G upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066396 c.-207_-205delGCGinsAC upstream_gene_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066399 c.-210_-208delATTinsTCC upstream_gene_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066435 c.-246_-244delGGTinsAAC upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066452 c.-261T>A upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066453 c.-262G>A upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066456 c.-265A>G upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066462 c.-271G>A upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-276_-274delGGGinsAAT upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>G upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066476 c.-285C>G upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066482 c.-291G>T upstream_gene_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066483 c.-292T>C upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.51 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066522 c.-331C>G upstream_gene_variant 0.49 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066531 c.-340C>G upstream_gene_variant 0.46 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066561 c.-370A>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>G upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066582 c.-392_-391delCCinsGG upstream_gene_variant 0.32 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.25 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066734 c.-543G>A upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066758 c.-567C>A upstream_gene_variant 0.2 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066762 c.-571G>C upstream_gene_variant 0.23 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066771 c.-580C>G upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066774 c.-583T>C upstream_gene_variant 0.26 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066780 c.-589C>G upstream_gene_variant 0.3 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.36 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.34 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066839 c.-648A>G upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066855 c.-664T>C upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066859 c.-668C>G upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066864 c.-673C>G upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066867 c.-676T>C upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066876 c.-685T>C upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066879 c.-688T>C upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066891 c.-700G>C upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066900 c.-709A>G upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066905 c.-714T>C upstream_gene_variant 0.4 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066906 c.-715C>G upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066910 c.-719C>T upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066912 c.-721G>C upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066924 c.-735_-733delATCinsCGG upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066927 c.-736A>G upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066933 c.-743_-742delGGinsAC upstream_gene_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066960 c.-769C>G upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066969 c.-778G>C upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066981 c.-790T>G upstream_gene_variant 0.33 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066987 c.-796C>T upstream_gene_variant 0.3 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066995 c.-804C>G upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066996 c.-805T>C upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3067001 c.-810G>A upstream_gene_variant 0.22 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067252 p.Val232Met missense_variant 0.22 para-aminosalicylic_acid
thyX 3067274 c.672C>G synonymous_variant 0.27 para-aminosalicylic_acid
thyX 3067277 c.669C>G synonymous_variant 0.28 para-aminosalicylic_acid
thyX 3067281 p.Val222Ala missense_variant 0.3 para-aminosalicylic_acid
thyX 3067284 p.Ala221Gly missense_variant 0.3 para-aminosalicylic_acid
thyX 3067286 c.660C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067289 c.657C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067292 c.654G>A synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067295 c.651C>T synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.34 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067367 c.579G>C synonymous_variant 0.37 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067376 c.570G>A synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 0.56 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.56 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 0.6 para-aminosalicylic_acid
thyX 3067530 p.Ala139Ser missense_variant 0.58 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 0.6 para-aminosalicylic_acid
thyX 3067549 p.Thr133Ala missense_variant 0.59 para-aminosalicylic_acid
thyX 3067556 p.His130Gln missense_variant 0.57 para-aminosalicylic_acid
thyX 3067559 c.387C>G synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 0.59 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 0.6 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 0.57 para-aminosalicylic_acid
thyX 3067583 c.363C>G synonymous_variant 0.59 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 0.54 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 0.54 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.51 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.51 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.51 para-aminosalicylic_acid
thyX 3067685 c.261A>C synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067691 c.253_255delATCinsCG frameshift_variant&missense_variant 0.51 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.51 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.49 para-aminosalicylic_acid
thyX 3067736 c.208_210delTTCinsCT frameshift_variant&missense_variant 0.49 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.48 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.42 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.42 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067781 c.165C>A synonymous_variant 0.45 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.41 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.36 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.31 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.3 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.29 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.27 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.25 para-aminosalicylic_acid
thyA 3073860 c.612C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 0.22 para-aminosalicylic_acid
thyA 3073917 c.555C>G synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.31 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3074010 c.462C>G synonymous_variant 0.35 para-aminosalicylic_acid
thyA 3074028 c.444G>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.39 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.45 para-aminosalicylic_acid
thyA 3074055 p.Glu139Pro missense_variant 0.44 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074079 c.393G>C synonymous_variant 0.42 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3074100 c.370_372delGATinsAC frameshift_variant&synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 0.37 para-aminosalicylic_acid
thyA 3074127 c.345G>C synonymous_variant 0.34 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 0.23 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.22 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAG frameshift_variant&missense_variant 0.22 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.26 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.3 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.3 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.29 para-aminosalicylic_acid
thyA 3074241 c.231C>G synonymous_variant 0.25 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.24 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
lpqB 3623291 c.1620C>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623393 c.1518A>C synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3623411 c.1500T>C synonymous_variant 0.25 bedaquiline
rifampicin
lpqB 3623417 c.1494A>C synonymous_variant 0.26 bedaquiline
rifampicin
lpqB 3623423 c.1488C>G synonymous_variant 0.26 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623428 c.1483T>C synonymous_variant 0.26 bedaquiline
rifampicin
lpqB 3623441 p.Ser490Asn missense_variant 0.23 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 0.23 bedaquiline
rifampicin
lpqB 3623449 c.1462C>T synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3623465 c.1446G>C synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3623468 c.1443T>A synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3623471 c.1440C>T synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3623484 p.Phe476Tyr missense_variant 0.22 bedaquiline
rifampicin
lpqB 3623492 c.1419T>C synonymous_variant 0.27 bedaquiline
rifampicin
lpqB 3623512 p.Gly467Ser missense_variant 0.27 bedaquiline
rifampicin
lpqB 3623528 c.1383G>C synonymous_variant 0.3 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623531 c.1380T>C synonymous_variant 0.32 bedaquiline
rifampicin
lpqB 3623549 c.1362C>G synonymous_variant 0.4 bedaquiline
rifampicin
lpqB 3623555 c.1354_1356delGGGinsAC frameshift_variant&missense_variant 0.42 bedaquiline
rifampicin Uncertain significance
lpqB 3623561 c.1350T>C synonymous_variant 0.41 bedaquiline
rifampicin
lpqB 3623570 c.1341A>G synonymous_variant 0.41 bedaquiline
rifampicin
lpqB 3623573 c.1336_1338delCTTinsTG frameshift_variant&synonymous_variant 0.39 bedaquiline
rifampicin Uncertain significance
lpqB 3623580 p.Asn444Thr missense_variant 0.43 bedaquiline
rifampicin
lpqB 3623587 p.Ala442Pro missense_variant 0.42 bedaquiline
rifampicin
lpqB 3623597 c.1314C>G synonymous_variant 0.4 bedaquiline
rifampicin
lpqB 3623601 p.Ser437Thr missense_variant 0.4 bedaquiline
rifampicin
lpqB 3623612 p.Thr433Val missense_variant 0.37 bedaquiline
rifampicin
lpqB 3623630 c.1281G>C synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3623648 c.1263A>G synonymous_variant 0.29 bedaquiline
rifampicin
lpqB 3623654 p.Asp419Glu missense_variant 0.26 bedaquiline
rifampicin
lpqB 3623660 c.1251A>C synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3623666 c.1245A>C synonymous_variant 0.24 bedaquiline
rifampicin
lpqB 3623669 c.1242G>C synonymous_variant 0.23 bedaquiline
rifampicin
lpqB 3623676 p.Val412Asn missense_variant 0.23 bedaquiline
rifampicin
lpqB 3623681 c.1230C>G synonymous_variant 0.23 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623684 c.1227T>C synonymous_variant 0.22 bedaquiline
rifampicin
lpqB 3623693 c.1218G>C synonymous_variant 0.26 bedaquiline
rifampicin
lpqB 3623703 p.Ala403Val missense_variant 0.28 bedaquiline
rifampicin
lpqB 3623705 c.1206C>T synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3623721 p.Ser397Thr missense_variant 0.26 bedaquiline
rifampicin
lpqB 3623953 c.958T>C synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3623962 c.949T>C synonymous_variant 0.29 bedaquiline
rifampicin
lpqB 3623966 c.945G>C synonymous_variant 0.3 bedaquiline
rifampicin
lpqB 3623970 p.Ala314Gly missense_variant 0.29 bedaquiline
rifampicin
lpqB 3623972 c.939C>G synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3623975 c.936T>C synonymous_variant 0.29 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623987 c.924G>C synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3623990 c.921G>C synonymous_variant 0.28 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623993 c.918C>T synonymous_variant 0.29 bedaquiline
rifampicin
lpqB 3624014 c.897T>C synonymous_variant 0.33 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624026 p.Glu295Asp missense_variant 0.29 bedaquiline
rifampicin
lpqB 3624030 p.Ala294Arg missense_variant 0.28 bedaquiline
rifampicin
lpqB 3624032 c.879T>C synonymous_variant 0.28 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624037 c.874A>C synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3624041 p.Glu290Asp missense_variant 0.29 bedaquiline
rifampicin
lpqB 3624050 c.861C>G synonymous_variant 0.33 bedaquiline
rifampicin
lpqB 3624077 c.834G>A synonymous_variant 0.32 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624082 c.829A>C synonymous_variant 0.32 bedaquiline
rifampicin
lpqB 3624086 c.825C>T synonymous_variant 0.31 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624092 c.817_819delAGGinsCC frameshift_variant&missense_variant 0.32 bedaquiline
rifampicin Uncertain significance
lpqB 3624100 c.811T>C synonymous_variant 0.31 bedaquiline
rifampicin
lpqB 3624101 c.810C>G synonymous_variant 0.31 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 0.33 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624116 c.795A>G synonymous_variant 0.36 bedaquiline
rifampicin
lpqB 3624119 c.792C>G synonymous_variant 0.36 bedaquiline
rifampicin
lpqB 3624124 p.Leu263Val missense_variant 0.37 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.37 bedaquiline
rifampicin
lpqB 3624143 c.768T>C synonymous_variant 0.42 bedaquiline
rifampicin
lpqB 3624166 p.Met249Leu missense_variant 0.4 bedaquiline
rifampicin
lpqB 3624167 c.744C>T synonymous_variant 0.39 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624173 c.738A>C synonymous_variant 0.38 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624179 c.732C>G synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3624185 c.726C>T synonymous_variant 0.44 bedaquiline
rifampicin
lpqB 3624194 c.717C>G synonymous_variant 0.41 bedaquiline
rifampicin
lpqB 3624200 c.711A>G synonymous_variant 0.4 bedaquiline
rifampicin
lpqB 3624204 p.Ser236Asn missense_variant 0.4 bedaquiline
rifampicin
lpqB 3624209 c.702A>C synonymous_variant 0.43 bedaquiline
rifampicin
lpqB 3624224 c.687T>C synonymous_variant 0.46 bedaquiline
rifampicin
lpqB 3624242 c.669A>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624245 c.666A>G synonymous_variant 0.48 bedaquiline
rifampicin
lpqB 3624254 c.657T>C synonymous_variant 0.43 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624263 c.648T>C synonymous_variant 0.38 bedaquiline
rifampicin
lpqB 3624266 c.645T>C synonymous_variant 0.38 bedaquiline
rifampicin
lpqB 3624269 c.642G>C synonymous_variant 0.37 bedaquiline
rifampicin
lpqB 3624276 p.Arg212His missense_variant 0.4 bedaquiline
rifampicin
lpqB 3624290 c.621C>G synonymous_variant 0.38 bedaquiline
rifampicin
lpqB 3624296 c.615T>G synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3624299 c.612G>C synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3624302 c.607_609delCTGinsAC frameshift_variant&missense_variant 0.33 bedaquiline
rifampicin Uncertain significance
lpqB 3624308 c.603A>G synonymous_variant 0.34 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624314 c.597C>G synonymous_variant 0.34 bedaquiline
rifampicin
lpqB 3624317 c.594C>G synonymous_variant 0.36 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 0.35 bedaquiline
rifampicin
lpqB 3624326 c.585C>G synonymous_variant 0.35 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624331 c.580C>T synonymous_variant 0.37 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 0.34 bedaquiline
rifampicin
lpqB 3624346 p.Ser189Pro missense_variant 0.34 bedaquiline
rifampicin
lpqB 3624356 c.555C>T synonymous_variant 0.34 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624371 c.540T>C synonymous_variant 0.3 bedaquiline
rifampicin
lpqB 3624455 c.456G>A synonymous_variant 0.22 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624556 p.Val119Met missense_variant 0.21 bedaquiline
rifampicin Uncertain significance
lpqB 3624632 c.279G>C synonymous_variant 0.28 bedaquiline
rifampicin
lpqB 3624635 c.276C>T synonymous_variant 0.29 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 0.3 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.3 bedaquiline
rifampicin
lpqB 3624660 p.Ala84Gly missense_variant 0.66 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3624701 c.210T>C synonymous_variant 0.23 bedaquiline
rifampicin
lpqB 3624704 c.207G>C synonymous_variant 0.23 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 0.21 bedaquiline
rifampicin
lpqB 3625051 c.-141C>T upstream_gene_variant 0.24 bedaquiline
rifampicin
lpqB 3625057 c.-147C>G upstream_gene_variant 0.28 bedaquiline
rifampicin
lpqB 3625060 c.-150G>C upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625093 p.Glu507Asp missense_variant 0.29 bedaquiline
rifampicin
lpqB 3625099 c.-189C>G upstream_gene_variant 0.3 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 0.31 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.32 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.33 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 0.33 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 0.33 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 0.33 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.34 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.35 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 0.35 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625165 c.-255G>C upstream_gene_variant 0.35 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 0.38 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.4 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.46 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrB 3625206 p.Ser470Ala missense_variant 0.47 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.43 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625225 c.-315G>C upstream_gene_variant 0.41 bedaquiline
rifampicin
lpqB 3625240 c.-330T>C upstream_gene_variant 0.43 bedaquiline
rifampicin
lpqB 3625243 c.-333T>G upstream_gene_variant 0.49 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.44 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.44 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.23 bedaquiline
rifampicin
lpqB 3625543 c.-633G>C upstream_gene_variant 0.26 bedaquiline
rifampicin
lpqB 3625549 c.-639G>A upstream_gene_variant 0.35 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.37 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.38 bedaquiline
rifampicin
lpqB 3625579 c.-669A>G upstream_gene_variant 0.4 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.41 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.43 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3625616 p.Arg333Ala missense_variant 0.46 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.49 bedaquiline
rifampicin
mtrB 3625636 c.978C>G synonymous_variant 0.54 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.57 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.56 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.61 bedaquiline
rifampicin
mtrB 3625720 c.894G>C synonymous_variant 0.61 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.61 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.63 bedaquiline
rifampicin
lpqB 3625749 c.-839C>T upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3625750 c.864G>A synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.59 bedaquiline
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625797 p.Val273Met missense_variant 0.52 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625806 c.808A>C synonymous_variant 0.51 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625807 c.807C>G synonymous_variant 0.51 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.53 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625849 c.-939T>C upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.48 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 0.41 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625900 c.-990G>C upstream_gene_variant 0.28 bedaquiline
rifampicin
lpqB 3625903 c.-993G>C upstream_gene_variant 0.27 bedaquiline
rifampicin
lpqB 3625909 c.-999T>C upstream_gene_variant 0.25 bedaquiline
rifampicin
mtrB 3625923 c.691C>T synonymous_variant 0.26 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.26 bedaquiline
rifampicin
mtrB 3625930 c.684C>G synonymous_variant 0.25 bedaquiline
rifampicin
mtrB 3625936 c.678C>G synonymous_variant 0.24 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625942 c.672C>G synonymous_variant 0.22 bedaquiline
rifampicin
mtrB 3626308 c.306T>C synonymous_variant 0.2 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626704 c.-91C>T upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrA 3626723 c.627C>T synonymous_variant 0.29 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626726 c.-113T>C upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.28 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.29 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.32 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.3 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.31 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.32 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.31 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626795 c.-182C>T upstream_gene_variant 0.36 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 0.36 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.37 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.47 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626866 c.-253T>C upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626912 c.-299T>G upstream_gene_variant 0.43 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.44 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.5 bedaquiline
rifampicin
mtrB 3627065 c.-452G>C upstream_gene_variant 0.46 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.47 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627071 c.279G>T synonymous_variant 0.48 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 0.49 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.48 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.51 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.53 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 0.58 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627209 c.-596G>A upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrA 3627221 c.129C>T synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627227 c.123T>C synonymous_variant 0.57 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627233 c.-620T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.56 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.56 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3627275 c.-662G>T upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCA frameshift_variant&missense_variant 0.54 bedaquiline
rifampicin
mtrB 3627314 c.-701C>T upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.39 bedaquiline
rifampicin
mtrB 3627360 c.-747G>C upstream_gene_variant 0.29 bedaquiline
rifampicin
mtrB 3627375 c.-762C>G upstream_gene_variant 0.22 bedaquiline
rifampicin
mtrB 3627380 c.-767T>C upstream_gene_variant 0.2 bedaquiline
rifampicin
fbiA 3640900 p.Gln120Lys missense_variant 0.22 clofazimine
pretomanid
delamanid
rpoA 3877494 p.Glu338Asp missense_variant 0.31 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.35 rifampicin
rpoA 3877507 p.Gly334Ala missense_variant 0.33 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.36 rifampicin
rpoA 3877553 p.Glu319Gln missense_variant 0.55 rifampicin
rpoA 3877571 p.Pro313Ala missense_variant 0.58 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.58 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.55 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 0.57 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.59 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.64 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.62 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.65 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.62 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 0.61 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.65 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.65 rifampicin
rpoA 3877900 p.Ser203Asn missense_variant 0.63 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3877909 p.Asn200Ser missense_variant 0.64 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.65 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoA 3877986 c.522G>C synonymous_variant 0.65 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.62 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.62 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.61 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 0.61 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.61 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.61 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.6 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.6 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.6 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.61 rifampicin
rpoA 3878082 c.426T>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878094 c.414C>G synonymous_variant 0.58 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.57 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.57 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.55 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.56 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.54 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.54 rifampicin Uncertain significance
rpoA 3878157 c.351C>G synonymous_variant 0.6 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoA 3878169 c.339G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.59 rifampicin
rpoA 3878181 c.327C>T synonymous_variant 0.61 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.61 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 0.6 rifampicin
rpoA 3878217 c.291A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.62 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.62 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.58 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878284 p.Glu75Ala missense_variant 0.64 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.7 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3878340 c.168C>T synonymous_variant 0.72 rifampicin
rpoA 3878346 c.162T>C synonymous_variant 0.71 rifampicin
rpoA 3878364 c.144A>T synonymous_variant 0.66 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.66 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.66 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.62 rifampicin
rpoA 3878388 c.120C>G synonymous_variant 0.62 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 0.62 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 0.64 rifampicin
rpoA 3878424 c.84G>C synonymous_variant 0.63 rifampicin
rpoA 3878436 c.72A>G synonymous_variant 0.59 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.59 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 0.54 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.47 rifampicin
rpoA 3878478 c.30C>G synonymous_variant 0.45 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.43 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.47 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.48 rifampicin
rpoA 3878665 c.-158A>G upstream_gene_variant 0.6 rifampicin Uncertain significance
rpoA 3878672 c.-165A>T upstream_gene_variant 0.56 rifampicin
rpoA 3878683 c.-176G>C upstream_gene_variant 0.54 rifampicin
rpoA 3878713 c.-206G>A upstream_gene_variant 0.5 rifampicin Uncertain significance
rpoA 3878716 c.-209C>G upstream_gene_variant 0.51 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.54 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.48 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.51 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.53 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.53 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.53 rifampicin
rpoA 3878761 c.-254G>C upstream_gene_variant 0.53 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 0.5 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.52 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 0.51 rifampicin Uncertain significance
rpoA 3878806 c.-299C>G upstream_gene_variant 0.55 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.54 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.52 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.52 rifampicin
rpoA 3878836 c.-331_-329delAAGinsTCC upstream_gene_variant 0.5 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.55 rifampicin
rpoA 3878860 c.-353C>T upstream_gene_variant 0.58 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.63 rifampicin Uncertain significance
rpoA 3878909 c.-402A>G upstream_gene_variant 0.65 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.67 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.69 rifampicin Uncertain significance
rpoA 3878938 c.-431T>A upstream_gene_variant 0.69 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878962 c.-455G>A upstream_gene_variant 0.69 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878976 c.-469A>G upstream_gene_variant 0.7 rifampicin Uncertain significance
rpoA 3878986 c.-479G>C upstream_gene_variant 0.71 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.75 rifampicin Uncertain significance
rpoA 3879005 c.-499_-498delAAinsCG upstream_gene_variant 0.7 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.72 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.67 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.7 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.69 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.64 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.62 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.54 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.55 rifampicin
rpoA 3879178 c.-671T>C upstream_gene_variant 0.55 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.53 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.46 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.45 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.45 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.45 rifampicin
ddn 3986636 c.-208C>G upstream_gene_variant 0.42 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.34 delamanid
pretomanid
ddn 3986665 c.-179G>C upstream_gene_variant 0.26 delamanid
pretomanid
clpC1 4038255 p.Val817Lys missense_variant 0.2 pyrazinamide
clpC1 4038274 p.Gly811Ser missense_variant 0.2 pyrazinamide
clpC1 4038293 c.2412G>C synonymous_variant 0.25 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.25 pyrazinamide
clpC1 4038308 c.2395_2397delGTGinsAT frameshift_variant&missense_variant 0.25 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 0.26 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.26 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.27 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.39 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.39 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.41 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.43 pyrazinamide
clpC1 4038392 c.2313C>T synonymous_variant 0.44 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.44 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 0.42 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.43 pyrazinamide
clpC1 4038433 c.2272C>T synonymous_variant 0.4 pyrazinamide
clpC1 4038434 c.2271G>A synonymous_variant 0.4 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.4 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.41 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.42 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 0.43 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.38 pyrazinamide
clpC1 4038489 p.Ala739Gly missense_variant 0.38 pyrazinamide
clpC1 4038494 c.2211G>C synonymous_variant 0.38 pyrazinamide
clpC1 4038497 p.Ser736Gln missense_variant 0.37 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.4 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.41 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.46 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.46 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.45 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.44 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.44 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.44 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.45 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.49 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.48 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.5 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.49 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.5 pyrazinamide
clpC1 4038749 c.1956C>G synonymous_variant 0.55 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.55 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 0.51 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.52 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.53 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.55 pyrazinamide
clpC1 4038821 c.1884G>A synonymous_variant 0.56 pyrazinamide
clpC1 4038845 c.1860G>C synonymous_variant 0.6 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 0.57 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
clpC1 4038908 c.1797C>G synonymous_variant 0.57 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.58 pyrazinamide
clpC1 4038923 c.1780_1782delCTAinsTG frameshift_variant&synonymous_variant 0.57 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.56 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.57 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.54 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.5 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.51 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.51 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.53 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.52 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.48 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.46 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.46 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.46 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.43 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.44 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4039229 c.1476C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 0.4 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.43 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.41 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 0.41 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.4 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.43 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.4 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.39 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.41 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 0.43 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.44 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.47 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039480 c.1225C>A synonymous_variant 0.45 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.47 pyrazinamide Not assoc w R - Interim
clpC1 4039517 c.1188C>G synonymous_variant 0.54 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.5 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.5 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.5 pyrazinamide Uncertain significance
clpC1 4039576 p.Ala377Pro missense_variant 0.48 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.49 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.49 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.48 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.48 pyrazinamide
clpC1 4039625 c.1080G>A synonymous_variant 0.47 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.44 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.43 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.44 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.41 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.43 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.42 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.41 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.41 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.41 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.41 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 0.45 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 0.45 pyrazinamide
clpC1 4039826 c.879C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.47 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.44 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.43 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.48 pyrazinamide
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.47 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.46 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.48 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.49 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.49 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.46 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.44 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.45 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.43 pyrazinamide
clpC1 4040036 c.669C>G synonymous_variant 0.43 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.38 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.39 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.49 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.52 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.55 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.53 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.53 pyrazinamide
clpC1 4040210 c.495G>C synonymous_variant 0.53 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.53 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.54 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.53 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.53 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.56 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.57 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.56 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.54 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.53 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.53 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.51 pyrazinamide
clpC1 4040318 c.387C>G synonymous_variant 0.5 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.5 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.45 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.46 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.43 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.39 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.37 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.38 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.4 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.35 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.33 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.31 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.27 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.28 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.28 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.26 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.26 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.27 pyrazinamide
clpC1 4040501 c.204C>T synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.3 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.3 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.29 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.3 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.29 pyrazinamide
clpC1 4040567 c.138C>G synonymous_variant 0.29 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.28 pyrazinamide
clpC1 4040573 c.132T>C synonymous_variant 0.29 pyrazinamide Not assoc w R - Interim
clpC1 4040582 c.123G>C synonymous_variant 0.28 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.29 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.28 pyrazinamide
clpC1 4040596 c.109C>T synonymous_variant 0.25 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.25 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCG frameshift_variant&missense_variant 0.26 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.26 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.26 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.22 pyrazinamide
panD 4044635 c.-354G>C upstream_gene_variant 0.22 pyrazinamide
panD 4044643 c.-362G>T upstream_gene_variant 0.23 pyrazinamide
panD 4044647 c.-366C>G upstream_gene_variant 0.23 pyrazinamide
panD 4044650 c.-369G>C upstream_gene_variant 0.23 pyrazinamide
panD 4044662 c.-381C>G upstream_gene_variant 0.22 pyrazinamide
panD 4044668 c.-387G>C upstream_gene_variant 0.22 pyrazinamide
panD 4044672 c.-391C>A upstream_gene_variant 0.19 pyrazinamide
panD 4044682 c.-401C>A upstream_gene_variant 0.21 pyrazinamide
panD 4044700 c.-419C>A upstream_gene_variant 0.26 pyrazinamide
panD 4044704 c.-423G>C upstream_gene_variant 0.25 pyrazinamide
panD 4044712 c.-431C>A upstream_gene_variant 0.24 pyrazinamide
panD 4044725 c.-444C>T upstream_gene_variant 0.27 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 0.32 pyrazinamide
panD 4044746 c.-467_-465delGTGinsAC upstream_gene_variant 0.33 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 0.33 pyrazinamide
panD 4044758 c.-477C>T upstream_gene_variant 0.33 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 0.31 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 0.33 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 0.33 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.34 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.38 pyrazinamide
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 0.39 pyrazinamide
panD 4044823 c.-542G>C upstream_gene_variant 0.39 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 0.39 pyrazinamide
panD 4044848 c.-567T>G upstream_gene_variant 0.38 pyrazinamide
panD 4044854 c.-573A>G upstream_gene_variant 0.4 pyrazinamide
panD 4044860 c.-579C>G upstream_gene_variant 0.36 pyrazinamide
panD 4044872 c.-591C>G upstream_gene_variant 0.34 pyrazinamide
panD 4044890 c.-609G>C upstream_gene_variant 0.32 pyrazinamide
panD 4044895 c.-614A>G upstream_gene_variant 0.32 pyrazinamide
panD 4044896 c.-615T>G upstream_gene_variant 0.32 pyrazinamide
panD 4044902 c.-623_-621delACGinsGC upstream_gene_variant 0.32 pyrazinamide
panD 4044908 c.-628_-627delCTinsTC upstream_gene_variant 0.32 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 0.31 pyrazinamide
panD 4044920 c.-639C>T upstream_gene_variant 0.31 pyrazinamide
panD 4044926 c.-645C>A upstream_gene_variant 0.29 pyrazinamide
panD 4044929 c.-648G>C upstream_gene_variant 0.3 pyrazinamide
panD 4044935 c.-656_-654delCAAinsTTG upstream_gene_variant 0.3 pyrazinamide
panD 4044941 c.-660G>C upstream_gene_variant 0.32 pyrazinamide
panD 4044954 c.-674_-673delCCinsAT upstream_gene_variant 0.31 pyrazinamide
panD 4044959 c.-678C>G upstream_gene_variant 0.34 pyrazinamide
panD 4044980 c.-699A>G upstream_gene_variant 0.41 pyrazinamide
panD 4044983 c.-702G>T upstream_gene_variant 0.41 pyrazinamide
panD 4044986 c.-705C>G upstream_gene_variant 0.4 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.41 pyrazinamide
panD 4045000 c.-719A>C upstream_gene_variant 0.4 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.41 pyrazinamide
panD 4045019 c.-738G>C upstream_gene_variant 0.4 pyrazinamide
panD 4045022 c.-741C>G upstream_gene_variant 0.4 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.38 pyrazinamide
panD 4045034 c.-753A>C upstream_gene_variant 0.38 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.35 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.28 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.28 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.26 pyrazinamide
panD 4045088 c.-807T>C upstream_gene_variant 0.28 pyrazinamide
panD 4045094 c.-813T>C upstream_gene_variant 0.26 pyrazinamide
panD 4045097 c.-816T>C upstream_gene_variant 0.26 pyrazinamide
glpK 4138451 c.1305T>C synonymous_variant 0.31 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138535 c.1221T>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138565 c.1191G>C synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>A synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138601 c.1155G>C synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138607 c.1149G>A synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138610 c.1146C>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 0.55 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138670 c.1086G>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.56 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138695 p.Pro354Asp missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.51 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138774 p.Ser328Ala missense_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138796 c.960A>G synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138802 c.954G>A synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138808 c.948G>T synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138822 p.Asn312Asp missense_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138829 c.927A>G synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138838 c.918G>C synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138841 c.915G>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138847 c.909A>G synonymous_variant 0.34 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138853 c.903C>G synonymous_variant 0.31 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139195 c.561G>T synonymous_variant 0.21 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139198 c.558C>G synonymous_variant 0.24 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139207 c.549T>C synonymous_variant 0.3 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139231 c.525A>C synonymous_variant 0.25 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139243 c.513A>G synonymous_variant 0.22 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139408 c.348T>C synonymous_variant 0.23 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139417 c.339A>C synonymous_variant 0.24 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139420 c.336T>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139432 c.324C>T synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139447 c.307_309delCACinsAG frameshift_variant&missense_variant 0.37 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139450 c.306G>C synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139453 c.303T>C synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139459 c.297A>C synonymous_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139474 c.282T>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139477 c.279A>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139483 c.273C>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139486 c.270T>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139489 c.267G>T synonymous_variant 0.41 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139494 c.262T>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139504 c.250_252delGATinsAC frameshift_variant&synonymous_variant 0.43 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139515 p.Ser81Ala missense_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139516 c.240A>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139524 p.Thr78Ala missense_variant 0.47 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139526 p.Ala77Arg missense_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139537 c.219G>C synonymous_variant 0.49 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139541 p.Ile72Thr missense_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139545 c.211T>C synonymous_variant 0.48 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139552 c.202_204delGCGinsTC frameshift_variant&missense_variant 0.47 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139561 c.195G>A synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139581 p.Asn59Asp missense_variant 0.48 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139588 c.168G>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139597 c.159C>G synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Gln missense_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139611 p.Ile49Val missense_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139615 c.141G>A synonymous_variant 0.37 ethambutol
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139651 c.103_105delCACinsGG frameshift_variant&missense_variant 0.28 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
embC 4240123 c.261C>G synonymous_variant 0.24 ethambutol
embC 4240126 c.264C>T synonymous_variant 0.24 ethambutol
embC 4240258 c.396T>G synonymous_variant 0.21 ethambutol
embC 4240318 c.456T>C synonymous_variant 0.22 ethambutol
embC 4240325 c.463T>C synonymous_variant 0.24 ethambutol
embC 4240330 c.468A>G synonymous_variant 0.24 ethambutol
embC 4240348 c.486T>C synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embC 4240355 p.Ala165Thr missense_variant 0.21 ethambutol Uncertain significance
embC 4240512 p.Ser217Thr missense_variant 0.24 ethambutol
embC 4240516 c.654G>C synonymous_variant 0.24 ethambutol
embC 4240519 c.657T>C synonymous_variant 0.24 ethambutol
embC 4240543 c.681G>C synonymous_variant 0.34 ethambutol
embC 4240592 p.Ala244Ser missense_variant 0.18 ethambutol
embC 4240630 c.768C>A synonymous_variant 0.28 ethambutol
embC 4240632 p.Met257Thr missense_variant 0.28 ethambutol
embC 4240642 c.780G>C synonymous_variant 0.27 ethambutol
embC 4240645 c.783G>C synonymous_variant 0.26 ethambutol
embC 4240669 c.807G>C synonymous_variant 0.31 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.31 ethambutol Not assoc w R
embC 4240677 p.Gly272Ala missense_variant 0.3 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.29 ethambutol
embC 4240693 c.831T>G synonymous_variant 0.28 ethambutol
embC 4240699 c.837C>G synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 0.36 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.36 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.35 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.38 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.38 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.4 ethambutol
embC 4240867 c.1005T>C synonymous_variant 0.45 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.43 ethambutol
embC 4240873 c.1011C>G synonymous_variant 0.43 ethambutol
embC 4240879 c.1017G>C synonymous_variant 0.44 ethambutol
embC 4240880 p.Ala340Thr missense_variant 0.44 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 0.43 ethambutol
embC 4240897 c.1035C>G synonymous_variant 0.44 ethambutol Not assoc w R
embC 4240898 c.1036_1038delCTAinsTG frameshift_variant&stop_gained 0.44 ethambutol
embC 4240903 c.1041C>G synonymous_variant 0.45 ethambutol
embC 4240911 p.Ala350Val missense_variant 0.47 ethambutol
embC 4240921 c.1059C>G synonymous_variant 0.48 ethambutol
embC 4240924 c.1062C>G synonymous_variant 0.49 ethambutol
embC 4240936 c.1074A>G synonymous_variant 0.49 ethambutol
embC 4240945 c.1083T>G synonymous_variant 0.47 ethambutol
embC 4240954 p.Ile364Met missense_variant 0.43 ethambutol
embC 4240960 c.1098G>C synonymous_variant 0.42 ethambutol
embC 4240966 c.1104G>C synonymous_variant 0.43 ethambutol
embC 4240969 c.1107C>T synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embC 4240972 c.1110C>G synonymous_variant 0.4 ethambutol
embC 4240979 p.Thr373Gln missense_variant 0.4 ethambutol
embC 4240983 p.Ser374Asn missense_variant 0.4 ethambutol
embC 4240987 c.1125G>C synonymous_variant 0.41 ethambutol
embC 4240990 c.1128A>G synonymous_variant 0.42 ethambutol
embC 4240996 c.1134G>C synonymous_variant 0.43 ethambutol
embC 4241002 c.1140G>C synonymous_variant 0.45 ethambutol
embC 4241013 p.Met384Thr missense_variant 0.44 ethambutol
embC 4241017 c.1155T>C synonymous_variant 0.46 ethambutol
embC 4241023 c.1161T>G synonymous_variant 0.5 ethambutol
embC 4241032 c.1170G>C synonymous_variant 0.57 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.57 ethambutol
embC 4241047 c.1185C>G synonymous_variant 0.49 ethambutol
embC 4241050 c.1188T>G synonymous_variant 0.48 ethambutol
embC 4241053 c.1191G>C synonymous_variant 0.48 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.42 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.38 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.38 ethambutol
embC 4241140 c.1278A>G synonymous_variant 0.37 ethambutol Not assoc w R - Interim
embC 4241146 c.1284C>G synonymous_variant 0.36 ethambutol
embC 4241158 c.1296T>C synonymous_variant 0.3 ethambutol
embC 4241161 c.1299C>G synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 0.29 ethambutol
embC 4241170 c.1308G>C synonymous_variant 0.32 ethambutol
embC 4241173 c.1311C>T synonymous_variant 0.33 ethambutol
embC 4241449 c.1587C>G synonymous_variant 0.25 ethambutol
embC 4241453 p.Ile531Val missense_variant 0.25 ethambutol
embC 4241479 c.1617C>G synonymous_variant 0.3 ethambutol
embC 4241480 c.1618T>C synonymous_variant 0.31 ethambutol
embC 4241488 c.1626G>C synonymous_variant 0.32 ethambutol
embC 4241496 p.Ala545Gly missense_variant 0.33 ethambutol
embC 4241500 c.1638A>C synonymous_variant 0.32 ethambutol
embC 4241501 p.Ser547Thr missense_variant 0.32 ethambutol
embC 4241506 c.1644G>C synonymous_variant 0.37 ethambutol
embC 4241518 c.1656A>G synonymous_variant 0.38 ethambutol
embC 4241521 c.1659T>C synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embC 4241530 c.1668C>A synonymous_variant 0.4 ethambutol
embC 4241536 c.1674A>G synonymous_variant 0.39 ethambutol
embC 4241539 c.1677T>C synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embC 4241545 c.1683T>C synonymous_variant 0.43 ethambutol
embC 4241548 c.1686T>C synonymous_variant 0.43 ethambutol
embC 4241551 c.1689A>G synonymous_variant 0.43 ethambutol
embC 4241567 p.Ile569Val missense_variant 0.56 ethambutol
embC 4241572 c.1710C>G synonymous_variant 0.55 ethambutol
embC 4241578 c.1716G>C synonymous_variant 0.53 ethambutol
embC 4241584 c.1722T>C synonymous_variant 0.52 ethambutol
embC 4241587 c.1725C>G synonymous_variant 0.51 ethambutol
embC 4241591 p.Leu577Val missense_variant 0.53 ethambutol
embC 4241611 c.1749G>C synonymous_variant 0.56 ethambutol
embC 4241614 c.1752A>C synonymous_variant 0.55 ethambutol
embC 4241626 c.1764T>C synonymous_variant 0.51 ethambutol
embC 4241635 c.1773G>C synonymous_variant 0.48 ethambutol
embC 4241644 c.1782G>C synonymous_variant 0.42 ethambutol
embC 4241648 c.1786_1788delTTGinsCC frameshift_variant&missense_variant 0.42 ethambutol
embC 4241657 p.Ser599Pro missense_variant 0.45 ethambutol
embC 4241665 c.1803G>C synonymous_variant 0.42 ethambutol
embC 4241671 c.1809T>C synonymous_variant 0.42 ethambutol Not assoc w R - Interim
embC 4241689 c.1827G>C synonymous_variant 0.4 ethambutol
embC 4241691 p.Gly610Ala missense_variant 0.38 ethambutol Uncertain significance
embC 4241694 p.Ala611Val missense_variant 0.37 ethambutol
embC 4241698 c.1836G>C synonymous_variant 0.38 ethambutol
embC 4241704 c.1842C>G synonymous_variant 0.36 ethambutol
embC 4241707 c.1845G>A synonymous_variant 0.36 ethambutol
embC 4241713 c.1851G>C synonymous_variant 0.39 ethambutol
embC 4241719 c.1857G>C synonymous_variant 0.39 ethambutol
embC 4241727 p.Phe622Tyr missense_variant 0.44 ethambutol
embC 4241741 c.1879_1881delGTCinsCG frameshift_variant&missense_variant 0.4 ethambutol
embC 4241747 p.Val629Leu missense_variant 0.38 ethambutol
embC 4241750 p.Leu630Val missense_variant 0.36 ethambutol
embC 4241755 c.1893C>G synonymous_variant 0.36 ethambutol
embC 4241770 c.1908T>C synonymous_variant 0.37 ethambutol Not assoc w R - Interim
embC 4241791 c.1929G>C synonymous_variant 0.33 ethambutol
embC 4241794 c.1932C>G synonymous_variant 0.31 ethambutol
embC 4241797 c.1935C>T synonymous_variant 0.31 ethambutol
embC 4242643 c.2781C>T synonymous_variant 0.93 ethambutol Not assoc w R
embA 4242742 c.-491C>G upstream_gene_variant 0.25 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 0.25 ethambutol
embA 4242754 c.-479G>C upstream_gene_variant 0.24 ethambutol
embC 4242764 p.Val968Leu missense_variant 0.27 ethambutol
embC 4242779 p.Asn973Asp missense_variant 0.25 ethambutol
embC 4242791 c.2929_2931delGCAinsTC frameshift_variant&missense_variant 0.25 ethambutol
embA 4242796 c.-437G>C upstream_gene_variant 0.24 ethambutol
embA 4242799 c.-434T>C upstream_gene_variant 0.26 ethambutol
embC 4242803 p.Val981Leu missense_variant 0.75 ethambutol Not assoc w R
embA 4242820 c.-413G>C upstream_gene_variant 0.23 ethambutol
embA 4242823 c.-410G>C upstream_gene_variant 0.23 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 0.23 ethambutol
embC 4242841 c.2979C>T synonymous_variant 0.2 ethambutol Not assoc w R - Interim
embA 4244366 c.1134C>G synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embA 4244372 c.1140T>G synonymous_variant 0.27 ethambutol
embA 4244378 c.1146G>A synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embA 4244462 c.1230A>G synonymous_variant 0.24 ethambutol
embA 4244498 c.1266A>G synonymous_variant 0.32 ethambutol
embA 4244507 c.1275G>T synonymous_variant 0.3 ethambutol Not assoc w R - Interim
embA 4244508 c.1276T>C synonymous_variant 0.3 ethambutol
embA 4244516 c.1284G>C synonymous_variant 0.29 ethambutol
embA 4244517 p.Leu429Val missense_variant 0.29 ethambutol
embA 4244523 p.Pro431Ala missense_variant 0.32 ethambutol
embA 4244534 c.1302T>C synonymous_variant 0.27 ethambutol
embA 4244537 c.1305T>G synonymous_variant 0.27 ethambutol
embA 4244543 c.1311C>G synonymous_variant 0.27 ethambutol
embA 4244547 p.Ile439Val missense_variant 0.29 ethambutol
embA 4244552 c.1320C>G synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embA 4244557 p.Arg442Thr missense_variant 0.31 ethambutol
embA 4244567 c.1335C>T synonymous_variant 0.32 ethambutol
embA 4244582 c.1350T>C synonymous_variant 0.3 ethambutol
embA 4244885 c.1653A>G synonymous_variant 0.27 ethambutol
embA 4244897 c.1665T>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embA 4244900 c.1668G>C synonymous_variant 0.23 ethambutol
embA 4244904 p.Val558Ile missense_variant 0.26 ethambutol
embA 4244918 c.1686G>C synonymous_variant 0.26 ethambutol
embA 4244919 p.Leu563Val missense_variant 0.26 ethambutol
embA 4244930 c.1698G>C synonymous_variant 0.27 ethambutol
embA 4244933 c.1701A>G synonymous_variant 0.26 ethambutol
embA 4244936 c.1704C>G synonymous_variant 0.25 ethambutol
embA 4244945 c.1713C>G synonymous_variant 0.25 ethambutol
embA 4244946 c.1714_1716delGTGinsAC frameshift_variant&missense_variant 0.25 ethambutol Uncertain significance
embA 4244957 c.1725C>T synonymous_variant 0.25 ethambutol
embA 4244960 c.1728A>C synonymous_variant 0.25 ethambutol
embA 4244966 c.1734C>G synonymous_variant 0.25 ethambutol
embA 4244969 c.1737G>A synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embA 4244980 p.Val583Ala missense_variant 0.25 ethambutol
embA 4244982 c.1750T>C synonymous_variant 0.25 ethambutol
embA 4244987 c.1755T>C synonymous_variant 0.25 ethambutol
embA 4245003 p.Thr591Ala missense_variant 0.25 ethambutol Uncertain significance
embA 4245005 c.1775_1776delTT frameshift_variant 0.26 ethambutol Uncertain significance
embA 4245011 c.1779C>T synonymous_variant 0.25 ethambutol
embA 4245014 c.1782_1783insGG frameshift_variant 0.25 ethambutol Uncertain significance
embA 4245020 c.1788T>C synonymous_variant 0.24 ethambutol
embA 4245023 c.1791A>G synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embA 4245026 c.1794T>C synonymous_variant 0.23 ethambutol
embA 4245028 p.Ser599Asn missense_variant 0.25 ethambutol
embA 4245032 c.1800A>C synonymous_variant 0.28 ethambutol
embA 4245041 c.1809C>G synonymous_variant 0.3 ethambutol
embA 4245044 c.1812G>C synonymous_variant 0.36 ethambutol
embA 4245053 c.1821G>C synonymous_variant 0.42 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.43 ethambutol
embA 4245083 c.1851A>C synonymous_variant 0.5 ethambutol
embA 4245089 c.1857G>C synonymous_variant 0.45 ethambutol
embA 4245092 c.1860C>G synonymous_variant 0.46 ethambutol
embA 4245101 c.1869G>C synonymous_variant 0.47 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.5 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.45 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.44 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.46 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.51 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.52 ethambutol
embA 4245198 p.Leu656Ile missense_variant 0.51 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.5 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.48 ethambutol
embA 4245222 c.1990_1992delTATinsCG frameshift_variant&missense_variant 0.47 ethambutol Uncertain significance
embA 4245248 c.2016G>C synonymous_variant 0.43 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.41 ethambutol
embA 4245263 c.2031A>G synonymous_variant 0.39 ethambutol Not assoc w R - Interim
embA 4245282 p.Ile684Val missense_variant 0.35 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.35 ethambutol
embA 4245290 c.2058C>G synonymous_variant 0.35 ethambutol
embA 4245293 c.2061T>G synonymous_variant 0.33 ethambutol
embA 4245296 c.2064G>C synonymous_variant 0.33 ethambutol
embA 4245299 c.2067A>G synonymous_variant 0.33 ethambutol
embA 4245315 p.Val695Thr missense_variant 0.32 ethambutol
embA 4245328 p.Ala699Val missense_variant 0.31 ethambutol
embA 4245335 c.2103A>G synonymous_variant 0.31 ethambutol
embA 4245340 p.Gly703Ala missense_variant 0.31 ethambutol
embA 4245345 p.Met705Leu missense_variant 0.31 ethambutol
embA 4245348 p.Ala706Thr missense_variant 0.3 ethambutol
embA 4245355 p.Ala708Gly missense_variant 0.31 ethambutol
embA 4245368 c.2136T>C synonymous_variant 0.3 ethambutol
embA 4245377 c.2145T>C synonymous_variant 0.24 ethambutol
embA 4245572 c.2340C>T synonymous_variant 0.21 ethambutol Not assoc w R - Interim
embB 4245575 c.-939C>G upstream_gene_variant 0.21 ethambutol
embA 4245576 p.Lys782Gln missense_variant 0.21 ethambutol
embA 4245643 p.Ala804Val missense_variant 0.21 ethambutol
embA 4245648 p.Ile806Tyr missense_variant 0.21 ethambutol
embB 4245668 c.-846C>G upstream_gene_variant 0.23 ethambutol
embA 4245674 c.2442A>C synonymous_variant 0.23 ethambutol Not assoc w R - Interim
embB 4245677 c.-837G>C upstream_gene_variant 0.25 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.31 ethambutol
embB 4245701 c.-813G>C upstream_gene_variant 0.28 ethambutol
embB 4245704 c.-810G>C upstream_gene_variant 0.28 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 0.24 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.24 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.24 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.23 ethambutol
embB 4245833 c.-681G>C upstream_gene_variant 0.26 ethambutol
embB 4245842 c.-672G>C upstream_gene_variant 0.28 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 0.3 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.36 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.35 ethambutol
embA 4245885 p.Asp885Thr missense_variant 0.32 ethambutol
embA 4245892 p.Ile887Thr missense_variant 0.33 ethambutol Uncertain significance
embA 4245899 c.2667C>G synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embB 4245902 c.-612G>A upstream_gene_variant 0.32 ethambutol
embB 4245905 c.-609C>G upstream_gene_variant 0.31 ethambutol
embB 4245911 c.-603A>G upstream_gene_variant 0.31 ethambutol
embB 4245917 c.-597G>A upstream_gene_variant 0.3 ethambutol
embA 4245930 p.Gly900Arg missense_variant 0.29 ethambutol
embA 4245942 p.Arg904Thr missense_variant 0.26 ethambutol
embA 4245946 p.Ile905Thr missense_variant 0.26 ethambutol
embB 4245953 c.-561A>G upstream_gene_variant 0.25 ethambutol
embA 4245958 p.Gly909Ala missense_variant 0.24 ethambutol
embA 4245960 p.Gln910Glu missense_variant 0.24 ethambutol
embA 4245965 c.2733A>G synonymous_variant 0.24 ethambutol Not assoc w R - Interim
embA 4245966 p.Phe912Gln missense_variant 0.24 ethambutol
embB 4245983 c.-531A>C upstream_gene_variant 0.24 ethambutol
embB 4245989 c.-525A>G upstream_gene_variant 0.24 ethambutol
embB 4245992 c.-522C>G upstream_gene_variant 0.24 ethambutol
embB 4246004 c.-510T>C upstream_gene_variant 0.27 ethambutol
embB 4246010 c.-504G>T upstream_gene_variant 0.25 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 0.3 ethambutol
embB 4246022 c.-492C>G upstream_gene_variant 0.3 ethambutol
embB 4246040 c.-474C>G upstream_gene_variant 0.33 ethambutol
embA 4246041 p.Asp937Asn missense_variant 0.37 ethambutol
embA 4246055 c.2823T>C synonymous_variant 0.38 ethambutol Not assoc w R - Interim
embB 4246064 c.-450T>C upstream_gene_variant 0.43 ethambutol
embA 4246080 c.2848_2850delCCTinsTC frameshift_variant&missense_variant 0.39 ethambutol Uncertain significance
embA 4246088 c.2856A>G synonymous_variant 0.37 ethambutol Not assoc w R
embB 4246097 c.-417C>G upstream_gene_variant 0.35 ethambutol
embA 4246103 c.2871C>G synonymous_variant 0.33 ethambutol Not assoc w R - Interim
embB 4246109 c.-405C>G upstream_gene_variant 0.33 ethambutol
embB 4246115 c.-399T>G upstream_gene_variant 0.33 ethambutol
embA 4246128 c.2896_2898delTCTinsAC frameshift_variant&missense_variant 0.33 ethambutol Uncertain significance
embA 4246138 p.Arg969Gln missense_variant 0.32 ethambutol
embB 4246140 c.-374T>C upstream_gene_variant 0.31 ethambutol
embA 4246143 p.Ile971Val missense_variant 0.33 ethambutol
embA 4246151 c.2919A>G synonymous_variant 0.29 ethambutol Not assoc w R - Interim
embA 4246152 p.Ala974Gln missense_variant 0.29 ethambutol
embB 4246157 c.-357A>G upstream_gene_variant 0.29 ethambutol
embA 4246164 c.2932T>C synonymous_variant 0.35 ethambutol Not assoc w R - Interim
embB 4246184 c.-330A>C upstream_gene_variant 0.4 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 0.37 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 0.36 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 0.36 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 0.34 ethambutol
embA 4246220 c.2988T>C synonymous_variant 0.32 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 0.32 ethambutol
embA 4246227 p.Ile999Val missense_variant 0.33 ethambutol
embA 4246235 c.3003G>A synonymous_variant 0.34 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 0.33 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.32 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.33 ethambutol
embA 4246264 p.His1011Arg missense_variant 0.28 ethambutol
embB 4247389 c.876C>G synonymous_variant 0.24 ethambutol
embB 4247395 c.882C>G synonymous_variant 0.27 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.27 ethambutol
embB 4247407 c.894G>C synonymous_variant 0.3 ethambutol
embB 4247413 c.900C>T synonymous_variant 0.33 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.35 ethambutol
embB 4247434 c.921C>G synonymous_variant 0.37 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.37 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.38 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.38 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.38 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.4 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.41 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.43 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.44 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.45 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.44 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.46 ethambutol
embB 4247572 c.1059A>G synonymous_variant 0.45 ethambutol
embB 4247579 p.Ala356Phe missense_variant 0.42 ethambutol
embB 4247587 c.1074G>A synonymous_variant 0.41 ethambutol
embB 4247588 c.1075_1077delCTAinsAC frameshift_variant&missense_variant 0.41 ethambutol
embB 4247603 c.1090C>T synonymous_variant 0.42 ethambutol
embB 4247611 c.1098G>T synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4247614 c.1101T>C synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.43 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.43 ethambutol
embB 4247638 c.1125G>C synonymous_variant 0.44 ethambutol
embB 4247646 p.Glu378Ala missense_variant 0.41 ethambutol Not assoc w R
embB 4247656 c.1143A>G synonymous_variant 0.44 ethambutol
embB 4247659 c.1146C>G synonymous_variant 0.44 ethambutol
embB 4247662 c.1149C>G synonymous_variant 0.44 ethambutol
embB 4247683 c.1170C>G synonymous_variant 0.49 ethambutol
embB 4247692 c.1179C>G synonymous_variant 0.49 ethambutol
embB 4247716 c.1203C>T synonymous_variant 0.45 ethambutol
embB 4247722 c.1209G>T synonymous_variant 0.45 ethambutol
embB 4247725 c.1212G>C synonymous_variant 0.45 ethambutol
embB 4247729 p.Gly406Pro missense_variant 0.44 ethambutol
embB 4247746 c.1233C>T synonymous_variant 0.47 ethambutol
embB 4247761 c.1248T>C synonymous_variant 0.43 ethambutol
embB 4247773 c.1260G>A synonymous_variant 0.43 ethambutol
embB 4247776 c.1263G>T synonymous_variant 0.42 ethambutol
embB 4247797 c.1284C>G synonymous_variant 0.45 ethambutol
embB 4247800 c.1287A>T synonymous_variant 0.45 ethambutol
embB 4247803 c.1290G>C synonymous_variant 0.45 ethambutol
embB 4247815 c.1302C>G synonymous_variant 0.44 ethambutol
embB 4247819 c.1306_1308delGTTinsAC frameshift_variant&missense_variant 0.45 ethambutol
embB 4247830 c.1317A>G synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embB 4247836 c.1323A>G synonymous_variant 0.46 ethambutol Not assoc w R - Interim
embB 4247839 c.1326G>C synonymous_variant 0.44 ethambutol Not assoc w R - Interim
embB 4247866 c.1353G>C synonymous_variant 0.48 ethambutol
embB 4247875 c.1362G>C synonymous_variant 0.46 ethambutol
embB 4247876 c.1363C>T synonymous_variant 0.46 ethambutol
embB 4247881 c.1368G>C synonymous_variant 0.45 ethambutol
embB 4247887 c.1374C>T synonymous_variant 0.45 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.47 ethambutol
embB 4247899 p.Met462Ile missense_variant 0.47 ethambutol
embB 4247905 c.1392G>C synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 0.49 ethambutol
embB 4247932 c.1419C>G synonymous_variant 0.44 ethambutol
embB 4247940 p.Leu476Trp missense_variant 0.45 ethambutol
embB 4247945 c.1432T>C synonymous_variant 0.45 ethambutol
embB 4247951 p.Ser480Ala missense_variant 0.47 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4247974 c.1461C>G synonymous_variant 0.48 ethambutol
embB 4248007 c.1494C>G synonymous_variant 0.36 ethambutol
embB 4248011 p.Ser500Arg missense_variant 0.38 ethambutol
embB 4248014 p.Thr501Ala missense_variant 0.38 ethambutol Uncertain significance
embB 4248035 p.Val508Ile missense_variant 0.41 ethambutol
embB 4248040 c.1527C>G synonymous_variant 0.44 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.44 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.44 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.49 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.53 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.52 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.5 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.5 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.49 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.49 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.49 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4248199 c.1686A>G synonymous_variant 0.47 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.47 ethambutol
embB 4248205 c.1692C>G synonymous_variant 0.49 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.5 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.5 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.51 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.52 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.5 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.46 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.43 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.39 ethambutol
embB 4248361 c.1848A>C synonymous_variant 0.39 ethambutol
embB 4248362 p.Ser617Ala missense_variant 0.39 ethambutol
embB 4248373 c.1860C>G synonymous_variant 0.39 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.37 ethambutol
embB 4248407 p.Leu632Val missense_variant 0.31 ethambutol
embB 4248410 c.1897_1899delTTCinsCG frameshift_variant&missense_variant 0.3 ethambutol
embB 4248419 p.Leu636Met missense_variant 0.28 ethambutol
embB 4248425 c.1912T>C synonymous_variant 0.28 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 0.27 ethambutol
embB 4248432 p.Trp640Phe missense_variant 0.27 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.26 ethambutol
embB 4249312 c.2799C>T synonymous_variant 0.24 ethambutol
embB 4249369 c.2856T>C synonymous_variant 0.27 ethambutol
embB 4249375 c.2862G>C synonymous_variant 0.29 ethambutol
embB 4249381 c.2868A>G synonymous_variant 0.32 ethambutol
embB 4249384 c.2871G>T synonymous_variant 0.31 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.29 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.25 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.25 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.23 ethambutol
embB 4249441 c.2928A>G synonymous_variant 0.25 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 0.25 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.34 ethambutol
embB 4249486 c.2973T>G synonymous_variant 0.41 ethambutol
embB 4249498 c.2985G>C synonymous_variant 0.39 ethambutol
embB 4249521 p.Ala1003Val missense_variant 0.31 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.31 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.32 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.31 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.31 ethambutol
embB 4249543 c.3030G>C synonymous_variant 0.31 ethambutol
embB 4249546 c.3033G>A synonymous_variant 0.31 ethambutol
embB 4249558 c.3045A>C synonymous_variant 0.3 ethambutol
embB 4249568 p.Ser1019Thr missense_variant 0.28 ethambutol
embB 4249573 c.3060T>C synonymous_variant 0.26 ethambutol
embB 4249580 p.Leu1023Met missense_variant 0.28 ethambutol
embB 4249594 c.3081G>C synonymous_variant 0.26 ethambutol
embB 4249606 c.3093C>A synonymous_variant 0.27 ethambutol
embB 4249609 c.3096T>C synonymous_variant 0.25 ethambutol
embB 4249615 c.3102C>G synonymous_variant 0.23 ethambutol
embB 4249618 c.3105C>G synonymous_variant 0.23 ethambutol
embB 4249624 c.3111C>G synonymous_variant 0.23 ethambutol
embB 4249627 c.3114G>C synonymous_variant 0.21 ethambutol
aftB 4268096 c.741C>G synonymous_variant 0.29 ethambutol
aftB 4268099 c.738G>C synonymous_variant 0.29 ethambutol
aftB 4268102 c.735C>G synonymous_variant 0.29 ethambutol Not assoc w R - Interim
aftB 4268117 c.720G>C synonymous_variant 0.24 ethambutol
aftB 4268164 p.Gln225Glu missense_variant 0.24 ethambutol
aftB 4268169 p.Ala223Gly missense_variant 0.24 ethambutol
aftB 4268171 c.666G>C synonymous_variant 0.24 ethambutol
aftB 4268194 p.Leu215Val missense_variant 0.23 ethambutol
aftB 4268205 p.Val211Ala missense_variant 0.24 ethambutol
aftB 4268213 c.624T>G synonymous_variant 0.23 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.25 ethambutol
aftB 4268994 c.-158T>G upstream_gene_variant 0.2 ethambutol
ubiA 4268999 c.835C>T synonymous_variant 0.2 ethambutol Not assoc w R - Interim
aftB 4269006 c.-170T>C upstream_gene_variant 0.22 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 0.22 ethambutol
ubiA 4269027 c.807C>T synonymous_variant 0.22 ethambutol Not assoc w R - Interim
aftB 4269033 c.-197T>C upstream_gene_variant 0.21 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 0.22 ethambutol
ubiA 4269075 c.757_759delATTinsGC frameshift_variant&missense_variant 0.3 ethambutol
aftB 4269081 c.-245G>C upstream_gene_variant 0.31 ethambutol
aftB 4269084 c.-248G>C upstream_gene_variant 0.31 ethambutol
ubiA 4269102 c.731_732delGCinsCCATTCG frameshift_variant&missense_variant 0.3 ethambutol
ubiA 4269105 c.724_728delGGCTA frameshift_variant 0.3 ethambutol
aftB 4269123 c.-287T>G upstream_gene_variant 0.31 ethambutol
ubiA 4269131 c.703C>T synonymous_variant 0.3 ethambutol Not assoc w R - Interim
aftB 4269132 c.-296G>C upstream_gene_variant 0.3 ethambutol
aftB 4269138 c.-302C>T upstream_gene_variant 0.3 ethambutol
ubiA 4269141 c.691_693delTTGinsGC frameshift_variant&missense_variant 0.31 ethambutol
ubiA 4269144 c.690C>G synonymous_variant 0.31 ethambutol Not assoc w R - Interim
aftB 4269159 c.-323G>C upstream_gene_variant 0.35 ethambutol
ubiA 4269164 p.Leu224Met missense_variant 0.35 ethambutol
aftB 4269165 c.-329G>C upstream_gene_variant 0.35 ethambutol
aftB 4269179 c.-343C>A upstream_gene_variant 0.4 ethambutol
aftB 4269183 c.-347T>C upstream_gene_variant 0.43 ethambutol
aftB 4269186 c.-350C>G upstream_gene_variant 0.43 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 0.47 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 0.42 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 0.42 ethambutol Not assoc w R - Interim
aftB 4269234 c.-398A>G upstream_gene_variant 0.41 ethambutol
aftB 4269242 c.-406C>T upstream_gene_variant 0.42 ethambutol
ubiA 4269243 p.His197Gln missense_variant 0.44 ethambutol
aftB 4269249 c.-413G>A upstream_gene_variant 0.44 ethambutol
aftB 4269342 c.-506G>C upstream_gene_variant 0.51 ethambutol
ubiA 4269357 c.475_477delATCinsCG frameshift_variant&missense_variant 0.5 ethambutol
aftB 4269362 c.-526T>C upstream_gene_variant 0.52 ethambutol
aftB 4269363 c.-527T>C upstream_gene_variant 0.51 ethambutol
aftB 4269372 c.-536G>A upstream_gene_variant 0.51 ethambutol
ubiA 4269380 p.Val152Ile missense_variant 0.5 ethambutol
ubiA 4269387 p.Glu149Asp missense_variant 0.49 ethambutol Not assoc w R
ubiA 4269390 c.442_444delGTGinsCT frameshift_variant&missense_variant 0.46 ethambutol
aftB 4269402 c.-566T>C upstream_gene_variant 0.44 ethambutol
aftB 4269405 c.-569G>A upstream_gene_variant 0.43 ethambutol
aftB 4269411 c.-575T>A upstream_gene_variant 0.4 ethambutol
aftB 4269414 c.-578T>C upstream_gene_variant 0.39 ethambutol
aftB 4269420 c.-584T>C upstream_gene_variant 0.4 ethambutol
aftB 4269428 c.-592T>C upstream_gene_variant 0.36 ethambutol
ubiA 4269436 p.Ala133Gly missense_variant 0.37 ethambutol
ubiA 4269448 p.Val129Ala missense_variant 0.29 ethambutol
aftB 4269453 c.-617A>G upstream_gene_variant 0.25 ethambutol
aftB 4269458 c.-622C>T upstream_gene_variant 0.22 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin