TB-Profiler result

Run: ERR1063896

Summary

Run ID: ERR1063896

Sample name:

Date: 2024-05-22T11:38:01.321987

Number of reads: 388274

Percentage reads mapped: 11.91

Median coverage: 4.0

Strain:

Spoligotype:

Drug-resistance: HR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.346_348delCACinsGG Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.508_510delGTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.766_768delGCTinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.2074_2076delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2077_2079delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491290 c.508_510delGTGinsAC frameshift_variant&missense_variant 0.89 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.93 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491548 c.766_768delGCTinsCC frameshift_variant&missense_variant 0.91 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 0.93 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305004 c.2074_2076delGAAinsAC frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305007 c.2077_2079delATCinsGG frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155764 c.346_348delCACinsGG frameshift_variant&missense_variant 0.64 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6100 c.861G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6109 c.870G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.9 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6175 c.936G>A synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6181 c.942C>A synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 6601 c.-701A>G upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 6607 c.-695T>C upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>A upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6685 c.-617C>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6728 c.1489_1491delCTAinsTG frameshift_variant&stop_gained 0.97 levofloxacin Uncertain significance
moxifloxacin
gyrA 6751 c.-551G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.95 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.92 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6838 c.-464C>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6872 c.1633_1635delTTGinsCC frameshift_variant&missense_variant 0.73 levofloxacin Uncertain significance
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6896 p.Arg553Lys missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7135 c.-167G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 7159 c.1920C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7162 c.1923C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 0.84 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7216 c.-86G>A upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8191 p.Ala297Gly missense_variant 0.72 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8198 c.897T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8240 c.939C>A synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8246 c.945C>G synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8247 c.946_948delATCinsGG frameshift_variant&missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.79 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8357 c.1056G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8456 c.1155C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8477 c.1176C>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.81 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>A synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.72 levofloxacin
moxifloxacin
gyrA 8799 p.Ala500Pro missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8813 p.Asp504Glu missense_variant 0.75 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8816 c.1515C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8840 c.1539C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9323 c.2022C>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 c.2023_2025delTCGinsAGC synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCC frameshift_variant&missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9641 c.2340C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9662 c.2361G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9683 c.2382G>T synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9707 c.2406G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9738 c.2437_2439delTTGinsAT frameshift_variant&missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 9743 c.2442C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9746 c.2445C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
fgd1 491232 c.450T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491248 p.Arg156Lys missense_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491255 p.Lys158Arg missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491271 c.489C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491313 c.531C>T synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491321 p.Ala180Val missense_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491346 c.564C>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 0.31 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491352 c.570C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491355 c.573C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491370 c.588C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491379 c.597C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491481 c.699C>T synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491490 c.708C>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491493 c.711C>T synonymous_variant 0.43 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491536 c.754C>T synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491562 c.780C>T synonymous_variant 0.47 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491571 c.789C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491604 c.822G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491655 c.873C>T synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491661 c.879C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491688 c.906A>G synonymous_variant 0.91 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.69 ethionamide
isoniazid
mshA 575692 c.345G>A synonymous_variant 0.64 ethionamide
isoniazid
mshA 575704 c.357T>C synonymous_variant 0.88 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575725 c.378C>G synonymous_variant 0.88 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.94 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>A synonymous_variant 0.86 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 0.83 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 0.93 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 0.83 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.81 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.82 ethionamide
isoniazid Not assoc w R - Interim
mshA 575821 c.474G>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.72 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.87 ethionamide
isoniazid
ccsA 620619 c.729G>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 0.9 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620764 c.874_876delGCCinsTG frameshift_variant&missense_variant 0.77 capreomycin
amikacin
kanamycin
hadA 731753 c.-177A>G upstream_gene_variant 0.79 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.77 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.77 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.75 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.75 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.75 isoniazid
hadA 731823 c.-107_-105delCTGinsAC upstream_gene_variant 0.75 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.43 isoniazid
hadA 732241 c.312C>T synonymous_variant 0.47 isoniazid
hadA 732250 c.321C>G synonymous_variant 0.5 isoniazid
hadA 732257 p.Asp110His missense_variant 0.5 isoniazid
hadA 732262 c.333G>C synonymous_variant 0.5 isoniazid
hadA 732265 c.336G>A synonymous_variant 0.5 isoniazid Not assoc w R - Interim
hadA 732268 c.339T>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
hadA 732269 p.Glu114Lys missense_variant 0.54 isoniazid
hadA 732284 c.355_357delCAGinsGC frameshift_variant&missense_variant 0.5 isoniazid Uncertain significance
hadA 732308 p.Val127Ile missense_variant 0.54 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.58 isoniazid
hadA 732319 p.Glu130Asp missense_variant 0.58 isoniazid
hadA 732320 p.Glu131Lys missense_variant 0.58 isoniazid
hadA 732329 c.400_402delCTCinsGG frameshift_variant&missense_variant 0.58 isoniazid Uncertain significance
hadA 732334 c.405G>C synonymous_variant 0.64 isoniazid
hadA 732341 p.Thr138Ala missense_variant 0.64 isoniazid
nusG 734403 c.150C>T synonymous_variant 0.8 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.87 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.91 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.91 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.9 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.92 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.92 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.93 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.96 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.82 rifampicin
rpoB 760082 c.276C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 0.75 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.69 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.81 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.84 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 0.81 rifampicin
rpoB 760139 c.333A>T synonymous_variant 0.81 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.82 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.99 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.98 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.99 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.98 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.98 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.97 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.96 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.86 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.78 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.77 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 0.67 rifampicin
rpoB 760567 c.761_762delCGinsGGGC frameshift_variant&missense_variant 0.67 rifampicin
rpoB 760571 c.765G>C synonymous_variant 0.65 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.67 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.78 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.73 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 0.73 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.89 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 0.91 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.88 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.85 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 0.87 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.87 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.9 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.93 rifampicin
rpoB 760784 c.978G>T synonymous_variant 0.96 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.96 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.96 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.95 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.86 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.81 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.81 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.81 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.81 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.83 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.83 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.75 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.72 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.82 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.71 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.78 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 0.78 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.9 rifampicin
rpoB 761288 c.1482G>T synonymous_variant 0.9 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.94 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.93 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.92 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.92 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.97 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.97 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.9 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.67 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>C synonymous_variant 0.76 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.94 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.96 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.97 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.91 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.96 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 0.83 rifampicin
rpoB 761785 p.Thr660Ser missense_variant 0.71 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.76 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.92 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.92 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.92 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.92 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.9 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.89 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.89 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.98 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 0.87 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.9 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.9 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.9 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 0.88 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.88 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.89 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.87 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.88 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.87 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.89 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.89 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.9 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.91 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762515 c.2709C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.89 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.88 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.88 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.88 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.85 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.82 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.71 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 0.83 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 0.83 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.76 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.86 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 0.86 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.85 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 0.72 rifampicin
rpoC 763199 c.-171G>C upstream_gene_variant 0.7 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 0.75 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.67 rifampicin
rpoC 763206 c.-164_-163delAGinsTC upstream_gene_variant 0.76 rifampicin
rpoC 763217 c.-153G>C upstream_gene_variant 0.71 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.76 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.76 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.72 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.72 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.72 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.94 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.94 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.91 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.91 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.91 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.86 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>T synonymous_variant 0.82 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763606 c.237C>T synonymous_variant 0.89 rifampicin
rpoC 763615 c.246G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.89 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.93 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.94 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.9 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.89 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.91 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.87 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.93 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.92 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.9 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.91 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.92 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.96 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.96 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.96 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.95 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.95 rifampicin
rpoC 763882 c.513G>A synonymous_variant 0.98 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.95 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.95 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.95 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.95 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.94 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.88 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.86 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.79 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.9 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.86 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.85 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.85 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.83 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.82 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.87 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.88 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.89 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.83 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.81 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.82 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.82 rifampicin
rpoC 764089 c.720C>G synonymous_variant 0.65 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.82 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.85 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.87 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.79 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 0.72 rifampicin
rpoC 764203 c.834G>C synonymous_variant 0.72 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.68 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.62 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.76 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.7 rifampicin
rpoC 764227 c.858G>T synonymous_variant 0.76 rifampicin
rpoC 764239 c.870T>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 0.78 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.88 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.8 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.88 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.82 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764297 c.928_930delATGinsCT frameshift_variant&missense_variant 0.86 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.9 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.95 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.95 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.96 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.96 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.96 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 0.89 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.99 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.94 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.96 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.94 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.94 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 0.88 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.64 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765338 p.Gln657Lys missense_variant 0.85 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765357 p.Met663Thr missense_variant 0.8 rifampicin
rpoC 765361 c.1992C>G synonymous_variant 0.88 rifampicin
rpoC 765383 c.2014_2016delATGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 0.97 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.97 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.97 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.95 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.98 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.96 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.96 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.9 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.89 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.78 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.76 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.84 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 0.74 rifampicin
rpoC 765779 c.2410_2412delGACinsAG frameshift_variant&missense_variant 0.74 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.9 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.91 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.85 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.91 rifampicin
rpoC 765814 c.2445A>C synonymous_variant 0.91 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.87 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 0.98 rifampicin
rpoC 765875 p.Val836Ile missense_variant 0.96 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.96 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.96 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.94 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.95 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.95 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.95 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 0.95 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.7 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 0.7 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.75 rifampicin
rpoC 766517 c.3148_3150delACCinsGG frameshift_variant&missense_variant 0.75 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.75 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 0.82 rifampicin
rpoC 766554 p.Tyr1062Phe missense_variant 0.64 rifampicin
rpoC 766658 c.3289_3291delCGGinsGC frameshift_variant&missense_variant 0.75 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.75 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.77 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 0.79 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 0.88 rifampicin
rpoC 766694 c.3325_3327delCAGinsGC frameshift_variant&missense_variant 0.82 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.85 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 0.81 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.86 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.96 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.97 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.97 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.97 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.97 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.97 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 0.75 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 0.78 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 766981 c.3612T>C synonymous_variant 0.9 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.87 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.83 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.85 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.91 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.94 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.83 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
mmpL5 775814 c.2667C>G synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 775817 c.2664T>C synonymous_variant 0.79 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775829 c.2652C>G synonymous_variant 0.84 clofazimine
bedaquiline
mmpL5 775838 c.2643G>C synonymous_variant 0.44 clofazimine
bedaquiline
mmpL5 775851 p.Ser877Thr missense_variant 0.45 clofazimine
bedaquiline
mmpL5 775853 c.2628C>T synonymous_variant 0.42 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775877 c.2604C>G synonymous_variant 0.56 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsTG frameshift_variant&missense_variant 0.56 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775892 c.2589C>T synonymous_variant 0.4 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.89 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.69 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 0.75 clofazimine
bedaquiline
mmpL5 775916 c.2565T>C synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.38 clofazimine
bedaquiline
mmpL5 775924 c.2557C>T synonymous_variant 0.38 clofazimine Not assoc w R - Interim
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.72 clofazimine
bedaquiline
mmpL5 775970 c.2511G>C synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.88 clofazimine
bedaquiline
mmpL5 775994 c.2485_2487delATCinsCG frameshift_variant&missense_variant 0.7 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775997 c.2484T>G synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.69 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 0.8 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 776021 c.2460G>A synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.74 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 776075 c.2406C>G synonymous_variant 0.58 clofazimine
bedaquiline
mmpL5 776081 c.2400G>C synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 776084 c.2397C>G synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 776087 c.2394C>G synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Leu missense_variant 0.77 clofazimine
bedaquiline
mmpL5 776120 c.2361C>T synonymous_variant 0.83 clofazimine
bedaquiline
rpsL 781572 c.13_15delCAGinsAC frameshift_variant&missense_variant 0.87 streptomycin Uncertain significance
rpsL 781595 c.36T>C synonymous_variant 0.92 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.92 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.89 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.89 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.93 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.93 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.93 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.94 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.95 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.96 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.97 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 0.97 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.98 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.94 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.88 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.88 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.95 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.85 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.92 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.86 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.87 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.86 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.96 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.96 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.96 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.96 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.93 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.92 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.93 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.92 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.92 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.87 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.96 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.96 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.95 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.97 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.97 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.96 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.96 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.93 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.94 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.94 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.94 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.92 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.92 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.91 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.92 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.85 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.85 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.86 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.8 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.83 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.85 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.85 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.85 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.82 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.82 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.8 linezolid
rplC 800873 p.Arg22Lys missense_variant 0.91 linezolid
rplC 800877 c.69A>C synonymous_variant 0.92 linezolid
rplC 800880 c.72A>C synonymous_variant 0.92 linezolid
rplC 800889 c.81C>G synonymous_variant 0.93 linezolid
rplC 800892 c.84G>C synonymous_variant 0.93 linezolid
rplC 800895 c.87C>G synonymous_variant 0.93 linezolid
rplC 800904 c.96G>C synonymous_variant 0.93 linezolid
rplC 800916 c.108A>G synonymous_variant 0.94 linezolid
rplC 800921 p.Arg38Leu missense_variant 0.94 linezolid
rplC 800928 c.120C>T synonymous_variant 0.95 linezolid
rplC 800931 c.123G>C synonymous_variant 0.95 linezolid
rplC 800937 c.129A>G synonymous_variant 0.96 linezolid
rplC 800946 c.138T>C synonymous_variant 0.96 linezolid
rplC 800949 c.141T>C synonymous_variant 0.97 linezolid
rplC 800964 c.156G>C synonymous_variant 0.95 linezolid
rplC 800985 c.177A>G synonymous_variant 0.91 linezolid
rplC 801003 c.195G>C synonymous_variant 0.88 linezolid
rplC 801004 c.196_198delCTGinsGC frameshift_variant&missense_variant 0.88 linezolid
rplC 801009 c.201A>C synonymous_variant 0.88 linezolid
rplC 801012 c.204T>C synonymous_variant 0.88 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.88 linezolid
rplC 801027 c.219C>G synonymous_variant 0.88 linezolid
rplC 801039 c.231A>G synonymous_variant 0.85 linezolid
rplC 801045 c.237A>C synonymous_variant 0.83 linezolid
rplC 801046 p.Tyr80His missense_variant 0.83 linezolid
rplC 801054 c.246G>C synonymous_variant 0.64 linezolid
rplC 801171 c.363A>G synonymous_variant 0.67 linezolid
rplC 801174 c.366T>C synonymous_variant 0.64 linezolid
rplC 801195 c.387G>T synonymous_variant 0.89 linezolid
rplC 801205 p.Arg133Ala missense_variant 0.85 linezolid
rplC 801210 c.402T>C synonymous_variant 0.95 linezolid
rplC 801220 p.Ser138Ala missense_variant 0.87 linezolid
rplC 801231 c.423C>T synonymous_variant 0.95 linezolid
rplC 801237 c.429G>A synonymous_variant 0.91 linezolid
rplC 801252 c.444G>C synonymous_variant 0.88 linezolid
rplC 801264 c.456C>T synonymous_variant 0.88 linezolid
rplC 801267 c.459A>C synonymous_variant 0.87 linezolid
rplC 801276 c.468G>C synonymous_variant 0.83 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.78 linezolid
rplC 801285 c.477G>C synonymous_variant 0.77 linezolid
fbiC 1303492 c.562T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303536 c.606G>A synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303548 c.618G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303554 c.624G>A synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303587 c.657G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303593 c.663G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304515 p.Ala529Thr missense_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304541 c.1611C>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>G synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305039 c.2109G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
sigE 1364650 p.Thr80Ala missense_variant 0.58 pyrazinamide Uncertain significance
sigE 1364661 c.249C>A synonymous_variant 0.69 pyrazinamide
sigE 1364667 c.255T>C synonymous_variant 0.65 pyrazinamide
sigE 1364679 c.267T>C synonymous_variant 0.67 pyrazinamide
sigE 1364682 c.270G>A synonymous_variant 0.67 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.68 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.78 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.85 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.86 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.86 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.92 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.94 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.94 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 0.92 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 0.92 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.92 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.91 pyrazinamide
sigE 1364796 c.384G>A synonymous_variant 0.95 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.95 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.9 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.95 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.86 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.96 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.93 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.93 pyrazinamide
atpE 1461132 p.Val30Ile missense_variant 0.86 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.86 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.95 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.96 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.96 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 0.96 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.96 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.93 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.93 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.93 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 0.9 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.89 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.85 bedaquiline
atpE 1461227 c.183G>A synonymous_variant 0.84 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 0.84 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.84 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 0.81 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.78 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 0.43 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.88 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 0.84 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>A non_coding_transcript_exon_variant 0.44 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.49 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.86 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474044 n.387C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474045 n.388C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474053 n.396G>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1474102 n.446_449delAGTA non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474108 n.451C>G non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474110 n.453_454insCGGTG non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631_649delCCTTTTCCTCTCCGGAGGAinsTCGACTTTGTC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474415 n.760_765delACACGC non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474426 n.769T>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474428 n.771C>G non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1474429 n.772G>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474430 n.773C>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474711 n.1054_1063delGGTGTAAAGCinsCAAGTCCAAGAGT non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475382 n.1725A>G non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475395 n.1738T>C non_coding_transcript_exon_variant 0.87 capreomycin
linezolid Uncertain significance
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.97 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.9 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.88 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
inhA 1673682 c.-520G>C upstream_gene_variant 0.83 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673703 c.-499C>T upstream_gene_variant 0.83 ethionamide
isoniazid
fabG1 1673708 c.270_271delCC frameshift_variant 0.83 ethionamide
isoniazid
fabG1 1673714 c.275_276insT frameshift_variant 0.83 ethionamide
isoniazid
fabG1 1673717 c.278_279insA frameshift_variant 0.88 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673730 c.-472C>G upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673745 c.-457G>A upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.88 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.88 ethionamide
isoniazid
fabG1 1673760 p.Lys107Asn missense_variant 0.78 ethionamide
isoniazid
inhA 1673772 c.-430C>A upstream_gene_variant 0.78 ethionamide
isoniazid
inhA 1673778 c.-424C>G upstream_gene_variant 0.78 ethionamide
isoniazid
inhA 1673784 c.-418G>T upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1673787 c.-415G>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.91 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 0.92 ethionamide
isoniazid
inhA 1674702 c.501G>T synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674742 p.Lys181Ala missense_variant 0.93 ethionamide
isoniazid
inhA 1674745 p.Tyr182Ala missense_variant 0.81 ethionamide
isoniazid
inhA 1674753 c.552G>C synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674771 c.570C>T synonymous_variant 0.69 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674789 c.588G>T synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674795 c.594G>C synonymous_variant 0.64 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674804 c.603G>C synonymous_variant 0.6 ethionamide Not assoc w R - Interim
isoniazid
inhA 1674876 c.675C>T synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 0.82 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674930 c.729C>T synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674934 c.733C>T synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674949 p.Leu250Met missense_variant 0.79 ethionamide
isoniazid
inhA 1674954 c.753G>C synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674963 c.762G>A synonymous_variant 0.75 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674966 c.765T>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 0.82 ethionamide
isoniazid
rpsA 1833547 c.6G>A synonymous_variant 0.8 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.83 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.92 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.92 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 0.92 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.97 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.97 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.94 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.9 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.96 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1833709 c.168C>T synonymous_variant 0.94 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.91 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.91 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.97 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.95 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.95 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.91 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.91 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.95 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.95 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.93 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.93 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.96 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 0.95 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.91 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.95 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.95 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.94 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.83 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.91 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.91 pyrazinamide
rpsA 1834168 c.627C>T synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 0.91 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 0.81 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.9 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.94 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834402 c.861C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.96 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.93 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.94 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.94 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.9 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.86 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.88 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.89 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.96 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.96 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.96 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.95 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834829 c.1288_1290delGCGinsAC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
tsnR 1853361 c.-245T>C upstream_gene_variant 0.87 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.86 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 0.8 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.85 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.84 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.81 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.85 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.85 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.87 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.83 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.82 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 0.88 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.83 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.83 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.82 linezolid
katG 2155680 c.432G>A synonymous_variant 0.59 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.67 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.68 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.75 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.71 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.75 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.75 isoniazid
katG 2155747 p.Ala122Gly missense_variant 0.71 isoniazid
katG 2155749 c.363C>T synonymous_variant 0.71 isoniazid Not assoc w R - Interim
katG 2155752 c.360C>T synonymous_variant 0.71 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.64 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.64 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.75 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.85 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 0.75 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.72 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 0.74 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.77 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 0.69 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 0.69 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.7 isoniazid
kasA 2518636 c.522C>A synonymous_variant 0.8 isoniazid
kasA 2518708 c.594C>G synonymous_variant 0.7 isoniazid
kasA 2518726 c.612G>A synonymous_variant 0.81 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.82 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.87 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.92 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.91 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.95 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.9 isoniazid
kasA 2518787 c.673_675delCGGinsGT frameshift_variant&missense_variant 0.9 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.9 isoniazid
kasA 2518795 c.681C>T synonymous_variant 0.9 isoniazid
kasA 2518813 c.699C>T synonymous_variant 0.92 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.92 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.92 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.93 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.92 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.95 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.95 isoniazid
kasA 2518877 p.Lys255Leu missense_variant 0.88 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.94 isoniazid
kasA 2518903 c.789C>T synonymous_variant 0.88 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.93 isoniazid
kasA 2518907 c.793T>C synonymous_variant 0.94 isoniazid
kasA 2518910 p.Leu266Met missense_variant 1.0 isoniazid
kasA 2518936 c.822C>G synonymous_variant 0.64 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.7 isoniazid
kasA 2518942 c.828T>C synonymous_variant 0.7 isoniazid
Rv2477c 2782483 c.1560G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 0.85 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2752c 3065022 c.1170G>C synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065058 c.1134C>G synonymous_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065061 c.1131C>T synonymous_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065082 c.1110G>T synonymous_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 0.88 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 0.88 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 0.88 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065126 p.Ser356Ala missense_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1062A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>G synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067325 c.621A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067331 c.615C>T synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067334 c.612C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067340 c.606G>A synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067376 c.570G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067403 c.543C>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067415 c.531C>T synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067423 c.523C>T synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067424 c.522G>A synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067436 c.510C>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067442 c.504C>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067762 c.184C>A synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.62 para-aminosalicylic_acid
thyX 3067771 p.Gly59Ser missense_variant 0.62 para-aminosalicylic_acid
thyX 3067772 c.174C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067788 p.Lys53Arg missense_variant 0.62 para-aminosalicylic_acid
thyX 3067808 c.138C>T synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 0.71 para-aminosalicylic_acid
thyX 3067825 c.121C>A synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067829 c.117C>A synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067839 p.Val36Thr missense_variant 0.62 para-aminosalicylic_acid
thyX 3067841 c.105G>C synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067847 c.99C>T synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067862 c.84C>T synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073905 c.567C>T synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073926 c.546G>C synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073971 c.501C>T synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.62 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 0.62 para-aminosalicylic_acid
lpqB 3624023 c.888G>C synonymous_variant 0.73 bedaquiline
rifampicin
lpqB 3624032 c.879T>C synonymous_variant 0.83 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624037 c.874A>C synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3624041 p.Glu290Asp missense_variant 0.85 bedaquiline
rifampicin
lpqB 3624046 c.865C>T synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624060 p.Ala284Val missense_variant 0.89 bedaquiline
rifampicin
lpqB 3624074 c.837G>C synonymous_variant 0.89 bedaquiline
rifampicin
lpqB 3624080 p.Arg277Ser missense_variant 0.89 bedaquiline
rifampicin
lpqB 3624086 p.Asp275Gly missense_variant 0.89 bedaquiline
rifampicin
lpqB 3624094 c.817A>C synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624095 c.814_816delGCCinsTG frameshift_variant&missense_variant 0.85 bedaquiline
rifampicin Uncertain significance
lpqB 3624100 c.811T>C synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624101 c.810C>G synonymous_variant 0.85 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.79 bedaquiline
rifampicin
lpqB 3624133 c.778A>C synonymous_variant 0.77 bedaquiline
rifampicin
lpqB 3624134 c.777C>T synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624143 c.768T>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3624605 p.Glu102Asp missense_variant 0.6 bedaquiline
rifampicin Uncertain significance
lpqB 3624614 c.297A>C synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624617 c.294C>T synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624636 p.His92Arg missense_variant 0.89 bedaquiline
rifampicin Uncertain significance
lpqB 3624643 p.Ile90Leu missense_variant 0.8 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624650 c.261G>A synonymous_variant 0.8 bedaquiline
rifampicin
lpqB 3624656 c.255C>T synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3624673 p.Ala80Ser missense_variant 0.88 bedaquiline
rifampicin
lpqB 3624675 p.Asn79Ser missense_variant 0.88 bedaquiline
rifampicin
lpqB 3624680 c.231T>G synonymous_variant 0.92 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3624704 c.207G>C synonymous_variant 0.88 bedaquiline
rifampicin
lpqB 3624725 c.186G>T synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624734 c.177A>G synonymous_variant 0.76 bedaquiline
rifampicin
mtrB 3625032 c.1582C>T synonymous_variant 0.58 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625045 c.-135C>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 0.77 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>G upstream_gene_variant 0.77 bedaquiline
rifampicin
lpqB 3625072 c.-162G>C upstream_gene_variant 0.69 bedaquiline
rifampicin
lpqB 3625075 c.-165G>C upstream_gene_variant 0.69 bedaquiline
rifampicin
lpqB 3625078 c.-168G>T upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3625090 c.1524C>T synonymous_variant 0.82 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625095 p.Glu507Lys missense_variant 0.91 bedaquiline
rifampicin
mtrB 3625111 c.1503G>A synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625117 c.-207T>G upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625122 c.-212C>A upstream_gene_variant 0.67 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625135 c.-225A>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.87 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625186 c.-276T>G upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625195 c.-285A>G upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 0.62 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625243 c.-333T>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3625252 c.1362G>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625258 c.-348G>T upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3625264 c.1350C>T synonymous_variant 0.82 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625267 c.1347T>C synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625279 c.-369C>G upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625297 c.-387C>G upstream_gene_variant 0.78 bedaquiline
rifampicin
lpqB 3625312 c.-402G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 0.73 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625325 p.His430Arg missense_variant 0.76 bedaquiline
rifampicin
lpqB 3625336 c.-426C>T upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625381 c.-471T>C upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625615 c.-705G>T upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625623 p.Thr331Ala missense_variant 0.8 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 0.8 bedaquiline
rifampicin
lpqB 3625639 c.-729C>T upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3625645 c.969C>T synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625648 c.964_966delTATinsCC frameshift_variant&missense_variant 0.8 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625656 c.958T>C synonymous_variant 0.82 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625657 c.-747C>T upstream_gene_variant 0.73 bedaquiline
rifampicin
lpqB 3625663 c.-753G>A upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3625711 c.903C>T synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3625753 p.Ala287Gln missense_variant 0.84 bedaquiline
rifampicin
lpqB 3625762 c.-852A>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 0.85 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625804 c.808_810delAGGinsCC frameshift_variant&missense_variant 0.9 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625822 c.-912C>T upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625828 c.-918G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625837 c.777C>G synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 0.9 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626804 c.546A>G synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>T upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrA 3626864 c.484_486delTTGinsCC frameshift_variant&missense_variant 0.61 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.6 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3626894 c.-281C>T upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.59 bedaquiline
rifampicin
mtrA 3626906 c.442_444delAACinsCG frameshift_variant&missense_variant 0.55 bedaquiline
rifampicin
mtrA 3626909 c.441C>T synonymous_variant 0.55 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3626912 c.438T>C synonymous_variant 0.59 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626930 c.-317A>G upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.61 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.57 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.52 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrA 3626962 p.Met130Leu missense_variant 0.6 bedaquiline
rifampicin
mtrA 3626969 c.381C>T synonymous_variant 0.67 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.66 bedaquiline
rifampicin Uncertain significance
mtrB 3626999 c.-386G>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3627002 c.-389G>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627005 c.-392G>A upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.68 bedaquiline
rifampicin
mtrB 3627044 c.-431C>T upstream_gene_variant 0.65 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627062 c.-449G>A upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
rpoA 3877534 p.Val325Ala missense_variant 0.93 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 0.95 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 0.95 rifampicin
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 0.95 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.96 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.88 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.88 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.88 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant