TB-Profiler result

Run: ERR736817
Summary

Run ID: ERR736817

Sample name:

Date: 2024-03-26T16:21:12.248756

Number of reads: 1091296

Percentage reads mapped: 18.42

Median coverage: 17.0

Strain: lineage4.3.4

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.3 Euro-American (LAM) None 1.0
lineage4 Euro-American None 1.0
lineage4.3.4 Euro-American (LAM) RD174 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ser140Asn Uncertain significance Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide ethA c.1150_1152delGTTinsAC Assoc w R
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.1567_1569delCCTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.59 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.74 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304497 c.1567_1569delCCTinsAC frameshift_variant&missense_variant 0.41 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155693 p.Ser140Asn missense_variant 0.44 isoniazid Uncertain significance Mutation from literature
ethA 4326322 c.1150_1152delGTTinsAC frameshift_variant&missense_variant 0.64 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 690 c.690G>C synonymous_variant 0.38 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.5 isoniazid
dnaA 699 c.699G>C synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.79 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.79 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.82 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.78 isoniazid
dnaA 762 c.762C>G synonymous_variant 0.74 isoniazid Not assoc w R - Interim
dnaA 765 c.766_767insCG frameshift_variant 0.74 isoniazid Uncertain significance
dnaA 769 c.770_771delCA frameshift_variant 0.74 isoniazid Uncertain significance
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.68 isoniazid Uncertain significance
dnaA 802 c.802C>T synonymous_variant 0.65 isoniazid
dnaA 805 c.805T>C synonymous_variant 0.63 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.66 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.62 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.59 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.57 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.57 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.57 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.56 isoniazid
dnaA 864 c.864C>T synonymous_variant 0.67 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.66 isoniazid
dnaA 888 c.888C>G synonymous_variant 0.7 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.73 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.69 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>G synonymous_variant 0.69 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.69 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.7 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.72 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.72 isoniazid
dnaA 955 c.955_957delAGAinsCC frameshift_variant&missense_variant 0.73 isoniazid Uncertain significance
dnaA 966 c.966T>C synonymous_variant 0.72 isoniazid
dnaA 975 c.975G>A synonymous_variant 0.69 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 0.65 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.49 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.51 isoniazid
dnaA 999 c.999C>G synonymous_variant 0.49 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 0.51 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.6 isoniazid Not assoc w R - Interim
dnaA 1014 c.1014C>G synonymous_variant 0.6 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.57 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.56 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 0.6 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.58 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 0.6 isoniazid
dnaA 1047 p.Glu349Asp missense_variant 0.62 isoniazid
dnaA 1055 p.Ala352Asp missense_variant 0.6 isoniazid
dnaA 1059 c.1059C>T synonymous_variant 0.58 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.67 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.65 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.65 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.55 isoniazid
dnaA 1107 c.1107C>T synonymous_variant 0.5 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.5 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 0.41 isoniazid
dnaA 1134 c.1134G>C synonymous_variant 0.38 isoniazid
dnaA 1137 c.1137C>A synonymous_variant 0.33 isoniazid
dnaA 1140 c.1140C>G synonymous_variant 0.3 isoniazid
gyrB 6100 c.861G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrB 6140 c.901_903delGTGinsTA frameshift_variant&stop_gained 0.37 levofloxacin Uncertain significance
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 6202 c.963C>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6203 p.Ser322Ala missense_variant 0.45 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.46 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.29 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.26 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.39 levofloxacin
moxifloxacin
gyrA 6532 c.-770C>T upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312_1314delTTGinsCC frameshift_variant&missense_variant 0.39 levofloxacin Uncertain significance
moxifloxacin
gyrA 6556 c.-746C>A upstream_gene_variant 0.48 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6580 c.1341C>T synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>A upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6778 c.-524C>T upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.51 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.56 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.43 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7114 c.-188C>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 7174 c.-128C>T upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7210 p.Asp657Glu missense_variant 0.64 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 7216 c.-86G>T upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7237 c.-65C>T upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 7243 c.-59G>A upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 7246 c.2007T>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7252 c.-50G>T upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7258 c.-44G>T upstream_gene_variant 0.31 levofloxacin
moxifloxacin
gyrA 7343 c.42G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7358 c.57C>T synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7415 c.114C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7448 c.147G>A synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7454 c.153G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7484 c.183T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7673 c.372G>A synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7710 c.409_411delTTGinsCT frameshift_variant&synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7766 c.465C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7775 c.474C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8147 c.846C>T synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8190 p.Ala297Asn missense_variant 0.35 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.34 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.34 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8267 c.966G>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 0.67 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8357 c.1056G>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8367 c.1066C>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.44 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8400 p.Asp367Asn missense_variant 0.4 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>T synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8588 p.Glu429Asp missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8597 c.1296C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8720 c.1419G>A synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>G synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 0.46 levofloxacin
moxifloxacin
gyrA 8738 c.1437G>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8741 c.1440C>T synonymous_variant 0.3 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8795 c.1494C>T synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8796 c.1495_1497delATCinsGG frameshift_variant&missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 8813 c.1512C>T synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8816 c.1515C>T synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 8817 p.Ser506Ala missense_variant 0.41 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 8951 c.1650G>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.8 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9044 c.1743C>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>T synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9104 c.1803C>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9161 c.1860C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9188 c.1887C>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9207 p.Lys636Arg missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 9213 p.Thr638Val missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9257 c.1956C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>T synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 9300 p.Ala667Ser missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9320 c.2019G>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9332 p.Asn677Lys missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9368 c.2067G>A synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9369 c.2068C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9386 c.2085T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9389 c.2088C>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9398 c.2097T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Ala missense_variant 0.6 levofloxacin
moxifloxacin
fgd1 491043 c.261T>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491055 c.273C>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 0.57 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491073 c.291C>T synonymous_variant 0.57 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491082 c.300T>G synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.58 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491491 p.Pro237Thr missense_variant 0.61 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491521 c.739C>A synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 491532 c.750G>A synonymous_variant 0.67 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491542 c.760T>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_782delAGinsTC synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491603 p.Ala274Glu missense_variant 0.69 clofazimine
pretomanid
delamanid
fgd1 491605 c.823C>T synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.7 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491652 c.870C>G synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.41 clofazimine
pretomanid
delamanid
mshA 575665 c.318G>T synonymous_variant 0.54 ethionamide
isoniazid Not assoc w R - Interim
mshA 575686 c.339G>C synonymous_variant 0.64 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 0.64 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.64 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>G synonymous_variant 0.63 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 0.63 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575732 c.385_387delCTTinsTG frameshift_variant&missense_variant 0.65 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575737 c.390T>C synonymous_variant 0.66 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.64 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 0.61 ethionamide
isoniazid
mshA 575756 c.409C>T synonymous_variant 0.59 ethionamide
isoniazid
mshA 575761 c.414C>G synonymous_variant 0.56 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 0.52 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 0.61 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 0.66 ethionamide
isoniazid Not assoc w R - Interim
mshA 575818 c.471G>C synonymous_variant 0.7 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.69 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.75 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.84 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.83 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 0.78 ethionamide
isoniazid
mshA 575908 c.561A>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 575911 c.564G>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575917 p.Asp190Glu missense_variant 0.82 ethionamide
isoniazid
mshA 575924 p.Gly193Ser missense_variant 0.79 ethionamide
isoniazid
mshA 575932 c.585G>A synonymous_variant 0.74 ethionamide
isoniazid
mshA 575935 c.588G>T synonymous_variant 0.75 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.71 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 0.69 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.67 ethionamide
isoniazid Not assoc w R - Interim
mshA 575977 c.630G>C synonymous_variant 0.55 ethionamide
isoniazid
mshA 575980 c.633T>C synonymous_variant 0.5 ethionamide
isoniazid
ccsA 620319 c.429C>T synonymous_variant 0.33 capreomycin
amikacin
kanamycin
ccsA 620325 c.435G>T synonymous_variant 0.39 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>C synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620352 c.462C>T synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620362 c.472_474delGCCinsAG frameshift_variant&missense_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>A synonymous_variant 0.65 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.62 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620436 c.546T>C synonymous_variant 0.59 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620442 c.552G>C synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620466 c.576C>G synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>C synonymous_variant 0.53 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620616 c.726C>T synonymous_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 0.55 capreomycin
amikacin
kanamycin
ccsA 620622 c.732G>C synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620685 c.795G>A synonymous_variant 0.65 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620694 c.804C>G synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620709 c.819G>C synonymous_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620724 c.834C>T synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>T synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>C synonymous_variant 0.38 capreomycin
amikacin
kanamycin
nusG 734384 p.Ser44Thr missense_variant 0.32 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.54 rifampicin
nusG 734418 c.165C>T synonymous_variant 0.59 rifampicin Not assoc w R - Interim
nusG 734421 c.168A>C synonymous_variant 0.59 rifampicin
nusG 734424 c.171G>T synonymous_variant 0.62 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.76 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.81 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.81 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.84 rifampicin
nusG 734463 c.210G>A synonymous_variant 0.82 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.85 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.88 rifampicin
nusG 734508 c.255C>G synonymous_variant 0.85 rifampicin
nusG 734511 c.258C>T synonymous_variant 0.86 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.72 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
nusG 734586 c.333G>C synonymous_variant 0.4 rifampicin
nusG 734807 p.Tyr185Phe missense_variant 0.68 rifampicin
nusG 734820 c.567A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 0.74 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.75 rifampicin
nusG 734850 c.597C>G synonymous_variant 0.73 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.73 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.75 rifampicin
nusG 734863 p.Thr204Ser missense_variant 0.74 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.64 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.52 rifampicin
nusG 734934 c.681G>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
nusG 734940 c.687G>A synonymous_variant 0.21 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.72 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.71 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.71 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.67 rifampicin Uncertain significance
rpoB 760139 c.333A>C synonymous_variant 0.68 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.68 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.85 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.85 rifampicin
rpoB 760323 c.517C>T synonymous_variant 0.86 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.86 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.86 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.86 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.86 rifampicin
rpoB 760343 c.537G>C synonymous_variant 0.86 rifampicin
rpoB 760357 p.Thr184Ser missense_variant 0.82 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.8 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.79 rifampicin Uncertain significance
rpoB 760407 p.Ser201Gly missense_variant 0.8 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.63 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>T synonymous_variant 0.67 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.68 rifampicin
rpoB 760514 c.708C>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.69 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.62 rifampicin
rpoB 760541 c.735G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.82 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.75 rifampicin
rpoB 760601 c.795C>T synonymous_variant 0.75 rifampicin
rpoB 760611 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.79 rifampicin
rpoB 760629 c.823C>T synonymous_variant 0.83 rifampicin
rpoB 760640 c.834C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.8 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 0.38 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 0.67 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.64 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.72 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.73 rifampicin
rpoB 761126 c.1320G>C synonymous_variant 0.75 rifampicin
rpoB 761132 c.1326G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761234 c.1428G>C synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>T synonymous_variant 0.39 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.41 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 0.48 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.41 rifampicin
rpoB 761346 p.Val514Lys missense_variant 0.41 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.39 rifampicin
rpoB 761357 c.1551G>C synonymous_variant 0.38 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.39 rifampicin
rpoB 761369 p.Glu521Asp missense_variant 0.5 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.53 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.51 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.52 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.54 rifampicin
rpoB 761437 p.Ala544Glu missense_variant 0.52 rifampicin
rpoB 761439 p.Asp545Asn missense_variant 0.52 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.52 rifampicin
rpoB 761457 p.Pro551Asp missense_variant 0.45 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.62 rifampicin
rpoB 761564 c.1758G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.78 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.74 rifampicin
rpoB 761661 c.1855C>T synonymous_variant 0.74 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.75 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.71 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.66 rifampicin
rpoB 761718 p.Ala638Ser missense_variant 0.49 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.41 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.42 rifampicin
rpoB 761736 p.Ile644Val missense_variant 0.42 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 0.63 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.64 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.58 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.65 rifampicin
rpoB 761786 c.1980C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761791 p.Arg662His missense_variant 0.62 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.64 rifampicin
rpoB 761816 c.2010C>A synonymous_variant 0.61 rifampicin
rpoB 761819 c.2013G>T synonymous_variant 0.62 rifampicin
rpoB 761822 c.2016C>G synonymous_variant 0.62 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.62 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 0.38 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.3 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 0.27 rifampicin
rpoB 761882 c.2076C>G synonymous_variant 0.42 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.52 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.82 rifampicin
rpoB 762014 c.2208C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762098 c.2292C>T synonymous_variant 0.79 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.76 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.79 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.79 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.79 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.82 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.86 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762251 c.2445G>C synonymous_variant 0.73 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 0.71 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 0.7 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 0.6 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 0.57 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.5 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 762359 c.2553C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 0.55 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.64 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.64 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.67 rifampicin
rpoC 762390 c.-980C>T upstream_gene_variant 0.59 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.59 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.59 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.59 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 0.57 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 762482 c.-888C>T upstream_gene_variant 0.73 rifampicin
rpoB 762488 c.2682G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 762503 c.-867G>C upstream_gene_variant 0.79 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.77 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.78 rifampicin Uncertain significance
rpoC 762533 c.-837T>C upstream_gene_variant 0.7 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.71 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.71 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.68 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.64 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.61 rifampicin
rpoC 762575 c.-795C>T upstream_gene_variant 0.54 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.45 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.45 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 0.58 rifampicin Uncertain significance
rpoB 762782 c.2976T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.59 rifampicin Uncertain significance
rpoB 762786 p.Val994Thr missense_variant 0.59 rifampicin
rpoC 762791 c.-579G>C upstream_gene_variant 0.61 rifampicin
rpoB 762799 p.Ala998Glu missense_variant 0.61 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762818 c.3012C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 762827 c.-543G>T upstream_gene_variant 0.75 rifampicin
rpoB 762833 c.3027C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 762836 c.3030C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 762851 c.-519C>T upstream_gene_variant 0.74 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 762863 c.-507T>G upstream_gene_variant 0.74 rifampicin
rpoB 762879 p.Met1025Leu missense_variant 0.78 rifampicin Uncertain significance
rpoC 762917 c.-453C>T upstream_gene_variant 0.83 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762947 c.3141C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.74 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.72 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.72 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 763172 c.3366G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.54 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.52 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 0.52 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763217 c.-153G>C upstream_gene_variant 0.5 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.5 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.5 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.49 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 0.49 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 0.41 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.39 rifampicin
rpoC 763375 c.6C>A synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.7 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.7 rifampicin
rpoC 763420 c.51G>C synonymous_variant 0.72 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.72 rifampicin Uncertain significance
rpoC 763429 c.60C>T synonymous_variant 0.74 rifampicin
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763435 c.66A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.81 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 763639 c.270G>A synonymous_variant 0.76 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>T synonymous_variant 0.8 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763720 c.351G>C synonymous_variant 0.8 rifampicin
rpoC 763723 c.354G>C synonymous_variant 0.78 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.79 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.77 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.78 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.76 rifampicin
rpoC 763774 c.405G>C synonymous_variant 0.73 rifampicin
rpoC 763781 c.412_414delTCGinsGC frameshift_variant&missense_variant 0.72 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.69 rifampicin
rpoC 763801 c.432C>T synonymous_variant 0.65 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.61 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.62 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.57 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.54 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 763925 p.Ala186Lys missense_variant 0.53 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.54 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 0.51 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.5 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.51 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 763972 c.603C>T synonymous_variant 0.67 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.68 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.66 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.66 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.6 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.61 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.68 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.7 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.68 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.67 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.6 rifampicin
rpoC 764095 c.726C>G synonymous_variant 0.69 rifampicin
rpoC 764101 c.732C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.69 rifampicin
rpoC 764126 p.Thr253Ala missense_variant 0.66 rifampicin
rpoC 764134 c.765C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764143 c.774G>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764147 c.778_780delTCGinsGC frameshift_variant&missense_variant 0.36 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.4 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.6 rifampicin
rpoC 764179 c.810C>T synonymous_variant 0.74 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 0.75 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Glu missense_variant 0.78 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.77 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.77 rifampicin
rpoC 764239 c.870T>C synonymous_variant 0.84 rifampicin
rpoC 764245 c.876C>G synonymous_variant 0.83 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.84 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.83 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.82 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764285 p.Gly306Ser missense_variant 0.82 rifampicin
rpoC 764317 c.948C>G synonymous_variant 0.82 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.81 rifampicin
rpoC 764329 c.960C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.61 rifampicin
rpoC 764386 c.1017C>T synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.58 rifampicin
rpoC 764392 c.1023C>T synonymous_variant 0.56 rifampicin
rpoC 764395 c.1026C>T synonymous_variant 0.59 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.68 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.69 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.68 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.69 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.71 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.82 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.84 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.83 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 0.93 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.9 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 0.9 rifampicin
rpoC 764611 c.1242G>C synonymous_variant 0.87 rifampicin
rpoC 764632 c.1263T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764755 c.1386C>T synonymous_variant 0.89 rifampicin
rpoC 764791 c.1422C>A synonymous_variant 0.85 rifampicin
rpoC 764797 c.1428G>C synonymous_variant 0.85 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.83 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.81 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.7 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.68 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.6 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.63 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.66 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.66 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 764956 c.1587T>C synonymous_variant 0.58 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.38 rifampicin Not assoc w R
rpoC 764998 c.1629G>T synonymous_variant 0.58 rifampicin
rpoC 765004 c.1635G>T synonymous_variant 0.42 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.43 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.43 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.49 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 0.44 rifampicin
rpoC 765085 c.1716T>G synonymous_variant 0.42 rifampicin
rpoC 765103 c.1734G>T synonymous_variant 0.52 rifampicin
rpoC 765121 c.1752G>C synonymous_variant 0.45 rifampicin
rpoC 765409 c.2040T>A synonymous_variant 0.32 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.59 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.63 rifampicin
rpoC 765452 p.Ala695Arg missense_variant 0.62 rifampicin
rpoC 765458 p.Ile697Val missense_variant 0.68 rifampicin Uncertain significance
rpoC 765466 c.2097C>T synonymous_variant 0.68 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.76 rifampicin Uncertain significance
rpoC 765499 c.2130C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.88 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.88 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.88 rifampicin
rpoC 765596 p.Lys743Gln missense_variant 0.74 rifampicin
rpoC 765607 c.2238C>G synonymous_variant 0.73 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.62 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.58 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.58 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.59 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.63 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.62 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765812 c.2443_2445delCGAinsAG frameshift_variant&synonymous_variant 0.62 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.66 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.71 rifampicin Uncertain significance
rpoC 765883 c.2514C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765886 c.2517C>G synonymous_variant 0.75 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.65 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 0.65 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.65 rifampicin
rpoC 765967 c.2598C>G synonymous_variant 0.65 rifampicin
rpoC 765970 c.2601C>A synonymous_variant 0.66 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 0.41 rifampicin
rpoC 766357 c.2988C>T synonymous_variant 0.58 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 0.63 rifampicin
rpoC 766366 c.2997C>G synonymous_variant 0.64 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.65 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.74 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.75 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.75 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 0.78 rifampicin
rpoC 766423 c.3054T>C synonymous_variant 0.85 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 0.83 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 0.77 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 0.81 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 0.81 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 0.81 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.81 rifampicin
rpoC 766531 c.3162G>C synonymous_variant 0.81 rifampicin
rpoC 766537 c.3168G>A synonymous_variant 0.83 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.84 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.8 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.65 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 0.59 rifampicin
rpoC 766588 c.3219G>A synonymous_variant 0.61 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766667 p.Ser1100Ala missense_variant 0.5 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 0.59 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.63 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 766712 c.3343_3345delTCGinsGT frameshift_variant&missense_variant 0.63 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 0.73 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.76 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.79 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.81 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.83 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.81 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 0.8 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.8 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.81 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.67 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766888 c.3519G>A synonymous_variant 0.56 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.54 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.54 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.54 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 0.43 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 0.53 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766951 c.3582G>C synonymous_variant 0.73 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>T synonymous_variant 0.8 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767056 c.3687C>A synonymous_variant 0.83 rifampicin
rpoC 767059 c.3690T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 0.86 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.84 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 767200 c.3831G>A synonymous_variant 0.81 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.46 rifampicin
rpoC 767275 c.3906T>G synonymous_variant 0.45 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.47 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 775865 c.2616T>C synonymous_variant 0.42 clofazimine
bedaquiline
mmpL5 775875 p.Gly869Ala missense_variant 0.25 clofazimine
bedaquiline
mmpL5 775885 p.Ile866Leu missense_variant 0.31 clofazimine
bedaquiline
mmpL5 775886 c.2595A>G synonymous_variant 0.42 clofazimine
bedaquiline
mmpL5 775889 c.2592C>G synonymous_variant 0.41 clofazimine
bedaquiline
mmpL5 775893 p.His863Pro missense_variant 0.56 clofazimine
bedaquiline
mmpL5 775895 c.2584_2586delATCinsCG frameshift_variant&missense_variant 0.25 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775907 c.2572_2574delCTCinsTG frameshift_variant&synonymous_variant 0.28 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775913 c.2566_2568delGCCinsTG frameshift_variant&missense_variant 0.24 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>C synonymous_variant 0.39 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.23 clofazimine
bedaquiline
mmpL5 775922 c.2559G>C synonymous_variant 0.31 clofazimine
bedaquiline
mmpL5 775939 p.Ala848Ser missense_variant 0.24 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.51 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.28 clofazimine
bedaquiline
mmpL5 776678 c.1803G>A synonymous_variant 0.39 clofazimine
bedaquiline
mmpL5 776681 c.1798_1800delCTGinsTC frameshift_variant&synonymous_variant 0.38 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776686 p.Ser599Ala missense_variant 0.38 clofazimine
bedaquiline
mmpL5 776695 p.Val596Ile missense_variant 0.38 clofazimine
bedaquiline
mmpL5 776704 p.Asp593Asn missense_variant 0.48 clofazimine
bedaquiline
mmpL5 776706 p.Tyr592Phe missense_variant 0.5 clofazimine
bedaquiline
mmpL5 777133 p.Val450Ile missense_variant 0.61 clofazimine
bedaquiline
mmpL5 777142 p.Val447Leu missense_variant 0.72 clofazimine
bedaquiline
mmpL5 777164 c.1317C>A synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777170 c.1311T>C synonymous_variant 0.7 clofazimine
bedaquiline
mmpL5 777173 c.1308C>G synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777176 p.Glu435Asp missense_variant 0.67 clofazimine
bedaquiline
mmpL5 777179 c.1302G>C synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 777188 c.1293T>C synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 777191 c.1290C>G synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 777194 c.1285_1287delGAAinsCG frameshift_variant&missense_variant 0.64 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777206 c.1275A>G synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 777227 c.1254C>G synonymous_variant 0.64 clofazimine
bedaquiline
mmpL5 777245 c.1236G>C synonymous_variant 0.36 clofazimine
bedaquiline
mmpS5 779609 c.-704C>T upstream_gene_variant 0.9 clofazimine
bedaquiline
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781628 c.69T>C synonymous_variant 0.5 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.51 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.47 streptomycin
rpsL 781652 c.93T>C synonymous_variant 0.47 streptomycin
rpsL 781655 c.96T>A synonymous_variant 0.48 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.5 streptomycin
rpsL 781676 c.117C>G synonymous_variant 0.54 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.57 streptomycin
rpsL 781703 c.144G>A synonymous_variant 0.61 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.52 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.47 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.4 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.41 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.39 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.39 streptomycin
rpsL 781737 p.Gln60Ala missense_variant 0.39 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.59 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.62 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.63 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.65 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.83 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.86 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.86 streptomycin Not assoc w R - Interim
rpsL 781862 c.303G>C synonymous_variant 0.86 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.86 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.86 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.84 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.84 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.86 streptomycin
rpsL 781898 c.339A>G synonymous_variant 0.85 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.84 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.84 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.84 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.41 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.37 linezolid
rplC 800537 c.-272C>G upstream_gene_variant 0.32 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.31 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.4 linezolid
rplC 800564 c.-245C>G upstream_gene_variant 0.45 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.51 linezolid
rplC 800597 c.-212A>T upstream_gene_variant 0.5 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.5 linezolid
rplC 800603 c.-206G>T upstream_gene_variant 0.54 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.64 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.65 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.74 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.77 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.79 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.81 linezolid
rplC 800693 c.-116A>T upstream_gene_variant 0.87 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.87 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.85 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.86 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.85 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 0.76 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.75 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.71 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.68 linezolid
rplC 800829 c.21C>G synonymous_variant 0.67 linezolid
rplC 800832 c.24T>C synonymous_variant 0.68 linezolid
rplC 800844 c.36T>C synonymous_variant 0.78 linezolid
rplC 800856 c.48A>G synonymous_variant 0.83 linezolid
rplC 800865 c.57A>G synonymous_variant 0.82 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.8 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.78 linezolid
rplC 800877 c.69A>C synonymous_variant 0.79 linezolid
rplC 800880 c.72A>G synonymous_variant 0.82 linezolid
rplC 800889 c.81C>G synonymous_variant 0.84 linezolid
rplC 800892 c.84G>C synonymous_variant 0.85 linezolid
rplC 800916 c.108A>G synonymous_variant 0.86 linezolid
rplC 800919 c.111C>G synonymous_variant 0.85 linezolid
rplC 800934 c.126C>G synonymous_variant 0.8 linezolid
rplC 800937 c.129A>G synonymous_variant 0.77 linezolid
rplC 800946 c.138T>G synonymous_variant 0.71 linezolid
rplC 800949 c.141T>C synonymous_variant 0.69 linezolid
rplC 800955 c.147C>T synonymous_variant 0.69 linezolid
rplC 800970 c.162T>C synonymous_variant 0.66 linezolid Not assoc w R - Interim
rplC 800985 c.177A>C synonymous_variant 0.56 linezolid
rplC 801132 c.324T>C synonymous_variant 0.6 linezolid
rplC 801137 p.Ser110Thr missense_variant 0.58 linezolid
rplC 801141 c.333C>T synonymous_variant 0.56 linezolid
rplC 801147 c.339T>C synonymous_variant 0.56 linezolid
rplC 801153 c.345G>C synonymous_variant 0.54 linezolid
rplC 801156 c.348T>C synonymous_variant 0.5 linezolid
rplC 801160 c.352_353delTCinsAG synonymous_variant 0.5 linezolid
rplC 801171 c.363A>G synonymous_variant 0.66 linezolid
rplC 801174 c.366T>C synonymous_variant 0.66 linezolid
rplC 801186 c.378C>G synonymous_variant 0.67 linezolid
rplC 801195 c.387G>C synonymous_variant 0.69 linezolid
rplC 801222 c.414T>C synonymous_variant 0.59 linezolid
rplC 801228 c.420T>C synonymous_variant 0.56 linezolid
rplC 801231 c.423C>G synonymous_variant 0.55 linezolid
rplC 801237 c.429G>T synonymous_variant 0.55 linezolid
rplC 801249 c.441T>C synonymous_variant 0.5 linezolid
rplC 801252 c.444G>C synonymous_variant 0.49 linezolid
fbiC 1303492 c.562T>C synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 0.69 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1303530 c.600G>A synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1303536 c.606G>T synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1303539 c.609G>A synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fbiC 1303607 p.Lys226Arg missense_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304079 p.Glu383Asp missense_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>T synonymous_variant 0.37 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.42 clofazimine
pretomanid
delamanid
fbiC 1304106 c.1176G>C synonymous_variant 0.39 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>T synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1304503 c.1573C>T synonymous_variant 0.44 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304508 p.Glu526Asp missense_variant 0.5 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>G synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304523 c.1593G>T synonymous_variant 0.51 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304619 c.1689G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304661 c.1731C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304667 c.1737G>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.62 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.45 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.44 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1304961 c.2031C>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304967 c.2037G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1305007 p.Ile693Val missense_variant 0.65 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fbiC 1305030 c.2100G>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>G synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.52 clofazimine
pretomanid
delamanid
sigE 1364679 c.267T>C synonymous_variant 0.35 pyrazinamide
sigE 1364697 c.285G>C synonymous_variant 0.46 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.46 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.46 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 0.44 pyrazinamide
sigE 1364718 c.306C>G synonymous_variant 0.44 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.44 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.46 pyrazinamide
sigE 1364727 c.315C>T synonymous_variant 0.46 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.56 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.61 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.56 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.6 pyrazinamide
sigE 1364778 c.366G>A synonymous_variant 0.48 pyrazinamide
sigE 1364782 c.370_372delGTCinsCG frameshift_variant&missense_variant 0.46 pyrazinamide Uncertain significance
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 0.42 pyrazinamide Uncertain significance
sigE 1364839 c.427T>C synonymous_variant 0.42 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.35 pyrazinamide
sigE 1364856 c.444C>T synonymous_variant 0.35 pyrazinamide
sigE 1364862 c.450C>A synonymous_variant 0.38 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.38 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.38 pyrazinamide
sigE 1364877 c.465G>C synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
sigE 1364886 c.474G>A synonymous_variant 0.46 pyrazinamide
sigE 1364887 c.475T>C synonymous_variant 0.46 pyrazinamide
atpE 1461042 c.-2delA upstream_gene_variant 0.4 bedaquiline
atpE 1461050 c.6C>T synonymous_variant 0.55 bedaquiline
atpE 1461071 c.27C>G synonymous_variant 0.68 bedaquiline
atpE 1461101 c.57T>C synonymous_variant 0.77 bedaquiline
atpE 1461107 c.63C>A synonymous_variant 0.74 bedaquiline
atpE 1461131 c.87T>C synonymous_variant 0.74 bedaquiline
atpE 1461132 p.Val30Ile missense_variant 0.76 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.72 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.62 bedaquiline
atpE 1461153 p.Ser37Ala missense_variant 0.59 bedaquiline Uncertain significance
atpE 1461158 c.114T>C synonymous_variant 0.56 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.56 bedaquiline Uncertain significance
atpE 1461164 c.120C>T synonymous_variant 0.6 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.64 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.6 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.59 bedaquiline
atpE 1461188 c.144G>A synonymous_variant 0.6 bedaquiline
atpE 1461191 c.147G>C synonymous_variant 0.57 bedaquiline
atpE 1461197 c.153A>T synonymous_variant 0.59 bedaquiline
atpE 1461212 c.168C>G synonymous_variant 0.46 bedaquiline
atpE 1461215 c.171C>G synonymous_variant 0.47 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 0.49 bedaquiline
atpE 1461224 c.180T>C synonymous_variant 0.49 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 0.47 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 0.61 bedaquiline
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.89 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.89 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.9 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.9 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.81 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.76 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.21 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.18 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.54 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.52 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.51 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.53 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.63 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.62 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.94 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472844 n.1000dupG non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1005delT non_coding_transcript_exon_variant 0.82 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472856 n.1012delA non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1018dupT non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.85 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.83 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.82 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.91 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473658 n.1T>G non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.69 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.71 capreomycin
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.81 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.57 capreomycin Uncertain significance
linezolid
rrl 1474287 n.630delTinsCTCG non_coding_transcript_exon_variant 0.4 capreomycin
linezolid
rrl 1474289 n.632C>A non_coding_transcript_exon_variant 0.44 capreomycin
linezolid
rrl 1474293 n.637_647delCCTCTCCGGAG non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1474710 n.1053delTinsGCAA non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475403 n.1746T>G non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.33 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.21 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.24 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.26 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.25 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.34 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.34 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.23 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3033_3034delCT non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
inhA 1673646 c.-556T>C upstream_gene_variant 0.42 ethionamide
isoniazid
inhA 1673652 c.-550C>A upstream_gene_variant 0.44 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.44 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.45 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.5 ethionamide
isoniazid
inhA 1673673 c.-529C>T upstream_gene_variant 0.54 ethionamide
isoniazid
inhA 1673697 c.-505G>C upstream_gene_variant 0.7 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.7 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.7 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.75 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.73 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.73 ethionamide
isoniazid
inhA 1673757 c.-445G>A upstream_gene_variant 0.74 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.74 ethionamide
isoniazid
inhA 1673778 c.-424C>G upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1673793 c.-409G>A upstream_gene_variant 0.65 ethionamide
isoniazid
inhA 1673796 c.-406G>C upstream_gene_variant 0.62 ethionamide
isoniazid
inhA 1673799 c.-403T>C upstream_gene_variant 0.6 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.61 ethionamide
isoniazid
inhA 1673808 c.-394A>C upstream_gene_variant 0.68 ethionamide
isoniazid
fabG1 1673816 p.Ser126Thr missense_variant 0.7 ethionamide
isoniazid
inhA 1673862 c.-340C>G upstream_gene_variant 0.5 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 0.59 ethionamide
isoniazid
inhA 1673901 c.-301A>C upstream_gene_variant 0.62 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.6 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.58 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.58 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.6 ethionamide
isoniazid
fabG1 1673941 c.502_504delGCCinsTG frameshift_variant&missense_variant 0.54 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.49 ethionamide
isoniazid
fabG1 1673960 p.Ala174Val missense_variant 0.32 ethionamide
isoniazid
inhA 1674331 p.Leu44Met missense_variant 0.3 ethionamide
isoniazid
inhA 1674334 p.Arg45Lys missense_variant 0.3 ethionamide
isoniazid
inhA 1674342 c.141T>C synonymous_variant 0.32 ethionamide
isoniazid
inhA 1674352 p.Thr51Ala missense_variant 0.35 ethionamide Uncertain significance
isoniazid
inhA 1674366 c.166_168delGCA conservative_inframe_deletion 0.33 ethionamide
isoniazid
inhA 1674372 c.171_174delGGCCinsTCCGGCG missense_variant&conservative_inframe_insertion 0.35 ethionamide
isoniazid
inhA 1674384 c.183C>G synonymous_variant 0.3 ethionamide
isoniazid
inhA 1674399 c.198A>G synonymous_variant 0.32 ethionamide
isoniazid
inhA 1674463 p.Leu88Ile missense_variant 0.52 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674474 c.273G>C synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.71 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.74 ethionamide
isoniazid
inhA 1674489 c.288G>C synonymous_variant 0.77 ethionamide
isoniazid
inhA 1674502 c.301_303delACCinsTG frameshift_variant&missense_variant 0.81 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 0.82 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674542 p.Ala114Glu missense_variant 0.81 ethionamide
isoniazid
inhA 1674552 c.351C>G synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.77 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674573 c.372G>A synonymous_variant 0.75 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.77 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.7 ethionamide
isoniazid
inhA 1674600 c.399G>C synonymous_variant 0.67 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.67 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 0.62 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674628 c.427_428delTCinsAG synonymous_variant 0.62 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 0.71 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 0.65 ethionamide
isoniazid
inhA 1674687 c.486G>C synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.52 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 0.46 ethionamide
isoniazid
inhA 1674718 c.517_519delAGGinsCC frameshift_variant&missense_variant 0.46 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674729 c.528G>T synonymous_variant 0.38 ethionamide
isoniazid
inhA 1674873 c.672G>A synonymous_variant 0.55 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 0.56 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674892 p.Asn231Asp missense_variant 0.52 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674904 p.Ala235Pro missense_variant 0.57 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674924 c.723G>C synonymous_variant 0.61 ethionamide
isoniazid
inhA 1674933 c.732G>C synonymous_variant 0.54 ethionamide
isoniazid
inhA 1674937 c.736C>T synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674942 c.741T>G synonymous_variant 0.53 ethionamide
isoniazid
inhA 1674954 c.753G>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674957 c.756G>C synonymous_variant 0.5 ethionamide
isoniazid
inhA 1674963 c.762G>C synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 0.56 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 0.56 ethionamide
isoniazid
inhA 1674970 p.Ile257Val missense_variant 0.56 ethionamide
isoniazid
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 0.67 pyrazinamide
rpsA 1833547 c.6G>A synonymous_variant 0.7 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.76 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 0.84 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.84 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.82 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.83 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 0.85 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.88 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.81 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.8 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.81 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.82 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.81 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.83 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 0.84 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
rpsA 1833709 c.168C>T synonymous_variant 0.86 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.87 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.88 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.89 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 0.89 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.91 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.91 pyrazinamide
rpsA 1833748 c.207C>T synonymous_variant 0.89 pyrazinamide
rpsA 1833778 c.237C>T synonymous_variant 0.94 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.92 pyrazinamide
rpsA 1833790 c.249T>A synonymous_variant 0.92 pyrazinamide
rpsA 1833805 c.264C>T synonymous_variant 0.91 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.9 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.91 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.92 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.93 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.94 pyrazinamide
rpsA 1833874 c.333T>G synonymous_variant 0.94 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.96 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.93 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.89 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.83 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.79 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.76 pyrazinamide
rpsA 1833982 c.441C>T synonymous_variant 0.73 pyrazinamide
rpsA 1833985 c.444G>T synonymous_variant 0.76 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.79 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.8 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.79 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.79 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.81 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.82 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.87 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.63 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 0.68 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 0.82 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.84 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.8 pyrazinamide
rpsA 1834426 c.885G>A synonymous_variant 0.8 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.84 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.83 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.87 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.89 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.83 pyrazinamide
rpsA 1834543 c.1002C>A synonymous_variant 0.8 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.8 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.76 pyrazinamide
rpsA 1834556 p.Ala339Gln missense_variant 0.75 pyrazinamide
rpsA 1834598 c.1057C>T synonymous_variant 0.78 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.74 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.73 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.73 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.8 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.84 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.85 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.84 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.82 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 0.74 pyrazinamide
rpsA 1834761 p.Phe407Tyr missense_variant 0.74 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.7 pyrazinamide
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.65 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 0.63 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.63 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 0.6 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.57 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.55 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.62 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.6 linezolid
tsnR 1853444 c.-162C>G upstream_gene_variant 0.56 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.46 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.39 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2064150 c.579T>C synonymous_variant 0.28 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064155 p.Val192Ile missense_variant 0.29 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
bacA 2064159 c.570A>G synonymous_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
bacA 2064165 c.564T>C synonymous_variant 0.3 streptomycin
kanamycin
capreomycin
amikacin
ndh 2102247 p.Val266Ile missense_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102248 c.795C>G synonymous_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102269 c.774C>G synonymous_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102275 c.768C>G synonymous_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102281 c.762C>G synonymous_variant 0.56 ethionamide
delamanid
isoniazid
ndh 2102302 c.741G>C synonymous_variant 0.56 ethionamide
delamanid
isoniazid
ndh 2102305 c.738T>G synonymous_variant 0.56 ethionamide
delamanid
isoniazid
ndh 2102308 c.735G>C synonymous_variant 0.56 ethionamide
delamanid
isoniazid
ndh 2102317 p.Glu242Asp missense_variant 0.47 ethionamide
delamanid
isoniazid
ndh 2102320 c.723G>C synonymous_variant 0.47 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 0.44 ethionamide
delamanid
isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.35 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.38 isoniazid Uncertain significance
katG 2155655 p.Lys153Gln missense_variant 0.38 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 0.38 isoniazid
katG 2155680 c.432G>A synonymous_variant 0.39 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.42 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.45 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.51 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.48 isoniazid
katG 2155735 c.374_377delGCATinsC missense_variant&disruptive_inframe_deletion 0.33 isoniazid
katG 2155752 c.360C>T synonymous_variant 0.32 isoniazid
katG 2155758 c.354C>T synonymous_variant 0.35 isoniazid
katG 2155765 p.His116Phe missense_variant 0.35 isoniazid
katG 2155782 c.330C>A synonymous_variant 0.35 isoniazid
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
kasA 2517917 c.-198G>T upstream_gene_variant 0.8 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.81 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.74 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.7 isoniazid
kasA 2517993 c.-122G>A upstream_gene_variant 0.68 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.42 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.58 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.63 isoniazid
kasA 2518150 c.36C>G synonymous_variant 0.65 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.67 isoniazid
kasA 2518156 c.42T>C synonymous_variant 0.67 isoniazid
kasA 2518159 c.45G>C synonymous_variant 0.67 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.74 isoniazid
kasA 2518180 c.66G>C synonymous_variant 0.77 isoniazid
kasA 2518187 p.Ile25Val missense_variant 0.79 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.79 isoniazid
kasA 2518193 p.Pro27Ala missense_variant 0.79 isoniazid
kasA 2518219 c.105T>C synonymous_variant 0.83 isoniazid
kasA 2518223 c.109T>C synonymous_variant 0.79 isoniazid
kasA 2518234 c.120G>A synonymous_variant 0.73 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.67 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.64 isoniazid
kasA 2518255 c.141A>G synonymous_variant 0.64 isoniazid
kasA 2518258 c.144C>T synonymous_variant 0.61 isoniazid
kasA 2518513 c.399C>G synonymous_variant 0.31 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.36 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.52 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.59 isoniazid
kasA 2518540 c.426T>G synonymous_variant 0.62 isoniazid
kasA 2518555 c.441C>G synonymous_variant 0.71 isoniazid
kasA 2518564 c.450C>G synonymous_variant 0.77 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.77 isoniazid
kasA 2518588 c.474T>G synonymous_variant 0.76 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.75 isoniazid
kasA 2518595 c.481_483delCGCinsAG frameshift_variant&missense_variant 0.73 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.72 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.72 isoniazid
kasA 2518618 c.504G>C synonymous_variant 0.73 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.71 isoniazid
kasA 2518636 c.522C>T synonymous_variant 0.61 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.56 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.5 isoniazid
kasA 2518811 p.Asp233Asn missense_variant 0.23 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.48 isoniazid
kasA 2518817 p.Asp235Asn missense_variant 0.26 isoniazid
kasA 2518822 c.708C>G synonymous_variant 0.35 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.52 isoniazid
kasA 2518828 c.714G>C synonymous_variant 0.23 isoniazid
kasA 2518839 p.Ala242Gly missense_variant 0.31 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.28 isoniazid
kasA 2518849 c.735G>C synonymous_variant 0.25 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.4 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.62 isoniazid
kasA 2518867 c.753G>A synonymous_variant 0.27 isoniazid
kasA 2518873 c.759C>T synonymous_variant 0.28 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.56 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.45 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.57 isoniazid
kasA 2519143 c.1029G>C synonymous_variant 0.64 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 0.67 isoniazid
kasA 2519158 c.1044C>A synonymous_variant 0.73 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.69 isoniazid
kasA 2519182 c.1068G>C synonymous_variant 0.72 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 0.71 isoniazid
kasA 2519188 c.1074G>C synonymous_variant 0.72 isoniazid
kasA 2519194 c.1080G>C synonymous_variant 0.71 isoniazid
kasA 2519195 c.1081_1083delACGinsTA frameshift_variant&stop_gained 0.71 isoniazid
kasA 2519203 c.1089C>T synonymous_variant 0.67 isoniazid
kasA 2519224 c.1110C>A synonymous_variant 0.61 isoniazid
kasA 2519239 c.1125A>G synonymous_variant 0.45 isoniazid
kasA 2519248 c.1134C>T synonymous_variant 0.3 isoniazid
ahpC 2726579 c.387T>C synonymous_variant 0.41 isoniazid
ahpC 2726582 c.390G>C synonymous_variant 0.52 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 0.7 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 0.73 isoniazid
ahpC 2726612 c.420C>G synonymous_variant 0.75 isoniazid
ahpC 2726633 c.441C>G synonymous_variant 0.78 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.79 isoniazid
ahpC 2726648 c.456T>C synonymous_variant 0.79 isoniazid
ahpC 2726657 c.465A>C synonymous_variant 0.79 isoniazid Not assoc w R - Interim
ahpC 2726669 c.477T>C synonymous_variant 0.74 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.7 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.66 isoniazid
ahpC 2726693 c.501C>G synonymous_variant 0.48 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.4 isoniazid
folC 2746642 c.957T>C synonymous_variant 0.63 para-aminosalicylic_acid
folC 2746651 c.948T>C synonymous_variant 0.69 para-aminosalicylic_acid
folC 2746663 c.936T>C synonymous_variant 0.69 para-aminosalicylic_acid
folC 2746666 c.933C>G synonymous_variant 0.69 para-aminosalicylic_acid
folC 2746677 p.Ser308Ala missense_variant 0.65 para-aminosalicylic_acid
folC 2746678 c.921T>G synonymous_variant 0.65 para-aminosalicylic_acid
folC 2746684 c.915C>G synonymous_variant 0.67 para-aminosalicylic_acid
folC 2746687 c.912C>G synonymous_variant 0.67 para-aminosalicylic_acid
folC 2746690 p.Val303Ala missense_variant 0.69 para-aminosalicylic_acid
folC 2746693 c.906G>C synonymous_variant 0.7 para-aminosalicylic_acid
folC 2746714 c.885T>C synonymous_variant 0.74 para-aminosalicylic_acid
folC 2746728 c.871T>C synonymous_variant 0.66 para-aminosalicylic_acid
folC 2746730 p.Tyr290Phe missense_variant 0.68 para-aminosalicylic_acid
folC 2746744 c.853_855delGTTinsCC frameshift_variant&missense_variant 0.48 para-aminosalicylic_acid
Rv2477c 2782414 p.Asp543Glu missense_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782419 p.Val542Ile missense_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782432 c.1611G>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782453 c.1590C>T synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782459 c.1584C>T synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782462 c.1581C>T synonymous_variant 0.76 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 p.Asp516Glu missense_variant 0.78 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782501 c.1542T>C synonymous_variant 0.79 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782525 c.1518C>T synonymous_variant 0.78 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 0.71 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>T synonymous_variant 0.62 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>G synonymous_variant 0.48 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783005 c.1038C>T synonymous_variant 0.52 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.5 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.44 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783116 c.927T>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783155 c.888C>G synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 0.63 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783185 c.858G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Val missense_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 0.62 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783347 c.696C>A synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783356 c.687C>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783377 c.666C>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783497 c.544_546delTTGinsCC frameshift_variant&missense_variant 0.78 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783502 c.541T>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783539 c.504G>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783557 c.486T>C synonymous_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>G synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783568 p.Asn159His missense_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>C synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783575 c.468G>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 0.65 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783634 p.Leu137Ile missense_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.51 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783695 c.348C>T synonymous_variant 0.36 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783839 c.204C>G synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783856 p.Phe63Ile missense_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783877 p.Lys56Gln missense_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>G synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783901 c.142T>C synonymous_variant 0.33 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.35 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.35 capreomycin
Rv2681 2996443 c.-296T>C upstream_gene_variant 0.39 capreomycin
Rv2680 2996446 c.342A>G synonymous_variant 0.41 capreomycin Not assoc w R - Interim
Rv2752c 3064980 c.1212C>G synonymous_variant 0.52 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064998 c.1194A>C synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065007 c.1185G>C synonymous_variant 0.55 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065028 c.1164G>T synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065031 c.1161G>C synonymous_variant 0.57 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065048 c.1144C>T synonymous_variant 0.45 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065064 c.1128G>C synonymous_variant 0.48 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>G synonymous_variant 0.45 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066269 c.-78A>C upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066270 c.-79G>A upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066274 c.-83A>T upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066276 c.-85G>C upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066279 c.-88A>G upstream_gene_variant 0.39 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066287 c.-96G>C upstream_gene_variant 0.35 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066288 c.-97G>A upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066302 c.-111C>A upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066303 c.-112C>G upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066313 c.-122T>C upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066315 c.-124C>A upstream_gene_variant 0.41 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066320 c.-129A>T upstream_gene_variant 0.42 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066336 c.-145C>G upstream_gene_variant 0.37 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyA 3073839 c.633T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.79 para-aminosalicylic_acid
thyA 3073868 p.Thr202Ala missense_variant 0.2 para-aminosalicylic_acid
thyA 3073872 c.600C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3073888 p.Ser195Glu missense_variant 0.73 para-aminosalicylic_acid
thyA 3073890 c.580_582delTTGinsCC frameshift_variant&missense_variant 0.73 para-aminosalicylic_acid
thyA 3073893 c.579C>A synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 0.72 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.75 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 0.68 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.63 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.6 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3073980 c.492C>T synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 0.61 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3073992 c.478_480delAGCinsTCG synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 0.55 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.57 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.5 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 0.49 para-aminosalicylic_acid
thyA 3074376 p.Gln32His missense_variant 0.39 para-aminosalicylic_acid
thyA 3074387 p.Leu29Val missense_variant 0.39 para-aminosalicylic_acid
thyA 3074397 c.75A>C synonymous_variant 0.33 para-aminosalicylic_acid
thyA 3074418 c.54A>G synonymous_variant 0.33 para-aminosalicylic_acid
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine
ald 3087257 c.438T>G synonymous_variant 0.42 cycloserine
ald 3087272 c.453A>C synonymous_variant 0.42 cycloserine
ald 3087274 p.Thr152Ser missense_variant 0.39 cycloserine
ald 3087278 p.Gln153His missense_variant 0.39 cycloserine
ald 3087281 c.462G>C synonymous_variant 0.4 cycloserine
ald 3087284 c.465C>G synonymous_variant 0.4 cycloserine
ald 3087290 c.471T>C synonymous_variant 0.44 cycloserine
ald 3087311 c.492C>G synonymous_variant 0.48 cycloserine
ald 3087314 c.495C>G synonymous_variant 0.46 cycloserine
ald 3087317 c.498C>G synonymous_variant 0.48 cycloserine
ald 3087319 p.Glu167Ala missense_variant 0.48 cycloserine
ald 3087323 c.504G>C synonymous_variant 0.48 cycloserine
ald 3087335 c.516G>C synonymous_variant 0.5 cycloserine
ald 3087346 p.Ala176Gly missense_variant 0.46 cycloserine
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0 pyrazinamide Not assoc w R
lpqB 3625078 c.-168G>C upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Lys missense_variant 0.82 bedaquiline
rifampicin
lpqB 3625117 c.-207T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625122 c.-212C>A upstream_gene_variant 0.77 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.76 bedaquiline
rifampicin
lpqB 3625129 c.-219C>T upstream_gene_variant 0.76 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625135 c.-225A>T upstream_gene_variant 0.73 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
lpqB 3625144 c.-234G>A upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3625149 p.Val489Ile missense_variant 0.73 bedaquiline
rifampicin
lpqB 3625161 c.-251T>C upstream_gene_variant 0.67 bedaquiline
rifampicin
lpqB 3625168 c.-258G>T upstream_gene_variant 0.64 bedaquiline
rifampicin
lpqB 3625183 c.-273G>T upstream_gene_variant 0.41 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.55 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.62 bedaquiline
rifampicin
lpqB 3625246 c.-336G>A upstream_gene_variant 0.61 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.67 bedaquiline
rifampicin
lpqB 3625258 c.-348G>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.69 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrB 3625291 p.Glu441Asp missense_variant 0.71 bedaquiline
rifampicin
lpqB 3625312 c.-402G>C upstream_gene_variant 0.69 bedaquiline
rifampicin
lpqB 3625336 c.-426C>T upstream_gene_variant 0.6 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.56 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.51 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625357 c.-447T>C upstream_gene_variant 0.41 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.48 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625579 c.-669A>C upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625585 c.-675G>C upstream_gene_variant 0.5 bedaquiline
rifampicin
lpqB 3625591 c.-681C>T upstream_gene_variant 0.54 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
lpqB 3625602 c.-692T>C upstream_gene_variant 0.54 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 0.62 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 0.79 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625669 c.-759G>C upstream_gene_variant 0.84 bedaquiline
rifampicin
lpqB 3625683 c.-773C>T upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625687 c.927G>A synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625690 c.-780T>G upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625702 c.-792C>T upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625723 c.-813C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3625729 c.885A>G synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625747 c.867G>C synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.85 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625766 p.Ser283His missense_variant 0.81 bedaquiline
rifampicin
lpqB 3625795 c.-885G>C upstream_gene_variant 0.78 bedaquiline
rifampicin
lpqB 3625798 c.-888G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3625804 c.808_810delAGGinsCC frameshift_variant&missense_variant 0.7 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626284 c.330T>G synonymous_variant 0.47 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626296 c.316_318delCTTinsTG frameshift_variant&synonymous_variant 0.5 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626308 c.306T>C synonymous_variant 0.56 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626314 c.300G>C synonymous_variant 0.56 bedaquiline
rifampicin
mtrB 3626317 c.297A>G synonymous_variant 0.6 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626323 c.291G>C synonymous_variant 0.64 bedaquiline
rifampicin
mtrB 3626336 p.Asn93Gly missense_variant 0.53 bedaquiline
rifampicin
mtrB 3626362 c.252A>G synonymous_variant 0.47 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626365 c.249G>C synonymous_variant 0.45 bedaquiline
rifampicin
mtrB 3626368 p.Glu82Asp missense_variant 0.43 bedaquiline
rifampicin
mtrB 3626377 p.Asp79Glu missense_variant 0.4 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3626702 c.-89G>C upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 0.43 bedaquiline
rifampicin
mtrB 3626714 c.-101G>C upstream_gene_variant 0.43 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.55 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrA 3626741 c.609C>G synonymous_variant 0.69 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 0.82 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3626795 c.-182C>T upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.53 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.44 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 0.39 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.35 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 0.67 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3627092 c.-479C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.78 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.76 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627131 c.-518C>G upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3627137 c.211_213delTTGinsCC frameshift_variant&missense_variant 0.7 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 0.73 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627215 c.-602G>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrB 3627230 c.-617G>A upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3627233 c.-620T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.73 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627263 c.-650C>T upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 0.45 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCC frameshift_variant&missense_variant 0.42 bedaquiline
rifampicin
mtrA 3627305 c.43_45delGCTinsCG frameshift_variant&synonymous_variant 0.44 bedaquiline
rifampicin
mtrA 3627311 c.39C>T synonymous_variant 0.48 bedaquiline Not assoc w R - Interim
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.47 bedaquiline
rifampicin
mtrB 3627320 c.-707C>T upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3627325 c.-712T>C upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.44 bedaquiline
rifampicin
alr 3840719 c.702A>G synonymous_variant 1.0 cycloserine
rpoA 3877542 c.966C>T synonymous_variant 0.58 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 0.58 rifampicin
rpoA 3877554 c.954G>C synonymous_variant 0.58 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3877565 c.942delC frameshift_variant 0.57 rifampicin
rpoA 3877568 p.Ser314Arg missense_variant 0.57 rifampicin
rpoA 3877569 c.939G>T synonymous_variant 0.57 rifampicin
rpoA 3877572 c.935dupC frameshift_variant 0.6 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>A synonymous_variant 0.74 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 0.83 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 0.82 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.81 rifampicin
rpoA 3877677 c.831G>T synonymous_variant 0.81 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.79 rifampicin
rpoA 3877737 c.771G>A synonymous_variant 0.76 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 0.75 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877803 c.705G>C synonymous_variant 0.87 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.82 rifampicin
rpoA 3877875 c.633T>G synonymous_variant 0.82 rifampicin
rpoA 3877881 c.627G>A synonymous_variant 0.83 rifampicin
rpoA 3877884 c.624G>C synonymous_variant 0.82 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 0.83 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.84 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 0.69 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 0.67 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.61 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoA 3878010 c.498C>G synonymous_variant 0.36 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.57 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878175 c.333G>T synonymous_variant 0.75 rifampicin
rpoA 3878184 c.324C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 0.76 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoA 3878244 c.264G>A synonymous_variant 0.8 rifampicin
rpoA 3878250 c.258C>G synonymous_variant 0.74 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 0.73 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.74 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.71 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.66 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>T synonymous_variant 0.56 rifampicin
rpoA 3878322 c.186A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>G synonymous_variant 0.38 rifampicin
rpoA 3878337 c.171T>C synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.41 rifampicin
rpoA 3878785 c.-278T>G upstream_gene_variant 0.45 rifampicin
rpoA 3878797 c.-290G>C upstream_gene_variant 0.44 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.48 rifampicin
rpoA 3878813 c.-307_-306delCAinsGT upstream_gene_variant 0.5 rifampicin
rpoA 3878821 c.-315_-314delTGinsAT upstream_gene_variant 0.47 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.47 rifampicin
rpoA 3878830 c.-323G>C upstream_gene_variant 0.47 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.45 rifampicin
rpoA 3878839 c.-332C>G upstream_gene_variant 0.53 rifampicin
rpoA 3878843 c.-337_-336delCGinsAA upstream_gene_variant 0.53 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.64 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.64 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 0.55 rifampicin
rpoA 3878886 c.-379G>A upstream_gene_variant 0.52 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 0.58 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 0.58 rifampicin
rpoA 3878896 c.-389G>C upstream_gene_variant 0.6 rifampicin
rpoA 3878899 c.-392C>T upstream_gene_variant 0.6 rifampicin
rpoA 3878908 c.-403_-401delAACinsCTG upstream_gene_variant 0.57 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.6 rifampicin Uncertain significance
rpoA 3878938 c.-431T>G upstream_gene_variant 0.56 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.5 rifampicin Uncertain significance
rpoA 3879061 c.-554C>T upstream_gene_variant 0.38 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 0.39 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.42 rifampicin
rpoA 3879082 c.-575C>G upstream_gene_variant 0.45 rifampicin
rpoA 3879088 c.-583_-581delACAinsTG upstream_gene_variant 0.43 rifampicin
rpoA 3879091 c.-584C>T upstream_gene_variant 0.46 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.53 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.54 rifampicin
rpoA 3879124 c.-618_-617delTGinsGC upstream_gene_variant 0.53 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.54 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.53 rifampicin
rpoA 3879151 c.-644C>T upstream_gene_variant 0.46 rifampicin
ddn 3986636 c.-208C>T upstream_gene_variant 0.77 delamanid
pretomanid
ddn 3986642 c.-202C>T upstream_gene_variant 0.75 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.73 delamanid
pretomanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.65 delamanid
pretomanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.6 delamanid
pretomanid
ddn 3986681 c.-163C>G upstream_gene_variant 0.6 delamanid
pretomanid
ddn 3986687 c.-157C>T upstream_gene_variant 0.58 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.56 delamanid
pretomanid
ddn 3986696 c.-148G>T upstream_gene_variant 0.55 delamanid
pretomanid
ddn 3986699 c.-145C>G upstream_gene_variant 0.56 delamanid
pretomanid
ddn 3986714 c.-130C>G upstream_gene_variant 0.32 delamanid
pretomanid
clpC1 4038271 p.Pro812Ala missense_variant 0.34 pyrazinamide
clpC1 4038272 c.2431_2433delGGTinsAC frameshift_variant&missense_variant 0.33 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.33 pyrazinamide
clpC1 4038287 c.2418C>T synonymous_variant 0.58 pyrazinamide Not assoc w R
clpC1 4038293 c.2412G>C synonymous_variant 0.42 pyrazinamide
clpC1 4038302 c.2403C>G synonymous_variant 0.44 pyrazinamide
clpC1 4038308 c.2395_2397delGTGinsCC frameshift_variant&missense_variant 0.45 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.42 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.42 pyrazinamide
clpC1 4038320 c.2385G>T synonymous_variant 0.42 pyrazinamide
clpC1 4038325 p.Val794Ile missense_variant 0.45 pyrazinamide
clpC1 4038335 c.2370C>G synonymous_variant 0.44 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.62 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.66 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.66 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.68 pyrazinamide
clpC1 4038374 c.2331C>T synonymous_variant 0.66 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.59 pyrazinamide
clpC1 4038392 c.2313C>G synonymous_variant 0.59 pyrazinamide
clpC1 4038395 c.2310C>G synonymous_variant 0.59 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 0.59 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCC frameshift_variant&missense_variant 0.59 pyrazinamide
clpC1 4038407 c.2298G>C synonymous_variant 0.57 pyrazinamide
clpC1 4038416 c.2289C>G synonymous_variant 0.62 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.65 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.53 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 0.62 pyrazinamide
clpC1 4038509 c.2196C>T synonymous_variant 0.67 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.77 pyrazinamide
clpC1 4038587 c.2116_2118delCGCinsAG frameshift_variant&missense_variant 0.79 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.8 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.73 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.69 pyrazinamide
clpC1 4038650 c.2055C>T synonymous_variant 0.62 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.62 pyrazinamide
clpC1 4038657 p.Lys683Pro missense_variant 0.59 pyrazinamide
clpC1 4038659 c.2046C>G synonymous_variant 0.61 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.64 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.69 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.78 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.76 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.77 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.82 pyrazinamide
clpC1 4038749 c.1956C>A synonymous_variant 0.84 pyrazinamide
clpC1 4038755 c.1950G>T synonymous_variant 0.85 pyrazinamide
clpC1 4038764 c.1941C>G synonymous_variant 0.84 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.84 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.85 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.89 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.88 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.84 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>C synonymous_variant 0.74 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.7 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.69 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.68 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.68 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.72 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.72 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 0.73 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.74 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.73 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039025 c.1680C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.79 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.78 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4039082 c.1623C>T synonymous_variant 0.74 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.74 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.77 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.76 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.74 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.7 pyrazinamide
clpC1 4039193 c.1512C>G synonymous_variant 0.68 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.64 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.64 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.6 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.57 pyrazinamide
clpC1 4039259 c.1446G>A synonymous_variant 0.44 pyrazinamide
clpC1 4039268 c.1437C>T synonymous_variant 0.43 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.43 pyrazinamide Not assoc w R - Interim
clpC1 4039277 c.1428C>G synonymous_variant 0.44 pyrazinamide
clpC1 4039280 c.1425G>C synonymous_variant 0.44 pyrazinamide
clpC1 4039286 c.1419T>C synonymous_variant 0.5 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.5 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.56 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.59 pyrazinamide
clpC1 4039316 c.1389G>A synonymous_variant 0.52 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.52 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 0.52 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.52 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.58 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.58 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.59 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.63 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.64 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.65 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.7 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.75 pyrazinamide
clpC1 4039466 c.1239T>G synonymous_variant 0.83 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.85 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.81 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039576 p.Ala377Ser missense_variant 0.83 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.85 pyrazinamide
clpC1 4039619 c.1086G>T synonymous_variant 0.85 pyrazinamide
clpC1 4039622 c.1083C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039628 c.1077C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.81 pyrazinamide
clpC1 4039733 c.972G>A synonymous_variant 0.78 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.78 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.73 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039756 c.949C>T synonymous_variant 0.67 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.67 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.66 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039783 c.922C>T synonymous_variant 0.7 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.71 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.65 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.63 pyrazinamide
clpC1 4039823 c.882T>G synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.64 pyrazinamide
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 0.65 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.65 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.77 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039874 c.831C>T synonymous_variant 0.77 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.81 pyrazinamide
clpC1 4039901 c.804C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
clpC1 4039922 c.783C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039925 c.780C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039946 c.759A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.81 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.82 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039988 c.717C>G synonymous_variant 0.79 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.79 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.74 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.72 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.74 pyrazinamide
clpC1 4040048 c.657C>T synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.76 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.75 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.79 pyrazinamide
clpC1 4040123 c.582G>A synonymous_variant 0.8 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.68 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.73 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>C synonymous_variant 0.72 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.62 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.61 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.62 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.62 pyrazinamide
clpC1 4040214 p.Ser164Asn missense_variant 0.62 pyrazinamide
clpC1 4040221 p.Ser162Ala missense_variant 0.68 pyrazinamide
clpC1 4040225 c.480A>T synonymous_variant 0.69 pyrazinamide
clpC1 4040228 c.477G>T synonymous_variant 0.73 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.77 pyrazinamide
clpC1 4040252 c.453C>G synonymous_variant 0.75 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.74 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4040270 c.435C>T synonymous_variant 0.71 pyrazinamide
clpC1 4040273 c.432T>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.429C>G synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040279 c.426C>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.73 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.79 pyrazinamide
clpC1 4040312 c.393G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.77 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.76 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.76 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.74 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.72 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.73 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 0.72 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.71 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.69 pyrazinamide Not assoc w R - Interim
clpC1 4040408 c.297C>T synonymous_variant 0.46 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4040414 c.291G>A synonymous_variant 0.38 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.58 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.63 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.59 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 0.63 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>A synonymous_variant 0.71 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.71 pyrazinamide
clpC1 4040537 c.168G>C synonymous_variant 0.73 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.71 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.61 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.52 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.52 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.35 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.38 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.52 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.52 pyrazinamide
clpC1 4040690 c.15T>C synonymous_variant 0.52 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 0.5 pyrazinamide
clpC1 4040696 c.9A>G synonymous_variant 0.48 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.48 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 0.58 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.66 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.7 pyrazinamide
panD 4044210 c.72C>G synonymous_variant 0.67 pyrazinamide
panD 4044213 c.69C>A synonymous_variant 0.67 pyrazinamide
panD 4044225 c.57C>T synonymous_variant 0.65 pyrazinamide
panD 4044231 p.Cys17Lys missense_variant 0.65 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 0.65 pyrazinamide
panD 4044270 c.12G>A synonymous_variant 0.62 pyrazinamide
panD 4044287 c.-6A>G upstream_gene_variant 0.43 pyrazinamide
glpK 4138514 c.1242A>C synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 c.1239A>G synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138532 c.1224G>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138562 c.1194G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138583 c.1173G>C synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138589 c.1167C>G synonymous_variant 0.68 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 0.66 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138604 c.1150_1152delTTGinsCC frameshift_variant&missense_variant 0.48 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138607 c.1149G>T synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138619 c.1137C>G synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138628 c.1128T>C synonymous_variant 0.27 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138661 c.1095T>C synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138679 c.1075_1077delATGinsGC frameshift_variant&missense_variant 0.51 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138694 p.Pro354Glu missense_variant 0.56 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138706 c.1050C>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138712 c.1044G>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.53 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 c.1035G>A synonymous_variant 0.55 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138727 c.1029C>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138730 c.1026C>T synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.997_999delCTAinsTG frameshift_variant&synonymous_variant 0.51 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138775 c.981C>T synonymous_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138781 c.975G>C synonymous_variant 0.39 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138787 c.969C>T synonymous_variant 0.35 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138796 c.960A>G synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139576 c.180G>C synonymous_variant 0.47 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139579 c.177C>T synonymous_variant 0.44 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139588 c.168G>C synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139594 c.162C>A synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139597 c.159C>G synonymous_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Lys missense_variant 0.38 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139603 c.153C>G synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139637 p.Ala40Gly missense_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139639 c.115_117delGTGinsAC frameshift_variant&missense_variant 0.59 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139652 p.His35Gly missense_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139657 c.99T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139672 c.84C>G synonymous_variant 0.46 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139693 c.63C>T synonymous_variant 0.44 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139699 c.57C>G synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139705 c.51A>C synonymous_variant 0.35 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239486 c.-377T>C upstream_gene_variant 0.48 ethambutol
embC 4239512 c.-351G>C upstream_gene_variant 0.55 ethambutol Uncertain significance
embC 4239521 c.-342C>T upstream_gene_variant 0.57 ethambutol
embC 4239526 c.-337_-336delGGinsAC upstream_gene_variant 0.59 ethambutol
embC 4239533 c.-330T>C upstream_gene_variant 0.61 ethambutol
embC 4239540 c.-323_-321delTTGinsCC upstream_gene_variant 0.55 ethambutol
embC 4239545 c.-318G>C upstream_gene_variant 0.55 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 0.55 ethambutol
embC 4239566 c.-297G>C upstream_gene_variant 0.5 ethambutol
embC 4240717 c.855T>C synonymous_variant 0.4 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.54 ethambutol Not assoc w R - Interim
embC 4240736 p.Ser292Ala missense_variant 0.58 ethambutol
embC 4240759 c.897C>G synonymous_variant 0.72 ethambutol
embC 4240765 c.903C>G synonymous_variant 0.72 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.71 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.73 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.74 ethambutol
embC 4240795 c.933C>G synonymous_variant 0.74 ethambutol
embC 4240819 c.957A>C synonymous_variant 0.65 ethambutol
embC 4240822 c.960C>G synonymous_variant 0.62 ethambutol
embC 4240825 c.963G>A synonymous_variant 0.61 ethambutol
embC 4240826 p.Ala322Ser missense_variant 0.6 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.6 ethambutol
embC 4240858 c.996G>A synonymous_variant 0.47 ethambutol
embC 4240859 c.997C>T synonymous_variant 0.44 ethambutol
embC 4240867 c.1005T>A synonymous_variant 0.4 ethambutol
embC 4240870 c.1008T>C synonymous_variant 0.43 ethambutol
embC 4240880 p.Ala340His missense_variant 0.28 ethambutol
embC 4240885 c.1023T>C synonymous_variant 0.29 ethambutol
embC 4240886 p.Ile342Val missense_variant 0.29 ethambutol
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4247996 p.Ala495Phe missense_variant 0.52 ethambutol
embB 4248008 c.1495_1497delCTGinsAC frameshift_variant&missense_variant 0.59 ethambutol
embB 4248011 p.Ser500Ala missense_variant 0.62 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.71 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.7 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.69 ethambutol
embB 4248052 c.1539G>C synonymous_variant 0.7 ethambutol Not assoc w R - Interim
embB 4248057 p.Ser515Asn missense_variant 0.71 ethambutol
embB 4248063 p.Ala517Glu missense_variant 0.74 ethambutol
embB 4248070 c.1557T>C synonymous_variant 0.69 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.67 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.59 ethambutol
embB 4248106 c.1593C>G synonymous_variant 0.5 ethambutol
embB 4248109 c.1596C>G synonymous_variant 0.45 ethambutol
embB 4248118 c.1605T>A synonymous_variant 0.32 ethambutol
embB 4248122 c.1609C>T synonymous_variant 0.32 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.29 ethambutol
embB 4248133 c.1620C>A synonymous_variant 0.27 ethambutol
embB 4248241 c.1728C>G synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embB 4248242 p.Val577Ile missense_variant 0.53 ethambutol
embB 4248248 p.Phe579Leu missense_variant 0.58 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.59 ethambutol
embB 4248257 p.Met582Val missense_variant 0.57 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.67 ethambutol
embB 4248280 c.1767C>G synonymous_variant 0.67 ethambutol
embB 4248283 c.1770C>G synonymous_variant 0.69 ethambutol
embB 4248295 c.1782C>T synonymous_variant 0.64 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.64 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.6 ethambutol
embB 4248325 c.1812G>C synonymous_variant 0.65 ethambutol
embB 4248334 c.1821C>G synonymous_variant 0.65 ethambutol
embB 4248341 p.Thr610Ala missense_variant 0.59 ethambutol
embB 4249469 p.Leu986Met missense_variant 0.45 ethambutol
embB 4249480 c.2967G>C synonymous_variant 0.5 ethambutol
embB 4249483 c.2970C>G synonymous_variant 0.5 ethambutol
embB 4249486 c.2973T>C synonymous_variant 0.5 ethambutol
embB 4249487 c.2974T>C synonymous_variant 0.5 ethambutol
embB 4249492 c.2979C>G synonymous_variant 0.49 ethambutol
embB 4249501 c.2988C>T synonymous_variant 0.46 ethambutol
embB 4249525 c.3012T>C synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4249529 p.Ile1006Val missense_variant 0.49 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 0.5 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 0.5 ethambutol
embB 4249540 c.3027C>T synonymous_variant 0.5 ethambutol
embB 4249558 c.3045A>T synonymous_variant 0.33 ethambutol
ethA 4326280 c.1194G>T synonymous_variant 0.64 ethionamide
ethA 4326304 c.1170C>G synonymous_variant 0.59 ethionamide
ethA 4326307 c.1167C>A synonymous_variant 0.59 ethionamide
ethA 4326310 c.1164T>C synonymous_variant 0.59 ethionamide
ethA 4326329 p.Tyr382Phe missense_variant 0.68 ethionamide
ethA 4326331 c.1143C>G synonymous_variant 0.68 ethionamide
ethA 4326343 p.Ile377Met missense_variant 0.68 ethionamide
ethA 4326347 p.Gly376His missense_variant 0.68 ethionamide
ethA 4326351 p.Ser375Thr missense_variant 0.66 ethionamide
ethA 4326352 c.1122T>G synonymous_variant 0.68 ethionamide
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
gid 4408156 p.Leu16Arg missense_variant 1.0 streptomycin Not assoc w R