TB-Profiler result

Run: ERR2026695
Summary

Run ID: ERR2026695

Sample name:

Date: 2024-04-16T09:33:48.829361

Number of reads: 8335603

Percentage reads mapped: 58.62

Median coverage: 68.0

Strain: La1.7.1;M.canetti;lineage4.2;lineage6.2;lineage6.3

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.2 West-Africa 2 RD702 0.45
lineage6.3 West-Africa 2 RD702 0.32
lineage4.2 Euro-American None 0.67
lineage4.6.4 Euro-American None 0.59
lineage6.1.3 West-Africa 2 RD702 0.15
lineage1.1.1 Indo-Oceanic RD239 0.12
lineage1.1.3.1 Indo-Oceanic RD239 0.09
La1.7.1 M.bovis None 0.23
M.canetti M.canetti None 0.33
lineage4.6.2.1 Euro-American RD726 0.1
La1 M.bovis None 0.69
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG c.1246_1248delATCinsTG Assoc w R High-level resistance
c.1144_1146delCTCinsAA Assoc w R High-level resistance
p.Ala379Val Uncertain significance Mutation from literature
ethambutol embB p.Tyr384Asn Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide ethA c.877_879delTTGinsCA Assoc w R
c.814_816delCTAinsTG Assoc w R
c.796_798delAGCinsGA Assoc w R
c.751_753delAGCinsGA Assoc w R
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.139_141delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.340_342delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.355_357delGAGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.412_414delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.421_423delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.648_658delTGCCGCTGACC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.663_664delCGinsAACAACCGCAATA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.904_906delACAinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.973_975delCAGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.751_753delTTGinsCT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1144_1146delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1270_1272delCTGinsTT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1669_1671delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1742delT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1746_1747insC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2158_2160delGTCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1099_1101delGACinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1237_1239delGACinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490921 c.139_141delCAGinsGA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.98 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491122 c.340_342delATCinsGT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491137 c.355_357delGAGinsCA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491194 c.412_414delCTAinsTG frameshift_variant&stop_gained 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491203 c.421_423delCAGinsGA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491428 c.648_658delTGCCGCTGACC frameshift_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491445 c.663_664delCGinsAACAACCGCAATA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491686 c.904_906delACAinsGC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491755 c.973_975delCAGinsGA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303681 c.751_753delTTGinsCT frameshift_variant&synonymous_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304074 c.1144_1146delGCCinsTG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304200 c.1270_1272delCTGinsTT frameshift_variant&synonymous_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304599 c.1669_1671delATCinsGT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304671 c.1742delT frameshift_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304676 c.1746_1747insC frameshift_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305088 c.2158_2160delGTCinsAT frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
katG 2154864 c.1246_1248delATCinsTG frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
katG 2154966 c.1144_1146delCTCinsAA frameshift_variant&missense_variant 1.0 isoniazid Assoc w R High-level resistance
katG 2154976 p.Ala379Val missense_variant 1.0 isoniazid Uncertain significance Mutation from literature
fbiB 3642633 c.1099_1101delGACinsCA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642771 c.1237_1239delGACinsCG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247663 p.Tyr384Asn missense_variant 1.0 ethambutol Mutation from literature
ethA 4326595 c.877_879delTTGinsCA frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4326658 c.814_816delCTAinsTG frameshift_variant&synonymous_variant 1.0 ethionamide Assoc w R
ethA 4326676 c.796_798delAGCinsGA frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
ethA 4326721 c.751_753delAGCinsGA frameshift_variant&missense_variant 1.0 ethionamide Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 504 c.504T>C synonymous_variant 1.0 isoniazid
dnaA 510 c.510T>C synonymous_variant 1.0 isoniazid
dnaA 519 c.519C>G synonymous_variant 1.0 isoniazid Not assoc w R
dnaA 522 c.522T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 1.0 isoniazid
dnaA 528 c.528G>C synonymous_variant 1.0 isoniazid
dnaA 534 c.534T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 540 c.540C>A synonymous_variant 1.0 isoniazid
dnaA 552 c.552G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 558 c.558G>A synonymous_variant 1.0 isoniazid
dnaA 564 c.564C>G synonymous_variant 1.0 isoniazid
dnaA 568 c.568_570delGCCinsAT frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 571 c.571T>C synonymous_variant 1.0 isoniazid
dnaA 582 c.582A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 585 c.585A>G synonymous_variant 1.0 isoniazid
dnaA 597 c.597C>T synonymous_variant 1.0 isoniazid
dnaA 600 c.600T>C synonymous_variant 1.0 isoniazid
dnaA 609 c.609C>A synonymous_variant 1.0 isoniazid
dnaA 612 c.612G>T synonymous_variant 1.0 isoniazid
dnaA 633 c.633T>C synonymous_variant 1.0 isoniazid
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 642 c.642G>A synonymous_variant 1.0 isoniazid
dnaA 645 c.645A>G synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 660 c.660G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 666 c.666C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>A synonymous_variant 0.99 isoniazid
dnaA 678 c.678A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 681 c.681G>T synonymous_variant 1.0 isoniazid
dnaA 693 c.693A>C synonymous_variant 1.0 isoniazid
dnaA 699 c.699G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 711 c.711C>G synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 753 c.753C>T synonymous_variant 1.0 isoniazid
dnaA 765 c.765G>A synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>C synonymous_variant 1.0 isoniazid
dnaA 783 c.783C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 801 c.801G>A synonymous_variant 1.0 isoniazid
dnaA 802 c.802C>T synonymous_variant 1.0 isoniazid
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 813 c.813C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 888 c.888C>G synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 903 c.903C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>G synonymous_variant 1.0 isoniazid
dnaA 912 c.912T>G synonymous_variant 1.0 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 933 c.933C>G synonymous_variant 1.0 isoniazid
dnaA 945 c.945G>A synonymous_variant 1.0 isoniazid
dnaA 954 c.954G>C synonymous_variant 1.0 isoniazid
dnaA 963 c.963C>G synonymous_variant 1.0 isoniazid
dnaA 966 c.966T>C synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>T synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1008 c.1008G>A synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 1.0 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 1.0 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 1.0 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 1.0 isoniazid
dnaA 1050 c.1050G>A synonymous_variant 1.0 isoniazid
dnaA 1059 c.1059C>G synonymous_variant 1.0 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 1.0 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1107 c.1107C>T synonymous_variant 1.0 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 1.0 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 1.0 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 1.0 isoniazid
dnaA 1134 c.1134G>T synonymous_variant 1.0 isoniazid
dnaA 1146 c.1146C>T synonymous_variant 1.0 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>C synonymous_variant 1.0 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1179 c.1179G>A synonymous_variant 1.0 isoniazid
dnaA 1182 c.1182G>T synonymous_variant 1.0 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 1.0 isoniazid
dnaA 1200 c.1200C>T synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1219 p.Asn407Gly missense_variant 1.0 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1281 c.1281C>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>C synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>T synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1317 c.1317A>G synonymous_variant 0.99 isoniazid
dnaA 1323 c.1323C>T synonymous_variant 0.99 isoniazid Not assoc w R - Interim
dnaA 1329 c.1329A>G synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>G synonymous_variant 1.0 isoniazid
dnaA 1365 c.1365C>T synonymous_variant 1.0 isoniazid
dnaA 1368 c.1368T>C synonymous_variant 1.0 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 1.0 isoniazid
dnaA 1374 c.1374G>A synonymous_variant 1.0 isoniazid
dnaA 1375 c.1375_1377delTTGinsCA frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.98 isoniazid
dnaA 1395 c.1395G>A synonymous_variant 1.0 isoniazid
dnaA 1401 c.1401C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1404 c.1404T>C synonymous_variant 1.0 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 1.0 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 1.0 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 1.0 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 1.0 isoniazid
dnaA 1449 c.1449G>A synonymous_variant 1.0 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
gyrB 6086 p.Thr283Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6103 c.864G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6205 c.966C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6320 p.Lys361Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6334 c.-968G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6352 c.1113C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6400 c.-902C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6409 c.-893A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6472 c.-830G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6484 c.-818A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6487 c.-815C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6491 p.Ile418Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6502 c.-800T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6535 c.-767C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6542 p.Ile435Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6563 c.1324C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6580 c.-722C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6583 c.1344G>A synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6589 c.-713G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6592 c.-710C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6646 c.-656C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6724 c.-578G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6764 c.-538C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6787 c.-515G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.99 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6823 c.-479G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6824 c.1585C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6865 c.-437G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6866 c.-436C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6877 c.-425G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6950 c.1711_1713delCTCinsTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6966 p.Ser576Thr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6970 p.Asp577Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6991 c.-311C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7009 c.-293G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7018 c.-284G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7027 c.-275G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7066 c.-236G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7072 c.-230G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7100 c.1861T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7120 c.-182T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>A upstream_gene_variant 0.99 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7159 c.1920C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7162 c.-140C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7189 c.-113C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7210 c.-92C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7508 c.207C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7538 c.237G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7580 c.279C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7587 c.286C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7673 c.372G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7700 c.399G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7721 c.420G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7725 c.424C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 7821 c.520C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7881 c.580C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7889 c.588G>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7911 p.Ala204Cys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 c.618G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7942 p.Glu214Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8144 c.843C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8186 c.885G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8204 c.903C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8231 c.930C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8234 c.933T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8240 c.939C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8279 c.978G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8282 c.981G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 c.1039_1041delGCGinsTC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8351 c.1050C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8354 c.1053G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8357 c.1056G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8393 c.1092T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8417 c.1116C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8426 c.1125G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8456 c.1155C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8540 c.1239C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8557 p.Ala419Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8570 c.1269G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8723 c.1422G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8731 p.Gly477Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8741 c.1440C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8816 c.1515C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8822 c.1521C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8885 c.1584C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8954 c.1653G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8993 c.1692C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9064 p.Ser588Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9077 c.1776C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9092 c.1791C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9104 c.1803C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9134 c.1833C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9265 p.Asp655Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9267 c.1966_1968delAACinsGA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9300 p.Ala667Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9329 c.2028C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9425 c.2124C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9446 c.2145C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9455 c.2154T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9458 c.2157A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9468 c.2167C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9483 c.2182_2184delTCAinsGG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9503 c.2202T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9506 c.2205C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9508 p.Ala736Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9521 c.2220C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9545 c.2244A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9548 c.2247T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9557 c.2256G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9558 p.Val753Ile missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 9566 c.2265C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9582 c.2281A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9597 c.2296T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9608 c.2307C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9617 c.2316C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9623 c.2322G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9641 c.2340C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9665 c.2364A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9719 c.2418G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
Rv0010c 13713 c.-155T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13717 c.-159T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13741 c.-183T>A upstream_gene_variant 1.0 isoniazid
Rv0010c 13771 c.-213T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13780 c.-222C>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13786 c.-228C>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13789 c.-231A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13792 c.-234G>T upstream_gene_variant 1.0 isoniazid
Rv0010c 13810 c.-254_-252delACAinsGG upstream_gene_variant 1.0 isoniazid
Rv0010c 13816 c.-258C>T upstream_gene_variant 1.0 isoniazid
Rv0010c 13822 c.-264C>T upstream_gene_variant 1.0 isoniazid
Rv0010c 13828 c.-272_-270delATTinsGC upstream_gene_variant 1.0 isoniazid
Rv0010c 13834 c.-276A>T upstream_gene_variant 1.0 isoniazid
Rv0010c 13843 c.-285T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13852 c.-294A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13860 c.-302A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13861 c.-303C>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13864 c.-306A>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13870 c.-312G>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13878 c.-320C>T upstream_gene_variant 1.0 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13903 c.-345A>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 1.0 isoniazid
fgd1 490887 c.105G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490926 c.144C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490965 c.183C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490984 p.Leu68Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490988 p.Leu69Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490990 c.208C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491052 c.270C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491070 c.288G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491100 c.318C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491151 c.369G>C synonymous_variant 0.99 clofazimine
pretomanid
delamanid
fgd1 491154 c.372G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491178 c.396G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491217 c.435T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491262 c.480C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491280 c.498C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491289 c.507C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491310 c.528C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491334 c.552C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491337 c.555C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491343 c.561C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491355 c.573C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491358 c.576C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491364 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491367 c.585G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491393 p.Thr204Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491409 c.627G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491415 c.633A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491418 c.636A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491453 p.Gly224Asp missense_variant 1.0 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
fgd1 491496 c.714C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491502 c.720G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491520 c.738C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491546 p.Thr255Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491561 p.His260Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491570 p.Asp263Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491590 p.Lys270Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 p.Asp273Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491622 c.840C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491667 c.885A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491694 c.912C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491703 c.921C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491712 p.Phe310Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491718 c.936A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491721 c.939A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491724 c.942A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491727 c.945T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491735 p.Arg318Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491742 c.960T>C synonymous_variant 1.0 clofazimine Not assoc w R
pretomanid
delamanid Not assoc w R - Interim
fgd1 491748 c.966G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491751 c.969C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491758 p.Ser326Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491769 c.987A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491775 c.993G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575521 c.174A>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575545 c.198C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575561 p.Met72Val missense_variant 1.0 ethionamide
isoniazid
mshA 575578 c.231G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575581 c.234C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575588 p.Arg81Lys missense_variant 1.0 ethionamide
isoniazid
mshA 575596 c.249C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575605 c.258G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575611 c.264C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575629 c.282A>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575635 c.288A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575638 c.291T>C synonymous_variant 0.99 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575665 c.318G>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575680 c.333C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575692 c.345G>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575695 c.348C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575732 c.385_387delCTTinsTG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.98 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575786 p.Tyr147His missense_variant 1.0 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575824 c.477T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575860 c.513G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575863 c.516G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575872 c.525C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575881 c.534C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575915 p.Asp190Asn missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575920 c.573C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575923 c.576C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 1.0 ethionamide
isoniazid
mshA 575929 c.582C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575947 c.600G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575950 c.603C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575977 c.630G>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575984 c.637_639delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 576007 c.660A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576012 p.Arg222Lys missense_variant 1.0 ethionamide
isoniazid
mshA 576017 p.Val224Leu missense_variant 1.0 ethionamide
isoniazid
mshA 576022 c.675T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576026 p.Leu227Ile missense_variant 1.0 ethionamide
isoniazid
mshA 576031 c.684T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576032 p.Gly229Arg missense_variant 1.0 ethionamide
isoniazid
mshA 576037 c.690C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576046 c.699A>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576049 c.702A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576058 c.711G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 576061 c.714C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 576076 c.729T>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 619501 c.-390C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619510 c.-381G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619513 c.-378G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619527 c.-364C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620106 p.Phe72Leu missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620112 c.222A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620126 p.Gly79Ala missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620130 c.240G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620139 c.249C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620141 p.Ala84Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620145 c.255T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620160 c.270A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620161 c.271C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620169 c.279G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620173 p.Val95Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620179 c.289C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620208 c.318G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620236 c.346C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 p.Leu119Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620275 c.385C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620296 c.406_408delCCGinsTA frameshift_variant&stop_gained 0.98 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620328 c.438G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620361 c.471C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620362 c.472_474delGCCinsAG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620391 c.501G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620409 c.519C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620544 c.654G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620553 c.663T>C synonymous_variant 0.95 capreomycin Not assoc w R
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620559 c.669A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620569 c.679_681delGGAinsCG frameshift_variant&missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620583 c.693G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>T synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620604 c.714C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620646 c.756G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620647 c.757_759delGAAinsCG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620745 c.855G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620757 c.867C>T synonymous_variant 0.99 capreomycin
amikacin
kanamycin
ccsA 620763 c.873G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620766 c.876C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620790 c.900C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620832 c.942C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656502 c.969C>T synonymous_variant 1.0 ethionamide
Rv0565c 656511 c.960T>C synonymous_variant 0.95 ethionamide Not assoc w R - Interim
Rv0565c 656526 c.945G>A synonymous_variant 1.0 ethionamide
Rv0565c 656535 c.936C>G synonymous_variant 1.0 ethionamide
Rv0565c 656540 p.Ser311Gly missense_variant 1.0 ethionamide
Rv0565c 656543 p.Thr310Ala missense_variant 1.0 ethionamide
Rv0565c 656544 c.925_927delATCinsGG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 656551 p.Asn307Ser missense_variant 1.0 ethionamide
Rv0565c 656559 c.912C>T synonymous_variant 1.0 ethionamide
Rv0565c 656565 c.906C>T synonymous_variant 1.0 ethionamide
Rv0565c 656568 c.903G>C synonymous_variant 1.0 ethionamide
Rv0565c 656583 c.888A>C synonymous_variant 1.0 ethionamide
Rv0565c 656604 p.Arg289Asn missense_variant 1.0 ethionamide
Rv0565c 656611 p.Thr287Lys missense_variant 1.0 ethionamide
Rv0565c 656622 p.Glu283Asp missense_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 1.0 ethionamide
Rv0565c 657312 c.159C>T synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657336 c.135G>A synonymous_variant 1.0 ethionamide
Rv0565c 657340 p.Ala44Glu missense_variant 1.0 ethionamide
Rv0565c 657345 c.124_126delAGGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657369 c.100_102delCAGinsGA frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657372 c.99G>C synonymous_variant 0.97 ethionamide
Rv0565c 657380 p.Arg31Ser missense_variant 1.0 ethionamide
Rv0565c 657381 c.90A>G synonymous_variant 1.0 ethionamide
Rv0565c 657386 p.Ile29Leu missense_variant 1.0 ethionamide
Rv0565c 657387 c.82_84delATCinsCG frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657402 c.69C>A synonymous_variant 1.0 ethionamide
Rv0565c 657405 c.66G>C synonymous_variant 1.0 ethionamide
Rv0565c 657408 c.63A>C synonymous_variant 1.0 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657613 c.-143G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657617 c.-147G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657647 c.-179_-177delGTCinsAT upstream_gene_variant 1.0 ethionamide
Rv0565c 657653 c.-183C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657700 c.-230A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657724 c.-254A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657725 c.-255G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657728 c.-260_-258delAGCinsGT upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731687 c.-243G>A upstream_gene_variant 0.99 isoniazid
hadA 731689 c.-241A>G upstream_gene_variant 1.0 isoniazid
hadA 731693 c.-237C>T upstream_gene_variant 1.0 isoniazid
hadA 731694 c.-235_-234delCG upstream_gene_variant 1.0 isoniazid
hadA 731698 c.-232_-231insTGACAGAGATTTG upstream_gene_variant 1.0 isoniazid
hadA 731707 c.-223C>A upstream_gene_variant 1.0 isoniazid
hadA 731709 c.-221_-220delGAinsCGC upstream_gene_variant 1.0 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 1.0 isoniazid
hadA 731720 c.-210C>A upstream_gene_variant 1.0 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 1.0 isoniazid
hadA 731732 c.-198G>C upstream_gene_variant 1.0 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.98 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731798 c.-132C>T upstream_gene_variant 1.0 isoniazid
hadA 731801 c.-129C>T upstream_gene_variant 1.0 isoniazid
hadA 731822 c.-108G>A upstream_gene_variant 1.0 isoniazid
hadA 732345 p.Tyr139Leu missense_variant 1.0 isoniazid
hadA 732361 c.432C>T synonymous_variant 1.0 isoniazid
hadA 732364 c.435T>G synonymous_variant 1.0 isoniazid
hadA 732366 p.Ala146Val missense_variant 1.0 isoniazid
hadA 732376 c.447T>C synonymous_variant 1.0 isoniazid
hadA 732378 c.449_450insGGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732382 c.453G>A synonymous_variant 0.98 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734072 c.-182C>T upstream_gene_variant 1.0 rifampicin
nusG 734075 c.-179T>A upstream_gene_variant 1.0 rifampicin
nusG 734093 c.-161A>G upstream_gene_variant 1.0 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 1.0 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 1.0 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734132 c.-122G>A upstream_gene_variant 1.0 rifampicin
nusG 734143 c.-111C>T upstream_gene_variant 1.0 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 1.0 rifampicin
nusG 734175 c.-79_-77delGGTinsAC upstream_gene_variant 1.0 rifampicin
nusG 734180 c.-74T>C upstream_gene_variant 1.0 rifampicin
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734190 c.-64C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734194 c.-60C>G upstream_gene_variant 1.0 rifampicin
nusG 734201 c.-53G>C upstream_gene_variant 1.0 rifampicin
nusG 734202 c.-52G>A upstream_gene_variant 1.0 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734224 c.-30G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734225 c.-29_-28insT upstream_gene_variant 1.0 rifampicin
nusG 734229 c.-24delG upstream_gene_variant 1.0 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 1.0 rifampicin
nusG 734250 c.-4A>G upstream_gene_variant 1.0 rifampicin
nusG 734298 c.45T>C synonymous_variant 1.0 rifampicin
nusG 734301 c.48A>G synonymous_variant 1.0 rifampicin
nusG 734302 p.Thr17Gln missense_variant 1.0 rifampicin
nusG 734308 p.Ala19Pro missense_variant 1.0 rifampicin
nusG 734311 c.58_61delAACGinsGGTATC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734318 p.Phe22Cys missense_variant 1.0 rifampicin
nusG 734319 c.67_68delCA frameshift_variant 1.0 rifampicin
nusG 734325 c.72T>C synonymous_variant 1.0 rifampicin
nusG 734327 p.Ala25Val missense_variant 1.0 rifampicin
nusG 734330 p.Ala26Glu missense_variant 1.0 rifampicin Uncertain significance
nusG 734333 p.Ala27Val missense_variant 0.99 rifampicin
nusG 734352 c.99T>C synonymous_variant 1.0 rifampicin
nusG 734360 p.Ala36Val missense_variant 1.0 rifampicin Uncertain significance
nusG 734385 c.132C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734397 p.Asp48Glu missense_variant 1.0 rifampicin
nusG 734409 c.156T>G synonymous_variant 1.0 rifampicin
nusG 734421 c.168A>G synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734502 c.249G>A synonymous_variant 1.0 rifampicin
nusG 734520 c.267C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734604 c.351C>T synonymous_variant 1.0 rifampicin
nusG 734607 c.354C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734622 c.369G>A synonymous_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 1.0 rifampicin
nusG 734634 c.381G>C synonymous_variant 1.0 rifampicin
nusG 734637 c.384G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734652 c.399T>C synonymous_variant 1.0 rifampicin
nusG 734655 c.402G>T synonymous_variant 1.0 rifampicin
nusG 734658 c.405A>G synonymous_variant 1.0 rifampicin Not assoc w R
nusG 734661 c.408A>C synonymous_variant 1.0 rifampicin
nusG 734664 c.411T>G synonymous_variant 1.0 rifampicin
nusG 734667 c.414C>T synonymous_variant 1.0 rifampicin
nusG 734673 c.420A>G synonymous_variant 1.0 rifampicin
nusG 734680 p.Ala143Thr missense_variant 1.0 rifampicin
nusG 734685 c.432C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734794 p.Val181Leu missense_variant 1.0 rifampicin
nusG 734811 c.558G>A synonymous_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734841 c.588G>A synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>C synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>G synonymous_variant 1.0 rifampicin
nusG 734865 c.612G>A synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734883 c.630C>G synonymous_variant 1.0 rifampicin
nusG 734886 c.633A>G synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734925 c.672C>G synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734941 c.688C>T synonymous_variant 1.0 rifampicin
nusG 734950 p.Gly233Asn missense_variant 1.0 rifampicin
nusG 734955 c.702A>G synonymous_variant 1.0 rifampicin
nusG 734970 c.717G>A splice_region_variant&stop_retained_variant 1.0 rifampicin
rpoB 759478 c.-329G>T upstream_gene_variant 1.0 rifampicin
rpoB 759486 c.-321C>T upstream_gene_variant 1.0 rifampicin
rpoB 759488 c.-319C>T upstream_gene_variant 1.0 rifampicin
rpoB 759490 c.-317G>C upstream_gene_variant 1.0 rifampicin
rpoB 759491 c.-316C>T upstream_gene_variant 1.0 rifampicin
rpoB 759497 c.-310G>T upstream_gene_variant 1.0 rifampicin
rpoB 759500 c.-307A>G upstream_gene_variant 1.0 rifampicin
rpoB 759502 c.-305A>G upstream_gene_variant 1.0 rifampicin
rpoB 759522 c.-285T>C upstream_gene_variant 1.0 rifampicin
rpoB 759532 c.-275A>G upstream_gene_variant 1.0 rifampicin
rpoB 759533 c.-274T>C upstream_gene_variant 1.0 rifampicin
rpoB 759537 c.-270G>C upstream_gene_variant 1.0 rifampicin
rpoB 759542 c.-265_-262delGGTTinsAGGTA upstream_gene_variant 1.0 rifampicin
rpoB 759550 c.-257C>T upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759552 c.-255_-252delGGGTinsATGGGC upstream_gene_variant 1.0 rifampicin
rpoB 759634 c.-173A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759636 c.-171C>T upstream_gene_variant 1.0 rifampicin
rpoB 759643 c.-164T>C upstream_gene_variant 1.0 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759654 c.-152_-151delCA upstream_gene_variant 1.0 rifampicin
rpoB 759658 c.-149T>C upstream_gene_variant 1.0 rifampicin
rpoB 759671 c.-136G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759675 c.-132T>C upstream_gene_variant 1.0 rifampicin
rpoB 759676 c.-131A>G upstream_gene_variant 1.0 rifampicin
rpoB 759697 c.-110A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoB 759698 c.-109C>T upstream_gene_variant 1.0 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 1.0 rifampicin
rpoB 759715 c.-92G>A upstream_gene_variant 1.0 rifampicin
rpoB 759725 c.-82A>C upstream_gene_variant 1.0 rifampicin
rpoB 759732 c.-75_-74insT upstream_gene_variant 1.0 rifampicin
rpoB 759742 c.-65G>A upstream_gene_variant 0.98 rifampicin
rpoB 759950 c.144T>G synonymous_variant 1.0 rifampicin
rpoB 759956 c.150C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 759986 c.180T>C synonymous_variant 1.0 rifampicin
rpoB 759991 p.Pro62Gln missense_variant 1.0 rifampicin
rpoB 760007 c.201C>G synonymous_variant 1.0 rifampicin
rpoB 760010 c.204C>T synonymous_variant 1.0 rifampicin
rpoB 760014 p.Glu70Gln missense_variant 1.0 rifampicin
rpoB 760019 c.213G>C synonymous_variant 1.0 rifampicin
rpoB 760025 c.219T>C synonymous_variant 1.0 rifampicin
rpoB 760027 p.Val74Ala missense_variant 1.0 rifampicin
rpoB 760030 p.Asn75Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 760034 c.228A>G synonymous_variant 1.0 rifampicin
rpoB 760037 c.231G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760043 c.237C>G synonymous_variant 1.0 rifampicin
rpoB 760046 c.240G>T synonymous_variant 1.0 rifampicin
rpoB 760067 c.261G>C synonymous_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>A synonymous_variant 1.0 rifampicin
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760148 c.342C>T synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760325 c.519G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.99 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760343 c.537G>C synonymous_variant 0.99 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760412 c.606C>T synonymous_variant 1.0 rifampicin
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>T synonymous_variant 1.0 rifampicin
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760427 c.621G>A synonymous_variant 1.0 rifampicin
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 1.0 rifampicin
rpoB 760463 c.657C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760490 c.684C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 760508 c.702G>C synonymous_variant 1.0 rifampicin
rpoB 760514 c.708C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760518 p.Thr238Ser missense_variant 1.0 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243His missense_variant 1.0 rifampicin
rpoB 760547 c.741G>T synonymous_variant 1.0 rifampicin
rpoB 760561 c.757_758delCG frameshift_variant 1.0 rifampicin
rpoB 760567 c.761delCinsGGG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760601 c.795C>T synonymous_variant 0.99 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760727 c.921C>G synonymous_variant 1.0 rifampicin
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760775 c.969G>C synonymous_variant 1.0 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760848 p.Thr348Ala missense_variant 1.0 rifampicin
rpoB 760858 p.Val351Ala missense_variant 1.0 rifampicin Uncertain significance
rpoB 760868 c.1062C>T synonymous_variant 1.0 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760920 c.1114C>T synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760934 c.1128C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.99 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761126 c.1320G>C synonymous_variant 1.0 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>T synonymous_variant 1.0 rifampicin
rpoB 761201 c.1395G>A synonymous_variant 1.0 rifampicin
rpoB 761204 c.1398C>T synonymous_variant 1.0 rifampicin
rpoB 761207 c.1401C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 1.0 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761285 c.1479G>A synonymous_variant 1.0 rifampicin
rpoB 761300 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761333 c.1527G>C synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>G synonymous_variant 1.0 rifampicin
rpoB 761357 c.1551G>C synonymous_variant 1.0 rifampicin
rpoB 761361 c.1555_1556delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 761373 p.Val523His missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761439 c.1633_1635delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761477 c.1671C>G synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761510 c.1704T>A synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 1.0 rifampicin
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761657 c.1851C>A synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761717 c.1911C>T synonymous_variant 1.0 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.99 rifampicin
rpoB 761847 p.Cys681Ser missense_variant 1.0 rifampicin
rpoB 761864 c.2058G>T synonymous_variant 1.0 rifampicin
rpoB 761867 c.2061C>T synonymous_variant 1.0 rifampicin
rpoB 761870 p.Asp688Glu missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761897 c.2091C>G synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761913 c.2107_2109delGACinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761936 c.2130C>T synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761972 c.2166C>A synonymous_variant 1.0 rifampicin
rpoB 761990 c.2184G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762029 c.2223C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762050 c.2244G>A synonymous_variant 1.0 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762164 c.2358C>T synonymous_variant 1.0 rifampicin
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762212 c.2406G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762389 c.-981G>A upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762449 c.-921C>T upstream_gene_variant 1.0 rifampicin
rpoC 762452 c.-918G>T upstream_gene_variant 1.0 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762490 p.Val895Ala missense_variant 1.0 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.95 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.95 rifampicin
rpoB 762515 c.2709C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762521 c.-849C>G upstream_gene_variant 1.0 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762575 c.-795C>T upstream_gene_variant 0.99 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.98 rifampicin
rpoC 762596 c.-774G>T upstream_gene_variant 0.98 rifampicin
rpoC 762701 c.-669T>C upstream_gene_variant 1.0 rifampicin
rpoC 762707 c.-663G>C upstream_gene_variant 1.0 rifampicin
rpoC 762710 c.-660G>C upstream_gene_variant 1.0 rifampicin
rpoC 762728 c.-642C>G upstream_gene_variant 1.0 rifampicin
rpoC 762743 c.-627G>C upstream_gene_variant 1.0 rifampicin
rpoB 762746 c.2940G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762759 p.Cys985Ala missense_variant 1.0 rifampicin
rpoC 762776 c.-594C>T upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762791 c.-579G>C upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762814 p.Met1003Lys missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762824 c.-546C>T upstream_gene_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762957 c.3151C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763064 c.-306G>A upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763082 c.-288C>A upstream_gene_variant 1.0 rifampicin
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoB 763175 c.3369G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoC 763211 c.-159C>T upstream_gene_variant 1.0 rifampicin
rpoC 763217 c.-153G>A upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoC 763247 c.-123G>A upstream_gene_variant 1.0 rifampicin
rpoC 763253 c.-117G>C upstream_gene_variant 1.0 rifampicin
rpoC 763256 c.-114G>A upstream_gene_variant 1.0 rifampicin
rpoC 763274 c.-96G>C upstream_gene_variant 0.99 rifampicin
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763289 c.3483C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763301 c.-69C>T upstream_gene_variant 0.94 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>G synonymous_variant 1.0 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763435 c.66A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763480 c.111C>G synonymous_variant 1.0 rifampicin
rpoC 763483 c.114G>C synonymous_variant 1.0 rifampicin
rpoC 763484 c.115_117delCTTinsTG frameshift_variant&missense_variant 0.99 rifampicin
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>T synonymous_variant 1.0 rifampicin
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763621 c.252C>G synonymous_variant 1.0 rifampicin
rpoC 763658 c.289_291delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763721 c.352C>T synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>A synonymous_variant 1.0 rifampicin
rpoC 763790 c.421_423delGAGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763795 c.426G>A synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763835 p.Ala156Met missense_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763870 c.501C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763882 c.513G>A synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>T synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763921 c.552G>C synonymous_variant 1.0 rifampicin
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.99 rifampicin
rpoC 763948 c.579G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763963 c.594C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763967 p.Gly200Ser missense_variant 1.0 rifampicin
rpoC 763972 c.603C>T synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764002 c.633C>G synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764080 c.711C>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764095 c.726C>G synonymous_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 1.0 rifampicin
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764212 c.843C>T synonymous_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764218 c.849C>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764269 c.900G>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764314 c.945C>T synonymous_variant 1.0 rifampicin
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764329 c.960C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764428 c.1059G>T synonymous_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764455 c.1086G>A synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 1.0 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>C synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764635 c.1266C>T synonymous_variant 1.0 rifampicin
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764656 c.1287C>G synonymous_variant 1.0 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764692 c.1323C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764696 c.1327C>T synonymous_variant 1.0 rifampicin
rpoC 764719 c.1350G>A synonymous_variant 1.0 rifampicin
rpoC 764746 c.1377G>A synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764785 c.1416C>A synonymous_variant 1.0 rifampicin
rpoC 764791 c.1422C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.99 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 1.0 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764833 c.1464A>G synonymous_variant 1.0 rifampicin
rpoC 764836 c.1467G>A synonymous_variant 0.99 rifampicin
rpoC 764842 c.1473C>T synonymous_variant 1.0 rifampicin
rpoC 764845 c.1476C>A synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764863 c.1494G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 1.0 rifampicin
rpoC 764908 c.1539G>A synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765022 c.1653G>T synonymous_variant 1.0 rifampicin
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1686delTCCinsAGT synonymous_variant 1.0 rifampicin
rpoC 765076 c.1707A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765085 c.1716T>C synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765122 c.1753C>T synonymous_variant 0.99 rifampicin
rpoC 765130 c.1761C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765259 c.1890G>C synonymous_variant 1.0 rifampicin
rpoC 765283 c.1914C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765286 c.1917G>A synonymous_variant 1.0 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.99 rifampicin
rpoC 765295 c.1926G>C synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765312 p.Ala648Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 765315 p.Glu649Ala missense_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765357 p.Met663Thr missense_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765371 c.2002C>T synonymous_variant 1.0 rifampicin
rpoC 765376 c.2007C>T synonymous_variant 1.0 rifampicin
rpoC 765379 c.2010G>T synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765413 c.2044_2046delCCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765524 p.Ala719Ser missense_variant 1.0 rifampicin
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765550 c.2181C>T synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765611 p.His748Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 1.0 rifampicin
rpoC 765640 c.2271A>G synonymous_variant 1.0 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765662 c.2293T>C synonymous_variant 1.0 rifampicin
rpoC 765670 c.2301C>T synonymous_variant 1.0 rifampicin
rpoC 765688 c.2319G>A synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765727 c.2358T>C synonymous_variant 1.0 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 1.0 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765850 c.2481G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765868 c.2499G>A synonymous_variant 1.0 rifampicin
rpoC 765871 c.2502T>C synonymous_variant 1.0 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765908 c.2539C>T synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765962 c.2593T>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766061 c.2692_2694delGTCinsAG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766120 c.2751A>G synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.99 rifampicin Uncertain significance
rpoC 766162 c.2793C>T synonymous_variant 1.0 rifampicin
rpoC 766174 c.2805C>T synonymous_variant 1.0 rifampicin
rpoC 766231 c.2862T>G synonymous_variant 1.0 rifampicin
rpoC 766234 c.2865T>G synonymous_variant 1.0 rifampicin
rpoC 766240 c.2871T>C synonymous_variant 1.0 rifampicin
rpoC 766255 c.2886G>T synonymous_variant 1.0 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 1.0 rifampicin
rpoC 766265 c.2896C>T synonymous_variant 1.0 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 1.0 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 1.0 rifampicin
rpoC 766279 c.2910C>G synonymous_variant 0.97 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.99 rifampicin
rpoC 766288 c.2919C>T synonymous_variant 1.0 rifampicin
rpoC 766309 c.2940G>A synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766351 c.2982C>A synonymous_variant 1.0 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766372 c.3003G>A synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766429 c.3060C>G synonymous_variant 1.0 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766459 c.3090G>T synonymous_variant 1.0 rifampicin
rpoC 766462 c.3093G>C synonymous_variant 1.0 rifampicin
rpoC 766471 c.3102G>C synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766504 c.3135G>T synonymous_variant 1.0 rifampicin
rpoC 766513 c.3144C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766522 c.3153C>T synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766570 c.3201T>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766607 c.3238_3240delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766654 c.3285C>G synonymous_variant 1.0 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766714 c.3345G>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766753 c.3384C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766883 p.Ser1172Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766957 c.3588G>A synonymous_variant 1.0 rifampicin
rpoC 766958 p.Gly1197Ser missense_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>T synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767149 c.3780C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767239 c.3870T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
rpoC 767288 c.3919C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767317 c.3948C>G synonymous_variant 0.98 rifampicin
mmpL5 775612 p.Ser957Pro missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775621 p.Ser954Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775638 p.Ile948Ala missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775640 c.2841C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775643 c.2838A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775649 c.2832G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775679 c.2802A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775682 c.2799C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775685 c.2796C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775694 c.2787C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775709 c.2772C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775715 c.2764_2766delCGGinsAA frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775736 c.2745C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775748 c.2733T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775754 c.2727C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775763 c.2718T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775766 c.2715G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline
mmpL5 775769 c.2712C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775784 c.2697G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775787 c.2694C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775793 c.2688C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775817 c.2664T>C synonymous_variant 0.99 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775832 c.2649C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775985 c.2496C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2481G>C synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 776054 c.2427G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776075 c.2406C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776084 c.2397C>T synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776132 c.2349A>G synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 776141 c.2340A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776159 p.Tyr774Phe missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776165 c.2316C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776179 c.2302T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776198 c.2283C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776207 c.2274G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776218 p.Ala755Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776230 c.2251T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776234 c.2247A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776274 p.Ala736Asp missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776280 p.Arg734His missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776282 p.Ala733Asn missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776312 c.2169A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776315 c.2166C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776336 c.2145G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 776351 c.2130G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776354 c.2127C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776369 c.2112C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776372 c.2109C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776377 p.Gln702Lys missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776387 c.2094T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776392 p.Asp697Asn missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776414 c.2067C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776417 c.2064G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776435 c.2044_2046delGCTinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776438 c.2043T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776441 c.2040T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776447 c.2034A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776459 c.2020_2022delGCGinsTC frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776503 p.Glu660Gln missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776513 c.1968T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776531 c.1950G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776543 c.1938G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776576 c.1905C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776581 p.Leu634Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776606 c.1873_1875delCAGinsGA frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776612 c.1869C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776624 c.1857C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776645 c.1834_1836delGTCinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776653 p.Ile610Val missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776654 c.1827A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776657 c.1824C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776675 c.1806G>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776693 c.1788C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776706 p.Tyr592Phe missense_variant 0.99 clofazimine
bedaquiline
mmpL5 776717 c.1764A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776741 c.1740C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776762 c.1719T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776768 c.1713T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776771 c.1710T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776777 c.1704C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776792 c.1689T>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 776808 p.Thr558Lys missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776816 c.1665T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776825 c.1654_1656delGAAinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776858 p.Ser541Asp missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776890 p.Ser531Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776911 p.Glu524Gln missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776918 p.Arg521Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776923 p.Ala520Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 776924 c.1557G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776933 c.1548G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776942 c.1539A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776954 c.1527A>G synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 776957 c.1524G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776960 c.1521C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776983 c.1498C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776984 c.1497C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776993 c.1488A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777011 c.1470A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777026 c.1455C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777038 c.1443G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777041 c.1440G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777056 c.1425G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777060 p.Ala474Gly missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777065 c.1416T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777094 c.1387T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777095 c.1386T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777101 c.1378_1380delGCCinsTT frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777119 c.1362C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777140 c.1341G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777143 c.1338G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777176 c.1305G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777187 p.Ala432Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777203 c.1278G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777218 c.1263G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777246 p.Arg412Lys missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777251 c.1230C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777254 c.1227G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777269 c.1212T>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777275 c.1206C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777293 c.1188T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777298 p.Val395Ile missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777320 c.1161C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777337 p.Val382Ile missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777353 c.1128G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777359 c.1122G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777365 c.1116G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777394 c.1087C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777399 p.Thr361Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777401 c.1080G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777410 c.1069_1071delATAinsCG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 777419 c.1062C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777428 c.1053C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777431 c.1050A>G synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 777436 p.Ala349Thr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777449 c.1032C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777455 c.1026G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777467 c.1014G>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777470 c.1011G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777485 c.996T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777494 c.987G>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777511 c.970C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777512 c.969T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777518 c.963G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777527 c.954G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777533 c.948C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777542 c.939G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777563 c.918C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777587 c.894G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777593 c.888G>A synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 777596 c.885G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777605 c.876C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777617 c.864A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777626 c.855C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777629 c.852C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777676 c.805C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777726 p.Phe252Tyr missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777731 c.750C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 777737 c.744T>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777749 c.732C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777763 c.718C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777770 c.711G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777779 c.702G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777796 p.Ser229Ala missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777826 c.655T>C synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 777842 c.639C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777855 p.Ala209Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777865 p.Val206Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777872 c.609T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777875 c.606T>C synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 777888 p.Gln198Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777926 c.555C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777938 c.543T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777949 p.Pro178Ala missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777951 p.Ala177Gln missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777953 c.528T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777958 p.Arg175Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777959 p.Glu174Asp missense_variant 1.0 clofazimine
bedaquiline
mmpL5 777968 c.513C>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777974 c.507C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777986 c.495C>G synonymous_variant 0.99 clofazimine
bedaquiline
mmpL5 778001 c.480A>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpR5 778004 c.-986C>T upstream_gene_variant 0.97 clofazimine
bedaquiline
mmpR5 778013 c.-977A>G upstream_gene_variant 0.97 clofazimine
bedaquiline
mmpR5 778019 c.-971C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778025 c.-965T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778034 c.-956A>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778037 c.-953G>A upstream_gene_variant 0.96 clofazimine
bedaquiline
mmpL5 778057 p.Ser142Gly missense_variant 0.96 clofazimine
bedaquiline
mmpR5 778064 c.-926G>T upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778067 c.-923G>A upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778070 c.-920G>T upstream_gene_variant 0.97 clofazimine
bedaquiline
mmpR5 778073 c.-917G>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778082 c.-908T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778088 c.-902C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778094 c.-896A>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778105 p.Leu126Val missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778106 c.375C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 778118 p.Thr121Lys missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778185 p.Arg99Glu missense_variant 1.0 clofazimine
bedaquiline
mmpR5 778193 c.-797C>T upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778198 c.-792G>A upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778226 c.-764T>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778232 p.Glu83Arg missense_variant 1.0 clofazimine
bedaquiline
mmpR5 778241 c.-749C>T upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778274 c.-716T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778277 c.-713C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778304 p.Ile59Met missense_variant 1.0 clofazimine
bedaquiline
mmpR5 778310 c.-680T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778316 p.Thr55Val missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778334 c.144_146delCAC disruptive_inframe_deletion 1.0 clofazimine
bedaquiline
mmpL5 778340 c.140_141insTAG disruptive_inframe_insertion 1.0 clofazimine
bedaquiline
mmpL5 778356 p.Thr42Leu missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778358 c.121_123delGTCinsTG frameshift_variant&synonymous_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 778363 p.Leu40Val missense_variant 1.0 clofazimine
bedaquiline
mmpR5 778367 c.-623C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778378 p.Ile35Leu missense_variant 1.0 clofazimine
bedaquiline
mmpR5 778385 c.-605C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778394 c.-596A>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778403 c.-587T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpR5 778406 c.-584G>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778510 c.-30T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778530 c.-50C>A upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 778543 p.Glu121Val missense_variant 1.0 clofazimine
bedaquiline
mmpS5 778547 p.Gly120Asp missense_variant 1.0 clofazimine
bedaquiline
mmpS5 778556 p.Thr117Ile missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778561 c.-81A>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 778568 p.Thr113Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778573 c.-93C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 778577 p.Thr110Ser missense_variant 1.0 clofazimine
bedaquiline
mmpS5 778582 c.322_324delGACinsAT frameshift_variant&synonymous_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpS5 778591 c.315G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 778594 c.-114C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778609 c.-129G>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778612 c.-132C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778618 c.-138G>A upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 778629 p.Lys93Gln missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778630 c.-150G>A upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 778651 c.253_255delGCCinsTG frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 778654 c.-174A>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778666 c.-186G>C upstream_gene_variant 0.99 clofazimine
bedaquiline
mmpL5 778672 c.-192A>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778678 c.-198C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778684 c.-204C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778687 c.-207C>T upstream_gene_variant 0.99 clofazimine
bedaquiline
mmpS5 778706 p.Val67Ala missense_variant 1.0 clofazimine
bedaquiline
mmpL5 778711 c.-231T>C upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpL5 778723 c.-243C>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 778726 c.178_180delGTTinsAC frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 778729 c.-249A>G upstream_gene_variant 1.0 clofazimine
bedaquiline
mmpS5 778737 p.Glu57Lys missense_variant 1.0 clofazimine
bedaquiline