Run ID: ERR2026695
Sample name:
Date: 2024-04-16T09:33:48.829361
Number of reads: 8335603
Percentage reads mapped: 58.62
Median coverage: 68.0
Strain: La1.7.1;M.canetti;lineage4.2;lineage6.2;lineage6.3
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage6.2 | West-Africa 2 | RD702 | 0.45 |
lineage6.3 | West-Africa 2 | RD702 | 0.32 |
lineage4.2 | Euro-American | None | 0.67 |
lineage4.6.4 | Euro-American | None | 0.59 |
lineage6.1.3 | West-Africa 2 | RD702 | 0.15 |
lineage1.1.1 | Indo-Oceanic | RD239 | 0.12 |
lineage1.1.3.1 | Indo-Oceanic | RD239 | 0.09 |
La1.7.1 | M.bovis | None | 0.23 |
M.canetti | M.canetti | None | 0.33 |
lineage4.6.2.1 | Euro-American | RD726 | 0.1 |
La1 | M.bovis | None | 0.69 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | katG | c.1246_1248delATCinsTG | Assoc w R | High-level resistance |
c.1144_1146delCTCinsAA | Assoc w R | High-level resistance | ||
p.Ala379Val | Uncertain significance | Mutation from literature | ||
ethambutol | embB | p.Tyr384Asn | Mutation from literature | |
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ethA | c.877_879delTTGinsCA | Assoc w R | |
c.814_816delCTAinsTG | Assoc w R | |||
c.796_798delAGCinsGA | Assoc w R | |||
c.751_753delAGCinsGA | Assoc w R | |||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.139_141delCAGinsGA | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.340_342delATCinsGT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.355_357delGAGinsCA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.412_414delCTAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.421_423delCAGinsGA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.648_658delTGCCGCTGACC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.663_664delCGinsAACAACCGCAATA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.904_906delACAinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.973_975delCAGinsGA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiC | c.751_753delTTGinsCT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.820_822delTTAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1144_1146delGCCinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1270_1272delCTGinsTT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1669_1671delATCinsGT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1742delT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1746_1747insC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.2158_2160delGTCinsAT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiB | c.1099_1101delGACinsCA | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.1237_1239delGACinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 490921 | c.139_141delCAGinsGA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 0.98 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491122 | c.340_342delATCinsGT | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491137 | c.355_357delGAGinsCA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491194 | c.412_414delCTAinsTG | frameshift_variant&stop_gained | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491203 | c.421_423delCAGinsGA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491428 | c.648_658delTGCCGCTGACC | frameshift_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491445 | c.663_664delCGinsAACAACCGCAATA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491686 | c.904_906delACAinsGC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491755 | c.973_975delCAGinsGA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
fbiC | 1303681 | c.751_753delTTGinsCT | frameshift_variant&synonymous_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303750 | c.820_822delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304074 | c.1144_1146delGCCinsTG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304200 | c.1270_1272delCTGinsTT | frameshift_variant&synonymous_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304599 | c.1669_1671delATCinsGT | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304671 | c.1742delT | frameshift_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304676 | c.1746_1747insC | frameshift_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1305088 | c.2158_2160delGTCinsAT | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
katG | 2154864 | c.1246_1248delATCinsTG | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
katG | 2154966 | c.1144_1146delCTCinsAA | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
katG | 2154976 | p.Ala379Val | missense_variant | 1.0 | isoniazid | Uncertain significance | Mutation from literature |
fbiB | 3642633 | c.1099_1101delGACinsCA | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiB | 3642771 | c.1237_1239delGACinsCG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
embB | 4247663 | p.Tyr384Asn | missense_variant | 1.0 | ethambutol | Mutation from literature | |
ethA | 4326595 | c.877_879delTTGinsCA | frameshift_variant&missense_variant | 1.0 | ethionamide | Assoc w R | |
ethA | 4326658 | c.814_816delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | ethionamide | Assoc w R | |
ethA | 4326676 | c.796_798delAGCinsGA | frameshift_variant&missense_variant | 1.0 | ethionamide | Assoc w R | |
ethA | 4326721 | c.751_753delAGCinsGA | frameshift_variant&missense_variant | 1.0 | ethionamide | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 504 | c.504T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 510 | c.510T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 519 | c.519C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R |
dnaA | 522 | c.522T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 525 | c.525T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 528 | c.528G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 534 | c.534T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 540 | c.540C>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 552 | c.552G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 558 | c.558G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 564 | c.564C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 568 | c.568_570delGCCinsAT | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 571 | c.571T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 585 | c.585A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 597 | c.597C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 600 | c.600T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 609 | c.609C>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 612 | c.612G>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 633 | c.633T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 636 | c.636C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 642 | c.642G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 645 | c.645A>G | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
dnaA | 654 | c.654A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 660 | c.660G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 663 | c.663A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 666 | c.666C>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 672 | c.672T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 675 | c.675C>A | synonymous_variant | 0.99 | isoniazid | |
dnaA | 678 | c.678A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 681 | c.681G>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 693 | c.693A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 699 | c.699G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 711 | c.711C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 753 | c.753C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 765 | c.765G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 783 | c.783C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 795 | c.795A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 801 | c.801G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 802 | c.802C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 805 | c.805_807delTTGinsCC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 813 | c.813C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 876 | c.876C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 888 | c.888C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 903 | c.903C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 909 | c.909A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 912 | c.912T>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 933 | c.933C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 954 | c.954G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 975 | c.975G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 984 | c.984T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 996 | c.996A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
dnaA | 1020 | c.1020C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1035 | c.1035A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1038 | c.1038A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1050 | c.1050G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1059 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1074 | c.1074C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1080 | c.1080C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1107 | c.1107C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1122 | c.1122C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1128 | c.1128G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1134 | c.1134G>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1146 | c.1146C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1167 | c.1167A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1176 | c.1176A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1179 | c.1179G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1182 | c.1182G>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1200 | c.1200C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1203 | c.1203T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1219 | p.Asn407Gly | missense_variant | 1.0 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1278 | c.1278T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1281 | c.1281C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1293 | c.1293T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1299 | c.1299G>C | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
dnaA | 1302 | c.1302C>T | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.99 | isoniazid | |
dnaA | 1323 | c.1323C>T | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
dnaA | 1329 | c.1329A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1338 | c.1338T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1356 | c.1356T>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1365 | c.1365C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1368 | c.1368T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1374 | c.1374G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1375 | c.1375_1377delTTGinsCA | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 1383 | c.1383A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1395 | c.1395G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1401 | c.1401C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1404 | c.1404T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1449 | c.1449G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1473 | c.1473T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
gyrB | 6086 | p.Thr283Ser | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6091 | c.852G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6097 | c.858G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6103 | c.864G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6123 | p.Ala295Gly | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6172 | c.933C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6178 | c.939C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6181 | c.942C>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6184 | c.945C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6205 | c.966C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6209 | c.970C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6320 | p.Lys361Arg | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6334 | c.-968G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6352 | c.1113C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6391 | c.1152G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6400 | c.-902C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6409 | c.-893A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6415 | c.-887G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6469 | c.-833T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6472 | c.-830G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6484 | c.-818A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6487 | c.-815C>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6491 | p.Ile418Leu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6496 | c.-806G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6499 | c.-803A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6502 | c.-800T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6508 | c.-794A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6535 | c.-767C>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6541 | c.1302C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6542 | p.Ile435Leu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6550 | c.1311A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6551 | c.1312T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6563 | c.1324C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6571 | c.-731T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6577 | c.1338T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6580 | c.-722C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6583 | c.1344G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6589 | c.-713G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6592 | c.-710C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6646 | c.-656C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6724 | c.-578G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6727 | c.-575G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6733 | c.-569G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6739 | c.-563C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6764 | c.-538C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6769 | c.-533C>T | upstream_gene_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6775 | c.-527G>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6778 | c.-524C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6787 | c.-515G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6823 | c.-479G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6824 | c.1585C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6865 | c.-437G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6866 | c.-436C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6877 | c.-425G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6916 | c.-386G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6926 | c.1687T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6950 | c.1711_1713delCTCinsTG | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 6966 | p.Ser576Thr | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrB | 6970 | p.Asp577Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6991 | c.-311C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6994 | c.-308C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7009 | c.-293G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7012 | c.1773G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7018 | c.-284G>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7024 | c.-278G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7027 | c.-275G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7066 | c.-236G>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7072 | c.-230G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7081 | c.-221T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7100 | c.1861T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7120 | c.-182T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7123 | c.-179C>A | upstream_gene_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7136 | c.-166T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7144 | c.-158A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7150 | c.-152G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7153 | c.1914G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 7159 | c.1920C>T | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7162 | c.-140C>G | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7177 | c.-125G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7189 | c.-113C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7201 | c.-101G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7210 | c.-92C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7213 | c.-89G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7496 | c.195C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7508 | c.207C>T | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7538 | c.237G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7580 | c.279C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7587 | c.286C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7652 | c.351C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7661 | c.360C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7673 | c.372G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7700 | c.399G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7721 | c.420G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7725 | c.424C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCT | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7775 | c.474C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7797 | c.496_498delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7821 | c.520C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7835 | c.534A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7881 | c.580C>T | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7889 | c.588G>A | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7898 | p.Asp199Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7911 | p.Ala204Cys | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7919 | c.618G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7922 | c.621T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7942 | p.Glu214Ala | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7946 | c.645C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8144 | c.843C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8174 | c.873C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8186 | c.885G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8204 | c.903C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8231 | c.930C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8235 | c.934_936delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8240 | c.939C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8247 | p.Ile316Val | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8258 | c.957G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8279 | c.978G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8282 | c.981G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8340 | c.1039_1041delGCGinsTC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8351 | c.1050C>T | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8354 | c.1053G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8357 | c.1056G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8372 | c.1071G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8393 | c.1092T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8402 | p.Asp367Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8417 | c.1116C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8421 | c.1120_1122delGTGinsAC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8426 | c.1125G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8447 | c.1146C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8450 | c.1149G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8456 | c.1155C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8513 | c.1212C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8535 | p.Glu412Gln | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8540 | c.1239C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8555 | c.1254G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8557 | p.Ala419Val | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8570 | c.1269G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8645 | c.1344C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8717 | c.1416C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8720 | c.1419G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8723 | c.1422G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8731 | p.Gly477Ala | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8741 | c.1440C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8783 | c.1482G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8813 | p.Asp504Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8816 | c.1515C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8822 | c.1521C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8885 | c.1584C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8945 | c.1644G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8954 | c.1653G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8987 | c.1686C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8993 | c.1692C>T | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9003 | c.1702C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9062 | c.1761C>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9064 | p.Ser588Leu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9077 | c.1776C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9092 | c.1791C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9101 | c.1800A>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9104 | c.1803C>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9128 | c.1827C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9134 | c.1833C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9224 | c.1923C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9236 | c.1935G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9239 | c.1938C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9265 | p.Asp655Gly | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9267 | c.1966_1968delAACinsGA | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9278 | c.1977G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9300 | p.Ala667Ser | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9315 | c.2014C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9329 | c.2028C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9335 | c.2034G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9341 | c.2040C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9419 | c.2118T>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9420 | p.Ile707Ala | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9425 | c.2124C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9446 | c.2145C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9452 | c.2151G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9455 | c.2154T>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9458 | c.2157A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9468 | c.2167C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9479 | c.2178G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9483 | c.2182_2184delTCAinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9488 | c.2187G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9494 | c.2193T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9497 | c.2196G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9503 | c.2202T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9506 | c.2205C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9508 | p.Ala736Gly | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9518 | c.2217A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9521 | c.2220C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9527 | c.2226A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9542 | c.2241T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9545 | c.2244A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9548 | c.2247T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9557 | c.2256G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9558 | p.Val753Ile | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9566 | c.2265C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9582 | c.2281A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9585 | c.2284T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9590 | c.2289T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9593 | c.2292G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9597 | c.2296T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9602 | c.2301T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9608 | c.2307C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9617 | c.2316C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9623 | c.2322G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9626 | c.2325T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9629 | c.2328C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9630 | p.Val777Ile | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9641 | c.2340C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9644 | c.2343T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9650 | c.2349G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9656 | c.2355C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9665 | c.2364A>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9674 | c.2373T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9701 | c.2400T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9716 | c.2415T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9719 | c.2418G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13713 | c.-155T>C | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13717 | c.-159T>C | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13741 | c.-183T>A | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13771 | c.-213T>C | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13780 | c.-222C>G | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13786 | c.-228C>G | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13789 | c.-231A>G | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13792 | c.-234G>T | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13810 | c.-254_-252delACAinsGG | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13816 | c.-258C>T | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13822 | c.-264C>T | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13828 | c.-272_-270delATTinsGC | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13834 | c.-276A>T | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13843 | c.-285T>C | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13852 | c.-294A>G | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13860 | c.-302A>G | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13861 | c.-303C>G | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13864 | c.-306A>C | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13870 | c.-312G>C | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13878 | c.-320C>T | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13893 | c.-335T>G | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13903 | c.-345A>C | upstream_gene_variant | 1.0 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 1.0 | isoniazid | |
fgd1 | 490887 | c.105G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490902 | c.120T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490926 | c.144C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490929 | c.147C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490962 | c.180T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490965 | c.183C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490971 | c.189A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490974 | c.192T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490984 | p.Leu68Met | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490988 | p.Leu69Gln | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490990 | c.208C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490995 | c.213C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491052 | c.270C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491064 | c.282A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491067 | c.285C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491070 | c.288G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491082 | c.300T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491097 | c.315G>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491100 | c.318C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491133 | c.351A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Val | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491151 | c.369G>C | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491154 | c.372G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491166 | c.384G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491178 | c.396G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491262 | c.480C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491280 | c.498C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491289 | c.507C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491310 | c.528C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491316 | c.534C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491334 | c.552C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491337 | c.555C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491343 | c.561C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491355 | c.573C>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491358 | c.576C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491393 | p.Thr204Ser | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491409 | c.627G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491415 | c.633A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491418 | c.636A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491453 | p.Gly224Asp | missense_variant | 1.0 | clofazimine | Uncertain significance |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
fgd1 | 491496 | c.714C>T | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491499 | c.717G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491502 | c.720G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491508 | c.726A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491520 | c.738C>T | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491546 | p.Thr255Ser | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491561 | p.His260Arg | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491570 | p.Asp263Gly | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491590 | p.Lys270Ala | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | p.Asp273Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491622 | c.840C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491667 | c.885A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491673 | c.891A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491694 | c.912C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491703 | c.921C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491709 | c.927A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491712 | p.Phe310Leu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491718 | c.936A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491721 | c.939A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491724 | c.942A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491727 | c.945T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491735 | p.Arg318Leu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491748 | c.966G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491751 | c.969C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491758 | p.Ser326Lys | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491769 | c.987A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491775 | c.993G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575521 | c.174A>G | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575545 | c.198C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575561 | p.Met72Val | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575578 | c.231G>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575581 | c.234C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575588 | p.Arg81Lys | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575596 | c.249C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575605 | c.258G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575611 | c.264C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575629 | c.282A>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575635 | c.288A>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575638 | c.291T>C | synonymous_variant | 0.99 | ethionamide | |
isoniazid | ||||||
mshA | 575641 | c.294A>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575665 | c.318G>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575680 | c.333C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575692 | c.345G>A | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575732 | c.385_387delCTTinsTG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 575746 | c.399C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575764 | c.417C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575770 | c.423G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575772 | p.Val142Ala | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575785 | c.438T>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575786 | p.Tyr147His | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575812 | c.465C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575845 | c.498C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575860 | c.513G>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575863 | c.516G>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575872 | c.525C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575878 | c.531A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575881 | c.534C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575890 | c.543C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.97 | ethionamide | |
isoniazid | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575915 | p.Asp190Asn | missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 575920 | c.573C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575923 | c.576C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575925 | p.Gly193Ala | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575929 | c.582C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575947 | c.600G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575950 | c.603C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575953 | c.606G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575965 | c.618C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575977 | c.630G>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575984 | c.637_639delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 576007 | c.660A>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576012 | p.Arg222Lys | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576017 | p.Val224Leu | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576022 | c.675T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576026 | p.Leu227Ile | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576031 | c.684T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576032 | p.Gly229Arg | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576037 | c.690C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576046 | c.699A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576049 | c.702A>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576058 | c.711G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576061 | c.714C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576076 | c.729T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
ccsA | 619501 | c.-390C>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619510 | c.-381G>A | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619513 | c.-378G>A | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619527 | c.-364C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620106 | p.Phe72Leu | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620112 | c.222A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620126 | p.Gly79Ala | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620130 | c.240G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620139 | c.249C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620141 | p.Ala84Val | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620145 | c.255T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620160 | c.270A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620161 | c.271C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620169 | c.279G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620173 | p.Val95Ile | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620179 | c.289C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620197 | p.Gln103Met | missense_variant | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620208 | c.318G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620236 | c.346C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620245 | p.Leu119Met | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620253 | c.363G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620256 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620275 | c.385C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620296 | c.406_408delCCGinsTA | frameshift_variant&stop_gained | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620328 | c.438G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620361 | c.471C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | c.472_474delGCCinsAG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620391 | c.501G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620409 | c.519C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620433 | c.543C>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620445 | c.555A>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620544 | c.654G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620553 | c.663T>C | synonymous_variant | 0.95 | capreomycin | Not assoc w R |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620559 | c.669A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620569 | c.679_681delGGAinsCG | frameshift_variant&missense_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620583 | c.693G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620598 | c.708C>T | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620604 | c.714C>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620607 | c.717T>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620613 | c.723C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620647 | c.757_759delGAAinsCG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620703 | c.813G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620745 | c.855G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620757 | c.867C>T | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620763 | c.873G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620766 | c.876C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620787 | c.897C>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620790 | c.900C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620793 | c.903G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620796 | c.906C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620808 | c.918T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620832 | c.942C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656487 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656502 | c.969C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656511 | c.960T>C | synonymous_variant | 0.95 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656526 | c.945G>A | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656535 | c.936C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656540 | p.Ser311Gly | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656543 | p.Thr310Ala | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656544 | c.925_927delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 656551 | p.Asn307Ser | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656559 | c.912C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656565 | c.906C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656568 | c.903G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656583 | c.888A>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656604 | p.Arg289Asn | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656611 | p.Thr287Lys | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656622 | p.Glu283Asp | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657303 | c.168C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657306 | c.165C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657312 | c.159C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657336 | c.135G>A | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657340 | p.Ala44Glu | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657345 | c.124_126delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657369 | c.100_102delCAGinsGA | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657372 | c.99G>C | synonymous_variant | 0.97 | ethionamide | |
Rv0565c | 657380 | p.Arg31Ser | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657381 | c.90A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657386 | p.Ile29Leu | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657387 | c.82_84delATCinsCG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657402 | c.69C>A | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657405 | c.66G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657408 | c.63A>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657592 | c.-122A>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657596 | c.-126G>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657613 | c.-143G>A | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657617 | c.-147G>A | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657644 | c.-174G>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657647 | c.-179_-177delGTCinsAT | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657653 | c.-183C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657700 | c.-230A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657724 | c.-254A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657725 | c.-255G>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657728 | c.-260_-258delAGCinsGT | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
hadA | 731687 | c.-243G>A | upstream_gene_variant | 0.99 | isoniazid | |
hadA | 731689 | c.-241A>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731693 | c.-237C>T | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731694 | c.-235_-234delCG | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731698 | c.-232_-231insTGACAGAGATTTG | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731707 | c.-223C>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731709 | c.-221_-220delGAinsCGC | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731711 | c.-219T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731720 | c.-210C>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731729 | c.-201C>T | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731732 | c.-198G>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.98 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731798 | c.-132C>T | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731801 | c.-129C>T | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731822 | c.-108G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 732345 | p.Tyr139Leu | missense_variant | 1.0 | isoniazid | |
hadA | 732361 | c.432C>T | synonymous_variant | 1.0 | isoniazid | |
hadA | 732364 | c.435T>G | synonymous_variant | 1.0 | isoniazid | |
hadA | 732366 | p.Ala146Val | missense_variant | 1.0 | isoniazid | |
hadA | 732376 | c.447T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732378 | c.449_450insGGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
hadA | 732382 | c.453G>A | synonymous_variant | 0.98 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
nusG | 734072 | c.-182C>T | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734075 | c.-179T>A | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734093 | c.-161A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734102 | c.-152G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734132 | c.-122G>A | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734143 | c.-111C>T | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734173 | c.-81C>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734175 | c.-79_-77delGGTinsAC | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734180 | c.-74T>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734183 | c.-71C>T | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734190 | c.-64C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734194 | c.-60C>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734201 | c.-53G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734202 | c.-52G>A | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734205 | c.-49A>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734224 | c.-30G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734225 | c.-29_-28insT | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734229 | c.-24delG | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734236 | c.-18C>T | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734250 | c.-4A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734298 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734301 | c.48A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734302 | p.Thr17Gln | missense_variant | 1.0 | rifampicin | |
nusG | 734308 | p.Ala19Pro | missense_variant | 1.0 | rifampicin | |
nusG | 734311 | c.58_61delAACGinsGGTATC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
nusG | 734318 | p.Phe22Cys | missense_variant | 1.0 | rifampicin | |
nusG | 734319 | c.67_68delCA | frameshift_variant | 1.0 | rifampicin | |
nusG | 734325 | c.72T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734327 | p.Ala25Val | missense_variant | 1.0 | rifampicin | |
nusG | 734330 | p.Ala26Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734333 | p.Ala27Val | missense_variant | 0.99 | rifampicin | |
nusG | 734352 | c.99T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734360 | p.Ala36Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734385 | c.132C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734397 | p.Asp48Glu | missense_variant | 1.0 | rifampicin | |
nusG | 734409 | c.156T>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734424 | c.171G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734460 | c.207G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734502 | c.249G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734520 | c.267C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734604 | c.351C>T | synonymous_variant | 1.0 | rifampicin | |
nusG | 734607 | c.354C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734622 | c.369G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734637 | c.384G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734643 | c.390G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734655 | c.402G>T | synonymous_variant | 1.0 | rifampicin | |
nusG | 734658 | c.405A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
nusG | 734661 | c.408A>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734664 | c.411T>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734667 | c.414C>T | synonymous_variant | 1.0 | rifampicin | |
nusG | 734673 | c.420A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734680 | p.Ala143Thr | missense_variant | 1.0 | rifampicin | |
nusG | 734685 | c.432C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734794 | p.Val181Leu | missense_variant | 1.0 | rifampicin | |
nusG | 734811 | c.558G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734814 | c.561G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734826 | c.573A>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734841 | c.588G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734853 | c.600A>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734862 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734865 | c.612G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734870 | p.Ser206Asn | missense_variant | 1.0 | rifampicin | |
nusG | 734883 | c.630C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734886 | c.633A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734925 | c.672C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734940 | c.687G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734941 | c.688C>T | synonymous_variant | 1.0 | rifampicin | |
nusG | 734950 | p.Gly233Asn | missense_variant | 1.0 | rifampicin | |
nusG | 734955 | c.702A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734970 | c.717G>A | splice_region_variant&stop_retained_variant | 1.0 | rifampicin | |
rpoB | 759478 | c.-329G>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759486 | c.-321C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759488 | c.-319C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759490 | c.-317G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759491 | c.-316C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759497 | c.-310G>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759500 | c.-307A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759502 | c.-305A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759522 | c.-285T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759532 | c.-275A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759533 | c.-274T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759537 | c.-270G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759542 | c.-265_-262delGGTTinsAGGTA | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759550 | c.-257C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 759552 | c.-255_-252delGGGTinsATGGGC | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759634 | c.-173A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 759636 | c.-171C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759643 | c.-164T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759647 | c.-160T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 759654 | c.-152_-151delCA | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759658 | c.-149T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759671 | c.-136G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 759675 | c.-132T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759676 | c.-131A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759697 | c.-110A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 759698 | c.-109C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759701 | c.-106A>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759715 | c.-92G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759725 | c.-82A>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759732 | c.-75_-74insT | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759742 | c.-65G>A | upstream_gene_variant | 0.98 | rifampicin | |
rpoB | 759950 | c.144T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 759956 | c.150C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 759986 | c.180T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 759991 | p.Pro62Gln | missense_variant | 1.0 | rifampicin | |
rpoB | 760007 | c.201C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760010 | c.204C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760014 | p.Glu70Gln | missense_variant | 1.0 | rifampicin | |
rpoB | 760019 | c.213G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760025 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760027 | p.Val74Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760030 | p.Asn75Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760034 | c.228A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760037 | c.231G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760043 | c.237C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760046 | c.240G>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760067 | c.261G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760070 | c.264T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760091 | c.285G>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760118 | c.312T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760148 | c.342C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760325 | c.519G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 760343 | c.537G>C | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760380 | p.Thr192Leu | missense_variant | 1.0 | rifampicin | |
rpoB | 760403 | c.597C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760412 | c.606C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760415 | c.609C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760418 | c.612G>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760427 | c.621G>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760454 | c.648C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760463 | c.657C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760478 | c.672C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760490 | c.684C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 760508 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760514 | c.708C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760518 | p.Thr238Ser | missense_variant | 1.0 | rifampicin | |
rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243His | missense_variant | 1.0 | rifampicin | |
rpoB | 760547 | c.741G>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760561 | c.757_758delCG | frameshift_variant | 1.0 | rifampicin | |
rpoB | 760567 | c.761delCinsGGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760601 | c.795C>T | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760721 | c.915C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760727 | c.921C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760755 | c.949_951delCATinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760764 | p.Glu320Gln | missense_variant | 1.0 | rifampicin | |
rpoB | 760775 | c.969G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760848 | p.Thr348Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760858 | p.Val351Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760868 | c.1062C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760883 | c.1077G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760920 | c.1114C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761084 | c.1278C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.99 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761126 | c.1320G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761168 | c.1362C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761201 | c.1395G>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761204 | c.1398C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761252 | c.1446C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761258 | c.1452G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761282 | c.1476C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761285 | c.1479G>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761300 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761333 | c.1527G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761354 | c.1548C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761357 | c.1551G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761361 | c.1555_1556delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761439 | c.1633_1635delGACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761477 | c.1671C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761510 | c.1704T>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761588 | c.1782C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761600 | c.1794T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761657 | c.1851C>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761666 | c.1860G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761669 | c.1863C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761675 | c.1869G>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761682 | c.1876C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761717 | c.1911C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761819 | c.2013G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.99 | rifampicin | |
rpoB | 761847 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
rpoB | 761864 | c.2058G>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761867 | c.2061C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761870 | p.Asp688Glu | missense_variant | 1.0 | rifampicin | |
rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761897 | c.2091C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761913 | c.2107_2109delGACinsCA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
rpoB | 761921 | c.2115C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761936 | c.2130C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761972 | c.2166C>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761990 | c.2184G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762050 | c.2244G>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762164 | c.2358C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762212 | c.2406G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762314 | c.2508C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 762389 | c.-981G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762449 | c.-921C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762452 | c.-918G>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762488 | c.2682G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762490 | p.Val895Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.95 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.95 | rifampicin | |
rpoB | 762515 | c.2709C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762521 | c.-849C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762527 | c.-843G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762575 | c.-795C>T | upstream_gene_variant | 0.99 | rifampicin | |
rpoC | 762582 | c.-788T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762587 | c.-783G>A | upstream_gene_variant | 0.98 | rifampicin | |
rpoC | 762596 | c.-774G>T | upstream_gene_variant | 0.98 | rifampicin | |
rpoC | 762701 | c.-669T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762707 | c.-663G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762710 | c.-660G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762728 | c.-642C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762743 | c.-627G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762746 | c.2940G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762753 | c.2947T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762759 | p.Cys985Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 762776 | c.-594C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 762791 | c.-579G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762814 | p.Met1003Lys | missense_variant | 1.0 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762824 | c.-546C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762920 | c.3114C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762957 | c.3151C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763007 | c.3201C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763064 | c.-306G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763082 | c.-288C>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763139 | c.-231C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763175 | c.3369G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763211 | c.-159C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763217 | c.-153G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763247 | c.-123G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763274 | c.-96G>C | upstream_gene_variant | 0.99 | rifampicin | |
rpoB | 763283 | c.3477T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763289 | c.3483C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 763301 | c.-69C>T | upstream_gene_variant | 0.94 | rifampicin | |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 763375 | c.6C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763396 | c.27A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763430 | c.61_63delAGGinsCT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763435 | c.66A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763480 | c.111C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763483 | c.114G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763484 | c.115_117delCTTinsTG | frameshift_variant&missense_variant | 0.99 | rifampicin | |
rpoC | 763492 | c.123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763621 | c.252C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763658 | c.289_291delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763699 | c.330G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763709 | c.340C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763721 | c.352C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763768 | c.399C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763790 | c.421_423delGAGinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763795 | c.426G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763870 | c.501C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763882 | c.513G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763888 | c.519G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763921 | c.552G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763936 | c.567C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 763948 | c.579G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763960 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763963 | c.594C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763967 | p.Gly200Ser | missense_variant | 1.0 | rifampicin | |
rpoC | 763972 | c.603C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763987 | c.618C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764080 | c.711C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764095 | c.726C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 764169 | p.Asn267Thr | missense_variant | 1.0 | rifampicin | |
rpoC | 764195 | p.Ser276Ile | missense_variant | 1.0 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764212 | c.843C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764215 | c.846A>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764218 | c.849C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764242 | c.873C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764254 | c.885G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764314 | c.945C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764317 | c.948C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764329 | c.960C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764371 | c.1002G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764428 | c.1059G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764455 | c.1086G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764542 | c.1173C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764548 | c.1179G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764611 | c.1242G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764635 | c.1266C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764656 | c.1287C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764668 | c.1299C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764692 | c.1323C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764696 | c.1327C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764719 | c.1350G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764746 | c.1377G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764785 | c.1416C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764833 | c.1464A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764836 | c.1467G>A | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764842 | c.1473C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764845 | c.1476C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764863 | c.1494G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 764887 | c.1518G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519_1521delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764893 | c.1524T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764908 | c.1539G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765022 | c.1653G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1686delTCCinsAGT | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765076 | c.1707A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765085 | c.1716T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765122 | c.1753C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 765130 | c.1761C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765259 | c.1890G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765283 | c.1914C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765286 | c.1917G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765292 | c.1923G>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 765295 | c.1926G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765312 | p.Ala648Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765315 | p.Glu649Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765357 | p.Met663Thr | missense_variant | 1.0 | rifampicin | |
rpoC | 765370 | c.2001G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765371 | c.2002C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765376 | c.2007C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765379 | c.2010G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765413 | c.2044_2046delCCGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765454 | c.2085C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765524 | p.Ala719Ser | missense_variant | 1.0 | rifampicin | |
rpoC | 765529 | c.2160C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765550 | c.2181C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765611 | p.His748Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 765640 | c.2271A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765662 | c.2293T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765670 | c.2301C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765688 | c.2319G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765727 | c.2358T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765850 | c.2481G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765868 | c.2499G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765871 | c.2502T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765908 | c.2539C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765934 | c.2565C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765937 | c.2568T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765961 | c.2592G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765962 | c.2593T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766009 | c.2640G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766061 | c.2692_2694delGTCinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 766120 | c.2751A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766148 | p.Thr927Ala | missense_variant | 0.99 | rifampicin | Uncertain significance |
rpoC | 766162 | c.2793C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766174 | c.2805C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766231 | c.2862T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766234 | c.2865T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766240 | c.2871T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766255 | c.2886G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766258 | c.2889T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766265 | c.2896C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766270 | c.2901G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 1.0 | rifampicin | |
rpoC | 766279 | c.2910C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.99 | rifampicin | |
rpoC | 766288 | c.2919C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766309 | c.2940G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766315 | c.2946C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766321 | c.2952C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766351 | c.2982C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766372 | c.3003G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766402 | c.3033C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766429 | c.3060C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766459 | c.3090G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766462 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766471 | c.3102G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766480 | c.3111C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766504 | c.3135G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766513 | c.3144C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766522 | c.3153C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766570 | c.3201T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766579 | c.3210C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766607 | c.3238_3240delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766654 | c.3285C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766666 | c.3297C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766714 | c.3345G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766738 | c.3369G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766753 | c.3384C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766769 | c.3400C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766957 | c.3588G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766958 | p.Gly1197Ser | missense_variant | 1.0 | rifampicin | |
rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766978 | c.3609C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767008 | c.3639G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767149 | c.3780C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767197 | c.3828G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767239 | c.3870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767288 | c.3919C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767317 | c.3948C>G | synonymous_variant | 0.98 | rifampicin | |
mmpL5 | 775612 | p.Ser957Pro | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775621 | p.Ser954Thr | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775638 | p.Ile948Ala | missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775640 | c.2841C>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775643 | c.2838A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775649 | c.2832G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775679 | c.2802A>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775682 | c.2799C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775685 | c.2796C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775694 | c.2787C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775709 | c.2772C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775715 | c.2764_2766delCGGinsAA | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775736 | c.2745C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775748 | c.2733T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775754 | c.2727C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775763 | c.2718T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775766 | c.2715G>A | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | ||||||
mmpL5 | 775769 | c.2712C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775784 | c.2697G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775787 | c.2694C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775793 | c.2688C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775817 | c.2664T>C | synonymous_variant | 0.99 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775832 | c.2649C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775856 | c.2625T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775985 | c.2496C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775991 | c.2490G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775997 | c.2484T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776000 | c.2481G>C | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776054 | c.2427G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776060 | c.2421C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776072 | c.2409C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776075 | c.2406C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776084 | c.2397C>T | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776132 | c.2349A>G | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776141 | c.2340A>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776159 | p.Tyr774Phe | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776165 | c.2316C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776179 | c.2302T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776198 | c.2283C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776207 | c.2274G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776218 | p.Ala755Thr | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776230 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776234 | c.2247A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776274 | p.Ala736Asp | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776280 | p.Arg734His | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776282 | p.Ala733Asn | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776312 | c.2169A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776315 | c.2166C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776336 | c.2145G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776351 | c.2130G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776354 | c.2127C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776369 | c.2112C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776372 | c.2109C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776377 | p.Gln702Lys | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776387 | c.2094T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776392 | p.Asp697Asn | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776414 | c.2067C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776417 | c.2064G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776435 | c.2044_2046delGCTinsTG | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776438 | c.2043T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776441 | c.2040T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776447 | c.2034A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776459 | c.2020_2022delGCGinsTC | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776503 | p.Glu660Gln | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776513 | c.1968T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776531 | c.1950G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776543 | c.1938G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776576 | c.1905C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776581 | p.Leu634Met | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776606 | c.1873_1875delCAGinsGA | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776612 | c.1869C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776624 | c.1857C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776645 | c.1834_1836delGTCinsCG | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776653 | p.Ile610Val | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776654 | c.1827A>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776657 | c.1824C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776675 | c.1806G>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776693 | c.1788C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776706 | p.Tyr592Phe | missense_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776717 | c.1764A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776741 | c.1740C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776762 | c.1719T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776768 | c.1713T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776771 | c.1710T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776777 | c.1704C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776792 | c.1689T>C | synonymous_variant | 0.98 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776808 | p.Thr558Lys | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776816 | c.1665T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776825 | c.1654_1656delGAAinsCG | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776858 | p.Ser541Asp | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776890 | p.Ser531Thr | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776911 | p.Glu524Gln | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776918 | p.Arg521Ser | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776923 | p.Ala520Thr | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776924 | c.1557G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776933 | c.1548G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776942 | c.1539A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776954 | c.1527A>G | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776957 | c.1524G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776960 | c.1521C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776983 | c.1498C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776984 | c.1497C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776993 | c.1488A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777011 | c.1470A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777026 | c.1455C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777038 | c.1443G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777041 | c.1440G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777056 | c.1425G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777060 | p.Ala474Gly | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777065 | c.1416T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777094 | c.1387T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777095 | c.1386T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777101 | c.1378_1380delGCCinsTT | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 777119 | c.1362C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777140 | c.1341G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777143 | c.1338G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777176 | c.1305G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777187 | p.Ala432Ser | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777203 | c.1278G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777218 | c.1263G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777246 | p.Arg412Lys | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777251 | c.1230C>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777254 | c.1227G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777269 | c.1212T>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777275 | c.1206C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777293 | c.1188T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777298 | p.Val395Ile | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777320 | c.1161C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777337 | p.Val382Ile | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777353 | c.1128G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777359 | c.1122G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777365 | c.1116G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777394 | c.1087C>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777399 | p.Thr361Met | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777401 | c.1080G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777410 | c.1069_1071delATAinsCG | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 777419 | c.1062C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777428 | c.1053C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777431 | c.1050A>G | synonymous_variant | 0.98 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777436 | p.Ala349Thr | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777449 | c.1032C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777455 | c.1026G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777467 | c.1014G>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777470 | c.1011G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777485 | c.996T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777494 | c.987G>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777511 | c.970C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777512 | c.969T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777518 | c.963G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777527 | c.954G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777533 | c.948C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777542 | c.939G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777563 | c.918C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777587 | c.894G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777593 | c.888G>A | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777596 | c.885G>A | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777605 | c.876C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777617 | c.864A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777626 | c.855C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777629 | c.852C>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777676 | c.805C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777726 | p.Phe252Tyr | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777731 | c.750C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 777737 | c.744T>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777749 | c.732C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777763 | c.718C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777770 | c.711G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777779 | c.702G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777796 | p.Ser229Ala | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777826 | c.655T>C | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777842 | c.639C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777855 | p.Ala209Met | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777865 | p.Val206Leu | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777872 | c.609T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777875 | c.606T>C | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777888 | p.Gln198Leu | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777926 | c.555C>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777938 | c.543T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777949 | p.Pro178Ala | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777951 | p.Ala177Gln | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777953 | c.528T>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777958 | p.Arg175Ser | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777959 | p.Glu174Asp | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777968 | c.513C>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777974 | c.507C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777986 | c.495C>G | synonymous_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778001 | c.480A>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpR5 | 778004 | c.-986C>T | upstream_gene_variant | 0.97 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778013 | c.-977A>G | upstream_gene_variant | 0.97 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778019 | c.-971C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778025 | c.-965T>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778034 | c.-956A>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778037 | c.-953G>A | upstream_gene_variant | 0.96 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778057 | p.Ser142Gly | missense_variant | 0.96 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778064 | c.-926G>T | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778067 | c.-923G>A | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778070 | c.-920G>T | upstream_gene_variant | 0.97 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778073 | c.-917G>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778082 | c.-908T>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778088 | c.-902C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778094 | c.-896A>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778105 | p.Leu126Val | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778106 | c.375C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 778118 | p.Thr121Lys | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778185 | p.Arg99Glu | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778193 | c.-797C>T | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778198 | c.-792G>A | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778226 | c.-764T>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778232 | p.Glu83Arg | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778241 | c.-749C>T | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778274 | c.-716T>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778277 | c.-713C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778304 | p.Ile59Met | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778310 | c.-680T>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778316 | p.Thr55Val | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778334 | c.144_146delCAC | disruptive_inframe_deletion | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778340 | c.140_141insTAG | disruptive_inframe_insertion | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778356 | p.Thr42Leu | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778358 | c.121_123delGTCinsTG | frameshift_variant&synonymous_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 778363 | p.Leu40Val | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778367 | c.-623C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778378 | p.Ile35Leu | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778385 | c.-605C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778394 | c.-596A>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778403 | c.-587T>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpR5 | 778406 | c.-584G>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778510 | c.-30T>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778530 | c.-50C>A | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778543 | p.Glu121Val | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778547 | p.Gly120Asp | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778556 | p.Thr117Ile | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778561 | c.-81A>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778568 | p.Thr113Ser | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778573 | c.-93C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778577 | p.Thr110Ser | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778582 | c.322_324delGACinsAT | frameshift_variant&synonymous_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpS5 | 778591 | c.315G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 778594 | c.-114C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778609 | c.-129G>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778612 | c.-132C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778618 | c.-138G>A | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778629 | p.Lys93Gln | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778630 | c.-150G>A | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778651 | c.253_255delGCCinsTG | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 778654 | c.-174A>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778666 | c.-186G>C | upstream_gene_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778672 | c.-192A>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778678 | c.-198C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778684 | c.-204C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778687 | c.-207C>T | upstream_gene_variant | 0.99 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778706 | p.Val67Ala | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778711 | c.-231T>C | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 778723 | c.-243C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778726 | c.178_180delGTTinsAC | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 778729 | c.-249A>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpS5 | 778737 | p.Glu57Lys | missense_variant | 1.0 | clofazimine | |
bedaquiline |