Run ID: ERR4818929
Sample name:
Date: 2024-03-26T18:34:17.494240
Number of reads: 853291
Percentage reads mapped: 21.46
Median coverage: 8.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.75 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.85 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | p.Ser140Asn | Uncertain significance | Mutation from literature |
| ethambutol | embB | p.His312Arg | Mutation from literature | |
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.412_414delCTAinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.796_798delATCinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiC | c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.751_753delTTGinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.820_822delTTAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.1039_1041delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.1945_1947delATTinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2479_2481delGCCinsTG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.2512_2514delGAAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiA | c.772_774delACGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 491194 | c.412_414delCTAinsTG | frameshift_variant&stop_gained | 0.95 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491578 | c.796_798delATCinsTG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303681 | c.751_753delTTGinsCC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303750 | c.820_822delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303969 | c.1039_1041delGTTinsAC | frameshift_variant&missense_variant | 0.97 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1304875 | c.1945_1947delATTinsGG | frameshift_variant&missense_variant | 0.95 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305409 | c.2479_2481delGCCinsTG | frameshift_variant&missense_variant | 0.95 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1305442 | c.2512_2514delGAAinsCG | frameshift_variant&missense_variant | 0.89 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| katG | 2155693 | p.Ser140Asn | missense_variant | 1.0 | isoniazid | Uncertain significance | Mutation from literature |
| fbiA | 3641314 | c.772_774delACGinsGC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| embB | 4247448 | p.His312Arg | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 690 | c.690G>C | synonymous_variant | 0.69 | isoniazid | |
| dnaA | 693 | c.693A>G | synonymous_variant | 0.83 | isoniazid | Not assoc w R - Interim |
| dnaA | 705 | c.705A>G | synonymous_variant | 0.89 | isoniazid | |
| dnaA | 708 | c.708T>C | synonymous_variant | 0.9 | isoniazid | |
| dnaA | 741 | c.741T>C | synonymous_variant | 0.96 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 768 | c.768C>G | synonymous_variant | 0.93 | isoniazid | |
| dnaA | 771 | c.771A>G | synonymous_variant | 0.93 | isoniazid | |
| dnaA | 777 | c.777A>G | synonymous_variant | 0.94 | isoniazid | |
| dnaA | 783 | c.783C>T | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
| dnaA | 795 | c.795A>C | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
| dnaA | 805 | c.805_807delTTGinsCC | frameshift_variant&missense_variant | 0.91 | isoniazid | Uncertain significance |
| dnaA | 822 | c.822A>G | synonymous_variant | 0.92 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 0.91 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 0.91 | isoniazid | |
| dnaA | 837 | c.837A>G | synonymous_variant | 0.92 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 0.92 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 0.92 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 876 | c.876C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 894 | c.894G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 909 | c.909A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1038 | c.1038A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1047 | c.1047A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1071 | c.1071C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1074 | c.1074C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1077 | c.1077A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1098 | c.1098A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1110 | c.1110T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1125 | c.1125G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1407 | c.1407T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1419 | c.1419C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1428 | c.1428C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1431 | c.1431A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1437 | c.1437G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1441 | c.1441C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1461 | c.1461C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1470 | c.1470C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1473 | c.1473T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1485 | c.1485A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1488 | c.1488A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1497 | c.1497T>G | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6109 | c.870G>C | synonymous_variant | 0.46 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>A | synonymous_variant | 0.41 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6133 | c.894G>C | synonymous_variant | 0.5 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6171 | p.His311Arg | missense_variant | 0.46 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrB | 6184 | c.945C>T | synonymous_variant | 0.54 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6209 | c.970C>T | synonymous_variant | 0.64 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6215 | c.976_978delTCGinsAC | frameshift_variant&missense_variant | 0.62 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6490 | c.-812T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6499 | c.-803A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6508 | c.-794A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6511 | c.-791A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6526 | c.-776T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6535 | c.-767C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6542 | p.Ile435Leu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6550 | c.1311A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6551 | c.1312T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6577 | c.1338T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6580 | c.-722C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6583 | c.-719G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6589 | c.-713G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6616 | c.-686A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6625 | c.-677G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6706 | c.-596G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6724 | c.-578G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6727 | c.-575G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6733 | c.-569G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 0.57 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6748 | c.-554G>A | upstream_gene_variant | 0.43 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6749 | p.Ala504Ser | missense_variant | 0.57 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6763 | c.1524G>C | synonymous_variant | 0.52 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6775 | c.1536G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6787 | c.-515G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Ser | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6866 | c.-436C>T | upstream_gene_variant | 0.54 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6869 | c.-433T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6872 | c.-430T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6877 | c.-425G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6898 | c.-404G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6931 | c.-371A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6955 | c.-347G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6961 | c.-341G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6970 | p.Asp577Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6985 | c.-317C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7012 | c.1773G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7015 | p.Glu592Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7018 | c.-284G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7021 | c.-281G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7027 | c.-275G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7028 | c.1789_1791delGCCinsTG | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7048 | c.-254G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | c.1812A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7100 | c.1861T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7114 | c.-188C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7144 | c.-158A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7153 | c.1914G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7177 | c.-125G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7418 | c.117C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7424 | c.123G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7430 | c.129G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7436 | c.135C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7442 | c.141G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7550 | c.249C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7587 | c.286C>T | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7683 | c.382A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7703 | c.402G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7721 | c.420G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7748 | c.447A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7806 | c.505C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7835 | c.534A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8057 | c.756A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8066 | c.765A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8069 | c.768T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8078 | c.777A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8090 | c.789C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8093 | c.792C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8096 | c.795T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8099 | c.798T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8105 | c.804G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8106 | c.805C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8121 | c.820T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8174 | c.873C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8184 | p.Lys295Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8258 | c.957G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8279 | c.978G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8315 | c.1014G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8360 | c.1059G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8372 | c.1071G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8382 | p.Leu361Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8393 | c.1092T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8401 | p.Asp367Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8408 | c.1107A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8411 | c.1110C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8423 | c.1122G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8447 | c.1146C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8465 | c.1164C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8472 | c.1171C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8492 | c.1191G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8501 | c.1200G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8555 | c.1254G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8556 | p.Ala419Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8571 | c.1270C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8597 | c.1296C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8606 | c.1305C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318_1320delTTGinsCA | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8633 | c.1332C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8637 | c.1336C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8645 | c.1344C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8696 | c.1395G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8731 | p.Gly477Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8738 | c.1437G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8761 | p.Val487Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8792 | c.1491G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8813 | p.Asp504Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528_1530delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8966 | c.1665C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8967 | p.Ala556Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9038 | c.1737C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9044 | c.1743C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9251 | c.1950G>T | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.97 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9268 | p.Asn656Thr | missense_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9276 | c.1975C>T | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9281 | c.1980C>G | synonymous_variant | 0.89 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 0.86 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9341 | c.2040C>G | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9353 | c.2052G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9398 | c.2097T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9407 | c.2106C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9602 | c.2301T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9626 | c.2325T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9630 | p.Val777Ile | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9638 | c.2337C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9644 | c.2343T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9665 | c.2364A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9671 | c.2370G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9674 | c.2373T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9689 | c.2388G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9704 | c.2403T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9708 | c.2407T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 490792 | c.10C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490797 | c.15G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490800 | c.18A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490803 | c.21T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490815 | c.33G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490836 | c.54C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490851 | c.69A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490866 | c.84A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490868 | p.Ala29Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490887 | c.105G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490902 | c.120T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490911 | c.129T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490917 | c.135C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490929 | c.147C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490962 | c.180T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490971 | c.189A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490974 | c.192T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490980 | p.Asn66Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490988 | p.Leu69Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490998 | c.216T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491016 | c.234C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491043 | c.261T>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491049 | c.267T>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491055 | c.273C>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491064 | c.282A>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491091 | c.309T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491097 | c.315G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491110 | p.Ala110Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491115 | c.333G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491144 | p.Ala121Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491166 | c.384G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491168 | p.Phe129Tyr | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491208 | c.426G>C | synonymous_variant | 0.89 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Leu | missense_variant | 0.89 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491560 | p.His260Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491569 | p.Asp263His | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491603 | p.Ala274Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491605 | c.823C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491631 | c.849C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| mshA | 574616 | c.-732G>C | upstream_gene_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 574619 | c.-729C>G | upstream_gene_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 574629 | c.-719_-717delGCCinsTG | upstream_gene_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 574640 | c.-708G>C | upstream_gene_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| mshA | 574650 | c.-698A>C | upstream_gene_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 574671 | c.-677_-675delGCAinsCTG | upstream_gene_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 574676 | c.-672G>C | upstream_gene_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 574683 | c.-665T>C | upstream_gene_variant | 0.94 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574688 | c.-660G>C | upstream_gene_variant | 0.94 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 574712 | c.-636A>G | upstream_gene_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 574718 | c.-630A>G | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 574724 | c.-624T>C | upstream_gene_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| mshA | 574727 | c.-621G>C | upstream_gene_variant | 0.84 | ethionamide | |
| isoniazid | ||||||
| mshA | 574728 | c.-620C>T | upstream_gene_variant | 0.8 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574731 | c.-617A>G | upstream_gene_variant | 0.81 | ethionamide | |
| isoniazid | ||||||
| mshA | 574739 | c.-609T>C | upstream_gene_variant | 0.83 | ethionamide | |
| isoniazid | ||||||
| mshA | 574742 | c.-606G>C | upstream_gene_variant | 0.83 | ethionamide | |
| isoniazid | ||||||
| mshA | 574757 | c.-591G>C | upstream_gene_variant | 0.86 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 574758 | c.-590G>A | upstream_gene_variant | 0.86 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 574763 | c.-585T>C | upstream_gene_variant | 0.86 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574766 | c.-582T>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574782 | c.-566C>G | upstream_gene_variant | 0.81 | ethionamide | |
| isoniazid | ||||||
| mshA | 574790 | c.-558C>G | upstream_gene_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| mshA | 574792 | c.-556T>C | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574799 | c.-549T>G | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574802 | c.-546A>G | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574803 | c.-545A>C | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574811 | c.-537C>G | upstream_gene_variant | 0.73 | ethionamide | |
| isoniazid | ||||||
| mshA | 574832 | c.-516C>G | upstream_gene_variant | 0.8 | ethionamide | |
| isoniazid | ||||||
| mshA | 575587 | c.240C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575590 | c.243T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575605 | c.258G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575618 | c.271C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575623 | c.276C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575629 | c.282A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575632 | c.285G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575635 | c.288A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575638 | c.291T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575641 | c.294A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575649 | p.Val101Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575686 | c.339G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575692 | c.345G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575704 | c.357T>C | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358_360delTTGinsCC | frameshift_variant&missense_variant | 0.91 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575737 | c.390T>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575749 | c.402C>A | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575751 | p.Gly135Ala | missense_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 575788 | c.441C>T | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| mshA | 575806 | c.459G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575833 | c.486C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575905 | c.558G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575920 | c.573C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575924 | p.Gly193Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575929 | c.582C>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| mshA | 575965 | c.618C>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575977 | c.630G>C | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 575980 | c.633T>C | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 576388 | c.1041G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576394 | c.1047G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576421 | c.1074T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576424 | c.1077T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576425 | p.Val360Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576433 | c.1086C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576436 | c.1089A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576448 | c.1101A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576463 | c.1116G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576469 | c.1122G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576472 | c.1125C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576476 | c.1129C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576484 | c.1137C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576487 | c.1140G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619525 | c.-366C>G | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619531 | c.-360T>G | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619535 | c.-356_-354delCAAinsTCG | upstream_gene_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.93 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619558 | c.-333G>C | upstream_gene_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619564 | c.-327C>G | upstream_gene_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619591 | c.-300G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619594 | c.-297G>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619615 | c.-276C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619618 | c.-273C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619627 | c.-264C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619630 | c.-261C>G | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619634 | c.-257_-255delTCCinsGG | upstream_gene_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619646 | c.-245_-243delGTCinsCG | upstream_gene_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619654 | c.-237A>C | upstream_gene_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619655 | c.-236A>G | upstream_gene_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619668 | c.-223_-222delCGinsGC | upstream_gene_variant | 0.82 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619672 | c.-219A>C | upstream_gene_variant | 0.86 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619900 | p.Leu4Val | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619912 | p.Val8Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619932 | c.42C>G | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619962 | c.72G>C | synonymous_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 619969 | p.Val27Ile | missense_variant | 0.9 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R | |||||
| kanamycin | Uncertain significance | |||||
| ccsA | 620169 | c.279G>C | synonymous_variant | 0.91 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620173 | p.Val95Ile | missense_variant | 0.92 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620198 | p.Gln103Leu | missense_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620208 | c.318G>C | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | p.Leu119Met | missense_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620253 | c.363G>C | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620257 | p.Ile123Leu | missense_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620265 | c.375C>G | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620267 | p.Ala126Val | missense_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | p.Ala132Pro | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620295 | c.405G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620307 | c.417C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620319 | c.429C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620349 | c.459A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620362 | p.Ala158Thr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620412 | c.522T>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 0.98 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620427 | c.537C>G | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620433 | c.543C>G | synonymous_variant | 0.98 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620439 | c.549T>C | synonymous_variant | 0.98 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620445 | c.555A>G | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620460 | c.570T>C | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620461 | p.Val191Ile | missense_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620597 | p.Ala236Gly | missense_variant | 0.93 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620607 | c.717T>A | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620631 | c.741T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620647 | c.757_759delGAAinsCG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620685 | c.795G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620703 | c.813G>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620709 | c.819G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620712 | c.822G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620745 | c.855G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620757 | c.867C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620766 | c.876C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620769 | c.879C>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620783 | p.Ala298Val | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620787 | c.897C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620809 | c.919C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620823 | c.933C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620829 | c.939G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620844 | c.954C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| Rv0565c | 657644 | c.-174G>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657653 | c.-183C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657668 | c.-198C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657678 | c.-208A>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657683 | c.-213C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAC | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731753 | c.-177A>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731798 | c.-132C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731843 | c.-87T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731849 | c.-81C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731852 | c.-78A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 732253 | c.324T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732268 | c.339T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732271 | c.342G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732272 | p.Ala115Ser | missense_variant | 1.0 | isoniazid | |
| hadA | 732290 | p.Ile121Val | missense_variant | 0.96 | isoniazid | |
| hadA | 732298 | c.369C>G | synonymous_variant | 0.96 | isoniazid | |
| hadA | 732316 | c.387C>T | synonymous_variant | 0.94 | isoniazid | |
| hadA | 732317 | p.Glu130Gln | missense_variant | 0.94 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 0.94 | isoniazid | |
| hadA | 732328 | p.Asp133Glu | missense_variant | 0.94 | isoniazid | Uncertain significance |
| hadA | 732329 | c.400_402delCTCinsGG | frameshift_variant&missense_variant | 0.94 | isoniazid | Uncertain significance |
| hadA | 732346 | c.417T>C | synonymous_variant | 0.95 | isoniazid | |
| hadA | 732367 | c.438C>G | synonymous_variant | 0.97 | isoniazid | |
| hadA | 732378 | c.449_450insGGA | disruptive_inframe_insertion | 0.94 | isoniazid | |
| hadA | 732382 | c.453G>A | synonymous_variant | 0.94 | isoniazid | |
| hadA | 732389 | c.460_462delTCTinsAGC | synonymous_variant | 1.0 | isoniazid | |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734472 | c.219T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734499 | c.246G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734586 | c.333G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734589 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734610 | c.357C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 759606 | c.-201T>C | upstream_gene_variant | 0.8 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
| rpoB | 760112 | c.306T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760118 | c.312T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760148 | p.Asp114Glu | missense_variant | 0.97 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760271 | c.465C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760283 | c.477G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760343 | c.537G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760415 | c.609C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760460 | c.654G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760511 | c.705G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760520 | c.714C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243His | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | c.757delCinsAT | frameshift_variant&synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760566 | p.Ser254Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760567 | c.762delG | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760634 | c.828T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760751 | c.945G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760754 | c.948G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760755 | c.949_951delCATinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 760763 | c.957C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760764 | p.Glu320Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 760769 | c.963C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760781 | c.975G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760787 | c.981G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760920 | c.1114C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760970 | c.1164G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760973 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761006 | c.1200C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 761124 | c.1318C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761183 | c.1377T>G | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 761192 | c.1386C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761361 | c.1555_1556delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761437 | p.Ala544Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761447 | c.1641C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761452 | p.Val549Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761457 | p.Pro551Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761465 | c.1659G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761504 | c.1698C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761555 | c.1749G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761693 | c.1887G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761711 | c.1905C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761785 | p.Thr660Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761815 | p.Ala670Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761867 | c.2061C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761870 | p.Asp688Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762128 | c.2322G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762138 | c.2332C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762197 | c.2391C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762218 | c.2412T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762296 | c.2490G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762350 | c.2544C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762353 | c.2547C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762407 | c.-963G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762486 | p.Pro894Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.96 | rifampicin | |
| rpoC | 762521 | c.-849C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762795 | p.Asp997Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762836 | c.-534C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762839 | c.-531G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762947 | c.-423C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762977 | c.3171C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763013 | c.3207C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763148 | c.-222G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763202 | c.-168A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763205 | c.-165G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763208 | c.-162T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763214 | c.3408T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763217 | c.-153G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763229 | c.-141G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763235 | c.-135A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763247 | c.-123G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763256 | c.-114G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763375 | c.6C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61_63delAGGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763435 | c.66A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763492 | c.123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763618 | c.249C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763705 | c.336G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763708 | c.339G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763711 | c.342G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763781 | p.Ser138Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763831 | c.462A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 763853 | p.Val162Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763945 | c.576T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763951 | c.582G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763960 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763978 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763991 | c.622_624delATCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 0.95 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764095 | c.726C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764104 | c.735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764182 | p.Asp271Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764209 | c.840C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764215 | c.846A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764218 | c.849C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764254 | c.885G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764338 | c.969G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764344 | c.975C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764371 | c.1002G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764377 | c.1008C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764383 | c.1014C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
| rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 0.96 | rifampicin | |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764611 | c.1242G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764635 | c.1266C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764695 | c.1326T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764713 | c.1344G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764809 | c.1440C>A | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764962 | c.1593G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765011 | c.1642_1643delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765073 | c.1704G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765085 | c.1716T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765103 | c.1734G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765115 | c.1746G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765121 | c.1752G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765129 | p.Tyr587Phe | missense_variant | 1.0 | rifampicin | |
| rpoC | 765133 | c.1764G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765283 | c.1914C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765292 | c.1923G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765298 | c.1929G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765304 | p.Glu645Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 765313 | c.1944C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765317 | c.1948_1950delCTAinsTG | frameshift_variant&stop_gained | 1.0 | rifampicin | |
| rpoC | 765326 | p.His653Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765334 | c.1965C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765346 | c.1977C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765367 | c.1998C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765371 | c.2002C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765397 | c.2028G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765403 | c.2034G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765404 | p.Leu679Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765466 | c.2097C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765493 | c.2124G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765544 | c.2175C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765550 | c.2181C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765559 | c.2190G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765592 | c.2223C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765689 | c.2320C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765727 | c.2358T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 0.98 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765805 | c.2436C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 765871 | c.2502T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765908 | c.2539C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766043 | p.Gln892Glu | missense_variant | 0.93 | rifampicin | |
| rpoC | 766054 | c.2685C>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 766061 | p.Val898Thr | missense_variant | 0.92 | rifampicin | |
| rpoC | 766082 | p.Ala905Gln | missense_variant | 0.9 | rifampicin | |
| rpoC | 766087 | c.2718C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 766093 | c.2724C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 766096 | c.2727G>C | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 766105 | c.2736C>T | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766135 | c.2766G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766327 | c.2958C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766366 | c.2997C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766369 | c.3000C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766462 | c.3093G>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.97 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766530 | p.Arg1054Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766543 | c.3174C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766618 | c.3249G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | p.Glu1092Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766702 | c.3333G>C | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766733 | c.3364_3366delCTGinsTA | frameshift_variant&stop_gained | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766750 | c.3381C>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 766753 | c.3384C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 766754 | p.Glu1129Gln | missense_variant | 0.98 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766777 | c.3408C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766781 | p.Val1138Thr | missense_variant | 0.98 | rifampicin | |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766882 | c.3513C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766978 | c.3609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766981 | c.3612T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767020 | c.3651C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | c.3736_3738delAACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 776678 | c.1803G>C | synonymous_variant | 0.5 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776687 | p.Trp598Phe | missense_variant | 0.71 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776693 | c.1786_1788delGTCinsAG | frameshift_variant&missense_variant | 0.5 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776717 | c.1764A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776741 | c.1740C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781134 | c.-426T>C | upstream_gene_variant | 0.9 | streptomycin | |
| rpsL | 781137 | c.-423G>C | upstream_gene_variant | 0.9 | streptomycin | |
| rpsL | 781138 | c.-422_-421delCAinsGC | upstream_gene_variant | 0.9 | streptomycin | |
| rpsL | 781143 | c.-417T>G | upstream_gene_variant | 0.91 | streptomycin | |
| rpsL | 781155 | c.-405G>C | upstream_gene_variant | 0.94 | streptomycin | |
| rpsL | 781158 | c.-402C>G | upstream_gene_variant | 0.95 | streptomycin | |
| rpsL | 781164 | c.-396T>C | upstream_gene_variant | 0.96 | streptomycin | |
| rpsL | 781173 | c.-387A>C | upstream_gene_variant | 1.0 | streptomycin | |
| rpsL | 781179 | c.-381T>C | upstream_gene_variant | 0.96 | streptomycin | |
| rpsL | 781185 | c.-375T>C | upstream_gene_variant | 0.96 | streptomycin | |
| rpsL | 781189 | c.-371T>C | upstream_gene_variant | 0.96 | streptomycin | |
| rpsL | 781194 | c.-366G>C | upstream_gene_variant | 0.97 | streptomycin | |
| rpsL | 781197 | c.-363A>G | upstream_gene_variant | 0.97 | streptomycin | |
| rpsL | 781224 | c.-336T>C | upstream_gene_variant | 0.96 | streptomycin | |
| rpsL | 781230 | c.-330T>C | upstream_gene_variant | 0.95 | streptomycin | |
| rpsL | 781234 | c.-326G>T | upstream_gene_variant | 0.95 | streptomycin | |
| rpsL | 781240 | c.-320A>T | upstream_gene_variant | 0.95 | streptomycin | |
| rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781763 | c.204C>G | synonymous_variant | 0.98 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 0.98 | streptomycin | Not assoc w R - Interim |
| rpsL | 781808 | c.249C>T | synonymous_variant | 0.94 | streptomycin | |
| rpsL | 781811 | c.252C>T | synonymous_variant | 0.94 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 0.96 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 0.96 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781880 | c.321C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800225 | c.-584T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800498 | c.-311G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800516 | c.-293G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800546 | c.-263T>G | upstream_gene_variant | 0.97 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.94 | linezolid | |
| rplC | 800579 | c.-230C>A | upstream_gene_variant | 0.93 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.93 | linezolid | |
| rplC | 800591 | c.-218C>T | upstream_gene_variant | 0.93 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 0.9 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.87 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.86 | linezolid | |
| rplC | 800672 | c.-137G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800690 | c.-119C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 801159 | c.351C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801171 | c.363A>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 801174 | c.366T>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 801222 | c.414T>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 801246 | c.438C>T | synonymous_variant | 0.98 | linezolid | |
| rplC | 801252 | c.444G>C | synonymous_variant | 0.98 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 0.97 | linezolid | |
| rplC | 801267 | c.459A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801282 | c.474G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801285 | c.477G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801300 | c.492C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 801324 | c.516T>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 801336 | c.528C>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 0.97 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 0.97 | linezolid | |
| rplC | 801349 | p.Leu181Val | missense_variant | 0.97 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 0.97 | linezolid | |
| rplC | 801363 | c.555C>T | synonymous_variant | 0.98 | linezolid | Not assoc w R - Interim |
| rplC | 801367 | p.Ala187Pro | missense_variant | 0.98 | linezolid | |
| rplC | 801387 | c.579G>C | synonymous_variant | 0.95 | linezolid | |
| rplC | 801396 | c.588T>C | synonymous_variant | 0.93 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 0.92 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 0.91 | linezolid | |
| rplC | 801427 | p.Met207Val | missense_variant | 0.91 | linezolid | |
| rplC | 801438 | c.630T>C | synonymous_variant | 0.91 | linezolid | |
| rplC | 801442 | p.Ile212Val | missense_variant | 0.91 | linezolid | |
| fbiC | 1303492 | c.562T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303506 | c.576C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303515 | c.585G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303581 | c.651G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303623 | c.693C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303638 | c.708A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303650 | c.720G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303661 | p.Val244Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303686 | c.756C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303689 | c.759T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303728 | c.798G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303731 | c.801A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303732 | p.Ser268Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303761 | c.831T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303788 | c.858T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303794 | c.864A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303827 | c.897A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303845 | c.915C>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303846 | p.Phe306Val | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303857 | c.927C>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303860 | c.930A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303869 | c.939T>C | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303884 | c.954T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303893 | c.963G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303896 | c.966G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303902 | c.972G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303908 | c.978C>T | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303947 | c.1017T>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303952 | p.Asp341Ala | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303977 | c.1047C>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303980 | c.1050G>A | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303986 | c.1056C>T | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304001 | c.1071C>T | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304019 | c.1089C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304034 | c.1104A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304040 | c.1110C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304049 | c.1119T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304050 | c.1120T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304055 | p.Asp375Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304059 | c.1129C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304079 | c.1149A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304085 | c.1155C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304091 | p.Asp387Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304115 | c.1185A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304121 | c.1191A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304127 | c.1197A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304139 | c.1209G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304142 | c.1212G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304151 | c.1221C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304166 | c.1236A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304169 | c.1239T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304172 | c.1242G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304173 | p.Val415Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304181 | c.1251G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304184 | c.1254G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304199 | c.1269C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304205 | c.1275C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304222 | p.Val431Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304226 | c.1296C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304227 | p.Met433Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304515 | p.Ala529Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304523 | c.1593G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304526 | c.1596T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304541 | c.1611C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304544 | c.1614T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304545 | p.Val539Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304553 | c.1623C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304568 | c.1638T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304754 | c.1824G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304784 | c.1854T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304787 | c.1857T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304832 | c.1902C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304874 | c.1944C>T | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304931 | c.2001C>G | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304958 | c.2028T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304991 | c.2061G>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304994 | c.2064A>C | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304995 | p.Leu689Glu | missense_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305006 | p.Glu692Asp | missense_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 0.84 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305030 | c.2100G>C | synonymous_variant | 0.88 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305033 | c.2103T>C | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305039 | c.2109G>C | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305042 | c.2112A>G | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305045 | c.2115A>G | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305276 | c.2346G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305279 | p.His783Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305320 | p.Gln797Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305336 | c.2406T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305393 | c.2463T>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305399 | c.2469A>G | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305405 | c.2475A>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305422 | p.Ala831Glu | missense_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305430 | p.Val834Thr | missense_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305453 | c.2523C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364751 | c.339C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364760 | c.348C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364784 | c.372C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364811 | c.399A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364814 | c.402C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364818 | c.406_408delCTAinsTG | frameshift_variant&stop_gained | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364835 | c.423C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364856 | c.444C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364865 | c.453G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364868 | c.456T>C | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1460804 | c.-241T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460816 | c.-229T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460831 | c.-214T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460840 | c.-205A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460843 | c.-202G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460852 | c.-193C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460855 | c.-190T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460858 | c.-187C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460882 | c.-163T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460894 | c.-151A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460897 | c.-148A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460900 | c.-145T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460918 | c.-127A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1461089 | c.45G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461097 | p.Ala18Gly | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461101 | c.57T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461107 | c.63C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461113 | c.69C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461131 | c.87T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461150 | p.Ile36Val | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461153 | c.109_111delTCCinsGG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| atpE | 1461158 | c.114T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461159 | p.Val39Ile | missense_variant | 0.97 | bedaquiline | Uncertain significance |
| atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461224 | c.180T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461233 | c.189A>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461254 | c.210T>C | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472030 | n.185G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472044 | n.199G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473290 | n.1445delCinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476746 | n.3089T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| fabG1 | 1674098 | p.Val220Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674114 | c.-88T>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674126 | c.-76G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674129 | c.-73C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674132 | c.-70T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674135 | c.-67C>T | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| fabG1 | 1674136 | p.Ser233Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674141 | c.-61T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674144 | c.-58G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674171 | c.-31T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674270 | c.69T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674471 | c.270G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674486 | c.285T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674489 | c.288G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674537 | c.336C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674540 | c.339C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674555 | c.354G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674561 | c.360C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674570 | c.369G>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674601 | c.400C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674618 | c.417C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674630 | c.429C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674654 | c.453G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674660 | c.459G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674663 | c.462G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674714 | c.513C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517_519delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674726 | c.525G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674729 | c.528G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674747 | c.546C>T | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674750 | c.549T>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 0.93 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674762 | c.561T>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674765 | c.564C>T | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674774 | c.573A>C | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674795 | c.594G>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674813 | c.612C>T | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674837 | c.636C>G | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674840 | c.639C>G | synonymous_variant | 0.94 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674846 | p.Ile215Met | missense_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674855 | c.654C>G | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674873 | c.672G>A | synonymous_variant | 0.96 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 0.95 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674888 | c.687C>T | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833265 | c.-277A>G | upstream_gene_variant | 0.8 | pyrazinamide | |
| rpsA | 1833518 | c.-24_-23delCCinsG | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833604 | c.63C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833613 | c.72C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833622 | c.81C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833634 | c.93G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833748 | c.207C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833754 | c.213G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833771 | p.Asn77Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833806 | c.265C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834120 | c.579G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834192 | c.651C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834255 | c.714C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1834327 | c.786G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834336 | c.795C>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834357 | c.816T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834528 | c.987T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834612 | c.1071G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834699 | p.Glu386Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | c.1224A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834774 | c.1233C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834831 | c.1290G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853450 | c.-156G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853453 | c.-153G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.96 | linezolid | |
| tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853485 | c.-121G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853516 | c.-90C>G | upstream_gene_variant | 1.0 | linezolid | |
| tlyA | 1917960 | c.21T>C | synonymous_variant | 0.87 | capreomycin | |
| tlyA | 1917969 | c.30G>A | synonymous_variant | 0.87 | capreomycin | |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
| tlyA | 1917981 | c.42G>C | synonymous_variant | 0.86 | capreomycin | |
| tlyA | 1917984 | c.45C>G | synonymous_variant | 0.86 | capreomycin | |
| tlyA | 1917990 | c.51G>C | synonymous_variant | 0.86 | capreomycin | |
| tlyA | 1917993 | c.54A>G | synonymous_variant | 0.86 | capreomycin | Not assoc w R - Interim |
| tlyA | 1917996 | c.57A>C | synonymous_variant | 0.86 | capreomycin | |
| tlyA | 1917999 | c.60T>G | synonymous_variant | 0.86 | capreomycin | |
| tlyA | 1918002 | c.63A>G | synonymous_variant | 0.86 | capreomycin | |
| tlyA | 1918022 | p.Gly28Asp | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918417 | c.478T>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918422 | c.483T>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918425 | c.486C>A | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918442 | p.Val168Ala | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918446 | c.507A>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918452 | c.513T>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918453 | p.Ser172Ala | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918457 | p.Arg173Pro | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918464 | c.525C>G | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918476 | c.537A>C | synonymous_variant | 1.0 | capreomycin | |
| tlyA | 1918477 | p.Leu180Met | missense_variant | 1.0 | capreomycin | |
| tlyA | 1918488 | c.549G>A | synonymous_variant | 1.0 | capreomycin | |
| bacA | 2063052 | c.1677T>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063055 | c.1674T>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063058 | c.1671A>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063067 | c.1662T>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063097 | c.1632A>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | Not assoc w R - Interim | |||||
| capreomycin | ||||||
| amikacin | Not assoc w R - Interim | |||||
| bacA | 2063100 | c.1629G>A | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2063106 | c.1623G>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064186 | c.543C>T | synonymous_variant | 0.8 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| ndh | 2101873 | c.1170T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101876 | c.1167C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101888 | c.1153_1155delGTTinsCG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2101891 | c.1152C>G | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101894 | c.1149T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101912 | c.1131G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101915 | c.1128T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101920 | c.1123A>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101924 | c.1119T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101930 | c.1113C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101939 | c.1104A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102836 | c.207T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102842 | c.201A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102845 | c.198A>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102857 | c.186T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102878 | c.165G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102905 | c.138C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102911 | c.132G>C | synonymous_variant | 0.93 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102929 | c.114T>C | synonymous_variant | 0.93 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102934 | p.Asp37Asn | missense_variant | 0.93 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102938 | p.Arg35His | missense_variant | 0.92 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102947 | c.96G>A | synonymous_variant | 0.91 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102953 | c.90A>G | synonymous_variant | 0.9 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| katG | 2155029 | c.1083C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155032 | c.1080T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155050 | p.Thr354Gln | missense_variant | 1.0 | isoniazid | |
| katG | 2155054 | p.Tyr353Phe | missense_variant | 1.0 | isoniazid | |
| katG | 2155056 | c.1056A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155062 | c.1050T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155065 | c.1047C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155068 | c.1044T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155071 | c.1041T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155080 | c.1032G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155698 | c.414C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155736 | p.Met126Leu | missense_variant | 1.0 | isoniazid | |
| katG | 2155740 | p.Gly124Gln | missense_variant | 1.0 | isoniazid | |
| katG | 2155743 | c.369G>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155747 | p.Ala122Gly | missense_variant | 1.0 | isoniazid | |
| pncA | 2290018 | c.-777C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290030 | c.-791_-789delAATinsCC | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290042 | c.-801T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290066 | c.-825G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| kasA | 2517950 | c.-165C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517962 | c.-153C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517968 | c.-147T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>G | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517992 | c.-123C>G | upstream_gene_variant | 0.97 | isoniazid | |
| kasA | 2517993 | c.-122G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518019 | c.-96A>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518025 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518152 | p.Ser13Asn | missense_variant | 0.94 | isoniazid | |
| kasA | 2518162 | c.48G>A | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518168 | c.54C>T | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518172 | c.58_60delACAinsGG | frameshift_variant&missense_variant | 0.96 | isoniazid | |
| kasA | 2518177 | c.63G>A | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 0.97 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518223 | c.109T>C | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518231 | c.117C>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518234 | c.120G>A | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 0.94 | isoniazid | |
| kasA | 2518265 | p.Val51Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518279 | p.Asp55Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518483 | c.369C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518573 | c.459G>C | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 0.9 | isoniazid | |
| kasA | 2518579 | c.465T>C | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2518585 | c.471G>A | synonymous_variant | 0.88 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 0.88 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 0.88 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 0.88 | isoniazid | |
| kasA | 2518612 | c.498C>T | synonymous_variant | 0.85 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 0.86 | isoniazid | |
| kasA | 2518627 | c.513T>C | synonymous_variant | 0.86 | isoniazid | |
| kasA | 2518633 | c.519G>C | synonymous_variant | 0.87 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 0.89 | isoniazid | |
| kasA | 2518651 | c.537C>G | synonymous_variant | 0.89 | isoniazid | |
| kasA | 2518663 | c.549T>C | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518666 | c.552G>A | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518671 | p.Val186Ala | missense_variant | 0.94 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518687 | c.573C>T | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2518688 | p.Val192Phe | missense_variant | 0.98 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2518714 | c.600A>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518717 | c.603C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518759 | c.645C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518765 | c.651G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518807 | c.693C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519167 | c.1053T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519182 | c.1068G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519196 | p.Thr361Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2519203 | c.1089C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519218 | c.1104G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519224 | c.1110C>G | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2519239 | c.1125A>C | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2519260 | c.1146T>G | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2519263 | c.1149C>T | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2519266 | c.1152C>G | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2519269 | c.1155C>T | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2519272 | c.1158C>G | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2519281 | c.1167G>T | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2519287 | c.1173T>C | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2519295 | p.Tyr394Phe | missense_variant | 0.98 | isoniazid | |
| kasA | 2519299 | c.1185C>T | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2519306 | p.Val398Ile | missense_variant | 0.98 | isoniazid | |
| kasA | 2519329 | c.1215C>A | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2519338 | c.1224T>C | synonymous_variant | 0.89 | isoniazid | |
| kasA | 2519347 | c.1233T>C | synonymous_variant | 0.84 | isoniazid | |
| kasA | 2519359 | c.1245T>C | synonymous_variant | 0.82 | isoniazid | |
| ahpC | 2726575 | p.Asp128Gly | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726579 | c.387T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726591 | c.399C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726593 | p.Val134Ala | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726600 | c.408T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726636 | c.444G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726638 | p.Ala149Val | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726642 | c.450C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726651 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726657 | c.465A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726669 | p.Asp159Glu | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726675 | c.483A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726684 |