Run ID: ERR4798504
Sample name:
Date: 2024-10-05T04:33:48.895458
Number of reads: 1995744
Percentage reads mapped: 66.37
Median coverage: 59.0
Strain: lineage3
Spoligotype:
Drug-resistance: RR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage3 | East-African-Indian | RD750 | 1.0 |
La1.7.1 | M.bovis | None | 0.08 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | p.Ser431Cys | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | ||||
ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761097 | p.Ser431Cys | missense_variant | 0.16 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
embB | 4247580 | p.Ala356Val | missense_variant | 0.23 | ethambutol | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 769 | p.Ala257Ser | missense_variant | 0.83 | isoniazid | Uncertain significance |
dnaA | 777 | c.777A>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 792 | c.792C>T | synonymous_variant | 0.18 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.18 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805_807delTTGinsCTT | synonymous_variant | 0.19 | isoniazid | |
dnaA | 819 | c.819C>T | synonymous_variant | 0.23 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.19 | isoniazid | |
dnaA | 846 | c.846T>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
dnaA | 876 | c.876C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 891 | c.891C>T | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 897 | c.897A>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 903 | c.903C>G | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
dnaA | 909 | c.909A>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.15 | isoniazid | |
dnaA | 936 | c.936C>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 939 | c.939C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 942 | c.942C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.17 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 990 | c.990A>C | synonymous_variant | 0.15 | isoniazid | |
dnaA | 996 | c.996A>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.18 | isoniazid | Not assoc w R - Interim |
dnaA | 1020 | c.1020C>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1023 | c.1023C>T | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1029 | c.1029C>T | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1050 | c.1050G>C | synonymous_variant | 0.18 | isoniazid | |
gyrB | 6172 | c.933C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6265 | c.1026C>T | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>A | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6316 | c.-986G>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6326 | p.Ser363Ala | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6331 | c.-971A>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6358 | c.1119C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940_-938delTTGinsCTC | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6911 | p.Asn558His | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6955 | c.-347G>A | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7136 | c.-166T>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7153 | c.-149G>T | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7433 | c.132G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7469 | c.168C>G | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7490 | c.189C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7502 | c.201C>T | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7526 | c.225G>T | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7547 | c.246C>T | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7601 | c.300C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7626 | c.325C>T | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7643 | c.342C>T | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7646 | c.345C>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7655 | c.354G>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7661 | c.360C>T | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7679 | c.378G>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7700 | c.399G>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7706 | c.405C>G | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7725 | c.424C>T | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.42 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7769 | c.468C>T | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7793 | c.492G>A | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7797 | c.496_498delCTAinsTTG | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7820 | c.519G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7832 | c.531G>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7868 | c.567C>T | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8189 | c.888G>C | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8192 | c.891C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8201 | c.900C>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8222 | c.921C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8231 | c.930C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8235 | c.934_936delTTAinsCTG | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | p.Ile328Leu | missense_variant | 0.24 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8489 | c.1188A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8492 | c.1191G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>T | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8535 | p.Glu412Gln | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>T | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8555 | c.1254G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8585 | c.1284C>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8588 | c.1287G>A | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8627 | c.1326C>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8655 | p.Ile452Val | missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8678 | c.1377G>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8694 | c.1393C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8888 | c.1587C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8924 | c.1623C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8930 | c.1629C>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8933 | c.1632G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8936 | c.1635G>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCTC | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8983 | p.Cys561Ser | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.26 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9003 | c.1702C>T | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9038 | c.1737C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9074 | c.1773G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9089 | c.1788G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9101 | c.1800A>G | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9104 | c.1803C>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9266 | c.1965C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9308 | p.Asp669Glu | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9315 | c.2014C>T | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9326 | c.2025G>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9782 | c.2481C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
fgd1 | 490899 | c.117C>T | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490929 | c.147C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490971 | c.189A>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490983 | c.201G>A | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490988 | p.Leu69Gln | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490995 | c.213C>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 490998 | c.216T>G | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R | |||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
ethionamide | ||||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.18 | isoniazid | |
ethionamide | ||||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.24 | isoniazid | |
ethionamide | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.29 | isoniazid | |
ethionamide | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575779 | p.Glu144Asp | missense_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575780 | p.Pro145Ala | missense_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.23 | isoniazid | |
ethionamide | ||||||
mshA | 575842 | c.495G>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575845 | c.498C>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
mshA | 575848 | c.501C>T | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575851 | c.504C>G | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.22 | isoniazid | |
ethionamide | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
mshA | 575887 | c.540G>T | synonymous_variant | 0.17 | isoniazid | |
ethionamide | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.17 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 0.18 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 0.23 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620652 | c.762C>G | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620685 | c.795G>A | synonymous_variant | 0.25 | kanamycin | Not assoc w R - Interim |
capreomycin | Not assoc w R - Interim | |||||
amikacin | ||||||
ccsA | 620698 | p.Val270Ile | missense_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620712 | c.822G>C | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620715 | c.825C>T | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620721 | c.831G>A | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 0.29 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.27 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620742 | c.852G>C | synonymous_variant | 0.26 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
ccsA | 620748 | c.858T>C | synonymous_variant | 0.24 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657189 | c.282C>A | synonymous_variant | 0.17 | ethionamide | |
Rv0565c | 657193 | p.Met93Thr | missense_variant | 0.16 | ethionamide | |
Rv0565c | 657196 | p.Asp92Ala | missense_variant | 0.18 | ethionamide | |
Rv0565c | 657200 | p.Thr91Ala | missense_variant | 0.19 | ethionamide | Uncertain significance |
Rv0565c | 657210 | c.261C>T | synonymous_variant | 0.17 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657213 | c.258C>T | synonymous_variant | 0.17 | ethionamide | |
Rv0565c | 657219 | p.Ala84Val | missense_variant | 0.19 | ethionamide | |
Rv0565c | 657233 | p.Ile80Val | missense_variant | 0.18 | ethionamide | |
Rv0565c | 657240 | p.Glu77Lys | missense_variant | 0.17 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.17 | ethionamide | |
Rv0565c | 657725 | c.-255G>A | upstream_gene_variant | 0.27 | ethionamide | |
Rv0565c | 657732 | c.-263_-262delAGinsGA | upstream_gene_variant | 0.24 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.24 | ethionamide | |
hadA | 731686 | c.-244_-243insATGT | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 731689 | c.-240_-237delAGAC | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 731695 | c.-235C>T | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 731698 | c.-232T>G | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 731708 | c.-222G>A | upstream_gene_variant | 0.27 | isoniazid | |
hadA | 731711 | c.-219T>C | upstream_gene_variant | 0.27 | isoniazid | |
hadA | 731726 | c.-204C>G | upstream_gene_variant | 0.37 | isoniazid | |
hadA | 731729 | c.-201C>T | upstream_gene_variant | 0.37 | isoniazid | |
hadA | 731753 | c.-177A>C | upstream_gene_variant | 0.35 | isoniazid | |
hadA | 731756 | c.-174C>T | upstream_gene_variant | 0.35 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 0.25 | isoniazid | |
hadA | 731786 | c.-144C>G | upstream_gene_variant | 0.25 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 0.26 | isoniazid | |
hadA | 731807 | c.-123C>T | upstream_gene_variant | 0.21 | isoniazid | |
hadA | 731819 | c.-111G>C | upstream_gene_variant | 0.21 | isoniazid | |
hadA | 731843 | c.-87T>C | upstream_gene_variant | 0.21 | isoniazid | |
hadA | 731852 | c.-78A>G | upstream_gene_variant | 0.2 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.2 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.21 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.21 | isoniazid | |
nusG | 734451 | c.198G>C | synonymous_variant | 0.19 | rifampicin | |
nusG | 734454 | c.201A>G | synonymous_variant | 0.19 | rifampicin | |
nusG | 734472 | c.219T>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
nusG | 734475 | c.222T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
nusG | 734478 | c.225C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 0.19 | rifampicin | |
nusG | 734520 | c.267C>A | synonymous_variant | 0.19 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.19 | rifampicin | |
nusG | 734571 | c.318C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 759746 | c.-61C>T | upstream_gene_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 760058 | c.252C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 760070 | c.264T>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760109 | c.303C>T | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760118 | c.312T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.25 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760145 | c.339C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760181 | c.375T>A | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760244 | c.438G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760274 | c.468G>A | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760295 | c.489C>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760358 | c.552C>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.2 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.2 | rifampicin | |
rpoB | 760520 | c.714C>G | synonymous_variant | 0.16 | rifampicin | |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.23 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.25 | rifampicin | |
rpoB | 760601 | c.795C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760622 | c.816C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760748 | c.942C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.18 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760841 | c.1035T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Pro | missense_variant | 0.22 | rifampicin | |
rpoB | 760856 | c.1050C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760916 | c.1110C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760931 | c.1125C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760937 | c.1131G>A | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760973 | c.1167G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760982 | c.1176G>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760985 | c.1179G>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760991 | c.1185G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761006 | c.1200C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761132 | c.1326G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761133 | c.1327_1329delTTGinsCTC | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761240 | c.1434C>T | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761282 | c.1476C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761345 | c.1539G>T | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.35 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.33 | rifampicin | |
rpoB | 761374 | p.Val523Glu | missense_variant | 0.33 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761432 | c.1626C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761438 | c.1632G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761452 | p.Val549Glu | missense_variant | 0.25 | rifampicin | |
rpoB | 761457 | p.Pro551Ser | missense_variant | 0.24 | rifampicin | |
rpoB | 761465 | c.1659G>A | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761471 | c.1665C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761477 | c.1671C>T | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761504 | c.1698C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761558 | c.1752C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761666 | c.1860G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 0.18 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.25 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.25 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.24 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761828 | c.2022C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761913 | p.Asp703Gln | missense_variant | 0.23 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.23 | rifampicin | |
rpoB | 761921 | c.2115C>T | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761930 | c.2124G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.38 | rifampicin | |
rpoB | 762047 | c.2241G>A | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.36 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 762134 | c.2328C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>T | synonymous_variant | 0.29 | rifampicin | |
rpoB | 762254 | c.2448T>G | synonymous_variant | 0.29 | rifampicin | |
rpoB | 762257 | c.2451C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 762281 | c.2475G>A | synonymous_variant | 0.32 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 762341 | c.2535G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.32 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.3 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 762431 | c.2625C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762434 | c.2628T>G | synonymous_variant | 0.71 | rifampicin | Not assoc w R |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762491 | c.2685T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoB | 762510 | p.Ala902Pro | missense_variant | 0.22 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762833 | c.3027C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 762902 | c.-468C>T | upstream_gene_variant | 0.31 | rifampicin | |
rpoC | 762917 | c.-453C>T | upstream_gene_variant | 0.3 | rifampicin | |
rpoB | 762929 | c.3123G>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762962 | c.3156C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 762983 | c.-387C>G | upstream_gene_variant | 0.27 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763050 | c.-320C>T | upstream_gene_variant | 0.3 | rifampicin | |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763082 | c.3276C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 763205 | c.-165G>T | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 763241 | c.-129G>A | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 763402 | c.33C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763441 | c.72C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763618 | c.249C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763669 | c.300C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763703 | c.334_336delTCGinsAGC | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763726 | c.357C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763765 | c.396T>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763771 | c.402C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763792 | p.Glu141Asp | missense_variant | 0.22 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763836 | p.Ala156Val | missense_variant | 0.2 | rifampicin | |
rpoC | 763851 | p.Ala161Gly | missense_variant | 0.25 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.29 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.29 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763951 | c.582G>A | synonymous_variant | 0.37 | rifampicin | |
rpoC | 763963 | c.594C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763967 | p.Gly200Ser | missense_variant | 0.35 | rifampicin | |
rpoC | 763972 | c.603C>T | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763987 | c.618C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.3 | rifampicin | |
rpoC | 764044 | c.675T>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764159 | c.790C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764167 | c.798G>A | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Ile | missense_variant | 0.26 | rifampicin | |
rpoC | 764215 | c.846A>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764218 | c.849C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764242 | c.873C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764245 | c.876C>A | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764246 | c.877_879delCTCinsTTG | synonymous_variant | 0.26 | rifampicin | |
rpoC | 764263 | c.894G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764317 | c.948C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764320 | c.951C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764428 | c.1059G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764554 | c.1185C>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764593 | c.1224C>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764605 | c.1236G>A | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764668 | c.1299C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764686 | c.1317C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764782 | c.1413C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764797 | c.1428G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764803 | c.1434C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764887 | c.1518G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519_1521delTTGinsCTC | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764896 | c.1527C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764902 | c.1533C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765013 | c.1644C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765019 | c.1650A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765052 | c.1683C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765053 | c.1684_1686delTCCinsAGT | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765065 | c.1696C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765079 | c.1710T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>A | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765121 | c.1752G>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 765367 | c.1998C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765370 | c.2001G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoC | 765391 | c.2022C>T | synonymous_variant | 0.22 | rifampicin | |
rpoC | 765406 | c.2037G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765452 | p.Ala695Ser | missense_variant | 0.28 | rifampicin | |
rpoC | 765466 | c.2097C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765493 | c.2124G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765517 | c.2148C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765529 | c.2160C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765562 | c.2193G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765622 | p.Glu751Asp | missense_variant | 0.4 | rifampicin | |
rpoC | 765625 | c.2256C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765670 | c.2301C>T | synonymous_variant | 0.41 | rifampicin | |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 765728 | p.Gln787Lys | missense_variant | 0.41 | rifampicin | |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765752 | p.Asp795Ser | missense_variant | 0.41 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765790 | c.2421C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765934 | c.2565C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 766012 | c.2643C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766061 | p.Val898Ile | missense_variant | 0.34 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.26 | rifampicin | |
rpoC | 766093 | c.2724C>A | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766095 | p.Thr909Ser | missense_variant | 0.23 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766123 | c.2754C>A | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766402 | c.3033C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766456 | c.3087C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.38 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766585 | c.3216T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.37 | rifampicin | |
rpoC | 766630 | c.3261G>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766660 | c.3291G>A | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766700 | c.3331C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766733 | c.3364C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766738 | c.3369G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766741 | c.3372G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766798 | c.3429C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 766801 | c.3432C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.43 | rifampicin | |
rpoC | 766876 | c.3507C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 766883 | p.Ser1172Ala | missense_variant | 0.4 | rifampicin | Uncertain significance |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766903 | c.3534C>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.25 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>A | synonymous_variant | 0.2 | rifampicin | |
rpoC | 767158 | c.3789T>A | synonymous_variant | 0.29 | rifampicin | |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.3 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.15 | bedaquiline | |
clofazimine | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781658 | c.99A>G | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781718 | c.159C>G | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781721 | c.162C>T | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781766 | c.207C>T | synonymous_variant | 0.3 | streptomycin | Not assoc w R - Interim |
rpsL | 781772 | c.213C>G | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.28 | streptomycin | |
rpsL | 781832 | c.273T>G | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781835 | c.276T>C | synonymous_variant | 0.3 | streptomycin | Not assoc w R - Interim |
rpsL | 781859 | c.300T>G | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781883 | c.324G>A | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781886 | c.327C>T | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.23 | streptomycin | Uncertain significance |
rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 0.22 | streptomycin | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800579 | c.-230C>T | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800582 | c.-227C>T | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800621 | c.-188G>A | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800627 | c.-182C>T | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800648 | c.-161A>G | upstream_gene_variant | 0.33 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.32 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800714 | c.-95C>T | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800744 | c.-65G>C | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800745 | c.-64_-62delCTCinsTTG | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800759 | c.-50C>T | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800762 | c.-47T>G | upstream_gene_variant | 0.24 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
fbiC | 1303488 | c.558G>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303506 | c.576C>T | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303538 | p.Arg203Leu | missense_variant | 0.28 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303578 | c.648G>A | synonymous_variant | 0.31 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303596 | c.666G>C | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303620 | c.690C>T | synonymous_variant | 0.26 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303629 | c.699C>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.3 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303661 | p.Val244Ala | missense_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.27 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303704 | c.774T>C | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303729 | c.799_801delCTAinsTTG | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303750 | c.820_822delTTAinsCTG | synonymous_variant | 0.24 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303779 | c.849G>A | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303782 | c.852C>T | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303788 | c.858T>C | synonymous_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303789 | p.Ile287Val | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303800 | c.870G>C | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303812 | c.882C>T | synonymous_variant | 0.29 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.25 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303825 | p.Glu299Gln | missense_variant | 0.26 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303844 | p.Ala305Gly | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.22 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.23 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303860 | c.930A>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303869 | c.939T>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | Not assoc w R - Interim | |||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1303905 | c.975G>C | synonymous_variant | 0.2 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303913 | p.Gly328Asp | missense_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303920 | c.990C>G | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1303923 | c.993C>T | synonymous_variant | 0.21 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304481 | c.1551T>G | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304496 | c.1566T>A | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304499 | c.1569T>G | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | Not assoc w R - Interim | |||||
fbiC | 1304502 | c.1572G>C | synonymous_variant | 0.17 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304532 | c.1602G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304533 | c.1603T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304541 | c.1611C>G | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304546 | p.Val539Ala | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.19 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304610 | c.1680C>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304613 | c.1683T>A | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304934 | c.2004C>G | synonymous_variant | 0.15 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.18 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.16 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
fbiC | 1305364 | p.Met812Leu | missense_variant | 0.9 | pretomanid | |
delamanid | ||||||
clofazimine | ||||||
sigE | 1364703 | c.291G>C | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364712 | c.300T>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364721 | c.309C>G | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364726 | p.Asn105Ser | missense_variant | 0.22 | pyrazinamide | |
sigE | 1364733 | p.His107Gln | missense_variant | 0.2 | pyrazinamide | |
sigE | 1364736 | c.324T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364742 | c.330A>G | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364745 | c.333C>T | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364746 | c.334C>T | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364751 | c.339C>G | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364760 | c.348C>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364763 | c.351T>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364767 | c.355A>C | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364790 | c.378T>C | synonymous_variant | 0.27 | pyrazinamide | |
sigE | 1364799 | c.387G>C | synonymous_variant | 0.3 | pyrazinamide | |
sigE | 1364802 | c.390C>A | synonymous_variant | 0.34 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.33 | pyrazinamide | |
sigE | 1364820 | c.408A>G | synonymous_variant | 0.35 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.3 | pyrazinamide | |
sigE | 1364847 | c.435G>C | synonymous_variant | 0.29 | pyrazinamide | |
sigE | 1364856 | c.444C>G | synonymous_variant | 0.25 | pyrazinamide | |
sigE | 1364868 | c.456T>C | synonymous_variant | 0.28 | pyrazinamide | |
sigE | 1364871 | c.459C>G | synonymous_variant | 0.28 | pyrazinamide | |
sigE | 1364874 | c.462C>T | synonymous_variant | 0.28 | pyrazinamide | |
sigE | 1364883 | c.471G>A | synonymous_variant | 0.3 | pyrazinamide | |
sigE | 1364889 | c.477A>G | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364892 | c.480C>G | synonymous_variant | 0.29 | pyrazinamide | |
sigE | 1364913 | c.501C>G | synonymous_variant | 0.33 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.32 | pyrazinamide | |
sigE | 1364925 | c.513C>G | synonymous_variant | 0.34 | pyrazinamide | |
sigE | 1364928 | c.516C>T | synonymous_variant | 0.34 | pyrazinamide | |
sigE | 1364952 | c.540A>C | synonymous_variant | 0.26 | pyrazinamide | |
sigE | 1364958 | c.546G>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364961 | c.549A>G | synonymous_variant | 0.22 | pyrazinamide | |
sigE | 1364964 | c.552T>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364967 | c.555C>T | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364973 | c.561G>A | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364976 | c.564T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364984 | p.Ala191Asp | missense_variant | 0.19 | pyrazinamide | |
sigE | 1364988 | c.576G>A | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
sigE | 1365003 | c.591T>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1365006 | c.594T>C | synonymous_variant | 0.19 | pyrazinamide | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472031 | n.186G>T | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.18 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472040 | n.195T>C | non_coding_transcript_exon_variant | 0.21 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.27 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472686 | n.841G>A | non_coding_transcript_exon_variant | 0.35 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472848 | n.1003T>G | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472859 | n.1014G>C | non_coding_transcript_exon_variant | 0.17 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 0.17 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.23 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.24 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.29 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.3 | kanamycin | |
capreomycin | ||||||
streptomycin | ||||||
amikacin | ||||||
rrs | 1473288 | n.1443C>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 0.26 | kanamycin | Uncertain significance |
capreomycin | Uncertain significance | |||||
streptomycin | ||||||
amikacin | Uncertain significance | |||||
rrl | 1473831 | n.174G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474447 | n.790G>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475453 | n.1796T>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475487 | n.1830C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.31 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475760 | n.2103C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475999 | n.2342G>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1476047 | n.2390G>A | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
inhA | 1673758 | c.-444A>G | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1673784 | c.-418G>C | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1673793 | c.-409G>A | upstream_gene_variant | 0.16 | isoniazid | |
ethionamide | ||||||
inhA | 1673799 | c.-403T>C | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673802 | c.-400A>G | upstream_gene_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1673808 | c.-394A>G | upstream_gene_variant | 0.17 | isoniazid | |
ethionamide | ||||||
inhA | 1673841 | c.-361A>G | upstream_gene_variant | 0.16 | isoniazid | |
ethionamide | ||||||
inhA | 1673856 | c.-346T>G | upstream_gene_variant | 0.18 | isoniazid | |
ethionamide | ||||||
inhA | 1673877 | c.-325C>T | upstream_gene_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674745 | p.Tyr182Ala | missense_variant | 0.19 | isoniazid | |
ethionamide | ||||||
inhA | 1674756 | c.555T>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
ethionamide | Not assoc w R - Interim | |||||
inhA | 1674759 | c.558G>C | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674765 | c.564C>T | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674774 | c.573A>C | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674777 | c.576C>A | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 0.26 | isoniazid | |
ethionamide | ||||||
inhA | 1674792 | c.591G>C | synonymous_variant | 0.27 | isoniazid | |
ethionamide | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674820 | c.619_621delCTCinsTTG | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674828 | c.627G>A | synonymous_variant | 0.25 | isoniazid | |
ethionamide | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 0.28 | isoniazid | |
ethionamide | ||||||
inhA | 1674870 | c.669T>C | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674876 | c.675C>G | synonymous_variant | 0.21 | isoniazid | |
ethionamide | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.2 | isoniazid | |
ethionamide | ||||||
inhA | 1674888 | c.687C>T | synonymous_variant | 0.16 | isoniazid | |
ethionamide | ||||||
rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.18 | pyrazinamide | |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833613 | c.72C>A | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.35 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833703 | c.162C>T | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1833760 | c.219C>T | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833790 | c.249T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833802 | c.261A>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833808 | c.267G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833859 | c.318C>T | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833895 | c.354G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833964 | c.423C>T | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833970 | c.429G>A | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.17 | pyrazinamide | |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834186 | c.645C>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834225 | c.684C>G | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1834231 | c.690T>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834297 | c.756C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834336 | c.795C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834357 | c.816T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834396 | c.855G>T | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834423 | c.882G>T | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834456 | c.915T>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834477 | c.936C>T | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834519 | c.978G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834603 | c.1062G>A | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834612 | c.1071G>A | synonymous_variant | 0.29 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834654 | c.1113G>A | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834699 | p.Glu386Asp | missense_variant | 0.24 | pyrazinamide | |
tsnR | 1853369 | c.-237C>T | upstream_gene_variant | 0.31 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 0.32 | linezolid | |
tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 0.31 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.32 | linezolid | |
tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 0.32 | linezolid | |
tsnR | 1853393 | c.-213C>T | upstream_gene_variant | 0.33 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.33 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.34 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.32 | linezolid | |
tsnR | 1853441 | c.-165C>G | upstream_gene_variant | 0.33 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.31 | linezolid | |
tsnR | 1853450 | c.-156G>A | upstream_gene_variant | 0.29 | linezolid | |
tsnR | 1853453 | c.-153G>C | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.24 | linezolid | |
tsnR | 1853481 | c.-125A>G | upstream_gene_variant | 0.21 | linezolid | |
tsnR | 1853485 | c.-121G>C | upstream_gene_variant | 0.2 | linezolid | |
tsnR | 1853493 | c.-113G>A | upstream_gene_variant | 0.18 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 0.95 | pyrazinamide | Not assoc w R |
PPE35 | 2169208 | c.1404delC | frameshift_variant | 1.0 | pyrazinamide | Uncertain significance |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
clofazimine | Not assoc w R | |||||
pncA | 2289047 | c.195C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R |
pncA | 2289365 | c.-125delC | upstream_gene_variant | 1.0 | pyrazinamide | |
kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.25 | isoniazid | |
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.23 | isoniazid | |
kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.26 | isoniazid | |
kasA | 2517965 | c.-150C>T | upstream_gene_variant | 0.25 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.25 | isoniazid | |
kasA | 2517983 | c.-132T>C | upstream_gene_variant | 0.22 | isoniazid | |
kasA | 2517989 | c.-126T>G | upstream_gene_variant | 0.22 | isoniazid | |
kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.2 | isoniazid | |
kasA | 2518594 | c.480C>T | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518597 | c.483C>G | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518606 | c.492G>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.17 | isoniazid | |
kasA | 2518636 | c.522C>A | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518639 | c.525G>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518645 | c.531G>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518651 | c.537C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518657 | c.543G>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518717 | c.603C>G | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518735 | c.621C>T | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2519112 | p.Gln333Arg | missense_variant | 0.2 | isoniazid | |
kasA | 2519119 | c.1005G>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2519134 | c.1020G>A | synonymous_variant | 0.22 | isoniazid | |
kasA | 2519137 | c.1023T>G | synonymous_variant | 0.22 | isoniazid | |
kasA | 2519140 | c.1026G>A | synonymous_variant | 0.21 | isoniazid | |
kasA | 2519146 | c.1032C>A | synonymous_variant | 0.21 | isoniazid | |
kasA | 2519152 | c.1038G>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2519161 | c.1047G>A | synonymous_variant | 0.2 | isoniazid | |
kasA | 2519167 | c.1053T>G | synonymous_variant | 0.17 | isoniazid | |
ahpC | 2726105 | c.-88G>A | upstream_gene_variant | 1.0 | isoniazid | Not assoc w R |
Rv2477c | 2782498 | c.1545C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
Rv2477c | 2783410 | c.633G>C | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783419 | c.624G>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783458 | c.585G>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.18 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.23 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783535 | c.508C>T | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783542 | c.501G>A | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>G | synonymous_variant | 0.23 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783563 | c.480A>C | synonymous_variant | 0.21 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783572 | c.471A>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783578 | c.465G>A | synonymous_variant | 0.24 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783602 | c.441G>A | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783623 | c.420G>A | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783632 | c.411C>G | synonymous_variant | 0.22 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.19 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783691 | c.352C>T | synonymous_variant | 0.17 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783788 | c.255T>G | synonymous_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.16 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783806 | c.237G>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783857 | c.186C>G | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783860 | c.183T>C | synonymous_variant | 0.17 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783920 | c.123G>T | synonymous_variant | 0.35 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783938 | c.105T>C | synonymous_variant | 0.3 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783956 | p.Tyr29Phe | missense_variant | 0.25 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.25 | kanamycin | Not assoc w R - Interim |
levofloxacin | ||||||
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783968 | c.75G>C | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.26 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.27 | kanamycin | |
levofloxacin | ||||||
moxifloxacin | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.26 | kanamycin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2752c | 3065040 | c.1150_1152delCTCinsTTG | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065049 | c.1143G>A | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065055 | c.1137T>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065070 | c.1122C>A | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065085 | c.1105_1107delAGGinsCGC | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065097 | c.1095C>T | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065109 | c.1081_1083delAGAinsCGG | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065130 | c.1062A>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
ethambutol | Not assoc w R - Interim | |||||
Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065154 | c.1038G>A | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
ethambutol | Uncertain significance | |||||
Rv2752c | 3065994 | c.198T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3065997 | c.195C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066006 | c.186G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066017 | c.175C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066024 | c.168T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066365 | c.-174C>T | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066366 | c.-175C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066387 | c.-196G>A | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066420 | c.-229C>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066423 | c.-232C>T | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066426 | c.-235T>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066429 | c.-238G>A | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066432 | c.-241T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066437 | c.-246G>A | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066459 | c.-268T>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066465 | c.-276_-274delGGGinsAGC | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066471 | c.-280A>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066474 | c.-283G>C | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066477 | c.-286C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066480 | c.-291_-289delGCCinsTCT | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066483 | c.-292T>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066513 | c.-322C>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066527 | c.-336C>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066543 | c.-352C>A | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066560 | c.-369C>T | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066567 | c.-376C>A | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066612 | c.-421G>A | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
Rv2752c | 3066618 | c.-427A>G | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
rifampicin | ||||||
ethambutol | ||||||
thyX | 3067661 | c.285C>A | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067676 | c.270C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067679 | p.Cys89Leu | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067693 | p.Ile85Val | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067742 | c.204A>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067761 | p.Arg62Lys | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067793 | c.153T>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067841 | c.105G>T | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyX | 3067886 | c.60A>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067949 | c.-4C>T | upstream_gene_variant | 0.93 | para-aminosalicylic_acid | |
thyA | 3073854 | c.618C>T | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyA | 3073863 | c.609T>C | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyA | 3073888 | p.Ser195Glu | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073905 | c.567C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073944 | c.528C>T | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073956 | c.516G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3073959 | c.513T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3073968 | c.504C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
whiB7 | 3568857 | c.-178C>T | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
streptomycin | Uncertain significance | |||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625147 | c.-237C>G | upstream_gene_variant | 0.16 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625690 | c.-780T>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625699 | c.915C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625717 | c.-807C>T | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625747 | c.867G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625783 | c.-873C>T | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
lpqB | 3625801 | c.-891G>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626332 | c.282T>C | synonymous_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626344 | c.270G>C | synonymous_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626349 | p.Ser89Gly | missense_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626353 | c.261C>G | synonymous_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626362 | c.252A>C | synonymous_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626368 | c.246G>A | synonymous_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626377 | p.Asp79Glu | missense_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626383 | p.Ala77Gly | missense_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626389 | p.Arg75Lys | missense_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626400 | p.Ile72Val | missense_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626404 | c.210C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3626407 | c.207C>G | synonymous_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626437 | c.177T>C | synonymous_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626443 | c.171T>G | synonymous_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626451 | c.163C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626455 | c.159C>G | synonymous_variant | 0.18 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626461 | c.153A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626470 | c.144A>C | synonymous_variant | 0.15 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 0.17 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626777 | c.573C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.19 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3626825 | c.525T>A | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626843 | c.-230G>A | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626849 | c.-236C>T | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 0.2 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626885 | c.-272A>G | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrA | 3626912 | c.438T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3626924 | c.-311G>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626927 | c.-314G>A | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626933 | c.-320C>T | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 0.3 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3626996 | c.-383G>A | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627023 | c.-410C>G | upstream_gene_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627059 | c.-446G>C | upstream_gene_variant | 0.33 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627098 | c.252A>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627101 | c.-488C>G | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.31 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 0.32 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 0.37 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627137 | c.-526_-524delTTGinsCTA | upstream_gene_variant | 0.34 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627143 | c.-530G>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 0.35 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 0.29 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627187 | c.163T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
bedaquiline | ||||||
mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 0.26 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.27 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627212 | c.-599C>T | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627218 | c.-605G>C | upstream_gene_variant | 0.28 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627233 | c.-620T>G | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.23 | rifampicin | |
bedaquiline | ||||||
mtrA | 3627239 | c.111C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.24 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.25 | rifampicin | |
bedaquiline | ||||||
mtrB | 3627272 | c.-659G>C | upstream_gene_variant | 0.21 | rifampicin | |
bedaquiline | ||||||
rpoA | 3877587 | c.921A>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.27 | rifampicin | |
rpoA | 3877617 | c.891G>C | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3877638 | c.870T>G | synonymous_variant | 0.28 | rifampicin | |
rpoA | 3877656 | c.852T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877677 | p.Ala277Ser | missense_variant | 0.21 | rifampicin | |
rpoA | 3877680 | c.828G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877685 | c.823C>T | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3877737 | c.771G>C | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3877758 | c.750G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoA | 3877815 | c.693C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoA | 3877851 | c.657C>T | synonymous_variant | 0.32 | rifampicin | |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.33 | rifampicin | |
rpoA | 3877865 | c.643C>T | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoA | 3877887 | c.621G>C | synonymous_variant | 0.27 | rifampicin | |
rpoA | 3877900 | p.Ser203Thr | missense_variant | 0.21 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.22 | rifampicin | |
rpoA | 3877920 | c.588G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoA | 3878295 | c.213A>G | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878331 | c.177A>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878364 | c.144A>C | synonymous_variant | 0.25 | rifampicin | |
rpoA | 3878370 | c.138T>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878384 | c.124C>T | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878391 | c.117T>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3878418 | c.90C>T | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878454 | c.54A>G | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3878824 | c.-317G>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3878836 | c.-329G>C | upstream_gene_variant | 0.24 | rifampicin | Uncertain significance |
rpoA | 3878842 | c.-335G>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3878869 | c.-362G>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 0.29 | rifampicin | Uncertain significance |
rpoA | 3878881 | c.-374C>G | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3878894 | c.-387A>G | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 0.34 | rifampicin | |
rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 0.37 | rifampicin | Uncertain significance |
rpoA | 3878923 | c.-417_-416delGCinsCG | upstream_gene_variant | 0.37 | rifampicin | |
rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 0.4 | rifampicin | Uncertain significance |
rpoA | 3878953 | c.-446C>G | upstream_gene_variant | 0.39 | rifampicin | |
rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 0.34 | rifampicin | Uncertain significance |
rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 0.29 | rifampicin | Uncertain significance |
rpoA | 3879037 | c.-530G>A | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3879049 | c.-542A>G | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoA | 3879117 | c.-610C>T | upstream_gene_variant | 0.31 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.29 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879145 | c.-638G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoA | 3879148 | c.-641G>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879178 | c.-671T>G | upstream_gene_variant | 0.2 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.18 | rifampicin | |
clpC1 | 4038425 | c.2280C>A | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038456 | p.Val750Glu | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4038486 | p.Gly740Asn | missense_variant | 0.19 | pyrazinamide | |
clpC1 | 4038491 | c.2214C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038502 | p.Ile735Val | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4038508 | c.2197C>T | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038518 | c.2187G>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.18 | pyrazinamide | |
clpC1 | 4038537 | p.Thr723Ser | missense_variant | 0.18 | pyrazinamide | |
clpC1 | 4038539 | c.2166G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038569 | c.2136C>T | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038620 | c.2085G>A | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038692 | c.2013C>G | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038698 | c.2007C>T | synonymous_variant | 0.17 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038749 | c.1956C>T | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038809 | c.1896G>A | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038875 | c.1830C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038893 | c.1812C>T | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.38 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.41 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.37 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039004 | c.1701C>G | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039025 | c.1680C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039067 | c.1638G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>T | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>A | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039183 | c.1522T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039190 | c.1515C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039193 | c.1512C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039223 | c.1482C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039226 | c.1479T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039238 | c.1467C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039243 | c.1462C>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039259 | c.1446G>A | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039262 | c.1443C>T | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039268 | c.1437C>T | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039286 | c.1419T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039298 | c.1407T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039304 | c.1401G>A | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039484 | c.1221T>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039508 | c.1197G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039526 | c.1179G>A | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039532 | c.1173C>T | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039553 | c.1152C>A | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039565 | c.1140G>C | synonymous_variant | 0.32 | pyrazinamide | |
clpC1 | 4039576 | p.Ala377Ser | missense_variant | 0.31 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039583 | c.1122C>T | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>T | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039664 | c.1041G>C | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4039670 | c.1035G>C | synonymous_variant | 0.33 | pyrazinamide | |
clpC1 | 4039694 | c.1011G>C | synonymous_variant | 0.39 | pyrazinamide | |
clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039739 | c.966C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039742 | c.963C>T | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039748 | c.957G>A | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039769 | c.936C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039817 | c.888A>T | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039820 | c.885T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039831 | c.874T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039832 | c.873C>T | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039937 | c.768G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039943 | c.762G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039946 | c.759A>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039949 | c.756G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039955 | c.750G>T | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039964 | c.741C>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4040000 | c.705C>T | synonymous_variant | 0.34 | pyrazinamide | |
clpC1 | 4040015 | c.690G>A | synonymous_variant | 0.35 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040024 | c.681A>G | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.35 | pyrazinamide | |
clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040093 | c.612C>G | synonymous_variant | 0.31 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040105 | c.600C>G | synonymous_variant | 0.3 | pyrazinamide | |
clpC1 | 4040147 | c.558A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040171 | c.534C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040213 | p.Ser164Thr | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4040246 | c.459C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040249 | c.456A>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040267 | c.438A>G | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040273 | c.432T>C | synonymous_variant | 0.34 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.31 | pyrazinamide | |
clpC1 | 4040309 | c.396C>T | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040348 | c.357G>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040363 | c.342A>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040375 | c.330G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040419 | c.286C>T | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040426 | c.279T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040486 | c.219G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040495 | c.210C>A | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.3 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.29 | pyrazinamide | |
clpC1 | 4040573 | c.132T>A | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4040579 | c.126A>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040582 | c.123G>C | synonymous_variant | 0.22 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040588 | c.117T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4040597 | c.108C>T | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040600 | c.103_105delTTAinsCTG | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4040603 | c.102T>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.22 | pyrazinamide | |
panD | 4044023 | c.259C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R |
panD | 4044872 | c.-591C>T | upstream_gene_variant | 0.93 | pyrazinamide | |
glpK | 4138622 | c.1134C>T | synonymous_variant | 0.88 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
ethambutol | Not assoc w R | |||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138681 | p.Met359Val | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
glpK | 4138682 | c.1074C>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
isoniazid | ||||||
streptomycin | ||||||
rifampicin | ||||||
ethambutol | ||||||
embC | 4240642 | c.780G>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4240645 | c.783G>C | synonymous_variant | 0.16 | ethambutol | |
embC | 4240657 | c.795G>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4240660 | c.798C>G | synonymous_variant | 0.18 | ethambutol | |
embC | 4240671 | p.Thr270Ile | missense_variant | 0.18 | ethambutol | Not assoc w R |
embC | 4240678 | c.816T>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4240681 | c.819G>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4240685 | p.Thr275Ala | missense_variant | 0.19 | ethambutol | |
embC | 4240690 | c.828G>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4240693 | c.831T>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4240698 | p.Ala279Gly | missense_variant | 0.17 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
embC | 4240729 | c.867C>G | synonymous_variant | 0.19 | ethambutol | |
embC | 4242075 | p.Arg738Gln | missense_variant | 1.0 | ethambutol | Not assoc w R |
embC | 4242309 | p.Thr816Ile | missense_variant | 1.0 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4245125 | c.1893G>C | synonymous_variant | 0.18 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4247500 | c.987C>G | synonymous_variant | 0.21 | ethambutol | |
embB | 4247506 | c.993C>G | synonymous_variant | 0.25 | ethambutol | |
embB | 4247512 | c.999T>C | synonymous_variant | 0.25 | ethambutol | |
embB | 4247527 | c.1014G>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4247539 | c.1026T>C | synonymous_variant | 0.2 | ethambutol | |
embB | 4247550 | p.Ala346Asp | missense_variant | 0.21 | ethambutol | |
embB | 4247554 | c.1041T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4247566 | c.1053C>G | synonymous_variant | 0.23 | ethambutol | |
embB | 4247572 | c.1059A>C | synonymous_variant | 0.21 | ethambutol | |
embB | 4247590 | c.1077A>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embB | 4247629 | c.1116C>G | synonymous_variant | 0.16 | ethambutol | |
embB | 4247632 | c.1119C>G | synonymous_variant | 0.15 | ethambutol | |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.22 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.19 | ethambutol | |
embB | 4248118 | c.1605T>G | synonymous_variant | 0.18 | ethambutol | |
embB | 4248127 | c.1614G>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4248190 | c.1677G>C | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
embB | 4248200 | p.Ile563Val | missense_variant | 0.18 | ethambutol | |
embB | 4248206 | p.Ser565Gly | missense_variant | 0.17 | ethambutol | Uncertain significance |
embB | 4248211 | c.1698G>A | synonymous_variant | 0.16 | ethambutol | |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | kanamycin | Not assoc w R |
capreomycin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | kanamycin | |
capreomycin | ||||||
amikacin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin | Not assoc w R |