TB-Profiler result

Run: ERR4797184
Summary

Run ID: ERR4797184

Sample name:

Date: 2024-03-25T23:08:25.132652

Number of reads: 602522

Percentage reads mapped: 12.33

Median coverage: 2.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.99
lineage4.9 Euro-American (H37Rv-like) None 0.91
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG c.346_348delCACinsGG Assoc w R High-level resistance
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.766_768delGCTinsCC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.838_840delATCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491548 c.766_768delGCTinsCC frameshift_variant&missense_variant 0.78 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491620 c.838_840delATCinsGG frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155764 c.346_348delCACinsGG frameshift_variant&missense_variant 0.73 isoniazid Assoc w R High-level resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 693 c.693A>C synonymous_variant 0.91 isoniazid
dnaA 702 c.702C>G synonymous_variant 0.85 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.85 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.85 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.95 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.95 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.95 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.95 isoniazid
dnaA 769 c.769_771delGCAinsTG frameshift_variant&stop_gained 0.95 isoniazid Uncertain significance
dnaA 783 c.783C>T synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.95 isoniazid Uncertain significance
dnaA 799 c.799_801delGTGinsAC frameshift_variant&missense_variant 0.95 isoniazid Uncertain significance
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.95 isoniazid Uncertain significance
dnaA 822 c.822A>G synonymous_variant 0.95 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.94 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.92 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.91 isoniazid
dnaA 1086 c.1086C>G synonymous_variant 0.93 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.93 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.93 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.93 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.93 isoniazid
dnaA 1122 c.1122C>T synonymous_variant 0.93 isoniazid
dnaA 1126 c.1126C>T synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 1137 c.1137C>G synonymous_variant 0.93 isoniazid
dnaA 1140 c.1140C>G synonymous_variant 0.93 isoniazid
dnaA 1143 c.1143G>C synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153_1155delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1166 p.Pro389Arg missense_variant 1.0 isoniazid
dnaA 1176 c.1176A>G synonymous_variant 1.0 isoniazid
dnaA 1179 c.1179G>A synonymous_variant 1.0 isoniazid
dnaA 1188 c.1188G>A synonymous_variant 1.0 isoniazid
dnaA 1189 c.1189_1191delATTinsGC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1195 c.1195_1197delCTTinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1220 p.Asn407Thr missense_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1314 c.1314A>T synonymous_variant 0.92 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.92 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 0.91 isoniazid
dnaA 1332 c.1332A>T synonymous_variant 0.91 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 0.91 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 0.91 isoniazid
gyrB 6175 c.936G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6196 c.957C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGT synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6227 p.Lys330Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6241 p.Asp334Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6283 p.Asp348Glu missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6589 c.-713G>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.62 levofloxacin
moxifloxacin
gyrA 6601 c.-701A>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6607 c.-695T>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>A upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.87 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6838 c.-464C>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6844 c.-458T>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7126 c.-176G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7159 c.1920C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7162 c.1923C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7243 c.-59G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7418 c.117C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7601 c.300C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7673 c.372G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8366 c.1065G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364Leu missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8456 c.1155C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8540 c.1239C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8628 c.1327C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8649 p.Arg450Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8663 c.1362C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8696 c.1395G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9017 c.1716C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9038 c.1737C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 491043 c.261T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491055 c.273C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491073 c.291C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491077 p.Asn99Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491085 c.303T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491490 c.708C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491536 c.754C>T synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491562 c.780C>T synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491571 c.789C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
mshA 575725 c.378C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575764 c.417C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575795 p.Ile150Val missense_variant 1.0 ethionamide
isoniazid
mshA 575800 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575803 c.456C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575821 c.474G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620337 c.447C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620358 c.468C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620362 c.472_474delGCCinsTG frameshift_variant&missense_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620385 c.495G>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620397 c.507C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.92 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620421 c.531G>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620427 c.537C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620442 c.552G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620454 c.564C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620619 c.729G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620764 c.874_876delGCCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620781 c.891C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 657636 c.-167_-166delAGinsTC upstream_gene_variant 0.91 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.91 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.91 ethionamide
Rv0565c 657668 c.-200_-198delACCinsGG upstream_gene_variant 0.91 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.91 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.91 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 0.91 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.91 ethionamide
Rv0565c 657703 c.-233C>A upstream_gene_variant 0.91 ethionamide
Rv0565c 657722 c.-254_-252delAACinsCG upstream_gene_variant 0.94 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.94 ethionamide
nusG 734424 c.171G>C synonymous_variant 0.82 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.92 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.94 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.94 rifampicin
nusG 734460 c.207G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.9 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.86 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.82 rifampicin
rpoB 760046 c.240G>C synonymous_variant 0.83 rifampicin
rpoB 760059 c.253_255delTACinsGA frameshift_variant&missense_variant 0.84 rifampicin
rpoB 760067 c.261G>C synonymous_variant 0.91 rifampicin
rpoB 760070 c.264T>C synonymous_variant 0.92 rifampicin
rpoB 760082 c.276C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 0.9 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 0.9 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.93 rifampicin
rpoB 760118 c.312T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.94 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 0.95 rifampicin
rpoB 760139 c.333A>T synonymous_variant 0.95 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.95 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.99 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.99 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.99 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.99 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.98 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 1.0 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 1.0 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 1.0 rifampicin
rpoB 760571 c.765G>C synonymous_variant 1.0 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760595 c.789C>T synonymous_variant 1.0 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760755 c.949_951delCATinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760784 c.978G>T synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.97 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.97 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.91 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 0.9 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 0.89 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 0.84 rifampicin
rpoB 760887 p.Thr361Val missense_variant 0.89 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 0.88 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.88 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.86 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.86 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.92 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.92 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 761087 c.1281C>G synonymous_variant 0.69 rifampicin
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.69 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.69 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.76 rifampicin
rpoB 761111 c.1305C>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.97 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.98 rifampicin
rpoB 761288 c.1482G>T synonymous_variant 0.98 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.95 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.95 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.93 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.92 rifampicin
rpoB 761366 c.1560C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761367 p.Glu521Gln missense_variant 0.92 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.92 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.83 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>C synonymous_variant 0.95 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.96 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.96 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.94 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.94 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.94 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 0.97 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.96 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 0.93 rifampicin
rpoB 761712 p.Val636Ile missense_variant 0.92 rifampicin
rpoB 761718 c.1912_1913delGCinsT frameshift_variant&missense_variant 0.9 rifampicin
rpoB 761722 p.Glu639Gly missense_variant 0.86 rifampicin Uncertain significance
rpoB 761727 p.Ser641Gly missense_variant 0.91 rifampicin
rpoB 761732 c.1926_1927delCGinsGCA frameshift_variant&missense_variant 0.9 rifampicin
rpoB 761736 p.Ile644Val missense_variant 0.91 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 0.91 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.9 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.95 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761785 p.Thr660Ser missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.97 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.95 rifampicin
rpoB 761847 c.2041_2043delTGCinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 1.0 rifampicin
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.97 rifampicin
rpoB 761892 p.Ile696Val missense_variant 0.97 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.96 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.96 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.96 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.96 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.96 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.97 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.97 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.98 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 1.0 rifampicin
rpoB 762287 c.2481C>T synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 0.96 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.96 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.96 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.96 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 0.96 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.96 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.96 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.96 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.96 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.96 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.96 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.97 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 0.97 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.97 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762515 c.2709C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 0.94 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.93 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.93 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.88 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 1.0 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 1.0 rifampicin
rpoC 763199 c.-171G>C upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-163delAGinsTC upstream_gene_variant 1.0 rifampicin
rpoC 763217 c.-153G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.91 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.91 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 0.91 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 0.91 rifampicin
rpoC 763414 c.45T>C synonymous_variant 0.91 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 0.91 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 0.93 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 0.93 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 0.94 rifampicin
rpoC 763456 c.87A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>T synonymous_variant 0.95 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.97 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.98 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>T synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763747 c.378G>A synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763837 c.468G>C synonymous_variant 1.0 rifampicin
rpoC 763840 c.471G>C synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763861 c.492C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763882 c.513G>A synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 1.0 rifampicin
rpoC 763924 c.555G>A synonymous_variant 1.0 rifampicin
rpoC 763930 c.561G>A synonymous_variant 1.0 rifampicin
rpoC 763933 c.564C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763947 p.Ala193Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764207 p.Val280Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 0.96 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764353 c.984G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764707 c.1338G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 1.0 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.88 rifampicin
rpoC 765016 c.1647C>A synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.88 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.83 rifampicin
rpoC 765383 c.2014_2016delATGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 0.95 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 0.95 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.96 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.96 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.96 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 0.93 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.91 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 0.88 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 0.87 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.83 rifampicin
rpoC 765533 p.Tyr722His missense_variant 0.79 rifampicin Uncertain significance
rpoC 765544 c.2175C>T synonymous_variant 0.91 rifampicin
rpoC 765547 c.2178C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.91 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.91 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.91 rifampicin
rpoC 765577 c.2208G>T synonymous_variant 0.91 rifampicin
rpoC 765751 c.2382C>G synonymous_variant 0.9 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.9 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.94 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 0.94 rifampicin
rpoC 765779 c.2410_2412delGACinsAG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.95 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.95 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.95 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.96 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 0.96 rifampicin
rpoC 765814 c.2445A>C synonymous_variant 0.96 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.96 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 1.0 rifampicin
rpoC 765874 c.2505G>C synonymous_variant 1.0 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765997 c.2628T>C synonymous_variant 1.0 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766027 c.2658G>T synonymous_variant 1.0 rifampicin
rpoC 766034 p.His889Thr missense_variant 1.0 rifampicin
rpoC 766042 c.2673C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766428 c.3059_3060insTAC disruptive_inframe_insertion 1.0 rifampicin
rpoC 766433 c.3065delA frameshift_variant 1.0 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 1.0 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>T synonymous_variant 1.0 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 1.0 rifampicin
rpoC 766493 p.Gly1042Asn missense_variant 1.0 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 1.0 rifampicin
rpoC 766517 c.3148_3150delACCinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766534 c.3165C>G synonymous_variant 1.0 rifampicin
rpoC 766539 c.3171_3174delCGGC frameshift_variant 1.0 rifampicin
rpoC 766548 c.3179_3180insACAA frameshift_variant 1.0 rifampicin
rpoC 766554 p.Tyr1062Phe missense_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766579 c.3210C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>T synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 1.0 rifampicin
rpoC 766658 c.3289_3291delCGGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766694 c.3325_3327delCAGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766981 c.3612T>C synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 1.0 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 1.0 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.83 rifampicin
mmpL5 775826 c.2655G>C synonymous_variant 0.82 clofazimine
bedaquiline
mmpL5 775829 c.2652C>G synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775834 p.Ala883Ser missense_variant 0.81 clofazimine
bedaquiline
mmpL5 775838 c.2643G>C synonymous_variant 0.81 clofazimine
bedaquiline
mmpL5 775847 c.2634G>T synonymous_variant 0.98 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 0.85 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775865 c.2616T>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775877 c.2604C>A synonymous_variant 0.74 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsTG frameshift_variant&missense_variant 0.81 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775892 c.2589C>T synonymous_variant 0.83 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.86 clofazimine
bedaquiline
mmpL5 775915 p.Ala856Ser missense_variant 0.86 clofazimine
bedaquiline
mmpL5 775916 c.2565T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.57 clofazimine
bedaquiline
mmpL5 775922 c.2557_2559delCTGinsTA frameshift_variant&synonymous_variant 0.3 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775951 c.2530C>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.76 clofazimine
bedaquiline
mmpL5 775970 c.2511G>C synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775994 c.2485_2487delATCinsCG frameshift_variant&missense_variant 0.96 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775997 c.2484T>G synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776005 p.Ile826Leu missense_variant 0.96 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776075 c.2406C>G synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781595 c.36T>C synonymous_variant 0.95 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.95 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.95 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.95 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.9 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 0.91 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.97 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.97 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.95 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.96 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.97 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.95 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 0.94 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 0.94 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 0.95 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.95 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.96 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.99 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.99 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.99 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.99 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.99 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.98 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.99 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.99 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.99 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.99 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.99 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781901 c.342C>T synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.96 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.97 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.97 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.97 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.97 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.97 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 0.97 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.97 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.97 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.98 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.98 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.98 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.96 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.96 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.96 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.93 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.93 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.93 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.93 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.93 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.93 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.92 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.91 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.9 linezolid
rplC 801195 c.387G>T synonymous_variant 0.92 linezolid
rplC 801205 p.Arg133Ala missense_variant 1.0 linezolid
rplC 801210 c.402T>C synonymous_variant 1.0 linezolid
rplC 801220 p.Ser138Ala missense_variant 1.0 linezolid
rplC 801231 c.423C>T synonymous_variant 0.93 linezolid
rplC 801237 c.429G>A synonymous_variant 0.94 linezolid
rplC 801252 c.444G>C synonymous_variant 0.93 linezolid
rplC 801264 c.456C>T synonymous_variant 0.93 linezolid
rplC 801267 c.459A>C synonymous_variant 0.92 linezolid
rplC 801276 c.468G>C synonymous_variant 0.93 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.86 linezolid
rplC 801285 c.477G>C synonymous_variant 0.86 linezolid
rplC 801307 c.499_501delGCCinsTG frameshift_variant&missense_variant 0.83 linezolid
rplC 801312 c.504G>C synonymous_variant 0.82 linezolid
rplC 801315 c.507G>T synonymous_variant 0.82 linezolid
fbiC 1304559 p.Glu543Asp missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.94 pyrazinamide
sigE 1364751 c.339C>G synonymous_variant 0.94 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.92 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.92 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 0.92 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 0.92 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.93 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.93 pyrazinamide
sigE 1364796 c.384G>A synonymous_variant 0.94 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.94 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.94 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.95 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 0.96 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.96 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.96 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.96 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.96 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.96 pyrazinamide
sigE 1364871 c.459C>T synonymous_variant 0.96 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364898 c.486C>T synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364931 c.519C>T synonymous_variant 1.0 pyrazinamide
sigE 1364950 c.538_540delGCAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1364962 c.550_552delCCTinsGC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1364992 p.Pro194Ala missense_variant 1.0 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 1.0 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 1.0 pyrazinamide
sigE 1365048 c.636G>A synonymous_variant 1.0 pyrazinamide
sigE 1365051 c.639G>A synonymous_variant 1.0 pyrazinamide
sigE 1365063 c.651A>G synonymous_variant 1.0 pyrazinamide
sigE 1365069 c.657C>T synonymous_variant 1.0 pyrazinamide
sigE 1365075 c.663G>A synonymous_variant 1.0 pyrazinamide
sigE 1365081 c.669G>T synonymous_variant 1.0 pyrazinamide
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 1.0 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 1.0 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 1.0 bedaquiline
atpE 1461227 c.183G>A synonymous_variant 1.0 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 1.0 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474102 n.446_449delAGTA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474108 n.451C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474110 n.453_454insCGGTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631_632delCCinsTCGACT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474292 n.635T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474417 n.761_767delCACGCGC non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474430 n.773delCinsTAG non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474432 n.775C>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474434 n.777_778insTG non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475353 n.1696A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475354 n.1697A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475382 n.1725A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475395 n.1738T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475615 n.1958C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475618 n.1961C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475626 n.1969delTinsCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475629 n.1972G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673877 c.-325C>G upstream_gene_variant 0.75 ethionamide
isoniazid
inhA 1673886 c.-316C>T upstream_gene_variant 0.78 ethionamide
isoniazid
inhA 1673895 c.-307C>T upstream_gene_variant 0.81 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.81 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.81 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.85 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1673931 c.-271C>G upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673941 c.502_504delGCCinsTG frameshift_variant&missense_variant 0.84 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.84 ethionamide
isoniazid
fabG1 1673962 p.Asn175Gly missense_variant 0.84 ethionamide
isoniazid
inhA 1673967 c.-235G>C upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673973 c.-229G>C upstream_gene_variant 0.85 ethionamide
isoniazid Uncertain significance
inhA 1673976 c.-226T>C upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.94 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.71 ethionamide
isoniazid
fabG1 1674083 p.Ala215Glu missense_variant 0.71 ethionamide
isoniazid
inhA 1674096 c.-106G>C upstream_gene_variant 0.71 ethionamide
isoniazid
fabG1 1674098 p.Val220Ala missense_variant 0.71 ethionamide
isoniazid
inhA 1674102 c.-100C>G upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1674114 c.-88T>A upstream_gene_variant 0.71 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674123 c.-79T>C upstream_gene_variant 0.73 ethionamide
isoniazid
rpsA 1833547 c.6G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 0.98 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1833709 c.168C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.96 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.98 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.98 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.99 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834168 c.627C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.98 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.97 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.93 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.92 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.92 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.92 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.9 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.9 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.9 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.9 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834829 c.1288_1290delGCGinsAC frameshift_variant&missense_variant 0.92 pyrazinamide Uncertain significance
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.97 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.97 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.97 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.96 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.96 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 0.93 linezolid
katG 2155668 c.444G>C synonymous_variant 0.7 isoniazid
katG 2155674 c.438G>C synonymous_variant 0.8 isoniazid
katG 2155680 c.432G>A synonymous_variant 0.8 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.8 isoniazid
katG 2155696 p.Ala139Val missense_variant 0.79 isoniazid
katG 2155716 c.396T>G synonymous_variant 0.81 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.8 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.8 isoniazid
katG 2155742 p.Gly124Arg missense_variant 0.73 isoniazid
katG 2155747 p.Ala122Gly missense_variant 0.73 isoniazid
katG 2155752 c.360C>T synonymous_variant 0.71 isoniazid
katG 2155769 p.Ile115Val missense_variant 0.77 isoniazid
katG 2155770 c.342C>G synonymous_variant 0.77 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Phe missense_variant 1.0 isoniazid
kasA 2518726 c.612G>A synonymous_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.96 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.96 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.96 isoniazid
kasA 2518787 c.673_675delCGGinsGT frameshift_variant&missense_variant 0.96 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.96 isoniazid
kasA 2518795 c.681C>T synonymous_variant 0.96 isoniazid
kasA 2518813 c.699C>T synonymous_variant 0.97 isoniazid
kasA 2518816 c.702C>T synonymous_variant 0.97 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.96 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.96 isoniazid
kasA 2518847 p.Leu245Met missense_variant 0.96 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 0.96 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.96 isoniazid
kasA 2518877 p.Lys255Leu missense_variant 0.95 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.92 isoniazid
kasA 2518903 c.789C>T synonymous_variant 0.92 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.9 isoniazid
kasA 2518907 c.793T>C synonymous_variant 0.9 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.9 isoniazid
Rv2477c 2783344 c.699C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.75 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783456 p.Gln196Leu missense_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996350 c.-389C>G upstream_gene_variant 0.8 capreomycin
Rv2681 2996354 c.-385C>T upstream_gene_variant 0.8 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 0.9 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 0.91 capreomycin
Rv2681 2996440 c.-299G>C upstream_gene_variant 0.86 capreomycin
Rv2681 2996443 c.-296T>C upstream_gene_variant 0.86 capreomycin
Rv2680 2996446 c.342A>G synonymous_variant 0.86 capreomycin Not assoc w R - Interim
Rv2681 2996449 c.-290C>T upstream_gene_variant 0.86 capreomycin
Rv2681 2996458 c.-281C>A upstream_gene_variant 0.86 capreomycin
Rv2681 2996461 c.-278G>C upstream_gene_variant 0.92 capreomycin
Rv2752c 3065022 c.1170G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065058 c.1134C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065061 c.1131C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065082 c.1110G>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065109 c.1081_1083delAGAinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065126 p.Ser356Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1062A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065146 p.Phe349Tyr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065154 c.1038G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065160 c.1032C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065166 c.1026C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065174 c.1018C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065181 c.1011G>C synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065187 c.1003_1005delGTGinsAC frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065196 c.996T>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065210 c.982T>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065229 c.963G>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065235 c.957G>A synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065249 c.943T>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065250 c.942G>A synonymous_variant 0.91 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065255 p.Ser313Ala missense_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyA 3073905 c.567C>T synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073926 c.546G>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.87 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073962 c.510G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073971 c.501C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073993 c.478_479delAGinsTC synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074013 c.459C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074046 c.426G>A synonymous_variant 1.0 para-aminosalicylic_acid
lpqB 3623428 c.1483T>C synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3623429 c.1482G>A synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3623437 c.1471_1473delTCG conservative_inframe_deletion 0.83 bedaquiline
rifampicin
lpqB 3623444 c.1466_1467insCAA disruptive_inframe_insertion 0.83 bedaquiline
rifampicin
lpqB 3623459 c.1452G>C synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3623462 c.1449G>T synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623471 c.1440C>T synonymous_variant 0.83 bedaquiline
rifampicin
lpqB 3624617 c.294C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624636 p.His92Arg missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3624643 p.Ile90Leu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624650 c.261G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624656 c.255C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624673 p.Ala80Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624675 p.Asn79Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624680 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624704 c.207G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624719 c.192C>T synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625243 c.-333T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625252 c.1362G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625255 c.-345T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625258 c.-348G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625264 c.1350C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625300 c.-390C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625312 c.-402G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625325 p.His430Arg missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625330 c.-420C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625336 c.-426C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625711 c.903C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625720 c.894G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625732 c.882C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625753 p.Ala287Gln missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625804 c.808_810delAGGinsCC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625822 c.-912C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625828 c.-918G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626753 c.-140G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626792 c.-179G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626795 c.-182C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626798 c.-185T>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>T upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626857 c.-244T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626864 c.484_486delTTGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626894 c.-281C>T upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626933 c.-320C>T upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626939 c.411A>G synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626942 c.-329A>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626949 p.Ala134Asn missense_variant 0.9 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrA 3626962 p.Met130Leu missense_variant 0.9 bedaquiline
rifampicin
mtrA 3626969 c.381C>T synonymous_variant 0.91 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626972 c.-359A>G upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.94 bedaquiline
rifampicin Uncertain significance
mtrB 3626999 c.-386G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627002 c.-389G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627032 c.-419G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.97 bedaquiline
rifampicin
mtrB 3627044 c.-431C>T upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3627062 c.-449G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrB 3627083 c.-470G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrA 3627137 c.211_213delTTGinsCC frameshift_variant&missense_variant 0.86 bedaquiline
rifampicin
mtrB 3627158 c.-545C>G upstream_gene_variant 0.85 bedaquiline
rifampicin
rpoA 3877545 c.963G>C synonymous_variant 0.9 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 0.9 rifampicin
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 0.9 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.96 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877638 c.870T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.94 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.92 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.91 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 0.91 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 0.89 rifampicin
rpoA 3877731 c.777G>T synonymous_variant 0.88 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.88 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.88 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>A synonymous_variant 0.96 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877875 c.633T>A synonymous_variant 1.0 rifampicin
rpoA 3877878 c.630G>C synonymous_variant 1.0 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 1.0 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.98 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>C synonymous_variant 1.0 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>G synonymous_variant 0.97 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.97 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.97 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.97 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.97 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.97 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>G synonymous_variant 0.97 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.97 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.98 rifampicin
rpoA 3878061 c.447G>A synonymous_variant 0.96 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.97 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.97 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.97 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.96 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.96 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.97 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.97 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>A synonymous_variant 0.97 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.97 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878238 c.270C>T synonymous_variant 0.97 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 0.97 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.97 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.97 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.98 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.97 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>A synonymous_variant 0.95 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.95 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878415 c.93C>T synonymous_variant 1.0 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878450 p.Gln20Lys missense_variant 1.0 rifampicin
rpoA 3878454 c.54A>C synonymous_variant 1.0 rifampicin
clpC1 4038519 p.Arg729Gln missense_variant 0.83 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.83 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.79 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.79 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.85 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.9 pyrazinamide
clpC1 4038584 c.2121G>A synonymous_variant 0.93 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.93 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.96 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.95 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.94 pyrazinamide
clpC1 4038660 c.2044_2045delTCinsAG synonymous_variant 0.94 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038679 p.Pro676Ala missense_variant 0.95 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038767 c.1938G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038770 c.1935C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038776 c.1929G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038905 c.1800A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039046 c.1659C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.98 pyrazinamide
clpC1 4039100 c.1605C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4039103 c.1602T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039118 c.1587C>A synonymous_variant 0.98 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039320 p.Ala462Gly missense_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039361 c.1344C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039457 c.1248C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039478 c.1227G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039541 c.1164C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039574 p.Ala377Gly missense_variant 0.98 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.98 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.98 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039883 c.822G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040003 c.702G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.97 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040126 c.579C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040309 c.396C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040375 c.330G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040411 c.294T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.97 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.97 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040468 c.237G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040480 c.225T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040495 c.210C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.95 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.93 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.93 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.93 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.93 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.93 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040618 c.87C>G synonymous_variant 0.91 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.86 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.86 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.81 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
panD 4044177 c.105C>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
panD 4044180 p.Asp34Glu missense_variant 0.92 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.92 pyrazinamide
panD 4044189 c.93C>T synonymous_variant 0.92 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.92 pyrazinamide
panD 4044210 c.72C>T synonymous_variant 0.92 pyrazinamide
panD 4044213 c.69C>G synonymous_variant 0.92 pyrazinamide
glpK 4138523 c.1233C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138526 p.Asp410Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138565 c.1191G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138571 c.1185C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138583 c.1173G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138586 c.1170C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138592 c.1164C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138643 c.1113A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138661 c.1095T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138727 c.1029C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138747 c.1009C>T synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138763 c.993G>A synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138769 c.987G>A synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138778 c.978C>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138781 c.975G>T synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240768 c.906G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240786 c.924C>T synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 1.0 ethambutol
embC 4240828 c.966G>A synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.9 ethambutol
embC 4241074 c.1212G>C synonymous_variant 0.88 ethambutol
embC 4241095 c.1233C>T synonymous_variant 0.93 ethambutol
embC 4241104 c.1242G>A synonymous_variant 0.88 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 0.87 ethambutol
embC 4241109 p.Ala416Gly missense_variant 0.87 ethambutol
embC 4241121 p.Ser420Asn missense_variant 0.86 ethambutol
embB 4247449 c.936C>T synonymous_variant 0.9 ethambutol
embB 4247455 c.942C>T synonymous_variant 0.9 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.93 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.94 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.96 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.95 ethambutol
embB 4247511 p.Tyr333Phe missense_variant 0.96 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.95 ethambutol
embB 4247536 c.1023C>A synonymous_variant 0.95 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.93 ethambutol
embB 4247555 c.1042_1044delCTGinsAC frameshift_variant&missense_variant 0.93 ethambutol
embB 4247566 c.1053C>A synonymous_variant 0.93 ethambutol
embB 4247572 c.1059A>C synonymous_variant 1.0 ethambutol
embB 4247579 p.Ala356Ile missense_variant 1.0 ethambutol
embB 4247582 p.Ala357Cys missense_variant 1.0 ethambutol
embB 4247586 p.Gly358Ala missense_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248097 c.1584C>G synonymous_variant 0.93 ethambutol
embB 4248112 c.1599C>G synonymous_variant 0.94 ethambutol
embB 4248118 c.1605T>C synonymous_variant 0.93 ethambutol
embB 4248121 c.1608G>C synonymous_variant 0.93 ethambutol
embB 4248124 c.1611G>T synonymous_variant 0.93 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.93 ethambutol
embB 4248133 c.1620C>G synonymous_variant 0.93 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.9 ethambutol
embB 4248143 c.1630_1632delTTGinsAC frameshift_variant&missense_variant 0.9 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.94 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.93 ethambutol
embB 4248167 p.Thr552Ala missense_variant 0.94 ethambutol
embB 4248170 c.1657_1659delGCGinsTC frameshift_variant&missense_variant 0.94 ethambutol
embB 4248173 p.Val554Leu missense_variant 0.94 ethambutol
embB 4248199 c.1686A>G synonymous_variant 0.98 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.98 ethambutol
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 0.97 ethambutol
embB 4248220 c.1707A>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4248225 p.Ala571Val missense_variant 0.97 ethambutol Uncertain significance
embB 4248233 c.1720C>T synonymous_variant 0.89 ethambutol
embB 4248242 p.Val577Ile missense_variant 0.89 ethambutol
embB 4248252 p.Gly580Ala missense_variant 0.85 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.85 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.85 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.88 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.82 ethambutol