TB-Profiler

TB-Profiler result

Run: ERR4769521

This average coverage of the target regions is below the recommended 30x. Some mutations may not be detected due to low coverage.

Summary

Run ID: ERR4769521

Sample name:

Date: 2024-04-16T09:49:55.071572

Number of reads: 601911

Percentage reads mapped: 15.86

Median coverage: 3.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: RR-TB

Download CSV Download TXT Download JSON

Lineage Table: The lineage is inferred by analysing lineage specific SNPs

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	0.94
lineage4.9	Euro-American (H37Rv-like)	None	0.94

Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin	rpoB	c.1327_1329delTTGinsCC	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
isoniazid
ethambutol	embB	p.Asp311Gly		Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid	fgd1	c.166_168delTCCinsGG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
delamanid	fgd1	c.202_204delCTGinsAC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.205_207delCTGinsGC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.730_732delAACinsGG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	c.1132_1134delGCGinsTC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	c.1135_1137delGCGinsAC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.1189_1191delAAAinsCG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
bedaquiline
linezolid

Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
fgd1	490948	c.166_168delTCCinsGG	frameshift_variant&missense_variant	0.94	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490948	c.166_168delTCCinsGG	frameshift_variant&missense_variant	0.94	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490984	c.202_204delCTGinsAC	frameshift_variant&missense_variant	0.98	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490984	c.202_204delCTGinsAC	frameshift_variant&missense_variant	0.98	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490987	c.205_207delCTGinsGC	frameshift_variant&missense_variant	0.98	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490987	c.205_207delCTGinsGC	frameshift_variant&missense_variant	0.98	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491083	c.301_303delGTTinsAC	frameshift_variant&missense_variant	0.97	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491083	c.301_303delGTTinsAC	frameshift_variant&missense_variant	0.97	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491512	c.730_732delAACinsGG	frameshift_variant&missense_variant	0.79	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491512	c.730_732delAACinsGG	frameshift_variant&missense_variant	0.79	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
rpoB	761133	c.1327_1329delTTGinsCC	frameshift_variant&missense_variant	1.0	rifampicin	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
fbiC	1304062	c.1132_1134delGCGinsTC	frameshift_variant&missense_variant	1.0	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304062	c.1132_1134delGCGinsTC	frameshift_variant&missense_variant	1.0	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304065	c.1135_1137delGCGinsAC	frameshift_variant&missense_variant	1.0	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304065	c.1135_1137delGCGinsAC	frameshift_variant&missense_variant	1.0	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304119	c.1189_1191delAAAinsCG	frameshift_variant&missense_variant	1.0	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304119	c.1189_1191delAAAinsCG	frameshift_variant&missense_variant	1.0	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
embB	4247445	p.Asp311Gly	missense_variant	0.9	ethambutol		Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
dnaA	660	c.660G>C	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
dnaA	663	c.663A>G	synonymous_variant	0.9	isoniazid	Not assoc w R - Interim
dnaA	672	c.672T>C	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
dnaA	678	c.678A>G	synonymous_variant	0.93	isoniazid	Not assoc w R - Interim
dnaA	690	c.690G>C	synonymous_variant	0.91	isoniazid
dnaA	693	c.693A>G	synonymous_variant	0.94	isoniazid	Not assoc w R - Interim
dnaA	705	c.705A>G	synonymous_variant	0.94	isoniazid
dnaA	708	c.708T>C	synonymous_variant	0.94	isoniazid
dnaA	714	c.714C>G	synonymous_variant	0.94	isoniazid	Not assoc w R - Interim
dnaA	741	c.741T>C	synonymous_variant	0.93	isoniazid	Not assoc w R - Interim
dnaA	744	c.744C>T	synonymous_variant	0.93	isoniazid
dnaA	747	c.747G>C	synonymous_variant	0.94	isoniazid
dnaA	750	c.750C>G	synonymous_variant	0.94	isoniazid
dnaA	756	c.756T>C	synonymous_variant	0.93	isoniazid
dnaA	767	p.Val256Ala	missense_variant	0.92	isoniazid
dnaA	769	c.769_771delGCAinsTC	frameshift_variant&missense_variant	0.91	isoniazid	Uncertain significance
dnaA	777	c.777A>G	synonymous_variant	0.93	isoniazid
dnaA	793	c.793_795delGTAinsAC	frameshift_variant&missense_variant	0.91	isoniazid	Uncertain significance
dnaA	805	c.805T>C	synonymous_variant	0.93	isoniazid
dnaA	822	c.822A>G	synonymous_variant	0.92	isoniazid
dnaA	828	c.828T>C	synonymous_variant	0.91	isoniazid	Not assoc w R - Interim
dnaA	831	c.831A>G	synonymous_variant	0.91	isoniazid
dnaA	837	c.837A>G	synonymous_variant	0.91	isoniazid
dnaA	840	c.840G>A	synonymous_variant	0.91	isoniazid
dnaA	843	c.843T>C	synonymous_variant	0.91	isoniazid	Not assoc w R - Interim
dnaA	846	c.846T>C	synonymous_variant	0.89	isoniazid
dnaA	849	c.849A>G	synonymous_variant	0.91	isoniazid
dnaA	852	c.852G>A	synonymous_variant	0.91	isoniazid	Not assoc w R - Interim
dnaA	877	c.877T>C	synonymous_variant	0.96	isoniazid
dnaA	885	c.885T>C	synonymous_variant	0.96	isoniazid
dnaA	897	c.897A>G	synonymous_variant	0.96	isoniazid
dnaA	909	c.909A>C	synonymous_variant	0.98	isoniazid	Not assoc w R - Interim
dnaA	912	c.912T>C	synonymous_variant	0.98	isoniazid
dnaA	918	c.918C>G	synonymous_variant	1.0	isoniazid
dnaA	921	c.921A>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	927	c.927G>A	synonymous_variant	1.0	isoniazid
dnaA	933	c.933C>G	synonymous_variant	1.0	isoniazid
dnaA	955	c.955_957delAGAinsCG	frameshift_variant&synonymous_variant	1.0	isoniazid	Uncertain significance
dnaA	963	c.963C>G	synonymous_variant	1.0	isoniazid
dnaA	966	c.966T>C	synonymous_variant	1.0	isoniazid
dnaA	975	c.975G>C	synonymous_variant	1.0	isoniazid
dnaA	976	c.976C>T	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
dnaA	984	c.984T>C	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
dnaA	990	c.990A>C	synonymous_variant	0.97	isoniazid
dnaA	993	c.993A>G	synonymous_variant	0.97	isoniazid
dnaA	996	c.996A>G	synonymous_variant	0.97	isoniazid
dnaA	1002	c.1002G>A	synonymous_variant	0.97	isoniazid
dnaA	1014	c.1014C>G	synonymous_variant	0.97	isoniazid
dnaA	1020	c.1020C>G	synonymous_variant	0.97	isoniazid
dnaA	1024	c.1024T>C	synonymous_variant	0.96	isoniazid
dnaA	1035	c.1035A>G	synonymous_variant	0.95	isoniazid
dnaA	1038	c.1038A>G	synonymous_variant	0.94	isoniazid
dnaA	1047	p.Glu349Asp	missense_variant	0.9	isoniazid
dnaA	1068	c.1068T>C	synonymous_variant	0.9	isoniazid
dnaA	1071	c.1071C>G	synonymous_variant	0.9	isoniazid
dnaA	1077	c.1077A>G	synonymous_variant	0.9	isoniazid
dnaA	1092	c.1092T>C	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
dnaA	1098	c.1098A>G	synonymous_variant	0.95	isoniazid
dnaA	1104	c.1104T>C	synonymous_variant	0.95	isoniazid
dnaA	1110	c.1110T>C	synonymous_variant	0.96	isoniazid
dnaA	1113	c.1113A>G	synonymous_variant	0.96	isoniazid
dnaA	1128	c.1128G>C	synonymous_variant	0.98	isoniazid
dnaA	1152	c.1152A>G	synonymous_variant	1.0	isoniazid
dnaA	1153	c.1153T>C	synonymous_variant	1.0	isoniazid
dnaA	1161	c.1161A>G	synonymous_variant	1.0	isoniazid
dnaA	1164	c.1164A>C	synonymous_variant	1.0	isoniazid
dnaA	1167	c.1167A>G	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	1173	c.1174_1177delAAAG	frameshift_variant	1.0	isoniazid	Uncertain significance
dnaA	1179	c.1179_1180insGTCA	frameshift_variant	1.0	isoniazid	Uncertain significance
dnaA	1191	c.1191T>C	synonymous_variant	0.98	isoniazid
dnaA	1194	c.1194G>C	synonymous_variant	0.98	isoniazid
dnaA	1197	c.1197T>G	synonymous_variant	0.98	isoniazid
dnaA	1203	c.1203T>C	synonymous_variant	0.98	isoniazid
dnaA	1210	p.Ala404Ser	missense_variant	0.98	isoniazid
dnaA	1215	c.1215C>T	synonymous_variant	0.95	isoniazid
dnaA	1220	p.Asn407Ser	missense_variant	0.95	isoniazid
dnaA	1230	c.1230A>G	synonymous_variant	0.96	isoniazid
dnaA	1242	c.1242G>C	synonymous_variant	0.95	isoniazid
dnaA	1243	p.Thr415Ala	missense_variant	0.95	isoniazid	Uncertain significance
dnaA	1254	c.1254T>C	synonymous_variant	0.93	isoniazid
dnaA	1266	c.1266A>G	synonymous_variant	0.91	isoniazid
gyrB	6178	c.939C>T	synonymous_variant	0.97	levofloxacin
gyrB	6178	c.939C>T	synonymous_variant	0.97	moxifloxacin
gyrB	6190	c.951A>G	synonymous_variant	0.97	levofloxacin
gyrB	6190	c.951A>G	synonymous_variant	0.97	moxifloxacin
gyrB	6203	p.Ser322Ala	missense_variant	0.97	levofloxacin
gyrB	6203	p.Ser322Ala	missense_variant	0.97	moxifloxacin
gyrB	6208	c.969G>A	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6208	c.969G>A	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6214	c.975G>C	synonymous_variant	0.97	levofloxacin
gyrB	6214	c.975G>C	synonymous_variant	0.97	moxifloxacin
gyrB	6215	c.976_978delTCGinsAGC	synonymous_variant	0.97	levofloxacin
gyrB	6215	c.976_978delTCGinsAGC	synonymous_variant	0.97	moxifloxacin
gyrB	6223	c.984G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6223	c.984G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6242	p.Arg335Lys	missense_variant	0.98	levofloxacin
gyrB	6242	p.Arg335Lys	missense_variant	0.98	moxifloxacin
gyrB	6250	c.1011A>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6250	c.1011A>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6253	c.1014G>C	synonymous_variant	0.98	levofloxacin
gyrB	6253	c.1014G>C	synonymous_variant	0.98	moxifloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.97	levofloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.97	moxifloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.98	levofloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.98	moxifloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.98	levofloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.98	moxifloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.98	levofloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.98	moxifloxacin
gyrB	6307	c.1068T>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6307	c.1068T>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	6310	c.-992G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6310	c.-992G>C	upstream_gene_variant	0.98	moxifloxacin
gyrB	6319	c.1080G>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6319	c.1080G>C	synonymous_variant	0.97	moxifloxacin
gyrA	6325	c.-977C>G	upstream_gene_variant	0.95	levofloxacin
gyrA	6325	c.-977C>G	upstream_gene_variant	0.95	moxifloxacin
gyrB	6326	p.Ser363Ala	missense_variant	0.97	levofloxacin
gyrB	6326	p.Ser363Ala	missense_variant	0.97	moxifloxacin
gyrB	6346	c.1107C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6346	c.1107C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6362	c.1123_1125delTTGinsCC	frameshift_variant&missense_variant	1.0	levofloxacin	Uncertain significance
gyrB	6362	c.1123_1125delTTGinsCC	frameshift_variant&missense_variant	1.0	moxifloxacin
gyrA	6379	c.-923C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6379	c.-923C>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6397	c.1158G>A	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6397	c.1158G>A	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6398	p.Val387Ile	missense_variant	1.0	levofloxacin
gyrB	6398	p.Val387Ile	missense_variant	1.0	moxifloxacin
gyrA	6403	c.-899T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6403	c.-899T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6416	p.Thr393Gly	missense_variant	1.0	levofloxacin
gyrB	6416	p.Thr393Gly	missense_variant	1.0	moxifloxacin
gyrA	6427	c.-875T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6427	c.-875T>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6430	c.-872A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6430	c.-872A>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6440	p.Thr401Ala	missense_variant	1.0	levofloxacin
gyrB	6440	p.Thr401Ala	missense_variant	1.0	moxifloxacin
gyrB	6445	p.Asp402Glu	missense_variant	1.0	levofloxacin	Uncertain significance
gyrB	6445	p.Asp402Glu	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrB	6452	p.Val405Thr	missense_variant	1.0	levofloxacin
gyrB	6452	p.Val405Thr	missense_variant	1.0	moxifloxacin
gyrA	6469	c.-833T>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6469	c.-833T>G	upstream_gene_variant	0.98	moxifloxacin
gyrA	6472	c.-830G>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6472	c.-830G>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6475	c.-827C>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6475	c.-827C>G	upstream_gene_variant	0.98	moxifloxacin
gyrA	6478	c.-824G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6478	c.-824G>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6484	c.-818A>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6484	c.-818A>G	upstream_gene_variant	0.98	moxifloxacin
gyrB	6487	c.1248C>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6487	c.1248C>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	6490	c.-812T>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6490	c.-812T>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6496	c.-806G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6496	c.-806G>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6499	c.-803A>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6499	c.-803A>G	upstream_gene_variant	0.98	moxifloxacin
gyrA	6508	c.-794A>G	upstream_gene_variant	0.95	levofloxacin
gyrA	6508	c.-794A>G	upstream_gene_variant	0.95	moxifloxacin
gyrA	6511	c.-791A>T	upstream_gene_variant	0.95	levofloxacin
gyrA	6511	c.-791A>T	upstream_gene_variant	0.95	moxifloxacin
gyrA	6523	c.-779G>T	upstream_gene_variant	0.96	levofloxacin
gyrA	6523	c.-779G>T	upstream_gene_variant	0.96	moxifloxacin
gyrA	6547	c.-755T>C	upstream_gene_variant	0.95	levofloxacin
gyrA	6547	c.-755T>C	upstream_gene_variant	0.95	moxifloxacin
gyrA	6550	c.-752A>C	upstream_gene_variant	0.95	levofloxacin
gyrA	6550	c.-752A>C	upstream_gene_variant	0.95	moxifloxacin
gyrB	6551	c.1312T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrB	6551	c.1312T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	6571	c.-731T>C	upstream_gene_variant	0.94	levofloxacin
gyrA	6571	c.-731T>C	upstream_gene_variant	0.94	moxifloxacin
gyrB	6577	c.1338T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrB	6577	c.1338T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	6583	c.-719G>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6583	c.-719G>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6604	c.-698G>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6604	c.-698G>C	upstream_gene_variant	0.93	moxifloxacin
gyrB	6608	p.Val457Ile	missense_variant	0.93	levofloxacin
gyrB	6608	p.Val457Ile	missense_variant	0.93	moxifloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6619	c.-683T>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6619	c.-683T>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	0.93	levofloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	0.93	moxifloxacin
gyrA	6628	c.-674C>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6628	c.-674C>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.94	levofloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.94	moxifloxacin
gyrA	6649	c.-653T>G	upstream_gene_variant	0.94	levofloxacin
gyrA	6649	c.-653T>G	upstream_gene_variant	0.94	moxifloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	0.97	moxifloxacin
gyrB	6680	c.1441C>T	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6680	c.1441C>T	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	6700	c.-602T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6700	c.-602T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	0.97	moxifloxacin
gyrA	6712	c.-590G>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6712	c.-590G>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6730	c.-572A>G	upstream_gene_variant	0.96	levofloxacin
gyrA	6730	c.-572A>G	upstream_gene_variant	0.96	moxifloxacin
gyrA	6733	c.-569G>A	upstream_gene_variant	0.97	levofloxacin
gyrA	6733	c.-569G>A	upstream_gene_variant	0.97	moxifloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	0.97	moxifloxacin
gyrB	6745	c.1506T>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6745	c.1506T>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	6760	c.-542G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6763	c.-539G>A	upstream_gene_variant	0.98	levofloxacin
gyrA	6763	c.-539G>A	upstream_gene_variant	0.98	moxifloxacin
gyrA	6775	c.-527G>T	upstream_gene_variant	0.98	levofloxacin
gyrA	6775	c.-527G>T	upstream_gene_variant	0.98	moxifloxacin
gyrB	6793	c.1554T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6797	p.Gly520Ser	missense_variant	0.97	levofloxacin
gyrB	6797	p.Gly520Ser	missense_variant	0.97	moxifloxacin
gyrB	6811	c.1572C>T	synonymous_variant	0.96	levofloxacin
gyrB	6811	c.1572C>T	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrB	6824	c.1585C>T	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6824	c.1585C>T	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	6844	c.-458T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6844	c.-458T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	0.97	moxifloxacin
gyrB	6856	c.1617T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6856	c.1617T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6860	p.Ser541Ala	missense_variant	0.97	levofloxacin
gyrB	6860	p.Ser541Ala	missense_variant	0.97	moxifloxacin
gyrA	6869	c.-433T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6869	c.-433T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6872	c.-430T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6872	c.-430T>C	upstream_gene_variant	0.97	moxifloxacin
gyrB	6878	c.1639T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrB	6878	c.1639T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrB	6881	c.1642T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrB	6881	c.1642T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrB	6896	p.Arg553Lys	missense_variant	0.99	levofloxacin
gyrB	6896	p.Arg553Lys	missense_variant	0.99	moxifloxacin
gyrB	6919	c.1680T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6919	c.1680T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6922	c.1683G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6922	c.1683G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6924	p.Phe562Tyr	missense_variant	0.98	levofloxacin
gyrB	6924	p.Phe562Tyr	missense_variant	0.98	moxifloxacin
gyrB	6926	c.1687T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6926	c.1687T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6931	c.1692A>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6931	c.1692A>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	6940	c.-362G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6940	c.-362G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6949	c.-353A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6949	c.-353A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6955	c.-347G>A	upstream_gene_variant	1.0	levofloxacin
gyrA	6955	c.-347G>A	upstream_gene_variant	1.0	moxifloxacin
gyrA	6961	c.-341G>A	upstream_gene_variant	1.0	levofloxacin
gyrA	6961	c.-341G>A	upstream_gene_variant	1.0	moxifloxacin
gyrA	6967	c.-335T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6967	c.-335T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6970	p.Asp577Glu	missense_variant	1.0	levofloxacin
gyrB	6970	p.Asp577Glu	missense_variant	1.0	moxifloxacin
gyrA	6982	c.-320A>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6982	c.-320A>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6988	c.-314C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6988	c.-314C>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	7000	c.-302C>T	upstream_gene_variant	1.0	levofloxacin
gyrA	7000	c.-302C>T	upstream_gene_variant	1.0	moxifloxacin
gyrB	7005	p.Gly589Ala	missense_variant	0.95	levofloxacin
gyrB	7005	p.Gly589Ala	missense_variant	0.95	moxifloxacin
gyrA	7015	c.-287G>A	upstream_gene_variant	0.92	levofloxacin
gyrA	7015	c.-287G>A	upstream_gene_variant	0.92	moxifloxacin
gyrA	7021	c.-281G>C	upstream_gene_variant	0.92	levofloxacin
gyrA	7021	c.-281G>C	upstream_gene_variant	0.92	moxifloxacin
gyrA	7362	p.Glu21Gln	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7362	p.Glu21Gln	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7394	c.93T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7394	c.93T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.96	levofloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.96	moxifloxacin
gyrA	7451	c.150C>G	synonymous_variant	0.97	levofloxacin
gyrA	7451	c.150C>G	synonymous_variant	0.97	moxifloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.97	levofloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7472	c.171T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7472	c.171T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7475	c.174A>C	synonymous_variant	0.97	levofloxacin
gyrA	7475	c.174A>C	synonymous_variant	0.97	moxifloxacin
gyrA	7480	p.Phe60Tyr	missense_variant	0.97	levofloxacin
gyrA	7480	p.Phe60Tyr	missense_variant	0.97	moxifloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.97	levofloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7487	c.186C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7487	c.186C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	7490	c.189C>T	synonymous_variant	0.97	levofloxacin
gyrA	7490	c.189C>T	synonymous_variant	0.97	moxifloxacin
gyrA	7496	c.195C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7496	c.195C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	7499	c.198G>C	synonymous_variant	0.97	levofloxacin
gyrA	7499	c.198G>C	synonymous_variant	0.97	moxifloxacin
gyrA	7511	c.210C>T	synonymous_variant	0.98	levofloxacin
gyrA	7511	c.210C>T	synonymous_variant	0.98	moxifloxacin
gyrA	7514	c.213C>G	synonymous_variant	0.98	levofloxacin
gyrA	7514	c.213C>G	synonymous_variant	0.98	moxifloxacin
gyrA	7517	c.216G>A	synonymous_variant	0.98	levofloxacin
gyrA	7517	c.216G>A	synonymous_variant	0.98	moxifloxacin
gyrA	7526	c.225G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	7526	c.225G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	7529	c.228G>C	synonymous_variant	0.98	levofloxacin
gyrA	7529	c.228G>C	synonymous_variant	0.98	moxifloxacin
gyrA	7532	c.231T>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	7532	c.231T>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7568	c.267C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7568	c.267C>T	synonymous_variant	1.0	moxifloxacin
gyrA	7585	p.Ser95Thr	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7585	p.Ser95Thr	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7592	c.291G>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7592	c.291G>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7595	c.294C>G	synonymous_variant	0.99	levofloxacin
gyrA	7595	c.294C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7607	c.306C>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7607	c.306C>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7626	c.325C>T	synonymous_variant	0.99	levofloxacin
gyrA	7626	c.325C>T	synonymous_variant	0.99	moxifloxacin
gyrA	7631	c.330G>C	synonymous_variant	0.99	levofloxacin
gyrA	7631	c.330G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7637	c.336C>G	synonymous_variant	0.99	levofloxacin
gyrA	7637	c.336C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7658	c.357A>G	synonymous_variant	0.99	levofloxacin
gyrA	7658	c.357A>G	synonymous_variant	0.99	moxifloxacin
gyrA	7664	c.363T>C	synonymous_variant	0.99	levofloxacin
gyrA	7664	c.363T>C	synonymous_variant	0.99	moxifloxacin
gyrA	7670	c.369A>G	synonymous_variant	0.99	levofloxacin
gyrA	7670	c.369A>G	synonymous_variant	0.99	moxifloxacin
gyrA	7676	c.375G>C	synonymous_variant	0.99	levofloxacin
gyrA	7676	c.375G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7679	c.378G>C	synonymous_variant	0.99	levofloxacin
gyrA	7679	c.378G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7697	c.396C>G	synonymous_variant	0.99	levofloxacin
gyrA	7697	c.396C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7700	c.399G>A	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7700	c.399G>A	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7710	c.409T>C	synonymous_variant	0.99	levofloxacin
gyrA	7710	c.409T>C	synonymous_variant	0.99	moxifloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.99	levofloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.99	moxifloxacin
gyrA	7748	c.447A>C	synonymous_variant	0.99	levofloxacin
gyrA	7748	c.447A>C	synonymous_variant	0.99	moxifloxacin
gyrA	7758	p.Ile153Val	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	7758	p.Ile153Val	missense_variant	1.0	moxifloxacin
gyrA	7763	c.462T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7763	c.462T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7769	c.468C>T	synonymous_variant	1.0	levofloxacin
gyrA	7769	c.468C>T	synonymous_variant	1.0	moxifloxacin
gyrA	7784	c.483A>G	synonymous_variant	1.0	levofloxacin
gyrA	7784	c.483A>G	synonymous_variant	1.0	moxifloxacin
gyrA	7787	c.486G>A	synonymous_variant	1.0	levofloxacin
gyrA	7787	c.486G>A	synonymous_variant	1.0	moxifloxacin
gyrA	7799	c.498A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7799	c.498A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7802	c.501C>G	synonymous_variant	1.0	levofloxacin
gyrA	7802	c.501C>G	synonymous_variant	1.0	moxifloxacin
gyrA	7814	c.513C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7814	c.513C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7821	c.520C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7821	c.520C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7832	c.531G>C	synonymous_variant	1.0	levofloxacin
gyrA	7832	c.531G>C	synonymous_variant	1.0	moxifloxacin
gyrA	7835	c.534A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7835	c.534A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7841	c.540C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7841	c.540C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7859	c.558A>C	synonymous_variant	1.0	levofloxacin
gyrA	7859	c.558A>C	synonymous_variant	1.0	moxifloxacin
gyrA	7865	c.564T>C	synonymous_variant	1.0	levofloxacin
gyrA	7865	c.564T>C	synonymous_variant	1.0	moxifloxacin
gyrA	7886	c.585T>C	synonymous_variant	1.0	levofloxacin
gyrA	7886	c.585T>C	synonymous_variant	1.0	moxifloxacin
gyrA	7892	c.591G>C	synonymous_variant	1.0	levofloxacin
gyrA	7892	c.591G>C	synonymous_variant	1.0	moxifloxacin
gyrA	7898	p.Asp199Glu	missense_variant	1.0	levofloxacin
gyrA	7898	p.Asp199Glu	missense_variant	1.0	moxifloxacin
gyrA	8121	c.820T>C	synonymous_variant	0.93	levofloxacin
gyrA	8121	c.820T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8129	c.828T>C	synonymous_variant	0.96	levofloxacin
gyrA	8129	c.828T>C	synonymous_variant	0.96	moxifloxacin
gyrA	8156	c.855T>C	synonymous_variant	0.97	levofloxacin
gyrA	8156	c.855T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8168	c.867A>G	synonymous_variant	0.98	levofloxacin
gyrA	8168	c.867A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8177	c.876A>C	synonymous_variant	0.98	levofloxacin
gyrA	8177	c.876A>C	synonymous_variant	0.98	moxifloxacin
gyrA	8187	c.886_888delCTGinsAC	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8187	c.886_888delCTGinsAC	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8198	c.897T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8198	c.897T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8199	p.Ser300Ala	missense_variant	0.98	levofloxacin
gyrA	8199	p.Ser300Ala	missense_variant	0.98	moxifloxacin
gyrA	8207	c.906T>C	synonymous_variant	0.98	levofloxacin
gyrA	8207	c.906T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.98	levofloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.98	moxifloxacin
gyrA	8219	c.918T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8219	c.918T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8225	c.924T>C	synonymous_variant	0.99	levofloxacin
gyrA	8225	c.924T>C	synonymous_variant	0.99	moxifloxacin
gyrA	8234	c.933T>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8234	c.933T>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8235	c.934_936delTTAinsCG	frameshift_variant&missense_variant	0.99	levofloxacin
gyrA	8235	c.934_936delTTAinsCG	frameshift_variant&missense_variant	0.99	moxifloxacin
gyrA	8253	p.Ile318Leu	missense_variant	1.0	levofloxacin
gyrA	8253	p.Ile318Leu	missense_variant	1.0	moxifloxacin
gyrA	8258	c.957G>A	synonymous_variant	1.0	levofloxacin
gyrA	8258	c.957G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8264	c.963T>C	synonymous_variant	1.0	levofloxacin
gyrA	8264	c.963T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8267	c.966G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8267	c.966G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8283	c.982_984delATCinsCG	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8283	c.982_984delATCinsCG	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8288	c.987T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8288	c.987T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8324	c.1023T>C	synonymous_variant	0.99	levofloxacin
gyrA	8324	c.1023T>C	synonymous_variant	0.99	moxifloxacin
gyrA	8339	c.1038A>C	synonymous_variant	0.99	levofloxacin
gyrA	8339	c.1038A>C	synonymous_variant	0.99	moxifloxacin
gyrA	8357	c.1056G>C	synonymous_variant	0.99	levofloxacin
gyrA	8357	c.1056G>C	synonymous_variant	0.99	moxifloxacin
gyrA	8366	c.1065G>C	synonymous_variant	0.98	levofloxacin
gyrA	8366	c.1065G>C	synonymous_variant	0.98	moxifloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.98	levofloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.98	moxifloxacin
gyrA	8390	c.1089C>G	synonymous_variant	0.98	levofloxacin
gyrA	8390	c.1089C>G	synonymous_variant	0.98	moxifloxacin
gyrA	8391	c.1090_1092delTATinsCC	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8391	c.1090_1092delTATinsCC	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8399	c.1098T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8399	c.1098T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8402	c.1101C>T	synonymous_variant	0.98	levofloxacin
gyrA	8402	c.1101C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8405	c.1104C>T	synonymous_variant	0.98	levofloxacin
gyrA	8405	c.1104C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8408	c.1107A>G	synonymous_variant	0.98	levofloxacin
gyrA	8408	c.1107A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8417	c.1116C>G	synonymous_variant	0.96	levofloxacin
gyrA	8417	c.1116C>G	synonymous_variant	0.96	moxifloxacin
gyrA	8420	c.1119T>C	synonymous_variant	0.96	levofloxacin
gyrA	8420	c.1119T>C	synonymous_variant	0.96	moxifloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.98	levofloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.98	moxifloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.98	levofloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.98	moxifloxacin
gyrA	8462	c.1161A>G	synonymous_variant	0.98	levofloxacin
gyrA	8462	c.1161A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.98	levofloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.98	levofloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8486	c.1185T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8486	c.1185T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8489	c.1188A>G	synonymous_variant	0.97	levofloxacin
gyrA	8489	c.1188A>G	synonymous_variant	0.97	moxifloxacin
gyrA	8501	c.1200G>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8501	c.1200G>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8504	c.1203G>C	synonymous_variant	0.97	levofloxacin
gyrA	8504	c.1203G>C	synonymous_variant	0.97	moxifloxacin
gyrA	8513	c.1212C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8513	c.1212C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8516	c.1215T>C	synonymous_variant	0.97	levofloxacin
gyrA	8516	c.1215T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8519	c.1218A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8519	c.1218A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8520	c.1219C>T	synonymous_variant	0.97	levofloxacin
gyrA	8520	c.1219C>T	synonymous_variant	0.97	moxifloxacin
gyrA	8531	c.1230G>C	synonymous_variant	0.97	levofloxacin
gyrA	8531	c.1230G>C	synonymous_variant	0.97	moxifloxacin
gyrA	8543	c.1242C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8543	c.1242C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8552	c.1251_1254delCCGGinsGC	frameshift_variant&synonymous_variant	0.97	levofloxacin
gyrA	8552	c.1251_1254delCCGGinsGC	frameshift_variant&synonymous_variant	0.97	moxifloxacin
gyrA	8559	c.1258_1260delGGAinsAGGGC	frameshift_variant&missense_variant	1.0	levofloxacin
gyrA	8559	c.1258_1260delGGAinsAGGGC	frameshift_variant&missense_variant	1.0	moxifloxacin
gyrA	8588	p.Glu429Asp	missense_variant	1.0	levofloxacin
gyrA	8588	p.Glu429Asp	missense_variant	1.0	moxifloxacin
gyrA	8603	c.1302A>C	synonymous_variant	1.0	levofloxacin
gyrA	8603	c.1302A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8619	c.1318T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8619	c.1318T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8627	c.1326C>G	synonymous_variant	1.0	levofloxacin
gyrA	8627	c.1326C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8636	c.1335A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8636	c.1335A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8645	c.1344C>G	synonymous_variant	0.97	levofloxacin
gyrA	8645	c.1344C>G	synonymous_variant	0.97	moxifloxacin
gyrA	8651	c.1350C>G	synonymous_variant	1.0	levofloxacin
gyrA	8651	c.1350C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8655	p.Ile452Val	missense_variant	1.0	levofloxacin
gyrA	8655	p.Ile452Val	missense_variant	1.0	moxifloxacin
gyrA	8672	c.1371A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8672	c.1371A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8711	c.1410A>C	synonymous_variant	0.98	levofloxacin
gyrA	8711	c.1410A>C	synonymous_variant	0.98	moxifloxacin
gyrA	8714	c.1413A>G	synonymous_variant	0.98	levofloxacin
gyrA	8714	c.1413A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8729	c.1428T>C	synonymous_variant	0.98	levofloxacin
gyrA	8729	c.1428T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8747	c.1446A>G	synonymous_variant	0.98	levofloxacin
gyrA	8747	c.1446A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8751	p.Ala484Lys	missense_variant	0.97	levofloxacin
gyrA	8751	p.Ala484Lys	missense_variant	0.97	moxifloxacin
gyrA	8756	c.1455A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8756	c.1455A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8762	c.1461G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8762	c.1461G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8767	p.Arg489Lys	missense_variant	0.98	levofloxacin	Uncertain significance
gyrA	8767	p.Arg489Lys	missense_variant	0.98	moxifloxacin	Uncertain significance
gyrA	8783	c.1482G>T	synonymous_variant	0.98	levofloxacin
gyrA	8783	c.1482G>T	synonymous_variant	0.98	moxifloxacin
gyrA	8786	c.1485T>C	synonymous_variant	0.98	levofloxacin
gyrA	8786	c.1485T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8792	c.1491G>C	synonymous_variant	0.98	levofloxacin
gyrA	8792	c.1491G>C	synonymous_variant	0.98	moxifloxacin
gyrA	8796	c.1495_1497delATCinsGG	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8796	c.1495_1497delATCinsGG	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8801	c.1500G>C	synonymous_variant	1.0	levofloxacin
gyrA	8801	c.1500G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8810	c.1509A>C	synonymous_variant	1.0	levofloxacin
gyrA	8810	c.1509A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8813	p.Asp504Glu	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	8813	p.Asp504Glu	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	8828	c.1527T>C	synonymous_variant	1.0	levofloxacin
gyrA	8828	c.1527T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8829	c.1528T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8829	c.1528T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8852	c.1551T>C	synonymous_variant	0.97	levofloxacin
gyrA	8852	c.1551T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8858	c.1557T>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8858	c.1557T>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8867	c.1566A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8867	c.1566A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8897	c.1596T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrA	8897	c.1596T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	8900	c.1599G>C	synonymous_variant	0.95	levofloxacin
gyrA	8900	c.1599G>C	synonymous_variant	0.95	moxifloxacin
gyrA	8903	c.1602T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	8939	c.1638T>C	synonymous_variant	0.94	levofloxacin
gyrA	8939	c.1638T>C	synonymous_variant	0.94	moxifloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.94	levofloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.94	moxifloxacin
gyrA	8946	c.1645_1647delTTGinsCC	frameshift_variant&missense_variant	0.94	levofloxacin
gyrA	8946	c.1645_1647delTTGinsCC	frameshift_variant&missense_variant	0.94	moxifloxacin
gyrA	8967	p.Ala556Asn	missense_variant	0.93	levofloxacin
gyrA	8967	p.Ala556Asn	missense_variant	0.93	moxifloxacin
gyrA	8981	c.1680G>C	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	8981	c.1680G>C	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	8987	c.1686C>G	synonymous_variant	0.96	levofloxacin
gyrA	8987	c.1686C>G	synonymous_variant	0.96	moxifloxacin
gyrA	8990	c.1689C>G	synonymous_variant	0.95	levofloxacin
gyrA	8990	c.1689C>G	synonymous_variant	0.95	moxifloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.95	levofloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.95	moxifloxacin
gyrA	8998	p.Leu566Trp	missense_variant	0.95	levofloxacin	Uncertain significance
gyrA	8998	p.Leu566Trp	missense_variant	0.95	moxifloxacin	Uncertain significance
gyrA	9017	c.1716C>G	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	9017	c.1716C>G	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9029	c.1728T>G	synonymous_variant	1.0	levofloxacin
gyrA	9029	c.1728T>G	synonymous_variant	1.0	moxifloxacin
gyrA	9032	c.1731T>C	synonymous_variant	1.0	levofloxacin
gyrA	9032	c.1731T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9182	c.1881T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9182	c.1881T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9191	c.1890G>T	synonymous_variant	1.0	levofloxacin
gyrA	9191	c.1890G>T	synonymous_variant	1.0	moxifloxacin
gyrA	9200	c.1899A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9200	c.1899A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9206	c.1905C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9206	c.1905C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9207	p.Lys636Arg	missense_variant	1.0	levofloxacin
gyrA	9207	p.Lys636Arg	missense_variant	1.0	moxifloxacin
gyrA	9227	c.1926C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9227	c.1926C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9230	c.1929T>C	synonymous_variant	1.0	levofloxacin
gyrA	9230	c.1929T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9236	c.1935G>C	synonymous_variant	1.0	levofloxacin
gyrA	9236	c.1935G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9242	c.1941A>C	synonymous_variant	1.0	levofloxacin
gyrA	9242	c.1941A>C	synonymous_variant	1.0	moxifloxacin
gyrA	9252	p.Val651Ile	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	9252	p.Val651Ile	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	9263	c.1962C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9263	c.1962C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9267	p.Asn656Gly	missense_variant	1.0	levofloxacin
gyrA	9267	p.Asn656Gly	missense_variant	1.0	moxifloxacin
gyrA	9275	c.1974G>A	synonymous_variant	1.0	levofloxacin
gyrA	9275	c.1974G>A	synonymous_variant	1.0	moxifloxacin
gyrA	9284	c.1983T>G	synonymous_variant	1.0	levofloxacin
gyrA	9284	c.1983T>G	synonymous_variant	1.0	moxifloxacin
gyrA	9287	c.1986G>T	synonymous_variant	1.0	levofloxacin
gyrA	9287	c.1986G>T	synonymous_variant	1.0	moxifloxacin
gyrA	9296	c.1995T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9296	c.1995T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9304	p.Gly668Asp	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	9304	p.Gly668Asp	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	9311	c.2010C>T	synonymous_variant	1.0	levofloxacin
gyrA	9311	c.2010C>T	synonymous_variant	1.0	moxifloxacin
gyrA	9323	c.2022C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9323	c.2022C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9335	c.2034G>C	synonymous_variant	1.0	levofloxacin
gyrA	9335	c.2034G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9345	c.2044A>C	synonymous_variant	1.0	levofloxacin
gyrA	9345	c.2044A>C	synonymous_variant	1.0	moxifloxacin
gyrA	9356	c.2055G>A	synonymous_variant	0.98	levofloxacin
gyrA	9356	c.2055G>A	synonymous_variant	0.98	moxifloxacin
gyrA	9374	c.2073G>C	synonymous_variant	1.0	levofloxacin
gyrA	9374	c.2073G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9377	c.2076A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9377	c.2076A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9383	c.2082T>C	synonymous_variant	1.0	levofloxacin
gyrA	9383	c.2082T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9386	c.2085T>G	synonymous_variant	1.0	levofloxacin
gyrA	9386	c.2085T>G	synonymous_variant	1.0	moxifloxacin
gyrA	9395	c.2094G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9395	c.2094G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9398	c.2097T>C	synonymous_variant	1.0	levofloxacin
gyrA	9398	c.2097T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9419	c.2118T>C	synonymous_variant	0.98	levofloxacin
gyrA	9419	c.2118T>C	synonymous_variant	0.98	moxifloxacin
gyrA	9420	p.Ile707Ala	missense_variant	0.98	levofloxacin
gyrA	9420	p.Ile707Ala	missense_variant	0.98	moxifloxacin
gyrA	9455	c.2154T>C	synonymous_variant	0.98	levofloxacin
gyrA	9455	c.2154T>C	synonymous_variant	0.98	moxifloxacin
gyrA	9464	c.2163C>A	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	9464	c.2163C>A	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	9476	c.2175G>C	synonymous_variant	0.97	levofloxacin
gyrA	9476	c.2175G>C	synonymous_variant	0.97	moxifloxacin
gyrA	9479	c.2178G>C	synonymous_variant	0.97	levofloxacin
gyrA	9479	c.2178G>C	synonymous_variant	0.97	moxifloxacin
gyrA	9485	c.2184A>C	synonymous_variant	0.97	levofloxacin
gyrA	9485	c.2184A>C	synonymous_variant	0.97	moxifloxacin
gyrA	9488	c.2187G>T	synonymous_variant	0.97	levofloxacin
gyrA	9488	c.2187G>T	synonymous_variant	0.97	moxifloxacin
gyrA	9494	c.2193T>C	synonymous_variant	0.96	levofloxacin
gyrA	9494	c.2193T>C	synonymous_variant	0.96	moxifloxacin
gyrA	9497	c.2196G>C	synonymous_variant	0.96	levofloxacin
gyrA	9497	c.2196G>C	synonymous_variant	0.96	moxifloxacin
gyrA	9500	c.2199A>G	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	9500	c.2199A>G	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	9503	c.2202T>C	synonymous_variant	0.96	levofloxacin
gyrA	9503	c.2202T>C	synonymous_variant	0.96	moxifloxacin
gyrA	9509	c.2208G>C	synonymous_variant	0.96	levofloxacin
gyrA	9509	c.2208G>C	synonymous_variant	0.96	moxifloxacin
gyrA	9518	c.2217A>G	synonymous_variant	0.96	levofloxacin
gyrA	9518	c.2217A>G	synonymous_variant	0.96	moxifloxacin
gyrA	9527	c.2226A>G	synonymous_variant	0.96	levofloxacin
gyrA	9527	c.2226A>G	synonymous_variant	0.96	moxifloxacin
gyrA	9542	c.2241T>C	synonymous_variant	0.93	levofloxacin
gyrA	9542	c.2241T>C	synonymous_variant	0.93	moxifloxacin
fgd1	490851	c.69A>G	synonymous_variant	0.86	clofazimine
					pretomanid
					delamanid
fgd1	490853	p.Ala24Gly	missense_variant	0.86	clofazimine
					pretomanid
					delamanid
fgd1	490859	p.Ala26Glu	missense_variant	0.81	clofazimine
					pretomanid
					delamanid
fgd1	490869	c.87C>G	synonymous_variant	0.84	clofazimine
					pretomanid
					delamanid
fgd1	490890	c.108C>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	490899	c.117C>T	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490902	c.120T>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490905	c.123T>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490911	c.129T>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490917	c.135C>T	synonymous_variant	0.98	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fgd1	490921	p.Gln47Glu	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490932	c.150T>C	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490935	c.153C>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490962	c.180T>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490968	c.186C>T	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	490971	c.189A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	490974	c.192T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	490980	p.Asn66Lys	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491010	c.228C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491013	c.231C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491016	c.234C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491037	c.255C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491043	c.261T>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491049	c.267T>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491064	c.282A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491073	c.291C>T	synonymous_variant	0.97	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fgd1	491077	p.Asn99Asp	missense_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491082	c.300T>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491091	c.309T>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491094	c.312C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491106	c.324T>A	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491115	c.333G>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491121	c.339A>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491133	c.351A>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491144	p.Ala121Asp	missense_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491181	c.399T>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491187	c.405G>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491461	p.Lys227Arg	missense_variant	0.82	clofazimine
					pretomanid
					delamanid
fgd1	491472	c.690A>G	synonymous_variant	0.88	clofazimine
					pretomanid
					delamanid
fgd1	491487	c.705C>T	synonymous_variant	0.88	clofazimine
					pretomanid
					delamanid
fgd1	491496	c.714C>T	synonymous_variant	0.88	clofazimine
					pretomanid
					delamanid
fgd1	491499	c.717G>C	synonymous_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491502	p.Glu240Asp	missense_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491508	c.726A>G	synonymous_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491509	c.727T>C	synonymous_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491521	c.739C>A	synonymous_variant	0.84	clofazimine
					pretomanid
					delamanid
fgd1	491526	c.744T>C	synonymous_variant	0.85	clofazimine
					pretomanid
					delamanid
fgd1	491542	c.760T>C	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fgd1	491547	c.765A>C	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fgd1	491550	c.768T>C	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fgd1	491601	c.819T>C	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fgd1	491610	c.828A>G	synonymous_variant	0.93	clofazimine
					pretomanid
					delamanid
fgd1	491616	c.834A>G	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491620	p.Ile280Val	missense_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491643	c.861G>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491646	c.864G>A	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491649	c.867C>T	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	491655	c.873C>T	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	491658	c.876A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	491673	c.891A>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491676	c.894T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491679	c.897A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491687	p.Thr302Lys	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491697	c.915G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
mshA	575652	p.Arg102Pro	missense_variant	0.82	ethionamide
mshA	575652	p.Arg102Pro	missense_variant	0.82	isoniazid
mshA	575659	c.312A>G	synonymous_variant	0.87	ethionamide
mshA	575659	c.312A>G	synonymous_variant	0.87	isoniazid
mshA	575665	c.318G>A	synonymous_variant	0.89	ethionamide
mshA	575665	c.318G>A	synonymous_variant	0.89	isoniazid
mshA	575671	c.324G>C	synonymous_variant	0.91	ethionamide
mshA	575671	c.324G>C	synonymous_variant	0.91	isoniazid
mshA	575683	c.336G>C	synonymous_variant	0.93	ethionamide
mshA	575683	c.336G>C	synonymous_variant	0.93	isoniazid
mshA	575689	c.342G>C	synonymous_variant	0.94	ethionamide
mshA	575689	c.342G>C	synonymous_variant	0.94	isoniazid
mshA	575695	c.348C>G	synonymous_variant	0.94	ethionamide
mshA	575695	c.348C>G	synonymous_variant	0.94	isoniazid	Not assoc w R - Interim
mshA	575704	c.357T>C	synonymous_variant	0.95	ethionamide
mshA	575704	c.357T>C	synonymous_variant	0.95	isoniazid
mshA	575734	c.387T>G	synonymous_variant	0.96	ethionamide
mshA	575734	c.387T>G	synonymous_variant	0.96	isoniazid
mshA	575737	c.390T>C	synonymous_variant	0.96	ethionamide
mshA	575737	c.390T>C	synonymous_variant	0.96	isoniazid
mshA	575744	p.Ala133Thr	missense_variant	0.96	ethionamide
mshA	575744	p.Ala133Thr	missense_variant	0.96	isoniazid	Uncertain significance
mshA	575749	c.402C>G	synonymous_variant	0.95	ethionamide
mshA	575749	c.402C>G	synonymous_variant	0.95	isoniazid
mshA	575752	c.405G>C	synonymous_variant	0.98	ethionamide
mshA	575752	c.405G>C	synonymous_variant	0.98	isoniazid
mshA	575770	c.423G>C	synonymous_variant	1.0	ethionamide
mshA	575770	c.423G>C	synonymous_variant	1.0	isoniazid
mshA	575771	p.Val142Thr	missense_variant	1.0	ethionamide
mshA	575771	p.Val142Thr	missense_variant	1.0	isoniazid
mshA	575782	c.435G>C	synonymous_variant	1.0	ethionamide
mshA	575782	c.435G>C	synonymous_variant	1.0	isoniazid
mshA	575785	c.438T>C	synonymous_variant	1.0	ethionamide
mshA	575785	c.438T>C	synonymous_variant	1.0	isoniazid
mshA	575821	c.474G>C	synonymous_variant	0.98	ethionamide
mshA	575821	c.474G>C	synonymous_variant	0.98	isoniazid
mshA	575842	c.495G>A	synonymous_variant	0.96	ethionamide
mshA	575842	c.495G>A	synonymous_variant	0.96	isoniazid
mshA	575845	c.498C>G	synonymous_variant	0.96	ethionamide
mshA	575845	c.498C>G	synonymous_variant	0.96	isoniazid
mshA	575864	c.517T>C	synonymous_variant	0.96	ethionamide
mshA	575864	c.517T>C	synonymous_variant	0.96	isoniazid
mshA	575878	c.531A>G	synonymous_variant	0.95	ethionamide
mshA	575878	c.531A>G	synonymous_variant	0.95	isoniazid
mshA	575896	c.549G>C	synonymous_variant	0.94	ethionamide
mshA	575896	c.549G>C	synonymous_variant	0.94	isoniazid
mshA	575905	c.558G>C	synonymous_variant	0.93	ethionamide
mshA	575905	c.558G>C	synonymous_variant	0.93	isoniazid
mshA	575908	c.561A>G	synonymous_variant	0.92	ethionamide
mshA	575908	c.561A>G	synonymous_variant	0.92	isoniazid
mshA	575911	c.564G>T	synonymous_variant	0.92	ethionamide
mshA	575911	c.564G>T	synonymous_variant	0.92	isoniazid
mshA	575917	p.Asp190Glu	missense_variant	0.92	ethionamide
mshA	575917	p.Asp190Glu	missense_variant	0.92	isoniazid
mshA	575920	c.573C>T	synonymous_variant	0.92	ethionamide	Not assoc w R - Interim
mshA	575920	c.573C>T	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
mshA	575925	p.Gly193Ala	missense_variant	0.92	ethionamide
mshA	575925	p.Gly193Ala	missense_variant	0.92	isoniazid
mshA	575929	c.582C>G	synonymous_variant	0.92	ethionamide
mshA	575929	c.582C>G	synonymous_variant	0.92	isoniazid
mshA	575932	c.585G>A	synonymous_variant	0.92	ethionamide
mshA	575932	c.585G>A	synonymous_variant	0.92	isoniazid
mshA	575944	c.597T>C	synonymous_variant	0.92	ethionamide
mshA	575944	c.597T>C	synonymous_variant	0.92	isoniazid
mshA	575945	p.Thr200Ala	missense_variant	0.92	ethionamide
mshA	575945	p.Thr200Ala	missense_variant	0.92	isoniazid
mshA	575953	c.606G>C	synonymous_variant	0.91	ethionamide
mshA	575953	c.606G>C	synonymous_variant	0.91	isoniazid
mshA	575956	c.609G>A	synonymous_variant	0.91	ethionamide
mshA	575956	c.609G>A	synonymous_variant	0.91	isoniazid
ccsA	619615	c.-276C>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619629	c.-262G>C	upstream_gene_variant	0.85	capreomycin
					amikacin
					kanamycin
ccsA	619648	c.-243C>G	upstream_gene_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	619654	c.-237A>G	upstream_gene_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	619657	c.-234C>G	upstream_gene_variant	0.89	capreomycin
					amikacin
					kanamycin
ccsA	619669	c.-222G>T	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619672	c.-219A>G	upstream_gene_variant	0.87	capreomycin
					amikacin
					kanamycin
ccsA	619696	c.-195C>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619697	c.-194_-192delAGGinsCA	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619702	c.-189C>A	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619706	c.-185_-183delGTGinsAC	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619713	c.-178C>T	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619723	c.-168G>C	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619727	c.-164delAinsGC	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619732	c.-158delG	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619746	c.-145A>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619762	c.-129C>G	upstream_gene_variant	0.87	capreomycin
					amikacin
					kanamycin
ccsA	619763	c.-128C>T	upstream_gene_variant	0.83	capreomycin
					amikacin
					kanamycin
ccsA	619766	c.-125_-123delACGinsGC	upstream_gene_variant	0.83	capreomycin
					amikacin
					kanamycin
ccsA	619774	c.-117C>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619783	c.-108C>G	upstream_gene_variant	0.82	capreomycin
					amikacin
					kanamycin
ccsA	619794	c.-97C>A	upstream_gene_variant	0.8	capreomycin
					amikacin
					kanamycin
ccsA	620238	c.348G>C	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620247	p.Leu119Phe	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620249	p.Ser120Cys	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620253	c.363G>C	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620256	c.366C>G	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620257	p.Ile123Val	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620264	p.Gly125Ala	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620268	c.378G>C	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620271	c.381C>G	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620283	c.393T>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620284	p.Ala132Pro	missense_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620288	p.Arg133Gln	missense_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620295	c.405G>C	synonymous_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620296	p.Pro136Ala	missense_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620307	c.417C>G	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620311	p.Leu141Val	missense_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620316	c.426G>C	synonymous_variant	0.96	capreomycin
					amikacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
ccsA	620337	c.447C>G	synonymous_variant	0.97	capreomycin
					amikacin
					kanamycin
ccsA	620340	c.450C>G	synonymous_variant	0.96	capreomycin
					amikacin
					kanamycin
ccsA	620346	c.456C>G	synonymous_variant	0.96	capreomycin
					amikacin
					kanamycin
ccsA	620349	c.459A>C	synonymous_variant	0.96	capreomycin
					amikacin
					kanamycin
ccsA	620362	p.Ala158Thr	missense_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620367	c.477T>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620388	c.498A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620409	c.519C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620412	c.522T>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620415	c.525T>C	synonymous_variant	1.0	capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
ccsA	620436	c.546T>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620439	c.549T>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620442	c.552G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620445	c.555A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620625	c.735A>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620631	c.741T>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620634	c.744C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620649	c.759A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620652	c.762C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620670	c.780C>T	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620694	c.804C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620698	p.Val270Ile	missense_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620709	c.819G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620710	c.820_822delGTGinsAC	frameshift_variant&missense_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620721	c.831G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620730	c.840C>T	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620733	c.843G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620736	c.846G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620739	c.849A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620748	c.858T>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620754	c.864G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620758	p.Arg290Lys	missense_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620778	c.888T>C	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620784	c.894C>A	synonymous_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620793	c.903G>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620796	c.906C>G	synonymous_variant	0.92	capreomycin
					amikacin
					kanamycin
ccsA	620802	c.912C>G	synonymous_variant	0.91	capreomycin
					amikacin
					kanamycin
Rv0565c	657596	c.-126G>C	upstream_gene_variant	1.0	ethionamide
Rv0565c	657620	c.-150C>T	upstream_gene_variant	1.0	ethionamide
Rv0565c	657635	c.-167_-165delAGCinsTCG	upstream_gene_variant	1.0	ethionamide
Rv0565c	657640	c.-170A>T	upstream_gene_variant	1.0	ethionamide
Rv0565c	657641	c.-171C>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657647	c.-177C>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657670	c.-200A>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657671	c.-201A>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657678	c.-209_-208delAAinsGG	upstream_gene_variant	1.0	ethionamide
Rv0565c	657689	c.-220_-219delCAinsAG	upstream_gene_variant	0.98	ethionamide
Rv0565c	657734	c.-264T>C	upstream_gene_variant	1.0	ethionamide
nusG	734421	c.168A>C	synonymous_variant	1.0	rifampicin
nusG	734424	c.171G>C	synonymous_variant	1.0	rifampicin
nusG	734439	c.186C>G	synonymous_variant	1.0	rifampicin
nusG	734442	c.189G>A	synonymous_variant	1.0	rifampicin
nusG	734451	c.198G>C	synonymous_variant	1.0	rifampicin
nusG	734454	c.201A>G	synonymous_variant	1.0	rifampicin
nusG	734460	c.207G>C	synonymous_variant	1.0	rifampicin
nusG	734472	c.219T>C	synonymous_variant	1.0	rifampicin
nusG	734475	c.222T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734499	c.246G>C	synonymous_variant	1.0	rifampicin
nusG	734505	c.252G>C	synonymous_variant	0.97	rifampicin
nusG	734532	c.279A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
nusG	734541	c.288A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
nusG	734559	c.306T>C	synonymous_variant	0.96	rifampicin
nusG	734580	c.327T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
nusG	734814	c.561G>C	synonymous_variant	0.8	rifampicin
nusG	734820	c.567A>G	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
nusG	734826	c.573A>C	synonymous_variant	0.8	rifampicin
nusG	734847	c.594T>C	synonymous_variant	0.9	rifampicin
nusG	734853	c.600A>G	synonymous_variant	0.9	rifampicin
nusG	734854	c.601T>C	synonymous_variant	0.9	rifampicin
nusG	734862	c.609C>G	synonymous_variant	0.9	rifampicin
nusG	734863	p.Thr204Ser	missense_variant	0.9	rifampicin
rpoB	760139	c.333A>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760140	p.Pro112Ser	missense_variant	0.92	rifampicin
rpoB	760148	c.342C>T	synonymous_variant	0.94	rifampicin
rpoB	760184	c.378A>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	760196	c.390C>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	760208	p.Ile134Met	missense_variant	0.9	rifampicin
rpoB	760212	p.Asn136Ala	missense_variant	0.9	rifampicin
rpoB	760215	c.409_411delAACinsGG	frameshift_variant&missense_variant	0.9	rifampicin
rpoB	760219	p.Thr138Ser	missense_variant	0.9	rifampicin
rpoB	760223	c.417T>C	synonymous_variant	0.91	rifampicin
rpoB	760235	c.429T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760244	c.438G>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	760283	c.477G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760298	c.492G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760310	c.504G>C	synonymous_variant	0.97	rifampicin
rpoB	760316	c.510C>G	synonymous_variant	0.97	rifampicin
rpoB	760317	c.511_513delAGCinsTCG	synonymous_variant	0.97	rifampicin
rpoB	760328	c.522G>T	synonymous_variant	0.97	rifampicin
rpoB	760331	c.525G>C	synonymous_variant	1.0	rifampicin
rpoB	760340	c.534G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760361	c.555T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760406	c.600G>C	synonymous_variant	0.96	rifampicin
rpoB	760407	p.Ser201Gly	missense_variant	0.96	rifampicin	Uncertain significance
rpoB	760424	c.618C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760430	c.624T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760454	c.648C>G	synonymous_variant	0.96	rifampicin
rpoB	760475	c.669A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760478	c.672C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760481	c.675G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760484	c.678A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760487	c.681G>C	synonymous_variant	0.96	rifampicin
rpoB	760502	c.696C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760522	p.Ser239Asn	missense_variant	0.98	rifampicin	Uncertain significance
rpoB	760532	c.726T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760533	p.Val243Thr	missense_variant	0.97	rifampicin
rpoB	760547	c.741G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760551	c.745_746delTCinsAG	synonymous_variant	0.97	rifampicin
rpoB	760563	c.757delCinsAT	frameshift_variant&synonymous_variant	1.0	rifampicin
rpoB	760566	p.Ser254Ala	missense_variant	1.0	rifampicin
rpoB	760567	c.762delG	frameshift_variant	1.0	rifampicin
rpoB	760591	p.Val262Ala	missense_variant	1.0	rifampicin
rpoB	760608	c.802C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760611	c.805T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760634	c.828T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760646	c.840C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760655	c.849A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760661	c.855A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760670	c.864G>C	synonymous_variant	1.0	rifampicin
rpoB	760674	c.868T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760679	c.873A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760683	c.877T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760724	c.918T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760916	c.1110C>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760925	c.1119T>C	synonymous_variant	0.95	rifampicin
rpoB	760946	c.1140A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760958	c.1152G>C	synonymous_variant	0.94	rifampicin
rpoB	760965	p.Met387Leu	missense_variant	0.92	rifampicin	Uncertain significance
rpoB	760970	c.1164G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760973	c.1167G>C	synonymous_variant	0.92	rifampicin
rpoB	760982	c.1176G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760988	c.1182C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760991	c.1185G>C	synonymous_variant	0.93	rifampicin
rpoB	760997	c.1191G>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761015	c.1209G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761027	c.1221A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761036	c.1230G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761037	c.1231T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761051	c.1245G>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761054	c.1248G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761057	c.1251G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761060	c.1254C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761063	c.1257C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761087	c.1281C>G	synonymous_variant	0.93	rifampicin
rpoB	761088	c.1282_1284delAGCinsTCG	synonymous_variant	0.93	rifampicin
rpoB	761097	c.1291_1293delAGCinsTCG	synonymous_variant	0.93	rifampicin
rpoB	761102	c.1296A>G	synonymous_variant	0.93	rifampicin
rpoB	761147	c.1341C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761153	c.1347G>C	synonymous_variant	1.0	rifampicin
rpoB	761165	c.1359G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	761168	c.1362C>G	synonymous_variant	0.98	rifampicin
rpoB	761174	c.1368T>C	synonymous_variant	1.0	rifampicin
rpoB	761180	c.1374A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761189	c.1383T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761195	c.1389G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761198	c.1392G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761204	c.1398C>G	synonymous_variant	0.97	rifampicin
rpoB	761217	c.1411_1413delCCGinsGC	frameshift_variant&missense_variant	0.94	rifampicin
rpoB	761220	c.1414_1416delTCGinsAGC	synonymous_variant	0.94	rifampicin
rpoB	761249	c.1443A>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761255	c.1449T>C	synonymous_variant	0.93	rifampicin
rpoB	761261	c.1455G>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761264	c.1458C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761300	c.1494G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	761303	c.1497G>A	synonymous_variant	0.89	rifampicin
rpoB	761327	c.1521A>G	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	761345	c.1539G>C	synonymous_variant	0.88	rifampicin
rpoB	761357	c.1551G>A	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	761362	p.Ser519Thr	missense_variant	0.95	rifampicin
rpoB	761366	c.1560C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761375	c.1569G>C	synonymous_variant	0.95	rifampicin
rpoB	761403	p.His533Tyr	missense_variant	1.0	rifampicin
rpoB	761537	c.1731C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761555	c.1749G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761558	c.1752C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761561	c.1755C>G	synonymous_variant	0.96	rifampicin
rpoB	761570	c.1764T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761573	c.1767C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761600	c.1794T>C	synonymous_variant	1.0	rifampicin
rpoB	761606	c.1800C>G	synonymous_variant	0.97	rifampicin
rpoB	761612	c.1806G>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761615	c.1809A>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761627	c.1821C>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761636	c.1830G>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761645	c.1839C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761648	c.1842T>C	synonymous_variant	0.94	rifampicin
rpoB	761666	c.1860G>C	synonymous_variant	0.95	rifampicin
rpoB	761669	c.1863C>T	synonymous_variant	0.94	rifampicin
rpoB	761675	c.1869G>C	synonymous_variant	0.95	rifampicin
rpoB	761682	c.1876C>T	synonymous_variant	0.94	rifampicin
rpoB	761687	c.1881C>T	synonymous_variant	0.94	rifampicin
rpoB	761690	c.1884G>C	synonymous_variant	0.94	rifampicin
rpoB	761705	c.1899C>T	synonymous_variant	0.93	rifampicin
rpoB	761723	p.Glu639Asp	missense_variant	0.9	rifampicin	Not assoc w R
rpoB	761724	c.1918_1920delGAAinsAC	frameshift_variant&missense_variant	0.89	rifampicin
rpoB	761727	p.Ser641Ala	missense_variant	0.89	rifampicin
rpoB	761732	c.1926C>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	761735	c.1929C>G	synonymous_variant	0.91	rifampicin
rpoB	761747	c.1941G>C	synonymous_variant	0.93	rifampicin
rpoB	761750	c.1944G>C	synonymous_variant	0.91	rifampicin
rpoB	761765	c.1959T>C	synonymous_variant	0.97	rifampicin
rpoB	761772	p.His656Ala	missense_variant	0.97	rifampicin
rpoB	761778	p.Asn658Asp	missense_variant	0.97	rifampicin
rpoB	761791	p.Arg662Gln	missense_variant	0.95	rifampicin
rpoB	761813	c.2007T>C	synonymous_variant	0.95	rifampicin
rpoB	761834	c.2028T>C	synonymous_variant	0.91	rifampicin
rpoB	761847	p.Cys681Arg	missense_variant	0.92	rifampicin	Uncertain significance
rpoB	761852	c.2046C>G	synonymous_variant	0.92	rifampicin
rpoB	761858	c.2052G>C	synonymous_variant	0.92	rifampicin
rpoB	761864	c.2058G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761873	c.2067A>G	synonymous_variant	0.92	rifampicin
rpoB	761876	c.2070C>G	synonymous_variant	0.92	rifampicin
rpoB	761885	c.2079T>C	synonymous_variant	0.92	rifampicin
rpoB	761891	c.2085G>C	synonymous_variant	0.92	rifampicin
rpoB	761903	c.2097T>G	synonymous_variant	0.93	rifampicin
rpoB	761906	c.2100C>G	synonymous_variant	0.93	rifampicin
rpoB	761909	c.2103T>C	synonymous_variant	0.93	rifampicin
rpoB	761912	c.2106T>C	synonymous_variant	0.93	rifampicin
rpoB	761915	p.Asp703Glu	missense_variant	0.93	rifampicin
rpoB	761916	p.Asp704Asn	missense_variant	0.93	rifampicin
rpoB	761948	c.2142G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761951	c.2145G>C	synonymous_variant	0.96	rifampicin
rpoB	761954	c.2148C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761999	c.2193G>C	synonymous_variant	1.0	rifampicin
rpoB	762008	c.2202C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762014	c.2208C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762017	c.2211A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762053	c.2247T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762062	c.2256T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762101	c.2295C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762114	p.Ile770Val	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	762122	c.2316C>T	synonymous_variant	1.0	rifampicin
rpoB	762131	c.2325C>G	synonymous_variant	1.0	rifampicin
rpoB	762140	c.2334G>C	synonymous_variant	1.0	rifampicin
rpoB	762143	c.2337T>C	synonymous_variant	1.0	rifampicin
rpoB	762149	c.2343G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762158	c.2352G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762167	c.2361T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762176	c.2370T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762185	c.2379G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762233	c.2427G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762257	c.2451C>G	synonymous_variant	1.0	rifampicin
rpoB	762275	c.2469C>G	synonymous_variant	1.0	rifampicin
rpoB	762284	c.2478G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762293	c.2487T>G	synonymous_variant	1.0	rifampicin
rpoB	762314	c.2508C>T	synonymous_variant	1.0	rifampicin
rpoB	762317	c.2511A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762338	c.2532T>C	synonymous_variant	1.0	rifampicin
rpoB	762341	c.2535G>C	synonymous_variant	1.0	rifampicin
rpoB	762347	c.2541T>C	synonymous_variant	1.0	rifampicin
rpoB	762362	p.Glu852Asp	missense_variant	1.0	rifampicin
rpoB	762369	c.2563T>C	synonymous_variant	1.0	rifampicin
rpoC	762374	c.-996G>C	upstream_gene_variant	1.0	rifampicin
rpoC	762380	c.-990T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762395	c.-975G>C	upstream_gene_variant	1.0	rifampicin
rpoC	762398	c.-972T>C	upstream_gene_variant	0.98	rifampicin
rpoC	762401	c.-969G>C	upstream_gene_variant	1.0	rifampicin
rpoB	762404	c.2598T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762407	c.-963G>C	upstream_gene_variant	1.0	rifampicin
rpoB	762410	c.2604T>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	762416	c.2610A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762434	c.-936T>C	upstream_gene_variant	1.0	rifampicin
rpoB	762449	c.2643C>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762452	c.2646G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762470	c.2664G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	762491	c.2685T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	762512	c.-858C>G	upstream_gene_variant	0.88	rifampicin
rpoC	762527	c.-843G>C	upstream_gene_variant	0.95	rifampicin
rpoC	762533	c.-837T>C	upstream_gene_variant	0.94	rifampicin
rpoC	762536	c.-834T>C	upstream_gene_variant	1.0	rifampicin
rpoB	762537	c.2731_2733delTTGinsCC	frameshift_variant&missense_variant	1.0	rifampicin
rpoC	762551	c.-819C>T	upstream_gene_variant	1.0	rifampicin
rpoB	762785	p.Asp993Glu	missense_variant	0.9	rifampicin	Uncertain significance
rpoB	762786	p.Val994Lys	missense_variant	0.9	rifampicin
rpoB	762798	p.Ala998Ser	missense_variant	0.93	rifampicin
rpoB	762818	c.3012C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762820	p.Phe1005Tyr	missense_variant	0.97	rifampicin
rpoB	762827	c.3021G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	762857	c.3051C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762863	c.3057T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762879	c.3073_3075delATGinsCC	frameshift_variant&missense_variant	1.0	rifampicin
rpoB	762929	c.3123G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762995	c.3189G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763004	c.3198G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763007	c.3201C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763028	c.3222T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763031	c.3225T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763034	c.3228C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763040	c.3234C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763070	c.3264T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763085	c.3279C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763115	c.3309T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763127	c.3321G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763133	c.-237G>C	upstream_gene_variant	1.0	rifampicin
rpoB	763136	c.3330C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763139	c.-231C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763142	c.-228C>G	upstream_gene_variant	1.0	rifampicin
rpoC	763158	c.-212C>T	upstream_gene_variant	1.0	rifampicin
rpoB	763166	c.3360A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763179	c.-191C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763202	c.-168A>G	upstream_gene_variant	1.0	rifampicin
rpoC	763205	c.-165G>T	upstream_gene_variant	1.0	rifampicin
rpoC	763206	c.-164_-162delAGTinsTCG	upstream_gene_variant	1.0	rifampicin
rpoB	763214	c.3408T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	763217	c.-153G>C	upstream_gene_variant	1.0	rifampicin
rpoC	763226	c.-144A>G	upstream_gene_variant	1.0	rifampicin
rpoB	763227	p.Leu1141Met	missense_variant	1.0	rifampicin
rpoB	763235	p.Glu1143Asp	missense_variant	1.0	rifampicin
rpoB	763238	c.3432T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763241	p.Glu1145Asp	missense_variant	1.0	rifampicin
rpoC	763250	c.-120C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763251	c.-119C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763259	c.-111G>C	upstream_gene_variant	1.0	rifampicin
rpoB	763268	c.3462C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763283	c.3477T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763284	c.-86C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763289	c.-81C>G	upstream_gene_variant	1.0	rifampicin
rpoC	763375	c.6C>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763396	c.27A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763402	c.33C>G	synonymous_variant	1.0	rifampicin
rpoC	763405	c.36C>T	synonymous_variant	0.98	rifampicin
rpoC	763408	c.39T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763414	c.45T>C	synonymous_variant	1.0	rifampicin
rpoC	763417	c.48C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763430	c.61A>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	763433	c.64_66delCAAinsAC	frameshift_variant&missense_variant	1.0	rifampicin
rpoC	763443	p.Tyr25Phe	missense_variant	1.0	rifampicin
rpoC	763447	c.78C>T	synonymous_variant	1.0	rifampicin
rpoC	763456	c.87A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763468	c.99G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763486	c.117T>G	synonymous_variant	1.0	rifampicin
rpoC	763528	c.159G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763546	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763573	c.204G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763594	c.225C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763660	c.291T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763675	c.306C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763702	c.333C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763703	c.334_336delTCGinsAGC	synonymous_variant	1.0	rifampicin
rpoC	763711	c.342G>C	synonymous_variant	1.0	rifampicin
rpoC	763717	c.348T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763723	c.354G>C	synonymous_variant	1.0	rifampicin
rpoC	763732	c.363C>G	synonymous_variant	1.0	rifampicin
rpoC	763735	c.366G>C	synonymous_variant	1.0	rifampicin
rpoC	763741	c.372C>T	synonymous_variant	1.0	rifampicin
rpoC	763744	c.375G>C	synonymous_variant	1.0	rifampicin
rpoC	763765	c.396T>C	synonymous_variant	1.0	rifampicin
rpoC	763768	c.399C>T	synonymous_variant	1.0	rifampicin
rpoC	763774	c.405G>C	synonymous_variant	1.0	rifampicin
rpoC	763781	p.Ser138Glu	missense_variant	1.0	rifampicin
rpoC	763807	c.438T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763813	c.444C>G	synonymous_variant	0.99	rifampicin
rpoC	763816	c.447C>G	synonymous_variant	0.99	rifampicin
rpoC	763822	c.453C>G	synonymous_variant	0.99	rifampicin
rpoC	763831	c.462A>G	synonymous_variant	0.98	rifampicin
rpoC	763837	c.468G>C	synonymous_variant	0.98	rifampicin
rpoC	763840	c.471G>C	synonymous_variant	0.98	rifampicin
rpoC	763849	c.480G>A	synonymous_variant	0.98	rifampicin
rpoC	763855	c.486C>T	synonymous_variant	0.96	rifampicin
rpoC	763858	c.489A>G	synonymous_variant	0.96	rifampicin
rpoC	763867	c.498C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763870	c.501C>T	synonymous_variant	0.96	rifampicin
rpoC	763871	p.Gly168Ser	missense_variant	0.96	rifampicin
rpoC	763876	p.Glu169Asp	missense_variant	0.96	rifampicin
rpoC	763879	c.510A>G	synonymous_variant	0.96	rifampicin
rpoC	763888	c.519G>T	synonymous_variant	0.95	rifampicin
rpoC	763894	c.525A>G	synonymous_variant	0.95	rifampicin
rpoC	763900	c.531G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763910	p.Leu181Met	missense_variant	0.96	rifampicin
rpoC	763933	c.564C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763940	p.Ala191Ser	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	763945	c.576T>C	synonymous_variant	0.95	rifampicin
rpoC	763947	p.Ala193Val	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	763951	c.582G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763960	c.591T>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763978	c.609C>T	synonymous_variant	0.96	rifampicin
rpoC	763996	c.627T>C	synonymous_variant	0.97	rifampicin
rpoC	764005	c.636G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764024	c.655_657delTTGinsCC	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	764032	p.Asp221Glu	missense_variant	1.0	rifampicin
rpoC	764040	p.Ser224Asn	missense_variant	1.0	rifampicin
rpoC	764044	c.675T>C	synonymous_variant	1.0	rifampicin
rpoC	764059	c.690G>C	synonymous_variant	1.0	rifampicin
rpoC	764083	c.714A>G	synonymous_variant	0.98	rifampicin
rpoC	764084	p.Asn239Val	missense_variant	0.98	rifampicin
rpoC	764098	c.729A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764101	c.732C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764102	p.Val245Gln	missense_variant	0.98	rifampicin
rpoC	764131	c.762T>C	synonymous_variant	0.96	rifampicin
rpoC	764147	c.778_780delTCGinsGC	frameshift_variant&missense_variant	0.95	rifampicin
rpoC	764153	p.Gln262Lys	missense_variant	0.95	rifampicin
rpoC	764156	p.Lys263Arg	missense_variant	0.95	rifampicin
rpoC	764188	c.819A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764203	c.834G>C	synonymous_variant	0.95	rifampicin
rpoC	764206	p.Asp279Glu	missense_variant	0.95	rifampicin
rpoC	764207	p.Val280Thr	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	764215	c.846A>T	synonymous_variant	0.95	rifampicin
rpoC	764217	p.Asn283Ser	missense_variant	0.97	rifampicin
rpoC	764242	c.873C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764245	c.876C>G	synonymous_variant	0.95	rifampicin
rpoC	764248	c.879C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764257	c.888G>C	synonymous_variant	0.95	rifampicin
rpoC	764266	c.897T>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	764269	c.900G>T	synonymous_variant	0.93	rifampicin
rpoC	764272	c.903G>C	synonymous_variant	0.94	rifampicin
rpoC	764278	c.909A>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764285	p.Gly306Ser	missense_variant	0.94	rifampicin
rpoC	764320	c.951C>T	synonymous_variant	0.95	rifampicin
rpoC	764338	c.969G>A	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764365	c.996C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764383	c.1014C>G	synonymous_variant	0.96	rifampicin
rpoC	764387	c.1018T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764405	c.1036_1038delAGGinsCC	frameshift_variant&missense_variant	0.96	rifampicin
rpoC	764410	c.1041G>C	synonymous_variant	0.97	rifampicin
rpoC	764431	c.1062G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764434	c.1065A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764452	c.1083T>C	synonymous_variant	0.96	rifampicin
rpoC	764458	c.1089G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764461	c.1092A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764485	c.1116G>C	synonymous_variant	0.96	rifampicin
rpoC	764491	c.1122G>T	synonymous_variant	0.97	rifampicin
rpoC	764497	c.1128A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764500	c.1131C>G	synonymous_variant	0.96	rifampicin
rpoC	764521	c.1152T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764527	c.1158C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764536	c.1167G>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764539	c.1170C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764575	c.1206T>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764578	c.1209C>G	synonymous_variant	0.95	rifampicin
rpoC	764585	c.1216_1218delCTCinsTG	frameshift_variant&missense_variant	0.95	rifampicin
rpoC	764611	c.1242G>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764632	c.1263T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764686	c.1317C>T	synonymous_variant	0.96	rifampicin
rpoC	764713	c.1344G>A	synonymous_variant	0.96	rifampicin
rpoC	764746	c.1377G>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764752	c.1383G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764758	c.1389C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764791	c.1422C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764803	c.1434C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764809	c.1440C>T	synonymous_variant	0.95	rifampicin	Not assoc w R
rpoC	764812	c.1443C>G	synonymous_variant	0.96	rifampicin
rpoC	764815	c.1446A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764824	c.1455T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764857	c.1488G>T	synonymous_variant	0.97	rifampicin
rpoC	764858	c.1489T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764875	c.1506C>G	synonymous_variant	0.98	rifampicin
rpoC	764878	c.1509C>G	synonymous_variant	0.98	rifampicin
rpoC	764887	c.1518G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764888	c.1519_1521delTTGinsCC	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	764893	c.1524T>C	synonymous_variant	0.99	rifampicin
rpoC	764911	c.1542A>G	synonymous_variant	0.99	rifampicin
rpoC	764923	c.1554A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764932	c.1563C>G	synonymous_variant	0.98	rifampicin
rpoC	764948	c.1579T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764968	c.1599T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764983	c.1614T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765007	c.1638T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765008	c.1639T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765011	c.1642_1644delAGCinsTCG	synonymous_variant	1.0	rifampicin
rpoC	765016	c.1647C>G	synonymous_variant	1.0	rifampicin
rpoC	765019	c.1650A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765034	c.1665T>G	synonymous_variant	1.0	rifampicin
rpoC	765040	c.1671T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765041	c.1672T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765047	c.1678T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765052	c.1683C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765055	c.1686C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765076	c.1707A>G	synonymous_variant	1.0	rifampicin
rpoC	765079	c.1710T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765082	c.1713G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765089	c.1720T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765103	c.1734G>T	synonymous_variant	1.0	rifampicin
rpoC	765349	c.1980T>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	765357	p.Met663Thr	missense_variant	0.9	rifampicin
rpoC	765359	p.Ala664Thr	missense_variant	0.9	rifampicin
rpoC	765367	c.1998C>G	synonymous_variant	0.93	rifampicin
rpoC	765397	c.2028G>T	synonymous_variant	0.93	rifampicin
rpoC	765402	c.2035_2038delCTGG	frameshift_variant	0.93	rifampicin
rpoC	765409	c.2041_2042insCAGT	frameshift_variant	0.93	rifampicin
rpoC	765425	p.Lys686Glu	missense_variant	0.91	rifampicin
rpoC	765451	c.2082C>G	synonymous_variant	0.9	rifampicin
rpoC	765452	p.Ala695Arg	missense_variant	0.9	rifampicin
rpoC	765458	p.Ile697Val	missense_variant	0.91	rifampicin	Uncertain significance
rpoC	765466	c.2097C>T	synonymous_variant	0.92	rifampicin
rpoC	765478	c.2109T>G	synonymous_variant	0.92	rifampicin
rpoC	765496	c.2127C>G	synonymous_variant	0.92	rifampicin
rpoC	765499	c.2130C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	765547	c.2178C>T	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoC	765548	c.2179_2181delAGCinsTCG	synonymous_variant	0.79	rifampicin
rpoC	765553	c.2184C>T	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoC	765556	c.2187G>C	synonymous_variant	0.79	rifampicin
rpoC	765559	c.2190G>C	synonymous_variant	0.79	rifampicin
rpoC	765590	p.Arg741Glu	missense_variant	0.85	rifampicin
rpoC	765596	p.Lys743Gln	missense_variant	0.77	rifampicin
rpoC	765772	c.2403C>G	synonymous_variant	0.87	rifampicin
rpoC	765793	c.2424C>G	synonymous_variant	0.93	rifampicin
rpoC	765796	c.2427C>T	synonymous_variant	0.94	rifampicin
rpoC	765805	c.2436C>G	synonymous_variant	0.94	rifampicin
rpoC	765811	c.2442T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765814	c.2445A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765826	c.2457T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765875	p.Val836Ile	missense_variant	0.98	rifampicin	Uncertain significance
rpoC	765886	c.2517C>G	synonymous_variant	0.99	rifampicin
rpoC	765892	c.2523T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765937	c.2568T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765947	c.2578T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765961	c.2592G>T	synonymous_variant	0.98	rifampicin
rpoC	765962	c.2593_2595delTTGinsCT	frameshift_variant&synonymous_variant	0.97	rifampicin
rpoC	765967	c.2598C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765973	c.2604C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765979	c.2610C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765982	c.2613C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765994	c.2625A>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766012	c.2643C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	766021	c.2652G>C	synonymous_variant	0.94	rifampicin
rpoC	766043	p.Gln892Glu	missense_variant	0.88	rifampicin
rpoC	766270	c.2901G>C	synonymous_variant	0.89	rifampicin
rpoC	766273	c.2904T>C	synonymous_variant	0.89	rifampicin
rpoC	766280	p.Ser971Gly	missense_variant	0.9	rifampicin
rpoC	766298	p.Thr977Leu	missense_variant	0.92	rifampicin
rpoC	766309	c.2940G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	766315	c.2946C>G	synonymous_variant	0.92	rifampicin
rpoC	766321	c.2952C>G	synonymous_variant	0.92	rifampicin
rpoC	766324	c.2955C>G	synonymous_variant	0.92	rifampicin
rpoC	766333	c.2964G>C	synonymous_variant	0.93	rifampicin
rpoC	766345	c.2976T>C	synonymous_variant	0.95	rifampicin
rpoC	766348	c.2979A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766363	c.2994G>C	synonymous_variant	1.0	rifampicin
rpoC	766369	c.3000C>G	synonymous_variant	1.0	rifampicin
rpoC	766384	c.3015A>G	synonymous_variant	1.0	rifampicin
rpoC	766393	c.3024C>G	synonymous_variant	1.0	rifampicin
rpoC	766411	c.3042C>G	synonymous_variant	1.0	rifampicin
rpoC	766423	c.3054T>C	synonymous_variant	1.0	rifampicin
rpoC	766428	c.3060_3061insACC	conservative_inframe_insertion	1.0	rifampicin
rpoC	766432	c.3063T>C	synonymous_variant	1.0	rifampicin
rpoC	766434	c.3065_3066delAGinsGCAGC	missense_variant&conservative_inframe_insertion	1.0	rifampicin
rpoC	766456	c.3087C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766459	c.3090G>C	synonymous_variant	1.0	rifampicin
rpoC	766480	c.3111C>G	synonymous_variant	1.0	rifampicin
rpoC	766483	c.3114G>C	synonymous_variant	1.0	rifampicin
rpoC	766486	c.3117A>G	synonymous_variant	1.0	rifampicin
rpoC	766492	c.3123T>G	synonymous_variant	1.0	rifampicin
rpoC	766494	p.Gly1042Asp	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	766517	p.Thr1050Ser	missense_variant	0.97	rifampicin
rpoC	766522	c.3153C>T	synonymous_variant	0.96	rifampicin
rpoC	766528	c.3159T>G	synonymous_variant	0.94	rifampicin
rpoC	766530	p.Arg1054Gln	missense_variant	0.87	rifampicin
rpoC	766540	p.Asp1057Glu	missense_variant	0.91	rifampicin
rpoC	766672	c.3303T>C	synonymous_variant	0.88	rifampicin
rpoC	766681	c.3312C>T	synonymous_variant	0.9	rifampicin
rpoC	766693	c.3324C>T	synonymous_variant	0.92	rifampicin
rpoC	766714	c.3345G>C	synonymous_variant	0.93	rifampicin
rpoC	766726	c.3357T>C	synonymous_variant	0.94	rifampicin
rpoC	766733	c.3364C>T	synonymous_variant	0.95	rifampicin
rpoC	766738	c.3369G>T	synonymous_variant	0.94	rifampicin
rpoC	766741	c.3372G>C	synonymous_variant	0.95	rifampicin
rpoC	766750	c.3381C>G	synonymous_variant	0.98	rifampicin
rpoC	766765	c.3396A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766771	c.3402G>C	synonymous_variant	1.0	rifampicin
rpoC	766774	c.3405T>C	synonymous_variant	1.0	rifampicin
rpoC	766775	p.Arg1136Lys	missense_variant	1.0	rifampicin
rpoC	766801	c.3432C>T	synonymous_variant	0.98	rifampicin
rpoC	766804	c.3435A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766843	c.3474T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766846	c.3477C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766858	c.3489C>G	synonymous_variant	0.97	rifampicin
rpoC	766861	c.3492G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766864	c.3495G>C	synonymous_variant	0.97	rifampicin
rpoC	766867	c.3498C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766894	c.3525T>C	synonymous_variant	0.97	rifampicin
rpoC	766895	c.3526T>C	synonymous_variant	0.97	rifampicin
rpoC	766900	c.3531T>C	synonymous_variant	0.97	rifampicin
rpoC	766907	c.3538C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766911	p.Ile1181Thr	missense_variant	0.97	rifampicin
rpoC	766915	p.Asp1182Glu	missense_variant	0.97	rifampicin
rpoC	766918	c.3549C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766933	c.3564A>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766942	c.3573C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766945	c.3576A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766951	c.3582G>T	synonymous_variant	0.99	rifampicin
rpoC	766963	c.3594T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766978	c.3609C>T	synonymous_variant	1.0	rifampicin
rpoC	766981	c.3612T>C	synonymous_variant	1.0	rifampicin
rpoC	766996	c.3627C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767002	c.3633G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767023	c.3654C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767038	c.3669G>A	synonymous_variant	1.0	rifampicin
rpoC	767098	c.3729T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767104	c.3735C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767119	c.3750A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767155	c.3786C>G	synonymous_variant	1.0	rifampicin
rpoC	767161	c.3792C>T	synonymous_variant	1.0	rifampicin
rpoC	767162	p.Asn1265Pro	missense_variant	1.0	rifampicin
rpoC	767167	c.3798C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767180	p.Ala1271Gln	missense_variant	1.0	rifampicin
rpoC	767197	c.3828G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767221	c.3852C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767230	c.3861G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767233	c.3864T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767263	c.3894T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767264	p.Ala1299Gln	missense_variant	1.0	rifampicin
rpoC	767278	c.3909T>C	synonymous_variant	1.0	rifampicin
mmpL5	775796	c.2683_2685delTTTinsAG	frameshift_variant&stop_gained	0.82	clofazimine	Uncertain significance
mmpL5	775796	c.2683_2685delTTTinsAG	frameshift_variant&stop_gained	0.82	bedaquiline	Uncertain significance
mmpL5	775802	p.Met893Ile	missense_variant	0.5	clofazimine
mmpL5	775802	p.Met893Ile	missense_variant	0.5	bedaquiline
mmpL5	775817	c.2664T>C	synonymous_variant	0.87	clofazimine	Not assoc w R - Interim
mmpL5	775817	c.2664T>C	synonymous_variant	0.87	bedaquiline	Not assoc w R - Interim
mmpL5	775826	c.2655G>C	synonymous_variant	0.38	clofazimine
mmpL5	775826	c.2655G>C	synonymous_variant	0.38	bedaquiline
mmpL5	775829	c.2652C>G	synonymous_variant	0.72	clofazimine
mmpL5	775829	c.2652C>G	synonymous_variant	0.72	bedaquiline
mmpL5	775832	c.2649C>G	synonymous_variant	0.72	clofazimine
mmpL5	775832	c.2649C>G	synonymous_variant	0.72	bedaquiline
mmpL5	775835	c.2646C>G	synonymous_variant	0.74	clofazimine
mmpL5	775835	c.2646C>G	synonymous_variant	0.74	bedaquiline
mmpL5	775847	c.2634G>C	synonymous_variant	0.54	clofazimine
mmpL5	775847	c.2634G>C	synonymous_variant	0.54	bedaquiline
mmpL5	775856	c.2625T>C	synonymous_variant	0.9	clofazimine
mmpL5	775856	c.2625T>C	synonymous_variant	0.9	bedaquiline
mmpL5	775865	c.2616T>G	synonymous_variant	0.91	clofazimine
mmpL5	775865	c.2616T>G	synonymous_variant	0.91	bedaquiline
mmpL5	775886	c.2595A>C	synonymous_variant	0.95	clofazimine
mmpL5	775886	c.2595A>C	synonymous_variant	0.95	bedaquiline
mmpL5	775895	c.2584_2586delATCinsCG	frameshift_variant&missense_variant	0.5	clofazimine	Uncertain significance
mmpL5	775895	c.2584_2586delATCinsCG	frameshift_variant&missense_variant	0.5	bedaquiline	Uncertain significance
mmpL5	775898	c.2583G>A	synonymous_variant	0.5	clofazimine
mmpL5	775898	c.2583G>A	synonymous_variant	0.5	bedaquiline
mmpL5	775904	c.2577G>A	synonymous_variant	0.61	clofazimine
mmpL5	775904	c.2577G>A	synonymous_variant	0.61	bedaquiline
mmpL5	775907	c.2572_2574delCTCinsTG	frameshift_variant&synonymous_variant	0.61	clofazimine	Uncertain significance
mmpL5	775907	c.2572_2574delCTCinsTG	frameshift_variant&synonymous_variant	0.61	bedaquiline	Uncertain significance
mmpL5	775910	c.2571G>C	synonymous_variant	0.51	clofazimine
mmpL5	775910	c.2571G>C	synonymous_variant	0.51	bedaquiline
mmpL5	775913	c.2566_2568delGCCinsTA	frameshift_variant&missense_variant	0.6	clofazimine	Uncertain significance
mmpL5	775913	c.2566_2568delGCCinsTA	frameshift_variant&missense_variant	0.6	bedaquiline	Uncertain significance
mmpL5	775916	c.2565T>G	synonymous_variant	0.96	clofazimine
mmpL5	775916	c.2565T>G	synonymous_variant	0.96	bedaquiline
mmpL5	775939	p.Ala848Ser	missense_variant	0.47	clofazimine
mmpL5	775939	p.Ala848Ser	missense_variant	0.47	bedaquiline
mmpL5	775943	c.2538C>G	synonymous_variant	0.65	clofazimine
mmpL5	775943	c.2538C>G	synonymous_variant	0.65	bedaquiline
mmpL5	775946	c.2535C>G	synonymous_variant	0.78	clofazimine
mmpL5	775946	c.2535C>G	synonymous_variant	0.78	bedaquiline
mmpL5	775951	c.2530C>T	synonymous_variant	0.86	clofazimine
mmpL5	775951	c.2530C>T	synonymous_variant	0.86	bedaquiline
mmpL5	775955	p.Ile842Met	missense_variant	0.31	clofazimine
mmpL5	775955	p.Ile842Met	missense_variant	0.31	bedaquiline
mmpL5	775961	c.2520C>G	synonymous_variant	0.41	clofazimine
mmpL5	775961	c.2520C>G	synonymous_variant	0.41	bedaquiline
mmpL5	775966	p.Ala839Ser	missense_variant	0.89	clofazimine
mmpL5	775966	p.Ala839Ser	missense_variant	0.89	bedaquiline
mmpL5	775975	p.Leu836Met	missense_variant	1.0	clofazimine
mmpL5	775975	p.Leu836Met	missense_variant	1.0	bedaquiline
mmpL5	775981	p.Leu834Met	missense_variant	1.0	clofazimine
mmpL5	775981	p.Leu834Met	missense_variant	1.0	bedaquiline
mmpL5	775991	c.2488_2490delGAGinsAC	frameshift_variant&missense_variant	0.62	clofazimine	Uncertain significance
mmpL5	775991	c.2488_2490delGAGinsAC	frameshift_variant&missense_variant	0.62	bedaquiline	Uncertain significance
mmpL5	775997	c.2484T>G	synonymous_variant	1.0	clofazimine
mmpL5	775997	c.2484T>G	synonymous_variant	1.0	bedaquiline
mmpL5	776000	c.2481G>C	synonymous_variant	0.61	clofazimine
mmpL5	776000	c.2481G>C	synonymous_variant	0.61	bedaquiline
mmpL5	776009	c.2472A>G	synonymous_variant	0.9	clofazimine
mmpL5	776009	c.2472A>G	synonymous_variant	0.9	bedaquiline
mmpL5	776015	c.2464_2466delATCinsTG	frameshift_variant&missense_variant	0.39	clofazimine	Uncertain significance
mmpL5	776015	c.2464_2466delATCinsTG	frameshift_variant&missense_variant	0.39	bedaquiline	Uncertain significance
mmpL5	776018	c.2461_2463delCTGinsTC	frameshift_variant&synonymous_variant	0.56	clofazimine	Uncertain significance
mmpL5	776018	c.2461_2463delCTGinsTC	frameshift_variant&synonymous_variant	0.56	bedaquiline	Uncertain significance
mmpL5	776021	c.2458_2460delGTGinsAC	frameshift_variant&missense_variant	0.55	clofazimine	Uncertain significance
mmpL5	776021	c.2458_2460delGTGinsAC	frameshift_variant&missense_variant	0.55	bedaquiline	Uncertain significance
mmpL5	776030	c.2451G>C	synonymous_variant	0.96	clofazimine
mmpL5	776030	c.2451G>C	synonymous_variant	0.96	bedaquiline
mmpL5	776039	c.2442C>T	synonymous_variant	0.35	clofazimine
mmpL5	776039	c.2442C>T	synonymous_variant	0.35	bedaquiline
mmpL5	776053	p.Leu810Val	missense_variant	0.66	clofazimine
mmpL5	776053	p.Leu810Val	missense_variant	0.66	bedaquiline
mmpL5	776060	c.2421C>G	synonymous_variant	0.91	clofazimine
mmpL5	776060	c.2421C>G	synonymous_variant	0.91	bedaquiline
mmpL5	776072	c.2409C>G	synonymous_variant	0.71	clofazimine
mmpL5	776072	c.2409C>G	synonymous_variant	0.71	bedaquiline
mmpL5	776075	c.2406C>G	synonymous_variant	0.69	clofazimine
mmpL5	776075	c.2406C>G	synonymous_variant	0.69	bedaquiline
mmpL5	776078	c.2403C>G	synonymous_variant	0.93	clofazimine
mmpL5	776078	c.2403C>G	synonymous_variant	0.93	bedaquiline
mmpL5	776081	c.2400G>C	synonymous_variant	0.6	clofazimine
mmpL5	776081	c.2400G>C	synonymous_variant	0.6	bedaquiline
mmpL5	776087	c.2394C>G	synonymous_variant	0.93	clofazimine
mmpL5	776087	c.2394C>G	synonymous_variant	0.93	bedaquiline
mmpL5	776093	c.2388C>A	synonymous_variant	0.67	clofazimine
mmpL5	776093	c.2388C>A	synonymous_variant	0.67	bedaquiline
mmpL5	776100	p.Thr794Ile	missense_variant	1.0	clofazimine	Not assoc w R
mmpL5	776100	p.Thr794Ile	missense_variant	1.0	bedaquiline	Not assoc w R - Interim
rpsL	781592	c.33T>G	synonymous_variant	0.86	streptomycin
rpsL	781595	c.36T>C	synonymous_variant	0.93	streptomycin
rpsL	781598	c.39G>T	synonymous_variant	0.86	streptomycin
rpsL	781605	p.Ile16Pro	missense_variant	0.86	streptomycin
rpsL	781608	c.49_51delAGTinsGC	frameshift_variant&missense_variant	0.86	streptomycin	Uncertain significance
rpsL	781616	c.57C>G	synonymous_variant	0.86	streptomycin
rpsL	781617	p.Lys20Arg	missense_variant	0.86	streptomycin
rpsL	781620	p.Thr21Val	missense_variant	0.86	streptomycin
rpsL	781625	c.66G>C	synonymous_variant	0.86	streptomycin
rpsL	781628	c.69T>A	synonymous_variant	0.87	streptomycin
rpsL	781631	c.72G>C	synonymous_variant	0.88	streptomycin
rpsL	781649	c.90T>C	synonymous_variant	0.93	streptomycin
rpsL	781652	c.93T>C	synonymous_variant	0.93	streptomycin
rpsL	781655	c.96T>C	synonymous_variant	0.93	streptomycin
rpsL	781658	c.99A>G	synonymous_variant	0.93	streptomycin
rpsL	781682	c.123T>C	synonymous_variant	0.98	streptomycin
rpsL	781709	c.150G>C	synonymous_variant	0.98	streptomycin	Not assoc w R - Interim
rpsL	781715	c.156T>C	synonymous_variant	0.98	streptomycin
rpsL	781718	c.159C>A	synonymous_variant	0.98	streptomycin
rpsL	781728	c.169T>C	synonymous_variant	0.97	streptomycin
rpsL	781733	c.174G>C	synonymous_variant	0.97	streptomycin
rpsL	781735	p.Ser59Thr	missense_variant	0.97	streptomycin
rpsL	781751	c.192G>C	synonymous_variant	0.98	streptomycin
rpsL	781754	c.195G>C	synonymous_variant	0.98	streptomycin
rpsL	781760	c.201T>C	synonymous_variant	0.96	streptomycin
rpsL	781763	c.204C>G	synonymous_variant	0.96	streptomycin
rpsL	781793	c.234G>C	synonymous_variant	0.97	streptomycin
rpsL	781808	c.249C>T	synonymous_variant	0.98	streptomycin
rpsL	781814	c.255C>T	synonymous_variant	0.98	streptomycin
rpsL	781817	c.258G>T	synonymous_variant	0.97	streptomycin
rpsL	781832	c.273T>G	synonymous_variant	0.98	streptomycin
rpsL	781859	c.300T>C	synonymous_variant	0.98	streptomycin	Not assoc w R - Interim
rpsL	781865	c.306G>C	synonymous_variant	0.98	streptomycin
rpsL	781868	c.309T>C	synonymous_variant	0.98	streptomycin
rpsL	781871	c.312G>C	synonymous_variant	0.98	streptomycin
rpsL	781880	c.321C>G	synonymous_variant	0.98	streptomycin
rpsL	781892	c.333A>G	synonymous_variant	0.98	streptomycin
rpsL	781904	c.345C>T	synonymous_variant	1.0	streptomycin	Not assoc w R - Interim
rpsL	781907	c.348T>C	synonymous_variant	1.0	streptomycin
rpsL	781916	c.357T>C	synonymous_variant	1.0	streptomycin
rpsL	781929	p.Gly124Ser	missense_variant	1.0	streptomycin	Uncertain significance
rplC	800516	c.-293G>C	upstream_gene_variant	0.93	linezolid
rplC	800531	c.-278T>C	upstream_gene_variant	0.94	linezolid
rplC	800537	c.-272C>G	upstream_gene_variant	0.95	linezolid
rplC	800540	c.-269T>C	upstream_gene_variant	0.95	linezolid
rplC	800546	c.-263T>C	upstream_gene_variant	0.97	linezolid
rplC	800567	c.-242A>G	upstream_gene_variant	0.95	linezolid
rplC	800570	c.-239C>G	upstream_gene_variant	0.95	linezolid
rplC	800574	c.-235_-234delGTinsAC	upstream_gene_variant	0.95	linezolid
rplC	800579	c.-230C>G	upstream_gene_variant	0.95	linezolid
rplC	800582	c.-227C>G	upstream_gene_variant	0.95	linezolid
rplC	800585	c.-224T>C	upstream_gene_variant	0.95	linezolid
rplC	800594	c.-215C>G	upstream_gene_variant	0.95	linezolid
rplC	800597	c.-212A>C	upstream_gene_variant	0.95	linezolid
rplC	800600	c.-209G>C	upstream_gene_variant	0.95	linezolid
rplC	800612	c.-197A>G	upstream_gene_variant	0.96	linezolid
rplC	800618	c.-191T>C	upstream_gene_variant	0.98	linezolid
rplC	800633	c.-176T>C	upstream_gene_variant	0.98	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	0.98	linezolid
rplC	800693	c.-116A>C	upstream_gene_variant	0.97	linezolid
rplC	800702	c.-107G>A	upstream_gene_variant	0.97	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	0.97	linezolid
rplC	800715	c.-94A>C	upstream_gene_variant	0.98	linezolid
rplC	800720	c.-89T>C	upstream_gene_variant	0.98	linezolid
rplC	800723	c.-86C>G	upstream_gene_variant	0.98	linezolid
rplC	800735	c.-74C>G	upstream_gene_variant	0.98	linezolid
rplC	800738	c.-71T>C	upstream_gene_variant	0.98	linezolid
rplC	800747	c.-62C>G	upstream_gene_variant	0.98	linezolid
rplC	800762	c.-47T>G	upstream_gene_variant	0.98	linezolid
rplC	800774	c.-35C>T	upstream_gene_variant	0.98	linezolid
rplC	800799	c.-10_-8delGGAinsC	upstream_gene_variant	0.94	linezolid
rplC	800807	c.-2C>A	upstream_gene_variant	0.94	linezolid
rplC	800814	c.6A>T	synonymous_variant	0.94	linezolid
rplC	800815	c.7_9delCGAinsAG	frameshift_variant&synonymous_variant	0.94	linezolid
rplC	800829	c.21C>G	synonymous_variant	0.95	linezolid
rplC	800832	c.24T>C	synonymous_variant	0.96	linezolid
rplC	800844	c.36T>C	synonymous_variant	0.96	linezolid
rplC	800856	c.48A>G	synonymous_variant	0.98	linezolid
rplC	800865	c.57A>G	synonymous_variant	0.98	linezolid
rplC	800867	p.Ser20Asn	missense_variant	0.98	linezolid
rplC	800874	c.66A>G	synonymous_variant	0.98	linezolid
rplC	800877	c.69A>C	synonymous_variant	0.98	linezolid
rplC	800880	c.72A>G	synonymous_variant	0.98	linezolid
rplC	800889	c.81C>G	synonymous_variant	0.98	linezolid
rplC	800892	c.84G>C	synonymous_variant	0.98	linezolid
rplC	800904	c.96G>C	synonymous_variant	1.0	linezolid
rplC	800913	c.105G>C	synonymous_variant	0.98	linezolid
rplC	800916	c.108A>C	synonymous_variant	0.98	linezolid
rplC	800919	c.111C>G	synonymous_variant	0.98	linezolid
rplC	800931	c.123G>T	synonymous_variant	0.98	linezolid
rplC	800937	c.129A>G	synonymous_variant	0.97	linezolid
rplC	800946	c.138T>C	synonymous_variant	1.0	linezolid
rplC	800949	c.141T>C	synonymous_variant	1.0	linezolid
rplC	800970	c.162T>C	synonymous_variant	1.0	linezolid	Not assoc w R - Interim
rplC	800981	p.Ser58Asn	missense_variant	1.0	linezolid
rplC	800985	c.177A>G	synonymous_variant	1.0	linezolid
rplC	800994	c.186C>G	synonymous_variant	1.0	linezolid
rplC	801008	p.Thr67Lys	missense_variant	1.0	linezolid
rplC	801019	p.Thr71Glu	missense_variant	1.0	linezolid
rplC	801027	c.219C>G	synonymous_variant	1.0	linezolid
rplC	801117	c.309G>C	synonymous_variant	1.0	linezolid
rplC	801127	p.Ala107Thr	missense_variant	1.0	linezolid
rplC	801132	c.324T>C	synonymous_variant	1.0	linezolid
rplC	801156	c.348T>C	synonymous_variant	1.0	linezolid
rplC	801160	c.352_353delTCinsAG	synonymous_variant	1.0	linezolid
rplC	801171	c.363A>G	synonymous_variant	1.0	linezolid
rplC	801174	c.366T>C	synonymous_variant	0.98	linezolid
rplC	801180	c.372C>G	synonymous_variant	0.98	linezolid
rplC	801195	c.387G>C	synonymous_variant	0.98	linezolid
rplC	801201	c.393C>T	synonymous_variant	0.96	linezolid
rplC	801210	c.402T>C	synonymous_variant	0.98	linezolid
rplC	801222	c.414T>C	synonymous_variant	0.98	linezolid
rplC	801228	c.420T>C	synonymous_variant	0.98	linezolid
rplC	801229	p.Ala141Thr	missense_variant	0.98	linezolid
rplC	801252	c.444G>C	synonymous_variant	0.98	linezolid
rplC	801255	c.447C>T	synonymous_variant	0.98	linezolid
rplC	801267	c.459A>C	synonymous_variant	0.98	linezolid
rplC	801270	c.462T>C	synonymous_variant	0.98	linezolid
rplC	801273	c.465C>G	synonymous_variant	0.98	linezolid
rplC	801281	p.Ala158Gly	missense_variant	0.98	linezolid
rplC	801303	c.495G>C	synonymous_variant	0.98	linezolid
rplC	801309	c.501C>G	synonymous_variant	0.95	linezolid
rplC	801312	c.504G>C	synonymous_variant	0.94	linezolid
rplC	801324	c.516T>C	synonymous_variant	1.0	linezolid
rplC	801330	c.522G>C	synonymous_variant	0.95	linezolid
rplC	801331	c.523_525delGTGinsAC	frameshift_variant&missense_variant	0.95	linezolid
rplC	801337	p.Val177Thr	missense_variant	0.95	linezolid
rplC	801341	p.Leu178Gln	missense_variant	0.95	linezolid
rplC	801348	c.540T>G	synonymous_variant	0.95	linezolid
rplC	801357	c.549T>C	synonymous_variant	0.9	linezolid
rplC	801385	c.577C>T	synonymous_variant	0.82	linezolid
fbiC	1303497	c.567G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303506	c.576C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303509	c.579G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303512	c.582T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303531	p.Met201Leu	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303545	c.615A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303551	c.621G>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303971	c.1041T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303977	c.1047C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303980	c.1050G>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303995	c.1065C>T	synonymous_variant	1.0	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1303998	c.1068T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304001	c.1071C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304004	c.1074A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304008	c.1078T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304013	c.1083G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304019	c.1089C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304022	c.1092T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304031	c.1101C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304040	c.1110C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304048	p.Ala373Gly	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304092	p.Met388Leu	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304106	c.1176G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304118	c.1188C>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304127	c.1197A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304133	c.1203G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304571	c.1641G>C	synonymous_variant	0.93	clofazimine
					pretomanid
					delamanid
fbiC	1304577	c.1647C>T	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fbiC	1304580	c.1650T>C	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fbiC	1304607	c.1677C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304610	c.1680C>G	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiC	1304613	c.1683T>A	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiC	1304625	c.1695C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304631	c.1701C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304640	c.1710A>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304652	c.1722C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304655	c.1725C>T	synonymous_variant	0.95	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304658	c.1728C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304670	c.1740G>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304675	p.Gly582Asp	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304694	c.1764A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304703	c.1773C>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304709	c.1779C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304715	c.1785G>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304724	c.1794A>G	synonymous_variant	0.96	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304727	c.1797A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304748	c.1818T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304751	c.1821C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304754	c.1824G>A	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304757	c.1827A>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304763	c.1833C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304769	c.1839C>T	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304772	c.1842C>T	synonymous_variant	0.97	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304778	c.1848T>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304784	c.1854T>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304787	c.1857T>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304808	c.1878C>A	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304811	c.1881C>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304817	c.1887T>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304826	c.1896G>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304829	c.1899T>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304832	c.1902C>G	synonymous_variant	0.94	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304835	c.1905G>A	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304856	c.1926C>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304868	c.1938G>A	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304871	c.1941G>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304872	c.1942_1944delAGCinsTCG	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304877	c.1947T>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304887	c.1957C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304894	p.Gly655Ala	missense_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304901	c.1971C>G	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304910	c.1980G>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304916	c.1986T>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304922	c.1992C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304925	c.1995G>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304928	c.1998T>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304931	c.2001C>G	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304937	c.2007G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304940	c.2010A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304946	c.2016G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304958	c.2028T>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304967	c.2037G>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
sigE	1364667	c.255T>C	synonymous_variant	0.91	pyrazinamide
sigE	1364676	c.264C>G	synonymous_variant	0.92	pyrazinamide
sigE	1364703	c.291G>C	synonymous_variant	0.95	pyrazinamide
sigE	1364709	c.297T>C	synonymous_variant	0.95	pyrazinamide
sigE	1364712	c.300T>C	synonymous_variant	0.96	pyrazinamide
sigE	1364718	c.306C>T	synonymous_variant	0.96	pyrazinamide
sigE	1364727	c.315C>T	synonymous_variant	0.96	pyrazinamide
sigE	1364736	c.324T>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
sigE	1364742	c.330A>G	synonymous_variant	0.97	pyrazinamide
sigE	1364763	c.351T>C	synonymous_variant	0.96	pyrazinamide
sigE	1364767	c.355_357delAGGinsCC	frameshift_variant&missense_variant	0.96	pyrazinamide	Uncertain significance
sigE	1364772	c.360G>C	synonymous_variant	0.96	pyrazinamide
sigE	1364778	c.366G>C	synonymous_variant	0.92	pyrazinamide
sigE	1364782	c.370_372delGTCinsCG	frameshift_variant&missense_variant	0.92	pyrazinamide	Uncertain significance
sigE	1364790	c.378T>C	synonymous_variant	0.92	pyrazinamide
sigE	1364799	c.387G>C	synonymous_variant	0.93	pyrazinamide
sigE	1364805	c.393C>G	synonymous_variant	0.97	pyrazinamide
sigE	1364811	c.399A>G	synonymous_variant	0.93	pyrazinamide
sigE	1364818	c.406_408delCTAinsTG	frameshift_variant&stop_gained	0.93	pyrazinamide	Uncertain significance
sigE	1364832	c.420C>G	synonymous_variant	0.93	pyrazinamide
sigE	1364835	c.423C>G	synonymous_variant	0.93	pyrazinamide
sigE	1364839	c.427T>C	synonymous_variant	0.93	pyrazinamide
sigE	1364847	c.435G>C	synonymous_variant	0.92	pyrazinamide
sigE	1364856	c.444C>G	synonymous_variant	0.91	pyrazinamide
sigE	1364862	c.450C>G	synonymous_variant	0.9	pyrazinamide
sigE	1364868	c.456T>C	synonymous_variant	0.88	pyrazinamide
sigE	1364877	c.465G>A	synonymous_variant	0.88	pyrazinamide
sigE	1364883	c.471G>A	synonymous_variant	0.92	pyrazinamide
sigE	1364886	c.474G>A	synonymous_variant	0.9	pyrazinamide
sigE	1364887	c.475_477delTTAinsCG	frameshift_variant&missense_variant	0.9	pyrazinamide	Uncertain significance
sigE	1364892	c.480C>G	synonymous_variant	0.92	pyrazinamide
sigE	1364904	p.Asp164Glu	missense_variant	0.95	pyrazinamide
sigE	1364919	c.507T>C	synonymous_variant	0.95	pyrazinamide
sigE	1364920	p.Glu170Ser	missense_variant	0.95	pyrazinamide
sigE	1364950	c.538_540delGCAinsTG	frameshift_variant&stop_gained	1.0	pyrazinamide	Uncertain significance
sigE	1364956	c.544C>T	synonymous_variant	1.0	pyrazinamide
sigE	1364961	c.549A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
sigE	1364964	c.552T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
sigE	1364976	c.564T>C	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
sigE	1364979	c.567C>G	synonymous_variant	0.93	pyrazinamide
sigE	1364980	c.568_570delTTGinsCC	frameshift_variant&missense_variant	0.93	pyrazinamide	Uncertain significance
sigE	1364984	p.Ala191Asp	missense_variant	0.93	pyrazinamide
sigE	1364994	c.582G>C	synonymous_variant	0.93	pyrazinamide
sigE	1365000	c.588G>A	synonymous_variant	0.93	pyrazinamide	Not assoc w R - Interim
sigE	1365006	c.594T>C	synonymous_variant	0.93	pyrazinamide
sigE	1365015	c.603G>C	synonymous_variant	0.93	pyrazinamide
sigE	1365024	c.612T>C	synonymous_variant	0.93	pyrazinamide
sigE	1365042	c.630G>C	synonymous_variant	0.92	pyrazinamide
rrs	1471923	n.78T>C	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471925	n.80T>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471932	n.87A>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471934	n.89A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471936	n.91A>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471986	n.141C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472019	n.174G>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472022	n.178_181delGGAC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472030	n.185delGinsCCTGCT	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472033	n.188A>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472034	n.189T>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472040	n.195delTinsGC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472043	n.198T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472048	n.203T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472053	n.211_212delGC	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472061	n.216A>T	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472279	n.434T>C	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472286	n.441C>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472287	n.442C>T	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472297	n.453_454delGT	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472303	n.458_470delGGTTCTCTCGGATinsTGAGG	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472327	n.482G>A	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472328	n.483G>C	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin
					capreomycin
					amikacin
rrs	1472446	n.601T>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472452	n.607G>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472464	n.619A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472489	n.644A>G	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472973	n.1128A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473110	n.1265T>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473111	n.1266A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473123	n.1278delAinsTC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473276	n.1431A>G	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473289	n.1444T>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473290	n.1445_1446insAA	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473301	n.1456T>C	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1473696	n.39T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473696	n.39T>C	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473697	n.40C>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473697	n.40C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473699	n.42A>G	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473699	n.42A>G	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473743	n.86C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1473743	n.86C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473811	n.154C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473811	n.154C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473813	n.156C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473813	n.156C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473814	n.157A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473814	n.157A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473815	n.158T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473815	n.158T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473816	n.159C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473816	n.159C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473822	n.165A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473822	n.165A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473828	n.171G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473828	n.171G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473829	n.172G>C	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473829	n.172G>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473830	n.173T>G	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1473830	n.173T>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473831	n.174G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473831	n.174G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473833	n.176G>T	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1473833	n.176G>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473836	n.179A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473836	n.179A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474202	n.545T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474202	n.545T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474282	n.625G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474282	n.625G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474287	n.630delTinsCCC	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474287	n.630delTinsCCC	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474293	n.637_644delCCTCTCCG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474293	n.637_644delCCTCTCCG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474303	n.646A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474303	n.646A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474306	n.649A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474306	n.649A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474308	n.653_654delTG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474308	n.653_654delTG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474350	n.693G>C	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1474350	n.693G>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474351	n.694G>C	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474351	n.694G>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474374	n.717T>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474374	n.717T>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474413	n.756_757delACinsTAT	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474413	n.756_757delACinsTAT	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474418	n.761C>A	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474418	n.761C>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474421	n.764_767delGCGCinsA	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474421	n.764_767delGCGCinsA	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474437	n.780_781delGAinsTTGGT	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474437	n.780_781delGAinsTTGGT	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474439	n.782A>G	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474439	n.782A>G	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474446	n.789C>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474446	n.789C>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474452	n.795C>G	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1474452	n.795C>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474629	n.972G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474629	n.972G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474639	n.982G>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474639	n.982G>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474710	n.1053delTinsACAA	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474710	n.1053delTinsACAA	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474720	n.1063C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474720	n.1063C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475088	n.1431A>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475088	n.1431A>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475202	n.1545G>A	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1475202	n.1545G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475333	n.1676T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475333	n.1676T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475379	n.1722G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475379	n.1722G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475381	n.1724G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475381	n.1724G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475382	n.1725A>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475382	n.1725A>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475393	n.1737_1738insGATG	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475393	n.1737_1738insGATG	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475397	n.1741_1745delCTCAC	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475397	n.1741_1745delCTCAC	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475404	n.1747A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475404	n.1747A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475405	n.1748A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475405	n.1748A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475430	n.1773T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475430	n.1773T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475458	n.1801C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475458	n.1801C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475460	n.1803A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475460	n.1803A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475480	n.1823A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475480	n.1823A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475532	n.1875A>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475532	n.1875A>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475603	n.1946G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475603	n.1946G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1475606	n.1949T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475606	n.1949T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475613	n.1956A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475613	n.1956A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475615	n.1958C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475615	n.1958C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475626	n.1969T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475626	n.1969T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475627	n.1970G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475627	n.1970G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475628	n.1971G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475628	n.1971G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475629	n.1972G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475629	n.1972G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475643	n.1986C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475643	n.1986C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475707	n.2050T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475707	n.2050T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475991	n.2334T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475991	n.2334T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476033	n.2376T>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476033	n.2376T>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476034	n.2377C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476034	n.2377C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476035	n.2378G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476035	n.2378G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476045	n.2388G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476045	n.2388G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476046	n.2389G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476046	n.2389G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476058	n.2401T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476058	n.2401T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476165	n.2508T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476165	n.2508T>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476251	n.2594T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476251	n.2594T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476252	n.2595T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476252	n.2595T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476256	n.2599A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476256	n.2599A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476529	n.2872A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476529	n.2872A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476679	n.3022T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476679	n.3022T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476692	n.3035T>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476692	n.3035T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476740	n.3083G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476740	n.3083G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476741	n.3084G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476741	n.3084G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476743	n.3086A>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476743	n.3086A>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476744	n.3087G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476744	n.3087G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476746	n.3089T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476746	n.3089T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476757	n.3100T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476757	n.3100T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	1.0	linezolid
inhA	1673667	c.-535A>G	upstream_gene_variant	0.73	ethionamide
inhA	1673667	c.-535A>G	upstream_gene_variant	0.73	isoniazid
inhA	1673679	c.-523T>C	upstream_gene_variant	0.73	ethionamide	Uncertain significance
inhA	1673679	c.-523T>C	upstream_gene_variant	0.73	isoniazid	Uncertain significance
inhA	1673682	c.-520G>C	upstream_gene_variant	0.75	ethionamide	Uncertain significance
inhA	1673682	c.-520G>C	upstream_gene_variant	0.75	isoniazid	Uncertain significance
inhA	1673692	c.-510C>G	upstream_gene_variant	0.77	ethionamide	Uncertain significance
inhA	1673692	c.-510C>G	upstream_gene_variant	0.77	isoniazid	Uncertain significance
inhA	1673697	c.-505G>C	upstream_gene_variant	0.77	ethionamide
inhA	1673697	c.-505G>C	upstream_gene_variant	0.77	isoniazid
fabG1	1673710	c.271_273delCTAinsAC	frameshift_variant&missense_variant	0.77	ethionamide
fabG1	1673710	c.271_273delCTAinsAC	frameshift_variant&missense_variant	0.77	isoniazid
fabG1	1673716	p.Ala93Lys	missense_variant	0.77	ethionamide
fabG1	1673716	p.Ala93Lys	missense_variant	0.77	isoniazid
inhA	1673724	c.-478A>G	upstream_gene_variant	0.77	ethionamide
inhA	1673724	c.-478A>G	upstream_gene_variant	0.77	isoniazid
inhA	1673727	c.-475C>T	upstream_gene_variant	0.77	ethionamide
inhA	1673727	c.-475C>T	upstream_gene_variant	0.77	isoniazid	Uncertain significance
fabG1	1673733	p.Met98Ile	missense_variant	0.77	ethionamide
fabG1	1673733	p.Met98Ile	missense_variant	0.77	isoniazid
inhA	1673736	c.-466G>A	upstream_gene_variant	0.77	ethionamide
inhA	1673736	c.-466G>A	upstream_gene_variant	0.77	isoniazid
inhA	1673748	c.-454A>G	upstream_gene_variant	0.91	ethionamide
inhA	1673748	c.-454A>G	upstream_gene_variant	0.91	isoniazid
fabG1	1673749	p.Lys104Arg	missense_variant	0.91	ethionamide
fabG1	1673749	p.Lys104Arg	missense_variant	0.91	isoniazid
fabG1	1673758	p.Lys107Glu	missense_variant	0.91	ethionamide
fabG1	1673758	p.Lys107Glu	missense_variant	0.91	isoniazid
inhA	1673784	c.-418G>C	upstream_gene_variant	0.95	ethionamide
inhA	1673784	c.-418G>C	upstream_gene_variant	0.95	isoniazid
inhA	1673799	c.-403T>C	upstream_gene_variant	1.0	ethionamide
inhA	1673799	c.-403T>C	upstream_gene_variant	1.0	isoniazid
inhA	1673802	c.-400A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673802	c.-400A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673805	c.-397G>C	upstream_gene_variant	1.0	ethionamide
inhA	1673805	c.-397G>C	upstream_gene_variant	1.0	isoniazid
inhA	1673808	c.-394A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673808	c.-394A>G	upstream_gene_variant	1.0	isoniazid
inhA	1674471	c.270G>C	synonymous_variant	0.87	ethionamide
inhA	1674471	c.270G>C	synonymous_variant	0.87	isoniazid
inhA	1674474	c.273G>C	synonymous_variant	0.87	ethionamide
inhA	1674474	c.273G>C	synonymous_variant	0.87	isoniazid
inhA	1674486	c.285T>C	synonymous_variant	0.87	ethionamide
inhA	1674486	c.285T>C	synonymous_variant	0.87	isoniazid
inhA	1674502	c.301_303delACCinsTG	frameshift_variant&missense_variant	0.87	ethionamide
inhA	1674502	c.301_303delACCinsTG	frameshift_variant&missense_variant	0.87	isoniazid
inhA	1674507	c.306G>C	synonymous_variant	0.88	ethionamide
inhA	1674507	c.306G>C	synonymous_variant	0.88	isoniazid
inhA	1674513	c.312C>G	synonymous_variant	0.89	ethionamide
inhA	1674513	c.312C>G	synonymous_variant	0.89	isoniazid
inhA	1674534	c.333G>A	synonymous_variant	0.91	ethionamide
inhA	1674534	c.333G>A	synonymous_variant	0.91	isoniazid
inhA	1674542	p.Ala114Glu	missense_variant	0.95	ethionamide
inhA	1674542	p.Ala114Glu	missense_variant	0.95	isoniazid
inhA	1674546	c.345T>C	synonymous_variant	0.95	ethionamide
inhA	1674546	c.345T>C	synonymous_variant	0.95	isoniazid
inhA	1674549	c.348G>C	synonymous_variant	0.95	ethionamide
inhA	1674549	c.348G>C	synonymous_variant	0.95	isoniazid
inhA	1674550	p.Ser117Ala	missense_variant	0.95	ethionamide
inhA	1674550	p.Ser117Ala	missense_variant	0.95	isoniazid
inhA	1674561	c.360C>T	synonymous_variant	0.96	ethionamide
inhA	1674561	c.360C>T	synonymous_variant	0.96	isoniazid
inhA	1674576	c.375T>C	synonymous_variant	0.94	ethionamide
inhA	1674576	c.375T>C	synonymous_variant	0.94	isoniazid
inhA	1674579	c.378G>C	synonymous_variant	0.94	ethionamide
inhA	1674579	c.378G>C	synonymous_variant	0.94	isoniazid
inhA	1674582	c.381T>C	synonymous_variant	0.94	ethionamide
inhA	1674582	c.381T>C	synonymous_variant	0.94	isoniazid
inhA	1674585	c.384T>C	synonymous_variant	0.94	ethionamide
inhA	1674585	c.384T>C	synonymous_variant	0.94	isoniazid
inhA	1674589	p.Met130Leu	missense_variant	0.94	ethionamide
inhA	1674589	p.Met130Leu	missense_variant	0.94	isoniazid
inhA	1674601	p.Leu134Thr	missense_variant	0.94	ethionamide
inhA	1674601	p.Leu134Thr	missense_variant	0.94	isoniazid
inhA	1674636	c.435C>G	synonymous_variant	1.0	ethionamide
inhA	1674636	c.435C>G	synonymous_variant	1.0	isoniazid
inhA	1674654	c.453G>C	synonymous_variant	1.0	ethionamide
inhA	1674654	c.453G>C	synonymous_variant	1.0	isoniazid
inhA	1674656	p.Ser152Thr	missense_variant	1.0	ethionamide
inhA	1674656	p.Ser152Thr	missense_variant	1.0	isoniazid
inhA	1674669	c.468G>C	synonymous_variant	1.0	ethionamide
inhA	1674669	c.468G>C	synonymous_variant	1.0	isoniazid
inhA	1674672	c.471C>G	synonymous_variant	1.0	ethionamide
inhA	1674672	c.471C>G	synonymous_variant	1.0	isoniazid
inhA	1674690	c.489C>G	synonymous_variant	1.0	ethionamide
inhA	1674690	c.489C>G	synonymous_variant	1.0	isoniazid
inhA	1674703	c.502T>C	synonymous_variant	1.0	ethionamide
inhA	1674703	c.502T>C	synonymous_variant	1.0	isoniazid
inhA	1674711	c.510G>C	synonymous_variant	1.0	ethionamide
inhA	1674711	c.510G>C	synonymous_variant	1.0	isoniazid
inhA	1674718	c.517A>C	synonymous_variant	1.0	ethionamide
inhA	1674718	c.517A>C	synonymous_variant	1.0	isoniazid
inhA	1674726	c.525G>C	synonymous_variant	1.0	ethionamide
inhA	1674726	c.525G>C	synonymous_variant	1.0	isoniazid
inhA	1674737	p.Ala179Val	missense_variant	1.0	ethionamide
inhA	1674737	p.Ala179Val	missense_variant	1.0	isoniazid
inhA	1674741	c.540C>A	synonymous_variant	1.0	ethionamide
inhA	1674741	c.540C>A	synonymous_variant	1.0	isoniazid
inhA	1674742	p.Lys181Pro	missense_variant	1.0	ethionamide
inhA	1674742	p.Lys181Pro	missense_variant	1.0	isoniazid
inhA	1674745	p.Tyr182His	missense_variant	1.0	ethionamide	Uncertain significance
inhA	1674745	p.Tyr182His	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674750	c.549T>G	synonymous_variant	1.0	ethionamide
inhA	1674750	c.549T>G	synonymous_variant	1.0	isoniazid
inhA	1674771	c.570C>G	synonymous_variant	1.0	ethionamide
inhA	1674771	c.570C>G	synonymous_variant	1.0	isoniazid
inhA	1674780	c.579T>G	synonymous_variant	1.0	ethionamide
inhA	1674780	c.579T>G	synonymous_variant	1.0	isoniazid
inhA	1674786	c.585G>C	synonymous_variant	1.0	ethionamide
inhA	1674786	c.585G>C	synonymous_variant	1.0	isoniazid
inhA	1674801	c.600T>C	synonymous_variant	1.0	ethionamide
inhA	1674801	c.600T>C	synonymous_variant	1.0	isoniazid
inhA	1674804	c.603G>C	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
inhA	1674804	c.603G>C	synonymous_variant	1.0	isoniazid
inhA	1674810	c.609C>G	synonymous_variant	1.0	ethionamide
inhA	1674810	c.609C>G	synonymous_variant	1.0	isoniazid
inhA	1674813	c.612C>G	synonymous_variant	1.0	ethionamide
inhA	1674813	c.612C>G	synonymous_variant	1.0	isoniazid
inhA	1674816	c.615T>A	synonymous_variant	1.0	ethionamide
inhA	1674816	c.615T>A	synonymous_variant	1.0	isoniazid
inhA	1674822	c.621C>G	synonymous_variant	1.0	ethionamide
inhA	1674822	c.621C>G	synonymous_variant	1.0	isoniazid
inhA	1674825	c.624C>T	synonymous_variant	1.0	ethionamide
inhA	1674825	c.624C>T	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674828	c.627G>A	synonymous_variant	1.0	ethionamide
inhA	1674828	c.627G>A	synonymous_variant	1.0	isoniazid
inhA	1674839	p.Ala213Glu	missense_variant	1.0	ethionamide
inhA	1674839	p.Ala213Glu	missense_variant	1.0	isoniazid
inhA	1674846	p.Ile215Met	missense_variant	1.0	ethionamide
inhA	1674846	p.Ile215Met	missense_variant	1.0	isoniazid
inhA	1674848	p.Gln216Arg	missense_variant	1.0	ethionamide
inhA	1674848	p.Gln216Arg	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674870	c.669T>C	synonymous_variant	1.0	ethionamide
inhA	1674870	c.669T>C	synonymous_variant	1.0	isoniazid
inhA	1674879	c.678T>G	synonymous_variant	1.0	ethionamide
inhA	1674879	c.678T>G	synonymous_variant	1.0	isoniazid
inhA	1674882	c.681G>C	synonymous_variant	1.0	ethionamide
inhA	1674882	c.681G>C	synonymous_variant	1.0	isoniazid
inhA	1674883	p.Ile228Val	missense_variant	1.0	ethionamide	Uncertain significance
inhA	1674883	p.Ile228Val	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674892	p.Asn231Asp	missense_variant	1.0	ethionamide	Uncertain significance
inhA	1674892	p.Asn231Asp	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674904	p.Ala235Pro	missense_variant	0.96	ethionamide
inhA	1674904	p.Ala235Pro	missense_variant	0.96	isoniazid
rpsA	1833537	c.-5_-1delACAATinsCCAC	upstream_gene_variant	0.83	pyrazinamide
rpsA	1833547	c.6G>A	synonymous_variant	0.87	pyrazinamide
rpsA	1833554	p.Thr5Ser	missense_variant	0.88	pyrazinamide
rpsA	1833568	c.27G>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
rpsA	1833589	c.48A>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833595	c.54T>G	synonymous_variant	0.97	pyrazinamide
rpsA	1833616	c.75A>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833619	c.78A>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833628	c.87G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1833634	c.93G>A	synonymous_variant	0.98	pyrazinamide
rpsA	1833664	c.123C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833667	c.126C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833676	c.135A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833679	c.138G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833685	c.144G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833691	c.150G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1833694	c.153G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833697	c.156C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833709	c.168C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833733	c.192C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833734	p.Ala65Ser	missense_variant	1.0	pyrazinamide
rpsA	1833745	c.204G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833787	c.246C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833790	c.249T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833793	c.252C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833811	c.270G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833832	c.291G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833862	c.321G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833892	c.351G>A	synonymous_variant	0.97	pyrazinamide
rpsA	1833894	p.Ala118Glu	missense_variant	0.97	pyrazinamide
rpsA	1833901	c.360G>A	synonymous_variant	0.97	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	0.96	pyrazinamide
rpsA	1833949	c.408T>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833970	c.429G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	0.96	pyrazinamide
rpsA	1833991	c.450C>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834000	c.459G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834012	c.471G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1834015	c.474G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1834021	c.480C>T	synonymous_variant	0.97	pyrazinamide
rpsA	1834030	c.489C>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834093	c.552G>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834094	c.553C>T	synonymous_variant	0.94	pyrazinamide
rpsA	1834097	c.556_557delTCinsAG	synonymous_variant	0.94	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	0.94	pyrazinamide
rpsA	1834105	c.564C>T	synonymous_variant	0.95	pyrazinamide
rpsA	1834222	c.681T>C	synonymous_variant	0.85	pyrazinamide
rpsA	1834234	c.693G>T	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
rpsA	1834240	c.699T>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	0.9	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
rpsA	1834264	c.723G>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834282	c.741C>T	synonymous_variant	0.94	pyrazinamide
rpsA	1834303	c.762T>G	synonymous_variant	0.95	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
rpsA	1834366	c.825A>G	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
rpsA	1834369	c.828C>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834378	c.837T>C	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
rpsA	1834387	c.846C>T	synonymous_variant	0.99	pyrazinamide
rpsA	1834390	c.849G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834396	c.855G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834411	c.870T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834423	c.882G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834432	c.891G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834435	c.894G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834456	c.915T>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834465	c.924T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834468	c.927A>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834489	c.948T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834520	p.Ala327Ser	missense_variant	1.0	pyrazinamide
rpsA	1834528	c.987T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834543	c.1002C>G	synonymous_variant	0.97	pyrazinamide
rpsA	1834546	c.1005T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834555	c.1014T>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834556	p.Ala339Gln	missense_variant	0.98	pyrazinamide
rpsA	1834606	c.1065C>T	synonymous_variant	0.95	pyrazinamide
rpsA	1834609	c.1068T>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834619	c.1078T>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834627	c.1086C>G	synonymous_variant	0.97	pyrazinamide
rpsA	1834633	c.1092A>G	synonymous_variant	0.96	pyrazinamide
rpsA	1834639	c.1098T>C	synonymous_variant	0.96	pyrazinamide
rpsA	1834649	p.Thr370Leu	missense_variant	0.96	pyrazinamide
rpsA	1834666	c.1125G>C	synonymous_variant	0.96	pyrazinamide
rpsA	1834667	p.Ala376Ser	missense_variant	0.96	pyrazinamide
rpsA	1834690	c.1149T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834720	c.1179C>G	synonymous_variant	0.96	pyrazinamide
rpsA	1834733	p.Ala398Pro	missense_variant	0.96	pyrazinamide
rpsA	1834738	c.1197A>G	synonymous_variant	0.96	pyrazinamide
rpsA	1834753	c.1212T>C	synonymous_variant	0.93	pyrazinamide
rpsA	1834759	c.1218A>T	synonymous_variant	0.91	pyrazinamide
rpsA	1834765	c.1224A>G	synonymous_variant	0.91	pyrazinamide
rpsA	1834774	c.1233C>T	synonymous_variant	0.89	pyrazinamide
rpsA	1834776	p.Ala412Glu	missense_variant	0.89	pyrazinamide
rpsA	1834780	c.1239A>G	synonymous_variant	0.89	pyrazinamide
rpsA	1834786	c.1245A>G	synonymous_variant	0.89	pyrazinamide
rpsA	1834789	c.1248T>C	synonymous_variant	0.88	pyrazinamide
rpsA	1834792	c.1251G>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834811	c.1270C>A	synonymous_variant	0.88	pyrazinamide
tsnR	1853361	c.-245T>C	upstream_gene_variant	1.0	linezolid
tsnR	1853370	c.-236_-234delGCAinsTG	upstream_gene_variant	0.99	linezolid
tsnR	1853384	c.-222G>C	upstream_gene_variant	0.99	linezolid
tsnR	1853387	c.-219T>G	upstream_gene_variant	0.99	linezolid
tsnR	1853420	c.-186T>G	upstream_gene_variant	0.99	linezolid
tsnR	1853432	c.-174G>C	upstream_gene_variant	0.99	linezolid
tsnR	1853456	c.-150C>T	upstream_gene_variant	0.98	linezolid
tsnR	1853459	c.-147G>C	upstream_gene_variant	0.98	linezolid
tsnR	1853462	c.-144A>G	upstream_gene_variant	0.98	linezolid
tsnR	1853474	c.-132C>G	upstream_gene_variant	0.98	linezolid
tsnR	1853477	c.-129T>C	upstream_gene_variant	0.98	linezolid
tsnR	1853480	c.-126G>C	upstream_gene_variant	0.96	linezolid
tsnR	1853481	c.-125A>G	upstream_gene_variant	0.96	linezolid
tsnR	1853495	c.-111G>C	upstream_gene_variant	0.93	linezolid
tsnR	1853498	c.-108G>C	upstream_gene_variant	0.93	linezolid
tsnR	1853513	c.-93C>G	upstream_gene_variant	0.92	linezolid
tsnR	1853516	c.-90C>G	upstream_gene_variant	0.92	linezolid
tsnR	1853523	c.-83C>A	upstream_gene_variant	0.94	linezolid
tsnR	1853527	c.-79C>G	upstream_gene_variant	0.94	linezolid
tsnR	1853531	c.-75A>G	upstream_gene_variant	0.94	linezolid
tsnR	1853539	c.-67_-66delAAinsCT	upstream_gene_variant	0.92	linezolid
tsnR	1853552	c.-54C>G	upstream_gene_variant	0.9	linezolid
ndh	2102233	c.810G>A	synonymous_variant	0.7	ethionamide	Not assoc w R - Interim
					delamanid
					isoniazid	Not assoc w R - Interim
ndh	2102242	c.801G>C	synonymous_variant	0.7	ethionamide
					delamanid
					isoniazid
ndh	2102247	p.Val266Ile	missense_variant	0.7	ethionamide
					delamanid
					isoniazid
ndh	2102259	p.Ser262Ala	missense_variant	0.73	ethionamide
					delamanid
					isoniazid
ndh	2102269	c.774C>G	synonymous_variant	0.8	ethionamide
					delamanid
					isoniazid
ndh	2102275	c.768C>G	synonymous_variant	0.8	ethionamide
					delamanid
					isoniazid
ndh	2102308	c.735G>C	synonymous_variant	0.7	ethionamide
					delamanid
					isoniazid
ndh	2102317	p.Glu242Asp	missense_variant	0.7	ethionamide
					delamanid
					isoniazid
ndh	2102320	c.723G>C	synonymous_variant	0.64	ethionamide
					delamanid
					isoniazid
ndh	2102328	p.Leu239Met	missense_variant	0.64	ethionamide
					delamanid
					isoniazid
ndh	2102334	p.Gln237Glu	missense_variant	0.64	ethionamide
					delamanid
					isoniazid
kasA	2517917	c.-198G>T	upstream_gene_variant	0.98	isoniazid
kasA	2517941	c.-174C>G	upstream_gene_variant	1.0	isoniazid
kasA	2517968	c.-147T>G	upstream_gene_variant	1.0	isoniazid
kasA	2517974	c.-141T>C	upstream_gene_variant	1.0	isoniazid
kasA	2517980	c.-135C>T	upstream_gene_variant	1.0	isoniazid
kasA	2517989	c.-126T>C	upstream_gene_variant	1.0	isoniazid
kasA	2518528	c.414C>G	synonymous_variant	1.0	isoniazid
kasA	2518540	c.426T>G	synonymous_variant	1.0	isoniazid
kasA	2518555	c.441C>G	synonymous_variant	1.0	isoniazid
kasA	2518564	c.450C>G	synonymous_variant	1.0	isoniazid
kasA	2518567	c.453G>C	synonymous_variant	1.0	isoniazid
kasA	2518573	c.459G>C	synonymous_variant	1.0	isoniazid
kasA	2518574	p.Ile154Val	missense_variant	1.0	isoniazid
kasA	2518579	c.465T>G	synonymous_variant	1.0	isoniazid
kasA	2518582	c.468G>T	synonymous_variant	1.0	isoniazid
kasA	2518588	c.474T>G	synonymous_variant	1.0	isoniazid
kasA	2518591	c.477G>A	synonymous_variant	1.0	isoniazid
kasA	2518600	c.486C>A	synonymous_variant	1.0	isoniazid
kasA	2518603	c.489G>C	synonymous_variant	1.0	isoniazid
kasA	2518607	c.493_495delATGinsCC	frameshift_variant&missense_variant	1.0	isoniazid
kasA	2518627	c.513T>C	synonymous_variant	1.0	isoniazid
kasA	2518642	c.528A>G	synonymous_variant	1.0	isoniazid
kasA	2518672	c.558G>C	synonymous_variant	1.0	isoniazid
kasA	2518678	c.564C>T	synonymous_variant	1.0	isoniazid
kasA	2518688	p.Val192Ile	missense_variant	0.95	isoniazid
kasA	2518693	c.579C>G	synonymous_variant	0.94	isoniazid
kasA	2518696	c.582C>G	synonymous_variant	0.93	isoniazid
kasA	2518702	c.588C>A	synonymous_variant	0.92	isoniazid
kasA	2518705	c.591T>C	synonymous_variant	0.92	isoniazid
kasA	2518711	c.597A>G	synonymous_variant	0.92	isoniazid
kasA	2518714	c.600A>C	synonymous_variant	0.92	isoniazid
kasA	2518715	p.Pro201Gly	missense_variant	0.92	isoniazid
kasA	2518732	c.618C>G	synonymous_variant	0.92	isoniazid
kasA	2518747	c.633C>G	synonymous_variant	0.85	isoniazid
kasA	2518756	c.642G>C	synonymous_variant	0.83	isoniazid
kasA	2519224	c.1110C>G	synonymous_variant	1.0	isoniazid
kasA	2519227	c.1113G>C	synonymous_variant	1.0	isoniazid
kasA	2519233	c.1119C>T	synonymous_variant	1.0	isoniazid
kasA	2519236	c.1122G>A	synonymous_variant	1.0	isoniazid
kasA	2519239	c.1125A>C	synonymous_variant	1.0	isoniazid
kasA	2519242	c.1128C>G	synonymous_variant	1.0	isoniazid
kasA	2519245	c.1131T>C	synonymous_variant	1.0	isoniazid
kasA	2519257	c.1143C>T	synonymous_variant	1.0	isoniazid
kasA	2519260	c.1146T>C	synonymous_variant	1.0	isoniazid
kasA	2519263	c.1149C>T	synonymous_variant	1.0	isoniazid
kasA	2519269	c.1155C>T	synonymous_variant	1.0	isoniazid
kasA	2519272	c.1158C>G	synonymous_variant	1.0	isoniazid
kasA	2519278	c.1164A>G	synonymous_variant	1.0	isoniazid
kasA	2519281	c.1167G>T	synonymous_variant	1.0	isoniazid
kasA	2519284	c.1170C>A	synonymous_variant	1.0	isoniazid
kasA	2519293	c.1179T>C	synonymous_variant	1.0	isoniazid
kasA	2519298	p.Arg395Gln	missense_variant	1.0	isoniazid
kasA	2519305	c.1191A>C	synonymous_variant	1.0	isoniazid
kasA	2519306	p.Val398Ile	missense_variant	1.0	isoniazid
kasA	2519329	c.1215C>T	synonymous_variant	1.0	isoniazid
kasA	2519332	c.1218C>A	synonymous_variant	1.0	isoniazid
folC	2746702	c.897G>C	synonymous_variant	0.82	para-aminosalicylic_acid
folC	2746705	c.894G>A	synonymous_variant	0.82	para-aminosalicylic_acid
folC	2746708	c.891C>T	synonymous_variant	0.82	para-aminosalicylic_acid
folC	2746728	c.871T>C	synonymous_variant	0.82	para-aminosalicylic_acid
folC	2746738	c.861C>G	synonymous_variant	0.9	para-aminosalicylic_acid
folC	2746744	c.855T>G	synonymous_variant	0.9	para-aminosalicylic_acid
Rv2477c	2782549	c.1494T>C	synonymous_variant	0.85	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2782555	c.1488G>C	synonymous_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2782567	c.1476C>G	synonymous_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783025	c.1018C>T	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783038	c.1003_1005delGCCinsCG	frameshift_variant&synonymous_variant	0.91	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2783044	c.999G>C	synonymous_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783051	p.Tyr331Phe	missense_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783059	c.984T>C	synonymous_variant	0.95	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783065	c.978C>T	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2783068	p.Asp325Glu	missense_variant	0.95	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783077	c.966T>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783092	c.951A>C	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783095	c.948C>G	synonymous_variant	0.96	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R
					amikacin	Not assoc w R - Interim
Rv2477c	2783098	c.945C>G	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783101	c.942G>T	synonymous_variant	0.96	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783116	c.927T>C	synonymous_variant	0.98	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783140	c.901_903delACCinsTA	frameshift_variant&missense_variant	1.0	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2783149	c.894G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783155	c.888C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783158	c.885A>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783182	c.861C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783185	c.858G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783193	p.Ser284Gly	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783194	c.849A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783203	c.840C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783215	c.828G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783218	c.825C>G	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783224	c.819C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783230	c.813T>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2783239	c.804G>A	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783242	p.Thr267Lys	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783245	c.796_798delTTGinsCC	frameshift_variant&missense_variant	1.0	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2783254	c.789A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783263	c.780G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783275	c.768C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783278	c.765A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783289	p.Leu252Ile	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783290	c.753G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783299	c.744A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783302	c.741A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783311	c.732T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783314	c.729C>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2783332	c.711T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783335	c.708C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783350	c.693T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783353	c.690T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783359	c.684G>A	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783362	c.681G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783371	c.672A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783374	c.669G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783395	c.648T>G	synonymous_variant	0.95	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783485	c.558G>C	synonymous_variant	0.85	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783488	c.555G>A	synonymous_variant	0.79	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783497	c.544_546delTTGinsCC	frameshift_variant&missense_variant	0.79	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2783502	c.541T>C	synonymous_variant	0.79	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2783512	c.531A>G	synonymous_variant	0.79	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783520	c.523T>C	synonymous_variant	0.75	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2783527	c.516A>G	synonymous_variant	0.7	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783535	c.508C>T	synonymous_variant	0.64	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783548	c.495T>G	synonymous_variant	0.77	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783563	c.480A>C	synonymous_variant	0.76	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783566	c.475_477delAACinsCT	frameshift_variant&missense_variant	0.76	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2783572	c.471A>C	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783575	c.468G>C	synonymous_variant	0.81	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783586	p.Ala153Pro	missense_variant	0.82	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783593	c.450T>C	synonymous_variant	0.82	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783599	c.444G>T	synonymous_variant	0.87	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783605	c.438T>C	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783611	c.432C>G	synonymous_variant	0.88	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783626	c.415_417delGCGinsTC	frameshift_variant&missense_variant	0.86	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					kanamycin	Uncertain significance
					rifampicin	Uncertain significance
					amikacin	Uncertain significance
Rv2477c	2783629	c.414C>T	synonymous_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783634	p.Leu137Ile	missense_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783641	c.402G>A	synonymous_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783650	p.His131Ala	missense_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783656	c.387G>C	synonymous_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783665	c.378A>G	synonymous_variant	0.86	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783674	c.369T>C	synonymous_variant	0.87	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783683	c.360A>G	synonymous_variant	0.91	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783689	c.354G>C	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783821	c.222A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783833	c.210G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783836	c.207C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783872	c.171G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783875	p.Lys56Thr	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783883	c.160T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783884	c.159T>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783914	c.129T>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783926	c.117C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783938	c.105T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783947	c.96C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783953	c.90G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783957	p.Tyr29Leu	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783962	p.Ser27Asn	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783967	c.76T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783968	p.Thr25Ser	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783971	c.72G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783980	c.63C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783986	c.57G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2783992	c.51T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin
Rv2477c	2784017	p.Lys9Arg	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784024	p.Thr7Ser	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784025	c.18C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784034	c.9G>A	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
Rv2477c	2784037	c.6T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784047	c.-5G>A	upstream_gene_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2477c	2784051	c.-9C>G	upstream_gene_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					kanamycin
					rifampicin
					amikacin
Rv2681	2996350	c.-389C>A	upstream_gene_variant	1.0	capreomycin
Rv2680	2996360	p.Met86Leu	missense_variant	1.0	capreomycin
Rv2680	2996366	c.262_264delTATinsCC	frameshift_variant&missense_variant	1.0	capreomycin	Uncertain significance
Rv2681	2996374	c.-365G>C	upstream_gene_variant	1.0	capreomycin
Rv2680	2996377	p.Asp91Glu	missense_variant	1.0	capreomycin
Rv2680	2996381	p.Ser93Ala	missense_variant	1.0	capreomycin
Rv2680	2996386	c.282T>C	synonymous_variant	1.0	capreomycin	Not assoc w R - Interim
Rv2681	2996389	c.-350A>G	upstream_gene_variant	1.0	capreomycin
Rv2681	2996401	c.-338T>G	upstream_gene_variant	1.0	capreomycin
Rv2680	2996404	p.Ile100Met	missense_variant	1.0	capreomycin
Rv2681	2996407	c.-332C>G	upstream_gene_variant	1.0	capreomycin
Rv2681	2996419	c.-320T>C	upstream_gene_variant	1.0	capreomycin
Rv2680	2996420	p.Val106Ile	missense_variant	1.0	capreomycin
Rv2681	2996440	c.-299G>C	upstream_gene_variant	1.0	capreomycin
Rv2681	2996443	c.-296T>C	upstream_gene_variant	0.93	capreomycin
Rv2680	2996446	c.342A>G	synonymous_variant	0.93	capreomycin	Not assoc w R - Interim
Rv2681	2996449	c.-290C>G	upstream_gene_variant	0.93	capreomycin
Rv2681	2996452	c.-287C>G	upstream_gene_variant	0.93	capreomycin
Rv2681	2996458	c.-281C>G	upstream_gene_variant	0.93	capreomycin
Rv2681	2996476	c.-263A>G	upstream_gene_variant	0.93	capreomycin
Rv2681	2996491	c.-248G>C	upstream_gene_variant	0.92	capreomycin
Rv2752c	3065547	c.645A>G	synonymous_variant	0.9	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065553	c.639A>G	synonymous_variant	0.92	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065559	c.633C>G	synonymous_variant	0.92	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065562	c.630T>G	synonymous_variant	0.93	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065576	p.Ala206Ser	missense_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065592	c.600G>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065595	p.Leu199Phe	missense_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065607	c.585C>G	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065612	p.Thr194Ala	missense_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065613	c.579C>T	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065639	c.553C>T	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
					moxifloxacin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
Rv2752c	3065640	c.552T>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065643	c.549C>G	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065646	c.546C>G	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065649	p.Arg181Gln	missense_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065653	p.Gly180Asp	missense_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065659	p.Pro178Leu	missense_variant	0.94	ethambutol	Uncertain significance
					moxifloxacin
					levofloxacin
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
Rv2752c	3065661	c.531A>G	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065666	c.526T>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
Rv2752c	3065675	p.Phe173Leu	missense_variant	0.94	ethambutol
					moxifloxacin
					levofloxacin
					rifampicin
					isoniazid
thyX	3067309	p.Ile213Val	missense_variant	0.8	para-aminosalicylic_acid
thyX	3067313	c.633G>C	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067316	c.630A>G	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067319	c.627G>C	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067322	c.624C>T	synonymous_variant	0.8	para-aminosalicylic_acid
thyX	3067325	c.621A>G	synonymous_variant	0.83	para-aminosalicylic_acid
thyX	3067349	c.597G>C	synonymous_variant	0.83	para-aminosalicylic_acid
thyX	3067354	p.Met198Val	missense_variant	0.75	para-aminosalicylic_acid
thyX	3067355	c.591A>G	synonymous_variant	0.75	para-aminosalicylic_acid
thyX	3067364	c.582C>T	synonymous_variant	0.75	para-aminosalicylic_acid
thyX	3067376	c.570G>C	synonymous_variant	0.77	para-aminosalicylic_acid
thyX	3067382	c.564C>T	synonymous_variant	0.77	para-aminosalicylic_acid
thyX	3067385	c.561C>G	synonymous_variant	0.77	para-aminosalicylic_acid
thyX	3067391	c.555G>C	synonymous_variant	0.83	para-aminosalicylic_acid
thyX	3067403	c.543C>A	synonymous_variant	0.85	para-aminosalicylic_acid
thyX	3067406	c.540A>G	synonymous_variant	0.85	para-aminosalicylic_acid
thyX	3067412	c.534C>G	synonymous_variant	0.85	para-aminosalicylic_acid
thyX	3067418	c.528C>G	synonymous_variant	0.85	para-aminosalicylic_acid
thyX	3067619	c.327A>C	synonymous_variant	0.81	para-aminosalicylic_acid
thyX	3067634	c.312C>G	synonymous_variant	0.84	para-aminosalicylic_acid
thyX	3067640	c.306G>A	synonymous_variant	0.85	para-aminosalicylic_acid
thyX	3067652	c.294T>C	synonymous_variant	0.86	para-aminosalicylic_acid
thyX	3067655	c.291G>C	synonymous_variant	0.86	para-aminosalicylic_acid
thyX	3067661	c.285C>G	synonymous_variant	0.83	para-aminosalicylic_acid
thyX	3067665	p.Ile94Thr	missense_variant	0.83	para-aminosalicylic_acid
thyX	3067685	c.261A>G	synonymous_variant	0.88	para-aminosalicylic_acid
thyX	3067688	c.258G>C	synonymous_variant	0.89	para-aminosalicylic_acid
thyX	3067694	c.252G>C	synonymous_variant	0.93	para-aminosalicylic_acid
thyX	3067715	c.229_231delAGCinsTCG	synonymous_variant	0.91	para-aminosalicylic_acid
thyX	3067718	c.228C>G	synonymous_variant	0.91	para-aminosalicylic_acid
thyX	3067721	c.225T>C	synonymous_variant	0.92	para-aminosalicylic_acid
thyX	3067727	c.219A>C	synonymous_variant	0.95	para-aminosalicylic_acid
thyX	3067739	c.207T>C	synonymous_variant	0.93	para-aminosalicylic_acid
thyX	3067742	c.204A>G	synonymous_variant	0.93	para-aminosalicylic_acid
thyX	3067763	c.181_183delCTCinsGG	frameshift_variant&missense_variant	0.93	para-aminosalicylic_acid
thyX	3067770	p.Gly59Ala	missense_variant	0.93	para-aminosalicylic_acid
thyX	3067787	p.Lys53Arg	missense_variant	0.93	para-aminosalicylic_acid
thyX	3067790	c.156C>G	synonymous_variant	0.93	para-aminosalicylic_acid
thyX	3067814	c.132T>C	synonymous_variant	0.96	para-aminosalicylic_acid
thyX	3067838	c.108C>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyX	3067847	c.99C>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyX	3067850	c.96A>G	synonymous_variant	0.9	para-aminosalicylic_acid
thyX	3067856	p.Asp30Glu	missense_variant	0.9	para-aminosalicylic_acid
thyX	3067869	p.Thr26Ser	missense_variant	0.9	para-aminosalicylic_acid
thyX	3067886	c.60A>C	synonymous_variant	0.91	para-aminosalicylic_acid
thyX	3067889	c.57C>G	synonymous_variant	0.83	para-aminosalicylic_acid
thyX	3067894	c.52T>C	synonymous_variant	0.89	para-aminosalicylic_acid
thyX	3067898	p.Asp16Glu	missense_variant	0.94	para-aminosalicylic_acid
thyX	3067901	c.45C>G	synonymous_variant	0.94	para-aminosalicylic_acid
thyA	3073818	c.654G>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073821	c.651G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073824	c.648A>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073827	c.645A>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073839	c.633T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073863	c.609T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073884	c.588C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073888	p.Ser195Glu	missense_variant	1.0	para-aminosalicylic_acid
thyA	3073892	c.580T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073893	c.579C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073902	c.570C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073905	c.567C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073920	c.552C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073925	c.547T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073929	c.543T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073953	c.519T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073956	c.516G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073959	c.513T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073977	c.495A>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073983	c.489C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3073989	c.483T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074000	c.472C>A	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074004	c.468T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074025	p.Phe149Leu	missense_variant	1.0	para-aminosalicylic_acid
thyA	3074031	c.441T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074034	c.438T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074053	p.Arg140Gln	missense_variant	1.0	para-aminosalicylic_acid
thyA	3074055	p.Glu139Ala	missense_variant	1.0	para-aminosalicylic_acid
thyA	3074061	c.409_411delGAAinsCG	frameshift_variant&missense_variant	1.0	para-aminosalicylic_acid
thyA	3074070	c.402C>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074076	c.396C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074082	c.390G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074094	c.378G>T	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074097	c.375C>G	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074106	c.366T>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074112	p.Arg120Gln	missense_variant	1.0	para-aminosalicylic_acid
thyA	3074115	c.357G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074130	c.342G>C	synonymous_variant	1.0	para-aminosalicylic_acid
thyA	3074154	c.318T>C	synonymous_variant	0.96	para-aminosalicylic_acid
thyA	3074157	c.315C>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074160	c.312A>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074163	c.307_309delGCTinsAC	frameshift_variant&missense_variant	0.95	para-aminosalicylic_acid
thyA	3074175	c.297A>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074181	c.291A>G	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074184	c.288A>C	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074187	c.285T>C	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074193	c.277_279delATCinsGG	frameshift_variant&missense_variant	0.95	para-aminosalicylic_acid
thyA	3074199	c.273G>A	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074205	p.Glu89Asp	missense_variant	0.95	para-aminosalicylic_acid
thyA	3074208	c.264C>T	synonymous_variant	0.95	para-aminosalicylic_acid
thyA	3074214	p.Asp86Glu	missense_variant	0.95	para-aminosalicylic_acid
lpqB	3624665	c.246C>T	synonymous_variant	0.91	bedaquiline
lpqB	3624665	c.246C>T	synonymous_variant	0.91	rifampicin
lpqB	3624671	p.Ala80Gly	missense_variant	0.82	bedaquiline
lpqB	3624671	p.Ala80Gly	missense_variant	0.82	rifampicin
lpqB	3624675	p.Asn79Arg	missense_variant	0.91	bedaquiline
lpqB	3624675	p.Asn79Arg	missense_variant	0.91	rifampicin
lpqB	3624677	c.234C>G	synonymous_variant	0.91	bedaquiline
lpqB	3624677	c.234C>G	synonymous_variant	0.91	rifampicin
lpqB	3624683	c.228G>C	synonymous_variant	0.91	bedaquiline
lpqB	3624683	c.228G>C	synonymous_variant	0.91	rifampicin
lpqB	3624701	c.210T>C	synonymous_variant	1.0	bedaquiline
lpqB	3624701	c.210T>C	synonymous_variant	1.0	rifampicin
lpqB	3624704	c.207G>T	synonymous_variant	1.0	bedaquiline
lpqB	3624704	c.207G>T	synonymous_variant	1.0	rifampicin
lpqB	3624707	c.204G>C	synonymous_variant	1.0	bedaquiline
lpqB	3624707	c.204G>C	synonymous_variant	1.0	rifampicin
lpqB	3624713	c.198C>T	synonymous_variant	1.0	bedaquiline
lpqB	3624713	c.198C>T	synonymous_variant	1.0	rifampicin
lpqB	3624725	c.186G>C	synonymous_variant	1.0	bedaquiline
lpqB	3624725	c.186G>C	synonymous_variant	1.0	rifampicin
lpqB	3624728	c.183C>T	synonymous_variant	1.0	bedaquiline
lpqB	3624728	c.183C>T	synonymous_variant	1.0	rifampicin
lpqB	3624734	c.177A>C	synonymous_variant	1.0	bedaquiline
lpqB	3624734	c.177A>C	synonymous_variant	1.0	rifampicin
lpqB	3624755	c.156A>G	synonymous_variant	1.0	bedaquiline
lpqB	3624755	c.156A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
lpqB	3624761	c.150G>C	synonymous_variant	1.0	bedaquiline
lpqB	3624761	c.150G>C	synonymous_variant	1.0	rifampicin
lpqB	3624776	c.133_135delGGTinsAC	frameshift_variant&missense_variant	0.92	bedaquiline
lpqB	3624776	c.133_135delGGTinsAC	frameshift_variant&missense_variant	0.92	rifampicin	Uncertain significance
lpqB	3624783	p.Ser43Thr	missense_variant	0.91	bedaquiline
lpqB	3624783	p.Ser43Thr	missense_variant	0.91	rifampicin
lpqB	3624785	c.126G>C	synonymous_variant	0.91	bedaquiline
lpqB	3624785	c.126G>C	synonymous_variant	0.91	rifampicin
lpqB	3625165	c.-255G>C	upstream_gene_variant	0.85	bedaquiline
lpqB	3625165	c.-255G>C	upstream_gene_variant	0.85	rifampicin
lpqB	3625168	c.-258G>T	upstream_gene_variant	0.85	bedaquiline
lpqB	3625168	c.-258G>T	upstream_gene_variant	0.85	rifampicin
lpqB	3625183	c.-273G>C	upstream_gene_variant	0.79	bedaquiline
lpqB	3625183	c.-273G>C	upstream_gene_variant	0.79	rifampicin
lpqB	3625186	c.-276T>A	upstream_gene_variant	0.79	bedaquiline
lpqB	3625186	c.-276T>A	upstream_gene_variant	0.79	rifampicin
mtrB	3625189	c.1425A>G	synonymous_variant	0.79	bedaquiline
mtrB	3625189	c.1425A>G	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
lpqB	3625195	c.-285A>G	upstream_gene_variant	0.79	bedaquiline
lpqB	3625195	c.-285A>G	upstream_gene_variant	0.79	rifampicin
lpqB	3625198	c.-288C>G	upstream_gene_variant	0.79	bedaquiline
lpqB	3625198	c.-288C>G	upstream_gene_variant	0.79	rifampicin
lpqB	3625204	c.-294G>C	upstream_gene_variant	0.75	bedaquiline
lpqB	3625204	c.-294G>C	upstream_gene_variant	0.75	rifampicin
lpqB	3625207	c.-297C>G	upstream_gene_variant	0.69	bedaquiline
lpqB	3625207	c.-297C>G	upstream_gene_variant	0.69	rifampicin
mtrB	3625222	c.1392T>C	synonymous_variant	0.87	bedaquiline
mtrB	3625222	c.1392T>C	synonymous_variant	0.87	rifampicin	Not assoc w R - Interim
lpqB	3625243	c.-333T>G	upstream_gene_variant	0.9	bedaquiline
lpqB	3625243	c.-333T>G	upstream_gene_variant	0.9	rifampicin
lpqB	3625246	c.-336G>C	upstream_gene_variant	0.9	bedaquiline
lpqB	3625246	c.-336G>C	upstream_gene_variant	0.9	rifampicin
lpqB	3625255	c.-345T>C	upstream_gene_variant	0.9	bedaquiline
lpqB	3625255	c.-345T>C	upstream_gene_variant	0.9	rifampicin
lpqB	3625258	c.-348G>C	upstream_gene_variant	0.89	bedaquiline
lpqB	3625258	c.-348G>C	upstream_gene_variant	0.89	rifampicin
mtrB	3625262	p.Tyr451Phe	missense_variant	0.89	bedaquiline
mtrB	3625262	p.Tyr451Phe	missense_variant	0.89	rifampicin
mtrB	3625264	c.1350C>T	synonymous_variant	0.89	bedaquiline	Not assoc w R - Interim
mtrB	3625264	c.1350C>T	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
mtrB	3625267	c.1347T>C	synonymous_variant	0.89	bedaquiline
mtrB	3625267	c.1347T>C	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
lpqB	3625270	c.-360G>C	upstream_gene_variant	0.89	bedaquiline
lpqB	3625270	c.-360G>C	upstream_gene_variant	0.89	rifampicin
lpqB	3625273	c.-363C>G	upstream_gene_variant	0.85	bedaquiline
lpqB	3625273	c.-363C>G	upstream_gene_variant	0.85	rifampicin
lpqB	3625279	c.-369C>G	upstream_gene_variant	0.85	bedaquiline
lpqB	3625279	c.-369C>G	upstream_gene_variant	0.85	rifampicin
lpqB	3625282	c.-372C>G	upstream_gene_variant	0.85	bedaquiline
lpqB	3625282	c.-372C>G	upstream_gene_variant	0.85	rifampicin
lpqB	3625285	c.-375G>C	upstream_gene_variant	0.86	bedaquiline
lpqB	3625285	c.-375G>C	upstream_gene_variant	0.86	rifampicin
lpqB	3625291	c.-381A>G	upstream_gene_variant	0.86	bedaquiline
lpqB	3625291	c.-381A>G	upstream_gene_variant	0.86	rifampicin
mtrB	3625313	p.Arg434Lys	missense_variant	0.84	bedaquiline
mtrB	3625313	p.Arg434Lys	missense_variant	0.84	rifampicin
lpqB	3625315	c.-405G>C	upstream_gene_variant	0.83	bedaquiline
lpqB	3625315	c.-405G>C	upstream_gene_variant	0.83	rifampicin
lpqB	3625318	c.-408G>C	upstream_gene_variant	0.83	bedaquiline
lpqB	3625318	c.-408G>C	upstream_gene_variant	0.83	rifampicin
mtrB	3625321	c.1293A>G	synonymous_variant	0.83	bedaquiline	Not assoc w R - Interim
mtrB	3625321	c.1293A>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
lpqB	3625327	c.-417A>G	upstream_gene_variant	0.79	bedaquiline
lpqB	3625327	c.-417A>G	upstream_gene_variant	0.79	rifampicin
mtrB	3625342	c.1272C>G	synonymous_variant	0.83	bedaquiline	Not assoc w R - Interim
mtrB	3625342	c.1272C>G	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
lpqB	3625345	c.-435T>C	upstream_gene_variant	0.81	bedaquiline
lpqB	3625345	c.-435T>C	upstream_gene_variant	0.81	rifampicin
lpqB	3625528	c.-618G>T	upstream_gene_variant	0.86	bedaquiline
lpqB	3625528	c.-618G>T	upstream_gene_variant	0.86	rifampicin
lpqB	3625531	c.-621C>G	upstream_gene_variant	0.92	bedaquiline
lpqB	3625531	c.-621C>G	upstream_gene_variant	0.92	rifampicin
lpqB	3625537	c.-627T>C	upstream_gene_variant	0.93	bedaquiline
lpqB	3625537	c.-627T>C	upstream_gene_variant	0.93	rifampicin
lpqB	3625540	c.-630G>C	upstream_gene_variant	0.95	bedaquiline
lpqB	3625540	c.-630G>C	upstream_gene_variant	0.95	rifampicin
lpqB	3625546	c.-636C>T	upstream_gene_variant	0.95	bedaquiline
lpqB	3625546	c.-636C>T	upstream_gene_variant	0.95	rifampicin
mtrB	3625569	c.1045T>C	synonymous_variant	0.94	bedaquiline
mtrB	3625569	c.1045T>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
lpqB	3625570	c.-660G>C	upstream_gene_variant	0.94	bedaquiline
lpqB	3625570	c.-660G>C	upstream_gene_variant	0.94	rifampicin
lpqB	3625579	c.-669A>C	upstream_gene_variant	0.95	bedaquiline
lpqB	3625579	c.-669A>C	upstream_gene_variant	0.95	rifampicin
lpqB	3625594	c.-684T>C	upstream_gene_variant	0.96	bedaquiline
lpqB	3625594	c.-684T>C	upstream_gene_variant	0.96	rifampicin
mtrB	3625607	p.Thr336Ile	missense_variant	0.98	bedaquiline
mtrB	3625607	p.Thr336Ile	missense_variant	0.98	rifampicin	Uncertain significance
lpqB	3625609	c.-699C>G	upstream_gene_variant	0.98	bedaquiline
lpqB	3625609	c.-699C>G	upstream_gene_variant	0.98	rifampicin
lpqB	3625612	c.-702G>C	upstream_gene_variant	0.98	bedaquiline
lpqB	3625612	c.-702G>C	upstream_gene_variant	0.98	rifampicin
mtrB	3625620	c.994C>T	synonymous_variant	0.98	bedaquiline
mtrB	3625620	c.994C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
mtrB	3625623	p.Thr331Ser	missense_variant	0.98	bedaquiline
mtrB	3625623	p.Thr331Ser	missense_variant	0.98	rifampicin
lpqB	3625624	c.-714C>G	upstream_gene_variant	0.98	bedaquiline
lpqB	3625624	c.-714C>G	upstream_gene_variant	0.98	rifampicin
mtrB	3625637	p.Ala326Asp	missense_variant	0.98	bedaquiline
mtrB	3625637	p.Ala326Asp	missense_variant	0.98	rifampicin
mtrB	3625650	p.Tyr322His	missense_variant	0.98	bedaquiline
mtrB	3625650	p.Tyr322His	missense_variant	0.98	rifampicin
mtrB	3625656	c.958T>C	synonymous_variant	0.98	bedaquiline	Not assoc w R - Interim
mtrB	3625656	c.958T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.98	bedaquiline
lpqB	3625663	c.-753G>C	upstream_gene_variant	0.98	rifampicin
lpqB	3625678	c.-768C>G	upstream_gene_variant	0.98	bedaquiline
lpqB	3625678	c.-768C>G	upstream_gene_variant	0.98	rifampicin
lpqB	3625687	c.-777G>C	upstream_gene_variant	0.98	bedaquiline
lpqB	3625687	c.-777G>C	upstream_gene_variant	0.98	rifampicin
lpqB	3625690	c.-780T>C	upstream_gene_variant	0.98	bedaquiline
lpqB	3625690	c.-780T>C	upstream_gene_variant	0.98	rifampicin
lpqB	3625696	c.-786A>G	upstream_gene_variant	0.98	bedaquiline
lpqB	3625696	c.-786A>G	upstream_gene_variant	0.98	rifampicin
mtrB	3625705	c.909C>G	synonymous_variant	0.98	bedaquiline
mtrB	3625705	c.909C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
mtrB	3625729	c.885A>G	synonymous_variant	0.97	bedaquiline
mtrB	3625729	c.885A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
mtrB	3625755	p.Ala287Thr	missense_variant	0.97	bedaquiline
mtrB	3625755	p.Ala287Thr	missense_variant	0.97	rifampicin	Uncertain significance
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.97	bedaquiline
lpqB	3625762	c.-852A>C	upstream_gene_variant	0.97	rifampicin
mtrB	3625765	c.849C>G	synonymous_variant	0.97	bedaquiline
mtrB	3625765	c.849C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
mtrB	3625774	c.840G>A	synonymous_variant	0.97	bedaquiline
mtrB	3625774	c.840G>A	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
lpqB	3625798	c.-888G>C	upstream_gene_variant	0.95	bedaquiline
lpqB	3625798	c.-888G>C	upstream_gene_variant	0.95	rifampicin
mtrB	3625806	c.808A>C	synonymous_variant	0.95	bedaquiline
mtrB	3625806	c.808A>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
mtrB	3625837	c.777C>G	synonymous_variant	0.93	bedaquiline
mtrB	3625837	c.777C>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
lpqB	3625840	c.-930A>G	upstream_gene_variant	0.93	bedaquiline
lpqB	3625840	c.-930A>G	upstream_gene_variant	0.93	rifampicin
mtrB	3625845	p.Ser257Thr	missense_variant	0.93	bedaquiline
mtrB	3625845	p.Ser257Thr	missense_variant	0.93	rifampicin
lpqB	3625864	c.-954T>G	upstream_gene_variant	0.9	bedaquiline
lpqB	3625864	c.-954T>G	upstream_gene_variant	0.9	rifampicin
mtrB	3626062	c.552T>C	synonymous_variant	0.73	bedaquiline
mtrB	3626062	c.552T>C	synonymous_variant	0.73	rifampicin
mtrB	3626065	c.549G>C	synonymous_variant	0.73	bedaquiline
mtrB	3626065	c.549G>C	synonymous_variant	0.73	rifampicin
mtrB	3626077	c.537C>G	synonymous_variant	0.73	bedaquiline
mtrB	3626077	c.537C>G	synonymous_variant	0.73	rifampicin
mtrB	3626080	c.534G>C	synonymous_variant	0.73	bedaquiline
mtrB	3626080	c.534G>C	synonymous_variant	0.73	rifampicin
mtrB	3626092	p.Gly174Ala	missense_variant	0.73	bedaquiline	Uncertain significance
mtrB	3626092	p.Gly174Ala	missense_variant	0.73	rifampicin	Uncertain significance
mtrB	3626095	p.Glu173Asp	missense_variant	0.73	bedaquiline
mtrB	3626095	p.Glu173Asp	missense_variant	0.73	rifampicin
mtrB	3626101	c.511_513delCAGinsGC	frameshift_variant&missense_variant	0.73	bedaquiline	Uncertain significance
mtrB	3626101	c.511_513delCAGinsGC	frameshift_variant&missense_variant	0.73	rifampicin	Uncertain significance
mtrB	3626123	p.Ala164Ser	missense_variant	0.8	bedaquiline
mtrB	3626123	p.Ala164Ser	missense_variant	0.8	rifampicin
mtrB	3626126	p.Ala163Val	missense_variant	0.8	bedaquiline
mtrB	3626126	p.Ala163Val	missense_variant	0.8	rifampicin
mtrB	3626131	c.483G>T	synonymous_variant	0.8	bedaquiline
mtrB	3626131	c.483G>T	synonymous_variant	0.8	rifampicin
mtrB	3626704	c.-91C>T	upstream_gene_variant	0.85	bedaquiline
mtrB	3626704	c.-91C>T	upstream_gene_variant	0.85	rifampicin
mtrA	3626711	p.Thr213Gln	missense_variant	0.89	bedaquiline
mtrA	3626711	p.Thr213Gln	missense_variant	0.89	rifampicin
mtrB	3626723	c.-110C>G	upstream_gene_variant	0.91	bedaquiline
mtrB	3626723	c.-110C>G	upstream_gene_variant	0.91	rifampicin
mtrB	3626726	c.-113T>C	upstream_gene_variant	0.91	bedaquiline
mtrB	3626726	c.-113T>C	upstream_gene_variant	0.91	rifampicin
mtrB	3626729	c.-116G>A	upstream_gene_variant	0.91	bedaquiline
mtrB	3626729	c.-116G>A	upstream_gene_variant	0.91	rifampicin
mtrB	3626732	c.-119A>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3626732	c.-119A>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626744	c.-131G>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3626744	c.-131G>C	upstream_gene_variant	0.96	rifampicin
mtrA	3626749	c.601C>T	synonymous_variant	0.93	bedaquiline	Not assoc w R - Interim
mtrA	3626749	c.601C>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrB	3626750	c.-137T>G	upstream_gene_variant	0.93	bedaquiline
mtrB	3626750	c.-137T>G	upstream_gene_variant	0.93	rifampicin
mtrB	3626756	c.-143C>T	upstream_gene_variant	0.93	bedaquiline
mtrB	3626756	c.-143C>T	upstream_gene_variant	0.93	rifampicin
mtrB	3626776	c.-163A>C	upstream_gene_variant	0.94	bedaquiline
mtrB	3626776	c.-163A>C	upstream_gene_variant	0.94	rifampicin
mtrB	3626780	c.-167T>C	upstream_gene_variant	0.94	bedaquiline
mtrB	3626780	c.-167T>C	upstream_gene_variant	0.94	rifampicin
mtrB	3626786	c.-173A>C	upstream_gene_variant	0.94	bedaquiline
mtrB	3626786	c.-173A>C	upstream_gene_variant	0.94	rifampicin
mtrB	3626798	c.-185T>C	upstream_gene_variant	0.93	bedaquiline
mtrB	3626798	c.-185T>C	upstream_gene_variant	0.93	rifampicin
mtrA	3626804	c.546A>G	synonymous_variant	0.93	bedaquiline
mtrA	3626804	c.546A>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrB	3626822	c.-209T>C	upstream_gene_variant	0.87	bedaquiline
mtrB	3626822	c.-209T>C	upstream_gene_variant	0.87	rifampicin
mtrA	3626825	c.525T>A	synonymous_variant	0.86	bedaquiline
mtrA	3626825	c.525T>A	synonymous_variant	0.86	rifampicin	Not assoc w R - Interim
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.88	bedaquiline
mtrB	3626840	c.-227C>G	upstream_gene_variant	0.88	rifampicin
mtrA	3626846	c.504G>A	synonymous_variant	0.89	bedaquiline
mtrA	3626846	c.504G>A	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
mtrB	3626858	c.-245A>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3626858	c.-245A>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626861	c.-248C>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3626861	c.-248C>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626876	c.-263A>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3626876	c.-263A>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626885	c.-272A>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3626885	c.-272A>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626890	c.-277T>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3626890	c.-277T>C	upstream_gene_variant	0.95	rifampicin
mtrB	3626891	c.-278G>C	upstream_gene_variant	0.94	bedaquiline
mtrB	3626891	c.-278G>C	upstream_gene_variant	0.94	rifampicin
mtrB	3626903	c.-290T>C	upstream_gene_variant	0.93	bedaquiline
mtrB	3626903	c.-290T>C	upstream_gene_variant	0.93	rifampicin
mtrA	3626906	c.442_444delAACinsCG	frameshift_variant&missense_variant	0.93	bedaquiline
mtrA	3626906	c.442_444delAACinsCG	frameshift_variant&missense_variant	0.93	rifampicin
mtrA	3626909	c.441C>G	synonymous_variant	0.93	bedaquiline
mtrA	3626909	c.441C>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
mtrA	3626912	c.438T>C	synonymous_variant	1.0	bedaquiline
mtrA	3626912	c.438T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3626924	c.-311G>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3626924	c.-311G>C	upstream_gene_variant	0.95	rifampicin
mtrB	3626927	c.-314G>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3626927	c.-314G>C	upstream_gene_variant	0.95	rifampicin
mtrB	3626930	c.-317A>G	upstream_gene_variant	0.95	bedaquiline
mtrB	3626930	c.-317A>G	upstream_gene_variant	0.95	rifampicin
mtrB	3626933	c.-320C>T	upstream_gene_variant	0.95	bedaquiline
mtrB	3626933	c.-320C>T	upstream_gene_variant	0.95	rifampicin
mtrA	3626939	p.Glu137Asp	missense_variant	0.96	bedaquiline
mtrA	3626939	p.Glu137Asp	missense_variant	0.96	rifampicin
mtrB	3626942	c.-329A>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3626942	c.-329A>C	upstream_gene_variant	0.96	rifampicin
mtrA	3626949	p.Ala134Gly	missense_variant	0.96	bedaquiline
mtrA	3626949	p.Ala134Gly	missense_variant	0.96	rifampicin
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.96	bedaquiline
mtrB	3626954	c.-341C>G	upstream_gene_variant	0.96	rifampicin
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.96	bedaquiline
mtrB	3626957	c.-344G>C	upstream_gene_variant	0.96	rifampicin
mtrB	3626969	c.-356C>G	upstream_gene_variant	0.97	bedaquiline
mtrB	3626969	c.-356C>G	upstream_gene_variant	0.97	rifampicin
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.97	bedaquiline
mtrB	3626972	c.-359A>G	upstream_gene_variant	0.97	rifampicin
mtrA	3626978	p.Asp124Glu	missense_variant	0.98	bedaquiline
mtrA	3626978	p.Asp124Glu	missense_variant	0.98	rifampicin	Uncertain significance
mtrB	3626999	c.-386G>C	upstream_gene_variant	0.98	bedaquiline
mtrB	3626999	c.-386G>C	upstream_gene_variant	0.98	rifampicin
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3627008	c.-395G>C	upstream_gene_variant	0.95	rifampicin
mtrB	3627011	c.-398T>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3627011	c.-398T>C	upstream_gene_variant	0.95	rifampicin
mtrB	3627014	c.-401G>C	upstream_gene_variant	0.95	bedaquiline
mtrB	3627014	c.-401G>C	upstream_gene_variant	0.95	rifampicin
mtrA	3627020	c.330G>A	synonymous_variant	0.96	bedaquiline	Not assoc w R - Interim
mtrA	3627020	c.330G>A	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrA	3627041	c.307_309delATCinsGG	frameshift_variant&missense_variant	0.96	bedaquiline
mtrA	3627041	c.307_309delATCinsGG	frameshift_variant&missense_variant	0.96	rifampicin
mtrB	3627059	c.-446G>A	upstream_gene_variant	0.97	bedaquiline
mtrB	3627059	c.-446G>A	upstream_gene_variant	0.97	rifampicin
mtrA	3627068	c.282T>C	synonymous_variant	0.96	bedaquiline
mtrA	3627068	c.282T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3627071	c.-458G>C	upstream_gene_variant	0.98	bedaquiline
mtrB	3627071	c.-458G>C	upstream_gene_variant	0.98	rifampicin
mtrA	3627080	c.270T>C	synonymous_variant	0.98	bedaquiline
mtrA	3627080	c.270T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.98	bedaquiline
mtrB	3627083	c.-470G>C	upstream_gene_variant	0.98	rifampicin
mtrB	3627092	c.-479C>G	upstream_gene_variant	0.98	bedaquiline
mtrB	3627092	c.-479C>G	upstream_gene_variant	0.98	rifampicin
mtrA	3627098	c.252A>C	synonymous_variant	0.96	bedaquiline
mtrA	3627098	c.252A>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
mtrB	3627101	c.-488C>G	upstream_gene_variant	0.98	bedaquiline
mtrB	3627101	c.-488C>G	upstream_gene_variant	0.98	rifampicin
mtrB	3627104	c.-491C>G	upstream_gene_variant	0.98	bedaquiline
mtrB	3627104	c.-491C>G	upstream_gene_variant	0.98	rifampicin
mtrA	3627119	c.231T>G	synonymous_variant	0.98	bedaquiline
mtrA	3627119	c.231T>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
mtrB	3627125	c.-512C>G	upstream_gene_variant	0.98	bedaquiline
mtrB	3627125	c.-512C>G	upstream_gene_variant	0.98	rifampicin
mtrB	3627131	c.-518C>G	upstream_gene_variant	0.98	bedaquiline
mtrB	3627131	c.-518C>G	upstream_gene_variant	0.98	rifampicin
mtrB	3627139	c.-526T>C	upstream_gene_variant	0.98	bedaquiline
mtrB	3627139	c.-526T>C	upstream_gene_variant	0.98	rifampicin
mtrB	3627143	c.-530G>T	upstream_gene_variant	0.98	bedaquiline
mtrB	3627143	c.-530G>T	upstream_gene_variant	0.98	rifampicin
mtrB	3627167	c.-554T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627167	c.-554T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627173	c.-560G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627173	c.-560G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627182	c.-569T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627182	c.-569T>C	upstream_gene_variant	1.0	rifampicin
mtrA	3627185	c.163_165delTTGinsCC	frameshift_variant&missense_variant	1.0	bedaquiline
mtrA	3627185	c.163_165delTTGinsCC	frameshift_variant&missense_variant	1.0	rifampicin
mtrA	3627188	c.162A>G	synonymous_variant	1.0	bedaquiline
mtrA	3627188	c.162A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3627203	c.-590C>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627203	c.-590C>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627206	c.-593G>A	upstream_gene_variant	1.0	bedaquiline
mtrB	3627206	c.-593G>A	upstream_gene_variant	1.0	rifampicin
mtrB	3627209	c.-596G>A	upstream_gene_variant	1.0	bedaquiline
mtrB	3627209	c.-596G>A	upstream_gene_variant	1.0	rifampicin
mtrB	3627212	c.-599C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627212	c.-599C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627215	c.-602G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627215	c.-602G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627224	c.-611G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627224	c.-611G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627227	c.-614T>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627227	c.-614T>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627233	c.-620T>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627233	c.-620T>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627236	c.-623T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627236	c.-623T>C	upstream_gene_variant	1.0	rifampicin
mtrA	3627242	c.108C>T	synonymous_variant	1.0	bedaquiline
mtrA	3627242	c.108C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3627263	c.-650C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627263	c.-650C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627266	c.-653A>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627266	c.-653A>G	upstream_gene_variant	1.0	rifampicin
mtrA	3627269	c.81G>A	synonymous_variant	1.0	bedaquiline	Not assoc w R - Interim
mtrA	3627269	c.81G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
mtrB	3627272	c.-659G>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627272	c.-659G>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627296	c.-683T>G	upstream_gene_variant	1.0	bedaquiline
mtrB	3627296	c.-683T>G	upstream_gene_variant	1.0	rifampicin
mtrB	3627301	c.-688T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627301	c.-688T>C	upstream_gene_variant	1.0	rifampicin
mtrA	3627305	c.43_45delGCTinsCG	frameshift_variant&synonymous_variant	1.0	bedaquiline
mtrA	3627305	c.43_45delGCTinsCG	frameshift_variant&synonymous_variant	1.0	rifampicin
mtrB	3627308	c.-695C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627308	c.-695C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627317	c.-704T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627317	c.-704T>C	upstream_gene_variant	1.0	rifampicin
mtrB	3627320	c.-707C>T	upstream_gene_variant	1.0	bedaquiline
mtrB	3627320	c.-707C>T	upstream_gene_variant	1.0	rifampicin
mtrB	3627325	c.-712T>C	upstream_gene_variant	1.0	bedaquiline
mtrB	3627325	c.-712T>C	upstream_gene_variant	1.0	rifampicin
rpoA	3877587	c.921A>G	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoA	3877613	p.Ile299Val	missense_variant	0.97	rifampicin
rpoA	3877638	c.870T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877656	c.852T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877668	c.840A>G	synonymous_variant	1.0	rifampicin
rpoA	3877671	c.837C>G	synonymous_variant	1.0	rifampicin
rpoA	3877677	c.831G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877680	c.828G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877686	c.822A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877695	c.813C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877704	c.804G>C	synonymous_variant	0.98	rifampicin
rpoA	3877728	c.780C>G	synonymous_variant	0.98	rifampicin
rpoA	3877740	c.768G>C	synonymous_variant	0.98	rifampicin
rpoA	3877743	c.765T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877764	c.744C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877776	c.732T>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877794	c.714G>T	synonymous_variant	0.98	rifampicin
rpoA	3877818	c.690A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877848	c.660C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877856	c.652T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877857	c.651G>A	synonymous_variant	1.0	rifampicin
rpoA	3877866	c.642G>C	synonymous_variant	1.0	rifampicin
rpoA	3877872	c.636C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877875	c.633T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877896	c.612G>C	synonymous_variant	1.0	rifampicin
rpoA	3877905	c.603A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877908	c.600T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3877920	c.588G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoA	3877926	c.582G>C	synonymous_variant	0.98	rifampicin
rpoA	3877962	c.546G>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoA	3877971	p.Asp179Glu	missense_variant	0.96	rifampicin	Uncertain significance
rpoA	3877986	c.522G>C	synonymous_variant	0.95	rifampicin
rpoA	3877989	c.519A>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoA	3878001	c.505_507delTCAinsAGC	synonymous_variant	0.93	rifampicin
rpoA	3878019	c.489A>G	synonymous_variant	0.92	rifampicin
rpoA	3878022	c.486T>C	synonymous_variant	0.91	rifampicin
rpoA	3878028	c.480G>C	synonymous_variant	0.91	rifampicin
rpoA	3878031	c.477T>C	synonymous_variant	0.91	rifampicin
rpoA	3878034	c.474A>G	synonymous_variant	0.91	rifampicin
rpoA	3878040	c.468T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoA	3878046	c.462T>C	synonymous_variant	0.91	rifampicin
rpoA	3878050	p.Arg153Lys	missense_variant	0.91	rifampicin
rpoA	3878055	c.453A>G	synonymous_variant	0.91	rifampicin
rpoA	3878061	c.447G>C	synonymous_variant	0.92	rifampicin
rpoA	3878064	c.444G>C	synonymous_variant	0.92	rifampicin
rpoA	3878070	c.438T>C	synonymous_variant	0.93	rifampicin
rpoA	3878082	c.426T>C	synonymous_variant	0.94	rifampicin
rpoA	3878103	c.405A>G	synonymous_variant	0.96	rifampicin
rpoA	3878106	c.402G>C	synonymous_variant	0.96	rifampicin
rpoA	3878118	c.390T>C	synonymous_variant	0.96	rifampicin
rpoA	3878124	c.384G>C	synonymous_variant	0.96	rifampicin
rpoA	3878127	c.381G>C	synonymous_variant	0.96	rifampicin
rpoA	3878143	p.Gly122Asp	missense_variant	0.96	rifampicin	Uncertain significance
rpoA	3878160	c.348C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoA	3878172	c.336G>C	synonymous_variant	0.94	rifampicin
rpoA	3878187	c.321C>G	synonymous_variant	0.95	rifampicin
rpoA	3878193	c.315T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878205	c.303T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878217	c.291A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878247	c.261G>C	synonymous_variant	0.96	rifampicin
rpoA	3878253	c.255G>C	synonymous_variant	0.96	rifampicin
rpoA	3878256	c.252G>C	synonymous_variant	0.96	rifampicin
rpoA	3878264	p.Ser82Gly	missense_variant	0.96	rifampicin
rpoA	3878271	c.237T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoA	3878274	c.234G>C	synonymous_variant	0.95	rifampicin
rpoA	3878283	p.Glu75Asp	missense_variant	0.97	rifampicin	Uncertain significance
rpoA	3878292	c.216T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoA	3878298	c.210A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoA	3878301	c.207C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878310	c.198G>C	synonymous_variant	1.0	rifampicin
rpoA	3878313	c.195G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878322	c.186A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878331	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878334	c.174T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878337	c.171T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoA	3878346	c.162T>C	synonymous_variant	1.0	rifampicin
rpoA	3878358	c.150C>A	synonymous_variant	1.0	rifampicin
rpoA	3878364	c.144A>C	synonymous_variant	0.91	rifampicin
rpoA	3878843	c.-337_-336delCGinsAA	upstream_gene_variant	1.0	rifampicin
rpoA	3878845	c.-338G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878853	c.-346G>A	upstream_gene_variant	1.0	rifampicin
rpoA	3878878	c.-371T>C	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878886	c.-379G>A	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878889	c.-382A>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878890	c.-383C>G	upstream_gene_variant	1.0	rifampicin
rpoA	3878893	c.-388_-386delCACinsAG	upstream_gene_variant	1.0	rifampicin
rpoA	3878896	c.-389G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878908	c.-403_-401delAACinsCTG	upstream_gene_variant	1.0	rifampicin
rpoA	3878914	c.-407T>C	upstream_gene_variant	1.0	rifampicin	Uncertain significance
rpoA	3878917	c.-410G>C	upstream_gene_variant	1.0	rifampicin
rpoA	3878938	c.-431T>C	upstream_gene_variant	0.93	rifampicin
rpoA	3878942	c.-436_-435delATinsCA	upstream_gene_variant	0.93	rifampicin
rpoA	3878944	c.-437G>T	upstream_gene_variant	0.93	rifampicin
rpoA	3878947	c.-440G>C	upstream_gene_variant	0.93	rifampicin	Uncertain significance
rpoA	3878968	c.-461T>C	upstream_gene_variant	0.92	rifampicin	Uncertain significance
ddn	3986615	c.-229C>T	upstream_gene_variant	1.0	delamanid
ddn	3986615	c.-229C>T	upstream_gene_variant	1.0	pretomanid
ddn	3986636	c.-208C>G	upstream_gene_variant	1.0	delamanid
ddn	3986636	c.-208C>G	upstream_gene_variant	1.0	pretomanid
ddn	3986645	c.-199G>A	upstream_gene_variant	0.97	delamanid
ddn	3986645	c.-199G>A	upstream_gene_variant	0.97	pretomanid
ddn	3986661	c.-183C>A	upstream_gene_variant	0.96	delamanid
ddn	3986661	c.-183C>A	upstream_gene_variant	0.96	pretomanid
ddn	3986667	c.-177_-175delCTCinsACG	upstream_gene_variant	0.96	delamanid
ddn	3986667	c.-177_-175delCTCinsACG	upstream_gene_variant	0.96	pretomanid
ddn	3986687	c.-157C>T	upstream_gene_variant	0.94	delamanid
ddn	3986687	c.-157C>T	upstream_gene_variant	0.94	pretomanid
ddn	3986690	c.-154C>G	upstream_gene_variant	0.94	delamanid
ddn	3986690	c.-154C>G	upstream_gene_variant	0.94	pretomanid
ddn	3986696	c.-148G>C	upstream_gene_variant	0.88	delamanid
ddn	3986696	c.-148G>C	upstream_gene_variant	0.88	pretomanid
ddn	3986699	c.-145C>G	upstream_gene_variant	0.88	delamanid
ddn	3986699	c.-145C>G	upstream_gene_variant	0.88	pretomanid
ddn	3986714	c.-130C>G	upstream_gene_variant	0.86	delamanid
ddn	3986714	c.-130C>G	upstream_gene_variant	0.86	pretomanid
clpC1	4038335	c.2370C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038350	c.2355C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038356	c.2349T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038359	c.2346A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038368	c.2337T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038383	c.2322G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038388	c.2317T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038392	c.2313C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038398	c.2307G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038403	c.2302T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4038407	c.2298G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038416	c.2289C>G	synonymous_variant	1.0	pyrazinamide
clpC1	4038419	c.2286T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038428	c.2277G>T	synonymous_variant	1.0	pyrazinamide
clpC1	4038435	p.Ala757Gln	missense_variant	1.0	pyrazinamide
clpC1	4038444	p.Ala754Lys	missense_variant	0.97	pyrazinamide
clpC1	4038446	c.2259T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038449	c.2256C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4038456	p.Val750Glu	missense_variant	0.95	pyrazinamide
clpC1	4038461	c.2244G>T	synonymous_variant	0.95	pyrazinamide
clpC1	4038485	p.Gly740Glu	missense_variant	0.95	pyrazinamide
clpC1	4038497	c.2206_2208delAGCinsGA	frameshift_variant&missense_variant	0.95	pyrazinamide
clpC1	4038521	c.2182_2184delATCinsGG	frameshift_variant&missense_variant	0.95	pyrazinamide
clpC1	4038530	p.Glu725Asp	missense_variant	0.95	pyrazinamide
clpC1	4038533	p.Arg724Gln	missense_variant	0.95	pyrazinamide
clpC1	4038587	c.2118C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038596	c.2109A>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038602	c.2103G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038605	c.2100G>A	synonymous_variant	0.98	pyrazinamide
clpC1	4038613	p.Asn698His	missense_variant	0.98	pyrazinamide
clpC1	4038614	c.2091C>T	synonymous_variant	0.98	pyrazinamide
clpC1	4038623	c.2082A>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038647	c.2058T>G	synonymous_variant	0.96	pyrazinamide
clpC1	4038653	c.2052C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4038658	p.Lys683Gln	missense_variant	0.96	pyrazinamide
clpC1	4038661	p.Ser682Thr	missense_variant	0.96	pyrazinamide
clpC1	4038662	c.2043T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038671	c.2034T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038679	p.Pro676Ala	missense_variant	0.96	pyrazinamide
clpC1	4038683	c.2022T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4038692	p.Ser671Lys	missense_variant	0.97	pyrazinamide
clpC1	4038701	c.2004G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038704	c.2001T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038707	c.1998C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4038713	c.1992T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4038740	c.1965G>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038752	c.1953G>A	synonymous_variant	0.98	pyrazinamide
clpC1	4038773	c.1932T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038779	c.1926C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038782	c.1923G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4038790	c.1915C>T	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4038815	c.1890G>C	synonymous_variant	1.0	pyrazinamide
clpC1	4038878	c.1827A>G	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4038905	c.1800A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4038908	c.1797C>G	synonymous_variant	0.99	pyrazinamide
clpC1	4038914	c.1791G>C	synonymous_variant	0.99	pyrazinamide
clpC1	4038923	c.1782A>G	synonymous_variant	0.99	pyrazinamide
clpC1	4038932	c.1773G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038953	c.1752A>G	synonymous_variant	0.97	pyrazinamide
clpC1	4038956	c.1749T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038965	c.1740T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038971	c.1734T>C	synonymous_variant	0.96	pyrazinamide
clpC1	4038974	c.1731T>G	synonymous_variant	0.96	pyrazinamide
clpC1	4038989	c.1716T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4038997	c.1708T>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4039004	c.1701C>G	synonymous_variant	0.97	pyrazinamide
clpC1	4039022	c.1683A>G	synonymous_variant	0.97	pyrazinamide
clpC1	4039031	c.1674T>G	synonymous_variant	0.97	pyrazinamide
clpC1	4039037	c.1668T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039046	c.1659C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039067	c.1638G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039070	c.1635G>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039073	c.1632C>T	synonymous_variant	0.93	pyrazinamide
clpC1	4039079	c.1626C>G	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4039082	c.1623C>T	synonymous_variant	0.92	pyrazinamide
clpC1	4039085	c.1620A>G	synonymous_variant	0.92	pyrazinamide
clpC1	4039097	c.1608G>T	synonymous_variant	0.93	pyrazinamide
clpC1	4039103	c.1602T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039112	c.1593C>G	synonymous_variant	0.93	pyrazinamide
clpC1	4039121	c.1584T>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039142	c.1563A>G	synonymous_variant	0.92	pyrazinamide
clpC1	4039145	c.1560G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4039169	c.1536A>G	synonymous_variant	0.9	pyrazinamide
clpC1	4039172	c.1533A>G	synonymous_variant	0.9	pyrazinamide
clpC1	4039178	c.1527G>C	synonymous_variant	0.88	pyrazinamide
clpC1	4039183	c.1522T>C	synonymous_variant	0.88	pyrazinamide
clpC1	4039186	c.1519C>T	synonymous_variant	0.89	pyrazinamide
clpC1	4039190	c.1515C>A	synonymous_variant	0.9	pyrazinamide
clpC1	4039199	p.Ala502Glu	missense_variant	0.89	pyrazinamide
clpC1	4039208	c.1497C>G	synonymous_variant	0.88	pyrazinamide
clpC1	4039220	c.1485G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4039235	c.1470C>T	synonymous_variant	0.91	pyrazinamide
clpC1	4039241	c.1464G>C	synonymous_variant	0.91	pyrazinamide
clpC1	4039244	c.1461G>C	synonymous_variant	0.9	pyrazinamide
clpC1	4039274	c.1431G>C	synonymous_variant	0.9	pyrazinamide	Not assoc w R - Interim
clpC1	4039286	c.1419T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039292	c.1413C>T	synonymous_variant	0.93	pyrazinamide
clpC1	4039295	c.1410A>G	synonymous_variant	0.93	pyrazinamide
clpC1	4039298	c.1407T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039310	c.1395A>G	synonymous_variant	0.92	pyrazinamide
clpC1	4039319	c.1386T>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4039328	c.1377A>T	synonymous_variant	0.94	pyrazinamide
clpC1	4039337	p.Thr456Gln	missense_variant	0.91	pyrazinamide
clpC1	4039347	p.Arg453Gln	missense_variant	0.91	pyrazinamide	Uncertain significance
clpC1	4039349	c.1356C>T	synonymous_variant	0.91	pyrazinamide
clpC1	4039352	c.1353C>G	synonymous_variant	0.88	pyrazinamide
clpC1	4039360	p.Ser449Arg	missense_variant	0.89	pyrazinamide
clpC1	4039361	c.1344C>G	synonymous_variant	0.89	pyrazinamide
clpC1	4039382	c.1323C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039391	c.1314T>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039394	c.1311G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039397	c.1308A>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039406	c.1299G>T	synonymous_variant	0.91	pyrazinamide
clpC1	4039409	c.1296T>C	synonymous_variant	0.91	pyrazinamide
clpC1	4039412	c.1293T>C	synonymous_variant	0.91	pyrazinamide
clpC1	4039415	p.Glu430Asp	missense_variant	0.91	pyrazinamide	Uncertain significance
clpC1	4039430	c.1275T>C	synonymous_variant	0.88	pyrazinamide
clpC1	4039439	c.1266C>G	synonymous_variant	0.88	pyrazinamide
clpC1	4039442	c.1263A>G	synonymous_variant	0.88	pyrazinamide
clpC1	4039445	c.1260C>T	synonymous_variant	0.85	pyrazinamide
clpC1	4039448	c.1257A>T	synonymous_variant	0.85	pyrazinamide
clpC1	4039454	c.1251A>G	synonymous_variant	0.85	pyrazinamide	Not assoc w R - Interim
clpC1	4039463	c.1242C>G	synonymous_variant	0.83	pyrazinamide
clpC1	4039466	c.1239T>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039469	c.1236T>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039481	c.1224T>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039484	c.1221T>C	synonymous_variant	0.83	pyrazinamide
clpC1	4039487	c.1218G>C	synonymous_variant	0.88	pyrazinamide
clpC1	4039517	c.1188C>G	synonymous_variant	0.91	pyrazinamide
clpC1	4039553	c.1152C>A	synonymous_variant	0.88	pyrazinamide
clpC1	4039556	c.1149G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4039559	c.1146C>G	synonymous_variant	0.92	pyrazinamide
clpC1	4039562	c.1143C>G	synonymous_variant	0.92	pyrazinamide
clpC1	4039565	c.1140G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4039570	p.Met379Val	missense_variant	0.92	pyrazinamide
clpC1	4039571	c.1134G>C	synonymous_variant	0.88	pyrazinamide
clpC1	4039574	p.Ala377Gly	missense_variant	0.88	pyrazinamide
clpC1	4039577	c.1128T>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4039589	c.1116G>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039601	c.1104G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039607	c.1098C>T	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
clpC1	4039610	c.1095G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039616	c.1089G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039622	c.1083C>A	synonymous_variant	0.98	pyrazinamide
clpC1	4039646	c.1059G>A	synonymous_variant	0.95	pyrazinamide
clpC1	4039661	c.1044T>G	synonymous_variant	0.97	pyrazinamide
clpC1	4039664	c.1041G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039691	c.1014G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039694	c.1011G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039724	c.981A>G	synonymous_variant	0.98	pyrazinamide
clpC1	4039748	c.957G>A	synonymous_variant	0.95	pyrazinamide
clpC1	4039751	c.954A>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039757	c.948A>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039760	c.945T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039766	c.939T>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039769	c.936C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039778	c.927A>G	synonymous_variant	0.94	pyrazinamide
clpC1	4039781	c.924G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4039787	c.916_918delTCGinsAGC	synonymous_variant	0.97	pyrazinamide
clpC1	4039802	c.903G>C	synonymous_variant	0.92	pyrazinamide
clpC1	4039805	c.900C>T	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4039808	c.897G>A	synonymous_variant	0.92	pyrazinamide
clpC1	4039817	c.888A>T	synonymous_variant	0.93	pyrazinamide
clpC1	4039820	c.885T>G	synonymous_variant	0.93	pyrazinamide
clpC1	4039831	c.874T>C	synonymous_variant	0.93	pyrazinamide
clpC1	4039832	c.873C>G	synonymous_variant	0.93	pyrazinamide
clpC1	4039850	c.855T>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039865	c.840T>C	synonymous_variant	0.94	pyrazinamide
clpC1	4039898	c.807C>G	synonymous_variant	0.96	pyrazinamide
clpC1	4039904	c.801A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4039925	c.780C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4039931	c.774T>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039934	c.771G>C	synonymous_variant	0.95	pyrazinamide
clpC1	4039946	c.759A>C	synonymous_variant	0.96	pyrazinamide
clpC1	4039949	c.756G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039955	c.750G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4039979	c.726C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4040015	c.690G>A	synonymous_variant	0.96	pyrazinamide	Not assoc w R - Interim
clpC1	4040018	c.687G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4040021	c.684A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040024	c.681A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040039	c.666G>A	synonymous_variant	0.95	pyrazinamide
clpC1	4040090	c.613_615delTCTinsAGC	synonymous_variant	0.94	pyrazinamide
clpC1	4040093	c.612C>G	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
clpC1	4040105	c.600C>G	synonymous_variant	0.95	pyrazinamide
clpC1	4040144	c.561G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4040147	c.558A>G	synonymous_variant	0.96	pyrazinamide	Not assoc w R - Interim
clpC1	4040153	c.552A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040162	c.543G>C	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
clpC1	4040165	c.540G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4040168	c.537G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4040171	c.534C>G	synonymous_variant	0.91	pyrazinamide
clpC1	4040180	c.525C>T	synonymous_variant	0.93	pyrazinamide
clpC1	4040200	c.505T>C	synonymous_variant	0.94	pyrazinamide
clpC1	4040201	c.504C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4040207	c.498T>G	synonymous_variant	0.94	pyrazinamide
clpC1	4040210	c.495G>C	synonymous_variant	0.94	pyrazinamide
clpC1	4040213	c.492T>A	synonymous_variant	0.94	pyrazinamide
clpC1	4040225	c.480A>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040228	c.477G>A	synonymous_variant	0.96	pyrazinamide
clpC1	4040237	c.468C>T	synonymous_variant	0.94	pyrazinamide
clpC1	4040243	c.462C>T	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
clpC1	4040249	c.456A>G	synonymous_variant	0.94	pyrazinamide
clpC1	4040257	p.Ala150Thr	missense_variant	0.93	pyrazinamide
clpC1	4040267	c.438A>G	synonymous_variant	0.93	pyrazinamide	Not assoc w R - Interim
clpC1	4040273	c.432T>A	synonymous_variant	0.89	pyrazinamide
clpC1	4040277	c.427_428delTCinsAG	synonymous_variant	0.88	pyrazinamide
clpC1	4040279	c.426C>G	synonymous_variant	0.88	pyrazinamide	Not assoc w R - Interim
clpC1	4040291	c.414G>C	synonymous_variant	0.91	pyrazinamide
clpC1	4040300	c.405C>T	synonymous_variant	0.92	pyrazinamide
clpC1	4040330	c.375C>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040335	c.370C>T	synonymous_variant	0.96	pyrazinamide
clpC1	4040345	c.360C>G	synonymous_variant	0.98	pyrazinamide
clpC1	4040348	c.357G>C	synonymous_variant	0.98	pyrazinamide
clpC1	4040357	c.348T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040363	c.342A>T	synonymous_variant	0.97	pyrazinamide
clpC1	4040369	c.334_336delCTCinsTG	frameshift_variant&synonymous_variant	0.97	pyrazinamide
clpC1	4040372	c.333C>G	synonymous_variant	0.96	pyrazinamide
clpC1	4040375	c.330G>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040380	c.325T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040381	c.324T>C	synonymous_variant	1.0	pyrazinamide
clpC1	4040387	c.318A>G	synonymous_variant	1.0	pyrazinamide
clpC1	4040393	c.312G>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
clpC1	4040411	c.294T>C	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4040423	c.282A>G	synonymous_variant	0.98	pyrazinamide	Not assoc w R - Interim
clpC1	4040426	c.279T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040431	c.274T>C	synonymous_variant	0.97	pyrazinamide
clpC1	4040441	c.264C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4040444	c.261C>G	synonymous_variant	0.94	pyrazinamide
clpC1	4040450	c.255A>G	synonymous_variant	0.93	pyrazinamide	Not assoc w R - Interim
clpC1	4040459	c.246C>G	synonymous_variant	0.88	pyrazinamide
clpC1	4040465	c.240T>C	synonymous_variant	0.92	pyrazinamide
clpC1	4040471	c.234T>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
clpC1	4040480	c.225T>C	synonymous_variant	0.93	pyrazinamide	Not assoc w R - Interim
clpC1	4040522	c.183T>C	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
clpC1	4040531	c.174T>C	synonymous_variant	0.88	pyrazinamide
clpC1	4040546	c.159G>C	synonymous_variant	0.88	pyrazinamide
clpC1	4040551	c.154T>C	synonymous_variant	0.88	pyrazinamide	Not assoc w R - Interim
clpC1	4040552	c.153G>A	synonymous_variant	0.87	pyrazinamide
clpC1	4040561	c.144A>G	synonymous_variant	0.9	pyrazinamide
clpC1	4040570	c.135C>G	synonymous_variant	0.88	pyrazinamide
clpC1	4040573	c.132T>G	synonymous_variant	0.88	pyrazinamide
clpC1	4040579	c.126A>G	synonymous_variant	0.81	pyrazinamide
clpC1	4040582	c.123G>C	synonymous_variant	0.8	pyrazinamide	Not assoc w R - Interim
clpC1	4040585	c.120A>G	synonymous_variant	0.8	pyrazinamide
clpC1	4040588	c.117T>C	synonymous_variant	0.8	pyrazinamide
clpC1	4040591	c.114C>T	synonymous_variant	0.86	pyrazinamide
clpC1	4040594	c.111G>T	synonymous_variant	0.86	pyrazinamide
clpC1	4040597	c.108C>A	synonymous_variant	0.86	pyrazinamide
clpC1	4040600	c.105A>G	synonymous_variant	0.86	pyrazinamide
clpC1	4040603	c.102T>C	synonymous_variant	0.86	pyrazinamide	Not assoc w R - Interim
clpC1	4040606	c.99T>C	synonymous_variant	0.86	pyrazinamide
glpK	4138451	c.1305T>C	synonymous_variant	0.93	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138457	c.1299C>T	synonymous_variant	0.93	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138464	p.Gly431Ala	missense_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138472	c.1284G>C	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138478	c.1278T>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138481	c.1275G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138487	c.1267_1269delTTGinsCC	frameshift_variant&missense_variant	1.0	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
glpK	4138495	p.Gln421Glu	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138498	p.Leu420Met	missense_variant	1.0	ethambutol	Uncertain significance
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
glpK	4138500	p.Arg419His	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138502	c.1254T>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138505	c.1251T>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138514	c.1242A>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138523	c.1233C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138529	c.1227G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138532	c.1224G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138535	c.1221T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138541	c.1215C>T	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin	Not assoc w R - Interim
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138568	c.1188A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138574	c.1182G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138580	c.1176C>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138596	p.Phe387Tyr	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138606	c.1150T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138631	c.1125C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138634	c.1122G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138643	c.1113A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4138646	c.1110G>A	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138661	c.1095T>C	synonymous_variant	0.97	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138664	c.1092G>T	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138681	p.Met359Val	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138696	p.Pro354Ala	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138702	p.Gln352Glu	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138703	c.1053C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138706	c.1050C>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138718	c.1038T>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138721	p.Gln345His	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138724	c.1032A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138731	p.Gly342Asp	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138734	p.Ser341Pro	missense_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138745	c.1011G>C	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4138757	c.999A>G	synonymous_variant	1.0	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139312	c.444T>C	synonymous_variant	0.92	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139321	c.435T>G	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139324	c.432A>C	synonymous_variant	0.93	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139327	c.429G>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139336	c.420C>T	synonymous_variant	0.95	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4139356	p.Leu134Val	missense_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139359	p.Asn133Asp	missense_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139360	c.396A>T	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139363	c.393T>C	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139366	c.390T>C	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139372	c.384A>C	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139375	p.Asp127Glu	missense_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139380	c.376C>T	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139381	c.375G>C	synonymous_variant	0.89	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139387	c.369G>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139399	c.357C>G	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139408	c.348T>C	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139417	c.339A>G	synonymous_variant	0.94	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139420	c.336T>C	synonymous_variant	0.94	ethambutol	Not assoc w R - Interim
					moxifloxacin	Not assoc w R - Interim
					streptomycin	Not assoc w R - Interim
					levofloxacin	Not assoc w R - Interim
					rifampicin	Not assoc w R - Interim
					isoniazid	Not assoc w R - Interim
glpK	4139588	c.168G>C	synonymous_variant	0.82	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139601	p.Arg52Lys	missense_variant	0.82	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139603	c.153C>G	synonymous_variant	0.82	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139630	c.126C>T	synonymous_variant	0.83	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139637	p.Ala40Gly	missense_variant	0.82	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139639	c.115_117delGTGinsAC	frameshift_variant&missense_variant	0.9	ethambutol	Uncertain significance
					moxifloxacin	Uncertain significance
					streptomycin	Uncertain significance
					levofloxacin	Uncertain significance
					rifampicin	Uncertain significance
					isoniazid	Uncertain significance
glpK	4139646	c.109_110insGCG	conservative_inframe_insertion	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139654	c.99_101delTCA	disruptive_inframe_deletion	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
glpK	4139699	c.57C>G	synonymous_variant	0.9	ethambutol
					moxifloxacin
					streptomycin
					levofloxacin
					rifampicin
					isoniazid
embC	4240717	c.855T>C	synonymous_variant	1.0	ethambutol
embC	4240726	c.864G>C	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embC	4240736	p.Ser292Ala	missense_variant	1.0	ethambutol
embC	4240766	c.904C>A	synonymous_variant	1.0	ethambutol
embC	4240774	c.912C>G	synonymous_variant	1.0	ethambutol
embC	4240780	c.918T>C	synonymous_variant	1.0	ethambutol
embC	4240783	c.921G>C	synonymous_variant	1.0	ethambutol
embC	4240789	c.927T>C	synonymous_variant	1.0	ethambutol
embC	4240807	c.945C>G	synonymous_variant	0.97	ethambutol	Not assoc w R - Interim
embC	4240819	c.957A>C	synonymous_variant	0.97	ethambutol
embC	4240828	c.966G>C	synonymous_variant	0.97	ethambutol
embC	4240831	c.969T>G	synonymous_variant	0.97	ethambutol
embC	4240859	c.997C>T	synonymous_variant	0.94	ethambutol
embC	4241086	c.1224G>C	synonymous_variant	0.94	ethambutol
embC	4241104	c.1242G>A	synonymous_variant	0.9	ethambutol	Not assoc w R - Interim
embC	4241107	c.1245G>C	synonymous_variant	0.9	ethambutol
embC	4241109	p.Ala416Gly	missense_variant	0.9	ethambutol
embC	4241123	c.1261C>A	synonymous_variant	0.9	ethambutol
embC	4241167	c.1305C>G	synonymous_variant	0.88	ethambutol
embC	4241179	c.1317G>C	synonymous_variant	0.83	ethambutol
embC	4241195	p.Ser445Ala	missense_variant	0.89	ethambutol
embC	4241198	p.Ile446Val	missense_variant	0.94	ethambutol
embC	4241218	c.1356G>C	synonymous_variant	0.92	ethambutol
embC	4241219	p.Ile453Val	missense_variant	0.91	ethambutol
embB	4247401	c.888T>C	synonymous_variant	0.85	ethambutol
embB	4247425	c.912G>C	synonymous_variant	0.89	ethambutol
embB	4247437	c.924A>G	synonymous_variant	0.9	ethambutol	Not assoc w R - Interim
embB	4247440	c.927C>G	synonymous_variant	0.9	ethambutol
embB	4247464	c.951C>G	synonymous_variant	0.95	ethambutol
embB	4247470	c.957T>C	synonymous_variant	0.95	ethambutol
embB	4247491	c.978G>C	synonymous_variant	0.94	ethambutol
embB	4247497	c.984T>C	synonymous_variant	0.94	ethambutol
embB	4247500	c.987C>G	synonymous_variant	0.94	ethambutol
embB	4247512	c.999T>C	synonymous_variant	0.89	ethambutol
embB	4247528	p.Leu339Met	missense_variant	0.77	ethambutol
embB	4247537	p.His342Ser	missense_variant	0.73	ethambutol
embB	4248118	c.1605T>G	synonymous_variant	1.0	ethambutol
embB	4248133	c.1620C>G	synonymous_variant	1.0	ethambutol
embB	4248139	c.1626C>G	synonymous_variant	1.0	ethambutol
embB	4248142	c.1629T>C	synonymous_variant	1.0	ethambutol
embB	4248143	c.1630T>C	synonymous_variant	1.0	ethambutol
embB	4248157	c.1644A>G	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4248159	p.Cys549Ser	missense_variant	1.0	ethambutol
embB	4248167	p.Thr552Val	missense_variant	1.0	ethambutol
embB	4248170	p.Ala553Ser	missense_variant	1.0	ethambutol
embB	4248173	p.Val554Met	missense_variant	1.0	ethambutol
embB	4248185	p.Leu558Met	missense_variant	1.0	ethambutol
embB	4248190	c.1677G>C	synonymous_variant	0.96	ethambutol	Not assoc w R - Interim
embB	4248206	c.1693_1695delAGCinsGT	frameshift_variant&missense_variant	1.0	ethambutol
embB	4248214	c.1701C>G	synonymous_variant	1.0	ethambutol
embB	4248217	c.1704C>G	synonymous_variant	1.0	ethambutol
embB	4248220	c.1707A>C	synonymous_variant	1.0	ethambutol
embB	4248226	c.1713G>A	synonymous_variant	1.0	ethambutol	Not assoc w R - Interim
embB	4248256	c.1743C>G	synonymous_variant	1.0	ethambutol
embB	4248259	p.Met582Ile	missense_variant	1.0	ethambutol
embB	4248277	c.1764G>C	synonymous_variant	1.0	ethambutol
embB	4248280	c.1767C>G	synonymous_variant	1.0	ethambutol
embB	4248316	c.1803C>G	synonymous_variant	1.0	ethambutol
embB	4248319	c.1806A>G	synonymous_variant	1.0	ethambutol
embB	4248322	c.1809G>C	synonymous_variant	1.0	ethambutol
embB	4248328	c.1815G>C	synonymous_variant	1.0	ethambutol
embB	4248334	c.1821C>G	synonymous_variant	1.0	ethambutol
aftB	4269164	c.-328T>C	upstream_gene_variant	1.0	ethambutol
aftB	4269171	c.-335C>G	upstream_gene_variant	1.0	ethambutol