TB-Profiler result

Run: ERR4769521

Summary

Run ID: ERR4769521

Sample name:

Date: 2024-04-16T09:49:55.071572

Number of reads: 601911

Percentage reads mapped: 15.86

Median coverage: 3.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: RR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.94
lineage4.9 Euro-American (H37Rv-like) None 0.94
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid
ethambutol embB p.Asp311Gly Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.205_207delCTGinsGC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.1132_1134delGCGinsTC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1135_1137delGCGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1189_1191delAAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 0.98 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490987 c.205_207delCTGinsGC frameshift_variant&missense_variant 0.98 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 0.79 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1304062 c.1132_1134delGCGinsTC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304065 c.1135_1137delGCGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304119 c.1189_1191delAAAinsCG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247445 p.Asp311Gly missense_variant 0.9 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 660 c.660G>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 672 c.672T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 690 c.690G>C synonymous_variant 0.91 isoniazid
dnaA 693 c.693A>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 0.94 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.94 isoniazid
dnaA 714 c.714C>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 741 c.741T>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 744 c.744C>T synonymous_variant 0.93 isoniazid
dnaA 747 c.747G>C synonymous_variant 0.94 isoniazid
dnaA 750 c.750C>G synonymous_variant 0.94 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.93 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.92 isoniazid
dnaA 769 c.769_771delGCAinsTC frameshift_variant&missense_variant 0.91 isoniazid Uncertain significance
dnaA 777 c.777A>G synonymous_variant 0.93 isoniazid
dnaA 793 c.793_795delGTAinsAC frameshift_variant&missense_variant 0.91 isoniazid Uncertain significance
dnaA 805 c.805T>C synonymous_variant 0.93 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.92 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.91 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.91 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.91 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 0.89 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.91 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 877 c.877T>C synonymous_variant 0.96 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.96 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.96 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.98 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.98 isoniazid
dnaA 918 c.918C>G synonymous_variant 1.0 isoniazid
dnaA 921 c.921A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 1.0 isoniazid
dnaA 933 c.933C>G synonymous_variant 1.0 isoniazid
dnaA 955 c.955_957delAGAinsCG frameshift_variant&synonymous_variant 1.0 isoniazid Uncertain significance
dnaA 963 c.963C>G synonymous_variant 1.0 isoniazid
dnaA 966 c.966T>C synonymous_variant 1.0 isoniazid
dnaA 975 c.975G>C synonymous_variant 1.0 isoniazid
dnaA 976 c.976C>T synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.97 isoniazid
dnaA 993 c.993A>G synonymous_variant 0.97 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.97 isoniazid
dnaA 1002 c.1002G>A synonymous_variant 0.97 isoniazid
dnaA 1014 c.1014C>G synonymous_variant 0.97 isoniazid
dnaA 1020 c.1020C>G synonymous_variant 0.97 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.96 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.95 isoniazid
dnaA 1038 c.1038A>G synonymous_variant 0.94 isoniazid
dnaA 1047 p.Glu349Asp missense_variant 0.9 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.9 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.9 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 0.9 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.95 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.95 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.96 isoniazid
dnaA 1113 c.1113A>G synonymous_variant 0.96 isoniazid
dnaA 1128 c.1128G>C synonymous_variant 0.98 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 1.0 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>C synonymous_variant 1.0 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1173 c.1174_1177delAAAG frameshift_variant 1.0 isoniazid Uncertain significance
dnaA 1179 c.1179_1180insGTCA frameshift_variant 1.0 isoniazid Uncertain significance
dnaA 1191 c.1191T>C synonymous_variant 0.98 isoniazid
dnaA 1194 c.1194G>C synonymous_variant 0.98 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.98 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.98 isoniazid
dnaA 1210 p.Ala404Ser missense_variant 0.98 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.95 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.95 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.96 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.95 isoniazid
dnaA 1243 p.Thr415Ala missense_variant 0.95 isoniazid Uncertain significance
dnaA 1254 c.1254T>C synonymous_variant 0.93 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.91 isoniazid
gyrB 6178 c.939C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 6208 c.969G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6214 c.975G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGC synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6325 c.-977C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6397 c.1158G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6398 p.Val387Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6416 p.Thr393Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6440 p.Thr401Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6445 p.Asp402Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6452 p.Val405Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6472 c.-830G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6475 c.-827C>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6478 c.-824G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6484 c.-818A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6487 c.1248C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6490 c.-812T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6496 c.-806G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6499 c.-803A>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6508 c.-794A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6511 c.-791A>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6550 c.-752A>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6551 c.1312T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6604 c.-698G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6608 p.Val457Ile missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6763 c.-539G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Ser missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.96 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6860 p.Ser541Ala missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 6869 c.-433T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6872 c.-430T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6896 p.Arg553Lys missense_variant 0.99 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6922 c.1683G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6924 p.Phe562Tyr missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6940 c.-362G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6961 c.-341G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6988 c.-314C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7005 p.Gly589Ala missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 7015 c.-287G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7511 c.210C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7532 c.231T>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7568 c.267C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7700 c.399G>A synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7710 c.409T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 7748 c.447A>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7758 p.Ile153Val missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7821 c.520C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8121 c.820T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8187 c.886_888delCTGinsAC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.99 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8357 c.1056G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 c.1101C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8405 c.1104C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8546 c.1245T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251_1254delCCGGinsGC frameshift_variant&synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8559 c.1258_1260delGGAinsAGGGC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 p.Glu429Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8651 c.1350C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8751 p.Ala484Lys missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8767 p.Arg489Lys missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8796 c.1495_1497delATCinsGG frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8900 c.1599G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8903 c.1602T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9206 c.1905C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9207 p.Lys636Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9311 c.2010C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 9455 c.2154T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 9464 c.2163C>A synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9476 c.2175G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9479 c.2178G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9485 c.2184A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9500 c.2199A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9503 c.2202T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9509 c.2208G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
fgd1 490851 c.69A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490853 p.Ala24Gly missense_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490859 p.Ala26Glu missense_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490899 c.117C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>T synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490921 p.Gln47Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490968 c.186C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491010 c.228C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491037 c.255C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 491073 c.291C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491077 p.Asn99Asp missense_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Asp missense_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491187 c.405G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491461 p.Lys227Arg missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491472 c.690A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491487 c.705C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491502 p.Glu240Asp missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491521 c.739C>A synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491655 c.873C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491687 p.Thr302Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575652 p.Arg102Pro missense_variant 0.82 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 0.87 ethionamide
isoniazid
mshA 575665 c.318G>A synonymous_variant 0.89 ethionamide
isoniazid
mshA 575671 c.324G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575683 c.336G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.94 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 0.96 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575770 c.423G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.98 ethionamide
isoniazid
mshA 575842 c.495G>A synonymous_variant 0.96 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.95 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 575911 c.564G>T synonymous_variant 0.92 ethionamide
isoniazid
mshA 575917 p.Asp190Glu missense_variant 0.92 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.92 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575929 c.582C>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 575932 c.585G>A synonymous_variant 0.92 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575956 c.609G>A synonymous_variant 0.91 ethionamide
isoniazid
ccsA 619615 c.-276C>G upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619629 c.-262G>C upstream_gene_variant 0.85 capreomycin
amikacin
kanamycin
ccsA 619648 c.-243C>G upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619657 c.-234C>G upstream_gene_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>T upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>G upstream_gene_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 619696 c.-195C>G upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619697 c.-194_-192delAGGinsCA upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619702 c.-189C>A upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619706 c.-185_-183delGTGinsAC upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619713 c.-178C>T upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619723 c.-168G>C upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619727 c.-164delAinsGC upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619732 c.-158delG upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619746 c.-145A>G upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619762 c.-129C>G upstream_gene_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 619763 c.-128C>T upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619766 c.-125_-123delACGinsGC upstream_gene_variant 0.83 capreomycin
amikacin
kanamycin
ccsA 619774 c.-117C>G upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619783 c.-108C>G upstream_gene_variant 0.82 capreomycin
amikacin
kanamycin
ccsA 619794 c.-97C>A upstream_gene_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620238 c.348G>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620247 p.Leu119Phe missense_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620257 p.Ile123Val missense_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620264 p.Gly125Ala missense_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620268 c.378G>C synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620283 c.393T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620296 p.Pro136Ala missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620311 p.Leu141Val missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620316 c.426G>C synonymous_variant 0.96 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620337 c.447C>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620409 c.519C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620442 c.552G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620670 c.780C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620709 c.819G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620754 c.864G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620758 p.Arg290Lys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620784 c.894C>A synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620793 c.903G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620802 c.912C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
Rv0565c 657596 c.-126G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657620 c.-150C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657635 c.-167_-165delAGCinsTCG upstream_gene_variant 1.0 ethionamide
Rv0565c 657640 c.-170A>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657641 c.-171C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657647 c.-177C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657670 c.-200A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.98 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734505 c.252G>C synonymous_variant 0.97 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.96 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734814 c.561G>C synonymous_variant 0.8 rifampicin
nusG 734820 c.567A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 0.8 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.9 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.9 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.9 rifampicin
nusG 734862 c.609C>G synonymous_variant 0.9 rifampicin
nusG 734863 p.Thr204Ser missense_variant 0.9 rifampicin
rpoB 760139 c.333A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760140 p.Pro112Ser missense_variant 0.92 rifampicin
rpoB 760148 c.342C>T synonymous_variant 0.94 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 760208 p.Ile134Met missense_variant 0.9 rifampicin
rpoB 760212 p.Asn136Ala missense_variant 0.9 rifampicin
rpoB 760215 c.409_411delAACinsGG frameshift_variant&missense_variant 0.9 rifampicin
rpoB 760219 p.Thr138Ser missense_variant 0.9 rifampicin
rpoB 760223 c.417T>C synonymous_variant 0.91 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 0.97 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.97 rifampicin
rpoB 760317 c.511_513delAGCinsTCG synonymous_variant 0.97 rifampicin
rpoB 760328 c.522G>T synonymous_variant 0.97 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760406 c.600G>C synonymous_variant 0.96 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 0.96 rifampicin Uncertain significance
rpoB 760424 c.618C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>G synonymous_variant 0.96 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.96 rifampicin
rpoB 760502 c.696C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.98 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.97 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760551 c.745_746delTCinsAG synonymous_variant 0.97 rifampicin
rpoB 760563 c.757delCinsAT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoB 760566 p.Ser254Ala missense_variant 1.0 rifampicin
rpoB 760567 c.762delG frameshift_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760608 c.802C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 0.95 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 0.94 rifampicin
rpoB 760965 p.Met387Leu missense_variant 0.92 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.92 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.93 rifampicin
rpoB 760997 c.1191G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761087 c.1281C>G synonymous_variant 0.93 rifampicin
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.93 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.93 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.93 rifampicin
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.98 rifampicin
rpoB 761174 c.1368T>C synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.97 rifampicin
rpoB 761217 c.1411_1413delCCGinsGC frameshift_variant&missense_variant 0.94 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.94 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 0.93 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761300 c.1494G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761303 c.1497G>A synonymous_variant 0.89 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.88 rifampicin
rpoB 761357 c.1551G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.95 rifampicin
rpoB 761366 c.1560C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761375 c.1569G>C synonymous_variant 0.95 rifampicin
rpoB 761403 p.His533Tyr missense_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>G synonymous_variant 0.96 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.97 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761627 c.1821C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.94 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.95 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.94 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.95 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 0.94 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.94 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.94 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.93 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 0.9 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAC frameshift_variant&missense_variant 0.89 rifampicin
rpoB 761727 p.Ser641Ala missense_variant 0.89 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.91 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.93 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.91 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.97 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.97 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.97 rifampicin
rpoB 761791 p.Arg662Gln missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.95 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.91 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 0.92 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 0.92 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.92 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>G synonymous_variant 0.92 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.92 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.92 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.92 rifampicin
rpoB 761903 c.2097T>G synonymous_variant 0.93 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.93 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.93 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.93 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.93 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.93 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 0.96 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762017 c.2211A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.98 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762512 c.-858C>G upstream_gene_variant 0.88 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.95 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.94 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoB 762537 c.2731_2733delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 0.9 rifampicin Uncertain significance
rpoB 762786 p.Val994Lys missense_variant 0.9 rifampicin
rpoB 762798 p.Ala998Ser missense_variant 0.93 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762820 p.Phe1005Tyr missense_variant 0.97 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 1.0 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763179 c.-191C>T upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763217 c.-153G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763250 c.-120C>T upstream_gene_variant 1.0 rifampicin
rpoC 763251 c.-119C>T upstream_gene_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 1.0 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 1.0 rifampicin
rpoC 763289 c.-81C>G upstream_gene_variant 1.0 rifampicin
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763396 c.27A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763402 c.33C>G synonymous_variant 1.0 rifampicin
rpoC 763405 c.36C>T synonymous_variant 0.98 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763417 c.48C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763430 c.61A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 1.0 rifampicin
rpoC 763447 c.78C>T synonymous_variant 1.0 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 763711 c.342G>C synonymous_variant 1.0 rifampicin
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>T synonymous_variant 1.0 rifampicin
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Glu missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.99 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.99 rifampicin
rpoC 763822 c.453C>G synonymous_variant 0.99 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.98 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.98 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.98 rifampicin
rpoC 763849 c.480G>A synonymous_variant 0.98 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.96 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.96 rifampicin
rpoC 763867 c.498C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763870 c.501C>T synonymous_variant 0.96 rifampicin
rpoC 763871 p.Gly168Ser missense_variant 0.96 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.96 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.96 rifampicin
rpoC 763888 c.519G>T synonymous_variant 0.95 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.95 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763910 p.Leu181Met missense_variant 0.96 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.95 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.95 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.95 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.96 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.97 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.99 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.98 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.98 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 0.98 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.96 rifampicin
rpoC 764147 c.778_780delTCGinsGC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 0.95 rifampicin
rpoC 764156 p.Lys263Arg missense_variant 0.95 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 0.95 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 0.95 rifampicin
rpoC 764207 p.Val280Thr missense_variant 0.95 rifampicin Uncertain significance
rpoC 764215 c.846A>T synonymous_variant 0.95 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 0.97 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.95 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.95 rifampicin
rpoC 764266 c.897T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764269 c.900G>T synonymous_variant 0.93 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.94 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764285 p.Gly306Ser missense_variant 0.94 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.95 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>G synonymous_variant 0.96 rifampicin
rpoC 764387 c.1018T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.96 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.97 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764452 c.1083T>C synonymous_variant 0.96 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 0.96 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.97 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 0.96 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.95 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 0.96 rifampicin
rpoC 764713 c.1344G>A synonymous_variant 0.96 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.95 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.96 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764857 c.1488G>T synonymous_variant 0.97 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.98 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.98 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.99 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.99 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.99 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.98 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>G synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 1.0 rifampicin
rpoC 765349 c.1980T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765357 p.Met663Thr missense_variant 0.9 rifampicin
rpoC 765359 p.Ala664Thr missense_variant 0.9 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 0.93 rifampicin
rpoC 765397 c.2028G>T synonymous_variant 0.93 rifampicin
rpoC 765402 c.2035_2038delCTGG frameshift_variant 0.93 rifampicin
rpoC 765409 c.2041_2042insCAGT frameshift_variant 0.93 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.91 rifampicin
rpoC 765451 c.2082C>G synonymous_variant 0.9 rifampicin
rpoC 765452 p.Ala695Arg missense_variant 0.9 rifampicin
rpoC 765458 p.Ile697Val missense_variant 0.91 rifampicin Uncertain significance
rpoC 765466 c.2097C>T synonymous_variant 0.92 rifampicin
rpoC 765478 c.2109T>G synonymous_variant 0.92 rifampicin
rpoC 765496 c.2127C>G synonymous_variant 0.92 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765547 c.2178C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 0.79 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.79 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.79 rifampicin
rpoC 765590 p.Arg741Glu missense_variant 0.85 rifampicin
rpoC 765596 p.Lys743Gln missense_variant 0.77 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.87 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 0.93 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.94 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 0.94 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.98 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.99 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765947 c.2578T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 0.98 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 0.97 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.94 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.88 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.89 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.89 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.9 rifampicin
rpoC 766298 p.Thr977Leu missense_variant 0.92 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 0.92 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.92 rifampicin
rpoC 766324 c.2955C>G synonymous_variant 0.92 rifampicin
rpoC 766333 c.2964G>C synonymous_variant 0.93 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.95 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766411 c.3042C>G synonymous_variant 1.0 rifampicin
rpoC 766423 c.3054T>C synonymous_variant 1.0 rifampicin
rpoC 766428 c.3060_3061insACC conservative_inframe_insertion 1.0 rifampicin
rpoC 766432 c.3063T>C synonymous_variant 1.0 rifampicin
rpoC 766434 c.3065_3066delAGinsGCAGC missense_variant&conservative_inframe_insertion 1.0 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 1.0 rifampicin
rpoC 766494 p.Gly1042Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 766517 p.Thr1050Ser missense_variant 0.97 rifampicin
rpoC 766522 c.3153C>T synonymous_variant 0.96 rifampicin
rpoC 766528 c.3159T>G synonymous_variant 0.94 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.87 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 0.91 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.88 rifampicin
rpoC 766681 c.3312C>T synonymous_variant 0.9 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 0.92 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.93 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.94 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 0.95 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.94 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.95 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.98 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 0.98 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>G synonymous_variant 0.97 rifampicin
rpoC 766861 c.3492G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.97 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 0.97 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.97 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.97 rifampicin
rpoC 766907 c.3538C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766911 p.Ile1181Thr missense_variant 0.97 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 0.97 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766942 c.3573C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766951 c.3582G>T synonymous_variant 0.99 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>T synonymous_variant 1.0 rifampicin
rpoC 766981 c.3612T>C synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767038 c.3669G>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767155 c.3786C>G synonymous_variant 1.0 rifampicin
rpoC 767161 c.3792C>T synonymous_variant 1.0 rifampicin
rpoC 767162 p.Asn1265Pro missense_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
mmpL5 775796 c.2683_2685delTTTinsAG frameshift_variant&stop_gained 0.82 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775802 p.Met893Ile missense_variant 0.5 clofazimine
bedaquiline
mmpL5 775817 c.2664T>C synonymous_variant 0.87 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775826 c.2655G>C synonymous_variant 0.38 clofazimine
bedaquiline
mmpL5 775829 c.2652C>G synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 775832 c.2649C>G synonymous_variant 0.72 clofazimine
bedaquiline
mmpL5 775835 c.2646C>G synonymous_variant 0.74 clofazimine
bedaquiline
mmpL5 775847 c.2634G>C synonymous_variant 0.54 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 0.91 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775895 c.2584_2586delATCinsCG frameshift_variant&missense_variant 0.5 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775898 c.2583G>A synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 775904 c.2577G>A synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 775907 c.2572_2574delCTCinsTG frameshift_variant&synonymous_variant 0.61 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775910 c.2571G>C synonymous_variant 0.51 clofazimine
bedaquiline
mmpL5 775913 c.2566_2568delGCCinsTA frameshift_variant&missense_variant 0.6 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>G synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 775939 p.Ala848Ser missense_variant 0.47 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.65 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775955 p.Ile842Met missense_variant 0.31 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.41 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.89 clofazimine
bedaquiline
mmpL5 775975 p.Leu836Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 c.2488_2490delGAGinsAC frameshift_variant&missense_variant 0.62 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775997 c.2484T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2481G>C synonymous_variant 0.61 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.9 clofazimine
bedaquiline
mmpL5 776015 c.2464_2466delATCinsTG frameshift_variant&missense_variant 0.39 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776018 c.2461_2463delCTGinsTC frameshift_variant&synonymous_variant 0.56 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776021 c.2458_2460delGTGinsAC frameshift_variant&missense_variant 0.55 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776030 c.2451G>C synonymous_variant 0.96 clofazimine
bedaquiline
mmpL5 776039 c.2442C>T synonymous_variant 0.35 clofazimine
bedaquiline
mmpL5 776053 p.Leu810Val missense_variant 0.66 clofazimine
bedaquiline
mmpL5 776060 c.2421C>G synonymous_variant 0.91 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 776075 c.2406C>G synonymous_variant 0.69 clofazimine
bedaquiline
mmpL5 776078 c.2403C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 776081 c.2400G>C synonymous_variant 0.6 clofazimine
bedaquiline
mmpL5 776087 c.2394C>G synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 776093 c.2388C>A synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
rpsL 781592 c.33T>G synonymous_variant 0.86 streptomycin
rpsL 781595 c.36T>C synonymous_variant 0.93 streptomycin
rpsL 781598 c.39G>T synonymous_variant 0.86 streptomycin
rpsL 781605 p.Ile16Pro missense_variant 0.86 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 0.86 streptomycin Uncertain significance
rpsL 781616 c.57C>G synonymous_variant 0.86 streptomycin
rpsL 781617 p.Lys20Arg missense_variant 0.86 streptomycin
rpsL 781620 p.Thr21Val missense_variant 0.86 streptomycin
rpsL 781625 c.66G>C synonymous_variant 0.86 streptomycin
rpsL 781628 c.69T>A synonymous_variant 0.87 streptomycin
rpsL 781631 c.72G>C synonymous_variant 0.88 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.93 streptomycin
rpsL 781652 c.93T>C synonymous_variant 0.93 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.93 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.93 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.98 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.98 streptomycin
rpsL 781718 c.159C>A synonymous_variant 0.98 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781733 c.174G>C synonymous_variant 0.97 streptomycin
rpsL 781735 p.Ser59Thr missense_variant 0.97 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.98 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.98 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.96 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.96 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.97 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.98 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.98 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.97 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.98 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781865 c.306G>C synonymous_variant 0.98 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.98 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.98 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.98 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.98 streptomycin
rpsL 781904 c.345C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 0.93 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 0.94 linezolid
rplC 800537 c.-272C>G upstream_gene_variant 0.95 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.95 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.97 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.95 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 0.95 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 0.95 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 0.95 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.95 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.95 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.95 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 0.95 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.95 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.96 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.98 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.98 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.98 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.97 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.97 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.97 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.98 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.98 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.98 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.98 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.98 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.98 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.98 linezolid
rplC 800774 c.-35C>T upstream_gene_variant 0.98 linezolid
rplC 800799 c.-10_-8delGGAinsC upstream_gene_variant 0.94 linezolid
rplC 800807 c.-2C>A upstream_gene_variant 0.94 linezolid
rplC 800814 c.6A>T synonymous_variant 0.94 linezolid
rplC 800815 c.7_9delCGAinsAG frameshift_variant&synonymous_variant 0.94 linezolid
rplC 800829 c.21C>G synonymous_variant 0.95 linezolid
rplC 800832 c.24T>C synonymous_variant 0.96 linezolid
rplC 800844 c.36T>C synonymous_variant 0.96 linezolid
rplC 800856 c.48A>G synonymous_variant 0.98 linezolid
rplC 800865 c.57A>G synonymous_variant 0.98 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.98 linezolid
rplC 800874 c.66A>G synonymous_variant 0.98 linezolid
rplC 800877 c.69A>C synonymous_variant 0.98 linezolid
rplC 800880 c.72A>G synonymous_variant 0.98 linezolid
rplC 800889 c.81C>G synonymous_variant 0.98 linezolid
rplC 800892 c.84G>C synonymous_variant 0.98 linezolid
rplC 800904 c.96G>C synonymous_variant 1.0 linezolid
rplC 800913 c.105G>C synonymous_variant 0.98 linezolid
rplC 800916 c.108A>C synonymous_variant 0.98 linezolid
rplC 800919 c.111C>G synonymous_variant 0.98 linezolid
rplC 800931 c.123G>T synonymous_variant 0.98 linezolid
rplC 800937 c.129A>G synonymous_variant 0.97 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800981 p.Ser58Asn missense_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 800994 c.186C>G synonymous_variant 1.0 linezolid
rplC 801008 p.Thr67Lys missense_variant 1.0 linezolid
rplC 801019 p.Thr71Glu missense_variant 1.0 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801117 c.309G>C synonymous_variant 1.0 linezolid
rplC 801127 p.Ala107Thr missense_variant 1.0 linezolid
rplC 801132 c.324T>C synonymous_variant 1.0 linezolid
rplC 801156 c.348T>C synonymous_variant 1.0 linezolid
rplC 801160 c.352_353delTCinsAG synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 0.98 linezolid
rplC 801180 c.372C>G synonymous_variant 0.98 linezolid
rplC 801195 c.387G>C synonymous_variant 0.98 linezolid
rplC 801201 c.393C>T synonymous_variant 0.96 linezolid
rplC 801210 c.402T>C synonymous_variant 0.98 linezolid
rplC 801222 c.414T>C synonymous_variant 0.98 linezolid
rplC 801228 c.420T>C synonymous_variant 0.98 linezolid
rplC 801229 p.Ala141Thr missense_variant 0.98 linezolid
rplC 801252 c.444G>C synonymous_variant 0.98 linezolid
rplC 801255 c.447C>T synonymous_variant 0.98 linezolid
rplC 801267 c.459A>C synonymous_variant 0.98 linezolid
rplC 801270 c.462T>C synonymous_variant 0.98 linezolid
rplC 801273 c.465C>G synonymous_variant 0.98 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.98 linezolid
rplC 801303 c.495G>C synonymous_variant 0.98 linezolid
rplC 801309 c.501C>G synonymous_variant 0.95 linezolid
rplC 801312 c.504G>C synonymous_variant 0.94 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801330 c.522G>C synonymous_variant 0.95 linezolid
rplC 801331 c.523_525delGTGinsAC frameshift_variant&missense_variant 0.95 linezolid
rplC 801337 p.Val177Thr missense_variant 0.95 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.95 linezolid
rplC 801348 c.540T>G synonymous_variant 0.95 linezolid
rplC 801357 c.549T>C synonymous_variant 0.9 linezolid
rplC 801385 c.577C>T synonymous_variant 0.82 linezolid
fbiC 1303497 c.567G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303971 c.1041T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303977 c.1047C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303980 c.1050G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303995 c.1065C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303998 c.1068T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304001 c.1071C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304004 c.1074A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304008 c.1078T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304013 c.1083G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304019 c.1089C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304031 c.1101C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304040 c.1110C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304048 p.Ala373Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304106 c.1176G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304118 c.1188C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304127 c.1197A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304577 c.1647C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304607 c.1677C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304631 c.1701C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304652 c.1722C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304655 c.1725C>T synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304658 c.1728C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304709 c.1779C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304778 c.1848T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304826 c.1896G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.94 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304835 c.1905G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304856 c.1926C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304871 c.1941G>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304877 c.1947T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304887 c.1957C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304894 p.Gly655Ala missense_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304901 c.1971C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304910 c.1980G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304916 c.1986T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304922 c.1992C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304931 c.2001C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304940 c.2010A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304967 c.2037G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364667 c.255T>C synonymous_variant 0.91 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.92 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 0.95 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.95 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.96 pyrazinamide
sigE 1364718 c.306C>T synonymous_variant 0.96 pyrazinamide
sigE 1364727 c.315C>T synonymous_variant 0.96 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.97 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.96 pyrazinamide
sigE 1364767 c.355_357delAGGinsCC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
sigE 1364772 c.360G>C synonymous_variant 0.96 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 0.92 pyrazinamide
sigE 1364782 c.370_372delGTCinsCG frameshift_variant&missense_variant 0.92 pyrazinamide Uncertain significance
sigE 1364790 c.378T>C synonymous_variant 0.92 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.93 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 0.97 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.93 pyrazinamide
sigE 1364818 c.406_408delCTAinsTG frameshift_variant&stop_gained 0.93 pyrazinamide Uncertain significance
sigE 1364832 c.420C>G synonymous_variant 0.93 pyrazinamide
sigE 1364835 c.423C>G synonymous_variant 0.93 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.93 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.92 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.91 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 0.9 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 0.88 pyrazinamide
sigE 1364877 c.465G>A synonymous_variant 0.88 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.92 pyrazinamide
sigE 1364886 c.474G>A synonymous_variant 0.9 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.9 pyrazinamide Uncertain significance
sigE 1364892 c.480C>G synonymous_variant 0.92 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.95 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.95 pyrazinamide
sigE 1364920 p.Glu170Ser missense_variant 0.95 pyrazinamide
sigE 1364950 c.538_540delGCAinsTG frameshift_variant&stop_gained 1.0 pyrazinamide Uncertain significance
sigE 1364956 c.544C>T synonymous_variant 1.0 pyrazinamide
sigE 1364961 c.549A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364976 c.564T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.93 pyrazinamide
sigE 1364980 c.568_570delTTGinsCC frameshift_variant&missense_variant 0.93 pyrazinamide Uncertain significance
sigE 1364984 p.Ala191Asp missense_variant 0.93 pyrazinamide
sigE 1364994 c.582G>C synonymous_variant 0.93 pyrazinamide
sigE 1365000 c.588G>A synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
sigE 1365006 c.594T>C synonymous_variant 0.93 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.93 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.93 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.92 pyrazinamide
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472022 n.178_181delGGAC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472030 n.185delGinsCCTGCT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195delTinsGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472048 n.203T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_454delGT non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472303 n.458_470delGGTTCTCTCGGATinsTGAGG non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473289 n.1444T>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445_1446insAA non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473828 n.171G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474287 n.630delTinsCCC non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474293 n.637_644delCCTCTCCG non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474418 n.761C>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474421 n.764_767delGCGCinsA non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474437 n.780_781delGAinsTTGGT non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474710 n.1053delTinsACAA non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475202 n.1545G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475379 n.1722G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475382 n.1725A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475393 n.1737_1738insGATG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475397 n.1741_1745delCTCAC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475404 n.1747A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475606 n.1949T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475613 n.1956A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475615 n.1958C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475626 n.1969T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475627 n.1970G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475628 n.1971G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475629 n.1972G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475707 n.2050T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476058 n.2401T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476740 n.3083G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476741 n.3084G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476743 n.3086A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476744 n.3087G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476757 n.3100T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673667 c.-535A>G upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.73 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673682 c.-520G>C upstream_gene_variant 0.75 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673692 c.-510C>G upstream_gene_variant 0.77 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673697 c.-505G>C upstream_gene_variant 0.77 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.77 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.77 ethionamide
isoniazid
inhA 1673724 c.-478A>G upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673727 c.-475C>T upstream_gene_variant 0.77 ethionamide
isoniazid Uncertain significance
fabG1 1673733 p.Met98Ile missense_variant 0.77 ethionamide
isoniazid
inhA 1673736 c.-466G>A upstream_gene_variant 0.77 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.91 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.91 ethionamide
isoniazid
inhA 1673784 c.-418G>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673799 c.-403T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673805 c.-397G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673808 c.-394A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674474 c.273G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674502 c.301_303delACCinsTG frameshift_variant&missense_variant 0.87 ethionamide
isoniazid
inhA 1674507 c.306G>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674513 c.312C>G synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674534 c.333G>A synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.95 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.95 ethionamide
isoniazid
inhA 1674561 c.360C>T synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674576 c.375T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674579 c.378G>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.94 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 0.94 ethionamide
isoniazid
inhA 1674636 c.435C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674672 c.471C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674711 c.510G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674737 p.Ala179Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674741 c.540C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674742 p.Lys181Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674745 p.Tyr182His missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674750 c.549T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674786 c.585G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674804 c.603G>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid
inhA 1674810 c.609C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674813 c.612C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674825 c.624C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674828 c.627G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674839 p.Ala213Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674848 p.Gln216Arg missense_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674882 c.681G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674892 p.Asn231Asp missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674904 p.Ala235Pro missense_variant 0.96 ethionamide
isoniazid
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 0.83 pyrazinamide
rpsA 1833547 c.6G>A synonymous_variant 0.87 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 0.88 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>C synonymous_variant 0.97 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 0.97 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 0.97 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.97 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833691 c.150G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.97 pyrazinamide
rpsA 1833901 c.360G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834093 c.552G>C synonymous_variant 0.95 pyrazinamide
rpsA 1834094 c.553C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.94 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834234 c.693G>T synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.9 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834282 c.741C>T synonymous_variant 0.94 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.95 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834369 c.828C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834390 c.849G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834432 c.891G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834556 p.Ala339Gln missense_variant 0.98 pyrazinamide
rpsA 1834606 c.1065C>T synonymous_variant 0.95 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834627 c.1086C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834649 p.Thr370Leu missense_variant 0.96 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 0.96 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834720 c.1179C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.96 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.93 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 0.91 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.91 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.89 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.89 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.89 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.89 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.89 pyrazinamide
rpsA 1834811 c.1270C>A synonymous_variant 0.88 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.99 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.99 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.99 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.99 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.99 linezolid
tsnR 1853456 c.-150C>T upstream_gene_variant 0.98 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.98 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.98 linezolid
tsnR 1853474 c.-132C>G upstream_gene_variant 0.98 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.98 linezolid
tsnR 1853480 c.-126G>C upstream_gene_variant 0.96 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 0.96 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.93 linezolid
tsnR 1853498 c.-108G>C upstream_gene_variant 0.93 linezolid
tsnR 1853513 c.-93C>G upstream_gene_variant 0.92 linezolid
tsnR 1853516 c.-90C>G upstream_gene_variant 0.92 linezolid
tsnR 1853523 c.-83C>A upstream_gene_variant 0.94 linezolid
tsnR 1853527 c.-79C>G upstream_gene_variant 0.94 linezolid
tsnR 1853531 c.-75A>G upstream_gene_variant 0.94 linezolid
tsnR 1853539 c.-67_-66delAAinsCT upstream_gene_variant 0.92 linezolid
tsnR 1853552 c.-54C>G upstream_gene_variant 0.9 linezolid
ndh 2102233 c.810G>A synonymous_variant 0.7 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102242 c.801G>C synonymous_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102247 p.Val266Ile missense_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102259 p.Ser262Ala missense_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2102269 c.774C>G synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2102275 c.768C>G synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2102308 c.735G>C synonymous_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102317 p.Glu242Asp missense_variant 0.7 ethionamide
delamanid
isoniazid
ndh 2102320 c.723G>C synonymous_variant 0.64 ethionamide
delamanid
isoniazid
ndh 2102328 p.Leu239Met missense_variant 0.64 ethionamide
delamanid
isoniazid
ndh 2102334 p.Gln237Glu missense_variant 0.64 ethionamide
delamanid
isoniazid
kasA 2517917 c.-198G>T upstream_gene_variant 0.98 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518540 c.426T>G synonymous_variant 1.0 isoniazid
kasA 2518555 c.441C>G synonymous_variant 1.0 isoniazid
kasA 2518564 c.450C>G synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>G synonymous_variant 1.0 isoniazid
kasA 2518582 c.468G>T synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>G synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>A synonymous_variant 1.0 isoniazid
kasA 2518600 c.486C>A synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>C synonymous_variant 1.0 isoniazid
kasA 2518607 c.493_495delATGinsCC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Ile missense_variant 0.95 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.94 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.93 isoniazid
kasA 2518702 c.588C>A synonymous_variant 0.92 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.92 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.92 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.92 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.92 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.92 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.85 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.83 isoniazid
kasA 2519224 c.1110C>G synonymous_variant 1.0 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 1.0 isoniazid
kasA 2519233 c.1119C>T synonymous_variant 1.0 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 1.0 isoniazid
kasA 2519242 c.1128C>G synonymous_variant 1.0 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 1.0 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 1.0 isoniazid
kasA 2519260 c.1146T>C synonymous_variant 1.0 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 1.0 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
kasA 2519278 c.1164A>G synonymous_variant 1.0 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 1.0 isoniazid
kasA 2519284 c.1170C>A synonymous_variant 1.0 isoniazid
kasA 2519293 c.1179T>C synonymous_variant 1.0 isoniazid
kasA 2519298 p.Arg395Gln missense_variant 1.0 isoniazid
kasA 2519305 c.1191A>C synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
kasA 2519329 c.1215C>T synonymous_variant 1.0 isoniazid
kasA 2519332 c.1218C>A synonymous_variant 1.0 isoniazid
folC 2746702 c.897G>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2746705 c.894G>A synonymous_variant 0.82 para-aminosalicylic_acid
folC 2746708 c.891C>T synonymous_variant 0.82 para-aminosalicylic_acid
folC 2746728 c.871T>C synonymous_variant 0.82 para-aminosalicylic_acid
folC 2746738 c.861C>G synonymous_variant 0.9 para-aminosalicylic_acid
folC 2746744 c.855T>G synonymous_variant 0.9 para-aminosalicylic_acid
Rv2477c 2782549 c.1494T>C synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782567 c.1476C>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783025 c.1018C>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783038 c.1003_1005delGCCinsCG frameshift_variant&synonymous_variant 0.91 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783065 c.978C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.98 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.901_903delACCinsTA frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783155 c.888C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783193 p.Ser284Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783203 c.840C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783218 c.825C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783239 c.804G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783242 p.Thr267Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783245 c.796_798delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783254 c.789A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783488 c.555G>A synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783497 c.544_546delTTGinsCC frameshift_variant&missense_variant 0.79 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783502 c.541T>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783520 c.523T>C synonymous_variant 0.75 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 0.64 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783566 c.475_477delAACinsCT frameshift_variant&missense_variant 0.76 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783572 c.471A>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783575 c.468G>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783586 p.Ala153Pro missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783593 c.450T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783599 c.444G>T synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 0.86 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783629 c.414C>T synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783634 p.Leu137Ile missense_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783650 p.His131Ala missense_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783836 c.207C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783875 p.Lys56Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783926 c.117C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783947 c.96C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783953 c.90G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783957 p.Tyr29Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 p.Ser27Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783967 c.76T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783968 p.Thr25Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783986 c.57G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784017 p.Lys9Arg missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784024 p.Thr7Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784025 c.18C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784034 c.9G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2784037 c.6T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784047 c.-5G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2784051 c.-9C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996350 c.-389C>A upstream_gene_variant 1.0 capreomycin
Rv2680 2996360 p.Met86Leu missense_variant 1.0 capreomycin
Rv2680 2996366 c.262_264delTATinsCC frameshift_variant&missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2996374 c.-365G>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996377 p.Asp91Glu missense_variant 1.0 capreomycin
Rv2680 2996381 p.Ser93Ala missense_variant 1.0 capreomycin
Rv2680 2996386 c.282T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
Rv2681 2996389 c.-350A>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996401 c.-338T>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996404 p.Ile100Met missense_variant 1.0 capreomycin
Rv2681 2996407 c.-332C>G upstream_gene_variant 1.0 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 1.0 capreomycin
Rv2681 2996440 c.-299G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996443 c.-296T>C upstream_gene_variant 0.93 capreomycin
Rv2680 2996446 c.342A>G synonymous_variant 0.93 capreomycin Not assoc w R - Interim
Rv2681 2996449 c.-290C>G upstream_gene_variant 0.93 capreomycin
Rv2681 2996452 c.-287C>G upstream_gene_variant 0.93 capreomycin
Rv2681 2996458 c.-281C>G upstream_gene_variant 0.93 capreomycin
Rv2681 2996476 c.-263A>G upstream_gene_variant 0.93 capreomycin
Rv2681 2996491 c.-248G>C upstream_gene_variant 0.92 capreomycin
Rv2752c 3065547 c.645A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065553 c.639A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065559 c.633C>G synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065562 c.630T>G synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065576 p.Ala206Ser missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065592 c.600G>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065595 p.Leu199Phe missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065607 c.585C>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065612 p.Thr194Ala missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065613 c.579C>T synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065639 c.553C>T synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065640 c.552T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065643 c.549C>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065646 c.546C>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 p.Arg181Gln missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065653 p.Gly180Asp missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065659 p.Pro178Leu missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065666 c.526T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067309 p.Ile213Val missense_variant 0.8 para-aminosalicylic_acid
thyX 3067313 c.633G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067316 c.630A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067319 c.627G>C synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067322 c.624C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067354 p.Met198Val missense_variant 0.75 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067364 c.582C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067376 c.570G>C synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067382 c.564C>T synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067403 c.543C>A synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067412 c.534C>G synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067418 c.528C>G synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 0.81 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067640 c.306G>A synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067655 c.291G>C synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067665 p.Ile94Thr missense_variant 0.83 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067688 c.258G>C synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067763 c.181_183delCTCinsGG frameshift_variant&missense_variant 0.93 para-aminosalicylic_acid
thyX 3067770 p.Gly59Ala missense_variant 0.93 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 0.93 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067847 c.99C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 0.9 para-aminosalicylic_acid
thyX 3067856 p.Asp30Glu missense_variant 0.9 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.9 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.83 para-aminosalicylic_acid
thyX 3067894 c.52T>C synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 0.94 para-aminosalicylic_acid
thyX 3067901 c.45C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073818 c.654G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073821 c.651G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073824 c.648A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073884 c.588C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073888 p.Ser195Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074000 c.472C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074025 p.Phe149Leu missense_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074055 p.Glu139Ala missense_variant 1.0 para-aminosalicylic_acid
thyA 3074061 c.409_411delGAAinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3074070 c.402C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074094 c.378G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074106 c.366T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074112 p.Arg120Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074115 c.357G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074130 c.342G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074154 c.318T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074157 c.315C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074160 c.312A>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074163 c.307_309delGCTinsAC frameshift_variant&missense_variant 0.95 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074184 c.288A>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074193 c.277_279delATCinsGG frameshift_variant&missense_variant 0.95 para-aminosalicylic_acid
thyA 3074199 c.273G>A synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.95 para-aminosalicylic_acid
thyA 3074208 c.264C>T synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074214 p.Asp86Glu missense_variant 0.95 para-aminosalicylic_acid
lpqB 3624665 c.246C>T synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624671 p.Ala80Gly missense_variant 0.82 bedaquiline
rifampicin
lpqB 3624675 p.Asn79Arg missense_variant 0.91 bedaquiline
rifampicin
lpqB 3624677 c.234C>G synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624683 c.228G>C synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3624701 c.210T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624704 c.207G>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624707 c.204G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624713 c.198C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624725 c.186G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624728 c.183C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624734 c.177A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624755 c.156A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624761 c.150G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624776 c.133_135delGGTinsAC frameshift_variant&missense_variant 0.92 bedaquiline
rifampicin Uncertain significance
lpqB 3624783 p.Ser43Thr missense_variant 0.91 bedaquiline
rifampicin
lpqB 3624785 c.126G>C synonymous_variant 0.91 bedaquiline
rifampicin
lpqB 3625165 c.-255G>C upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625168 c.-258G>T upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625183 c.-273G>C upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625186 c.-276T>A upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625204 c.-294G>C upstream_gene_variant 0.75 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.87 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625243 c.-333T>G upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625246 c.-336G>C upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625258 c.-348G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
mtrB 3625262 p.Tyr451Phe missense_variant 0.89 bedaquiline
rifampicin
mtrB 3625264 c.1350C>T synonymous_variant 0.89 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625267 c.1347T>C synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 0.89 bedaquiline
rifampicin
lpqB 3625273 c.-363C>G upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625282 c.-372C>G upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.86 bedaquiline
rifampicin
mtrB 3625313 p.Arg434Lys missense_variant 0.84 bedaquiline
rifampicin
lpqB 3625315 c.-405G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625318 c.-408G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625321 c.1293A>G synonymous_variant 0.83 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625327 c.-417A>G upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3625342 c.1272C>G synonymous_variant 0.83 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625345 c.-435T>C upstream_gene_variant 0.81 bedaquiline
rifampicin
lpqB 3625528 c.-618G>T upstream_gene_variant 0.86 bedaquiline
rifampicin
lpqB 3625531 c.-621C>G upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625537 c.-627T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625540 c.-630G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625546 c.-636C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625570 c.-660G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625579 c.-669A>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625607 p.Thr336Ile missense_variant 0.98 bedaquiline
rifampicin Uncertain significance
lpqB 3625609 c.-699C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625612 c.-702G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625620 c.994C>T synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625623 p.Thr331Ser missense_variant 0.98 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625637 p.Ala326Asp missense_variant 0.98 bedaquiline
rifampicin
mtrB 3625650 p.Tyr322His missense_variant 0.98 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 0.98 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625678 c.-768C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625705 c.909C>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625755 p.Ala287Thr missense_variant 0.97 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625798 c.-888G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625837 c.777C>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 0.93 bedaquiline
rifampicin
lpqB 3625864 c.-954T>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3626062 c.552T>C synonymous_variant 0.73 bedaquiline
rifampicin
mtrB 3626065 c.549G>C synonymous_variant 0.73 bedaquiline
rifampicin
mtrB 3626077 c.537C>G synonymous_variant 0.73 bedaquiline
rifampicin
mtrB 3626080 c.534G>C synonymous_variant 0.73 bedaquiline
rifampicin
mtrB 3626092 p.Gly174Ala missense_variant 0.73 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626095 p.Glu173Asp missense_variant 0.73 bedaquiline
rifampicin
mtrB 3626101 c.511_513delCAGinsGC frameshift_variant&missense_variant 0.73 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626123 p.Ala164Ser missense_variant 0.8 bedaquiline
rifampicin
mtrB 3626126 p.Ala163Val missense_variant 0.8 bedaquiline
rifampicin
mtrB 3626131 c.483G>T synonymous_variant 0.8 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 0.89 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626744 c.-131G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 0.93 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626756 c.-143C>T upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3626776 c.-163A>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626780 c.-167T>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626786 c.-173A>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626822 c.-209T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrA 3626825 c.525T>A synonymous_variant 0.86 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626840 c.-227C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626858 c.-245A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626891 c.-278G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626906 c.442_444delAACinsCG frameshift_variant&missense_variant 0.93 bedaquiline
rifampicin
mtrA 3626909 c.441C>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626924 c.-311G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626927 c.-314G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3626933 c.-320C>T upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3626939 p.Glu137Asp missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626949 p.Ala134Gly missense_variant 0.96 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3626978 p.Asp124Glu missense_variant 0.98 bedaquiline
rifampicin Uncertain significance
mtrB 3626999 c.-386G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627011 c.-398T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3627014 c.-401G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrA 3627020 c.330G>A synonymous_variant 0.96 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin
mtrB 3627059 c.-446G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627092 c.-479C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627104 c.-491C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627125 c.-512C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627131 c.-518C>G upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627143 c.-530G>T upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627173 c.-560G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627185 c.163_165delTTGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrA 3627188 c.162A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627206 c.-593G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627215 c.-602G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627224 c.-611G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627233 c.-620T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627263 c.-650C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627269 c.81G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3627272 c.-659G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627296 c.-683T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627305 c.43_45delGCTinsCG frameshift_variant&synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3627308 c.-695C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627320 c.-707C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627325 c.-712T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877613 p.Ile299Val missense_variant 0.97 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877656 c.852T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 1.0 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>C synonymous_variant 0.98 rifampicin
rpoA 3877728 c.780C>G synonymous_variant 0.98 rifampicin
rpoA 3877740 c.768G>C synonymous_variant 0.98 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877794 c.714G>T synonymous_variant 0.98 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877896 c.612G>C synonymous_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.98 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877971 p.Asp179Glu missense_variant 0.96 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 0.95 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878001 c.505_507delTCAinsAGC synonymous_variant 0.93 rifampicin
rpoA 3878019 c.489A>G synonymous_variant 0.92 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 0.91 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.91 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.91 rifampicin
rpoA 3878034 c.474A>G synonymous_variant 0.91 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>C synonymous_variant 0.91 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 0.91 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.91 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.92 rifampicin
rpoA 3878064 c.444G>C synonymous_variant 0.92 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.93 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.94 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.96 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.96 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.96 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 0.96 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.96 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 0.96 rifampicin Uncertain significance
rpoA 3878160 c.348C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878172 c.336G>C synonymous_variant 0.94 rifampicin
rpoA 3878187 c.321C>G synonymous_variant 0.95 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878247 c.261G>C synonymous_variant 0.96 rifampicin
rpoA 3878253 c.255G>C synonymous_variant 0.96 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.96 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.96 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoA 3878274 c.234G>C synonymous_variant 0.95 rifampicin
rpoA 3878283 p.Glu75Asp missense_variant 0.97 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878358 c.150C>A synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.91 rifampicin
rpoA 3878843 c.-337_-336delCGinsAA upstream_gene_variant 1.0 rifampicin
rpoA 3878845 c.-338G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878886 c.-379G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878889 c.-382A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878890 c.-383C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878893 c.-388_-386delCACinsAG upstream_gene_variant 1.0 rifampicin
rpoA 3878896 c.-389G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878908 c.-403_-401delAACinsCTG upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878917 c.-410G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878938 c.-431T>C upstream_gene_variant 0.93 rifampicin
rpoA 3878942 c.-436_-435delATinsCA upstream_gene_variant 0.93 rifampicin
rpoA 3878944 c.-437G>T upstream_gene_variant 0.93 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.93 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.92 rifampicin Uncertain significance
ddn 3986615 c.-229C>T upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986636 c.-208C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986645 c.-199G>A upstream_gene_variant 0.97 delamanid
pretomanid
ddn 3986661 c.-183C>A upstream_gene_variant 0.96 delamanid
pretomanid
ddn 3986667 c.-177_-175delCTCinsACG upstream_gene_variant 0.96 delamanid
pretomanid
ddn 3986687 c.-157C>T upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986690 c.-154C>G upstream_gene_variant 0.94 delamanid
pretomanid
ddn 3986696 c.-148G>C upstream_gene_variant 0.88 delamanid
pretomanid
ddn 3986699 c.-145C>G upstream_gene_variant 0.88 delamanid
pretomanid
ddn 3986714 c.-130C>G upstream_gene_variant 0.86 delamanid
pretomanid
clpC1 4038335 c.2370C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038383 c.2322G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038392 c.2313C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038407 c.2298G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038416 c.2289C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038428 c.2277G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038435 p.Ala757Gln missense_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.97 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038449 c.2256C>G synonymous_variant 0.94 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.95 pyrazinamide
clpC1 4038461 c.2244G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038485 p.Gly740Glu missense_variant 0.95 pyrazinamide
clpC1 4038497 c.2206_2208delAGCinsGA frameshift_variant&missense_variant 0.95 pyrazinamide
clpC1 4038521 c.2182_2184delATCinsGG frameshift_variant&missense_variant 0.95 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.95 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 0.95 pyrazinamide
clpC1 4038587 c.2118C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038605 c.2100G>A synonymous_variant 0.98 pyrazinamide
clpC1 4038613 p.Asn698His missense_variant 0.98 pyrazinamide
clpC1 4038614 c.2091C>T synonymous_variant 0.98 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.96 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.96 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.96 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.96 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4038692 p.Ser671Lys missense_variant 0.97 pyrazinamide
clpC1 4038701 c.2004G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.95 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038752 c.1953G>A synonymous_variant 0.98 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4038815 c.1890G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>G synonymous_variant 0.99 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.99 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.99 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.97 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038974 c.1731T>G synonymous_variant 0.96 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 0.97 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.97 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.97 pyrazinamide
clpC1 4039031 c.1674T>G synonymous_variant 0.97 pyrazinamide
clpC1 4039037 c.1668T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039046 c.1659C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039070 c.1635G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039082 c.1623C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 0.93 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.9 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039190 c.1515C>A synonymous_variant 0.9 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.89 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039235 c.1470C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039241 c.1464G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039244 c.1461G>C synonymous_variant 0.9 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039292 c.1413C>T synonymous_variant 0.93 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.93 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039328 c.1377A>T synonymous_variant 0.94 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.91 pyrazinamide
clpC1 4039347 p.Arg453Gln missense_variant 0.91 pyrazinamide Uncertain significance
clpC1 4039349 c.1356C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039352 c.1353C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039360 p.Ser449Arg missense_variant 0.89 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.94 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039406 c.1299G>T synonymous_variant 0.91 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039412 c.1293T>C synonymous_variant 0.91 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.91 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039439 c.1266C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039445 c.1260C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039448 c.1257A>T synonymous_variant 0.85 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.83 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.83 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 0.91 pyrazinamide
clpC1 4039553 c.1152C>A synonymous_variant 0.88 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039570 p.Met379Val missense_variant 0.92 pyrazinamide
clpC1 4039571 c.1134G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 0.88 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039589 c.1116G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039601 c.1104G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039607 c.1098C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039610 c.1095G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039622 c.1083C>A synonymous_variant 0.98 pyrazinamide
clpC1 4039646 c.1059G>A synonymous_variant 0.95 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.97 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039691 c.1014G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039748 c.957G>A synonymous_variant 0.95 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.94 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.97 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039805 c.900C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039808 c.897G>A synonymous_variant 0.92 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.93 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 0.93 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.94 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.96 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039925 c.780C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.95 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 0.95 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.96 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039955 c.750G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 0.98 pyrazinamide
clpC1 4040015 c.690G>A synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040018 c.687G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040021 c.684A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040024 c.681A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040039 c.666G>A synonymous_variant 0.95 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.94 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.95 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.91 pyrazinamide
clpC1 4040180 c.525C>T synonymous_variant 0.93 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 0.94 pyrazinamide
clpC1 4040210 c.495G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040213 c.492T>A synonymous_variant 0.94 pyrazinamide
clpC1 4040225 c.480A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040228 c.477G>A synonymous_variant 0.96 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040243 c.462C>T synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040249 c.456A>G synonymous_variant 0.94 pyrazinamide
clpC1 4040257 p.Ala150Thr missense_variant 0.93 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>A synonymous_variant 0.89 pyrazinamide
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.88 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040335 c.370C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.98 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.97 pyrazinamide
clpC1 4040369 c.334_336delCTCinsTG frameshift_variant&synonymous_variant 0.97 pyrazinamide
clpC1 4040372 c.333C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040381 c.324T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.97 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.92 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.88 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040552 c.153G>A synonymous_variant 0.87 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040570 c.135C>G synonymous_variant 0.88 pyrazinamide
clpC1 4040573 c.132T>G synonymous_variant 0.88 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.81 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.8 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.8 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.86 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.86 pyrazinamide
clpC1 4040597 c.108C>A synonymous_variant 0.86 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.86 pyrazinamide
clpC1 4040603 c.102T>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040606 c.99T>C synonymous_variant 0.86 pyrazinamide
glpK 4138451 c.1305T>C synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138457 c.1299C>T synonymous_variant 0.93 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138464 p.Gly431Ala missense_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138487 c.1267_1269delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138495 p.Gln421Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138498 p.Leu420Met missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138500 p.Arg419His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138505 c.1251T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138514 c.1242A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138523 c.1233C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138532 c.1224G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138541 c.1215C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138661 c.1095T>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138664 c.1092G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138696 p.Pro354Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138702 p.Gln352Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138706 c.1050C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138721 p.Gln345His missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138731 p.Gly342Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138734 p.Ser341Pro missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138745 c.1011G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139312 c.444T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139321 c.435T>G synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139324 c.432A>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139327 c.429G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139336 c.420C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139356 p.Leu134Val missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139359 p.Asn133Asp missense_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139360 c.396A>T synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139363 c.393T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139366 c.390T>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139372 c.384A>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139375 p.Asp127Glu missense_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139380 c.376C>T synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139381 c.375G>C synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139387 c.369G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139399 c.357C>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139408 c.348T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139417 c.339A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139420 c.336T>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139588 c.168G>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Lys missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139603 c.153C>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139630 c.126C>T synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139637 p.Ala40Gly missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139639 c.115_117delGTGinsAC frameshift_variant&missense_variant 0.9 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139646 c.109_110insGCG conservative_inframe_insertion 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139654 c.99_101delTCA disruptive_inframe_deletion 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139699 c.57C>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240717 c.855T>C synonymous_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240736 p.Ser292Ala missense_variant 1.0 ethambutol
embC 4240766 c.904C>A synonymous_variant 1.0 ethambutol
embC 4240774 c.912C>G synonymous_variant 1.0 ethambutol
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240807 c.945C>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embC 4240819 c.957A>C synonymous_variant 0.97 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.97 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.97 ethambutol
embC 4240859 c.997C>T synonymous_variant 0.94 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.94 ethambutol
embC 4241104 c.1242G>A synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embC 4241107 c.1245G>C synonymous_variant 0.9 ethambutol
embC 4241109 p.Ala416Gly missense_variant 0.9 ethambutol
embC 4241123 c.1261C>A synonymous_variant 0.9 ethambutol
embC 4241167 c.1305C>G synonymous_variant 0.88 ethambutol
embC 4241179 c.1317G>C synonymous_variant 0.83 ethambutol
embC 4241195 p.Ser445Ala missense_variant 0.89 ethambutol
embC 4241198 p.Ile446Val missense_variant 0.94 ethambutol
embC 4241218 c.1356G>C synonymous_variant 0.92 ethambutol
embC 4241219 p.Ile453Val missense_variant 0.91 ethambutol
embB 4247401 c.888T>C synonymous_variant 0.85 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.89 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.9 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.9 ethambutol
embB 4247464 c.951C>G synonymous_variant 0.95 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.95 ethambutol
embB 4247491 c.978G>C synonymous_variant 0.94 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.94 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.94 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.89 ethambutol
embB 4247528 p.Leu339Met missense_variant 0.77 ethambutol
embB 4247537 p.His342Ser missense_variant 0.73 ethambutol
embB 4248118 c.1605T>G synonymous_variant 1.0 ethambutol
embB 4248133 c.1620C>G synonymous_variant 1.0 ethambutol
embB 4248139 c.1626C>G synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248159 p.Cys549Ser missense_variant 1.0 ethambutol
embB 4248167 p.Thr552Val missense_variant 1.0 ethambutol
embB 4248170 p.Ala553Ser missense_variant 1.0 ethambutol
embB 4248173 p.Val554Met missense_variant 1.0 ethambutol
embB 4248185 p.Leu558Met missense_variant 1.0 ethambutol
embB 4248190 c.1677G>C synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248206 c.1693_1695delAGCinsGT frameshift_variant&missense_variant 1.0 ethambutol
embB 4248214 c.1701C>G synonymous_variant 1.0 ethambutol
embB 4248217 c.1704C>G synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>C synonymous_variant 1.0 ethambutol
embB 4248226 c.1713G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248256 c.1743C>G synonymous_variant 1.0 ethambutol
embB 4248259 p.Met582Ile missense_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248280 c.1767C>G synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 1.0 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>C synonymous_variant 1.0 ethambutol
embB 4248328 c.1815G>C synonymous_variant 1.0 ethambutol
embB 4248334 c.1821C>G synonymous_variant 1.0 ethambutol
aftB 4269164 c.-328T>C upstream_gene_variant 1.0 ethambutol
aftB 4269171 c.-335C>G upstream_gene_variant 1.0 ethambutol