Run ID: ERR4769521
Sample name:
Date: 2024-04-16T09:49:55.071572
Number of reads: 601911
Percentage reads mapped: 15.86
Median coverage: 3.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: RR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4 | Euro-American | None | 0.94 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.94 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | ||||
ethambutol | embB | p.Asp311Gly | Mutation from literature | |
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.166_168delTCCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
c.202_204delCTGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.205_207delCTGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.730_732delAACinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiC | c.1132_1134delGCGinsTC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.1135_1137delGCGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1189_1191delAAAinsCG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 490948 | c.166_168delTCCinsGG | frameshift_variant&missense_variant | 0.94 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 490984 | c.202_204delCTGinsAC | frameshift_variant&missense_variant | 0.98 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 490987 | c.205_207delCTGinsGC | frameshift_variant&missense_variant | 0.98 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 0.97 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491512 | c.730_732delAACinsGG | frameshift_variant&missense_variant | 0.79 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
fbiC | 1304062 | c.1132_1134delGCGinsTC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304065 | c.1135_1137delGCGinsAC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304119 | c.1189_1191delAAAinsCG | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
embB | 4247445 | p.Asp311Gly | missense_variant | 0.9 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 660 | c.660G>C | synonymous_variant | 0.95 | isoniazid | Not assoc w R - Interim |
dnaA | 663 | c.663A>G | synonymous_variant | 0.9 | isoniazid | Not assoc w R - Interim |
dnaA | 672 | c.672T>C | synonymous_variant | 0.92 | isoniazid | Not assoc w R - Interim |
dnaA | 678 | c.678A>G | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
dnaA | 690 | c.690G>C | synonymous_variant | 0.91 | isoniazid | |
dnaA | 693 | c.693A>G | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
dnaA | 705 | c.705A>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.94 | isoniazid | |
dnaA | 714 | c.714C>G | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
dnaA | 741 | c.741T>C | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
dnaA | 744 | c.744C>T | synonymous_variant | 0.93 | isoniazid | |
dnaA | 747 | c.747G>C | synonymous_variant | 0.94 | isoniazid | |
dnaA | 750 | c.750C>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.93 | isoniazid | |
dnaA | 767 | p.Val256Ala | missense_variant | 0.92 | isoniazid | |
dnaA | 769 | c.769_771delGCAinsTC | frameshift_variant&missense_variant | 0.91 | isoniazid | Uncertain significance |
dnaA | 777 | c.777A>G | synonymous_variant | 0.93 | isoniazid | |
dnaA | 793 | c.793_795delGTAinsAC | frameshift_variant&missense_variant | 0.91 | isoniazid | Uncertain significance |
dnaA | 805 | c.805T>C | synonymous_variant | 0.93 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.92 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.91 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.91 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.91 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.91 | isoniazid | |
dnaA | 843 | c.843T>C | synonymous_variant | 0.91 | isoniazid | Not assoc w R - Interim |
dnaA | 846 | c.846T>C | synonymous_variant | 0.89 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.91 | isoniazid | |
dnaA | 852 | c.852G>A | synonymous_variant | 0.91 | isoniazid | Not assoc w R - Interim |
dnaA | 877 | c.877T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.98 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 921 | c.921A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 933 | c.933C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 955 | c.955_957delAGAinsCG | frameshift_variant&synonymous_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 963 | c.963C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 975 | c.975G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 976 | c.976C>T | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 984 | c.984T>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 993 | c.993A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 996 | c.996A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1002 | c.1002G>A | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1014 | c.1014C>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1020 | c.1020C>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1035 | c.1035A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1038 | c.1038A>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 1047 | p.Glu349Asp | missense_variant | 0.9 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.9 | isoniazid | |
dnaA | 1071 | c.1071C>G | synonymous_variant | 0.9 | isoniazid | |
dnaA | 1077 | c.1077A>G | synonymous_variant | 0.9 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.92 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1113 | c.1113A>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1128 | c.1128G>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1173 | c.1174_1177delAAAG | frameshift_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 1179 | c.1179_1180insGTCA | frameshift_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1194 | c.1194G>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1203 | c.1203T>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1210 | p.Ala404Ser | missense_variant | 0.98 | isoniazid | |
dnaA | 1215 | c.1215C>T | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.95 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1243 | p.Thr415Ala | missense_variant | 0.95 | isoniazid | Uncertain significance |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.93 | isoniazid | |
dnaA | 1266 | c.1266A>G | synonymous_variant | 0.91 | isoniazid | |
gyrB | 6178 | c.939C>T | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6203 | p.Ser322Ala | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6208 | c.969G>A | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6214 | c.975G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6215 | c.976_978delTCGinsAGC | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6238 | c.999G>A | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6310 | c.-992G>C | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6325 | c.-977C>G | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6326 | p.Ser363Ala | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6346 | c.1107C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6362 | c.1123_1125delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6397 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6398 | p.Val387Ile | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6416 | p.Thr393Gly | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6427 | c.-875T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6430 | c.-872A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6440 | p.Thr401Ala | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6445 | p.Asp402Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrB | 6452 | p.Val405Thr | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6469 | c.-833T>G | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6472 | c.-830G>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6475 | c.-827C>G | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6478 | c.-824G>C | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6484 | c.-818A>G | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6487 | c.1248C>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6490 | c.-812T>C | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6496 | c.-806G>C | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6499 | c.-803A>G | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6508 | c.-794A>G | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6511 | c.-791A>T | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6523 | c.-779G>T | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6547 | c.-755T>C | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6550 | c.-752A>C | upstream_gene_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6551 | c.1312T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6571 | c.-731T>C | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6577 | c.1338T>C | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6583 | c.-719G>C | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6604 | c.-698G>C | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6608 | p.Val457Ile | missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6613 | c.-689A>G | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6619 | c.-683T>C | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6622 | c.-680C>T | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6628 | c.-674C>G | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6640 | c.-662A>C | upstream_gene_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6643 | c.-659A>G | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>G | upstream_gene_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6680 | c.1441C>T | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6733 | c.-569G>A | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6763 | c.-539G>A | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6775 | c.-527G>T | upstream_gene_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Ser | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6811 | c.1572C>T | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6824 | c.1585C>T | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6860 | p.Ser541Ala | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6869 | c.-433T>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6872 | c.-430T>C | upstream_gene_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6896 | p.Arg553Lys | missense_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6922 | c.1683G>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6924 | p.Phe562Tyr | missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6926 | c.1687T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6931 | c.1692A>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6940 | c.-362G>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6955 | c.-347G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6961 | c.-341G>A | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6970 | p.Asp577Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6988 | c.-314C>G | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7000 | c.-302C>T | upstream_gene_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7005 | p.Gly589Ala | missense_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7015 | c.-287G>A | upstream_gene_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7021 | c.-281G>C | upstream_gene_variant | 0.92 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7487 | c.186C>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7490 | c.189C>T | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7496 | c.195C>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7499 | c.198G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7511 | c.210C>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7514 | c.213C>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7517 | c.216G>A | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7526 | c.225G>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7529 | c.228G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7532 | c.231T>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7568 | c.267C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7592 | c.291G>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7626 | c.325C>T | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7679 | c.378G>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7700 | c.399G>A | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7710 | c.409T>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7748 | c.447A>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7758 | p.Ile153Val | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7769 | c.468C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7802 | c.501C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7814 | c.513C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7821 | c.520C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7832 | c.531G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7841 | c.540C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7886 | c.585T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7898 | p.Asp199Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8121 | c.820T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8187 | c.886_888delCTGinsAC | frameshift_variant&missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8199 | p.Ser300Ala | missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8210 | c.909G>A | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>G | synonymous_variant | 0.99 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8235 | c.934_936delTTAinsCG | frameshift_variant&missense_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8258 | c.957G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8357 | c.1056G>C | synonymous_variant | 0.99 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8382 | p.Leu361Met | missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8390 | c.1089C>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8402 | c.1101C>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8405 | c.1104C>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8408 | c.1107A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8417 | c.1116C>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8459 | c.1158G>A | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8489 | c.1188A>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8501 | c.1200G>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8513 | c.1212C>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8520 | c.1219C>T | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8543 | c.1242C>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8552 | c.1251_1254delCCGGinsGC | frameshift_variant&synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8559 | c.1258_1260delGGAinsAGGGC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8588 | p.Glu429Asp | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8645 | c.1344C>G | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8651 | c.1350C>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8751 | p.Ala484Lys | missense_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.98 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8783 | c.1482G>T | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8792 | c.1491G>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8796 | c.1495_1497delATCinsGG | frameshift_variant&missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8813 | p.Asp504Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8900 | c.1599G>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.94 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8967 | p.Ala556Asn | missense_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8981 | c.1680G>C | synonymous_variant | 0.93 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.95 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.95 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9017 | c.1716C>G | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9206 | c.1905C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9207 | p.Lys636Arg | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9227 | c.1926C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9236 | c.1935G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9263 | c.1962C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9267 | p.Asn656Gly | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9287 | c.1986G>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9311 | c.2010C>T | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9356 | c.2055G>A | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>G | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9398 | c.2097T>C | synonymous_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9419 | c.2118T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9420 | p.Ile707Ala | missense_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9455 | c.2154T>C | synonymous_variant | 0.98 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9464 | c.2163C>A | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9476 | c.2175G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9479 | c.2178G>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9485 | c.2184A>C | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9488 | c.2187G>T | synonymous_variant | 0.97 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9494 | c.2193T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9497 | c.2196G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9500 | c.2199A>G | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9503 | c.2202T>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9509 | c.2208G>C | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9518 | c.2217A>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9527 | c.2226A>G | synonymous_variant | 0.96 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9542 | c.2241T>C | synonymous_variant | 0.93 | levofloxacin | |
moxifloxacin | ||||||
fgd1 | 490851 | c.69A>G | synonymous_variant | 0.86 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490853 | p.Ala24Gly | missense_variant | 0.86 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490859 | p.Ala26Glu | missense_variant | 0.81 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490869 | c.87C>G | synonymous_variant | 0.84 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490890 | c.108C>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490899 | c.117C>T | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490902 | c.120T>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>T | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490935 | c.153C>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490962 | c.180T>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490968 | c.186C>T | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490971 | c.189A>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490980 | p.Asn66Lys | missense_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491010 | c.228C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491016 | c.234C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491037 | c.255C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491064 | c.282A>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491073 | c.291C>T | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491077 | p.Asn99Asp | missense_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491082 | c.300T>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491106 | c.324T>A | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491115 | c.333G>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491133 | c.351A>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Asp | missense_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491187 | c.405G>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491461 | p.Lys227Arg | missense_variant | 0.82 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491472 | c.690A>G | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491487 | c.705C>T | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491496 | c.714C>T | synonymous_variant | 0.88 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491499 | c.717G>C | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491502 | p.Glu240Asp | missense_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491508 | c.726A>G | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491509 | c.727T>C | synonymous_variant | 0.83 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491521 | c.739C>A | synonymous_variant | 0.84 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.85 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>G | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491620 | p.Ile280Val | missense_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491646 | c.864G>A | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491649 | c.867C>T | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491655 | c.873C>T | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491658 | c.876A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491673 | c.891A>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491676 | c.894T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491679 | c.897A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491687 | p.Thr302Lys | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491697 | c.915G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 575652 | p.Arg102Pro | missense_variant | 0.82 | ethionamide | |
isoniazid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.87 | ethionamide | |
isoniazid | ||||||
mshA | 575665 | c.318G>A | synonymous_variant | 0.89 | ethionamide | |
isoniazid | ||||||
mshA | 575671 | c.324G>C | synonymous_variant | 0.91 | ethionamide | |
isoniazid | ||||||
mshA | 575683 | c.336G>C | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575689 | c.342G>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.94 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575744 | p.Ala133Thr | missense_variant | 0.96 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575749 | c.402C>G | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575752 | c.405G>C | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575770 | c.423G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Thr | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575842 | c.495G>A | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575845 | c.498C>G | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575878 | c.531A>G | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575896 | c.549G>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575905 | c.558G>C | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575908 | c.561A>G | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575911 | c.564G>T | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575917 | p.Asp190Glu | missense_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575920 | c.573C>T | synonymous_variant | 0.92 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575925 | p.Gly193Ala | missense_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575929 | c.582C>G | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575932 | c.585G>A | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575944 | c.597T>C | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575945 | p.Thr200Ala | missense_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575953 | c.606G>C | synonymous_variant | 0.91 | ethionamide | |
isoniazid | ||||||
mshA | 575956 | c.609G>A | synonymous_variant | 0.91 | ethionamide | |
isoniazid | ||||||
ccsA | 619615 | c.-276C>G | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619629 | c.-262G>C | upstream_gene_variant | 0.85 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619648 | c.-243C>G | upstream_gene_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619654 | c.-237A>G | upstream_gene_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619657 | c.-234C>G | upstream_gene_variant | 0.89 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619669 | c.-222G>T | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>G | upstream_gene_variant | 0.87 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619696 | c.-195C>G | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619697 | c.-194_-192delAGGinsCA | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619702 | c.-189C>A | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619706 | c.-185_-183delGTGinsAC | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619713 | c.-178C>T | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619723 | c.-168G>C | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619727 | c.-164delAinsGC | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619732 | c.-158delG | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619746 | c.-145A>G | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619762 | c.-129C>G | upstream_gene_variant | 0.87 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619763 | c.-128C>T | upstream_gene_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619766 | c.-125_-123delACGinsGC | upstream_gene_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619774 | c.-117C>G | upstream_gene_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619783 | c.-108C>G | upstream_gene_variant | 0.82 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619794 | c.-97C>A | upstream_gene_variant | 0.8 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620238 | c.348G>C | synonymous_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620247 | p.Leu119Phe | missense_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620249 | p.Ser120Cys | missense_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620253 | c.363G>C | synonymous_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620256 | c.366C>G | synonymous_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620257 | p.Ile123Val | missense_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620264 | p.Gly125Ala | missense_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620268 | c.378G>C | synonymous_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620271 | c.381C>G | synonymous_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>C | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620296 | p.Pro136Ala | missense_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620311 | p.Leu141Val | missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620316 | c.426G>C | synonymous_variant | 0.96 | capreomycin | |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620337 | c.447C>G | synonymous_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>C | synonymous_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620409 | c.519C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620439 | c.549T>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620442 | c.552G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620631 | c.741T>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620634 | c.744C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620670 | c.780C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620709 | c.819G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620710 | c.820_822delGTGinsAC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620736 | c.846G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620754 | c.864G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620758 | p.Arg290Lys | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620784 | c.894C>A | synonymous_variant | 0.94 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620793 | c.903G>C | synonymous_variant | 0.93 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620796 | c.906C>G | synonymous_variant | 0.92 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620802 | c.912C>G | synonymous_variant | 0.91 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 657596 | c.-126G>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657620 | c.-150C>T | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657635 | c.-167_-165delAGCinsTCG | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657640 | c.-170A>T | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657641 | c.-171C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657647 | c.-177C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657670 | c.-200A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.98 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
nusG | 734421 | c.168A>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734424 | c.171G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734499 | c.246G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734505 | c.252G>C | synonymous_variant | 0.97 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.96 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
nusG | 734814 | c.561G>C | synonymous_variant | 0.8 | rifampicin | |
nusG | 734820 | c.567A>G | synonymous_variant | 0.8 | rifampicin | Not assoc w R - Interim |
nusG | 734826 | c.573A>C | synonymous_variant | 0.8 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.9 | rifampicin | |
nusG | 734853 | c.600A>G | synonymous_variant | 0.9 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 0.9 | rifampicin | |
nusG | 734862 | c.609C>G | synonymous_variant | 0.9 | rifampicin | |
nusG | 734863 | p.Thr204Ser | missense_variant | 0.9 | rifampicin | |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 760140 | p.Pro112Ser | missense_variant | 0.92 | rifampicin | |
rpoB | 760148 | c.342C>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 760208 | p.Ile134Met | missense_variant | 0.9 | rifampicin | |
rpoB | 760212 | p.Asn136Ala | missense_variant | 0.9 | rifampicin | |
rpoB | 760215 | c.409_411delAACinsGG | frameshift_variant&missense_variant | 0.9 | rifampicin | |
rpoB | 760219 | p.Thr138Ser | missense_variant | 0.9 | rifampicin | |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.91 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 760244 | c.438G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760310 | c.504G>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760316 | c.510C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760317 | c.511_513delAGCinsTCG | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760328 | c.522G>T | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760407 | p.Ser201Gly | missense_variant | 0.96 | rifampicin | Uncertain significance |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 760454 | c.648C>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760478 | c.672C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760487 | c.681G>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760502 | c.696C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.98 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.97 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760551 | c.745_746delTCinsAG | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760563 | c.757delCinsAT | frameshift_variant&synonymous_variant | 1.0 | rifampicin | |
rpoB | 760566 | p.Ser254Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760567 | c.762delG | frameshift_variant | 1.0 | rifampicin | |
rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760608 | c.802C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760916 | c.1110C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760958 | c.1152G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 760965 | p.Met387Leu | missense_variant | 0.92 | rifampicin | Uncertain significance |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 760973 | c.1167G>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 760988 | c.1182C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 760997 | c.1191G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761087 | c.1281C>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761088 | c.1282_1284delAGCinsTCG | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761147 | c.1341C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761174 | c.1368T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761195 | c.1389G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761198 | c.1392G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761204 | c.1398C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761217 | c.1411_1413delCCGinsGC | frameshift_variant&missense_variant | 0.94 | rifampicin | |
rpoB | 761220 | c.1414_1416delTCGinsAGC | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761264 | c.1458C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 761300 | c.1494G>C | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 761303 | c.1497G>A | synonymous_variant | 0.89 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.89 | rifampicin | Not assoc w R - Interim |
rpoB | 761345 | c.1539G>C | synonymous_variant | 0.88 | rifampicin | |
rpoB | 761357 | c.1551G>A | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.95 | rifampicin | |
rpoB | 761366 | c.1560C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761375 | c.1569G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761403 | p.His533Tyr | missense_variant | 1.0 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 761555 | c.1749G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761558 | c.1752C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 761561 | c.1755C>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761600 | c.1794T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761612 | c.1806G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761627 | c.1821C>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761666 | c.1860G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761669 | c.1863C>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761682 | c.1876C>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761687 | c.1881C>T | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.94 | rifampicin | |
rpoB | 761705 | c.1899C>T | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761723 | p.Glu639Asp | missense_variant | 0.9 | rifampicin | Not assoc w R |
rpoB | 761724 | c.1918_1920delGAAinsAC | frameshift_variant&missense_variant | 0.89 | rifampicin | |
rpoB | 761727 | p.Ser641Ala | missense_variant | 0.89 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.9 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.91 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.91 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.97 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.97 | rifampicin | |
rpoB | 761791 | p.Arg662Gln | missense_variant | 0.95 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.95 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.91 | rifampicin | |
rpoB | 761847 | p.Cys681Arg | missense_variant | 0.92 | rifampicin | Uncertain significance |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761864 | c.2058G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761876 | c.2070C>G | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.92 | rifampicin | |
rpoB | 761903 | c.2097T>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.93 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.93 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.93 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761951 | c.2145G>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762008 | c.2202C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762014 | c.2208C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762122 | c.2316C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762275 | c.2469C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762314 | c.2508C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762341 | c.2535G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 762374 | c.-996G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762380 | c.-990T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.98 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762407 | c.-963G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762410 | c.2604T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762452 | c.2646G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 762491 | c.2685T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 762512 | c.-858C>G | upstream_gene_variant | 0.88 | rifampicin | |
rpoC | 762527 | c.-843G>C | upstream_gene_variant | 0.95 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.94 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762537 | c.2731_2733delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762785 | p.Asp993Glu | missense_variant | 0.9 | rifampicin | Uncertain significance |
rpoB | 762786 | p.Val994Lys | missense_variant | 0.9 | rifampicin | |
rpoB | 762798 | p.Ala998Ser | missense_variant | 0.93 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 762820 | p.Phe1005Tyr | missense_variant | 0.97 | rifampicin | |
rpoB | 762827 | c.3021G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762879 | c.3073_3075delATGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762995 | c.3189G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763004 | c.3198G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763007 | c.3201C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763133 | c.-237G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763139 | c.-231C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763142 | c.-228C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763179 | c.-191C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763205 | c.-165G>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.91 | rifampicin | Not assoc w R - Interim |
rpoC | 763217 | c.-153G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763227 | p.Leu1141Met | missense_variant | 1.0 | rifampicin | |
rpoB | 763235 | p.Glu1143Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763241 | p.Glu1145Asp | missense_variant | 1.0 | rifampicin | |
rpoC | 763250 | c.-120C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763251 | c.-119C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763259 | c.-111G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763268 | c.3462C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763283 | c.3477T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763284 | c.-86C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763289 | c.-81C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763375 | c.6C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763396 | c.27A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763405 | c.36C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763417 | c.48C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763430 | c.61A>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 763433 | c.64_66delCAAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763443 | p.Tyr25Phe | missense_variant | 1.0 | rifampicin | |
rpoC | 763447 | c.78C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763703 | c.334_336delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763711 | c.342G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763768 | c.399C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763781 | p.Ser138Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763813 | c.444C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 763822 | c.453C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 763831 | c.462A>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763837 | c.468G>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763840 | c.471G>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763849 | c.480G>A | synonymous_variant | 0.98 | rifampicin | |
rpoC | 763855 | c.486C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763867 | c.498C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763870 | c.501C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763871 | p.Gly168Ser | missense_variant | 0.96 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.96 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763888 | c.519G>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 763910 | p.Leu181Met | missense_variant | 0.96 | rifampicin | |
rpoC | 763933 | c.564C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 763940 | p.Ala191Ser | missense_variant | 0.95 | rifampicin | Uncertain significance |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763947 | p.Ala193Val | missense_variant | 0.95 | rifampicin | Uncertain significance |
rpoC | 763951 | c.582G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 763960 | c.591T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 763978 | c.609C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 0.99 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764084 | p.Asn239Val | missense_variant | 0.98 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Gln | missense_variant | 0.98 | rifampicin | |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764147 | c.778_780delTCGinsGC | frameshift_variant&missense_variant | 0.95 | rifampicin | |
rpoC | 764153 | p.Gln262Lys | missense_variant | 0.95 | rifampicin | |
rpoC | 764156 | p.Lys263Arg | missense_variant | 0.95 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764203 | c.834G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764206 | p.Asp279Glu | missense_variant | 0.95 | rifampicin | |
rpoC | 764207 | p.Val280Thr | missense_variant | 0.95 | rifampicin | Uncertain significance |
rpoC | 764215 | c.846A>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764217 | p.Asn283Ser | missense_variant | 0.97 | rifampicin | |
rpoC | 764242 | c.873C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764245 | c.876C>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764248 | c.879C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764266 | c.897T>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoC | 764269 | c.900G>T | synonymous_variant | 0.93 | rifampicin | |
rpoC | 764272 | c.903G>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 764285 | p.Gly306Ser | missense_variant | 0.94 | rifampicin | |
rpoC | 764320 | c.951C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764338 | c.969G>A | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764383 | c.1014C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764387 | c.1018T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 0.96 | rifampicin | |
rpoC | 764410 | c.1041G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764485 | c.1116G>C | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764491 | c.1122G>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764500 | c.1131C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764578 | c.1209C>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764585 | c.1216_1218delCTCinsTG | frameshift_variant&missense_variant | 0.95 | rifampicin | |
rpoC | 764611 | c.1242G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764686 | c.1317C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764713 | c.1344G>A | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764746 | c.1377G>T | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764758 | c.1389C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764803 | c.1434C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 764857 | c.1488G>T | synonymous_variant | 0.97 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764875 | c.1506C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764878 | c.1509C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764887 | c.1518G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 764888 | c.1519_1521delTTGinsCC | frameshift_variant&missense_variant | 0.99 | rifampicin | |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764983 | c.1614T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765011 | c.1642_1644delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765016 | c.1647C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765055 | c.1686C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
rpoC | 765357 | p.Met663Thr | missense_variant | 0.9 | rifampicin | |
rpoC | 765359 | p.Ala664Thr | missense_variant | 0.9 | rifampicin | |
rpoC | 765367 | c.1998C>G | synonymous_variant | 0.93 | rifampicin | |
rpoC | 765397 | c.2028G>T | synonymous_variant | 0.93 | rifampicin | |
rpoC | 765402 | c.2035_2038delCTGG | frameshift_variant | 0.93 | rifampicin | |
rpoC | 765409 | c.2041_2042insCAGT | frameshift_variant | 0.93 | rifampicin | |
rpoC | 765425 | p.Lys686Glu | missense_variant | 0.91 | rifampicin | |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.9 | rifampicin | |
rpoC | 765452 | p.Ala695Arg | missense_variant | 0.9 | rifampicin | |
rpoC | 765458 | p.Ile697Val | missense_variant | 0.91 | rifampicin | Uncertain significance |
rpoC | 765466 | c.2097C>T | synonymous_variant | 0.92 | rifampicin | |
rpoC | 765478 | c.2109T>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 765496 | c.2127C>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 765547 | c.2178C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 765548 | c.2179_2181delAGCinsTCG | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.79 | rifampicin | |
rpoC | 765590 | p.Arg741Glu | missense_variant | 0.85 | rifampicin | |
rpoC | 765596 | p.Lys743Gln | missense_variant | 0.77 | rifampicin | |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.87 | rifampicin | |
rpoC | 765793 | c.2424C>G | synonymous_variant | 0.93 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.94 | rifampicin | |
rpoC | 765805 | c.2436C>G | synonymous_variant | 0.94 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 765875 | p.Val836Ile | missense_variant | 0.98 | rifampicin | Uncertain significance |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765937 | c.2568T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765947 | c.2578T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765961 | c.2592G>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765962 | c.2593_2595delTTGinsCT | frameshift_variant&synonymous_variant | 0.97 | rifampicin | |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765973 | c.2604C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766012 | c.2643C>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.88 | rifampicin | |
rpoC | 766270 | c.2901G>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.89 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.9 | rifampicin | |
rpoC | 766298 | p.Thr977Leu | missense_variant | 0.92 | rifampicin | |
rpoC | 766309 | c.2940G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
rpoC | 766315 | c.2946C>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 766321 | c.2952C>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 766324 | c.2955C>G | synonymous_variant | 0.92 | rifampicin | |
rpoC | 766333 | c.2964G>C | synonymous_variant | 0.93 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766363 | c.2994G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766369 | c.3000C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766411 | c.3042C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766423 | c.3054T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766428 | c.3060_3061insACC | conservative_inframe_insertion | 1.0 | rifampicin | |
rpoC | 766432 | c.3063T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766434 | c.3065_3066delAGinsGCAGC | missense_variant&conservative_inframe_insertion | 1.0 | rifampicin | |
rpoC | 766456 | c.3087C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766459 | c.3090G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766480 | c.3111C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766492 | c.3123T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766494 | p.Gly1042Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 766517 | p.Thr1050Ser | missense_variant | 0.97 | rifampicin | |
rpoC | 766522 | c.3153C>T | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766528 | c.3159T>G | synonymous_variant | 0.94 | rifampicin | |
rpoC | 766530 | p.Arg1054Gln | missense_variant | 0.87 | rifampicin | |
rpoC | 766540 | p.Asp1057Glu | missense_variant | 0.91 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.88 | rifampicin | |
rpoC | 766681 | c.3312C>T | synonymous_variant | 0.9 | rifampicin | |
rpoC | 766693 | c.3324C>T | synonymous_variant | 0.92 | rifampicin | |
rpoC | 766714 | c.3345G>C | synonymous_variant | 0.93 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 766733 | c.3364C>T | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766738 | c.3369G>T | synonymous_variant | 0.94 | rifampicin | |
rpoC | 766741 | c.3372G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766771 | c.3402G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766775 | p.Arg1136Lys | missense_variant | 1.0 | rifampicin | |
rpoC | 766801 | c.3432C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766846 | c.3477C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766858 | c.3489C>G | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766867 | c.3498C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766907 | c.3538C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766911 | p.Ile1181Thr | missense_variant | 0.97 | rifampicin | |
rpoC | 766915 | p.Asp1182Glu | missense_variant | 0.97 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 766942 | c.3573C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766951 | c.3582G>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766978 | c.3609C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766981 | c.3612T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767023 | c.3654C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767038 | c.3669G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767104 | c.3735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767155 | c.3786C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767161 | c.3792C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767162 | p.Asn1265Pro | missense_variant | 1.0 | rifampicin | |
rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767197 | c.3828G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 1.0 | rifampicin | |
mmpL5 | 775796 | c.2683_2685delTTTinsAG | frameshift_variant&stop_gained | 0.82 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775802 | p.Met893Ile | missense_variant | 0.5 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775817 | c.2664T>C | synonymous_variant | 0.87 | clofazimine | Not assoc w R - Interim |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775826 | c.2655G>C | synonymous_variant | 0.38 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775829 | c.2652C>G | synonymous_variant | 0.72 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775832 | c.2649C>G | synonymous_variant | 0.72 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775835 | c.2646C>G | synonymous_variant | 0.74 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775847 | c.2634G>C | synonymous_variant | 0.54 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775856 | c.2625T>C | synonymous_variant | 0.9 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775865 | c.2616T>G | synonymous_variant | 0.91 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775886 | c.2595A>C | synonymous_variant | 0.95 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775895 | c.2584_2586delATCinsCG | frameshift_variant&missense_variant | 0.5 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775898 | c.2583G>A | synonymous_variant | 0.5 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775904 | c.2577G>A | synonymous_variant | 0.61 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775907 | c.2572_2574delCTCinsTG | frameshift_variant&synonymous_variant | 0.61 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775910 | c.2571G>C | synonymous_variant | 0.51 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775913 | c.2566_2568delGCCinsTA | frameshift_variant&missense_variant | 0.6 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 0.96 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775939 | p.Ala848Ser | missense_variant | 0.47 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775943 | c.2538C>G | synonymous_variant | 0.65 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775946 | c.2535C>G | synonymous_variant | 0.78 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775951 | c.2530C>T | synonymous_variant | 0.86 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775955 | p.Ile842Met | missense_variant | 0.31 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.41 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.89 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775975 | p.Leu836Met | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775991 | c.2488_2490delGAGinsAC | frameshift_variant&missense_variant | 0.62 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775997 | c.2484T>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776000 | c.2481G>C | synonymous_variant | 0.61 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.9 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776015 | c.2464_2466delATCinsTG | frameshift_variant&missense_variant | 0.39 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776018 | c.2461_2463delCTGinsTC | frameshift_variant&synonymous_variant | 0.56 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776021 | c.2458_2460delGTGinsAC | frameshift_variant&missense_variant | 0.55 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776030 | c.2451G>C | synonymous_variant | 0.96 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776039 | c.2442C>T | synonymous_variant | 0.35 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776053 | p.Leu810Val | missense_variant | 0.66 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776060 | c.2421C>G | synonymous_variant | 0.91 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776072 | c.2409C>G | synonymous_variant | 0.71 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776075 | c.2406C>G | synonymous_variant | 0.69 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776078 | c.2403C>G | synonymous_variant | 0.93 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776081 | c.2400G>C | synonymous_variant | 0.6 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776087 | c.2394C>G | synonymous_variant | 0.93 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776093 | c.2388C>A | synonymous_variant | 0.67 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
rpsL | 781592 | c.33T>G | synonymous_variant | 0.86 | streptomycin | |
rpsL | 781595 | c.36T>C | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781598 | c.39G>T | synonymous_variant | 0.86 | streptomycin | |
rpsL | 781605 | p.Ile16Pro | missense_variant | 0.86 | streptomycin | |
rpsL | 781608 | c.49_51delAGTinsGC | frameshift_variant&missense_variant | 0.86 | streptomycin | Uncertain significance |
rpsL | 781616 | c.57C>G | synonymous_variant | 0.86 | streptomycin | |
rpsL | 781617 | p.Lys20Arg | missense_variant | 0.86 | streptomycin | |
rpsL | 781620 | p.Thr21Val | missense_variant | 0.86 | streptomycin | |
rpsL | 781625 | c.66G>C | synonymous_variant | 0.86 | streptomycin | |
rpsL | 781628 | c.69T>A | synonymous_variant | 0.87 | streptomycin | |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.88 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781652 | c.93T>C | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781658 | c.99A>G | synonymous_variant | 0.93 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781709 | c.150G>C | synonymous_variant | 0.98 | streptomycin | Not assoc w R - Interim |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781718 | c.159C>A | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.97 | streptomycin | |
rpsL | 781733 | c.174G>C | synonymous_variant | 0.97 | streptomycin | |
rpsL | 781735 | p.Ser59Thr | missense_variant | 0.97 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781763 | c.204C>G | synonymous_variant | 0.96 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.97 | streptomycin | |
rpsL | 781808 | c.249C>T | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781814 | c.255C>T | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781817 | c.258G>T | synonymous_variant | 0.97 | streptomycin | |
rpsL | 781832 | c.273T>G | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781859 | c.300T>C | synonymous_variant | 0.98 | streptomycin | Not assoc w R - Interim |
rpsL | 781865 | c.306G>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781880 | c.321C>G | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.98 | streptomycin | |
rpsL | 781904 | c.345C>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>C | upstream_gene_variant | 0.93 | linezolid | |
rplC | 800531 | c.-278T>C | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800537 | c.-272C>G | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800570 | c.-239C>G | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800574 | c.-235_-234delGTinsAC | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800579 | c.-230C>G | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800585 | c.-224T>C | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800594 | c.-215C>G | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800597 | c.-212A>C | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800600 | c.-209G>C | upstream_gene_variant | 0.95 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.96 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800633 | c.-176T>C | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800693 | c.-116A>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800702 | c.-107G>A | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.97 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800735 | c.-74C>G | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800762 | c.-47T>G | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800774 | c.-35C>T | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800799 | c.-10_-8delGGAinsC | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800807 | c.-2C>A | upstream_gene_variant | 0.94 | linezolid | |
rplC | 800814 | c.6A>T | synonymous_variant | 0.94 | linezolid | |
rplC | 800815 | c.7_9delCGAinsAG | frameshift_variant&synonymous_variant | 0.94 | linezolid | |
rplC | 800829 | c.21C>G | synonymous_variant | 0.95 | linezolid | |
rplC | 800832 | c.24T>C | synonymous_variant | 0.96 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.96 | linezolid | |
rplC | 800856 | c.48A>G | synonymous_variant | 0.98 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.98 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.98 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.98 | linezolid | |
rplC | 800877 | c.69A>C | synonymous_variant | 0.98 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.98 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.98 | linezolid | |
rplC | 800892 | c.84G>C | synonymous_variant | 0.98 | linezolid | |
rplC | 800904 | c.96G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800913 | c.105G>C | synonymous_variant | 0.98 | linezolid | |
rplC | 800916 | c.108A>C | synonymous_variant | 0.98 | linezolid | |
rplC | 800919 | c.111C>G | synonymous_variant | 0.98 | linezolid | |
rplC | 800931 | c.123G>T | synonymous_variant | 0.98 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.97 | linezolid | |
rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
rplC | 800981 | p.Ser58Asn | missense_variant | 1.0 | linezolid | |
rplC | 800985 | c.177A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800994 | c.186C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801008 | p.Thr67Lys | missense_variant | 1.0 | linezolid | |
rplC | 801019 | p.Thr71Glu | missense_variant | 1.0 | linezolid | |
rplC | 801027 | c.219C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801117 | c.309G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801127 | p.Ala107Thr | missense_variant | 1.0 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801156 | c.348T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801160 | c.352_353delTCinsAG | synonymous_variant | 1.0 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801180 | c.372C>G | synonymous_variant | 0.98 | linezolid | |
rplC | 801195 | c.387G>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801201 | c.393C>T | synonymous_variant | 0.96 | linezolid | |
rplC | 801210 | c.402T>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801228 | c.420T>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801229 | p.Ala141Thr | missense_variant | 0.98 | linezolid | |
rplC | 801252 | c.444G>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.98 | linezolid | |
rplC | 801267 | c.459A>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801273 | c.465C>G | synonymous_variant | 0.98 | linezolid | |
rplC | 801281 | p.Ala158Gly | missense_variant | 0.98 | linezolid | |
rplC | 801303 | c.495G>C | synonymous_variant | 0.98 | linezolid | |
rplC | 801309 | c.501C>G | synonymous_variant | 0.95 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.94 | linezolid | |
rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801330 | c.522G>C | synonymous_variant | 0.95 | linezolid | |
rplC | 801331 | c.523_525delGTGinsAC | frameshift_variant&missense_variant | 0.95 | linezolid | |
rplC | 801337 | p.Val177Thr | missense_variant | 0.95 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.95 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.95 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.9 | linezolid | |
rplC | 801385 | c.577C>T | synonymous_variant | 0.82 | linezolid | |
fbiC | 1303497 | c.567G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303506 | c.576C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303531 | p.Met201Leu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303551 | c.621G>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303971 | c.1041T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303977 | c.1047C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303980 | c.1050G>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303995 | c.1065C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303998 | c.1068T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304001 | c.1071C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304004 | c.1074A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304013 | c.1083G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304019 | c.1089C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304031 | c.1101C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304040 | c.1110C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304048 | p.Ala373Gly | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304106 | c.1176G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304118 | c.1188C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304127 | c.1197A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304133 | c.1203G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304571 | c.1641G>C | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304577 | c.1647C>T | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304607 | c.1677C>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304610 | c.1680C>G | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>A | synonymous_variant | 0.91 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304631 | c.1701C>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304652 | c.1722C>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304655 | c.1725C>T | synonymous_variant | 0.95 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304675 | p.Gly582Asp | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304709 | c.1779C>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.96 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304751 | c.1821C>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304763 | c.1833C>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304769 | c.1839C>T | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304772 | c.1842C>T | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304778 | c.1848T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>A | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304826 | c.1896G>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.94 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304835 | c.1905G>A | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304868 | c.1938G>A | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304871 | c.1941G>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304872 | c.1942_1944delAGCinsTCG | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304877 | c.1947T>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304887 | c.1957C>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304894 | p.Gly655Ala | missense_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304901 | c.1971C>G | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304910 | c.1980G>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304922 | c.1992C>T | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304931 | c.2001C>G | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304967 | c.2037G>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364667 | c.255T>C | synonymous_variant | 0.91 | pyrazinamide | |
sigE | 1364676 | c.264C>G | synonymous_variant | 0.92 | pyrazinamide | |
sigE | 1364703 | c.291G>C | synonymous_variant | 0.95 | pyrazinamide | |
sigE | 1364709 | c.297T>C | synonymous_variant | 0.95 | pyrazinamide | |
sigE | 1364712 | c.300T>C | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364718 | c.306C>T | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364727 | c.315C>T | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364736 | c.324T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364742 | c.330A>G | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364763 | c.351T>C | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364767 | c.355_357delAGGinsCC | frameshift_variant&missense_variant | 0.96 | pyrazinamide | Uncertain significance |
sigE | 1364772 | c.360G>C | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364778 | c.366G>C | synonymous_variant | 0.92 | pyrazinamide | |
sigE | 1364782 | c.370_372delGTCinsCG | frameshift_variant&missense_variant | 0.92 | pyrazinamide | Uncertain significance |
sigE | 1364790 | c.378T>C | synonymous_variant | 0.92 | pyrazinamide | |
sigE | 1364799 | c.387G>C | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364805 | c.393C>G | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364818 | c.406_408delCTAinsTG | frameshift_variant&stop_gained | 0.93 | pyrazinamide | Uncertain significance |
sigE | 1364832 | c.420C>G | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364835 | c.423C>G | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364847 | c.435G>C | synonymous_variant | 0.92 | pyrazinamide | |
sigE | 1364856 | c.444C>G | synonymous_variant | 0.91 | pyrazinamide | |
sigE | 1364862 | c.450C>G | synonymous_variant | 0.9 | pyrazinamide | |
sigE | 1364868 | c.456T>C | synonymous_variant | 0.88 | pyrazinamide | |
sigE | 1364877 | c.465G>A | synonymous_variant | 0.88 | pyrazinamide | |
sigE | 1364883 | c.471G>A | synonymous_variant | 0.92 | pyrazinamide | |
sigE | 1364886 | c.474G>A | synonymous_variant | 0.9 | pyrazinamide | |
sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 0.9 | pyrazinamide | Uncertain significance |
sigE | 1364892 | c.480C>G | synonymous_variant | 0.92 | pyrazinamide | |
sigE | 1364904 | p.Asp164Glu | missense_variant | 0.95 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.95 | pyrazinamide | |
sigE | 1364920 | p.Glu170Ser | missense_variant | 0.95 | pyrazinamide | |
sigE | 1364950 | c.538_540delGCAinsTG | frameshift_variant&stop_gained | 1.0 | pyrazinamide | Uncertain significance |
sigE | 1364956 | c.544C>T | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364961 | c.549A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364964 | c.552T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364976 | c.564T>C | synonymous_variant | 0.94 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364979 | c.567C>G | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1364980 | c.568_570delTTGinsCC | frameshift_variant&missense_variant | 0.93 | pyrazinamide | Uncertain significance |
sigE | 1364984 | p.Ala191Asp | missense_variant | 0.93 | pyrazinamide | |
sigE | 1364994 | c.582G>C | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1365000 | c.588G>A | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
sigE | 1365006 | c.594T>C | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1365015 | c.603G>C | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1365024 | c.612T>C | synonymous_variant | 0.93 | pyrazinamide | |
sigE | 1365042 | c.630G>C | synonymous_variant | 0.92 | pyrazinamide | |
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471936 | n.91A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471986 | n.141C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472019 | n.174G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472022 | n.178_181delGGAC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472030 | n.185delGinsCCTGCT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472033 | n.188A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472040 | n.195delTinsGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472043 | n.198T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472048 | n.203T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472279 | n.434T>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472287 | n.442C>T | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472297 | n.453_454delGT | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472303 | n.458_470delGGTTCTCTCGGATinsTGAGG | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473289 | n.1444T>G | non_coding_transcript_exon_variant | 0.99 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473290 | n.1445_1446insAA | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.99 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473696 | n.39T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473697 | n.40C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473699 | n.42A>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473743 | n.86C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473807 | n.150T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473811 | n.154C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473813 | n.156C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473814 | n.157A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473815 | n.158T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473816 | n.159C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473828 | n.171G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473829 | n.172G>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473830 | n.173T>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1473831 | n.174G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473833 | n.176G>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1473836 | n.179A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474174 | n.517A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474186 | n.529A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474202 | n.545T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474282 | n.625G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474287 | n.630delTinsCCC | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474293 | n.637_644delCCTCTCCG | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474303 | n.646A>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474306 | n.649A>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.653_654delTG | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474350 | n.693G>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474351 | n.694G>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474374 | n.717T>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474413 | n.756_757delACinsTAT | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474418 | n.761C>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474421 | n.764_767delGCGCinsA | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474437 | n.780_781delGAinsTTGGT | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474439 | n.782A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
linezolid | ||||||
rrl | 1474446 | n.789C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474452 | n.795C>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
linezolid | ||||||
rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474629 | n.972G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474636 | n.979A>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474637 | n.980C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474638 | n.981C>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474710 | n.1053delTinsACAA | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474720 | n.1063C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475031 | n.1374G>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475088 | n.1431A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
linezolid | ||||||
rrl | 1475202 | n.1545G>A | non_coding_transcript_exon_variant | 0.92 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475333 | n.1676T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475379 | n.1722G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475380 | n.1723C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475381 | n.1724G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475382 | n.1725A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475393 | n.1737_1738insGATG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475397 | n.1741_1745delCTCAC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475404 | n.1747A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475430 | n.1773T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475452 | n.1795C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475458 | n.1801C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475460 | n.1803A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475532 | n.1875A>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475545 | n.1888T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475602 | n.1945G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475603 | n.1946G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475606 | n.1949T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475613 | n.1956A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475615 | n.1958C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475626 | n.1969T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475627 | n.1970G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475628 | n.1971G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475629 | n.1972G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475637 | n.1980T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475639 | n.1982C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475643 | n.1986C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475647 | n.1990G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475707 | n.2050T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1475756 | n.2099T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475916 | n.2259C>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475991 | n.2334T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>G | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1476034 | n.2377C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476046 | n.2389G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476058 | n.2401T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476165 | n.2508T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476252 | n.2595T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476679 | n.3022T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476692 | n.3035T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476731 | n.3074G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476740 | n.3083G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476741 | n.3084G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476743 | n.3086A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476744 | n.3087G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476746 | n.3089T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476757 | n.3100T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476770 | n.3113T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1476771 | n.3114G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.73 | ethionamide | |
isoniazid | ||||||
inhA | 1673679 | c.-523T>C | upstream_gene_variant | 0.73 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1673682 | c.-520G>C | upstream_gene_variant | 0.75 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1673692 | c.-510C>G | upstream_gene_variant | 0.77 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1673697 | c.-505G>C | upstream_gene_variant | 0.77 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673710 | c.271_273delCTAinsAC | frameshift_variant&missense_variant | 0.77 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673716 | p.Ala93Lys | missense_variant | 0.77 | ethionamide | |
isoniazid | ||||||
inhA | 1673724 | c.-478A>G | upstream_gene_variant | 0.77 | ethionamide | |
isoniazid | ||||||
inhA | 1673727 | c.-475C>T | upstream_gene_variant | 0.77 | ethionamide | |
isoniazid | Uncertain significance | |||||
fabG1 | 1673733 | p.Met98Ile | missense_variant | 0.77 | ethionamide | |
isoniazid | ||||||
inhA | 1673736 | c.-466G>A | upstream_gene_variant | 0.77 | ethionamide | |
isoniazid | ||||||
inhA | 1673748 | c.-454A>G | upstream_gene_variant | 0.91 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673749 | p.Lys104Arg | missense_variant | 0.91 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673758 | p.Lys107Glu | missense_variant | 0.91 | ethionamide | |
isoniazid | ||||||
inhA | 1673784 | c.-418G>C | upstream_gene_variant | 0.95 | ethionamide | |
isoniazid | ||||||
inhA | 1673799 | c.-403T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673802 | c.-400A>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673805 | c.-397G>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1673808 | c.-394A>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674471 | c.270G>C | synonymous_variant | 0.87 | ethionamide | |
isoniazid | ||||||
inhA | 1674474 | c.273G>C | synonymous_variant | 0.87 | ethionamide | |
isoniazid | ||||||
inhA | 1674486 | c.285T>C | synonymous_variant | 0.87 | ethionamide | |
isoniazid | ||||||
inhA | 1674502 | c.301_303delACCinsTG | frameshift_variant&missense_variant | 0.87 | ethionamide | |
isoniazid | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.88 | ethionamide | |
isoniazid | ||||||
inhA | 1674513 | c.312C>G | synonymous_variant | 0.89 | ethionamide | |
isoniazid | ||||||
inhA | 1674534 | c.333G>A | synonymous_variant | 0.91 | ethionamide | |
isoniazid | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.95 | ethionamide | |
isoniazid | ||||||
inhA | 1674546 | c.345T>C | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.95 | ethionamide | |
isoniazid | ||||||
inhA | 1674550 | p.Ser117Ala | missense_variant | 0.95 | ethionamide | |
isoniazid | ||||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
inhA | 1674576 | c.375T>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
inhA | 1674579 | c.378G>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.94 | ethionamide | |
isoniazid | ||||||
inhA | 1674601 | p.Leu134Thr | missense_variant | 0.94 | ethionamide | |
isoniazid | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674654 | c.453G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674656 | p.Ser152Thr | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674669 | c.468G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674672 | c.471C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674711 | c.510G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674726 | c.525G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674737 | p.Ala179Val | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674741 | c.540C>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674742 | p.Lys181Pro | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674745 | p.Tyr182His | missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1674750 | c.549T>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674771 | c.570C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674786 | c.585G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674804 | c.603G>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
isoniazid | ||||||
inhA | 1674810 | c.609C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674813 | c.612C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674816 | c.615T>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674822 | c.621C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674825 | c.624C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674828 | c.627G>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674839 | p.Ala213Glu | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674846 | p.Ile215Met | missense_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674848 | p.Gln216Arg | missense_variant | 1.0 | ethionamide | |
isoniazid | Uncertain significance | |||||
inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674882 | c.681G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
inhA | 1674883 | p.Ile228Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1674892 | p.Asn231Asp | missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
inhA | 1674904 | p.Ala235Pro | missense_variant | 0.96 | ethionamide | |
isoniazid | ||||||
rpsA | 1833537 | c.-5_-1delACAATinsCCAC | upstream_gene_variant | 0.83 | pyrazinamide | |
rpsA | 1833547 | c.6G>A | synonymous_variant | 0.87 | pyrazinamide | |
rpsA | 1833554 | p.Thr5Ser | missense_variant | 0.88 | pyrazinamide | |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.92 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833595 | c.54T>G | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833616 | c.75A>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833628 | c.87G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1833634 | c.93G>A | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1833664 | c.123C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833676 | c.135A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833679 | c.138G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833685 | c.144G>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833691 | c.150G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833694 | c.153G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833697 | c.156C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833709 | c.168C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833733 | c.192C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833734 | p.Ala65Ser | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833793 | c.252C>T | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1833862 | c.321G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833892 | c.351G>A | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833894 | p.Ala118Glu | missense_variant | 0.97 | pyrazinamide | |
rpsA | 1833901 | c.360G>A | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.96 | pyrazinamide | |
rpsA | 1833949 | c.408T>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.96 | pyrazinamide | |
rpsA | 1833991 | c.450C>G | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834012 | c.471G>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.99 | pyrazinamide | |
rpsA | 1834093 | c.552G>C | synonymous_variant | 0.95 | pyrazinamide | |
rpsA | 1834094 | c.553C>T | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834105 | c.564C>T | synonymous_variant | 0.95 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.85 | pyrazinamide | |
rpsA | 1834234 | c.693G>T | synonymous_variant | 0.89 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.9 | pyrazinamide | |
rpsA | 1834261 | c.720A>G | synonymous_variant | 0.89 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.89 | pyrazinamide | |
rpsA | 1834282 | c.741C>T | synonymous_variant | 0.94 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.95 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.95 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834369 | c.828C>G | synonymous_variant | 0.99 | pyrazinamide | |
rpsA | 1834378 | c.837T>C | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834387 | c.846C>T | synonymous_variant | 0.99 | pyrazinamide | |
rpsA | 1834390 | c.849G>C | synonymous_variant | 0.99 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.99 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834432 | c.891G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834456 | c.915T>G | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834520 | p.Ala327Ser | missense_variant | 1.0 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
rpsA | 1834543 | c.1002C>G | synonymous_variant | 0.97 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.98 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G |