TB-Profiler

TB-Profiler result

Run: ERR4769521

This average coverage of the target regions is below the recommended 30x. Some mutations may not be detected due to low coverage.

Summary

Run ID: ERR4769521

Sample name:

Date: 2024-04-16T09:49:55.071572

Number of reads: 601911

Percentage reads mapped: 15.86

Median coverage: 3.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: RR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	0.94
lineage4.9	Euro-American (H37Rv-like)	None	0.94

Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin	rpoB	c.1327_1329delTTGinsCC	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
isoniazid
ethambutol	embB	p.Asp311Gly		Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid	fgd1	c.166_168delTCCinsGG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
delamanid	fgd1	c.202_204delCTGinsAC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.205_207delCTGinsGC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.730_732delAACinsGG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	c.1132_1134delGCGinsTC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	c.1135_1137delGCGinsAC	Assoc w R - Interim	Confers DLM-PMD cross-resistance
c.1189_1191delAAAinsCG	Assoc w R - Interim	Confers DLM-PMD cross-resistance
bedaquiline
linezolid

Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
fgd1	490948	c.166_168delTCCinsGG	frameshift_variant&missense_variant	0.94	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490948	c.166_168delTCCinsGG	frameshift_variant&missense_variant	0.94	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490984	c.202_204delCTGinsAC	frameshift_variant&missense_variant	0.98	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490984	c.202_204delCTGinsAC	frameshift_variant&missense_variant	0.98	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490987	c.205_207delCTGinsGC	frameshift_variant&missense_variant	0.98	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	490987	c.205_207delCTGinsGC	frameshift_variant&missense_variant	0.98	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491083	c.301_303delGTTinsAC	frameshift_variant&missense_variant	0.97	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491083	c.301_303delGTTinsAC	frameshift_variant&missense_variant	0.97	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491512	c.730_732delAACinsGG	frameshift_variant&missense_variant	0.79	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fgd1	491512	c.730_732delAACinsGG	frameshift_variant&missense_variant	0.79	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
rpoB	761133	c.1327_1329delTTGinsCC	frameshift_variant&missense_variant	1.0	rifampicin	Assoc w R - Interim	Expert rule: Non-silent variants in RRDR of rpoB
fbiC	1304062	c.1132_1134delGCGinsTC	frameshift_variant&missense_variant	1.0	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304062	c.1132_1134delGCGinsTC	frameshift_variant&missense_variant	1.0	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304065	c.1135_1137delGCGinsAC	frameshift_variant&missense_variant	1.0	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304065	c.1135_1137delGCGinsAC	frameshift_variant&missense_variant	1.0	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304119	c.1189_1191delAAAinsCG	frameshift_variant&missense_variant	1.0	delamanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
fbiC	1304119	c.1189_1191delAAAinsCG	frameshift_variant&missense_variant	1.0	pretomanid	Assoc w R - Interim	Confers DLM-PMD cross-resistance
embB	4247445	p.Asp311Gly	missense_variant	0.9	ethambutol		Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
dnaA	660	c.660G>C	synonymous_variant	0.95	isoniazid	Not assoc w R - Interim
dnaA	663	c.663A>G	synonymous_variant	0.9	isoniazid	Not assoc w R - Interim
dnaA	672	c.672T>C	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
dnaA	678	c.678A>G	synonymous_variant	0.93	isoniazid	Not assoc w R - Interim
dnaA	690	c.690G>C	synonymous_variant	0.91	isoniazid
dnaA	693	c.693A>G	synonymous_variant	0.94	isoniazid	Not assoc w R - Interim
dnaA	705	c.705A>G	synonymous_variant	0.94	isoniazid
dnaA	708	c.708T>C	synonymous_variant	0.94	isoniazid
dnaA	714	c.714C>G	synonymous_variant	0.94	isoniazid	Not assoc w R - Interim
dnaA	741	c.741T>C	synonymous_variant	0.93	isoniazid	Not assoc w R - Interim
dnaA	744	c.744C>T	synonymous_variant	0.93	isoniazid
dnaA	747	c.747G>C	synonymous_variant	0.94	isoniazid
dnaA	750	c.750C>G	synonymous_variant	0.94	isoniazid
dnaA	756	c.756T>C	synonymous_variant	0.93	isoniazid
dnaA	767	p.Val256Ala	missense_variant	0.92	isoniazid
dnaA	769	c.769_771delGCAinsTC	frameshift_variant&missense_variant	0.91	isoniazid	Uncertain significance
dnaA	777	c.777A>G	synonymous_variant	0.93	isoniazid
dnaA	793	c.793_795delGTAinsAC	frameshift_variant&missense_variant	0.91	isoniazid	Uncertain significance
dnaA	805	c.805T>C	synonymous_variant	0.93	isoniazid
dnaA	822	c.822A>G	synonymous_variant	0.92	isoniazid
dnaA	828	c.828T>C	synonymous_variant	0.91	isoniazid	Not assoc w R - Interim
dnaA	831	c.831A>G	synonymous_variant	0.91	isoniazid
dnaA	837	c.837A>G	synonymous_variant	0.91	isoniazid
dnaA	840	c.840G>A	synonymous_variant	0.91	isoniazid
dnaA	843	c.843T>C	synonymous_variant	0.91	isoniazid	Not assoc w R - Interim
dnaA	846	c.846T>C	synonymous_variant	0.89	isoniazid
dnaA	849	c.849A>G	synonymous_variant	0.91	isoniazid
dnaA	852	c.852G>A	synonymous_variant	0.91	isoniazid	Not assoc w R - Interim
dnaA	877	c.877T>C	synonymous_variant	0.96	isoniazid
dnaA	885	c.885T>C	synonymous_variant	0.96	isoniazid
dnaA	897	c.897A>G	synonymous_variant	0.96	isoniazid
dnaA	909	c.909A>C	synonymous_variant	0.98	isoniazid	Not assoc w R - Interim
dnaA	912	c.912T>C	synonymous_variant	0.98	isoniazid
dnaA	918	c.918C>G	synonymous_variant	1.0	isoniazid
dnaA	921	c.921A>C	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	927	c.927G>A	synonymous_variant	1.0	isoniazid
dnaA	933	c.933C>G	synonymous_variant	1.0	isoniazid
dnaA	955	c.955_957delAGAinsCG	frameshift_variant&synonymous_variant	1.0	isoniazid	Uncertain significance
dnaA	963	c.963C>G	synonymous_variant	1.0	isoniazid
dnaA	966	c.966T>C	synonymous_variant	1.0	isoniazid
dnaA	975	c.975G>C	synonymous_variant	1.0	isoniazid
dnaA	976	c.976C>T	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
dnaA	984	c.984T>C	synonymous_variant	0.97	isoniazid	Not assoc w R - Interim
dnaA	990	c.990A>C	synonymous_variant	0.97	isoniazid
dnaA	993	c.993A>G	synonymous_variant	0.97	isoniazid
dnaA	996	c.996A>G	synonymous_variant	0.97	isoniazid
dnaA	1002	c.1002G>A	synonymous_variant	0.97	isoniazid
dnaA	1014	c.1014C>G	synonymous_variant	0.97	isoniazid
dnaA	1020	c.1020C>G	synonymous_variant	0.97	isoniazid
dnaA	1024	c.1024T>C	synonymous_variant	0.96	isoniazid
dnaA	1035	c.1035A>G	synonymous_variant	0.95	isoniazid
dnaA	1038	c.1038A>G	synonymous_variant	0.94	isoniazid
dnaA	1047	p.Glu349Asp	missense_variant	0.9	isoniazid
dnaA	1068	c.1068T>C	synonymous_variant	0.9	isoniazid
dnaA	1071	c.1071C>G	synonymous_variant	0.9	isoniazid
dnaA	1077	c.1077A>G	synonymous_variant	0.9	isoniazid
dnaA	1092	c.1092T>C	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
dnaA	1098	c.1098A>G	synonymous_variant	0.95	isoniazid
dnaA	1104	c.1104T>C	synonymous_variant	0.95	isoniazid
dnaA	1110	c.1110T>C	synonymous_variant	0.96	isoniazid
dnaA	1113	c.1113A>G	synonymous_variant	0.96	isoniazid
dnaA	1128	c.1128G>C	synonymous_variant	0.98	isoniazid
dnaA	1152	c.1152A>G	synonymous_variant	1.0	isoniazid
dnaA	1153	c.1153T>C	synonymous_variant	1.0	isoniazid
dnaA	1161	c.1161A>G	synonymous_variant	1.0	isoniazid
dnaA	1164	c.1164A>C	synonymous_variant	1.0	isoniazid
dnaA	1167	c.1167A>G	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
dnaA	1173	c.1174_1177delAAAG	frameshift_variant	1.0	isoniazid	Uncertain significance
dnaA	1179	c.1179_1180insGTCA	frameshift_variant	1.0	isoniazid	Uncertain significance
dnaA	1191	c.1191T>C	synonymous_variant	0.98	isoniazid
dnaA	1194	c.1194G>C	synonymous_variant	0.98	isoniazid
dnaA	1197	c.1197T>G	synonymous_variant	0.98	isoniazid
dnaA	1203	c.1203T>C	synonymous_variant	0.98	isoniazid
dnaA	1210	p.Ala404Ser	missense_variant	0.98	isoniazid
dnaA	1215	c.1215C>T	synonymous_variant	0.95	isoniazid
dnaA	1220	p.Asn407Ser	missense_variant	0.95	isoniazid
dnaA	1230	c.1230A>G	synonymous_variant	0.96	isoniazid
dnaA	1242	c.1242G>C	synonymous_variant	0.95	isoniazid
dnaA	1243	p.Thr415Ala	missense_variant	0.95	isoniazid	Uncertain significance
dnaA	1254	c.1254T>C	synonymous_variant	0.93	isoniazid
dnaA	1266	c.1266A>G	synonymous_variant	0.91	isoniazid
gyrB	6178	c.939C>T	synonymous_variant	0.97	levofloxacin
gyrB	6178	c.939C>T	synonymous_variant	0.97	moxifloxacin
gyrB	6190	c.951A>G	synonymous_variant	0.97	levofloxacin
gyrB	6190	c.951A>G	synonymous_variant	0.97	moxifloxacin
gyrB	6203	p.Ser322Ala	missense_variant	0.97	levofloxacin
gyrB	6203	p.Ser322Ala	missense_variant	0.97	moxifloxacin
gyrB	6208	c.969G>A	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6208	c.969G>A	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6214	c.975G>C	synonymous_variant	0.97	levofloxacin
gyrB	6214	c.975G>C	synonymous_variant	0.97	moxifloxacin
gyrB	6215	c.976_978delTCGinsAGC	synonymous_variant	0.97	levofloxacin
gyrB	6215	c.976_978delTCGinsAGC	synonymous_variant	0.97	moxifloxacin
gyrB	6223	c.984G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6223	c.984G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6238	c.999G>A	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6242	p.Arg335Lys	missense_variant	0.98	levofloxacin
gyrB	6242	p.Arg335Lys	missense_variant	0.98	moxifloxacin
gyrB	6250	c.1011A>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6250	c.1011A>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6253	c.1014G>C	synonymous_variant	0.98	levofloxacin
gyrB	6253	c.1014G>C	synonymous_variant	0.98	moxifloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.97	levofloxacin
gyrB	6280	c.1041T>C	synonymous_variant	0.97	moxifloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.98	levofloxacin
gyrB	6286	c.1047T>C	synonymous_variant	0.98	moxifloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.98	levofloxacin
gyrB	6292	c.1053G>C	synonymous_variant	0.98	moxifloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.98	levofloxacin
gyrB	6295	c.1056A>G	synonymous_variant	0.98	moxifloxacin
gyrB	6307	c.1068T>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6307	c.1068T>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	6310	c.-992G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6310	c.-992G>C	upstream_gene_variant	0.98	moxifloxacin
gyrB	6319	c.1080G>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6319	c.1080G>C	synonymous_variant	0.97	moxifloxacin
gyrA	6325	c.-977C>G	upstream_gene_variant	0.95	levofloxacin
gyrA	6325	c.-977C>G	upstream_gene_variant	0.95	moxifloxacin
gyrB	6326	p.Ser363Ala	missense_variant	0.97	levofloxacin
gyrB	6326	p.Ser363Ala	missense_variant	0.97	moxifloxacin
gyrB	6346	c.1107C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6346	c.1107C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6362	c.1123_1125delTTGinsCC	frameshift_variant&missense_variant	1.0	levofloxacin	Uncertain significance
gyrB	6362	c.1123_1125delTTGinsCC	frameshift_variant&missense_variant	1.0	moxifloxacin
gyrA	6379	c.-923C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6379	c.-923C>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6382	c.-920A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6388	c.-914T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6397	c.1158G>A	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrB	6397	c.1158G>A	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrB	6398	p.Val387Ile	missense_variant	1.0	levofloxacin
gyrB	6398	p.Val387Ile	missense_variant	1.0	moxifloxacin
gyrA	6403	c.-899T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6403	c.-899T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6416	p.Thr393Gly	missense_variant	1.0	levofloxacin
gyrB	6416	p.Thr393Gly	missense_variant	1.0	moxifloxacin
gyrA	6427	c.-875T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6427	c.-875T>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6430	c.-872A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6430	c.-872A>G	upstream_gene_variant	1.0	moxifloxacin
gyrB	6440	p.Thr401Ala	missense_variant	1.0	levofloxacin
gyrB	6440	p.Thr401Ala	missense_variant	1.0	moxifloxacin
gyrB	6445	p.Asp402Glu	missense_variant	1.0	levofloxacin	Uncertain significance
gyrB	6445	p.Asp402Glu	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrB	6452	p.Val405Thr	missense_variant	1.0	levofloxacin
gyrB	6452	p.Val405Thr	missense_variant	1.0	moxifloxacin
gyrA	6469	c.-833T>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6469	c.-833T>G	upstream_gene_variant	0.98	moxifloxacin
gyrA	6472	c.-830G>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6472	c.-830G>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6475	c.-827C>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6475	c.-827C>G	upstream_gene_variant	0.98	moxifloxacin
gyrA	6478	c.-824G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6478	c.-824G>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6484	c.-818A>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6484	c.-818A>G	upstream_gene_variant	0.98	moxifloxacin
gyrB	6487	c.1248C>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6487	c.1248C>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	6490	c.-812T>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6490	c.-812T>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6496	c.-806G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6496	c.-806G>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6499	c.-803A>G	upstream_gene_variant	0.98	levofloxacin
gyrA	6499	c.-803A>G	upstream_gene_variant	0.98	moxifloxacin
gyrA	6508	c.-794A>G	upstream_gene_variant	0.95	levofloxacin
gyrA	6508	c.-794A>G	upstream_gene_variant	0.95	moxifloxacin
gyrA	6511	c.-791A>T	upstream_gene_variant	0.95	levofloxacin
gyrA	6511	c.-791A>T	upstream_gene_variant	0.95	moxifloxacin
gyrA	6523	c.-779G>T	upstream_gene_variant	0.96	levofloxacin
gyrA	6523	c.-779G>T	upstream_gene_variant	0.96	moxifloxacin
gyrA	6547	c.-755T>C	upstream_gene_variant	0.95	levofloxacin
gyrA	6547	c.-755T>C	upstream_gene_variant	0.95	moxifloxacin
gyrA	6550	c.-752A>C	upstream_gene_variant	0.95	levofloxacin
gyrA	6550	c.-752A>C	upstream_gene_variant	0.95	moxifloxacin
gyrB	6551	c.1312T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrB	6551	c.1312T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	6571	c.-731T>C	upstream_gene_variant	0.94	levofloxacin
gyrA	6571	c.-731T>C	upstream_gene_variant	0.94	moxifloxacin
gyrB	6577	c.1338T>C	synonymous_variant	0.92	levofloxacin	Not assoc w R - Interim
gyrB	6577	c.1338T>C	synonymous_variant	0.92	moxifloxacin	Not assoc w R - Interim
gyrA	6583	c.-719G>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6583	c.-719G>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6604	c.-698G>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6604	c.-698G>C	upstream_gene_variant	0.93	moxifloxacin
gyrB	6608	p.Val457Ile	missense_variant	0.93	levofloxacin
gyrB	6608	p.Val457Ile	missense_variant	0.93	moxifloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6613	c.-689A>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6616	c.-686A>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6619	c.-683T>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6619	c.-683T>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	0.93	levofloxacin
gyrA	6622	c.-680C>T	upstream_gene_variant	0.93	moxifloxacin
gyrA	6628	c.-674C>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6628	c.-674C>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6634	c.-668T>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	0.93	levofloxacin
gyrA	6637	c.-665T>G	upstream_gene_variant	0.93	moxifloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	0.93	levofloxacin
gyrA	6640	c.-662A>C	upstream_gene_variant	0.93	moxifloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.94	levofloxacin
gyrA	6643	c.-659A>G	upstream_gene_variant	0.94	moxifloxacin
gyrA	6649	c.-653T>G	upstream_gene_variant	0.94	levofloxacin
gyrA	6649	c.-653T>G	upstream_gene_variant	0.94	moxifloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6655	c.-647T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6673	c.-629A>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6676	c.-626T>G	upstream_gene_variant	0.97	moxifloxacin
gyrB	6680	c.1441C>T	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6680	c.1441C>T	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	6700	c.-602T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6700	c.-602T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6703	c.-599G>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6709	c.-593A>G	upstream_gene_variant	0.97	moxifloxacin
gyrA	6712	c.-590G>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6712	c.-590G>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6730	c.-572A>G	upstream_gene_variant	0.96	levofloxacin
gyrA	6730	c.-572A>G	upstream_gene_variant	0.96	moxifloxacin
gyrA	6733	c.-569G>A	upstream_gene_variant	0.97	levofloxacin
gyrA	6733	c.-569G>A	upstream_gene_variant	0.97	moxifloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6742	c.-560A>G	upstream_gene_variant	0.97	moxifloxacin
gyrB	6745	c.1506T>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6745	c.1506T>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	6760	c.-542G>C	upstream_gene_variant	0.98	levofloxacin
gyrA	6760	c.-542G>C	upstream_gene_variant	0.98	moxifloxacin
gyrA	6763	c.-539G>A	upstream_gene_variant	0.98	levofloxacin
gyrA	6763	c.-539G>A	upstream_gene_variant	0.98	moxifloxacin
gyrA	6775	c.-527G>T	upstream_gene_variant	0.98	levofloxacin
gyrA	6775	c.-527G>T	upstream_gene_variant	0.98	moxifloxacin
gyrB	6793	c.1554T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6793	c.1554T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6797	p.Gly520Ser	missense_variant	0.97	levofloxacin
gyrB	6797	p.Gly520Ser	missense_variant	0.97	moxifloxacin
gyrB	6811	c.1572C>T	synonymous_variant	0.96	levofloxacin
gyrB	6811	c.1572C>T	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrB	6824	c.1585C>T	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6824	c.1585C>T	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	6844	c.-458T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6844	c.-458T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	0.97	levofloxacin
gyrA	6853	c.-449A>G	upstream_gene_variant	0.97	moxifloxacin
gyrB	6856	c.1617T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6856	c.1617T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrB	6859	c.1620T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrB	6860	p.Ser541Ala	missense_variant	0.97	levofloxacin
gyrB	6860	p.Ser541Ala	missense_variant	0.97	moxifloxacin
gyrA	6869	c.-433T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6869	c.-433T>C	upstream_gene_variant	0.97	moxifloxacin
gyrA	6872	c.-430T>C	upstream_gene_variant	0.97	levofloxacin
gyrA	6872	c.-430T>C	upstream_gene_variant	0.97	moxifloxacin
gyrB	6878	c.1639T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrB	6878	c.1639T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrB	6881	c.1642T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrB	6881	c.1642T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrB	6896	p.Arg553Lys	missense_variant	0.99	levofloxacin
gyrB	6896	p.Arg553Lys	missense_variant	0.99	moxifloxacin
gyrB	6919	c.1680T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6919	c.1680T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6922	c.1683G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6922	c.1683G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6924	p.Phe562Tyr	missense_variant	0.98	levofloxacin
gyrB	6924	p.Phe562Tyr	missense_variant	0.98	moxifloxacin
gyrB	6926	c.1687T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6926	c.1687T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrB	6931	c.1692A>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrB	6931	c.1692A>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	6940	c.-362G>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6940	c.-362G>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6949	c.-353A>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6949	c.-353A>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	6955	c.-347G>A	upstream_gene_variant	1.0	levofloxacin
gyrA	6955	c.-347G>A	upstream_gene_variant	1.0	moxifloxacin
gyrA	6961	c.-341G>A	upstream_gene_variant	1.0	levofloxacin
gyrA	6961	c.-341G>A	upstream_gene_variant	1.0	moxifloxacin
gyrA	6967	c.-335T>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6967	c.-335T>C	upstream_gene_variant	1.0	moxifloxacin
gyrB	6970	p.Asp577Glu	missense_variant	1.0	levofloxacin
gyrB	6970	p.Asp577Glu	missense_variant	1.0	moxifloxacin
gyrA	6982	c.-320A>C	upstream_gene_variant	1.0	levofloxacin
gyrA	6982	c.-320A>C	upstream_gene_variant	1.0	moxifloxacin
gyrA	6988	c.-314C>G	upstream_gene_variant	1.0	levofloxacin
gyrA	6988	c.-314C>G	upstream_gene_variant	1.0	moxifloxacin
gyrA	7000	c.-302C>T	upstream_gene_variant	1.0	levofloxacin
gyrA	7000	c.-302C>T	upstream_gene_variant	1.0	moxifloxacin
gyrB	7005	p.Gly589Ala	missense_variant	0.95	levofloxacin
gyrB	7005	p.Gly589Ala	missense_variant	0.95	moxifloxacin
gyrA	7015	c.-287G>A	upstream_gene_variant	0.92	levofloxacin
gyrA	7015	c.-287G>A	upstream_gene_variant	0.92	moxifloxacin
gyrA	7021	c.-281G>C	upstream_gene_variant	0.92	levofloxacin
gyrA	7021	c.-281G>C	upstream_gene_variant	0.92	moxifloxacin
gyrA	7362	p.Glu21Gln	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7362	p.Glu21Gln	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7394	c.93T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7394	c.93T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.96	levofloxacin
gyrA	7427	c.126G>C	synonymous_variant	0.96	moxifloxacin
gyrA	7451	c.150C>G	synonymous_variant	0.97	levofloxacin
gyrA	7451	c.150C>G	synonymous_variant	0.97	moxifloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.97	levofloxacin
gyrA	7457	c.156T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7472	c.171T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7472	c.171T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7475	c.174A>C	synonymous_variant	0.97	levofloxacin
gyrA	7475	c.174A>C	synonymous_variant	0.97	moxifloxacin
gyrA	7480	p.Phe60Tyr	missense_variant	0.97	levofloxacin
gyrA	7480	p.Phe60Tyr	missense_variant	0.97	moxifloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.97	levofloxacin
gyrA	7484	c.183T>C	synonymous_variant	0.97	moxifloxacin
gyrA	7487	c.186C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7487	c.186C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	7490	c.189C>T	synonymous_variant	0.97	levofloxacin
gyrA	7490	c.189C>T	synonymous_variant	0.97	moxifloxacin
gyrA	7496	c.195C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	7496	c.195C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	7499	c.198G>C	synonymous_variant	0.97	levofloxacin
gyrA	7499	c.198G>C	synonymous_variant	0.97	moxifloxacin
gyrA	7511	c.210C>T	synonymous_variant	0.98	levofloxacin
gyrA	7511	c.210C>T	synonymous_variant	0.98	moxifloxacin
gyrA	7514	c.213C>G	synonymous_variant	0.98	levofloxacin
gyrA	7514	c.213C>G	synonymous_variant	0.98	moxifloxacin
gyrA	7517	c.216G>A	synonymous_variant	0.98	levofloxacin
gyrA	7517	c.216G>A	synonymous_variant	0.98	moxifloxacin
gyrA	7526	c.225G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	7526	c.225G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	7529	c.228G>C	synonymous_variant	0.98	levofloxacin
gyrA	7529	c.228G>C	synonymous_variant	0.98	moxifloxacin
gyrA	7532	c.231T>G	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	7532	c.231T>G	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7541	c.240C>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7568	c.267C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7568	c.267C>T	synonymous_variant	1.0	moxifloxacin
gyrA	7585	p.Ser95Thr	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	7585	p.Ser95Thr	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	7592	c.291G>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7592	c.291G>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7595	c.294C>G	synonymous_variant	0.99	levofloxacin
gyrA	7595	c.294C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7607	c.306C>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7607	c.306C>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7626	c.325C>T	synonymous_variant	0.99	levofloxacin
gyrA	7626	c.325C>T	synonymous_variant	0.99	moxifloxacin
gyrA	7631	c.330G>C	synonymous_variant	0.99	levofloxacin
gyrA	7631	c.330G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7637	c.336C>G	synonymous_variant	0.99	levofloxacin
gyrA	7637	c.336C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7658	c.357A>G	synonymous_variant	0.99	levofloxacin
gyrA	7658	c.357A>G	synonymous_variant	0.99	moxifloxacin
gyrA	7664	c.363T>C	synonymous_variant	0.99	levofloxacin
gyrA	7664	c.363T>C	synonymous_variant	0.99	moxifloxacin
gyrA	7670	c.369A>G	synonymous_variant	0.99	levofloxacin
gyrA	7670	c.369A>G	synonymous_variant	0.99	moxifloxacin
gyrA	7676	c.375G>C	synonymous_variant	0.99	levofloxacin
gyrA	7676	c.375G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7679	c.378G>C	synonymous_variant	0.99	levofloxacin
gyrA	7679	c.378G>C	synonymous_variant	0.99	moxifloxacin
gyrA	7697	c.396C>G	synonymous_variant	0.99	levofloxacin
gyrA	7697	c.396C>G	synonymous_variant	0.99	moxifloxacin
gyrA	7700	c.399G>A	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	7700	c.399G>A	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	7710	c.409T>C	synonymous_variant	0.99	levofloxacin
gyrA	7710	c.409T>C	synonymous_variant	0.99	moxifloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.99	levofloxacin
gyrA	7728	c.427_429delAGGinsCC	frameshift_variant&missense_variant	0.99	moxifloxacin
gyrA	7748	c.447A>C	synonymous_variant	0.99	levofloxacin
gyrA	7748	c.447A>C	synonymous_variant	0.99	moxifloxacin
gyrA	7758	p.Ile153Val	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	7758	p.Ile153Val	missense_variant	1.0	moxifloxacin
gyrA	7763	c.462T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7763	c.462T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7769	c.468C>T	synonymous_variant	1.0	levofloxacin
gyrA	7769	c.468C>T	synonymous_variant	1.0	moxifloxacin
gyrA	7784	c.483A>G	synonymous_variant	1.0	levofloxacin
gyrA	7784	c.483A>G	synonymous_variant	1.0	moxifloxacin
gyrA	7787	c.486G>A	synonymous_variant	1.0	levofloxacin
gyrA	7787	c.486G>A	synonymous_variant	1.0	moxifloxacin
gyrA	7799	c.498A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7799	c.498A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7802	c.501C>G	synonymous_variant	1.0	levofloxacin
gyrA	7802	c.501C>G	synonymous_variant	1.0	moxifloxacin
gyrA	7814	c.513C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7814	c.513C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7821	c.520C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7821	c.520C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7832	c.531G>C	synonymous_variant	1.0	levofloxacin
gyrA	7832	c.531G>C	synonymous_variant	1.0	moxifloxacin
gyrA	7835	c.534A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7835	c.534A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7841	c.540C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	7841	c.540C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	7859	c.558A>C	synonymous_variant	1.0	levofloxacin
gyrA	7859	c.558A>C	synonymous_variant	1.0	moxifloxacin
gyrA	7865	c.564T>C	synonymous_variant	1.0	levofloxacin
gyrA	7865	c.564T>C	synonymous_variant	1.0	moxifloxacin
gyrA	7886	c.585T>C	synonymous_variant	1.0	levofloxacin
gyrA	7886	c.585T>C	synonymous_variant	1.0	moxifloxacin
gyrA	7892	c.591G>C	synonymous_variant	1.0	levofloxacin
gyrA	7892	c.591G>C	synonymous_variant	1.0	moxifloxacin
gyrA	7898	p.Asp199Glu	missense_variant	1.0	levofloxacin
gyrA	7898	p.Asp199Glu	missense_variant	1.0	moxifloxacin
gyrA	8121	c.820T>C	synonymous_variant	0.93	levofloxacin
gyrA	8121	c.820T>C	synonymous_variant	0.93	moxifloxacin
gyrA	8129	c.828T>C	synonymous_variant	0.96	levofloxacin
gyrA	8129	c.828T>C	synonymous_variant	0.96	moxifloxacin
gyrA	8156	c.855T>C	synonymous_variant	0.97	levofloxacin
gyrA	8156	c.855T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8168	c.867A>G	synonymous_variant	0.98	levofloxacin
gyrA	8168	c.867A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8177	c.876A>C	synonymous_variant	0.98	levofloxacin
gyrA	8177	c.876A>C	synonymous_variant	0.98	moxifloxacin
gyrA	8187	c.886_888delCTGinsAC	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8187	c.886_888delCTGinsAC	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8198	c.897T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8198	c.897T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8199	p.Ser300Ala	missense_variant	0.98	levofloxacin
gyrA	8199	p.Ser300Ala	missense_variant	0.98	moxifloxacin
gyrA	8207	c.906T>C	synonymous_variant	0.98	levofloxacin
gyrA	8207	c.906T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.98	levofloxacin
gyrA	8210	c.909G>A	synonymous_variant	0.98	moxifloxacin
gyrA	8219	c.918T>C	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8219	c.918T>C	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8225	c.924T>C	synonymous_variant	0.99	levofloxacin
gyrA	8225	c.924T>C	synonymous_variant	0.99	moxifloxacin
gyrA	8234	c.933T>G	synonymous_variant	0.99	levofloxacin	Not assoc w R - Interim
gyrA	8234	c.933T>G	synonymous_variant	0.99	moxifloxacin	Not assoc w R - Interim
gyrA	8235	c.934_936delTTAinsCG	frameshift_variant&missense_variant	0.99	levofloxacin
gyrA	8235	c.934_936delTTAinsCG	frameshift_variant&missense_variant	0.99	moxifloxacin
gyrA	8253	p.Ile318Leu	missense_variant	1.0	levofloxacin
gyrA	8253	p.Ile318Leu	missense_variant	1.0	moxifloxacin
gyrA	8258	c.957G>A	synonymous_variant	1.0	levofloxacin
gyrA	8258	c.957G>A	synonymous_variant	1.0	moxifloxacin
gyrA	8264	c.963T>C	synonymous_variant	1.0	levofloxacin
gyrA	8264	c.963T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8267	c.966G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8267	c.966G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8283	c.982_984delATCinsCG	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8283	c.982_984delATCinsCG	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8288	c.987T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8288	c.987T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8294	c.993T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8324	c.1023T>C	synonymous_variant	0.99	levofloxacin
gyrA	8324	c.1023T>C	synonymous_variant	0.99	moxifloxacin
gyrA	8339	c.1038A>C	synonymous_variant	0.99	levofloxacin
gyrA	8339	c.1038A>C	synonymous_variant	0.99	moxifloxacin
gyrA	8357	c.1056G>C	synonymous_variant	0.99	levofloxacin
gyrA	8357	c.1056G>C	synonymous_variant	0.99	moxifloxacin
gyrA	8366	c.1065G>C	synonymous_variant	0.98	levofloxacin
gyrA	8366	c.1065G>C	synonymous_variant	0.98	moxifloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.98	levofloxacin
gyrA	8382	p.Leu361Met	missense_variant	0.98	moxifloxacin
gyrA	8390	c.1089C>G	synonymous_variant	0.98	levofloxacin
gyrA	8390	c.1089C>G	synonymous_variant	0.98	moxifloxacin
gyrA	8391	c.1090_1092delTATinsCC	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8391	c.1090_1092delTATinsCC	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8399	c.1098T>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8399	c.1098T>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8402	c.1101C>T	synonymous_variant	0.98	levofloxacin
gyrA	8402	c.1101C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8405	c.1104C>T	synonymous_variant	0.98	levofloxacin
gyrA	8405	c.1104C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8408	c.1107A>G	synonymous_variant	0.98	levofloxacin
gyrA	8408	c.1107A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8417	c.1116C>G	synonymous_variant	0.96	levofloxacin
gyrA	8417	c.1116C>G	synonymous_variant	0.96	moxifloxacin
gyrA	8420	c.1119T>C	synonymous_variant	0.96	levofloxacin
gyrA	8420	c.1119T>C	synonymous_variant	0.96	moxifloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.98	levofloxacin
gyrA	8453	c.1152A>C	synonymous_variant	0.98	moxifloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.98	levofloxacin
gyrA	8459	c.1158G>A	synonymous_variant	0.98	moxifloxacin
gyrA	8462	c.1161A>G	synonymous_variant	0.98	levofloxacin
gyrA	8462	c.1161A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.98	levofloxacin
gyrA	8471	c.1170T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.98	levofloxacin
gyrA	8480	c.1179C>T	synonymous_variant	0.98	moxifloxacin
gyrA	8486	c.1185T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8486	c.1185T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8489	c.1188A>G	synonymous_variant	0.97	levofloxacin
gyrA	8489	c.1188A>G	synonymous_variant	0.97	moxifloxacin
gyrA	8501	c.1200G>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8501	c.1200G>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8504	c.1203G>C	synonymous_variant	0.97	levofloxacin
gyrA	8504	c.1203G>C	synonymous_variant	0.97	moxifloxacin
gyrA	8513	c.1212C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8513	c.1212C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8516	c.1215T>C	synonymous_variant	0.97	levofloxacin
gyrA	8516	c.1215T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8519	c.1218A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8519	c.1218A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8520	c.1219C>T	synonymous_variant	0.97	levofloxacin
gyrA	8520	c.1219C>T	synonymous_variant	0.97	moxifloxacin
gyrA	8531	c.1230G>C	synonymous_variant	0.97	levofloxacin
gyrA	8531	c.1230G>C	synonymous_variant	0.97	moxifloxacin
gyrA	8543	c.1242C>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8543	c.1242C>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8546	c.1245T>C	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8552	c.1251_1254delCCGGinsGC	frameshift_variant&synonymous_variant	0.97	levofloxacin
gyrA	8552	c.1251_1254delCCGGinsGC	frameshift_variant&synonymous_variant	0.97	moxifloxacin
gyrA	8559	c.1258_1260delGGAinsAGGGC	frameshift_variant&missense_variant	1.0	levofloxacin
gyrA	8559	c.1258_1260delGGAinsAGGGC	frameshift_variant&missense_variant	1.0	moxifloxacin
gyrA	8588	p.Glu429Asp	missense_variant	1.0	levofloxacin
gyrA	8588	p.Glu429Asp	missense_variant	1.0	moxifloxacin
gyrA	8603	c.1302A>C	synonymous_variant	1.0	levofloxacin
gyrA	8603	c.1302A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8619	c.1318T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8619	c.1318T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8624	c.1323G>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8627	c.1326C>G	synonymous_variant	1.0	levofloxacin
gyrA	8627	c.1326C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8636	c.1335A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8636	c.1335A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8645	c.1344C>G	synonymous_variant	0.97	levofloxacin
gyrA	8645	c.1344C>G	synonymous_variant	0.97	moxifloxacin
gyrA	8651	c.1350C>G	synonymous_variant	1.0	levofloxacin
gyrA	8651	c.1350C>G	synonymous_variant	1.0	moxifloxacin
gyrA	8655	p.Ile452Val	missense_variant	1.0	levofloxacin
gyrA	8655	p.Ile452Val	missense_variant	1.0	moxifloxacin
gyrA	8672	c.1371A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8672	c.1371A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8711	c.1410A>C	synonymous_variant	0.98	levofloxacin
gyrA	8711	c.1410A>C	synonymous_variant	0.98	moxifloxacin
gyrA	8714	c.1413A>G	synonymous_variant	0.98	levofloxacin
gyrA	8714	c.1413A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8729	c.1428T>C	synonymous_variant	0.98	levofloxacin
gyrA	8729	c.1428T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8747	c.1446A>G	synonymous_variant	0.98	levofloxacin
gyrA	8747	c.1446A>G	synonymous_variant	0.98	moxifloxacin
gyrA	8751	p.Ala484Lys	missense_variant	0.97	levofloxacin
gyrA	8751	p.Ala484Lys	missense_variant	0.97	moxifloxacin
gyrA	8756	c.1455A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8756	c.1455A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8762	c.1461G>C	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	8762	c.1461G>C	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	8767	p.Arg489Lys	missense_variant	0.98	levofloxacin	Uncertain significance
gyrA	8767	p.Arg489Lys	missense_variant	0.98	moxifloxacin	Uncertain significance
gyrA	8783	c.1482G>T	synonymous_variant	0.98	levofloxacin
gyrA	8783	c.1482G>T	synonymous_variant	0.98	moxifloxacin
gyrA	8786	c.1485T>C	synonymous_variant	0.98	levofloxacin
gyrA	8786	c.1485T>C	synonymous_variant	0.98	moxifloxacin
gyrA	8792	c.1491G>C	synonymous_variant	0.98	levofloxacin
gyrA	8792	c.1491G>C	synonymous_variant	0.98	moxifloxacin
gyrA	8796	c.1495_1497delATCinsGG	frameshift_variant&missense_variant	0.98	levofloxacin
gyrA	8796	c.1495_1497delATCinsGG	frameshift_variant&missense_variant	0.98	moxifloxacin
gyrA	8801	c.1500G>C	synonymous_variant	1.0	levofloxacin
gyrA	8801	c.1500G>C	synonymous_variant	1.0	moxifloxacin
gyrA	8810	c.1509A>C	synonymous_variant	1.0	levofloxacin
gyrA	8810	c.1509A>C	synonymous_variant	1.0	moxifloxacin
gyrA	8813	p.Asp504Glu	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	8813	p.Asp504Glu	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	8828	c.1527T>C	synonymous_variant	1.0	levofloxacin
gyrA	8828	c.1527T>C	synonymous_variant	1.0	moxifloxacin
gyrA	8829	c.1528T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	8829	c.1528T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	8852	c.1551T>C	synonymous_variant	0.97	levofloxacin
gyrA	8852	c.1551T>C	synonymous_variant	0.97	moxifloxacin
gyrA	8858	c.1557T>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8858	c.1557T>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8867	c.1566A>G	synonymous_variant	0.97	levofloxacin	Not assoc w R - Interim
gyrA	8867	c.1566A>G	synonymous_variant	0.97	moxifloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8870	c.1569G>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	8873	c.1572A>C	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	8897	c.1596T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrA	8897	c.1596T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	8900	c.1599G>C	synonymous_variant	0.95	levofloxacin
gyrA	8900	c.1599G>C	synonymous_variant	0.95	moxifloxacin
gyrA	8903	c.1602T>C	synonymous_variant	0.95	levofloxacin	Not assoc w R - Interim
gyrA	8903	c.1602T>C	synonymous_variant	0.95	moxifloxacin	Not assoc w R - Interim
gyrA	8939	c.1638T>C	synonymous_variant	0.94	levofloxacin
gyrA	8939	c.1638T>C	synonymous_variant	0.94	moxifloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.94	levofloxacin
gyrA	8942	c.1641G>C	synonymous_variant	0.94	moxifloxacin
gyrA	8946	c.1645_1647delTTGinsCC	frameshift_variant&missense_variant	0.94	levofloxacin
gyrA	8946	c.1645_1647delTTGinsCC	frameshift_variant&missense_variant	0.94	moxifloxacin
gyrA	8967	p.Ala556Asn	missense_variant	0.93	levofloxacin
gyrA	8967	p.Ala556Asn	missense_variant	0.93	moxifloxacin
gyrA	8981	c.1680G>C	synonymous_variant	0.93	levofloxacin	Not assoc w R - Interim
gyrA	8981	c.1680G>C	synonymous_variant	0.93	moxifloxacin	Not assoc w R - Interim
gyrA	8987	c.1686C>G	synonymous_variant	0.96	levofloxacin
gyrA	8987	c.1686C>G	synonymous_variant	0.96	moxifloxacin
gyrA	8990	c.1689C>G	synonymous_variant	0.95	levofloxacin
gyrA	8990	c.1689C>G	synonymous_variant	0.95	moxifloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.95	levofloxacin
gyrA	8996	c.1695T>C	synonymous_variant	0.95	moxifloxacin
gyrA	8998	p.Leu566Trp	missense_variant	0.95	levofloxacin	Uncertain significance
gyrA	8998	p.Leu566Trp	missense_variant	0.95	moxifloxacin	Uncertain significance
gyrA	9017	c.1716C>G	synonymous_variant	0.94	levofloxacin	Not assoc w R - Interim
gyrA	9017	c.1716C>G	synonymous_variant	0.94	moxifloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9023	c.1722A>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9029	c.1728T>G	synonymous_variant	1.0	levofloxacin
gyrA	9029	c.1728T>G	synonymous_variant	1.0	moxifloxacin
gyrA	9032	c.1731T>C	synonymous_variant	1.0	levofloxacin
gyrA	9032	c.1731T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9182	c.1881T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9182	c.1881T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9191	c.1890G>T	synonymous_variant	1.0	levofloxacin
gyrA	9191	c.1890G>T	synonymous_variant	1.0	moxifloxacin
gyrA	9200	c.1899A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9200	c.1899A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9206	c.1905C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9206	c.1905C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9207	p.Lys636Arg	missense_variant	1.0	levofloxacin
gyrA	9207	p.Lys636Arg	missense_variant	1.0	moxifloxacin
gyrA	9227	c.1926C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9227	c.1926C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9230	c.1929T>C	synonymous_variant	1.0	levofloxacin
gyrA	9230	c.1929T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9236	c.1935G>C	synonymous_variant	1.0	levofloxacin
gyrA	9236	c.1935G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9242	c.1941A>C	synonymous_variant	1.0	levofloxacin
gyrA	9242	c.1941A>C	synonymous_variant	1.0	moxifloxacin
gyrA	9252	p.Val651Ile	missense_variant	1.0	levofloxacin	Uncertain significance
gyrA	9252	p.Val651Ile	missense_variant	1.0	moxifloxacin	Uncertain significance
gyrA	9263	c.1962C>T	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9263	c.1962C>T	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9267	p.Asn656Gly	missense_variant	1.0	levofloxacin
gyrA	9267	p.Asn656Gly	missense_variant	1.0	moxifloxacin
gyrA	9275	c.1974G>A	synonymous_variant	1.0	levofloxacin
gyrA	9275	c.1974G>A	synonymous_variant	1.0	moxifloxacin
gyrA	9284	c.1983T>G	synonymous_variant	1.0	levofloxacin
gyrA	9284	c.1983T>G	synonymous_variant	1.0	moxifloxacin
gyrA	9287	c.1986G>T	synonymous_variant	1.0	levofloxacin
gyrA	9287	c.1986G>T	synonymous_variant	1.0	moxifloxacin
gyrA	9296	c.1995T>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9296	c.1995T>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9304	p.Gly668Asp	missense_variant	1.0	levofloxacin	Not assoc w R
gyrA	9304	p.Gly668Asp	missense_variant	1.0	moxifloxacin	Not assoc w R
gyrA	9311	c.2010C>T	synonymous_variant	1.0	levofloxacin
gyrA	9311	c.2010C>T	synonymous_variant	1.0	moxifloxacin
gyrA	9323	c.2022C>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9323	c.2022C>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9335	c.2034G>C	synonymous_variant	1.0	levofloxacin
gyrA	9335	c.2034G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9345	c.2044A>C	synonymous_variant	1.0	levofloxacin
gyrA	9345	c.2044A>C	synonymous_variant	1.0	moxifloxacin
gyrA	9356	c.2055G>A	synonymous_variant	0.98	levofloxacin
gyrA	9356	c.2055G>A	synonymous_variant	0.98	moxifloxacin
gyrA	9374	c.2073G>C	synonymous_variant	1.0	levofloxacin
gyrA	9374	c.2073G>C	synonymous_variant	1.0	moxifloxacin
gyrA	9377	c.2076A>G	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9377	c.2076A>G	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9383	c.2082T>C	synonymous_variant	1.0	levofloxacin
gyrA	9383	c.2082T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9386	c.2085T>G	synonymous_variant	1.0	levofloxacin
gyrA	9386	c.2085T>G	synonymous_variant	1.0	moxifloxacin
gyrA	9395	c.2094G>C	synonymous_variant	1.0	levofloxacin	Not assoc w R - Interim
gyrA	9395	c.2094G>C	synonymous_variant	1.0	moxifloxacin	Not assoc w R - Interim
gyrA	9398	c.2097T>C	synonymous_variant	1.0	levofloxacin
gyrA	9398	c.2097T>C	synonymous_variant	1.0	moxifloxacin
gyrA	9419	c.2118T>C	synonymous_variant	0.98	levofloxacin
gyrA	9419	c.2118T>C	synonymous_variant	0.98	moxifloxacin
gyrA	9420	p.Ile707Ala	missense_variant	0.98	levofloxacin
gyrA	9420	p.Ile707Ala	missense_variant	0.98	moxifloxacin
gyrA	9455	c.2154T>C	synonymous_variant	0.98	levofloxacin
gyrA	9455	c.2154T>C	synonymous_variant	0.98	moxifloxacin
gyrA	9464	c.2163C>A	synonymous_variant	0.98	levofloxacin	Not assoc w R - Interim
gyrA	9464	c.2163C>A	synonymous_variant	0.98	moxifloxacin	Not assoc w R - Interim
gyrA	9476	c.2175G>C	synonymous_variant	0.97	levofloxacin
gyrA	9476	c.2175G>C	synonymous_variant	0.97	moxifloxacin
gyrA	9479	c.2178G>C	synonymous_variant	0.97	levofloxacin
gyrA	9479	c.2178G>C	synonymous_variant	0.97	moxifloxacin
gyrA	9485	c.2184A>C	synonymous_variant	0.97	levofloxacin
gyrA	9485	c.2184A>C	synonymous_variant	0.97	moxifloxacin
gyrA	9488	c.2187G>T	synonymous_variant	0.97	levofloxacin
gyrA	9488	c.2187G>T	synonymous_variant	0.97	moxifloxacin
gyrA	9494	c.2193T>C	synonymous_variant	0.96	levofloxacin
gyrA	9494	c.2193T>C	synonymous_variant	0.96	moxifloxacin
gyrA	9497	c.2196G>C	synonymous_variant	0.96	levofloxacin
gyrA	9497	c.2196G>C	synonymous_variant	0.96	moxifloxacin
gyrA	9500	c.2199A>G	synonymous_variant	0.96	levofloxacin	Not assoc w R - Interim
gyrA	9500	c.2199A>G	synonymous_variant	0.96	moxifloxacin	Not assoc w R - Interim
gyrA	9503	c.2202T>C	synonymous_variant	0.96	levofloxacin
gyrA	9503	c.2202T>C	synonymous_variant	0.96	moxifloxacin
gyrA	9509	c.2208G>C	synonymous_variant	0.96	levofloxacin
gyrA	9509	c.2208G>C	synonymous_variant	0.96	moxifloxacin
gyrA	9518	c.2217A>G	synonymous_variant	0.96	levofloxacin
gyrA	9518	c.2217A>G	synonymous_variant	0.96	moxifloxacin
gyrA	9527	c.2226A>G	synonymous_variant	0.96	levofloxacin
gyrA	9527	c.2226A>G	synonymous_variant	0.96	moxifloxacin
gyrA	9542	c.2241T>C	synonymous_variant	0.93	levofloxacin
gyrA	9542	c.2241T>C	synonymous_variant	0.93	moxifloxacin
fgd1	490851	c.69A>G	synonymous_variant	0.86	clofazimine
					pretomanid
					delamanid
fgd1	490853	p.Ala24Gly	missense_variant	0.86	clofazimine
					pretomanid
					delamanid
fgd1	490859	p.Ala26Glu	missense_variant	0.81	clofazimine
					pretomanid
					delamanid
fgd1	490869	c.87C>G	synonymous_variant	0.84	clofazimine
					pretomanid
					delamanid
fgd1	490890	c.108C>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	490899	c.117C>T	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490902	c.120T>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490905	c.123T>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490911	c.129T>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	490917	c.135C>T	synonymous_variant	0.98	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fgd1	490921	p.Gln47Glu	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490932	c.150T>C	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490935	c.153C>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490962	c.180T>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	490968	c.186C>T	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	490971	c.189A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	490974	c.192T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	490980	p.Asn66Lys	missense_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491010	c.228C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491013	c.231C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491016	c.234C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491037	c.255C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491043	c.261T>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491049	c.267T>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491064	c.282A>G	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fgd1	491073	c.291C>T	synonymous_variant	0.97	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fgd1	491077	p.Asn99Asp	missense_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491082	c.300T>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491091	c.309T>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491094	c.312C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491106	c.324T>A	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fgd1	491115	c.333G>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491121	c.339A>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491133	c.351A>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491144	p.Ala121Asp	missense_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491181	c.399T>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fgd1	491187	c.405G>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fgd1	491461	p.Lys227Arg	missense_variant	0.82	clofazimine
					pretomanid
					delamanid
fgd1	491472	c.690A>G	synonymous_variant	0.88	clofazimine
					pretomanid
					delamanid
fgd1	491487	c.705C>T	synonymous_variant	0.88	clofazimine
					pretomanid
					delamanid
fgd1	491496	c.714C>T	synonymous_variant	0.88	clofazimine
					pretomanid
					delamanid
fgd1	491499	c.717G>C	synonymous_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491502	p.Glu240Asp	missense_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491508	c.726A>G	synonymous_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491509	c.727T>C	synonymous_variant	0.83	clofazimine
					pretomanid
					delamanid
fgd1	491521	c.739C>A	synonymous_variant	0.84	clofazimine
					pretomanid
					delamanid
fgd1	491526	c.744T>C	synonymous_variant	0.85	clofazimine
					pretomanid
					delamanid
fgd1	491542	c.760T>C	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fgd1	491547	c.765A>C	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fgd1	491550	c.768T>C	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fgd1	491601	c.819T>C	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fgd1	491610	c.828A>G	synonymous_variant	0.93	clofazimine
					pretomanid
					delamanid
fgd1	491616	c.834A>G	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491620	p.Ile280Val	missense_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491643	c.861G>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491646	c.864G>A	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fgd1	491649	c.867C>T	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	491655	c.873C>T	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	491658	c.876A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fgd1	491673	c.891A>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491676	c.894T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491679	c.897A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491687	p.Thr302Lys	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fgd1	491697	c.915G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
mshA	575652	p.Arg102Pro	missense_variant	0.82	ethionamide
mshA	575652	p.Arg102Pro	missense_variant	0.82	isoniazid
mshA	575659	c.312A>G	synonymous_variant	0.87	ethionamide
mshA	575659	c.312A>G	synonymous_variant	0.87	isoniazid
mshA	575665	c.318G>A	synonymous_variant	0.89	ethionamide
mshA	575665	c.318G>A	synonymous_variant	0.89	isoniazid
mshA	575671	c.324G>C	synonymous_variant	0.91	ethionamide
mshA	575671	c.324G>C	synonymous_variant	0.91	isoniazid
mshA	575683	c.336G>C	synonymous_variant	0.93	ethionamide
mshA	575683	c.336G>C	synonymous_variant	0.93	isoniazid
mshA	575689	c.342G>C	synonymous_variant	0.94	ethionamide
mshA	575689	c.342G>C	synonymous_variant	0.94	isoniazid
mshA	575695	c.348C>G	synonymous_variant	0.94	ethionamide
mshA	575695	c.348C>G	synonymous_variant	0.94	isoniazid	Not assoc w R - Interim
mshA	575704	c.357T>C	synonymous_variant	0.95	ethionamide
mshA	575704	c.357T>C	synonymous_variant	0.95	isoniazid
mshA	575734	c.387T>G	synonymous_variant	0.96	ethionamide
mshA	575734	c.387T>G	synonymous_variant	0.96	isoniazid
mshA	575737	c.390T>C	synonymous_variant	0.96	ethionamide
mshA	575737	c.390T>C	synonymous_variant	0.96	isoniazid
mshA	575744	p.Ala133Thr	missense_variant	0.96	ethionamide
mshA	575744	p.Ala133Thr	missense_variant	0.96	isoniazid	Uncertain significance
mshA	575749	c.402C>G	synonymous_variant	0.95	ethionamide
mshA	575749	c.402C>G	synonymous_variant	0.95	isoniazid
mshA	575752	c.405G>C	synonymous_variant	0.98	ethionamide
mshA	575752	c.405G>C	synonymous_variant	0.98	isoniazid
mshA	575770	c.423G>C	synonymous_variant	1.0	ethionamide
mshA	575770	c.423G>C	synonymous_variant	1.0	isoniazid
mshA	575771	p.Val142Thr	missense_variant	1.0	ethionamide
mshA	575771	p.Val142Thr	missense_variant	1.0	isoniazid
mshA	575782	c.435G>C	synonymous_variant	1.0	ethionamide
mshA	575782	c.435G>C	synonymous_variant	1.0	isoniazid
mshA	575785	c.438T>C	synonymous_variant	1.0	ethionamide
mshA	575785	c.438T>C	synonymous_variant	1.0	isoniazid
mshA	575821	c.474G>C	synonymous_variant	0.98	ethionamide
mshA	575821	c.474G>C	synonymous_variant	0.98	isoniazid
mshA	575842	c.495G>A	synonymous_variant	0.96	ethionamide
mshA	575842	c.495G>A	synonymous_variant	0.96	isoniazid
mshA	575845	c.498C>G	synonymous_variant	0.96	ethionamide
mshA	575845	c.498C>G	synonymous_variant	0.96	isoniazid
mshA	575864	c.517T>C	synonymous_variant	0.96	ethionamide
mshA	575864	c.517T>C	synonymous_variant	0.96	isoniazid
mshA	575878	c.531A>G	synonymous_variant	0.95	ethionamide
mshA	575878	c.531A>G	synonymous_variant	0.95	isoniazid
mshA	575896	c.549G>C	synonymous_variant	0.94	ethionamide
mshA	575896	c.549G>C	synonymous_variant	0.94	isoniazid
mshA	575905	c.558G>C	synonymous_variant	0.93	ethionamide
mshA	575905	c.558G>C	synonymous_variant	0.93	isoniazid
mshA	575908	c.561A>G	synonymous_variant	0.92	ethionamide
mshA	575908	c.561A>G	synonymous_variant	0.92	isoniazid
mshA	575911	c.564G>T	synonymous_variant	0.92	ethionamide
mshA	575911	c.564G>T	synonymous_variant	0.92	isoniazid
mshA	575917	p.Asp190Glu	missense_variant	0.92	ethionamide
mshA	575917	p.Asp190Glu	missense_variant	0.92	isoniazid
mshA	575920	c.573C>T	synonymous_variant	0.92	ethionamide	Not assoc w R - Interim
mshA	575920	c.573C>T	synonymous_variant	0.92	isoniazid	Not assoc w R - Interim
mshA	575925	p.Gly193Ala	missense_variant	0.92	ethionamide
mshA	575925	p.Gly193Ala	missense_variant	0.92	isoniazid
mshA	575929	c.582C>G	synonymous_variant	0.92	ethionamide
mshA	575929	c.582C>G	synonymous_variant	0.92	isoniazid
mshA	575932	c.585G>A	synonymous_variant	0.92	ethionamide
mshA	575932	c.585G>A	synonymous_variant	0.92	isoniazid
mshA	575944	c.597T>C	synonymous_variant	0.92	ethionamide
mshA	575944	c.597T>C	synonymous_variant	0.92	isoniazid
mshA	575945	p.Thr200Ala	missense_variant	0.92	ethionamide
mshA	575945	p.Thr200Ala	missense_variant	0.92	isoniazid
mshA	575953	c.606G>C	synonymous_variant	0.91	ethionamide
mshA	575953	c.606G>C	synonymous_variant	0.91	isoniazid
mshA	575956	c.609G>A	synonymous_variant	0.91	ethionamide
mshA	575956	c.609G>A	synonymous_variant	0.91	isoniazid
ccsA	619615	c.-276C>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619629	c.-262G>C	upstream_gene_variant	0.85	capreomycin
					amikacin
					kanamycin
ccsA	619648	c.-243C>G	upstream_gene_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	619654	c.-237A>G	upstream_gene_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	619657	c.-234C>G	upstream_gene_variant	0.89	capreomycin
					amikacin
					kanamycin
ccsA	619669	c.-222G>T	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619672	c.-219A>G	upstream_gene_variant	0.87	capreomycin
					amikacin
					kanamycin
ccsA	619696	c.-195C>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619697	c.-194_-192delAGGinsCA	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619702	c.-189C>A	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619706	c.-185_-183delGTGinsAC	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619713	c.-178C>T	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619723	c.-168G>C	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619727	c.-164delAinsGC	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619732	c.-158delG	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619746	c.-145A>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619762	c.-129C>G	upstream_gene_variant	0.87	capreomycin
					amikacin
					kanamycin
ccsA	619763	c.-128C>T	upstream_gene_variant	0.83	capreomycin
					amikacin
					kanamycin
ccsA	619766	c.-125_-123delACGinsGC	upstream_gene_variant	0.83	capreomycin
					amikacin
					kanamycin
ccsA	619774	c.-117C>G	upstream_gene_variant	0.91	capreomycin
					amikacin
					kanamycin
ccsA	619783	c.-108C>G	upstream_gene_variant	0.82	capreomycin
					amikacin
					kanamycin
ccsA	619794	c.-97C>A	upstream_gene_variant	0.8	capreomycin
					amikacin
					kanamycin
ccsA	620238	c.348G>C	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620247	p.Leu119Phe	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620249	p.Ser120Cys	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620253	c.363G>C	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620256	c.366C>G	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620257	p.Ile123Val	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620264	p.Gly125Ala	missense_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620268	c.378G>C	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620271	c.381C>G	synonymous_variant	0.88	capreomycin
					amikacin
					kanamycin
ccsA	620283	c.393T>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620284	p.Ala132Pro	missense_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620288	p.Arg133Gln	missense_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620295	c.405G>C	synonymous_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620296	p.Pro136Ala	missense_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620307	c.417C>G	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620311	p.Leu141Val	missense_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620316	c.426G>C	synonymous_variant	0.96	capreomycin
					amikacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
ccsA	620337	c.447C>G	synonymous_variant	0.97	capreomycin
					amikacin
					kanamycin
ccsA	620340	c.450C>G	synonymous_variant	0.96	capreomycin
					amikacin
					kanamycin
ccsA	620346	c.456C>G	synonymous_variant	0.96	capreomycin
					amikacin
					kanamycin
ccsA	620349	c.459A>C	synonymous_variant	0.96	capreomycin
					amikacin
					kanamycin
ccsA	620362	p.Ala158Thr	missense_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620367	c.477T>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620388	c.498A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620409	c.519C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620412	c.522T>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620415	c.525T>C	synonymous_variant	1.0	capreomycin	Not assoc w R - Interim
					amikacin	Not assoc w R - Interim
					kanamycin	Not assoc w R - Interim
ccsA	620436	c.546T>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620439	c.549T>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620442	c.552G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620445	c.555A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620625	c.735A>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620631	c.741T>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620634	c.744C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620649	c.759A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620652	c.762C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620670	c.780C>T	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620694	c.804C>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620698	p.Val270Ile	missense_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620709	c.819G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620710	c.820_822delGTGinsAC	frameshift_variant&missense_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620721	c.831G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620730	c.840C>T	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620733	c.843G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620736	c.846G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620739	c.849A>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620748	c.858T>G	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620754	c.864G>C	synonymous_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620758	p.Arg290Lys	missense_variant	1.0	capreomycin
					amikacin
					kanamycin
ccsA	620778	c.888T>C	synonymous_variant	0.95	capreomycin
					amikacin
					kanamycin
ccsA	620784	c.894C>A	synonymous_variant	0.94	capreomycin
					amikacin
					kanamycin
ccsA	620793	c.903G>C	synonymous_variant	0.93	capreomycin
					amikacin
					kanamycin
ccsA	620796	c.906C>G	synonymous_variant	0.92	capreomycin
					amikacin
					kanamycin
ccsA	620802	c.912C>G	synonymous_variant	0.91	capreomycin
					amikacin
					kanamycin
Rv0565c	657596	c.-126G>C	upstream_gene_variant	1.0	ethionamide
Rv0565c	657620	c.-150C>T	upstream_gene_variant	1.0	ethionamide
Rv0565c	657635	c.-167_-165delAGCinsTCG	upstream_gene_variant	1.0	ethionamide
Rv0565c	657640	c.-170A>T	upstream_gene_variant	1.0	ethionamide
Rv0565c	657641	c.-171C>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657647	c.-177C>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657670	c.-200A>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657671	c.-201A>G	upstream_gene_variant	1.0	ethionamide
Rv0565c	657678	c.-209_-208delAAinsGG	upstream_gene_variant	1.0	ethionamide
Rv0565c	657689	c.-220_-219delCAinsAG	upstream_gene_variant	0.98	ethionamide
Rv0565c	657734	c.-264T>C	upstream_gene_variant	1.0	ethionamide
nusG	734421	c.168A>C	synonymous_variant	1.0	rifampicin
nusG	734424	c.171G>C	synonymous_variant	1.0	rifampicin
nusG	734439	c.186C>G	synonymous_variant	1.0	rifampicin
nusG	734442	c.189G>A	synonymous_variant	1.0	rifampicin
nusG	734451	c.198G>C	synonymous_variant	1.0	rifampicin
nusG	734454	c.201A>G	synonymous_variant	1.0	rifampicin
nusG	734460	c.207G>C	synonymous_variant	1.0	rifampicin
nusG	734472	c.219T>C	synonymous_variant	1.0	rifampicin
nusG	734475	c.222T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
nusG	734499	c.246G>C	synonymous_variant	1.0	rifampicin
nusG	734505	c.252G>C	synonymous_variant	0.97	rifampicin
nusG	734532	c.279A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
nusG	734541	c.288A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
nusG	734559	c.306T>C	synonymous_variant	0.96	rifampicin
nusG	734580	c.327T>C	synonymous_variant	0.83	rifampicin	Not assoc w R - Interim
nusG	734814	c.561G>C	synonymous_variant	0.8	rifampicin
nusG	734820	c.567A>G	synonymous_variant	0.8	rifampicin	Not assoc w R - Interim
nusG	734826	c.573A>C	synonymous_variant	0.8	rifampicin
nusG	734847	c.594T>C	synonymous_variant	0.9	rifampicin
nusG	734853	c.600A>G	synonymous_variant	0.9	rifampicin
nusG	734854	c.601T>C	synonymous_variant	0.9	rifampicin
nusG	734862	c.609C>G	synonymous_variant	0.9	rifampicin
nusG	734863	p.Thr204Ser	missense_variant	0.9	rifampicin
rpoB	760139	c.333A>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760140	p.Pro112Ser	missense_variant	0.92	rifampicin
rpoB	760148	c.342C>T	synonymous_variant	0.94	rifampicin
rpoB	760184	c.378A>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	760196	c.390C>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	760208	p.Ile134Met	missense_variant	0.9	rifampicin
rpoB	760212	p.Asn136Ala	missense_variant	0.9	rifampicin
rpoB	760215	c.409_411delAACinsGG	frameshift_variant&missense_variant	0.9	rifampicin
rpoB	760219	p.Thr138Ser	missense_variant	0.9	rifampicin
rpoB	760223	c.417T>C	synonymous_variant	0.91	rifampicin
rpoB	760235	c.429T>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760244	c.438G>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	760283	c.477G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760298	c.492G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760310	c.504G>C	synonymous_variant	0.97	rifampicin
rpoB	760316	c.510C>G	synonymous_variant	0.97	rifampicin
rpoB	760317	c.511_513delAGCinsTCG	synonymous_variant	0.97	rifampicin
rpoB	760328	c.522G>T	synonymous_variant	0.97	rifampicin
rpoB	760331	c.525G>C	synonymous_variant	1.0	rifampicin
rpoB	760340	c.534G>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760361	c.555T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760406	c.600G>C	synonymous_variant	0.96	rifampicin
rpoB	760407	p.Ser201Gly	missense_variant	0.96	rifampicin	Uncertain significance
rpoB	760424	c.618C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760430	c.624T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	760454	c.648C>G	synonymous_variant	0.96	rifampicin
rpoB	760475	c.669A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760478	c.672C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760481	c.675G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760484	c.678A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760487	c.681G>C	synonymous_variant	0.96	rifampicin
rpoB	760502	c.696C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	760522	p.Ser239Asn	missense_variant	0.98	rifampicin	Uncertain significance
rpoB	760532	c.726T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760533	p.Val243Thr	missense_variant	0.97	rifampicin
rpoB	760547	c.741G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760551	c.745_746delTCinsAG	synonymous_variant	0.97	rifampicin
rpoB	760563	c.757delCinsAT	frameshift_variant&synonymous_variant	1.0	rifampicin
rpoB	760566	p.Ser254Ala	missense_variant	1.0	rifampicin
rpoB	760567	c.762delG	frameshift_variant	1.0	rifampicin
rpoB	760591	p.Val262Ala	missense_variant	1.0	rifampicin
rpoB	760608	c.802C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760611	c.805T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760634	c.828T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760646	c.840C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760655	c.849A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760661	c.855A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760670	c.864G>C	synonymous_variant	1.0	rifampicin
rpoB	760674	c.868T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760679	c.873A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760683	c.877T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760724	c.918T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	760916	c.1110C>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	760925	c.1119T>C	synonymous_variant	0.95	rifampicin
rpoB	760946	c.1140A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	760958	c.1152G>C	synonymous_variant	0.94	rifampicin
rpoB	760965	p.Met387Leu	missense_variant	0.92	rifampicin	Uncertain significance
rpoB	760970	c.1164G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760973	c.1167G>C	synonymous_variant	0.92	rifampicin
rpoB	760982	c.1176G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760988	c.1182C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	760991	c.1185G>C	synonymous_variant	0.93	rifampicin
rpoB	760997	c.1191G>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761015	c.1209G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761027	c.1221A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761036	c.1230G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761037	c.1231T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761051	c.1245G>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761054	c.1248G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761057	c.1251G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761060	c.1254C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761063	c.1257C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761087	c.1281C>G	synonymous_variant	0.93	rifampicin
rpoB	761088	c.1282_1284delAGCinsTCG	synonymous_variant	0.93	rifampicin
rpoB	761097	c.1291_1293delAGCinsTCG	synonymous_variant	0.93	rifampicin
rpoB	761102	c.1296A>G	synonymous_variant	0.93	rifampicin
rpoB	761147	c.1341C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761150	c.1344A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761153	c.1347G>C	synonymous_variant	1.0	rifampicin
rpoB	761165	c.1359G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	761168	c.1362C>G	synonymous_variant	0.98	rifampicin
rpoB	761174	c.1368T>C	synonymous_variant	1.0	rifampicin
rpoB	761180	c.1374A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761189	c.1383T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761195	c.1389G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761198	c.1392G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761204	c.1398C>G	synonymous_variant	0.97	rifampicin
rpoB	761217	c.1411_1413delCCGinsGC	frameshift_variant&missense_variant	0.94	rifampicin
rpoB	761220	c.1414_1416delTCGinsAGC	synonymous_variant	0.94	rifampicin
rpoB	761249	c.1443A>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761255	c.1449T>C	synonymous_variant	0.93	rifampicin
rpoB	761261	c.1455G>T	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761264	c.1458C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761300	c.1494G>C	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	761303	c.1497G>A	synonymous_variant	0.89	rifampicin
rpoB	761327	c.1521A>G	synonymous_variant	0.89	rifampicin	Not assoc w R - Interim
rpoB	761345	c.1539G>C	synonymous_variant	0.88	rifampicin
rpoB	761357	c.1551G>A	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoB	761362	p.Ser519Thr	missense_variant	0.95	rifampicin
rpoB	761366	c.1560C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761375	c.1569G>C	synonymous_variant	0.95	rifampicin
rpoB	761403	p.His533Tyr	missense_variant	1.0	rifampicin
rpoB	761537	c.1731C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761555	c.1749G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761558	c.1752C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoB	761561	c.1755C>G	synonymous_variant	0.96	rifampicin
rpoB	761570	c.1764T>C	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoB	761573	c.1767C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761579	c.1773G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	761600	c.1794T>C	synonymous_variant	1.0	rifampicin
rpoB	761606	c.1800C>G	synonymous_variant	0.97	rifampicin
rpoB	761612	c.1806G>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	761615	c.1809A>C	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761627	c.1821C>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761636	c.1830G>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761645	c.1839C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoB	761648	c.1842T>C	synonymous_variant	0.94	rifampicin
rpoB	761666	c.1860G>C	synonymous_variant	0.95	rifampicin
rpoB	761669	c.1863C>T	synonymous_variant	0.94	rifampicin
rpoB	761675	c.1869G>C	synonymous_variant	0.95	rifampicin
rpoB	761682	c.1876C>T	synonymous_variant	0.94	rifampicin
rpoB	761687	c.1881C>T	synonymous_variant	0.94	rifampicin
rpoB	761690	c.1884G>C	synonymous_variant	0.94	rifampicin
rpoB	761705	c.1899C>T	synonymous_variant	0.93	rifampicin
rpoB	761723	p.Glu639Asp	missense_variant	0.9	rifampicin	Not assoc w R
rpoB	761724	c.1918_1920delGAAinsAC	frameshift_variant&missense_variant	0.89	rifampicin
rpoB	761727	p.Ser641Ala	missense_variant	0.89	rifampicin
rpoB	761732	c.1926C>G	synonymous_variant	0.9	rifampicin	Not assoc w R - Interim
rpoB	761735	c.1929C>G	synonymous_variant	0.91	rifampicin
rpoB	761747	c.1941G>C	synonymous_variant	0.93	rifampicin
rpoB	761750	c.1944G>C	synonymous_variant	0.91	rifampicin
rpoB	761765	c.1959T>C	synonymous_variant	0.97	rifampicin
rpoB	761772	p.His656Ala	missense_variant	0.97	rifampicin
rpoB	761778	p.Asn658Asp	missense_variant	0.97	rifampicin
rpoB	761791	p.Arg662Gln	missense_variant	0.95	rifampicin
rpoB	761813	c.2007T>C	synonymous_variant	0.95	rifampicin
rpoB	761834	c.2028T>C	synonymous_variant	0.91	rifampicin
rpoB	761847	p.Cys681Arg	missense_variant	0.92	rifampicin	Uncertain significance
rpoB	761852	c.2046C>G	synonymous_variant	0.92	rifampicin
rpoB	761858	c.2052G>C	synonymous_variant	0.92	rifampicin
rpoB	761864	c.2058G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoB	761873	c.2067A>G	synonymous_variant	0.92	rifampicin
rpoB	761876	c.2070C>G	synonymous_variant	0.92	rifampicin
rpoB	761885	c.2079T>C	synonymous_variant	0.92	rifampicin
rpoB	761891	c.2085G>C	synonymous_variant	0.92	rifampicin
rpoB	761903	c.2097T>G	synonymous_variant	0.93	rifampicin
rpoB	761906	c.2100C>G	synonymous_variant	0.93	rifampicin
rpoB	761909	c.2103T>C	synonymous_variant	0.93	rifampicin
rpoB	761912	c.2106T>C	synonymous_variant	0.93	rifampicin
rpoB	761915	p.Asp703Glu	missense_variant	0.93	rifampicin
rpoB	761916	p.Asp704Asn	missense_variant	0.93	rifampicin
rpoB	761948	c.2142G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761951	c.2145G>C	synonymous_variant	0.96	rifampicin
rpoB	761954	c.2148C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	761999	c.2193G>C	synonymous_variant	1.0	rifampicin
rpoB	762008	c.2202C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762014	c.2208C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762017	c.2211A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762053	c.2247T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762062	c.2256T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762065	c.2259T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762083	c.2277T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762086	c.2280G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762101	c.2295C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762114	p.Ile770Val	missense_variant	1.0	rifampicin	Uncertain significance
rpoB	762122	c.2316C>T	synonymous_variant	1.0	rifampicin
rpoB	762131	c.2325C>G	synonymous_variant	1.0	rifampicin
rpoB	762140	c.2334G>C	synonymous_variant	1.0	rifampicin
rpoB	762143	c.2337T>C	synonymous_variant	1.0	rifampicin
rpoB	762149	c.2343G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762158	c.2352G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762167	c.2361T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762176	c.2370T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762185	c.2379G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762233	c.2427G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762257	c.2451C>G	synonymous_variant	1.0	rifampicin
rpoB	762275	c.2469C>G	synonymous_variant	1.0	rifampicin
rpoB	762284	c.2478G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762293	c.2487T>G	synonymous_variant	1.0	rifampicin
rpoB	762314	c.2508C>T	synonymous_variant	1.0	rifampicin
rpoB	762317	c.2511A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762338	c.2532T>C	synonymous_variant	1.0	rifampicin
rpoB	762341	c.2535G>C	synonymous_variant	1.0	rifampicin
rpoB	762347	c.2541T>C	synonymous_variant	1.0	rifampicin
rpoB	762362	p.Glu852Asp	missense_variant	1.0	rifampicin
rpoB	762369	c.2563T>C	synonymous_variant	1.0	rifampicin
rpoC	762374	c.-996G>C	upstream_gene_variant	1.0	rifampicin
rpoC	762380	c.-990T>C	upstream_gene_variant	1.0	rifampicin
rpoC	762395	c.-975G>C	upstream_gene_variant	1.0	rifampicin
rpoC	762398	c.-972T>C	upstream_gene_variant	0.98	rifampicin
rpoC	762401	c.-969G>C	upstream_gene_variant	1.0	rifampicin
rpoB	762404	c.2598T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762407	c.-963G>C	upstream_gene_variant	1.0	rifampicin
rpoB	762410	c.2604T>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	762416	c.2610A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	762434	c.-936T>C	upstream_gene_variant	1.0	rifampicin
rpoB	762449	c.2643C>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762452	c.2646G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762470	c.2664G>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoB	762491	c.2685T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	762512	c.-858C>G	upstream_gene_variant	0.88	rifampicin
rpoC	762527	c.-843G>C	upstream_gene_variant	0.95	rifampicin
rpoC	762533	c.-837T>C	upstream_gene_variant	0.94	rifampicin
rpoC	762536	c.-834T>C	upstream_gene_variant	1.0	rifampicin
rpoB	762537	c.2731_2733delTTGinsCC	frameshift_variant&missense_variant	1.0	rifampicin
rpoC	762551	c.-819C>T	upstream_gene_variant	1.0	rifampicin
rpoB	762785	p.Asp993Glu	missense_variant	0.9	rifampicin	Uncertain significance
rpoB	762786	p.Val994Lys	missense_variant	0.9	rifampicin
rpoB	762798	p.Ala998Ser	missense_variant	0.93	rifampicin
rpoB	762818	c.3012C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoB	762820	p.Phe1005Tyr	missense_variant	0.97	rifampicin
rpoB	762827	c.3021G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoB	762857	c.3051C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762863	c.3057T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762879	c.3073_3075delATGinsCC	frameshift_variant&missense_variant	1.0	rifampicin
rpoB	762929	c.3123G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	762995	c.3189G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763004	c.3198G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763007	c.3201C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763028	c.3222T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763031	c.3225T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763034	c.3228C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763040	c.3234C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763070	c.3264T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763085	c.3279C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763115	c.3309T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763127	c.3321G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763133	c.-237G>C	upstream_gene_variant	1.0	rifampicin
rpoB	763136	c.3330C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763139	c.-231C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763142	c.-228C>G	upstream_gene_variant	1.0	rifampicin
rpoC	763158	c.-212C>T	upstream_gene_variant	1.0	rifampicin
rpoB	763166	c.3360A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763179	c.-191C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763202	c.-168A>G	upstream_gene_variant	1.0	rifampicin
rpoC	763205	c.-165G>T	upstream_gene_variant	1.0	rifampicin
rpoC	763206	c.-164_-162delAGTinsTCG	upstream_gene_variant	1.0	rifampicin
rpoB	763214	c.3408T>C	synonymous_variant	0.91	rifampicin	Not assoc w R - Interim
rpoC	763217	c.-153G>C	upstream_gene_variant	1.0	rifampicin
rpoC	763226	c.-144A>G	upstream_gene_variant	1.0	rifampicin
rpoB	763227	p.Leu1141Met	missense_variant	1.0	rifampicin
rpoB	763235	p.Glu1143Asp	missense_variant	1.0	rifampicin
rpoB	763238	c.3432T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763241	p.Glu1145Asp	missense_variant	1.0	rifampicin
rpoC	763250	c.-120C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763251	c.-119C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763259	c.-111G>C	upstream_gene_variant	1.0	rifampicin
rpoB	763268	c.3462C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763283	c.3477T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763284	c.-86C>T	upstream_gene_variant	1.0	rifampicin
rpoC	763289	c.-81C>G	upstream_gene_variant	1.0	rifampicin
rpoC	763375	c.6C>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763396	c.27A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763402	c.33C>G	synonymous_variant	1.0	rifampicin
rpoC	763405	c.36C>T	synonymous_variant	0.98	rifampicin
rpoC	763408	c.39T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763414	c.45T>C	synonymous_variant	1.0	rifampicin
rpoC	763417	c.48C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763430	c.61A>C	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	763433	c.64_66delCAAinsAC	frameshift_variant&missense_variant	1.0	rifampicin
rpoC	763443	p.Tyr25Phe	missense_variant	1.0	rifampicin
rpoC	763447	c.78C>T	synonymous_variant	1.0	rifampicin
rpoC	763456	c.87A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763468	c.99G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763486	c.117T>G	synonymous_variant	1.0	rifampicin
rpoC	763528	c.159G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763546	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763573	c.204G>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	763594	c.225C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763660	c.291T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763675	c.306C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763702	c.333C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763703	c.334_336delTCGinsAGC	synonymous_variant	1.0	rifampicin
rpoC	763711	c.342G>C	synonymous_variant	1.0	rifampicin
rpoC	763717	c.348T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763723	c.354G>C	synonymous_variant	1.0	rifampicin
rpoC	763732	c.363C>G	synonymous_variant	1.0	rifampicin
rpoC	763735	c.366G>C	synonymous_variant	1.0	rifampicin
rpoC	763741	c.372C>T	synonymous_variant	1.0	rifampicin
rpoC	763744	c.375G>C	synonymous_variant	1.0	rifampicin
rpoC	763765	c.396T>C	synonymous_variant	1.0	rifampicin
rpoC	763768	c.399C>T	synonymous_variant	1.0	rifampicin
rpoC	763774	c.405G>C	synonymous_variant	1.0	rifampicin
rpoC	763781	p.Ser138Glu	missense_variant	1.0	rifampicin
rpoC	763807	c.438T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763813	c.444C>G	synonymous_variant	0.99	rifampicin
rpoC	763816	c.447C>G	synonymous_variant	0.99	rifampicin
rpoC	763822	c.453C>G	synonymous_variant	0.99	rifampicin
rpoC	763831	c.462A>G	synonymous_variant	0.98	rifampicin
rpoC	763837	c.468G>C	synonymous_variant	0.98	rifampicin
rpoC	763840	c.471G>C	synonymous_variant	0.98	rifampicin
rpoC	763849	c.480G>A	synonymous_variant	0.98	rifampicin
rpoC	763855	c.486C>T	synonymous_variant	0.96	rifampicin
rpoC	763858	c.489A>G	synonymous_variant	0.96	rifampicin
rpoC	763867	c.498C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763870	c.501C>T	synonymous_variant	0.96	rifampicin
rpoC	763871	p.Gly168Ser	missense_variant	0.96	rifampicin
rpoC	763876	p.Glu169Asp	missense_variant	0.96	rifampicin
rpoC	763879	c.510A>G	synonymous_variant	0.96	rifampicin
rpoC	763888	c.519G>T	synonymous_variant	0.95	rifampicin
rpoC	763894	c.525A>G	synonymous_variant	0.95	rifampicin
rpoC	763900	c.531G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763910	p.Leu181Met	missense_variant	0.96	rifampicin
rpoC	763933	c.564C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	763940	p.Ala191Ser	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	763945	c.576T>C	synonymous_variant	0.95	rifampicin
rpoC	763947	p.Ala193Val	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	763951	c.582G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763960	c.591T>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	763978	c.609C>T	synonymous_variant	0.96	rifampicin
rpoC	763996	c.627T>C	synonymous_variant	0.97	rifampicin
rpoC	764005	c.636G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764024	c.655_657delTTGinsCC	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	764032	p.Asp221Glu	missense_variant	1.0	rifampicin
rpoC	764040	p.Ser224Asn	missense_variant	1.0	rifampicin
rpoC	764044	c.675T>C	synonymous_variant	1.0	rifampicin
rpoC	764059	c.690G>C	synonymous_variant	1.0	rifampicin
rpoC	764083	c.714A>G	synonymous_variant	0.98	rifampicin
rpoC	764084	p.Asn239Val	missense_variant	0.98	rifampicin
rpoC	764098	c.729A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764101	c.732C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764102	p.Val245Gln	missense_variant	0.98	rifampicin
rpoC	764131	c.762T>C	synonymous_variant	0.96	rifampicin
rpoC	764147	c.778_780delTCGinsGC	frameshift_variant&missense_variant	0.95	rifampicin
rpoC	764153	p.Gln262Lys	missense_variant	0.95	rifampicin
rpoC	764156	p.Lys263Arg	missense_variant	0.95	rifampicin
rpoC	764188	c.819A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764203	c.834G>C	synonymous_variant	0.95	rifampicin
rpoC	764206	p.Asp279Glu	missense_variant	0.95	rifampicin
rpoC	764207	p.Val280Thr	missense_variant	0.95	rifampicin	Uncertain significance
rpoC	764215	c.846A>T	synonymous_variant	0.95	rifampicin
rpoC	764217	p.Asn283Ser	missense_variant	0.97	rifampicin
rpoC	764242	c.873C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764245	c.876C>G	synonymous_variant	0.95	rifampicin
rpoC	764248	c.879C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764257	c.888G>C	synonymous_variant	0.95	rifampicin
rpoC	764266	c.897T>G	synonymous_variant	0.93	rifampicin	Not assoc w R - Interim
rpoC	764269	c.900G>T	synonymous_variant	0.93	rifampicin
rpoC	764272	c.903G>C	synonymous_variant	0.94	rifampicin
rpoC	764278	c.909A>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764285	p.Gly306Ser	missense_variant	0.94	rifampicin
rpoC	764320	c.951C>T	synonymous_variant	0.95	rifampicin
rpoC	764338	c.969G>A	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764365	c.996C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764383	c.1014C>G	synonymous_variant	0.96	rifampicin
rpoC	764387	c.1018T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764405	c.1036_1038delAGGinsCC	frameshift_variant&missense_variant	0.96	rifampicin
rpoC	764410	c.1041G>C	synonymous_variant	0.97	rifampicin
rpoC	764431	c.1062G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764434	c.1065A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764452	c.1083T>C	synonymous_variant	0.96	rifampicin
rpoC	764458	c.1089G>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764461	c.1092A>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764485	c.1116G>C	synonymous_variant	0.96	rifampicin
rpoC	764491	c.1122G>T	synonymous_variant	0.97	rifampicin
rpoC	764497	c.1128A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764500	c.1131C>G	synonymous_variant	0.96	rifampicin
rpoC	764521	c.1152T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764527	c.1158C>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764536	c.1167G>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764539	c.1170C>G	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764575	c.1206T>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764578	c.1209C>G	synonymous_variant	0.95	rifampicin
rpoC	764585	c.1216_1218delCTCinsTG	frameshift_variant&missense_variant	0.95	rifampicin
rpoC	764611	c.1242G>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764632	c.1263T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764650	c.1281G>T	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764686	c.1317C>T	synonymous_variant	0.96	rifampicin
rpoC	764713	c.1344G>A	synonymous_variant	0.96	rifampicin
rpoC	764746	c.1377G>T	synonymous_variant	0.94	rifampicin	Not assoc w R - Interim
rpoC	764752	c.1383G>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764758	c.1389C>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	764791	c.1422C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764803	c.1434C>T	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764809	c.1440C>T	synonymous_variant	0.95	rifampicin	Not assoc w R
rpoC	764812	c.1443C>G	synonymous_variant	0.96	rifampicin
rpoC	764815	c.1446A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764824	c.1455T>C	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	764857	c.1488G>T	synonymous_variant	0.97	rifampicin
rpoC	764858	c.1489T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764875	c.1506C>G	synonymous_variant	0.98	rifampicin
rpoC	764878	c.1509C>G	synonymous_variant	0.98	rifampicin
rpoC	764887	c.1518G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	764888	c.1519_1521delTTGinsCC	frameshift_variant&missense_variant	0.99	rifampicin
rpoC	764893	c.1524T>C	synonymous_variant	0.99	rifampicin
rpoC	764911	c.1542A>G	synonymous_variant	0.99	rifampicin
rpoC	764923	c.1554A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	764932	c.1563C>G	synonymous_variant	0.98	rifampicin
rpoC	764948	c.1579T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764968	c.1599T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	764983	c.1614T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765007	c.1638T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765008	c.1639T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765011	c.1642_1644delAGCinsTCG	synonymous_variant	1.0	rifampicin
rpoC	765016	c.1647C>G	synonymous_variant	1.0	rifampicin
rpoC	765019	c.1650A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765034	c.1665T>G	synonymous_variant	1.0	rifampicin
rpoC	765040	c.1671T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765041	c.1672T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765047	c.1678T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765052	c.1683C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765055	c.1686C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765076	c.1707A>G	synonymous_variant	1.0	rifampicin
rpoC	765079	c.1710T>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765082	c.1713G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765089	c.1720T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	765103	c.1734G>T	synonymous_variant	1.0	rifampicin
rpoC	765349	c.1980T>C	synonymous_variant	0.88	rifampicin	Not assoc w R - Interim
rpoC	765357	p.Met663Thr	missense_variant	0.9	rifampicin
rpoC	765359	p.Ala664Thr	missense_variant	0.9	rifampicin
rpoC	765367	c.1998C>G	synonymous_variant	0.93	rifampicin
rpoC	765397	c.2028G>T	synonymous_variant	0.93	rifampicin
rpoC	765402	c.2035_2038delCTGG	frameshift_variant	0.93	rifampicin
rpoC	765409	c.2041_2042insCAGT	frameshift_variant	0.93	rifampicin
rpoC	765425	p.Lys686Glu	missense_variant	0.91	rifampicin
rpoC	765451	c.2082C>G	synonymous_variant	0.9	rifampicin
rpoC	765452	p.Ala695Arg	missense_variant	0.9	rifampicin
rpoC	765458	p.Ile697Val	missense_variant	0.91	rifampicin	Uncertain significance
rpoC	765466	c.2097C>T	synonymous_variant	0.92	rifampicin
rpoC	765478	c.2109T>G	synonymous_variant	0.92	rifampicin
rpoC	765496	c.2127C>G	synonymous_variant	0.92	rifampicin
rpoC	765499	c.2130C>G	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	765547	c.2178C>T	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoC	765548	c.2179_2181delAGCinsTCG	synonymous_variant	0.79	rifampicin
rpoC	765553	c.2184C>T	synonymous_variant	0.79	rifampicin	Not assoc w R - Interim
rpoC	765556	c.2187G>C	synonymous_variant	0.79	rifampicin
rpoC	765559	c.2190G>C	synonymous_variant	0.79	rifampicin
rpoC	765590	p.Arg741Glu	missense_variant	0.85	rifampicin
rpoC	765596	p.Lys743Gln	missense_variant	0.77	rifampicin
rpoC	765772	c.2403C>G	synonymous_variant	0.87	rifampicin
rpoC	765793	c.2424C>G	synonymous_variant	0.93	rifampicin
rpoC	765796	c.2427C>T	synonymous_variant	0.94	rifampicin
rpoC	765805	c.2436C>G	synonymous_variant	0.94	rifampicin
rpoC	765811	c.2442T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765814	c.2445A>G	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765826	c.2457T>C	synonymous_variant	0.95	rifampicin	Not assoc w R - Interim
rpoC	765875	p.Val836Ile	missense_variant	0.98	rifampicin	Uncertain significance
rpoC	765886	c.2517C>G	synonymous_variant	0.99	rifampicin
rpoC	765892	c.2523T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765937	c.2568T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765947	c.2578T>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	765961	c.2592G>T	synonymous_variant	0.98	rifampicin
rpoC	765962	c.2593_2595delTTGinsCT	frameshift_variant&synonymous_variant	0.97	rifampicin
rpoC	765967	c.2598C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765973	c.2604C>T	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765979	c.2610C>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	765982	c.2613C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	765994	c.2625A>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766012	c.2643C>G	synonymous_variant	0.96	rifampicin	Not assoc w R - Interim
rpoC	766021	c.2652G>C	synonymous_variant	0.94	rifampicin
rpoC	766043	p.Gln892Glu	missense_variant	0.88	rifampicin
rpoC	766270	c.2901G>C	synonymous_variant	0.89	rifampicin
rpoC	766273	c.2904T>C	synonymous_variant	0.89	rifampicin
rpoC	766280	p.Ser971Gly	missense_variant	0.9	rifampicin
rpoC	766298	p.Thr977Leu	missense_variant	0.92	rifampicin
rpoC	766309	c.2940G>C	synonymous_variant	0.92	rifampicin	Not assoc w R - Interim
rpoC	766315	c.2946C>G	synonymous_variant	0.92	rifampicin
rpoC	766321	c.2952C>G	synonymous_variant	0.92	rifampicin
rpoC	766324	c.2955C>G	synonymous_variant	0.92	rifampicin
rpoC	766333	c.2964G>C	synonymous_variant	0.93	rifampicin
rpoC	766345	c.2976T>C	synonymous_variant	0.95	rifampicin
rpoC	766348	c.2979A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766363	c.2994G>C	synonymous_variant	1.0	rifampicin
rpoC	766369	c.3000C>G	synonymous_variant	1.0	rifampicin
rpoC	766384	c.3015A>G	synonymous_variant	1.0	rifampicin
rpoC	766393	c.3024C>G	synonymous_variant	1.0	rifampicin
rpoC	766411	c.3042C>G	synonymous_variant	1.0	rifampicin
rpoC	766423	c.3054T>C	synonymous_variant	1.0	rifampicin
rpoC	766428	c.3060_3061insACC	conservative_inframe_insertion	1.0	rifampicin
rpoC	766432	c.3063T>C	synonymous_variant	1.0	rifampicin
rpoC	766434	c.3065_3066delAGinsGCAGC	missense_variant&conservative_inframe_insertion	1.0	rifampicin
rpoC	766456	c.3087C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766459	c.3090G>C	synonymous_variant	1.0	rifampicin
rpoC	766480	c.3111C>G	synonymous_variant	1.0	rifampicin
rpoC	766483	c.3114G>C	synonymous_variant	1.0	rifampicin
rpoC	766486	c.3117A>G	synonymous_variant	1.0	rifampicin
rpoC	766492	c.3123T>G	synonymous_variant	1.0	rifampicin
rpoC	766494	p.Gly1042Asp	missense_variant	1.0	rifampicin	Uncertain significance
rpoC	766517	p.Thr1050Ser	missense_variant	0.97	rifampicin
rpoC	766522	c.3153C>T	synonymous_variant	0.96	rifampicin
rpoC	766528	c.3159T>G	synonymous_variant	0.94	rifampicin
rpoC	766530	p.Arg1054Gln	missense_variant	0.87	rifampicin
rpoC	766540	p.Asp1057Glu	missense_variant	0.91	rifampicin
rpoC	766672	c.3303T>C	synonymous_variant	0.88	rifampicin
rpoC	766681	c.3312C>T	synonymous_variant	0.9	rifampicin
rpoC	766693	c.3324C>T	synonymous_variant	0.92	rifampicin
rpoC	766714	c.3345G>C	synonymous_variant	0.93	rifampicin
rpoC	766726	c.3357T>C	synonymous_variant	0.94	rifampicin
rpoC	766733	c.3364C>T	synonymous_variant	0.95	rifampicin
rpoC	766738	c.3369G>T	synonymous_variant	0.94	rifampicin
rpoC	766741	c.3372G>C	synonymous_variant	0.95	rifampicin
rpoC	766750	c.3381C>G	synonymous_variant	0.98	rifampicin
rpoC	766765	c.3396A>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766771	c.3402G>C	synonymous_variant	1.0	rifampicin
rpoC	766774	c.3405T>C	synonymous_variant	1.0	rifampicin
rpoC	766775	p.Arg1136Lys	missense_variant	1.0	rifampicin
rpoC	766801	c.3432C>T	synonymous_variant	0.98	rifampicin
rpoC	766804	c.3435A>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766843	c.3474T>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766846	c.3477C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766858	c.3489C>G	synonymous_variant	0.97	rifampicin
rpoC	766861	c.3492G>C	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766864	c.3495G>C	synonymous_variant	0.97	rifampicin
rpoC	766867	c.3498C>G	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766894	c.3525T>C	synonymous_variant	0.97	rifampicin
rpoC	766895	c.3526T>C	synonymous_variant	0.97	rifampicin
rpoC	766900	c.3531T>C	synonymous_variant	0.97	rifampicin
rpoC	766907	c.3538C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766911	p.Ile1181Thr	missense_variant	0.97	rifampicin
rpoC	766915	p.Asp1182Glu	missense_variant	0.97	rifampicin
rpoC	766918	c.3549C>T	synonymous_variant	0.97	rifampicin	Not assoc w R - Interim
rpoC	766933	c.3564A>C	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766942	c.3573C>T	synonymous_variant	0.99	rifampicin	Not assoc w R - Interim
rpoC	766945	c.3576A>G	synonymous_variant	0.98	rifampicin	Not assoc w R - Interim
rpoC	766951	c.3582G>T	synonymous_variant	0.99	rifampicin
rpoC	766963	c.3594T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766978	c.3609C>T	synonymous_variant	1.0	rifampicin
rpoC	766981	c.3612T>C	synonymous_variant	1.0	rifampicin
rpoC	766996	c.3627C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767002	c.3633G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767023	c.3654C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767038	c.3669G>A	synonymous_variant	1.0	rifampicin
rpoC	767098	c.3729T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767104	c.3735C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767119	c.3750A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767155	c.3786C>G	synonymous_variant	1.0	rifampicin
rpoC	767161	c.3792C>T	synonymous_variant	1.0	rifampicin
rpoC	767162	p.Asn1265Pro	missense_variant	1.0	rifampicin
rpoC	767167	c.3798C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767180	p.Ala1271Gln	missense_variant	1.0	rifampicin
rpoC	767197	c.3828G>A	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767221	c.3852C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767230	c.3861G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767233	c.3864T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767263	c.3894T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767264	p.Ala1299Gln	missense_variant	1.0	rifampicin
rpoC	767278	c.3909T>C	synonymous_variant	1.0	rifampicin
mmpL5	775796	c.2683_2685delTTTinsAG	frameshift_variant&stop_gained	0.82	clofazimine	Uncertain significance
mmpL5	775796	c.2683_2685delTTTinsAG	frameshift_variant&stop_gained	0.82	bedaquiline	Uncertain significance
mmpL5	775802	p.Met893Ile	missense_variant	0.5	clofazimine
mmpL5	775802	p.Met893Ile	missense_variant	0.5	bedaquiline
mmpL5	775817	c.2664T>C	synonymous_variant	0.87	clofazimine	Not assoc w R - Interim
mmpL5	775817	c.2664T>C	synonymous_variant	0.87	bedaquiline	Not assoc w R - Interim
mmpL5	775826	c.2655G>C	synonymous_variant	0.38	clofazimine
mmpL5	775826	c.2655G>C	synonymous_variant	0.38	bedaquiline
mmpL5	775829	c.2652C>G	synonymous_variant	0.72	clofazimine
mmpL5	775829	c.2652C>G	synonymous_variant	0.72	bedaquiline
mmpL5	775832	c.2649C>G	synonymous_variant	0.72	clofazimine
mmpL5	775832	c.2649C>G	synonymous_variant	0.72	bedaquiline
mmpL5	775835	c.2646C>G	synonymous_variant	0.74	clofazimine
mmpL5	775835	c.2646C>G	synonymous_variant	0.74	bedaquiline
mmpL5	775847	c.2634G>C	synonymous_variant	0.54	clofazimine
mmpL5	775847	c.2634G>C	synonymous_variant	0.54	bedaquiline
mmpL5	775856	c.2625T>C	synonymous_variant	0.9	clofazimine
mmpL5	775856	c.2625T>C	synonymous_variant	0.9	bedaquiline
mmpL5	775865	c.2616T>G	synonymous_variant	0.91	clofazimine
mmpL5	775865	c.2616T>G	synonymous_variant	0.91	bedaquiline
mmpL5	775886	c.2595A>C	synonymous_variant	0.95	clofazimine
mmpL5	775886	c.2595A>C	synonymous_variant	0.95	bedaquiline
mmpL5	775895	c.2584_2586delATCinsCG	frameshift_variant&missense_variant	0.5	clofazimine	Uncertain significance
mmpL5	775895	c.2584_2586delATCinsCG	frameshift_variant&missense_variant	0.5	bedaquiline	Uncertain significance
mmpL5	775898	c.2583G>A	synonymous_variant	0.5	clofazimine
mmpL5	775898	c.2583G>A	synonymous_variant	0.5	bedaquiline
mmpL5	775904	c.2577G>A	synonymous_variant	0.61	clofazimine
mmpL5	775904	c.2577G>A	synonymous_variant	0.61	bedaquiline
mmpL5	775907	c.2572_2574delCTCinsTG	frameshift_variant&synonymous_variant	0.61	clofazimine	Uncertain significance
mmpL5	775907	c.2572_2574delCTCinsTG	frameshift_variant&synonymous_variant	0.61	bedaquiline	Uncertain significance
mmpL5	775910	c.2571G>C	synonymous_variant	0.51	clofazimine
mmpL5	775910	c.2571G>C	synonymous_variant	0.51	bedaquiline
mmpL5	775913	c.2566_2568delGCCinsTA	frameshift_variant&missense_variant	0.6	clofazimine	Uncertain significance
mmpL5	775913	c.2566_2568delGCCinsTA	frameshift_variant&missense_variant	0.6	bedaquiline	Uncertain significance
mmpL5	775916	c.2565T>G	synonymous_variant	0.96	clofazimine
mmpL5	775916	c.2565T>G	synonymous_variant	0.96	bedaquiline
mmpL5	775939	p.Ala848Ser	missense_variant	0.47	clofazimine
mmpL5	775939	p.Ala848Ser	missense_variant	0.47	bedaquiline
mmpL5	775943	c.2538C>G	synonymous_variant	0.65	clofazimine
mmpL5	775943	c.2538C>G	synonymous_variant	0.65	bedaquiline
mmpL5	775946	c.2535C>G	synonymous_variant	0.78	clofazimine
mmpL5	775946	c.2535C>G	synonymous_variant	0.78	bedaquiline
mmpL5	775951	c.2530C>T	synonymous_variant	0.86	clofazimine
mmpL5	775951	c.2530C>T	synonymous_variant	0.86	bedaquiline
mmpL5	775955	p.Ile842Met	missense_variant	0.31	clofazimine
mmpL5	775955	p.Ile842Met	missense_variant	0.31	bedaquiline
mmpL5	775961	c.2520C>G	synonymous_variant	0.41	clofazimine
mmpL5	775961	c.2520C>G	synonymous_variant	0.41	bedaquiline
mmpL5	775966	p.Ala839Ser	missense_variant	0.89	clofazimine
mmpL5	775966	p.Ala839Ser	missense_variant	0.89	bedaquiline
mmpL5	775975	p.Leu836Met	missense_variant	1.0	clofazimine
mmpL5	775975	p.Leu836Met	missense_variant	1.0	bedaquiline
mmpL5	775981	p.Leu834Met	missense_variant	1.0	clofazimine
mmpL5	775981	p.Leu834Met	missense_variant	1.0	bedaquiline
mmpL5	775991	c.2488_2490delGAGinsAC	frameshift_variant&missense_variant	0.62	clofazimine	Uncertain significance
mmpL5	775991	c.2488_2490delGAGinsAC	frameshift_variant&missense_variant	0.62	bedaquiline	Uncertain significance
mmpL5	775997	c.2484T>G	synonymous_variant	1.0	clofazimine
mmpL5	775997	c.2484T>G	synonymous_variant	1.0	bedaquiline
mmpL5	776000	c.2481G>C	synonymous_variant	0.61	clofazimine
mmpL5	776000	c.2481G>C	synonymous_variant	0.61	bedaquiline
mmpL5	776009	c.2472A>G	synonymous_variant	0.9	clofazimine
mmpL5	776009	c.2472A>G	synonymous_variant	0.9	bedaquiline
mmpL5	776015	c.2464_2466delATCinsTG	frameshift_variant&missense_variant	0.39	clofazimine	Uncertain significance
mmpL5	776015	c.2464_2466delATCinsTG	frameshift_variant&missense_variant	0.39	bedaquiline	Uncertain significance
mmpL5	776018	c.2461_2463delCTGinsTC	frameshift_variant&synonymous_variant	0.56	clofazimine	Uncertain significance
mmpL5	776018	c.2461_2463delCTGinsTC	frameshift_variant&synonymous_variant	0.56	bedaquiline	Uncertain significance
mmpL5	776021	c.2458_2460delGTGinsAC	frameshift_variant&missense_variant	0.55	clofazimine	Uncertain significance
mmpL5	776021	c.2458_2460delGTGinsAC	frameshift_variant&missense_variant	0.55	bedaquiline	Uncertain significance
mmpL5	776030	c.2451G>C	synonymous_variant	0.96	clofazimine
mmpL5	776030	c.2451G>C	synonymous_variant	0.96	bedaquiline
mmpL5	776039	c.2442C>T	synonymous_variant	0.35	clofazimine
mmpL5	776039	c.2442C>T	synonymous_variant	0.35	bedaquiline
mmpL5	776053	p.Leu810Val	missense_variant	0.66	clofazimine
mmpL5	776053	p.Leu810Val	missense_variant	0.66	bedaquiline
mmpL5	776060	c.2421C>G	synonymous_variant	0.91	clofazimine
mmpL5	776060	c.2421C>G	synonymous_variant	0.91	bedaquiline
mmpL5	776072	c.2409C>G	synonymous_variant	0.71	clofazimine
mmpL5	776072	c.2409C>G	synonymous_variant	0.71	bedaquiline
mmpL5	776075	c.2406C>G	synonymous_variant	0.69	clofazimine
mmpL5	776075	c.2406C>G	synonymous_variant	0.69	bedaquiline
mmpL5	776078	c.2403C>G	synonymous_variant	0.93	clofazimine
mmpL5	776078	c.2403C>G	synonymous_variant	0.93	bedaquiline
mmpL5	776081	c.2400G>C	synonymous_variant	0.6	clofazimine
mmpL5	776081	c.2400G>C	synonymous_variant	0.6	bedaquiline
mmpL5	776087	c.2394C>G	synonymous_variant	0.93	clofazimine
mmpL5	776087	c.2394C>G	synonymous_variant	0.93	bedaquiline
mmpL5	776093	c.2388C>A	synonymous_variant	0.67	clofazimine
mmpL5	776093	c.2388C>A	synonymous_variant	0.67	bedaquiline
mmpL5	776100	p.Thr794Ile	missense_variant	1.0	clofazimine	Not assoc w R
mmpL5	776100	p.Thr794Ile	missense_variant	1.0	bedaquiline	Not assoc w R - Interim
rpsL	781592	c.33T>G	synonymous_variant	0.86	streptomycin
rpsL	781595	c.36T>C	synonymous_variant	0.93	streptomycin
rpsL	781598	c.39G>T	synonymous_variant	0.86	streptomycin
rpsL	781605	p.Ile16Pro	missense_variant	0.86	streptomycin
rpsL	781608	c.49_51delAGTinsGC	frameshift_variant&missense_variant	0.86	streptomycin	Uncertain significance
rpsL	781616	c.57C>G	synonymous_variant	0.86	streptomycin
rpsL	781617	p.Lys20Arg	missense_variant	0.86	streptomycin
rpsL	781620	p.Thr21Val	missense_variant	0.86	streptomycin
rpsL	781625	c.66G>C	synonymous_variant	0.86	streptomycin
rpsL	781628	c.69T>A	synonymous_variant	0.87	streptomycin
rpsL	781631	c.72G>C	synonymous_variant	0.88	streptomycin
rpsL	781649	c.90T>C	synonymous_variant	0.93	streptomycin
rpsL	781652	c.93T>C	synonymous_variant	0.93	streptomycin
rpsL	781655	c.96T>C	synonymous_variant	0.93	streptomycin
rpsL	781658	c.99A>G	synonymous_variant	0.93	streptomycin
rpsL	781682	c.123T>C	synonymous_variant	0.98	streptomycin
rpsL	781709	c.150G>C	synonymous_variant	0.98	streptomycin	Not assoc w R - Interim
rpsL	781715	c.156T>C	synonymous_variant	0.98	streptomycin
rpsL	781718	c.159C>A	synonymous_variant	0.98	streptomycin
rpsL	781728	c.169T>C	synonymous_variant	0.97	streptomycin
rpsL	781733	c.174G>C	synonymous_variant	0.97	streptomycin
rpsL	781735	p.Ser59Thr	missense_variant	0.97	streptomycin
rpsL	781751	c.192G>C	synonymous_variant	0.98	streptomycin
rpsL	781754	c.195G>C	synonymous_variant	0.98	streptomycin
rpsL	781760	c.201T>C	synonymous_variant	0.96	streptomycin
rpsL	781763	c.204C>G	synonymous_variant	0.96	streptomycin
rpsL	781793	c.234G>C	synonymous_variant	0.97	streptomycin
rpsL	781808	c.249C>T	synonymous_variant	0.98	streptomycin
rpsL	781814	c.255C>T	synonymous_variant	0.98	streptomycin
rpsL	781817	c.258G>T	synonymous_variant	0.97	streptomycin
rpsL	781832	c.273T>G	synonymous_variant	0.98	streptomycin
rpsL	781859	c.300T>C	synonymous_variant	0.98	streptomycin	Not assoc w R - Interim
rpsL	781865	c.306G>C	synonymous_variant	0.98	streptomycin
rpsL	781868	c.309T>C	synonymous_variant	0.98	streptomycin
rpsL	781871	c.312G>C	synonymous_variant	0.98	streptomycin
rpsL	781880	c.321C>G	synonymous_variant	0.98	streptomycin
rpsL	781892	c.333A>G	synonymous_variant	0.98	streptomycin
rpsL	781904	c.345C>T	synonymous_variant	1.0	streptomycin	Not assoc w R - Interim
rpsL	781907	c.348T>C	synonymous_variant	1.0	streptomycin
rpsL	781916	c.357T>C	synonymous_variant	1.0	streptomycin
rpsL	781929	p.Gly124Ser	missense_variant	1.0	streptomycin	Uncertain significance
rplC	800516	c.-293G>C	upstream_gene_variant	0.93	linezolid
rplC	800531	c.-278T>C	upstream_gene_variant	0.94	linezolid
rplC	800537	c.-272C>G	upstream_gene_variant	0.95	linezolid
rplC	800540	c.-269T>C	upstream_gene_variant	0.95	linezolid
rplC	800546	c.-263T>C	upstream_gene_variant	0.97	linezolid
rplC	800567	c.-242A>G	upstream_gene_variant	0.95	linezolid
rplC	800570	c.-239C>G	upstream_gene_variant	0.95	linezolid
rplC	800574	c.-235_-234delGTinsAC	upstream_gene_variant	0.95	linezolid
rplC	800579	c.-230C>G	upstream_gene_variant	0.95	linezolid
rplC	800582	c.-227C>G	upstream_gene_variant	0.95	linezolid
rplC	800585	c.-224T>C	upstream_gene_variant	0.95	linezolid
rplC	800594	c.-215C>G	upstream_gene_variant	0.95	linezolid
rplC	800597	c.-212A>C	upstream_gene_variant	0.95	linezolid
rplC	800600	c.-209G>C	upstream_gene_variant	0.95	linezolid
rplC	800612	c.-197A>G	upstream_gene_variant	0.96	linezolid
rplC	800618	c.-191T>C	upstream_gene_variant	0.98	linezolid
rplC	800633	c.-176T>C	upstream_gene_variant	0.98	linezolid
rplC	800654	c.-155T>C	upstream_gene_variant	0.98	linezolid
rplC	800693	c.-116A>C	upstream_gene_variant	0.97	linezolid
rplC	800702	c.-107G>A	upstream_gene_variant	0.97	linezolid
rplC	800703	c.-106T>C	upstream_gene_variant	0.97	linezolid
rplC	800715	c.-94A>C	upstream_gene_variant	0.98	linezolid
rplC	800720	c.-89T>C	upstream_gene_variant	0.98	linezolid
rplC	800723	c.-86C>G	upstream_gene_variant	0.98	linezolid
rplC	800735	c.-74C>G	upstream_gene_variant	0.98	linezolid
rplC	800738	c.-71T>C	upstream_gene_variant	0.98	linezolid
rplC	800747	c.-62C>G	upstream_gene_variant	0.98	linezolid
rplC	800762	c.-47T>G	upstream_gene_variant	0.98	linezolid
rplC	800774	c.-35C>T	upstream_gene_variant	0.98	linezolid
rplC	800799	c.-10_-8delGGAinsC	upstream_gene_variant	0.94	linezolid
rplC	800807	c.-2C>A	upstream_gene_variant	0.94	linezolid
rplC	800814	c.6A>T	synonymous_variant	0.94	linezolid
rplC	800815	c.7_9delCGAinsAG	frameshift_variant&synonymous_variant	0.94	linezolid
rplC	800829	c.21C>G	synonymous_variant	0.95	linezolid
rplC	800832	c.24T>C	synonymous_variant	0.96	linezolid
rplC	800844	c.36T>C	synonymous_variant	0.96	linezolid
rplC	800856	c.48A>G	synonymous_variant	0.98	linezolid
rplC	800865	c.57A>G	synonymous_variant	0.98	linezolid
rplC	800867	p.Ser20Asn	missense_variant	0.98	linezolid
rplC	800874	c.66A>G	synonymous_variant	0.98	linezolid
rplC	800877	c.69A>C	synonymous_variant	0.98	linezolid
rplC	800880	c.72A>G	synonymous_variant	0.98	linezolid
rplC	800889	c.81C>G	synonymous_variant	0.98	linezolid
rplC	800892	c.84G>C	synonymous_variant	0.98	linezolid
rplC	800904	c.96G>C	synonymous_variant	1.0	linezolid
rplC	800913	c.105G>C	synonymous_variant	0.98	linezolid
rplC	800916	c.108A>C	synonymous_variant	0.98	linezolid
rplC	800919	c.111C>G	synonymous_variant	0.98	linezolid
rplC	800931	c.123G>T	synonymous_variant	0.98	linezolid
rplC	800937	c.129A>G	synonymous_variant	0.97	linezolid
rplC	800946	c.138T>C	synonymous_variant	1.0	linezolid
rplC	800949	c.141T>C	synonymous_variant	1.0	linezolid
rplC	800970	c.162T>C	synonymous_variant	1.0	linezolid	Not assoc w R - Interim
rplC	800981	p.Ser58Asn	missense_variant	1.0	linezolid
rplC	800985	c.177A>G	synonymous_variant	1.0	linezolid
rplC	800994	c.186C>G	synonymous_variant	1.0	linezolid
rplC	801008	p.Thr67Lys	missense_variant	1.0	linezolid
rplC	801019	p.Thr71Glu	missense_variant	1.0	linezolid
rplC	801027	c.219C>G	synonymous_variant	1.0	linezolid
rplC	801117	c.309G>C	synonymous_variant	1.0	linezolid
rplC	801127	p.Ala107Thr	missense_variant	1.0	linezolid
rplC	801132	c.324T>C	synonymous_variant	1.0	linezolid
rplC	801156	c.348T>C	synonymous_variant	1.0	linezolid
rplC	801160	c.352_353delTCinsAG	synonymous_variant	1.0	linezolid
rplC	801171	c.363A>G	synonymous_variant	1.0	linezolid
rplC	801174	c.366T>C	synonymous_variant	0.98	linezolid
rplC	801180	c.372C>G	synonymous_variant	0.98	linezolid
rplC	801195	c.387G>C	synonymous_variant	0.98	linezolid
rplC	801201	c.393C>T	synonymous_variant	0.96	linezolid
rplC	801210	c.402T>C	synonymous_variant	0.98	linezolid
rplC	801222	c.414T>C	synonymous_variant	0.98	linezolid
rplC	801228	c.420T>C	synonymous_variant	0.98	linezolid
rplC	801229	p.Ala141Thr	missense_variant	0.98	linezolid
rplC	801252	c.444G>C	synonymous_variant	0.98	linezolid
rplC	801255	c.447C>T	synonymous_variant	0.98	linezolid
rplC	801267	c.459A>C	synonymous_variant	0.98	linezolid
rplC	801270	c.462T>C	synonymous_variant	0.98	linezolid
rplC	801273	c.465C>G	synonymous_variant	0.98	linezolid
rplC	801281	p.Ala158Gly	missense_variant	0.98	linezolid
rplC	801303	c.495G>C	synonymous_variant	0.98	linezolid
rplC	801309	c.501C>G	synonymous_variant	0.95	linezolid
rplC	801312	c.504G>C	synonymous_variant	0.94	linezolid
rplC	801324	c.516T>C	synonymous_variant	1.0	linezolid
rplC	801330	c.522G>C	synonymous_variant	0.95	linezolid
rplC	801331	c.523_525delGTGinsAC	frameshift_variant&missense_variant	0.95	linezolid
rplC	801337	p.Val177Thr	missense_variant	0.95	linezolid
rplC	801341	p.Leu178Gln	missense_variant	0.95	linezolid
rplC	801348	c.540T>G	synonymous_variant	0.95	linezolid
rplC	801357	c.549T>C	synonymous_variant	0.9	linezolid
rplC	801385	c.577C>T	synonymous_variant	0.82	linezolid
fbiC	1303497	c.567G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303506	c.576C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303509	c.579G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303512	c.582T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303531	p.Met201Leu	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303545	c.615A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303551	c.621G>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303971	c.1041T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303977	c.1047C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303980	c.1050G>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1303995	c.1065C>T	synonymous_variant	1.0	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1303998	c.1068T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304001	c.1071C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304004	c.1074A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304008	c.1078T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304013	c.1083G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304019	c.1089C>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304022	c.1092T>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304031	c.1101C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304040	c.1110C>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304048	p.Ala373Gly	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304092	p.Met388Leu	missense_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304106	c.1176G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304118	c.1188C>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304127	c.1197A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304133	c.1203G>A	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304571	c.1641G>C	synonymous_variant	0.93	clofazimine
					pretomanid
					delamanid
fbiC	1304577	c.1647C>T	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fbiC	1304580	c.1650T>C	synonymous_variant	0.9	clofazimine
					pretomanid
					delamanid
fbiC	1304607	c.1677C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304610	c.1680C>G	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiC	1304613	c.1683T>A	synonymous_variant	0.91	clofazimine
					pretomanid
					delamanid
fbiC	1304625	c.1695C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304631	c.1701C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304640	c.1710A>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304652	c.1722C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304655	c.1725C>T	synonymous_variant	0.95	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304658	c.1728C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304670	c.1740G>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304675	p.Gly582Asp	missense_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304694	c.1764A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304703	c.1773C>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304709	c.1779C>G	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304715	c.1785G>C	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304724	c.1794A>G	synonymous_variant	0.96	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304727	c.1797A>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304748	c.1818T>C	synonymous_variant	0.98	clofazimine
					pretomanid
					delamanid
fbiC	1304751	c.1821C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304754	c.1824G>A	synonymous_variant	0.95	clofazimine
					pretomanid
					delamanid
fbiC	1304757	c.1827A>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304763	c.1833C>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304769	c.1839C>T	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304772	c.1842C>T	synonymous_variant	0.97	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304778	c.1848T>C	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304784	c.1854T>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304787	c.1857T>G	synonymous_variant	0.97	clofazimine
					pretomanid
					delamanid
fbiC	1304808	c.1878C>A	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304811	c.1881C>G	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304817	c.1887T>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304826	c.1896G>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304829	c.1899T>C	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304832	c.1902C>G	synonymous_variant	0.94	clofazimine	Not assoc w R - Interim
					pretomanid
					delamanid	Not assoc w R - Interim
fbiC	1304835	c.1905G>A	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304856	c.1926C>G	synonymous_variant	0.96	clofazimine
					pretomanid
					delamanid
fbiC	1304868	c.1938G>A	synonymous_variant	0.94	clofazimine
					pretomanid
					delamanid
fbiC	1304871	c.1941G>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304872	c.1942_1944delAGCinsTCG	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304877	c.1947T>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304887	c.1957C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304894	p.Gly655Ala	missense_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304901	c.1971C>G	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304910	c.1980G>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304916	c.1986T>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304922	c.1992C>T	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304925	c.1995G>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304928	c.1998T>C	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304931	c.2001C>G	synonymous_variant	0.92	clofazimine
					pretomanid
					delamanid
fbiC	1304937	c.2007G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304940	c.2010A>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304946	c.2016G>C	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304958	c.2028T>G	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
fbiC	1304967	c.2037G>T	synonymous_variant	1.0	clofazimine
					pretomanid
					delamanid
sigE	1364667	c.255T>C	synonymous_variant	0.91	pyrazinamide
sigE	1364676	c.264C>G	synonymous_variant	0.92	pyrazinamide
sigE	1364703	c.291G>C	synonymous_variant	0.95	pyrazinamide
sigE	1364709	c.297T>C	synonymous_variant	0.95	pyrazinamide
sigE	1364712	c.300T>C	synonymous_variant	0.96	pyrazinamide
sigE	1364718	c.306C>T	synonymous_variant	0.96	pyrazinamide
sigE	1364727	c.315C>T	synonymous_variant	0.96	pyrazinamide
sigE	1364736	c.324T>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
sigE	1364742	c.330A>G	synonymous_variant	0.97	pyrazinamide
sigE	1364763	c.351T>C	synonymous_variant	0.96	pyrazinamide
sigE	1364767	c.355_357delAGGinsCC	frameshift_variant&missense_variant	0.96	pyrazinamide	Uncertain significance
sigE	1364772	c.360G>C	synonymous_variant	0.96	pyrazinamide
sigE	1364778	c.366G>C	synonymous_variant	0.92	pyrazinamide
sigE	1364782	c.370_372delGTCinsCG	frameshift_variant&missense_variant	0.92	pyrazinamide	Uncertain significance
sigE	1364790	c.378T>C	synonymous_variant	0.92	pyrazinamide
sigE	1364799	c.387G>C	synonymous_variant	0.93	pyrazinamide
sigE	1364805	c.393C>G	synonymous_variant	0.97	pyrazinamide
sigE	1364811	c.399A>G	synonymous_variant	0.93	pyrazinamide
sigE	1364818	c.406_408delCTAinsTG	frameshift_variant&stop_gained	0.93	pyrazinamide	Uncertain significance
sigE	1364832	c.420C>G	synonymous_variant	0.93	pyrazinamide
sigE	1364835	c.423C>G	synonymous_variant	0.93	pyrazinamide
sigE	1364839	c.427T>C	synonymous_variant	0.93	pyrazinamide
sigE	1364847	c.435G>C	synonymous_variant	0.92	pyrazinamide
sigE	1364856	c.444C>G	synonymous_variant	0.91	pyrazinamide
sigE	1364862	c.450C>G	synonymous_variant	0.9	pyrazinamide
sigE	1364868	c.456T>C	synonymous_variant	0.88	pyrazinamide
sigE	1364877	c.465G>A	synonymous_variant	0.88	pyrazinamide
sigE	1364883	c.471G>A	synonymous_variant	0.92	pyrazinamide
sigE	1364886	c.474G>A	synonymous_variant	0.9	pyrazinamide
sigE	1364887	c.475_477delTTAinsCG	frameshift_variant&missense_variant	0.9	pyrazinamide	Uncertain significance
sigE	1364892	c.480C>G	synonymous_variant	0.92	pyrazinamide
sigE	1364904	p.Asp164Glu	missense_variant	0.95	pyrazinamide
sigE	1364919	c.507T>C	synonymous_variant	0.95	pyrazinamide
sigE	1364920	p.Glu170Ser	missense_variant	0.95	pyrazinamide
sigE	1364950	c.538_540delGCAinsTG	frameshift_variant&stop_gained	1.0	pyrazinamide	Uncertain significance
sigE	1364956	c.544C>T	synonymous_variant	1.0	pyrazinamide
sigE	1364961	c.549A>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
sigE	1364964	c.552T>C	synonymous_variant	1.0	pyrazinamide	Not assoc w R - Interim
sigE	1364976	c.564T>C	synonymous_variant	0.94	pyrazinamide	Not assoc w R - Interim
sigE	1364979	c.567C>G	synonymous_variant	0.93	pyrazinamide
sigE	1364980	c.568_570delTTGinsCC	frameshift_variant&missense_variant	0.93	pyrazinamide	Uncertain significance
sigE	1364984	p.Ala191Asp	missense_variant	0.93	pyrazinamide
sigE	1364994	c.582G>C	synonymous_variant	0.93	pyrazinamide
sigE	1365000	c.588G>A	synonymous_variant	0.93	pyrazinamide	Not assoc w R - Interim
sigE	1365006	c.594T>C	synonymous_variant	0.93	pyrazinamide
sigE	1365015	c.603G>C	synonymous_variant	0.93	pyrazinamide
sigE	1365024	c.612T>C	synonymous_variant	0.93	pyrazinamide
sigE	1365042	c.630G>C	synonymous_variant	0.92	pyrazinamide
rrs	1471923	n.78T>C	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471925	n.80T>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471932	n.87A>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471934	n.89A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1471936	n.91A>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1471986	n.141C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472019	n.174G>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472022	n.178_181delGGAC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472030	n.185delGinsCCTGCT	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472033	n.188A>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472034	n.189T>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472040	n.195delTinsGC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472043	n.198T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472048	n.203T>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472053	n.211_212delGC	non_coding_transcript_exon_variant	0.97	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472061	n.216A>T	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472279	n.434T>C	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472286	n.441C>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472287	n.442C>T	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472297	n.453_454delGT	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472303	n.458_470delGGTTCTCTCGGATinsTGAGG	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472327	n.482G>A	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472328	n.483G>C	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin
					capreomycin
					amikacin
rrs	1472446	n.601T>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472452	n.607G>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472464	n.619A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472489	n.644A>G	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472973	n.1128A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473104	n.1259C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473110	n.1265T>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473111	n.1266A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473123	n.1278delAinsTC	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473276	n.1431A>G	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473289	n.1444T>G	non_coding_transcript_exon_variant	0.99	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473290	n.1445_1446insAA	non_coding_transcript_exon_variant	0.98	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473301	n.1456T>C	non_coding_transcript_exon_variant	0.99	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.93	capreomycin	Uncertain significance
rrl	1473668	n.11C>T	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1473696	n.39T>C	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473696	n.39T>C	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473697	n.40C>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473697	n.40C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473699	n.42A>G	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473699	n.42A>G	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1473743	n.86C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1473743	n.86C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1473770	n.113T>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473788	n.131A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473807	n.150T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473811	n.154C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473811	n.154C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473813	n.156C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473813	n.156C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473814	n.157A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473814	n.157A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473815	n.158T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473815	n.158T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473816	n.159C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473816	n.159C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473822	n.165A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473822	n.165A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473828	n.171G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473828	n.171G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473829	n.172G>C	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1473829	n.172G>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473830	n.173T>G	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1473830	n.173T>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473831	n.174G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473831	n.174G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473833	n.176G>T	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1473833	n.176G>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1473836	n.179A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473836	n.179A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473876	n.219G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474174	n.517A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474185	n.528G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474186	n.529A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474202	n.545T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474202	n.545T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474282	n.625G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474282	n.625G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474287	n.630delTinsCCC	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474287	n.630delTinsCCC	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474293	n.637_644delCCTCTCCG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474293	n.637_644delCCTCTCCG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474303	n.646A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474303	n.646A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474306	n.649A>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474306	n.649A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474308	n.653_654delTG	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474308	n.653_654delTG	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474350	n.693G>C	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1474350	n.693G>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474351	n.694G>C	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474351	n.694G>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474374	n.717T>G	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474374	n.717T>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474413	n.756_757delACinsTAT	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474413	n.756_757delACinsTAT	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474418	n.761C>A	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474418	n.761C>A	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474421	n.764_767delGCGCinsA	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474421	n.764_767delGCGCinsA	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474437	n.780_781delGAinsTTGGT	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474437	n.780_781delGAinsTTGGT	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474439	n.782A>G	non_coding_transcript_exon_variant	0.97	capreomycin
rrl	1474439	n.782A>G	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1474446	n.789C>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474446	n.789C>T	non_coding_transcript_exon_variant	0.98	linezolid	Uncertain significance
rrl	1474452	n.795C>G	non_coding_transcript_exon_variant	0.98	capreomycin
rrl	1474452	n.795C>G	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474626	n.969T>C	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474627	n.970G>A	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474629	n.972G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474629	n.972G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474632	n.975G>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474636	n.979A>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474637	n.980C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474638	n.981C>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1474639	n.982G>T	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1474639	n.982G>T	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1474710	n.1053delTinsACAA	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474710	n.1053delTinsACAA	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474720	n.1063C>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1474720	n.1063C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474753	n.1096A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474760	n.1103A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1474830	n.1173A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475031	n.1374G>T	non_coding_transcript_exon_variant	0.97	linezolid
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475061	n.1404C>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475088	n.1431A>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475088	n.1431A>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475202	n.1545G>A	non_coding_transcript_exon_variant	0.92	capreomycin
rrl	1475202	n.1545G>A	non_coding_transcript_exon_variant	0.92	linezolid
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	0.91	capreomycin	Uncertain significance
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	0.91	linezolid
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475333	n.1676T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475333	n.1676T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475369	n.1712G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475379	n.1722G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475379	n.1722G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475380	n.1723C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475381	n.1724G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475381	n.1724G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475382	n.1725A>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475382	n.1725A>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475393	n.1737_1738insGATG	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475393	n.1737_1738insGATG	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475397	n.1741_1745delCTCAC	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475397	n.1741_1745delCTCAC	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475404	n.1747A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475404	n.1747A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475405	n.1748A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475405	n.1748A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475429	n.1772G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475430	n.1773T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475430	n.1773T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475452	n.1795C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475458	n.1801C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475458	n.1801C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475460	n.1803A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475460	n.1803A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475480	n.1823A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475480	n.1823A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475532	n.1875A>G	non_coding_transcript_exon_variant	0.97	capreomycin	Uncertain significance
rrl	1475532	n.1875A>G	non_coding_transcript_exon_variant	0.97	linezolid	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475544	n.1887A>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475545	n.1888T>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475602	n.1945G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475603	n.1946G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475603	n.1946G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.98	capreomycin	Uncertain significance
rrl	1475604	n.1947A>C	non_coding_transcript_exon_variant	0.98	linezolid
rrl	1475606	n.1949T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475606	n.1949T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475613	n.1956A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475613	n.1956A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475615	n.1958C>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475615	n.1958C>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475616	n.1959A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475626	n.1969T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475626	n.1969T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475627	n.1970G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475627	n.1970G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475628	n.1971G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475628	n.1971G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475629	n.1972G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475629	n.1972G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475637	n.1980T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475638	n.1981C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475639	n.1982C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475643	n.1986C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475643	n.1986C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475647	n.1990G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475659	n.2002G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475707	n.2050T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475707	n.2050T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1475756	n.2099T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475884	n.2227A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475916	n.2259C>T	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.99	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.99	linezolid	Uncertain significance
rrl	1475991	n.2334T>C	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475991	n.2334T>C	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	0.99	capreomycin	Uncertain significance
rrl	1475995	n.2338G>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476030	n.2373A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476033	n.2376T>G	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476033	n.2376T>G	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476034	n.2377C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476034	n.2377C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476035	n.2378G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476035	n.2378G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476044	n.2387T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476045	n.2388G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476045	n.2388G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476046	n.2389G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476046	n.2389G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476058	n.2401T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476058	n.2401T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476088	n.2431A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476165	n.2508T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476165	n.2508T>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476214	n.2557G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476215	n.2558C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476251	n.2594T>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476251	n.2594T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476252	n.2595T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476252	n.2595T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476256	n.2599A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476256	n.2599A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476529	n.2872A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476529	n.2872A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476583	n.2926G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476597	n.2940G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476628	n.2971T>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476674	n.3017T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476679	n.3022T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476679	n.3022T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476689	n.3032A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476692	n.3035T>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476692	n.3035T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.99	capreomycin
rrl	1476695	n.3038T>A	non_coding_transcript_exon_variant	0.99	linezolid
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476723	n.3066T>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476731	n.3074G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476732	n.3075T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476740	n.3083G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476740	n.3083G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476741	n.3084G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476741	n.3084G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476743	n.3086A>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476743	n.3086A>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476744	n.3087G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476744	n.3087G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476746	n.3089T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476746	n.3089T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476750	n.3093T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476757	n.3100T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476757	n.3100T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476759	n.3102T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476770	n.3113T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476771	n.3114G>A	non_coding_transcript_exon_variant	1.0	linezolid
inhA	1673667	c.-535A>G	upstream_gene_variant	0.73	ethionamide
inhA	1673667	c.-535A>G	upstream_gene_variant	0.73	isoniazid
inhA	1673679	c.-523T>C	upstream_gene_variant	0.73	ethionamide	Uncertain significance
inhA	1673679	c.-523T>C	upstream_gene_variant	0.73	isoniazid	Uncertain significance
inhA	1673682	c.-520G>C	upstream_gene_variant	0.75	ethionamide	Uncertain significance
inhA	1673682	c.-520G>C	upstream_gene_variant	0.75	isoniazid	Uncertain significance
inhA	1673692	c.-510C>G	upstream_gene_variant	0.77	ethionamide	Uncertain significance
inhA	1673692	c.-510C>G	upstream_gene_variant	0.77	isoniazid	Uncertain significance
inhA	1673697	c.-505G>C	upstream_gene_variant	0.77	ethionamide
inhA	1673697	c.-505G>C	upstream_gene_variant	0.77	isoniazid
fabG1	1673710	c.271_273delCTAinsAC	frameshift_variant&missense_variant	0.77	ethionamide
fabG1	1673710	c.271_273delCTAinsAC	frameshift_variant&missense_variant	0.77	isoniazid
fabG1	1673716	p.Ala93Lys	missense_variant	0.77	ethionamide
fabG1	1673716	p.Ala93Lys	missense_variant	0.77	isoniazid
inhA	1673724	c.-478A>G	upstream_gene_variant	0.77	ethionamide
inhA	1673724	c.-478A>G	upstream_gene_variant	0.77	isoniazid
inhA	1673727	c.-475C>T	upstream_gene_variant	0.77	ethionamide
inhA	1673727	c.-475C>T	upstream_gene_variant	0.77	isoniazid	Uncertain significance
fabG1	1673733	p.Met98Ile	missense_variant	0.77	ethionamide
fabG1	1673733	p.Met98Ile	missense_variant	0.77	isoniazid
inhA	1673736	c.-466G>A	upstream_gene_variant	0.77	ethionamide
inhA	1673736	c.-466G>A	upstream_gene_variant	0.77	isoniazid
inhA	1673748	c.-454A>G	upstream_gene_variant	0.91	ethionamide
inhA	1673748	c.-454A>G	upstream_gene_variant	0.91	isoniazid
fabG1	1673749	p.Lys104Arg	missense_variant	0.91	ethionamide
fabG1	1673749	p.Lys104Arg	missense_variant	0.91	isoniazid
fabG1	1673758	p.Lys107Glu	missense_variant	0.91	ethionamide
fabG1	1673758	p.Lys107Glu	missense_variant	0.91	isoniazid
inhA	1673784	c.-418G>C	upstream_gene_variant	0.95	ethionamide
inhA	1673784	c.-418G>C	upstream_gene_variant	0.95	isoniazid
inhA	1673799	c.-403T>C	upstream_gene_variant	1.0	ethionamide
inhA	1673799	c.-403T>C	upstream_gene_variant	1.0	isoniazid
inhA	1673802	c.-400A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673802	c.-400A>G	upstream_gene_variant	1.0	isoniazid
inhA	1673805	c.-397G>C	upstream_gene_variant	1.0	ethionamide
inhA	1673805	c.-397G>C	upstream_gene_variant	1.0	isoniazid
inhA	1673808	c.-394A>G	upstream_gene_variant	1.0	ethionamide
inhA	1673808	c.-394A>G	upstream_gene_variant	1.0	isoniazid
inhA	1674471	c.270G>C	synonymous_variant	0.87	ethionamide
inhA	1674471	c.270G>C	synonymous_variant	0.87	isoniazid
inhA	1674474	c.273G>C	synonymous_variant	0.87	ethionamide
inhA	1674474	c.273G>C	synonymous_variant	0.87	isoniazid
inhA	1674486	c.285T>C	synonymous_variant	0.87	ethionamide
inhA	1674486	c.285T>C	synonymous_variant	0.87	isoniazid
inhA	1674502	c.301_303delACCinsTG	frameshift_variant&missense_variant	0.87	ethionamide
inhA	1674502	c.301_303delACCinsTG	frameshift_variant&missense_variant	0.87	isoniazid
inhA	1674507	c.306G>C	synonymous_variant	0.88	ethionamide
inhA	1674507	c.306G>C	synonymous_variant	0.88	isoniazid
inhA	1674513	c.312C>G	synonymous_variant	0.89	ethionamide
inhA	1674513	c.312C>G	synonymous_variant	0.89	isoniazid
inhA	1674534	c.333G>A	synonymous_variant	0.91	ethionamide
inhA	1674534	c.333G>A	synonymous_variant	0.91	isoniazid
inhA	1674542	p.Ala114Glu	missense_variant	0.95	ethionamide
inhA	1674542	p.Ala114Glu	missense_variant	0.95	isoniazid
inhA	1674546	c.345T>C	synonymous_variant	0.95	ethionamide
inhA	1674546	c.345T>C	synonymous_variant	0.95	isoniazid
inhA	1674549	c.348G>C	synonymous_variant	0.95	ethionamide
inhA	1674549	c.348G>C	synonymous_variant	0.95	isoniazid
inhA	1674550	p.Ser117Ala	missense_variant	0.95	ethionamide
inhA	1674550	p.Ser117Ala	missense_variant	0.95	isoniazid
inhA	1674561	c.360C>T	synonymous_variant	0.96	ethionamide
inhA	1674561	c.360C>T	synonymous_variant	0.96	isoniazid
inhA	1674576	c.375T>C	synonymous_variant	0.94	ethionamide
inhA	1674576	c.375T>C	synonymous_variant	0.94	isoniazid
inhA	1674579	c.378G>C	synonymous_variant	0.94	ethionamide
inhA	1674579	c.378G>C	synonymous_variant	0.94	isoniazid
inhA	1674582	c.381T>C	synonymous_variant	0.94	ethionamide
inhA	1674582	c.381T>C	synonymous_variant	0.94	isoniazid
inhA	1674585	c.384T>C	synonymous_variant	0.94	ethionamide
inhA	1674585	c.384T>C	synonymous_variant	0.94	isoniazid
inhA	1674589	p.Met130Leu	missense_variant	0.94	ethionamide
inhA	1674589	p.Met130Leu	missense_variant	0.94	isoniazid
inhA	1674601	p.Leu134Thr	missense_variant	0.94	ethionamide
inhA	1674601	p.Leu134Thr	missense_variant	0.94	isoniazid
inhA	1674636	c.435C>G	synonymous_variant	1.0	ethionamide
inhA	1674636	c.435C>G	synonymous_variant	1.0	isoniazid
inhA	1674654	c.453G>C	synonymous_variant	1.0	ethionamide
inhA	1674654	c.453G>C	synonymous_variant	1.0	isoniazid
inhA	1674656	p.Ser152Thr	missense_variant	1.0	ethionamide
inhA	1674656	p.Ser152Thr	missense_variant	1.0	isoniazid
inhA	1674669	c.468G>C	synonymous_variant	1.0	ethionamide
inhA	1674669	c.468G>C	synonymous_variant	1.0	isoniazid
inhA	1674672	c.471C>G	synonymous_variant	1.0	ethionamide
inhA	1674672	c.471C>G	synonymous_variant	1.0	isoniazid
inhA	1674690	c.489C>G	synonymous_variant	1.0	ethionamide
inhA	1674690	c.489C>G	synonymous_variant	1.0	isoniazid
inhA	1674703	c.502T>C	synonymous_variant	1.0	ethionamide
inhA	1674703	c.502T>C	synonymous_variant	1.0	isoniazid
inhA	1674711	c.510G>C	synonymous_variant	1.0	ethionamide
inhA	1674711	c.510G>C	synonymous_variant	1.0	isoniazid
inhA	1674718	c.517A>C	synonymous_variant	1.0	ethionamide
inhA	1674718	c.517A>C	synonymous_variant	1.0	isoniazid
inhA	1674726	c.525G>C	synonymous_variant	1.0	ethionamide
inhA	1674726	c.525G>C	synonymous_variant	1.0	isoniazid
inhA	1674737	p.Ala179Val	missense_variant	1.0	ethionamide
inhA	1674737	p.Ala179Val	missense_variant	1.0	isoniazid
inhA	1674741	c.540C>A	synonymous_variant	1.0	ethionamide
inhA	1674741	c.540C>A	synonymous_variant	1.0	isoniazid
inhA	1674742	p.Lys181Pro	missense_variant	1.0	ethionamide
inhA	1674742	p.Lys181Pro	missense_variant	1.0	isoniazid
inhA	1674745	p.Tyr182His	missense_variant	1.0	ethionamide	Uncertain significance
inhA	1674745	p.Tyr182His	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674750	c.549T>G	synonymous_variant	1.0	ethionamide
inhA	1674750	c.549T>G	synonymous_variant	1.0	isoniazid
inhA	1674771	c.570C>G	synonymous_variant	1.0	ethionamide
inhA	1674771	c.570C>G	synonymous_variant	1.0	isoniazid
inhA	1674780	c.579T>G	synonymous_variant	1.0	ethionamide
inhA	1674780	c.579T>G	synonymous_variant	1.0	isoniazid
inhA	1674786	c.585G>C	synonymous_variant	1.0	ethionamide
inhA	1674786	c.585G>C	synonymous_variant	1.0	isoniazid
inhA	1674801	c.600T>C	synonymous_variant	1.0	ethionamide
inhA	1674801	c.600T>C	synonymous_variant	1.0	isoniazid
inhA	1674804	c.603G>C	synonymous_variant	1.0	ethionamide	Not assoc w R - Interim
inhA	1674804	c.603G>C	synonymous_variant	1.0	isoniazid
inhA	1674810	c.609C>G	synonymous_variant	1.0	ethionamide
inhA	1674810	c.609C>G	synonymous_variant	1.0	isoniazid
inhA	1674813	c.612C>G	synonymous_variant	1.0	ethionamide
inhA	1674813	c.612C>G	synonymous_variant	1.0	isoniazid
inhA	1674816	c.615T>A	synonymous_variant	1.0	ethionamide
inhA	1674816	c.615T>A	synonymous_variant	1.0	isoniazid
inhA	1674822	c.621C>G	synonymous_variant	1.0	ethionamide
inhA	1674822	c.621C>G	synonymous_variant	1.0	isoniazid
inhA	1674825	c.624C>T	synonymous_variant	1.0	ethionamide
inhA	1674825	c.624C>T	synonymous_variant	1.0	isoniazid	Not assoc w R - Interim
inhA	1674828	c.627G>A	synonymous_variant	1.0	ethionamide
inhA	1674828	c.627G>A	synonymous_variant	1.0	isoniazid
inhA	1674839	p.Ala213Glu	missense_variant	1.0	ethionamide
inhA	1674839	p.Ala213Glu	missense_variant	1.0	isoniazid
inhA	1674846	p.Ile215Met	missense_variant	1.0	ethionamide
inhA	1674846	p.Ile215Met	missense_variant	1.0	isoniazid
inhA	1674848	p.Gln216Arg	missense_variant	1.0	ethionamide
inhA	1674848	p.Gln216Arg	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674870	c.669T>C	synonymous_variant	1.0	ethionamide
inhA	1674870	c.669T>C	synonymous_variant	1.0	isoniazid
inhA	1674879	c.678T>G	synonymous_variant	1.0	ethionamide
inhA	1674879	c.678T>G	synonymous_variant	1.0	isoniazid
inhA	1674882	c.681G>C	synonymous_variant	1.0	ethionamide
inhA	1674882	c.681G>C	synonymous_variant	1.0	isoniazid
inhA	1674883	p.Ile228Val	missense_variant	1.0	ethionamide	Uncertain significance
inhA	1674883	p.Ile228Val	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674892	p.Asn231Asp	missense_variant	1.0	ethionamide	Uncertain significance
inhA	1674892	p.Asn231Asp	missense_variant	1.0	isoniazid	Uncertain significance
inhA	1674904	p.Ala235Pro	missense_variant	0.96	ethionamide
inhA	1674904	p.Ala235Pro	missense_variant	0.96	isoniazid
rpsA	1833537	c.-5_-1delACAATinsCCAC	upstream_gene_variant	0.83	pyrazinamide
rpsA	1833547	c.6G>A	synonymous_variant	0.87	pyrazinamide
rpsA	1833554	p.Thr5Ser	missense_variant	0.88	pyrazinamide
rpsA	1833568	c.27G>C	synonymous_variant	0.92	pyrazinamide	Not assoc w R - Interim
rpsA	1833589	c.48A>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833595	c.54T>G	synonymous_variant	0.97	pyrazinamide
rpsA	1833616	c.75A>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833619	c.78A>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833628	c.87G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1833634	c.93G>A	synonymous_variant	0.98	pyrazinamide
rpsA	1833664	c.123C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833667	c.126C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833676	c.135A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833679	c.138G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833685	c.144G>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833691	c.150G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1833694	c.153G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833697	c.156C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833709	c.168C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833727	c.186G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833733	c.192C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833734	p.Ala65Ser	missense_variant	1.0	pyrazinamide
rpsA	1833745	c.204G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833787	c.246C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833790	c.249T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833793	c.252C>T	synonymous_variant	1.0	pyrazinamide
rpsA	1833811	c.270G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833832	c.291G>A	synonymous_variant	1.0	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833862	c.321G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833892	c.351G>A	synonymous_variant	0.97	pyrazinamide
rpsA	1833894	p.Ala118Glu	missense_variant	0.97	pyrazinamide
rpsA	1833901	c.360G>A	synonymous_variant	0.97	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	0.96	pyrazinamide
rpsA	1833949	c.408T>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833970	c.429G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1833979	c.438T>C	synonymous_variant	0.96	pyrazinamide
rpsA	1833991	c.450C>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834000	c.459G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834012	c.471G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1834015	c.474G>C	synonymous_variant	0.97	pyrazinamide
rpsA	1834021	c.480C>T	synonymous_variant	0.97	pyrazinamide
rpsA	1834030	c.489C>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834093	c.552G>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834094	c.553C>T	synonymous_variant	0.94	pyrazinamide
rpsA	1834097	c.556_557delTCinsAG	synonymous_variant	0.94	pyrazinamide
rpsA	1834102	c.561T>C	synonymous_variant	0.94	pyrazinamide
rpsA	1834105	c.564C>T	synonymous_variant	0.95	pyrazinamide
rpsA	1834222	c.681T>C	synonymous_variant	0.85	pyrazinamide
rpsA	1834234	c.693G>T	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
rpsA	1834240	c.699T>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834249	c.708T>C	synonymous_variant	0.9	pyrazinamide
rpsA	1834261	c.720A>G	synonymous_variant	0.89	pyrazinamide	Not assoc w R - Interim
rpsA	1834264	c.723G>C	synonymous_variant	0.89	pyrazinamide
rpsA	1834282	c.741C>T	synonymous_variant	0.94	pyrazinamide
rpsA	1834303	c.762T>G	synonymous_variant	0.95	pyrazinamide
rpsA	1834306	c.765T>C	synonymous_variant	0.95	pyrazinamide
rpsA	1834348	c.807T>C	synonymous_variant	0.97	pyrazinamide	Not assoc w R - Interim
rpsA	1834366	c.825A>G	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
rpsA	1834369	c.828C>G	synonymous_variant	0.99	pyrazinamide
rpsA	1834378	c.837T>C	synonymous_variant	0.99	pyrazinamide	Not assoc w R - Interim
rpsA	1834387	c.846C>T	synonymous_variant	0.99	pyrazinamide
rpsA	1834390	c.849G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834396	c.855G>C	synonymous_variant	0.99	pyrazinamide
rpsA	1834411	c.870T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834423	c.882G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834432	c.891G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834435	c.894G>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834451	c.910T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834456	c.915T>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834465	c.924T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834468	c.927A>G	synonymous_variant	0.98	pyrazinamide
rpsA	1834489	c.948T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834520	p.Ala327Ser	missense_variant	1.0	pyrazinamide
rpsA	1834528	c.987T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1834543	c.1002C>G	synonymous_variant	0.97	pyrazinamide
rpsA	1834546	c.1005T>C	synonymous_variant	0.98	pyrazinamide
rpsA	1834555	c.1014T>G