TB-Profiler result

Run: ERR212034
Summary

Run ID: ERR212034

Sample name:

Date: 2024-03-27T05:32:43.292304

Number of reads: 428419

Percentage reads mapped: 18.25

Median coverage: 5.0

Strain: La1.7;lineage4.9

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.1.2 Indo-Oceanic RD239 0.07
La1.7 M.bovis None 0.1
lineage4 Euro-American None 0.91
lineage4.9 Euro-American (H37Rv-like) None 0.94
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.760_762delTTGinsCA Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.610_612delCTCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1549_1551delCTTinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491542 c.760_762delTTGinsCA frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303540 c.610_612delCTCinsTG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304479 c.1549_1551delCTTinsTG frameshift_variant&missense_variant 0.94 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155108 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 692 c.694delA frameshift_variant 1.0 isoniazid Uncertain significance
dnaA 699 c.699G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 744 c.744C>T synonymous_variant 1.0 isoniazid
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 753 c.753C>T synonymous_variant 1.0 isoniazid
dnaA 759 c.759C>T synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 780 c.780C>G synonymous_variant 1.0 isoniazid
dnaA 783 c.783C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1008 c.1008G>A synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.83 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.83 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.85 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.93 isoniazid
dnaA 1053 c.1053C>T synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 1056 c.1056G>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 0.93 isoniazid
dnaA 1065 c.1065C>T synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 1068 c.1068T>C synonymous_variant 0.93 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.93 isoniazid
dnaA 1077 c.1077A>G synonymous_variant 1.0 isoniazid
dnaA 1080 c.1080C>G synonymous_variant 1.0 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1223 p.Thr408Ile missense_variant 1.0 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>G synonymous_variant 1.0 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 1.0 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 1.0 isoniazid
dnaA 1275 c.1275C>T synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1308 c.1308G>A synonymous_variant 1.0 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>C synonymous_variant 1.0 isoniazid
gyrB 6148 c.909C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6151 c.912C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6187 c.948C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6208 c.969G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6343 c.-959G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6349 c.-953G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6355 c.-947G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6367 c.-935C>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6430 c.-872A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6515 c.-787T>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6523 c.-779G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6526 c.-776T>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6541 c.1302C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6542 c.1303_1305delATCinsCG frameshift_variant&missense_variant 0.91 levofloxacin Uncertain significance
moxifloxacin
gyrB 6550 c.1311A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6551 c.1312_1314delTTGinsCA frameshift_variant&missense_variant 0.91 levofloxacin Uncertain significance
moxifloxacin
gyrA 6556 c.-746C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6592 c.-710C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6679 c.-623G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6685 c.-617C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6787 c.-515G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6817 c.1578G>A synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6850 c.-452C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6877 c.1638G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6931 c.1692A>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrB 6950 c.1711_1713delCTCinsTG frameshift_variant&missense_variant 0.81 levofloxacin Uncertain significance
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 7018 c.-284G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7024 c.-278G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7057 c.-245C>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>T upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7174 c.-128C>T upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7379 c.78C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7430 c.129G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7461 c.160C>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7484 c.183T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7553 c.252C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7574 c.273G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7601 c.300C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>T synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7643 c.342C>A synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7683 c.382_384delAGGinsCC frameshift_variant&missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 7688 c.387C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7758 p.Ile153Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7808 c.507G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7850 c.549C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7853 c.552C>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7859 c.558A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7881 c.580C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7886 c.585T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8252 c.951G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8339 c.1038A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8357 c.1056G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8360 c.1059G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8385 c.1084_1086delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8408 c.1107A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8580 p.Ile427Val missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8597 c.1296C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8609 c.1308G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8633 c.1332C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8637 c.1336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8664 c.1363C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8835 p.Ala512Thr missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8843 c.1542G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8912 c.1611G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9044 c.1743C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9047 c.1746C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9086 c.1785C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9104 c.1803C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9140 c.1839G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9204 p.Ser635Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9341 c.2040C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9365 p.Glu688Asp missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 9369 c.2068C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9389 c.2088C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9421 p.Ile707Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9449 c.2148C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9455 c.2154T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9464 c.2163C>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 490818 c.36C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>G synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490839 c.57G>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490848 c.66A>G synonymous_variant 0.88 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490851 c.69A>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>A synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Lys missense_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491154 c.372G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491163 c.381G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491184 c.402A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491250 c.468G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491256 c.474G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491259 c.477T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491289 c.507C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491295 c.513C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491316 c.534C>T synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491319 c.537G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 491331 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491343 c.561C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491349 c.567T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491355 c.573C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491478 c.696G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491490 c.708C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491496 c.714C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491499 c.717G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491500 p.Glu240Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491523 c.741G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491595 c.813C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491601 c.819T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491616 c.834A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491628 c.846G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 575659 c.312A>T synonymous_variant 0.93 ethionamide
isoniazid
mshA 575665 c.318G>T synonymous_variant 0.94 ethionamide
isoniazid Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575701 c.354G>A synonymous_variant 0.93 ethionamide
isoniazid
mshA 575704 c.357T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 0.86 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575713 c.366G>A synonymous_variant 0.91 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.92 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575749 c.402C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.92 ethionamide
isoniazid
mshA 575772 p.Val142Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575812 c.465C>T synonymous_variant 0.97 ethionamide
isoniazid
mshA 575818 c.471G>C synonymous_variant 0.97 ethionamide
isoniazid
mshA 575821 c.474G>C synonymous_variant 0.96 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.96 ethionamide
isoniazid
mshA 575837 c.490C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575860 c.513G>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575875 c.528C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575923 c.576C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575925 p.Gly193Ala missense_variant 0.92 ethionamide
isoniazid
mshA 575929 c.582C>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 575939 c.592C>T synonymous_variant 0.92 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575947 c.600G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575953 c.606G>C synonymous_variant 0.92 ethionamide
isoniazid
ccsA 620619 c.729G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620647 p.Glu253Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620658 c.768C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620670 c.780C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620692 c.802_804delTCCinsGT frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620727 c.837G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620730 c.840C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620734 c.844C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620758 c.868_870delCGCinsAA frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620802 c.912C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620808 c.918T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620832 c.942C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620847 c.957G>A synonymous_variant 0.94 capreomycin
amikacin
kanamycin
Rv0565c 657187 p.His95Arg missense_variant 1.0 ethionamide
Rv0565c 657189 c.282C>A synonymous_variant 1.0 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 1.0 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 1.0 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657210 c.261C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657220 p.Ala84Val missense_variant 1.0 ethionamide
Rv0565c 657231 c.238_240delATCinsGT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
Rv0565c 657264 c.207T>C synonymous_variant 1.0 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 1.0 ethionamide
Rv0565c 657272 c.199C>T synonymous_variant 1.0 ethionamide
Rv0565c 657273 c.198G>C synonymous_variant 1.0 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657611 c.-141C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657629 c.-159G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657650 c.-180G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657662 c.-192C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657683 c.-213C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657730 c.-260A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731747 c.-183T>C upstream_gene_variant 0.92 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 1.0 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 0.95 isoniazid
hadA 731768 c.-162G>A upstream_gene_variant 0.97 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.97 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 0.97 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 731861 c.-69G>C upstream_gene_variant 1.0 isoniazid
nusG 734073 c.-181_-179delGTTinsAC upstream_gene_variant 0.92 rifampicin
nusG 734082 c.-172A>C upstream_gene_variant 0.85 rifampicin
nusG 734087 c.-167G>C upstream_gene_variant 0.85 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 0.85 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.85 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.85 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.85 rifampicin
nusG 734118 c.-136_-134delCTTinsAG upstream_gene_variant 0.92 rifampicin
nusG 734135 c.-119G>A upstream_gene_variant 0.9 rifampicin
nusG 734442 c.189G>A synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734466 c.213G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734614 c.361_363delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.95 rifampicin
nusG 734637 c.384G>C synonymous_variant 1.0 rifampicin
nusG 734643 c.390G>C synonymous_variant 1.0 rifampicin
nusG 734652 c.399T>C synonymous_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>C synonymous_variant 1.0 rifampicin
nusG 734832 c.579C>G synonymous_variant 1.0 rifampicin
nusG 734844 c.591G>A synonymous_variant 1.0 rifampicin
nusG 734847 c.594T>C synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>G synonymous_variant 1.0 rifampicin
nusG 734863 p.Thr204Ser missense_variant 1.0 rifampicin
nusG 734889 c.636G>A synonymous_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
rpoB 759635 c.-172C>T upstream_gene_variant 0.95 rifampicin
rpoB 759643 c.-164T>C upstream_gene_variant 0.95 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.95 rifampicin Uncertain significance
rpoB 759655 c.-152_-150delCAGinsA upstream_gene_variant 0.94 rifampicin
rpoB 759659 c.-148T>C upstream_gene_variant 0.94 rifampicin
rpoB 759661 c.-146G>C upstream_gene_variant 0.94 rifampicin
rpoB 759662 c.-145C>T upstream_gene_variant 0.94 rifampicin
rpoB 759672 c.-135G>A upstream_gene_variant 0.89 rifampicin
rpoB 759674 c.-133T>C upstream_gene_variant 0.89 rifampicin
rpoB 759678 c.-129T>C upstream_gene_variant 0.94 rifampicin
rpoB 759706 c.-101T>C upstream_gene_variant 0.92 rifampicin
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760148 c.342C>T synonymous_variant 1.0 rifampicin
rpoB 760163 c.357G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>A synonymous_variant 0.98 rifampicin
rpoB 760253 c.447T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>G synonymous_variant 1.0 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 0.97 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.93 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.96 rifampicin
rpoB 760357 p.Thr184Ser missense_variant 0.96 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.96 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 760388 c.582C>T synonymous_variant 0.95 rifampicin
rpoB 760389 c.583_585delAGCinsTCG synonymous_variant 0.95 rifampicin
rpoB 760394 c.588C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760454 c.648C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760527 p.Gln241Ala missense_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>T synonymous_variant 1.0 rifampicin
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760608 c.802C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760697 c.891G>A synonymous_variant 1.0 rifampicin
rpoB 760718 c.912C>A synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.91 rifampicin
rpoB 760841 c.1035T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Ala missense_variant 0.95 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760874 c.1068G>A synonymous_variant 0.98 rifampicin
rpoB 760916 c.1110C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>G synonymous_variant 0.98 rifampicin
rpoB 760922 c.1116G>T synonymous_variant 0.98 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.98 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761006 c.1200C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 1.0 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761192 c.1386C>T synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761217 c.1411_1413delCCGinsTC frameshift_variant&missense_variant 0.69 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>G synonymous_variant 1.0 rifampicin
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761354 c.1548C>T synonymous_variant 0.96 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.96 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.96 rifampicin
rpoB 761402 c.1596C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761408 c.1602G>C synonymous_variant 0.94 rifampicin
rpoB 761411 c.1605G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761414 c.1608A>C synonymous_variant 0.94 rifampicin
rpoB 761423 c.1617T>C synonymous_variant 0.88 rifampicin
rpoB 761483 c.1677G>C synonymous_variant 0.78 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.78 rifampicin
rpoB 761501 c.1695G>C synonymous_variant 0.8 rifampicin
rpoB 761502 p.Pro566Ser missense_variant 0.8 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.84 rifampicin
rpoB 761537 c.1731C>A synonymous_variant 0.9 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.97 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.97 rifampicin
rpoB 761615 c.1809A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.96 rifampicin
rpoB 761655 p.Ala617Arg missense_variant 0.96 rifampicin
rpoB 761672 c.1866C>G synonymous_variant 0.88 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 0.92 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.92 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 0.95 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 0.95 rifampicin
rpoB 761727 p.Ser641Gly missense_variant 0.95 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761750 c.1944G>C synonymous_variant 0.97 rifampicin
rpoB 761765 c.1959T>G synonymous_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 1.0 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761870 c.2064C>T synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>G synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761903 c.2097T>A synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761931 c.2125C>T synonymous_variant 1.0 rifampicin
rpoB 761951 c.2145G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.97 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.97 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762027 c.2221_2223delCTCinsTG frameshift_variant&missense_variant 0.96 rifampicin
rpoB 762038 c.2232C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762056 c.2250G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762068 c.2262C>T synonymous_variant 0.92 rifampicin
rpoB 762083 c.2277T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>T synonymous_variant 0.96 rifampicin
rpoB 762098 c.2292C>G synonymous_variant 0.95 rifampicin
rpoB 762101 c.2295C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.96 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.97 rifampicin
rpoB 762138 c.2332C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762161 c.2355C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762297 c.2491C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 0.97 rifampicin
rpoC 762395 c.-975G>A upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762467 c.-903C>T upstream_gene_variant 1.0 rifampicin
rpoB 762485 c.2679G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762486 p.Pro894Ala missense_variant 0.97 rifampicin
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.97 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>G upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 1.0 rifampicin
rpoC 762590 c.-780C>G upstream_gene_variant 1.0 rifampicin
rpoB 762593 c.2787C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762608 c.-762C>G upstream_gene_variant 1.0 rifampicin
rpoC 762728 c.-642C>T upstream_gene_variant 1.0 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 1.0 rifampicin
rpoC 762741 c.-629C>T upstream_gene_variant 1.0 rifampicin
rpoC 762749 c.-621C>G upstream_gene_variant 1.0 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762758 c.-612G>C upstream_gene_variant 1.0 rifampicin
rpoB 762760 p.Cys985Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762785 c.-585C>T upstream_gene_variant 1.0 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762899 c.3093G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 0.95 rifampicin
rpoB 762995 c.3189G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.97 rifampicin
rpoC 763079 c.-291C>G upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763094 c.3288G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>A upstream_gene_variant 1.0 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763157 c.3351G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763158 c.-212C>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763220 c.-150G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.95 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 0.95 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.91 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.9 rifampicin
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.97 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 0.97 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.97 rifampicin
rpoC 763765 c.396T>C synonymous_variant 1.0 rifampicin
rpoC 763768 c.399C>G synonymous_variant 1.0 rifampicin
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763783 c.414G>C synonymous_variant 1.0 rifampicin
rpoC 763796 p.Met143Leu missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763804 c.435C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763849 c.480G>A synonymous_variant 1.0 rifampicin
rpoC 763852 c.483C>G synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 0.95 rifampicin
rpoC 763906 c.537C>T synonymous_variant 1.0 rifampicin
rpoC 763936 c.567C>G synonymous_variant 0.97 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.97 rifampicin
rpoC 763951 c.582G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>G synonymous_variant 0.97 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.98 rifampicin
rpoC 764002 c.633C>G synonymous_variant 0.98 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>G synonymous_variant 0.98 rifampicin
rpoC 764167 c.798G>A synonymous_variant 0.98 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 0.97 rifampicin
rpoC 764195 p.Ser276Ala missense_variant 0.97 rifampicin
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>T synonymous_variant 1.0 rifampicin
rpoC 764248 c.879C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764255 c.886C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764260 c.891G>A synonymous_variant 0.92 rifampicin
rpoC 764266 c.897T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764272 c.903G>A synonymous_variant 0.93 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764284 c.915G>C synonymous_variant 0.93 rifampicin
rpoC 764285 p.Gly306Thr missense_variant 0.93 rifampicin
rpoC 764317 c.948C>G synonymous_variant 0.95 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764383 c.1014C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.94 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.94 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.94 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.94 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.93 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764542 c.1173C>A synonymous_variant 0.93 rifampicin
rpoC 764548 c.1179G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764656 c.1287C>G synonymous_variant 0.95 rifampicin
rpoC 764668 c.1299C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 0.96 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.96 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.96 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764851 c.1482C>T synonymous_variant 1.0 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.97 rifampicin
rpoC 764878 c.1509C>T synonymous_variant 0.97 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764896 c.1527C>T synonymous_variant 0.97 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764932 c.1563C>G synonymous_variant 0.94 rifampicin
rpoC 764968 c.1599T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764983 c.1614T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.92 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>A synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765259 c.1890G>C synonymous_variant 1.0 rifampicin
rpoC 765281 c.1912_1914delACCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765292 c.1923G>C synonymous_variant 1.0 rifampicin
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>C synonymous_variant 1.0 rifampicin
rpoC 765350 c.1981_1983delGCGinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765361 c.1992C>G synonymous_variant 1.0 rifampicin
rpoC 765404 c.2035_2037delCTGinsGC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 765409 c.2040T>A synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.97 rifampicin
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765496 c.2127C>G synonymous_variant 0.97 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.98 rifampicin
rpoC 765548 c.2179_2180delAGinsTC synonymous_variant 0.96 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.97 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765590 p.Arg741Gly missense_variant 0.97 rifampicin
rpoC 765596 p.Lys743Gln missense_variant 0.96 rifampicin
rpoC 765611 p.His748Ala missense_variant 1.0 rifampicin
rpoC 765619 c.2250G>A synonymous_variant 1.0 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765740 p.Glu791Gln missense_variant 0.95 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.93 rifampicin
rpoC 765787 c.2418C>T synonymous_variant 0.94 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.94 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.94 rifampicin
rpoC 765805 c.2436C>T synonymous_variant 0.95 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>T synonymous_variant 0.95 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>G synonymous_variant 0.96 rifampicin
rpoC 765871 c.2502T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 0.96 rifampicin Uncertain significance
rpoC 765883 c.2514C>G synonymous_variant 0.94 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.96 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>G synonymous_variant 0.95 rifampicin
rpoC 765940 c.2571A>G synonymous_variant 0.95 rifampicin
rpoC 765967 c.2598C>G synonymous_variant 1.0 rifampicin
rpoC 765973 c.2604C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765985 c.2616C>T synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766018 c.2649C>T synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766034 p.His889Ala missense_variant 1.0 rifampicin
rpoC 766043 p.Gln892Gly missense_variant 1.0 rifampicin
rpoC 766061 p.Val898Thr missense_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766113 p.Tyr915Phe missense_variant 1.0 rifampicin
rpoC 766120 c.2751A>G synonymous_variant 1.0 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>C synonymous_variant 1.0 rifampicin
rpoC 766138 c.2769G>C synonymous_variant 1.0 rifampicin
rpoC 766141 c.2772C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766148 p.Thr927Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766381 c.3012C>G synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766546 p.Glu1059Asp missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766568 p.Val1067Ile missense_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766582 c.3213C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766618 c.3249G>C synonymous_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 1.0 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.97 rifampicin
rpoC 766652 p.Ser1095Thr missense_variant 0.97 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.97 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 0.97 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 0.97 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 0.97 rifampicin
rpoC 766678 c.3309C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766687 c.3318G>A synonymous_variant 0.97 rifampicin
rpoC 766688 p.Val1107Leu missense_variant 0.97 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.97 rifampicin
rpoC 766723 c.3354G>C synonymous_variant 0.97 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.96 rifampicin
rpoC 766749 p.Pro1127Gln missense_variant 0.96 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766820 p.Asp1151Asn missense_variant 1.0 rifampicin
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766871 p.Ile1168Val missense_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766920 p.Ala1184Gly missense_variant 1.0 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767035 c.3666G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767146 c.3777G>C synonymous_variant 1.0 rifampicin
rpoC 767152 c.3783T>G synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767186 p.Gln1273Glu missense_variant 1.0 rifampicin
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767224 c.3855C>T synonymous_variant 1.0 rifampicin
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>A synonymous_variant 1.0 rifampicin
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781592 c.33T>G synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 c.49_51delAGTinsGC frameshift_variant&missense_variant 1.0 streptomycin Uncertain significance
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781679 c.120C>G synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>G synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.97 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781733 c.174G>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781779 c.220C>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781841 c.282C>G synonymous_variant 1.0 streptomycin
rpsL 781859 c.300T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rplC 800244 c.-565A>G upstream_gene_variant 0.8 linezolid
rplC 800252 c.-557C>A upstream_gene_variant 0.9 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 0.82 linezolid
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800531 c.-278T>C upstream_gene_variant 1.0 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800558 c.-251G>A upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>G upstream_gene_variant 0.96 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 0.95 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 0.93 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 0.92 linezolid
rplC 800600 c.-209G>T upstream_gene_variant 0.92 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.92 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.9 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 0.9 linezolid
rplC 800657 c.-152G>A upstream_gene_variant 0.9 linezolid
rplC 800663 c.-146G>A upstream_gene_variant 0.9 linezolid
rplC 800666 c.-143C>T upstream_gene_variant 0.9 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 0.95 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.91 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.91 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.92 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.92 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.92 linezolid
rplC 800726 c.-83G>A upstream_gene_variant 0.92 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.9 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.89 linezolid
rplC 800760 c.-49_-47delCTTinsTG upstream_gene_variant 0.89 linezolid
rplC 800765 c.-44G>C upstream_gene_variant 0.91 linezolid
rplC 800798 c.-11_-6delTGGACAinsCTGC upstream_gene_variant 0.93 linezolid
rplC 800814 c.6A>G synonymous_variant 0.93 linezolid
rplC 800815 c.7C>A synonymous_variant 0.93 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800832 c.24T>C synonymous_variant 1.0 linezolid
rplC 800841 c.33G>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800907 c.99C>G synonymous_variant 1.0 linezolid
rplC 801168 c.360C>T synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801183 c.375C>A synonymous_variant 1.0 linezolid
rplC 801186 c.378C>G synonymous_variant 1.0 linezolid
rplC 801210 c.402T>G synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801231 c.423C>T synonymous_variant 1.0 linezolid
rplC 801243 c.435C>T synonymous_variant 1.0 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801300 c.492C>T synonymous_variant 0.95 linezolid
rplC 801312 c.504G>A synonymous_variant 0.95 linezolid
rplC 801324 c.516T>C synonymous_variant 0.95 linezolid
rplC 801337 p.Val177Thr missense_variant 0.94 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.94 linezolid
rplC 801348 c.540T>G synonymous_variant 0.96 linezolid
rplC 801357 c.549T>C synonymous_variant 0.96 linezolid
rplC 801393 c.585G>A synonymous_variant 1.0 linezolid
rplC 801399 c.591G>C synonymous_variant 1.0 linezolid
rplC 801402 c.594T>G synonymous_variant 1.0 linezolid
rplC 801411 c.603C>A synonymous_variant 1.0 linezolid
rplC 801420 c.612A>G synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801438 c.630T>C synonymous_variant 1.0 linezolid
fbiC 1303497 c.567G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303501 c.571C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303594 c.664C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1303602 c.672A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303695 c.765T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303698 c.768C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303731 c.801A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303752 c.822A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303758 c.828G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303764 c.834C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303794 c.864A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303800 c.870G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304163 c.1233G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304166 c.1236A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304169 c.1239T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304174 p.Val415Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304425 c.1495C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304436 c.1506G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304442 c.1512T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304444 p.Ala505Asp missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304465 p.Gly512Ala missense_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304478 c.1548G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304487 c.1557C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304493 c.1563C>T synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304706 c.1776C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304730 c.1800C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304739 c.1809C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304798 p.Ala623Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304800 c.1870C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304983 c.2053C>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304988 c.2058G>T synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305018 c.2088C>T synonymous_variant 0.92 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305021 c.2091C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305270 c.2340C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364667 c.255T>C synonymous_variant 1.0 pyrazinamide
sigE 1364673 c.261G>C synonymous_variant 1.0 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364697 c.285G>C synonymous_variant 1.0 pyrazinamide
sigE 1364703 c.291G>A synonymous_variant 1.0 pyrazinamide
sigE 1364704 c.292C>T synonymous_variant 1.0 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.97 pyrazinamide
sigE 1364748 c.336G>C synonymous_variant 0.97 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.96 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.96 pyrazinamide
sigE 1364772 c.360G>C synonymous_variant 0.95 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.95 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.94 pyrazinamide
sigE 1364802 c.390C>G synonymous_variant 0.92 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.91 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 0.9 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.9 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 0.9 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 0.9 pyrazinamide
sigE 1364872 p.Ile154Val missense_variant 0.91 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
sigE 1364895 p.Glu161Asp missense_variant 0.92 pyrazinamide
sigE 1364910 c.498G>C synonymous_variant 0.92 pyrazinamide
sigE 1364913 c.501C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
sigE 1364919 c.507T>C synonymous_variant 0.92 pyrazinamide
atpE 1461101 c.57T>G synonymous_variant 0.92 bedaquiline
atpE 1461107 c.63C>G synonymous_variant 0.85 bedaquiline
atpE 1461134 c.90C>T synonymous_variant 0.94 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.94 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.94 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.94 bedaquiline Uncertain significance
atpE 1461170 c.126A>G synonymous_variant 0.92 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471928 n.83T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471930 n.85_89delGGAGAinsTTGCAGGG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471996 n.151C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472027 n.182C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472045 n.200T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472056 n.211_212delGCinsT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.452_453insCTGCCC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472300 n.455C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472301 n.456C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472305 n.461_466delTCTCTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.469_470delAT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473289 n.1444T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473290 n.1445_1446insAA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrl 1473668 n.11C>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473670 n.13A>T non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473701 n.44A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473743 n.86C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473782 n.125A>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1473792 n.135C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473793 n.136G>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473877 n.220G>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474286 n.629_630delCTinsTCCTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474293 n.637_646delCCTCTCCGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474350 n.693G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474452 n.795C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474710 n.1053T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474715 n.1058T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475015 n.1358C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1475029 n.1372T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475202 n.1545G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475208 n.1551_1552insA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475212 n.1555A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475217 n.1560T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475430 n.1773_1774delTTinsA non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475526 n.1869C>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475539 n.1882A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475556 n.1899A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475635 n.1978G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475707 n.2050T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475762 n.2105_2106delGCinsTTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475989 n.2332T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476252 n.2595T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476691 n.3034T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
inhA 1673499 c.-703T>G upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673502 c.-700C>G upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673505 c.-697A>C upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673548 p.Ala37Ser missense_variant 0.94 ethionamide
isoniazid
inhA 1673565 c.-637G>A upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673574 c.-628C>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.91 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.93 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.93 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673616 c.-586A>G upstream_gene_variant 0.96 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.9 ethionamide
isoniazid
inhA 1673643 c.-559C>G upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.93 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673709 c.-493C>G upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1673712 c.-490A>G upstream_gene_variant 0.98 ethionamide
isoniazid
inhA 1673713 c.-489T>G upstream_gene_variant 0.98 ethionamide
isoniazid Uncertain significance
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673755 p.Glu106Gln missense_variant 1.0 ethionamide
isoniazid
fabG1 1673767 p.Asn110Asp missense_variant 1.0 ethionamide
isoniazid
inhA 1673784 c.-418G>A upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673808 c.-394A>G upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673825 c.387_390delCAAC frameshift_variant 0.87 ethionamide
isoniazid
fabG1 1673832 c.394_395insCGGT frameshift_variant 0.87 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673856 c.-346T>G upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673870 p.Ser144Thr missense_variant 0.91 ethionamide
isoniazid
inhA 1673895 c.-307C>T upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673901 c.-301A>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673916 c.-286A>T upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673922 p.Ile161Met missense_variant 0.94 ethionamide
isoniazid
inhA 1673925 c.-277C>T upstream_gene_variant 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673946 c.-256C>G upstream_gene_variant 0.95 ethionamide
isoniazid
fabG1 1673950 p.Leu171Met missense_variant 0.95 ethionamide
isoniazid
inhA 1673961 c.-241A>C upstream_gene_variant 0.98 ethionamide
isoniazid
fabG1 1673995 p.Ile186Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674016 c.-186G>A upstream_gene_variant 0.95 ethionamide
isoniazid Uncertain significance
inhA 1674021 c.-181G>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 0.95 ethionamide
isoniazid
fabG1 1674037 p.Gln200Glu missense_variant 0.94 ethionamide
isoniazid
inhA 1674045 c.-157G>A upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 0.94 ethionamide
isoniazid
inhA 1674090 c.-112C>G upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1674114 c.-88T>G upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1674117 c.-85C>G upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1674129 c.-73C>T upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1674517 p.Asn106His missense_variant 0.95 ethionamide
isoniazid
inhA 1674531 c.330C>T synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.96 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674597 c.396G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674617 p.Asn139Ser missense_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1674619 p.Pro140Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674630 c.429C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674639 c.438C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502_504delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674732 c.531C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674743 p.Lys181Arg missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674858 c.657G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674861 c.660G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674882 c.681G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674888 c.687C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674903 c.702T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674904 p.Ala235Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674915 c.714C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674934 p.Leu245Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674942 c.741T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674945 p.Asp248Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674957 c.756G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674960 c.759C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674984 c.783C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1675005 c.804G>A synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833289 c.-253G>T upstream_gene_variant 1.0 pyrazinamide
rpsA 1833568 c.27G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833667 c.126C>A synonymous_variant 0.97 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833688 c.147C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833695 c.154_156delCTCinsTG frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>G synonymous_variant 0.94 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.94 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.94 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.95 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833748 c.207C>G synonymous_variant 0.95 pyrazinamide
rpsA 1833778 c.237C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833781 c.240T>G synonymous_variant 0.96 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833794 p.Glu85Lys missense_variant 0.96 pyrazinamide
rpsA 1833799 c.258C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833805 c.264C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833886 c.345C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833898 c.357C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833901 c.360G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834114 c.573G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834192 c.651C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834219 c.678C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>A synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834282 c.741C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834285 c.744G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834360 c.819G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834495 c.954G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834525 c.984G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834561 c.1020C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834615 c.1074C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.92 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.92 pyrazinamide
ndh 2102047 c.996G>C synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102050 c.993T>G synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102056 c.987G>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102059 c.984T>C synonymous_variant 0.94 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102062 p.Glu327Asp missense_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102065 c.978G>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102068 c.975T>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102077 c.966T>C synonymous_variant 0.94 ethionamide
delamanid
isoniazid
ndh 2102083 c.960G>C synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102104 c.939G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102623 c.420C>T synonymous_variant 0.91 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102638 c.405A>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102668 c.375T>C synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2102680 c.363T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102689 c.354C>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102692 c.349_351delGTCinsAT frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
katG 2155014 c.1098C>T synonymous_variant 0.92 isoniazid
katG 2155017 c.1095G>C synonymous_variant 0.92 isoniazid
katG 2155023 c.1089C>G synonymous_variant 0.94 isoniazid
katG 2155029 c.1083C>G synonymous_variant 0.95 isoniazid
katG 2155050 c.1062C>G synonymous_variant 0.96 isoniazid
katG 2155054 p.Tyr353Phe missense_variant 0.95 isoniazid
katG 2155056 c.1056A>G synonymous_variant 0.95 isoniazid
katG 2155062 c.1050T>C synonymous_variant 0.95 isoniazid
katG 2155065 c.1047C>A synonymous_variant 0.95 isoniazid Not assoc w R - Interim
katG 2155068 c.1044T>C synonymous_variant 0.95 isoniazid
katG 2155071 c.1041T>C synonymous_variant 0.95 isoniazid
katG 2155080 c.1032G>C synonymous_variant 0.95 isoniazid
katG 2155113 c.999C>G synonymous_variant 1.0 isoniazid
katG 2155117 p.Phe332Tyr missense_variant 1.0 isoniazid
katG 2155120 p.Ser331Thr missense_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155661 p.Val151Ile missense_variant 1.0 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155683 c.429G>A synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 c.417C>G synonymous_variant 1.0 isoniazid
kasA 2517965 c.-150C>G upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2517994 c.-121C>A upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 1.0 isoniazid
kasA 2518031 c.-84G>C upstream_gene_variant 1.0 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 1.0 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 1.0 isoniazid
kasA 2518053 c.-62_-60delATTinsCC upstream_gene_variant 1.0 isoniazid
kasA 2518064 c.-51G>A upstream_gene_variant 1.0 isoniazid
kasA 2518156 c.42T>C synonymous_variant 0.92 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.93 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.94 isoniazid
kasA 2518183 c.69G>A synonymous_variant 0.94 isoniazid
kasA 2518186 c.72G>C synonymous_variant 0.94 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.94 isoniazid
kasA 2518195 c.81G>T synonymous_variant 0.94 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.94 isoniazid
kasA 2518223 c.109_111delTTGinsCA frameshift_variant&missense_variant 0.92 isoniazid
kasA 2518462 c.348A>G synonymous_variant 1.0 isoniazid
kasA 2518465 c.351T>C synonymous_variant 1.0 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518475 c.361A>C synonymous_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518483 c.369C>G synonymous_variant 1.0 isoniazid
kasA 2518492 c.378C>T synonymous_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518571 p.Val153Thr missense_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>G synonymous_variant 1.0 isoniazid
kasA 2518582 c.468G>C synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>C synonymous_variant 1.0 isoniazid
kasA 2518621 c.507G>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Ile missense_variant 1.0 isoniazid
kasA 2518696 c.582C>G synonymous_variant 1.0 isoniazid
kasA 2518705 c.591T>C synonymous_variant 0.95 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518723 c.609G>A synonymous_variant 1.0 isoniazid
kasA 2518732 c.618C>G synonymous_variant 1.0 isoniazid
kasA 2518744 c.630C>T synonymous_variant 0.97 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.97 isoniazid
kasA 2518783 c.669T>G synonymous_variant 0.96 isoniazid
kasA 2518786 c.672G>A synonymous_variant 0.96 isoniazid
kasA 2518787 p.Arg225Ala missense_variant 0.96 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.96 isoniazid
kasA 2518795 c.681C>A synonymous_variant 0.96 isoniazid
kasA 2518798 c.684G>T synonymous_variant 0.96 isoniazid
kasA 2518822 c.708C>T synonymous_variant 0.96 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.96 isoniazid
kasA 2518849 c.735G>C synonymous_variant 1.0 isoniazid
kasA 2518853 p.Leu247Val missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518879 c.765A>G synonymous_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
kasA 2518892 p.Lys260Gln missense_variant 1.0 isoniazid
ahpC 2726299 p.Thr36Ser missense_variant 0.81 isoniazid
ahpC 2726303 c.111T>C synonymous_variant 0.88 isoniazid
ahpC 2726307 p.Thr39Ser missense_variant 0.87 isoniazid
ahpC 2726312 c.120T>C synonymous_variant 0.93 isoniazid
ahpC 2726318 p.Glu42Asp missense_variant 0.93 isoniazid
ahpC 2726322 p.Pro44Glu missense_variant 0.92 isoniazid
ahpC 2726348 c.156T>C synonymous_variant 0.86 isoniazid
ahpC 2726357 c.165A>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
ahpC 2726366 c.174G>C synonymous_variant 0.89 isoniazid
ahpC 2726372 c.180G>C synonymous_variant 0.82 isoniazid
ahpC 2726378 c.186T>A synonymous_variant 0.86 isoniazid Not assoc w R
ahpC 2726387 c.195C>T synonymous_variant 0.85 isoniazid
ahpC 2726397 p.Ser69Gly missense_variant 0.82 isoniazid
ahpC 2726402 c.210G>A synonymous_variant 0.82 isoniazid
ahpC 2726408 c.216T>C synonymous_variant 0.82 isoniazid
folC 2746999 c.600T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747002 c.597T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747029 c.570G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747032 c.567A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747070 p.Met177Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747077 c.522G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747083 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747097 p.Val168Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747314 c.285A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747326 c.273G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747335 c.264G>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsCG frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
folC 2747344 c.255G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747349 p.Ala84Ser missense_variant 1.0 para-aminosalicylic_acid
folC 2747350 c.249C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747359 c.240C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747362 c.237G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747368 c.231G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747389 c.210G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747395 c.204T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747407 c.192T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747414 p.Arg62His missense_variant 1.0 para-aminosalicylic_acid
folC 2747416 c.183A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747419 c.180C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747422 c.177G>A synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747428 c.171G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747434 c.165C>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747442 c.157T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747443 c.156G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747455 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782414 p.Asp543Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782428 c.1615C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782432 c.1611G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782441 c.1602G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782444 c.1599G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782454 p.Gly530Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782480 c.1563G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782486 c.1557G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782495 p.Asp516Glu missense_variant 1.0 ethambutol
moxifloxacin Uncertain significance
streptomycin
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782531 c.1512C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782534 c.1509C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782993 c.1050C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783038 c.1003_1005delGCCinsAG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783170 c.873C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783173 c.870C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783182 c.861C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783193 p.Ser284Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783206 c.837G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783221 c.822G>T synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.97 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.97 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783242 p.Thr267Gln missense_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783284 c.759G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783287 c.756C>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783317 c.726G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783347 c.696C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783377 c.666C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783380 c.663C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783413 c.630G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783427 p.Pro206Ala missense_variant 0.91 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783437 c.604_606delCTGinsTA frameshift_variant&synonymous_variant 0.9 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783461 c.582T>C synonymous_variant 0.93 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783476 c.567C>T synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783488 c.555G>A synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783491 c.552C>T synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783680 c.363G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783725 c.318C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783746 c.297G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783757 p.Ile96Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783767 c.276C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783773 c.270A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783779 c.264T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783788 c.255T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783791 c.252C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783803 c.240C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783815 c.228A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 c.222A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783826 c.217C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783853 c.190C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783854 c.189C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783866 c.177C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783872 c.171G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783883 c.160T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783884 c.159T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783917 c.126C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783950 c.93C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996401 c.-338T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996404 p.Ile100Met missense_variant 1.0 capreomycin
Rv2681 2996419 c.-320T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996420 p.Val106Ile missense_variant 1.0 capreomycin
Rv2681 2996440 c.-299G>C upstream_gene_variant 1.0 capreomycin
Rv2681 2996443 c.-296T>C upstream_gene_variant 1.0 capreomycin
Rv2681 2997111 p.Val125Leu missense_variant 0.9 capreomycin
Rv2681 2997116 c.378T>G synonymous_variant 0.9 capreomycin
Rv2681 2997122 c.384A>C synonymous_variant 0.9 capreomycin
Rv2681 2997128 c.390A>C synonymous_variant 0.9 capreomycin
Rv2681 2997130 p.Ala131Asp missense_variant 0.9 capreomycin
Rv2681 2997134 c.396A>G synonymous_variant 0.9 capreomycin
Rv2681 2997149 c.411T>C synonymous_variant 0.9 capreomycin
Rv2752c 3064860 c.1332G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064869 c.1323G>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064872 c.1320T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064877 p.Ser439Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064881 c.1309_1311delAGTinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064887 c.1303_1305delAAAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064890 c.1302C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064895 p.Ala433Ser missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064908 c.1284C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064935 c.1257A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064938 p.Glu418Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064941 c.1249_1251delCAAinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3064947 c.1245A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064950 c.1242C>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064956 c.1236T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064974 c.1218T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064977 c.1215C>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064980 c.1212C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3064998 c.1194A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065013 c.1179G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065265 c.927C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065271 c.921C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065274 c.918C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065292 c.898_900delGTTinsAC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065306 p.Ala296Pro missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065311 p.Thr294Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065313 c.879A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065323 p.Ala290Gly missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065867 c.325T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065885 p.Val103Ile missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065922 c.270T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065947 p.Gly82Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065949 c.243C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065957 c.235T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065972 p.Ile74Val missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066003 c.189C>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin
isoniazid
Rv2752c 3066006 c.186G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066011 c.181C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066012 c.180C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066071 c.121T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066074 c.118C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066084 c.108C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066118 p.Asn25Ser missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066123 c.69C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066135 c.57C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066153 c.37_39delTCCinsAT frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066162 c.30C>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067316 c.630A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067352 c.592_594delATGinsGC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067373 c.573C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067376 c.570G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067391 c.555G>C synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.93 para-aminosalicylic_acid
thyX 3067713 p.Val78Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067715 c.231C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.96 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067763 c.181_183delCTCinsTG frameshift_variant&synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067772 c.174C>T synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 0.98 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067811 c.135G>A synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067820 c.126C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067826 c.120C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyX 3067847 p.Pro33Gln missense_variant 0.96 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 0.95 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 0.95 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067877 c.69G>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067883 c.63C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067886 c.60A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067892 c.52_54delTTGinsGC frameshift_variant&missense_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073881 c.591C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073884 c.588C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073898 p.Ala192Ser missense_variant 1.0 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
ald 3087164 c.345T>C synonymous_variant 1.0 cycloserine
ald 3087179 c.360C>T synonymous_variant 1.0 cycloserine
ald 3087200 c.381A>G synonymous_variant 0.93 cycloserine
ald 3087203 c.384C>G synonymous_variant 0.93 cycloserine
ald 3087209 c.390T>G synonymous_variant 0.93 cycloserine
ald 3087225 p.Val136Ile missense_variant 0.93 cycloserine
ald 3087233 c.414T>G synonymous_variant 0.92 cycloserine
ald 3087236 c.417A>G synonymous_variant 0.92 cycloserine
ald 3087239 c.420C>G synonymous_variant 0.92 cycloserine
ald 3087240 p.Ala141Ser missense_variant 0.92 cycloserine
ald 3087251 c.432T>C synonymous_variant 0.91 cycloserine
lpqB 3623360 c.1551A>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623363 c.1548T>C synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623366 c.1545T>G synonymous_variant 0.9 bedaquiline
rifampicin
lpqB 3623378 c.1531_1533delGCCinsTG frameshift_variant&missense_variant 0.93 bedaquiline
rifampicin Uncertain significance
lpqB 3623381 c.1530C>T synonymous_variant 0.93 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623393 p.Thr506Ser missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623400 p.Val504Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623411 p.Gly500Asp missense_variant 1.0 bedaquiline
rifampicin
lpqB 3623417 c.1494A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623423 c.1488C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623444 c.1467T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623456 c.1455T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623459 c.1452G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623468 c.1443T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623471 c.1440C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623479 c.1432C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623480 c.1431C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623486 c.1425G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623492 c.1419T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3623498 c.1413C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624401 c.510C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624416 c.495G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624419 c.492C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624431 c.480C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624452 c.459T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624455 c.456G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624464 c.447A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624470 c.441T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624563 c.348C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624569 c.342C>T synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624575 c.336T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624609 p.Ala101Ser missense_variant 0.91 bedaquiline
rifampicin
lpqB 3624612 p.Ser100Thr missense_variant 0.95 bedaquiline
rifampicin
lpqB 3624614 c.297A>C synonymous_variant 0.96 bedaquiline
rifampicin
lpqB 3624629 c.282G>C synonymous_variant 0.97 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624650 c.261G>C synonymous_variant 0.95 bedaquiline
rifampicin
lpqB 3624662 c.249C>T synonymous_variant 0.94 bedaquiline
rifampicin
lpqB 3625054 c.-144C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625057 c.-147C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
lpqB 3625069 c.-159T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625102 c.-192A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625111 c.-201G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625117 c.-207T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625134 c.-224T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625135 c.1479A>G synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625138 c.-228C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625141 c.-231T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625168 c.-258G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625177 c.1437C>T synonymous_variant 0.97 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625183 c.-273G>A upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625204 c.-294G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625243 c.-333T>G upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625279 c.-369C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625294 c.-384C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625315 c.-405G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrB 3625325 p.His430Arg missense_variant 0.97 bedaquiline
rifampicin
lpqB 3625327 c.-417A>G upstream_gene_variant 0.97 bedaquiline
rifampicin
lpqB 3625336 c.-426C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625372 c.-462A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625375 c.-465A>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625381 c.-471T>G upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625387 c.-477T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3625607 p.Thr336Ile missense_variant 0.94 bedaquiline
rifampicin Uncertain significance
mtrB 3625623 p.Thr331Ala missense_variant 0.95 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625627 p.Asp329Glu missense_variant 0.96 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 0.96 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 0.97 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625702 c.-792C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625708 c.906C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625711 c.903C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625747 c.867G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.864G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625762 c.852A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625774 c.840G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625806 c.808A>C synonymous_variant 0.94 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625813 c.801C>T synonymous_variant 0.93 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625819 c.795G>A synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625828 c.784_786delGTGinsAC frameshift_variant&missense_variant 0.92 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625837 c.777C>G synonymous_variant 0.91 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625849 c.-939T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625855 c.759G>A synonymous_variant 0.8 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3626353 c.261C>G synonymous_variant 0.91 bedaquiline
rifampicin
mtrB 3626357 p.Thr86Asn missense_variant 0.91 bedaquiline
rifampicin
mtrB 3626377 p.Asp79Glu missense_variant 0.9 bedaquiline
rifampicin
mtrB 3626381 p.Ile78Thr missense_variant 0.9 bedaquiline
rifampicin
mtrB 3626389 c.223_225delAGGinsCC frameshift_variant&missense_variant 0.9 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3626400 p.Ile72Val missense_variant 0.9 bedaquiline
rifampicin
mtrB 3626407 c.207C>G synonymous_variant 0.9 bedaquiline
rifampicin
mtrB 3626410 c.204T>C synonymous_variant 0.9 bedaquiline
rifampicin
mtrB 3626413 c.201T>C synonymous_variant 0.9 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626419 c.195C>G synonymous_variant 0.9 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626705 c.-92G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626708 c.-95G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626711 c.-98T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626729 c.-116G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626765 c.585C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626774 c.574_576delAGGinsCT frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>T upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626852 c.-239G>A upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626861 c.-248C>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrA 3626864 c.484_486delTTGinsCA frameshift_variant&missense_variant 0.96 bedaquiline
rifampicin
mtrA 3626873 c.477C>T synonymous_variant 0.96 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626876 c.-263A>G upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626900 c.-287G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626909 c.441C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626996 c.-383G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627008 c.-395G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627026 c.324G>A synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrA 3627068 c.282T>G synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627071 c.-458G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 0.98 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 0.98 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627119 c.231T>G synonymous_variant 0.97 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627139 c.-526T>C upstream_gene_variant 0.97 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627175 c.175C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.160_162delTTAinsCG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627197 c.-584T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627218 c.-605G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627227 c.-614T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627233 c.-620T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627242 c.108C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627263 c.-650C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627269 c.-656G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627275 c.-662G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627301 c.-688T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627320 c.-707C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627323 c.25_27delTTGinsCC frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
fbiB 3640854 c.-681C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640857 c.-678G>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640866 c.-669T>C upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640872 c.-663C>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640875 c.-660C>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640879 c.337C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiB 3640890 c.-645C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiA 3640902 p.Gln120His missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640911 c.-624C>T upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640914 c.-621C>A upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3640920 c.-615A>G upstream_gene_variant 1.0 clofazimine
pretomanid
delamanid
alr 3840230 c.1191T>G synonymous_variant 0.91 cycloserine
alr 3840236 c.1185A>C synonymous_variant 0.93 cycloserine
alr 3840248 c.1173C>G synonymous_variant 1.0 cycloserine
alr 3840272 c.1147_1149delGTCinsCG frameshift_variant&missense_variant 1.0 cycloserine
alr 3840275 c.1146T>G synonymous_variant 1.0 cycloserine
alr 3840278 c.1143T>C synonymous_variant 1.0 cycloserine
alr 3840293 c.1128T>G synonymous_variant 1.0 cycloserine
alr 3840296 c.1125G>C synonymous_variant 1.0 cycloserine
alr 3840299 c.1122C>G synonymous_variant 1.0 cycloserine
alr 3840305 c.1116T>C synonymous_variant 1.0 cycloserine
alr 3841067 c.352_354delATCinsGT frameshift_variant&missense_variant 1.0 cycloserine
alr 3841091 c.330G>C synonymous_variant 1.0 cycloserine
alr 3841100 c.321A>T synonymous_variant 1.0 cycloserine
alr 3841106 c.315T>C synonymous_variant 1.0 cycloserine
alr 3841112 c.309T>C synonymous_variant 1.0 cycloserine
alr 3841115 c.306T>C synonymous_variant 1.0 cycloserine
alr 3841118 c.303C>T synonymous_variant 1.0 cycloserine
alr 3841121 c.298_300delCTGinsTA frameshift_variant&synonymous_variant 1.0 cycloserine
alr 3841127 c.294A>G synonymous_variant 1.0 cycloserine
rpoA 3877521 c.987C>G synonymous_variant 1.0 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877569 c.937_939delCCGinsGC frameshift_variant&missense_variant 0.92 rifampicin
rpoA 3877572 c.936G>C synonymous_variant 0.95 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877598 c.910C>T synonymous_variant 0.97 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.94 rifampicin
rpoA 3877629 c.879C>G synonymous_variant 0.94 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.97 rifampicin
rpoA 3877677 c.829_831delGCGinsTC frameshift_variant&missense_variant 0.96 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 1.0 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877752 c.756C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877788 c.720G>A synonymous_variant 1.0 rifampicin
rpoA 3877848 c.660C>G synonymous_variant 1.0 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 0.95 rifampicin
rpoA 3877872 c.636C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877878 c.630G>A synonymous_variant 1.0 rifampicin
rpoA 3877884 c.624G>C synonymous_variant 1.0 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.95 rifampicin
rpoA 3877895 p.Arg205Cys missense_variant 1.0 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878019 c.489A>C synonymous_variant 1.0 rifampicin
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878046 c.462T>A synonymous_variant 1.0 rifampicin
rpoA 3878050 p.Arg153Lys missense_variant 1.0 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 1.0 rifampicin
rpoA 3878073 c.435C>T synonymous_variant 1.0 rifampicin
rpoA 3878094 c.414C>T synonymous_variant 1.0 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878124 c.384G>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878199 c.309T>C synonymous_variant 1.0 rifampicin
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878220 c.288C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 1.0 rifampicin
rpoA 3878229 c.279C>G synonymous_variant 1.0 rifampicin
rpoA 3878241 c.267G>A synonymous_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878276 c.232C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>T synonymous_variant 1.0 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878361 c.147G>T synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878388 c.120C>A synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>C synonymous_variant 1.0 rifampicin
rpoA 3878403 c.105C>T synonymous_variant 1.0 rifampicin
rpoA 3878406 c.102G>T synonymous_variant 1.0 rifampicin
rpoA 3878409 c.99C>G synonymous_variant 1.0 rifampicin
rpoA 3878432 c.76C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878451 c.57C>G synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>T synonymous_variant 1.0 rifampicin
rpoA 3879022 c.-515G>T upstream_gene_variant 1.0 rifampicin
rpoA 3879034 c.-528_-527delAGinsGT upstream_gene_variant 0.94 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 0.94 rifampicin
rpoA 3879043 c.-536C>A upstream_gene_variant 0.94 rifampicin
rpoA 3879046 c.-539G>A upstream_gene_variant 0.95 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.97 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.97 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.97 rifampicin
rpoA 3879117 c.-610C>T upstream_gene_variant 0.92 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.92 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.92 rifampicin
rpoA 3879130 c.-623A>G upstream_gene_variant 0.93 rifampicin
rpoA 3879136 c.-629A>G upstream_gene_variant 0.95 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.94 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.94 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.86 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.78 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.85 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.83 rifampicin
ddn 3987028 p.Asn62Ser missense_variant 1.0 delamanid
pretomanid
ddn 3987035 c.192C>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987053 c.210T>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987110 c.267C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987137 c.294T>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987138 p.Gln99Ala missense_variant 1.0 delamanid
pretomanid
ddn 3987143 c.300A>G synonymous_variant 1.0 delamanid Not assoc w R - Interim
pretomanid
ddn 3987155 c.312G>A synonymous_variant 1.0 delamanid
pretomanid
ddn 3987158 c.315A>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987164 c.321G>C synonymous_variant 1.0 delamanid
pretomanid
ddn 3987167 c.324C>T synonymous_variant 1.0 delamanid
pretomanid
ddn 3987170 c.327T>G synonymous_variant 1.0 delamanid
pretomanid
ddn 3987185 c.342G>C synonymous_variant 1.0 delamanid
pretomanid
clpC1 4038239 c.2466T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038248 c.2457C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038255 p.Val817Lys missense_variant 1.0 pyrazinamide
clpC1 4038271 p.Pro812Ala missense_variant 1.0 pyrazinamide
clpC1 4038272 c.2431_2433delGGTinsAC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038308 c.2395_2397delGTGinsAC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038314 c.2391T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038354 p.Gln784Ala missense_variant 0.96 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038368 c.2337T>G synonymous_variant 0.96 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038395 c.2310C>T synonymous_variant 0.95 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.95 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038419 c.2286T>C synonymous_variant 0.88 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.92 pyrazinamide
clpC1 4038482 c.2221_2222delCA frameshift_variant 0.9 pyrazinamide
clpC1 4038488 c.2214_2217delCGCCinsGGAAAA frameshift_variant&missense_variant 0.9 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.94 pyrazinamide
clpC1 4038509 p.Asp732Glu missense_variant 0.94 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.91 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038647 c.2058T>C synonymous_variant 0.9 pyrazinamide
clpC1 4038659 c.2044_2046delTCCinsAA frameshift_variant&stop_gained 0.89 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 0.94 pyrazinamide
clpC1 4038679 p.Pro676Ala missense_variant 0.93 pyrazinamide
clpC1 4038680 c.2025G>A synonymous_variant 0.93 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4038694 p.Ser671Ala missense_variant 0.94 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.91 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 0.91 pyrazinamide
clpC1 4038725 c.1980C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.93 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4038812 c.1893T>C synonymous_variant 0.96 pyrazinamide
clpC1 4038827 c.1878G>A synonymous_variant 0.95 pyrazinamide
clpC1 4038838 c.1867C>T synonymous_variant 0.95 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 0.93 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038890 c.1815G>A synonymous_variant 0.96 pyrazinamide
clpC1 4038896 c.1809C>T synonymous_variant 0.97 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038935 c.1770C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038995 c.1708_1710delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039001 c.1702_1704delAACinsGG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039013 c.1692G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039016 c.1689C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039021 c.1684C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039034 c.1671C>G synonymous_variant 0.95 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039076 c.1629G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039109 c.1596C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039133 c.1572C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039136 c.1569C>T synonymous_variant 0.92 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.92 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.91 pyrazinamide
clpC1 4039163 c.1540_1542delCTGinsAC frameshift_variant&missense_variant 0.94 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 0.96 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.96 pyrazinamide
clpC1 4039186 c.1519C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039190 c.1515C>T synonymous_variant 0.96 pyrazinamide
clpC1 4039196 c.1509G>A synonymous_variant 0.96 pyrazinamide
clpC1 4039199 c.1506C>A synonymous_variant 0.97 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039331 c.1374C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039343 c.1362G>A synonymous_variant 0.92 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 0.92 pyrazinamide
clpC1 4039355 c.1350G>T synonymous_variant 0.92 pyrazinamide
clpC1 4039364 c.1341C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 0.9 pyrazinamide
clpC1 4039430 c.1275T>C synonymous_variant 0.92 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039508 c.1197G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039554 p.Thr384Ser missense_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039566 p.Val380Thr missense_variant 1.0 pyrazinamide
clpC1 4039568 p.Met379Ile missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039574 c.1129_1131delGCGinsTC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039661 c.1044T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039693 c.1012C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>T synonymous_variant 0.95 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039784 c.921C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039799 c.906C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039811 c.894C>G synonymous_variant 0.94 pyrazinamide
clpC1 4039817 c.888A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039820 c.885T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039907 c.798G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039985 c.720G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039994 p.Glu237Asp missense_variant 1.0 pyrazinamide
clpC1 4040010 p.Ala232Asn missense_variant 0.92 pyrazinamide
clpC1 4040012 c.693G>A synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040015 c.690G>A synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040027 c.678C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040051 c.654C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040057 c.648C>T synonymous_variant 0.96 pyrazinamide
clpC1 4040087 c.618G>A synonymous_variant 0.95 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.95 pyrazinamide
clpC1 4040093 c.610_612delCTCinsTG frameshift_variant&synonymous_variant 0.95 pyrazinamide
clpC1 4040105 c.600C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040168 c.537G>C synonymous_variant 0.94 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.94 pyrazinamide
clpC1 4040243 c.462C>A synonymous_variant 0.94 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040276 c.427_429delTCCinsAGT synonymous_variant 1.0 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040284 c.421C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040288 c.417C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040335 c.370C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040459 c.246C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040486 c.219G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040546 c.159G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040567 c.138C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.97 pyrazinamide
clpC1 4040576 c.129C>T synonymous_variant 0.97 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4040588 c.117T>C synonymous_variant 0.96 pyrazinamide
clpC1 4040594 c.111G>C synonymous_variant 0.95 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.88 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.82 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040687 c.18C>T synonymous_variant 0.82 pyrazinamide
clpC1 4040705 c.-1G>A upstream_gene_variant 0.79 pyrazinamide
clpC1 4040708 c.-4A>G upstream_gene_variant 0.77 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044201 c.81C>G synonymous_variant 1.0 pyrazinamide
panD 4044228 c.54C>A synonymous_variant 1.0 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 1.0 pyrazinamide
panD 4044240 c.42G>C synonymous_variant 1.0 pyrazinamide
panD 4044246 c.36C>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044249 c.33C>T synonymous_variant 1.0 pyrazinamide
panD 4044264 c.18G>C synonymous_variant 1.0 pyrazinamide
panD 4044273 c.9G>A synonymous_variant 1.0 pyrazinamide
glpK 4138558 p.Ala400Ser missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138564 c.1192C>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138577 c.1179G>A synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138580 c.1176C>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138619 c.1137C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139143 c.613T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139189 c.567G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139192 c.564G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139195 c.561G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139375 c.381T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139381 c.375G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139384 c.372G>T synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139408 c.348T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139417 c.339A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139420 c.336T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139435 c.321C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139438 c.318G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139441 c.315A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139447 c.309C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139453 c.303T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139459 c.297A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4239287 c.-576C>G upstream_gene_variant 1.0 ethambutol
embC 4239288 c.-575A>G upstream_gene_variant 1.0 ethambutol
embC 4239294 c.-569T>C upstream_gene_variant 1.0 ethambutol
embC 4239302 c.-561C>G upstream_gene_variant 1.0 ethambutol
embC 4239308 c.-555C>A upstream_gene_variant 1.0 ethambutol
embC 4239326 c.-537C>T upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239336 c.-527T>C upstream_gene_variant 1.0 ethambutol
embC 4239341 c.-522G>A upstream_gene_variant 1.0 ethambutol
embC 4239378 c.-485T>C upstream_gene_variant 1.0 ethambutol
embC 4239383 c.-480C>T upstream_gene_variant 1.0 ethambutol
embC 4239389 c.-474C>T upstream_gene_variant 1.0 ethambutol
embC 4239392 c.-471C>T upstream_gene_variant 1.0 ethambutol
embC 4239398 c.-465G>C upstream_gene_variant 1.0 ethambutol
embC 4239401 c.-462A>T upstream_gene_variant 1.0 ethambutol
embC 4239408 c.-455G>A upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4240726 c.864G>C synonymous_variant 0.83 ethambutol Not assoc w R - Interim
embC 4240736 p.Ser292Ala missense_variant 0.85 ethambutol
embC 4240774 c.912C>A synonymous_variant 0.95 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.96 ethambutol
embC 4240786 c.924C>A synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 1.0 ethambutol
embC 4240822 c.960C>G synonymous_variant 1.0 ethambutol
embC 4240831 c.969T>C synonymous_variant 1.0 ethambutol
embC 4240873 c.1011C>G synonymous_variant 1.0 ethambutol
embC 4240875 p.Ser338Thr missense_variant 1.0 ethambutol
embC 4240879 c.1017G>C synonymous_variant 1.0 ethambutol
embC 4240880 p.Ala340Thr missense_variant 1.0 ethambutol Uncertain significance
embC 4240885 c.1023T>C synonymous_variant 1.0 ethambutol
embC 4240897 c.1035C>G synonymous_variant 1.0 ethambutol Not assoc w R
embC 4240900 c.1038A>G synonymous_variant 1.0 ethambutol
embC 4240936 c.1074A>C synonymous_variant 1.0 ethambutol
embC 4240990 c.1128A>G synonymous_variant 1.0 ethambutol
embC 4240996 c.1134G>A synonymous_variant 1.0 ethambutol
embC 4241017 c.1155T>C synonymous_variant 1.0 ethambutol
embC 4241023 c.1161T>G synonymous_variant 1.0 ethambutol
embC 4241024 p.Val388Phe missense_variant 1.0 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241047 c.1185C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241074 c.1212G>C synonymous_variant 1.0 ethambutol
embC 4241077 c.1215C>G synonymous_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241101 c.1239G>C synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241110 c.1248G>C synonymous_variant 1.0 ethambutol
embC 4241134 c.1272G>A synonymous_variant 1.0 ethambutol
embC 4241140 c.1278A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241158 c.1296T>C synonymous_variant 1.0 ethambutol
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241167 c.1305C>G synonymous_variant 1.0 ethambutol
embC 4241182 c.1320G>C synonymous_variant 1.0 ethambutol
embC 4241203 c.1341T>C synonymous_variant 1.0 ethambutol
embA 4244070 p.Val280Ile missense_variant 1.0 ethambutol
embA 4244075 c.843C>G synonymous_variant 1.0 ethambutol
embA 4244084 c.852C>G synonymous_variant 1.0 ethambutol
embA 4244085 p.Pro285Gly missense_variant 1.0 ethambutol
embA 4244100 c.868_870delGTAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245041 c.1809C>G synonymous_variant 1.0 ethambutol
embA 4245042 p.Thr604Ala missense_variant 1.0 ethambutol
embA 4245053 c.1821G>C synonymous_variant 1.0 ethambutol
embA 4245060 c.1828T>C synonymous_variant 1.0 ethambutol
embA 4245077 c.1845G>C synonymous_variant 1.0 ethambutol
embA 4245083 c.1851A>C synonymous_variant 1.0 ethambutol
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245125 c.1893G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245136 p.Tyr635Phe missense_variant 1.0 ethambutol
embA 4245149 c.1917C>G synonymous_variant 1.0 ethambutol
embA 4245152 c.1920C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245182 c.1950T>C synonymous_variant 1.0 ethambutol
embA 4245185 c.1953G>T synonymous_variant 1.0 ethambutol
embA 4245186 p.Thr652Ala missense_variant 1.0 ethambutol
embA 4245200 c.1968C>G synonymous_variant 1.0 ethambutol
embA 4245206 c.1974A>G synonymous_variant 1.0 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245224 c.1992T>C synonymous_variant 1.0 ethambutol
embA 4245248 c.2016G>C synonymous_variant 1.0 ethambutol
embA 4245257 c.2025A>G synonymous_variant 1.0 ethambutol
embA 4245263 c.2031A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245275 c.2043C>T synonymous_variant 1.0 ethambutol
embA 4245285 c.2053T>C synonymous_variant 1.0 ethambutol
embA 4245290 c.2058C>G synonymous_variant 1.0 ethambutol
embB 4245683 c.-831C>G upstream_gene_variant 0.9 ethambutol
embA 4245693 p.Ile821Val missense_variant 0.95 ethambutol
embA 4245707 c.2475C>T synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4245725 c.-789A>G upstream_gene_variant 0.89 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 0.89 ethambutol
embB 4245734 c.-780G>C upstream_gene_variant 0.89 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 0.89 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 0.89 ethambutol
embB 4245743 c.-771C>A upstream_gene_variant 0.9 ethambutol
embB 4245764 c.-750G>C upstream_gene_variant 0.96 ethambutol
embA 4245772 p.Asn847Thr missense_variant 0.96 ethambutol
embB 4245791 c.-723C>G upstream_gene_variant 0.96 ethambutol
embB 4245797 c.-717C>G upstream_gene_variant 0.95 ethambutol
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4245812 c.-702G>C upstream_gene_variant 1.0 ethambutol
embB 4245815 c.-699C>G upstream_gene_variant 1.0 ethambutol
embA 4245821 p.Ser863Arg missense_variant 1.0 ethambutol
embA 4245822 p.Pro864Ala missense_variant 1.0 ethambutol
embB 4245830 c.-684G>C upstream_gene_variant 1.0 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 1.0 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 1.0 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 1.0 ethambutol
embA 4246021 p.Ala930Gly missense_variant 1.0 ethambutol
embB 4246028 c.-486G>T upstream_gene_variant 1.0 ethambutol
embA 4246037 c.2805G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4246041 p.Asp937Asn missense_variant 1.0 ethambutol
embA 4246045 p.Val938Ala missense_variant 1.0 ethambutol
embB 4246049 c.-465G>A upstream_gene_variant 1.0 ethambutol
embA 4246055 c.2823T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4246080 c.2848_2850delCCTinsTC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embB 4246097 c.-417C>G upstream_gene_variant 1.0 ethambutol
embB 4246109 c.-405C>G upstream_gene_variant 1.0 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 1.0 ethambutol
embB 4246208 c.-306G>A upstream_gene_variant 1.0 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 1.0 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 1.0 ethambutol
embA 4246220 c.2988T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 1.0 ethambutol
embB 4246229 c.-285T>C upstream_gene_variant 1.0 ethambutol
embA 4246232 c.3000C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4246235 c.3003G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246254 c.-260C>T upstream_gene_variant 1.0 ethambutol
embB 4246259 c.-255G>C upstream_gene_variant 1.0 ethambutol
embB 4247380 c.867C>G synonymous_variant 1.0 ethambutol
embB 4247389 c.876C>G synonymous_variant 1.0 ethambutol
embB 4247395 c.882C>G synonymous_variant 1.0 ethambutol
embB 4247398 c.885G>C synonymous_variant 1.0 ethambutol
embB 4247401 c.888T>C synonymous_variant 1.0 ethambutol
embB 4247404 c.891G>C synonymous_variant 1.0 ethambutol
embB 4247407 c.894G>C synonymous_variant 1.0 ethambutol
embB 4247413 c.900C>T synonymous_variant 1.0 ethambutol
embB 4247423 c.910C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247437 c.924A>C synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.98 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.97 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.97 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.97 ethambutol
embB 4247527 c.1014G>A synonymous_variant 0.95 ethambutol
embB 4247779 c.1266C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
embB 4247785 c.1272G>C synonymous_variant 0.92 ethambutol
embB 4248035 p.Val508Ile missense_variant 1.0 ethambutol
embB 4248042 p.Ala510Gly missense_variant 1.0 ethambutol
embB 4248044 p.Lys511Ala missense_variant 1.0 ethambutol
embB 4248052 c.1539G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248055 c.1542G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248064 c.1551G>T synonymous_variant 1.0 ethambutol
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 1.0 ethambutol
embB 4248094 c.1581C>T synonymous_variant 1.0 ethambutol
embB 4248095 c.1582_1584delCTCinsTG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248115 c.1602C>T synonymous_variant 1.0 ethambutol Not assoc w R
embB 4248124 c.1611G>A synonymous_variant 1.0 ethambutol
embB 4248127 c.1614G>C synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248133 c.1620C>G synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4248161 c.1648C>T synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4248169 c.1656C>T synonymous_variant 0.97 ethambutol Not assoc w R - Interim
embB 4248181 c.1668C>T synonymous_variant 0.98 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.98 ethambutol Uncertain significance
embB 4248220 c.1707A>G synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embB 4248256 c.1743C>G synonymous_variant 0.96 ethambutol
embB 4248266 c.1753C>T synonymous_variant 0.93 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.92 ethambutol
embB 4248301 c.1788C>T synonymous_variant 0.89 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.88 ethambutol
embB 4248316 c.1803C>A synonymous_variant 0.87 ethambutol
embB 4248319 c.1806A>G synonymous_variant 0.87 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.86 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.89 ethambutol
embB 4248349 c.1836G>A synonymous_variant 0.91 ethambutol
embB 4248350 c.1837T>C synonymous_variant 0.9 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.9 ethambutol
embB 4248358 c.1845C>G synonymous_variant 0.9 ethambutol
embB 4248361 c.1848A>G synonymous_variant 0.95 ethambutol Not assoc w R - Interim
embB 4248362 p.Ser617Thr missense_variant 0.95 ethambutol
embB 4248368 c.1855C>T synonymous_variant 0.96 ethambutol
embB 4248409 c.1896A>G synonymous_variant 1.0 ethambutol
embB 4248410 c.1897_1899delTTCinsAG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248425 c.1912T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 1.0 ethambutol
embB 4248432 p.Trp640Phe missense_variant 1.0 ethambutol
embB 4248434 p.Ala641Ser missense_variant 1.0 ethambutol
embB 4248437 c.1924_1926delACCinsTG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248460 c.1947C>G synonymous_variant 1.0 ethambutol
embB 4248472 c.1959T>C synonymous_variant 1.0 ethambutol
embB 4249132 c.2619G>A synonymous_variant 1.0 ethambutol
embB 4249138 c.2625C>G synonymous_variant 1.0 ethambutol
embB 4249141 c.2628G>C synonymous_variant 1.0 ethambutol
embB 4249144 c.2631G>C synonymous_variant 1.0 ethambutol
embB 4249147 c.2634C>G synonymous_variant 1.0 ethambutol
embB 4249150 c.2637C>G synonymous_variant 1.0 ethambutol
embB 4249156 c.2643C>A synonymous_variant 1.0 ethambutol
embB 4249165 c.2652C>G synonymous_variant 1.0 ethambutol
embB 4249186 c.2673G>A synonymous_variant 1.0 ethambutol
embB 4249187 p.Tyr892His missense_variant 1.0 ethambutol
embB 4249381 c.2868A>C synonymous_variant 1.0 ethambutol
embB 4249390 c.2877C>T synonymous_variant 1.0 ethambutol
embB 4249417 c.2904A>G synonymous_variant 1.0 ethambutol
embB 4249429 c.2916C>T synonymous_variant 1.0 ethambutol
embB 4249432 c.2919A>G synonymous_variant 1.0 ethambutol
embB 4249441 c.2928A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249444 c.2931T>C synonymous_variant 1.0 ethambutol
embB 4249447 c.2934G>C synonymous_variant 1.0 ethambutol
embB 4249454 p.Thr981Ser missense_variant 1.0 ethambutol
embB 4249469 p.Leu986Met missense_variant 1.0 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249525 c.3012T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4249528 c.3015C>A synonymous_variant 1.0 ethambutol
embB 4249529 p.Ile1006Val missense_variant 1.0 ethambutol
embB 4249532 p.Ala1007Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4249537 c.3024A>G synonymous_variant 1.0 ethambutol
embB 4249540 c.3027C>T synonymous_variant 1.0 ethambutol
embB 4249558 c.3045A>G synonymous_variant 1.0 ethambutol
embB 4249568 c.3055_3057delTCGinsAC frameshift_variant&missense_variant 1.0 ethambutol
embB 4249573 c.3060T>C synonymous_variant 1.0 ethambutol
embB 4249581 p.Leu1023Gln missense_variant 1.0 ethambutol
aftB 4267583 c.1254C>G synonymous_variant 0.9 ethambutol
aftB 4267586 c.1251C>G synonymous_variant 0.91 ethambutol
aftB 4267613 c.1224C>G synonymous_variant 0.93 ethambutol
aftB 4267622 c.1215G>C synonymous_variant 0.93 ethambutol
aftB 4267625 c.1212T>C synonymous_variant 0.93 ethambutol
aftB 4267636 c.1201C>A synonymous_variant 0.92 ethambutol
aftB 4267838 c.999T>C synonymous_variant 1.0 ethambutol
aftB 4267844 c.993C>A synonymous_variant 1.0 ethambutol
aftB 4267867 c.970C>T synonymous_variant 1.0 ethambutol
aftB 4267868 c.969G>C synonymous_variant 1.0 ethambutol
aftB 4267879 p.Val320Leu missense_variant 1.0 ethambutol
aftB 4267898 c.939T>C synonymous_variant 0.9 ethambutol
aftB 4267911 p.Pro309Leu missense_variant 0.9 ethambutol
aftB 4268350 p.Arg163Trp missense_variant 0.91 ethambutol
aftB 4268356 p.Pro161Ala missense_variant 0.92 ethambutol
aftB 4268360 c.477A>G synonymous_variant 0.93 ethambutol Not assoc w R - Interim
aftB 4268386 c.451T>C synonymous_variant 0.94 ethambutol
aftB 4268393 c.444G>C synonymous_variant 0.94 ethambutol Not assoc w R - Interim
aftB 4268396 c.441T>C synonymous_variant 0.94 ethambutol
aftB 4268404 p.Leu145Met missense_variant 0.94 ethambutol
aftB 4268411 c.426G>A synonymous_variant 0.94 ethambutol
aftB 4268417 c.420G>A synonymous_variant 1.0 ethambutol
aftB 4268423 c.414C>T synonymous_variant 1.0 ethambutol
aftB 4268432 c.405C>G synonymous_variant 1.0 ethambutol
ubiA 4269180 c.654G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269186 c.-350C>A upstream_gene_variant 1.0 ethambutol
aftB 4269213 c.-377C>T upstream_gene_variant 1.0 ethambutol
ubiA 4269220 p.Ala205Lys missense_variant 1.0 ethambutol
ubiA 4269222 c.612T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269572 c.-736A>C upstream_gene_variant 1.0 ethambutol
aftB 4269573 c.-737A>G upstream_gene_variant 1.0 ethambutol
ubiA 4269585 c.249G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4269594 c.-758A>C upstream_gene_variant 1.0 ethambutol
ubiA 4269606 c.228T>C synonymous_variant 1.0 ethambutol Not assoc w R
aftB 4269609 c.-773G>C upstream_gene_variant 1.0 ethambutol
aftB 4269612 c.-776T>C upstream_gene_variant 1.0 ethambutol
ethA 4328443 c.-970C>G upstream_gene_variant 0.92 ethionamide
ethA 4328470 c.-998_-997delAGinsGC upstream_gene_variant 1.0 ethionamide
ethA 4328473 c.-1000G>C upstream_gene_variant 1.0 ethionamide