TB-Profiler result

Run: ERR502524
Summary

Run ID: ERR502524

Sample name:

Date: 2024-10-04T05:29:58.943533

Number of reads: 740441

Percentage reads mapped: 16.74

Median coverage: 10.0

Strain: lineage4.9;lineage6.3

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.3 West-Africa 2 RD702 0.07
lineage3.1.2.2 East-African-Indian RD750 0.13
lineage4 Euro-American None 0.77
lineage4.9 Euro-American (H37Rv-like) None 0.89
La1.7.1 M.bovis None 0.18
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ile335Thr Mutation from literature
p.Ile317Leu Mutation from literature
ethambutol embB p.His312Arg Mutation from literature
p.Ala356Val Uncertain significance Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance Mutation from literature
katG 2155107 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
katG 2155161 p.Ile317Leu missense_variant 0.91 isoniazid Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.39 ethambutol Mutation from literature
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 0.85 isoniazid
dnaA 24 c.24C>T synonymous_variant 0.85 isoniazid
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 33 c.33A>C synonymous_variant 1.0 isoniazid
dnaA 60 c.60T>C synonymous_variant 1.0 isoniazid
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 714 c.714C>G synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 717 c.717C>T synonymous_variant 0.81 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>A synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 771 c.771A>G synonymous_variant 1.0 isoniazid
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.83 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCTT synonymous_variant 0.97 isoniazid
dnaA 819 c.819C>T synonymous_variant 0.97 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.97 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.97 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.97 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.97 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.97 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.97 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.78 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.96 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.95 isoniazid
dnaA 891 c.891C>T synonymous_variant 0.64 isoniazid Not assoc w R - Interim
dnaA 897 c.897A>G synonymous_variant 0.94 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.55 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>G synonymous_variant 0.86 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.92 isoniazid
dnaA 915 c.915C>T synonymous_variant 0.52 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.96 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 936 c.936C>G synonymous_variant 0.39 isoniazid
dnaA 939 c.939C>G synonymous_variant 0.41 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.96 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.95 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.94 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.93 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.93 isoniazid
dnaA 969 c.969G>A synonymous_variant 1.0 isoniazid
dnaA 984 c.984T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 1.0 isoniazid
dnaA 996 c.996A>G synonymous_variant 1.0 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.73 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.73 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 1.0 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 0.78 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.84 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 1.0 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.69 isoniazid
dnaA 1078 c.1078_1080delCTCinsTTG synonymous_variant 0.67 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1095 c.1095C>T synonymous_variant 0.57 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.43 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 1.0 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 1.0 isoniazid
dnaA 1173 c.1173C>T synonymous_variant 0.95 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.95 isoniazid
dnaA 1180 c.1180C>T synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 1.0 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 0.9 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.9 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.9 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 0.76 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.74 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 0.64 isoniazid
dnaA 1311 c.1311C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1314 c.1314A>G synonymous_variant 0.36 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1320 c.1320G>C synonymous_variant 0.44 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 1.0 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 1.0 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.69 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 1.0 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.63 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.59 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.6 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.97 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.97 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.97 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 0.56 isoniazid
dnaA 1437 c.1437G>A synonymous_variant 0.56 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.56 isoniazid
dnaA 1446 c.1446C>G synonymous_variant 0.59 isoniazid Not assoc w R - Interim
dnaA 1449 c.1449G>A synonymous_variant 0.38 isoniazid
dnaA 1461 c.1461C>A synonymous_variant 0.96 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 0.72 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 0.74 isoniazid Not assoc w R - Interim
dnaA 1497 c.1497T>G synonymous_variant 0.94 isoniazid
dnaA 1500 c.1500C>G synonymous_variant 0.83 isoniazid
dnaA 1506 c.1506T>A synonymous_variant 1.0 isoniazid
gyrB 5326 c.87T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5329 c.90C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5338 c.99C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5344 c.105C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5359 c.120C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 5362 c.123T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5363 c.124_126delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5396 p.Ala53Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6316 c.-986G>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.66 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.62 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6362 c.-940_-938delTTGinsCTC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6376 c.-926G>A upstream_gene_variant 0.36 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.37 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6397 c.1158G>A synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6403 c.-899T>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.4 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6674 c.-628_-626delCTTinsTTG upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6902 c.-400_-398delCTCinsTTG upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.75 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6997 c.-305G>A upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>T upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>G upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7076 c.-226_-224delCTAinsTTG upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>G upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7174 c.-128C>T upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7643 c.342C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7646 c.345C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7673 c.372G>A synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7742 c.441G>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTTG synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7820 c.519G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7884 p.Arg195Gly missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7892 c.591G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7901 c.600G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7904 c.603G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8121 c.820_822delTTGinsCTC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8126 c.825G>C synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8129 c.828T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8135 c.834C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8237 c.936A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8247 p.Ile316Val missense_variant 0.43 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.73 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8693 c.1392T>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8708 c.1407G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8765 p.Asp488Glu missense_variant 0.87 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8789 c.1488C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8798 c.1497C>T synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.67 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8818 p.Ser506Asn missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 0.36 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8840 c.1539C>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8888 c.1587C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>G synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8933 c.1632G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8936 c.1635G>A synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8983 p.Cys561Ser missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>A synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 0.5 levofloxacin
moxifloxacin
gyrA 9191 c.1890G>C synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.36 levofloxacin
moxifloxacin
gyrA 9224 c.1923C>T synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 9239 c.1938C>T synonymous_variant 0.36 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9242 c.1941A>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9326 c.2025G>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9435 c.2134C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9638 c.2337C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9674 c.2373T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9704 c.2403T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9708 c.2407T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
Rv0010c 13884 c.-326A>G upstream_gene_variant 0.8 isoniazid
Rv0010c 13890 c.-332T>C upstream_gene_variant 1.0 isoniazid
Rv0010c 13893 c.-335T>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13894 c.-336C>T upstream_gene_variant 0.75 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 1.0 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 1.0 isoniazid
fgd1 490827 c.45C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490848 c.66A>G synonymous_variant 0.62 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490854 c.72C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490868 p.Ala29Gly missense_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 490890 c.108C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490917 c.135C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490921 p.Gln47Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490929 c.147C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490932 c.150T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490948 p.Ser56Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490971 c.189A>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490980 p.Asn66Lys missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490983 c.201G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490988 p.Leu69Gln missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490995 c.213C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491016 c.234C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491040 c.258C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491136 c.354C>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491151 c.369G>A synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491168 p.Phe129Tyr missense_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491178 c.396G>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fgd1 491223 c.441C>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491265 c.483G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491290 p.Val170Ile missense_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491296 p.Val172Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491307 c.525C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491310 c.528C>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491320 p.Ala180Gln missense_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491325 c.543G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491607 c.825G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491613 c.831C>T synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491640 c.858G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491646 c.864G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fgd1 491658 c.876A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491661 c.879C>G synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fgd1 491673 c.891A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491676 c.894T>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491679 c.897A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491686 p.Thr302Gln missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491697 c.915G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491704 c.922C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491709 c.927A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491712 c.930T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 574607 c.-741G>A upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574610 c.-738G>A upstream_gene_variant 0.93 isoniazid
ethionamide
mshA 574616 c.-732G>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574640 c.-708G>A upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574646 c.-702G>A upstream_gene_variant 0.95 isoniazid
ethionamide
mshA 574650 c.-698A>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574667 c.-681G>A upstream_gene_variant 0.94 isoniazid
ethionamide
mshA 574673 c.-675A>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574676 c.-672G>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 574683 c.-665T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 574688 c.-660G>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575000 c.-348C>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575009 c.-339T>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575011 c.-337G>A upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575022 c.-326C>T upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575034 c.-314_-312delTTAinsCTG upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575042 c.-306T>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575045 c.-303C>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575051 c.-297A>G upstream_gene_variant 0.95 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575072 c.-276G>C upstream_gene_variant 0.88 isoniazid
ethionamide
mshA 575075 c.-273T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 575081 c.-267A>G upstream_gene_variant 0.88 isoniazid
ethionamide
mshA 575087 c.-261C>G upstream_gene_variant 0.83 isoniazid
ethionamide
mshA 575109 c.-239G>T upstream_gene_variant 0.75 isoniazid
ethionamide
mshA 575114 c.-234G>A upstream_gene_variant 0.73 isoniazid Uncertain significance
ethionamide
mshA 575117 c.-231T>C upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575118 c.-230A>G upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 575123 c.-225A>G upstream_gene_variant 0.7 isoniazid
ethionamide
mshA 575124 c.-224_-222delGGGinsCGT upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575144 c.-204T>G upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575153 c.-195C>A upstream_gene_variant 0.7 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 575161 c.-187_-186delTTinsCC upstream_gene_variant 1.0 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575542 c.195C>G synonymous_variant 0.47 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 1.0 isoniazid
ethionamide
mshA 575569 c.222A>G synonymous_variant 0.53 isoniazid
ethionamide
mshA 575571 p.Ser75Thr missense_variant 0.53 isoniazid
ethionamide
mshA 575576 c.229C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575581 c.234C>T synonymous_variant 0.53 isoniazid
ethionamide
mshA 575587 c.240C>G synonymous_variant 0.53 isoniazid
ethionamide
mshA 575674 c.327G>C synonymous_variant 0.5 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575701 c.354G>A synonymous_variant 0.4 isoniazid
ethionamide
mshA 575704 c.357T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575767 c.420G>A synonymous_variant 0.7 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575779 p.Glu144Asp missense_variant 1.0 isoniazid
ethionamide
mshA 575780 p.Pro145Ala missense_variant 0.69 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 0.61 isoniazid
ethionamide
mshA 575845 c.498C>G synonymous_variant 0.59 isoniazid
ethionamide
mshA 575848 c.501C>T synonymous_variant 0.59 isoniazid
ethionamide
mshA 575851 c.504C>G synonymous_variant 0.59 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575887 c.540G>T synonymous_variant 0.67 isoniazid
ethionamide
mshA 575890 c.543C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575899 c.552G>A synonymous_variant 0.7 isoniazid
ethionamide
mshA 575916 p.Asp190Val missense_variant 0.74 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619584 c.-307A>T upstream_gene_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 619588 c.-303C>G upstream_gene_variant 0.38 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619609 c.-282G>T upstream_gene_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 619624 c.-267C>T upstream_gene_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257_-255delTCCinsGTG upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619645 c.-246G>C upstream_gene_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>G upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619669 c.-222G>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>C upstream_gene_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619684 c.-207G>A upstream_gene_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 619912 p.Val8Ile missense_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619923 c.33C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 619935 c.45C>T synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619953 c.63C>G synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 619984 c.94C>T synonymous_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620197 p.Gln103Met missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620238 c.348G>C synonymous_variant 0.79 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620253 c.363G>C synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620271 c.381C>G synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.47 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620291 p.Tyr134Phe missense_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>T synonymous_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620310 c.420C>T synonymous_variant 0.47 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 620343 c.453G>C synonymous_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>T synonymous_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620376 c.486G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620389 c.499C>T synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620424 c.534G>C synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620433 c.543C>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620436 c.546T>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620589 c.699G>T synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620607 c.717T>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620613 c.723C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620652 c.762C>G synonymous_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620685 c.795G>A synonymous_variant 0.89 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin
ccsA 620698 p.Val270Ile missense_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620712 c.822G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620781 c.891C>G synonymous_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620783 p.Ala298Val missense_variant 0.97 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620796 c.906C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620829 c.939G>C synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620835 c.945C>G synonymous_variant 0.93 kanamycin
capreomycin
amikacin
Rv0565c 656052 c.1419A>C synonymous_variant 1.0 ethionamide
Rv0565c 656073 c.1396_1398delTTGinsCTC synonymous_variant 1.0 ethionamide
Rv0565c 656076 c.1395C>T synonymous_variant 0.79 ethionamide
Rv0565c 656085 c.1386A>G synonymous_variant 1.0 ethionamide
Rv0565c 656088 c.1383A>G synonymous_variant 1.0 ethionamide
Rv0565c 656091 c.1380T>C synonymous_variant 0.79 ethionamide
Rv0565c 656112 c.1359C>G synonymous_variant 0.92 ethionamide
Rv0565c 656265 c.1206G>C synonymous_variant 0.94 ethionamide
Rv0565c 656268 p.Met401Ile missense_variant 0.93 ethionamide
Rv0565c 656277 c.1194C>G synonymous_variant 0.47 ethionamide
Rv0565c 656292 c.1179G>C synonymous_variant 0.54 ethionamide
Rv0565c 656304 c.1167T>C synonymous_variant 0.92 ethionamide
Rv0565c 656307 c.1164G>C synonymous_variant 0.58 ethionamide
Rv0565c 656310 c.1161T>C synonymous_variant 0.64 ethionamide
Rv0565c 656322 c.1149C>T synonymous_variant 0.64 ethionamide
Rv0565c 656325 c.1146C>G synonymous_variant 1.0 ethionamide
Rv0565c 656334 c.1137A>G synonymous_variant 0.7 ethionamide
Rv0565c 656448 p.Ile341Val missense_variant 1.0 ethionamide
Rv0565c 656454 c.1017G>C synonymous_variant 1.0 ethionamide
Rv0565c 656457 c.1014T>C synonymous_variant 1.0 ethionamide
Rv0565c 656469 c.1002T>C synonymous_variant 1.0 ethionamide
Rv0565c 656475 c.996A>G synonymous_variant 1.0 ethionamide
Rv0565c 656484 c.987T>C synonymous_variant 1.0 ethionamide
Rv0565c 656487 c.984T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 656493 c.978C>G synonymous_variant 0.9 ethionamide
Rv0565c 657183 c.288G>A synonymous_variant 0.91 ethionamide
Rv0565c 657189 c.282C>A synonymous_variant 1.0 ethionamide
Rv0565c 657193 p.Met93Thr missense_variant 1.0 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 1.0 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657210 c.261C>T synonymous_variant 0.82 ethionamide Not assoc w R - Interim
Rv0565c 657213 c.258C>T synonymous_variant 0.78 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 1.0 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 1.0 ethionamide
Rv0565c 657240 p.Glu77Lys missense_variant 0.82 ethionamide
Rv0565c 657252 c.219G>C synonymous_variant 0.82 ethionamide
Rv0565c 657255 c.216G>A synonymous_variant 0.81 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657294 c.177C>A synonymous_variant 0.62 ethionamide
Rv0565c 657300 c.171C>G synonymous_variant 0.37 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.59 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 0.57 ethionamide
Rv0565c 657312 c.159C>T synonymous_variant 0.58 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.96 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.95 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.47 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.92 ethionamide Uncertain significance
Rv0565c 657342 c.129T>C synonymous_variant 0.91 ethionamide
Rv0565c 657356 p.Ile39Val missense_variant 0.8 ethionamide
Rv0565c 657359 p.Thr38Ala missense_variant 0.9 ethionamide
Rv0565c 657626 c.-156C>G upstream_gene_variant 0.6 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.64 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.62 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 0.68 ethionamide
Rv0565c 657668 c.-198C>T upstream_gene_variant 0.7 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657695 c.-225C>G upstream_gene_variant 0.79 ethionamide
Rv0565c 657725 c.-255G>A upstream_gene_variant 0.68 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 0.71 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731687 c.-243_-237delGCAAGACinsATGTGCAT upstream_gene_variant 0.94 isoniazid
hadA 731695 c.-235C>T upstream_gene_variant 0.89 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 0.95 isoniazid
hadA 731708 c.-222G>A upstream_gene_variant 0.96 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.96 isoniazid
hadA 731726 c.-204C>G upstream_gene_variant 0.74 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.73 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.65 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 0.65 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.7 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.75 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.79 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732280 c.351C>G synonymous_variant 0.47 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.45 isoniazid
hadA 732305 p.Ile126Val missense_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.5 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.48 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Ile missense_variant 1.0 isoniazid
hadA 732337 c.408G>A synonymous_variant 0.41 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.62 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734093 c.-161A>C upstream_gene_variant 1.0 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.67 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 1.0 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 1.0 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734123 c.-131C>G upstream_gene_variant 0.55 rifampicin
nusG 734129 c.-125G>C upstream_gene_variant 1.0 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.55 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.57 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 1.0 rifampicin
nusG 734183 c.-71C>T upstream_gene_variant 1.0 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
nusG 734203 c.-51_-50delTGinsCC upstream_gene_variant 0.88 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 1.0 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.88 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 1.0 rifampicin
nusG 734225 c.-29C>T upstream_gene_variant 1.0 rifampicin
nusG 734229 c.-25A>T upstream_gene_variant 1.0 rifampicin
nusG 734230 c.-24G>A upstream_gene_variant 1.0 rifampicin
nusG 734233 c.-21T>C upstream_gene_variant 1.0 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 1.0 rifampicin
nusG 734373 c.120G>C synonymous_variant 0.91 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.73 rifampicin
nusG 734407 p.Val52Ile missense_variant 1.0 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.72 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.74 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.82 rifampicin
nusG 734520 c.267C>A synonymous_variant 0.77 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
nusG 734556 c.303C>T synonymous_variant 0.35 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.6 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734596 c.343T>C synonymous_variant 1.0 rifampicin
nusG 734601 c.348C>G synonymous_variant 0.63 rifampicin
nusG 734610 c.357C>G synonymous_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 1.0 rifampicin
nusG 734820 c.567A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>T synonymous_variant 1.0 rifampicin
nusG 734844 c.591G>A synonymous_variant 0.81 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734862 c.609C>G synonymous_variant 0.84 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.84 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.83 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734931 c.678A>T synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734943 c.690G>C synonymous_variant 0.81 rifampicin
nusG 734950 p.Gly233Thr missense_variant 1.0 rifampicin
mmaA3 738309 c.-160G>C upstream_gene_variant 0.9 isoniazid
mmaA3 738315 c.-166G>A upstream_gene_variant 0.47 isoniazid
mmaA3 738333 c.-184C>G upstream_gene_variant 0.47 isoniazid
mmaA3 738339 c.-190G>C upstream_gene_variant 0.61 isoniazid
mmaA3 738346 c.-198_-197delCTinsGC upstream_gene_variant 1.0 isoniazid
mmaA3 738348 c.-199G>C upstream_gene_variant 0.83 isoniazid
rpoB 760046 c.240G>C synonymous_variant 1.0 rifampicin
rpoB 760056 c.250_252delCTCinsTTG synonymous_variant 0.73 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.67 rifampicin
rpoB 760181 c.375T>A synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760271 c.465C>G synonymous_variant 0.78 rifampicin
rpoB 760274 c.468G>A synonymous_variant 0.78 rifampicin
rpoB 760295 c.489C>T synonymous_variant 0.81 rifampicin
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.84 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760358 c.552C>G synonymous_variant 0.74 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760412 c.606C>T synonymous_variant 1.0 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.65 rifampicin
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>G synonymous_variant 0.67 rifampicin
rpoB 760520 c.714C>G synonymous_variant 0.59 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760526 c.720G>A synonymous_variant 0.59 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760580 c.774G>A synonymous_variant 0.73 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760601 c.795C>T synonymous_variant 0.79 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760622 c.816C>T synonymous_variant 0.79 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.79 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.92 rifampicin
rpoB 760757 c.951T>C synonymous_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.98 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 1.0 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760916 c.1110C>G synonymous_variant 0.74 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.73 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760937 c.1131G>A synonymous_variant 0.71 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.64 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 1.0 rifampicin
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.66 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.65 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761129 c.1323G>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.74 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 1.0 rifampicin
rpoB 761192 c.1386C>G synonymous_variant 0.73 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 0.72 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.63 rifampicin
rpoB 761306 c.1500C>G synonymous_variant 0.35 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.32 rifampicin
rpoB 761345 c.1539G>T synonymous_variant 0.71 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761452 p.Val549Glu missense_variant 1.0 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 1.0 rifampicin
rpoB 761465 c.1659G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761471 c.1665C>T synonymous_variant 0.83 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.75 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.3 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>A synonymous_variant 1.0 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.76 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.74 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761728 c.1923dupC frameshift_variant 0.41 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.66 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 0.75 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761848 p.Cys681Ser missense_variant 0.97 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.65 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.35 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761913 p.Asp703Gln missense_variant 0.64 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.6 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.63 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>T synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 0.83 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.86 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.83 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762431 c.2625C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762509 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoC 762512 c.-858C>G upstream_gene_variant 0.91 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762563 c.-807G>A upstream_gene_variant 0.82 rifampicin
rpoC 762776 c.-594C>G upstream_gene_variant 0.67 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762795 p.Asp997Asn missense_variant 0.71 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762902 c.-468C>T upstream_gene_variant 0.81 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 0.8 rifampicin
rpoB 762926 c.3120C>T synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 0.81 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.68 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.85 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763241 c.-129G>A upstream_gene_variant 0.7 rifampicin
rpoC 763250 c.-120C>T upstream_gene_variant 0.72 rifampicin
rpoC 763253 c.-117G>T upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.67 rifampicin
rpoC 763265 c.-105G>A upstream_gene_variant 0.67 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTTG synonymous_variant 0.69 rifampicin
rpoC 763414 c.45T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.67 rifampicin
rpoC 763633 c.264T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.69 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.72 rifampicin
rpoC 763714 c.345G>T synonymous_variant 0.73 rifampicin
rpoC 763726 c.357C>T synonymous_variant 0.77 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763771 c.402C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 763780 c.411C>G synonymous_variant 0.72 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.74 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.75 rifampicin
rpoC 763804 c.435C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 0.82 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.82 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.84 rifampicin
rpoC 763963 c.594C>G synonymous_variant 1.0 rifampicin
rpoC 763967 p.Gly200Ser missense_variant 0.79 rifampicin
rpoC 763972 c.603C>T synonymous_variant 0.74 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.71 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.75 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764159 c.790C>T synonymous_variant 0.81 rifampicin
rpoC 764167 c.798G>A synonymous_variant 0.83 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764218 c.849C>T synonymous_variant 0.76 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>A synonymous_variant 0.75 rifampicin
rpoC 764246 c.877_879delCTCinsTTG synonymous_variant 0.75 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.69 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.6 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.61 rifampicin
rpoC 764338 c.969G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.44 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.31 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.79 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 1.0 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.71 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 1.0 rifampicin
rpoC 764605 c.1236G>A synonymous_variant 0.77 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 0.68 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.67 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 0.68 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.59 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 0.6 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1686delTCCinsAGT synonymous_variant 1.0 rifampicin
rpoC 765065 c.1696C>T synonymous_variant 0.53 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765223 c.1854G>C synonymous_variant 1.0 rifampicin
rpoC 765233 p.Ala622Ser missense_variant 1.0 rifampicin
rpoC 765247 c.1878C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765248 c.1879T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765251 c.1882_1884delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 0.96 rifampicin
rpoC 765283 c.1914C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.85 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 0.82 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 0.74 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 0.72 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765391 c.2022C>T synonymous_variant 0.65 rifampicin
rpoC 765404 p.Leu679Val missense_variant 0.37 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.59 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Ser missense_variant 0.67 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.63 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 0.62 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.8 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.84 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.83 rifampicin
rpoC 765625 c.2256C>T synonymous_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 0.79 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 0.76 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.99 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.98 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.98 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.98 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765904 c.2535C>T synonymous_variant 0.74 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.79 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.74 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766093 c.2724C>A synonymous_variant 0.72 rifampicin
rpoC 766095 p.Thr909Ser missense_variant 0.72 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.74 rifampicin
rpoC 766123 c.2754C>A synonymous_variant 0.81 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 1.0 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 1.0 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766147 c.2778C>T synonymous_variant 0.67 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.67 rifampicin Uncertain significance
rpoC 766270 c.2901G>C synonymous_variant 0.75 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 1.0 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 1.0 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 1.0 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 1.0 rifampicin
rpoC 766309 c.2940G>A synonymous_variant 0.78 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.78 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.77 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 0.71 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.99 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.69 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.69 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.72 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766504 c.3135G>C synonymous_variant 0.8 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.79 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 1.0 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 1.0 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 1.0 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 1.0 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 0.9 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.9 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.84 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 0.77 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.74 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 0.73 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.71 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766882 c.3513C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 766883 p.Ser1172Ala missense_variant 0.56 rifampicin Uncertain significance
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.59 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.38 rifampicin
rpoC 766996 c.3627C>G synonymous_variant 1.0 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767149 c.3780C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>A synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.35 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>G synonymous_variant 1.0 rifampicin
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
mmpL5 775909 p.Leu858Phe missense_variant 1.0 bedaquiline
clofazimine
mmpL5 775910 c.2571G>A synonymous_variant 0.88 bedaquiline
clofazimine
mmpL5 775916 c.2565T>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775921 c.2560C>T synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775937 c.2544G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775940 c.2541C>T synonymous_variant 0.86 bedaquiline
clofazimine
mmpL5 775943 c.2538C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775946 c.2535C>G synonymous_variant 0.69 bedaquiline
clofazimine
mmpL5 775951 c.2530C>T synonymous_variant 0.68 bedaquiline
clofazimine
mmpL5 775961 c.2520C>G synonymous_variant 0.9 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.84 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.97 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.97 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.96 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.7 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.97 bedaquiline
clofazimine
mmpL5 776030 c.2451G>T synonymous_variant 0.4 bedaquiline
clofazimine
mmpL5 776036 c.2445G>C synonymous_variant 0.88 bedaquiline
clofazimine
mmpL5 776039 c.2442C>G synonymous_variant 0.52 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 0.5 bedaquiline
clofazimine
mmpL5 776056 p.Val809Leu missense_variant 0.8 bedaquiline
clofazimine
mmpL5 777133 p.Val450Ile missense_variant 1.0 bedaquiline
clofazimine
mmpL5 777155 c.1326G>A synonymous_variant 0.8 bedaquiline
clofazimine
mmpL5 777158 c.1323C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777164 c.1317C>G synonymous_variant 0.8 bedaquiline
clofazimine
mmpL5 777170 c.1311T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777173 c.1308C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777176 p.Glu435Asp missense_variant 1.0 bedaquiline
clofazimine
mmpL5 777191 c.1290C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777194 c.1287A>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 777206 c.1275A>G synonymous_variant 0.64 bedaquiline
clofazimine
mmpL5 777212 p.Ala423Thr missense_variant 0.7 bedaquiline
clofazimine
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.74 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>T synonymous_variant 0.72 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.7 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.76 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.77 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.76 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.8 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.75 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>G synonymous_variant 1.0 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.79 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.81 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.8 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>G synonymous_variant 0.77 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781883 c.324G>A synonymous_variant 0.7 streptomycin
rpsL 781886 c.327C>T synonymous_variant 0.68 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.73 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.7 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 0.68 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.72 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.53 linezolid
rplC 800745 c.-64_-62delCTCinsTTG upstream_gene_variant 0.51 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.57 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.59 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.42 linezolid
rplC 800794 c.-15A>G upstream_gene_variant 0.34 linezolid
rplC 800796 c.-13A>G upstream_gene_variant 0.34 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800806 c.-3G>T upstream_gene_variant 0.54 linezolid
rplC 800807 c.-2_-1insT upstream_gene_variant 0.56 linezolid
rplC 800814 c.6A>G synonymous_variant 1.0 linezolid
rplC 800815 p.Arg3Ser missense_variant 0.6 linezolid
rplC 800820 c.12G>A synonymous_variant 0.6 linezolid
rplC 800829 c.21C>G synonymous_variant 0.59 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 0.71 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64_66delAGAinsCGG synonymous_variant 0.69 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800901 c.93C>G synonymous_variant 0.77 linezolid
rplC 800910 c.102C>T synonymous_variant 0.79 linezolid
rplC 800913 c.105G>A synonymous_variant 0.79 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800919 c.111C>G synonymous_variant 0.81 linezolid
rplC 800931 c.123G>C synonymous_variant 0.83 linezolid
rplC 800934 c.126C>G synonymous_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>A synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800962 p.Leu52Val missense_variant 0.81 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 801222 c.414T>C synonymous_variant 0.53 linezolid
rplC 801228 c.420T>C synonymous_variant 0.53 linezolid
rplC 801231 c.423C>T synonymous_variant 0.58 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>A synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801285 c.477G>A synonymous_variant 1.0 linezolid
rplC 801309 c.501C>G synonymous_variant 0.96 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801330 c.522G>T synonymous_variant 0.65 linezolid
rplC 801333 c.525G>C synonymous_variant 0.63 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801349 p.Leu181Val missense_variant 0.61 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.39 linezolid
rplC 801372 c.564G>A synonymous_variant 0.6 linezolid
rplC 801402 c.594T>C synonymous_variant 1.0 linezolid
rplC 801405 c.597T>C synonymous_variant 1.0 linezolid
rplC 801423 c.615G>C synonymous_variant 1.0 linezolid
rplC 801427 p.Met207Val missense_variant 1.0 linezolid
rplC 801442 p.Ile212Val missense_variant 0.47 linezolid
fbiC 1303441 c.511T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303449 c.519C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303462 p.Ala178Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303480 p.Gln184Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303488 c.558G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303506 c.576C>T synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303538 p.Arg203Leu missense_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303578 c.648G>A synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiC 1303596 c.666G>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303620 c.690C>T synonymous_variant 0.86 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303629 c.699C>T synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303659 c.729T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303661 p.Val244Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303674 c.744C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303704 c.774T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303729 c.799_801delCTAinsTTG synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303750 c.820_822delTTAinsCTG synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303755 c.825T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303779 c.849G>A synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1303782 c.852C>T synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303788 c.858T>C synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303800 c.870G>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1303812 c.882C>T synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303825 p.Glu299Gln missense_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303842 c.912C>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303866 p.Glu312Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303905 c.975G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303914 c.984C>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>T synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304001 c.1071C>T synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304019 c.1089C>T synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1304022 c.1092T>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304046 c.1116C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304055 c.1125C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304061 c.1131G>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1304063 p.Ala378Asp missense_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1304068 p.Val380Ile missense_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1304085 c.1155C>A synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1304087 p.Tyr386Phe missense_variant 0.75 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1304104 c.1174C>T synonymous_variant 0.67 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304161 p.Arg411Ser missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304169 c.1239T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304174 p.Val415Ala missense_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304178 c.1248G>A synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304184 c.1254G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304187 c.1257T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304190 c.1260G>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304196 c.1266C>A synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304205 c.1275C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304220 c.1290G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304222 p.Val431Ala missense_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304226 c.1296C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304227 p.Met433Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304496 c.1566T>A synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1304499 c.1569T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fbiC 1304502 c.1572G>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304532 c.1602G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304541 c.1611C>G synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304574 c.1644C>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304610 c.1680C>G synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304625 c.1695C>T synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304661 c.1731C>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304711 p.Ala594Glu missense_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304755 c.1825_1827delCTAinsTTG synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304760 c.1830G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1304778 c.1848T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>G synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1304797 p.Ala623Asn missense_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304823 c.1893C>T synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304826 c.1896G>A synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>G synonymous_variant 0.59 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304832 c.1902C>T synonymous_variant 0.41 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 0.61 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304868 c.1938G>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304869 p.Leu647Phe missense_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304872 c.1942_1943delAGinsTC synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1304875 p.Ile649Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304883 c.1953G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304891 p.Ile654Thr missense_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304915 p.Asp662Gly missense_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304934 c.2004C>G synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1304955 c.2025G>A synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304982 c.2052G>A synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304991 c.2061G>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305012 c.2082G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305030 c.2100G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305039 c.2109G>A synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305045 c.2115A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305331 p.Glu801Asn missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1305354 c.2424C>T synonymous_variant 0.52 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305357 c.2427C>G synonymous_variant 0.59 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305361 c.2431C>T synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1305393 c.2463T>C synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1305399 c.2469A>G synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fbiC 1305405 c.2475A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305414 c.2484G>A synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1305417 c.2487C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305423 c.2493T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305426 c.2496G>A synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1305427 c.2497C>T synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1305435 c.2505G>C synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1305444 c.2514A>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1305446 p.Gly839Ala missense_variant 0.85 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
sigE 1364634 c.222C>G synonymous_variant 1.0 pyrazinamide
sigE 1364640 c.228G>C synonymous_variant 1.0 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.95 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 0.95 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.95 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364745 c.333C>T synonymous_variant 0.95 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
sigE 1364751 c.339C>G synonymous_variant 1.0 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.97 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.93 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.89 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 1.0 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 1.0 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 0.93 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.93 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364892 c.480C>G synonymous_variant 0.96 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 1.0 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 1.0 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 1.0 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 1.0 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 1.0 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 1.0 pyrazinamide
sigE 1364964 c.552T>G synonymous_variant 1.0 pyrazinamide
sigE 1364967 c.555C>T synonymous_variant 1.0 pyrazinamide
sigE 1364973 c.561G>A synonymous_variant 1.0 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1364988 c.576G>A synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
sigE 1365003 c.591T>C synonymous_variant 0.95 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 1.0 pyrazinamide
sigE 1365019 c.607C>T synonymous_variant 0.85 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 1.0 pyrazinamide
embR 1416285 p.Glu355Gln missense_variant 1.0 ethambutol
embR 1416289 c.1059G>A synonymous_variant 1.0 ethambutol
embR 1416301 c.1047C>A synonymous_variant 1.0 ethambutol
embR 1416310 c.1038G>C synonymous_variant 1.0 ethambutol
embR 1416313 c.1035A>G synonymous_variant 1.0 ethambutol
embR 1416316 c.1032C>G synonymous_variant 1.0 ethambutol
embR 1416330 p.Val340Ile missense_variant 1.0 ethambutol
embR 1416332 p.Tyr339Phe missense_variant 1.0 ethambutol
embR 1416335 p.Asn338Ser missense_variant 1.0 ethambutol
embR 1416343 c.1005G>C synonymous_variant 1.0 ethambutol
embR 1416364 c.984C>T synonymous_variant 1.0 ethambutol
embR 1416386 p.Asp321Ala missense_variant 1.0 ethambutol
embR 1416388 c.960A>G synonymous_variant 1.0 ethambutol
embR 1416393 p.Val319Ile missense_variant 1.0 ethambutol Uncertain significance
atpE 1460807 c.-238C>T upstream_gene_variant 0.82 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460828 c.-217C>T upstream_gene_variant 0.77 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.98 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460895 c.-150_-148delGCAinsTCC upstream_gene_variant 0.75 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460904 c.-141C>T upstream_gene_variant 0.75 bedaquiline
atpE 1460918 c.-127A>G upstream_gene_variant 1.0 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>T synonymous_variant 1.0 bedaquiline
atpE 1461194 c.150C>T synonymous_variant 0.9 bedaquiline
atpE 1461197 c.153A>G synonymous_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.97 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.98 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.88 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.73 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.73 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.7 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.7 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.76 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.74 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.82 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1473918 n.261C>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.62 capreomycin
linezolid
rrl 1473943 n.286G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsAT non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473994 n.337C>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474011 n.354G>A non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474018 n.361G>A non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1474030 n.373G>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.81 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474110 n.453A>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474409 n.756_774delACCCACACGCGCATACGCG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474433 n.776G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474435 n.779_783delTGAAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.75 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475018 n.1361G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475404 n.1747A>G non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.76 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 0.85 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.7 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103_2106delCCGCinsTCGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.72 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.77 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.71 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673499 c.-703T>C upstream_gene_variant 0.73 isoniazid Uncertain significance
ethionamide
inhA 1673505 c.-697A>T upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673517 c.-685G>C upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673524 c.-678C>T upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673535 c.-667A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673565 c.-637G>C upstream_gene_variant 0.82 isoniazid
ethionamide
inhA 1673633 c.-569G>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673637 c.-565C>G upstream_gene_variant 0.64 isoniazid
ethionamide
inhA 1673641 c.-561G>A upstream_gene_variant 0.69 isoniazid
ethionamide
inhA 1673646 c.-556T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673657 c.-545C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673660 c.-542C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673679 c.-523T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1673685 c.-517C>T upstream_gene_variant 0.89 isoniazid
ethionamide
inhA 1673710 c.-492C>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673716 c.-486_-485delGCinsAA upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673733 c.-469G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673758 c.-444A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673916 c.-286A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673917 c.-285G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673922 c.-280T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673941 c.-261G>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673955 c.-247G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674342 c.141T>C synonymous_variant 0.9 isoniazid
ethionamide
inhA 1674352 p.Thr51Ala missense_variant 1.0 isoniazid
ethionamide Uncertain significance
inhA 1674357 c.156C>T synonymous_variant 0.91 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674367 p.Ala56Gln missense_variant 0.9 isoniazid
ethionamide
inhA 1674382 p.Leu61Ile missense_variant 1.0 isoniazid
ethionamide
inhA 1674471 c.270G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674489 c.288G>T synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674507 c.306G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674534 c.333G>C synonymous_variant 0.67 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674537 c.336C>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674540 c.339C>T synonymous_variant 0.67 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674588 c.387G>A synonymous_variant 0.77 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674601 p.Leu134Val missense_variant 1.0 isoniazid
ethionamide
inhA 1674618 c.417C>T synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674619 p.Pro140Ser missense_variant 0.8 isoniazid
ethionamide
inhA 1674624 c.423A>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674627 c.426T>C synonymous_variant 0.83 isoniazid
ethionamide
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 0.74 isoniazid
ethionamide
inhA 1674669 c.468G>C synonymous_variant 0.78 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 0.76 isoniazid
ethionamide
inhA 1674696 c.495G>A synonymous_variant 0.75 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674729 c.528G>A synonymous_variant 0.84 isoniazid
ethionamide
inhA 1674745 p.Tyr182Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674765 c.564C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674774 c.573A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674777 c.576C>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674820 c.619_621delCTCinsTTG synonymous_variant 0.89 isoniazid
ethionamide
inhA 1674828 c.627G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 1.0 isoniazid
ethionamide
inhA 1674870 c.669T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674876 c.675C>G synonymous_variant 0.73 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674888 c.687C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 1.0 isoniazid
ethionamide
inhA 1674909 c.708G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674915 c.714C>G synonymous_variant 0.66 isoniazid
ethionamide
inhA 1674939 c.738G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674942 c.741T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674954 c.753G>C synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674966 c.765T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674967 p.Asp256Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674993 c.792G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674994 p.His265Ser missense_variant 1.0 isoniazid
ethionamide
inhA 1675006 c.805_807delCTCinsTTG synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833256 c.-286C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833262 c.-280T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833273 c.-269G>A upstream_gene_variant 1.0 pyrazinamide
rpsA 1833277 c.-265C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833288 c.-254_-253delTGinsCC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833304 c.-238C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833319 c.-223C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833340 c.-202G>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833343 c.-199G>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833352 c.-190C>G upstream_gene_variant 1.0 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 0.81 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.81 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.83 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.78 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.77 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.74 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.69 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833895 c.354G>C synonymous_variant 0.72 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.73 pyrazinamide
rpsA 1833970 c.429G>A synonymous_variant 0.75 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.78 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 1.0 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.87 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.91 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.76 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 0.72 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.72 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.74 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834474 c.933C>T synonymous_variant 0.72 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.7 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.32 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.79 pyrazinamide
rpsA 1834603 c.1062G>A synonymous_variant 0.82 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 0.99 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 0.69 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.91 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
tsnR 1853369 c.-237C>T upstream_gene_variant 0.73 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>A upstream_gene_variant 0.73 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.73 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.73 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 0.73 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 0.8 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 1.0 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 0.75 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.75 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 1.0 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 1.0 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 1.0 linezolid
tsnR 1853493 c.-113G>A upstream_gene_variant 1.0 linezolid
tsnR 1853498 c.-108G>A upstream_gene_variant 1.0 linezolid
tsnR 1853507 c.-99G>A upstream_gene_variant 1.0 linezolid
tsnR 1853510 c.-96G>C upstream_gene_variant 1.0 linezolid
tsnR 1853522 c.-84C>G upstream_gene_variant 1.0 linezolid
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917975 c.36C>G synonymous_variant 0.64 capreomycin
tlyA 1917981 c.42G>C synonymous_variant 1.0 capreomycin
tlyA 1917990 c.51G>C synonymous_variant 0.5 capreomycin
tlyA 1917993 c.54A>G synonymous_variant 0.5 capreomycin Not assoc w R - Interim
tlyA 1917999 c.60T>C synonymous_variant 0.54 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 1.0 capreomycin
tlyA 1918008 c.69C>G synonymous_variant 0.62 capreomycin
tlyA 1918011 c.72G>C synonymous_variant 0.62 capreomycin
tlyA 1918029 c.90C>G synonymous_variant 0.65 capreomycin
tlyA 1918035 c.96G>C synonymous_variant 0.65 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 1.0 capreomycin
tlyA 1918047 c.108G>C synonymous_variant 0.79 capreomycin
tlyA 1918048 p.Leu37Met missense_variant 1.0 capreomycin
bacA 2064993 c.-265T>C upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101756 c.1287G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101768 c.1275C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101771 c.1272T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101774 c.1269T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101777 c.1266C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101795 c.1248G>C synonymous_variant 0.79 isoniazid
delamanid
ethionamide
ndh 2101804 c.1239T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101825 c.1218G>A synonymous_variant 0.82 isoniazid
delamanid
ethionamide
ndh 2101837 p.Ala402Val missense_variant 1.0 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 0.95 isoniazid
delamanid
ethionamide
ndh 2101873 c.1170T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101879 c.1164C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2101890 p.Val385Leu missense_variant 0.92 isoniazid
delamanid
ethionamide
ndh 2101988 p.Ala352Asp missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101990 c.1053G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2101993 c.1050A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102020 c.1023A>G synonymous_variant 0.9 isoniazid
delamanid
ethionamide
ndh 2102617 c.426C>T synonymous_variant 0.92 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102632 c.411C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102638 c.405A>G synonymous_variant 0.94 isoniazid
delamanid
ethionamide
ndh 2102644 c.399A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102671 c.372T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102674 c.369G>A synonymous_variant 0.91 isoniazid
delamanid
ethionamide
ndh 2102677 c.366C>G synonymous_variant 0.91 isoniazid
delamanid
ethionamide
ndh 2102683 c.360T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102686 c.357G>C synonymous_variant 0.84 isoniazid
delamanid
ethionamide
ndh 2102700 c.343C>T synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102711 p.Pro111Asp missense_variant 0.83 isoniazid
delamanid
ethionamide
ndh 2102718 p.Gln109Glu missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102878 c.165G>C synonymous_variant 0.92 isoniazid
delamanid
ethionamide
ndh 2102883 c.160C>T synonymous_variant 0.92 isoniazid
delamanid
ethionamide
ndh 2102895 c.148C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102902 c.141C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102908 c.135C>G synonymous_variant 0.96 isoniazid
delamanid
ethionamide
ndh 2102914 c.129C>T synonymous_variant 0.96 isoniazid
delamanid
ethionamide
ndh 2102919 c.124C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102938 p.Arg35His missense_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102959 c.84C>T synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102962 c.81A>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102971 c.72C>T synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102977 c.66T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
katG 2155026 c.1086C>G synonymous_variant 1.0 isoniazid
katG 2155047 c.1065C>G synonymous_variant 1.0 isoniazid
katG 2155054 p.Tyr353Phe missense_variant 1.0 isoniazid
katG 2155056 c.1056A>G synonymous_variant 1.0 isoniazid
katG 2155062 c.1050T>C synonymous_variant 1.0 isoniazid
katG 2155068 c.1044T>G synonymous_variant 1.0 isoniazid
katG 2155071 c.1041T>G synonymous_variant 1.0 isoniazid
katG 2155080 c.1032G>C synonymous_variant 1.0 isoniazid
katG 2155083 c.1029G>C synonymous_variant 1.0 isoniazid
katG 2155086 c.1026G>A synonymous_variant 1.0 isoniazid
katG 2155119 c.993T>C synonymous_variant 1.0 isoniazid
katG 2155131 c.981A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155587 c.525G>C synonymous_variant 1.0 isoniazid
katG 2155590 c.522A>G synonymous_variant 1.0 isoniazid
katG 2155614 c.498T>G synonymous_variant 1.0 isoniazid
katG 2155617 p.Ile165Leu missense_variant 1.0 isoniazid
katG 2155626 c.486G>C synonymous_variant 1.0 isoniazid
katG 2155632 c.480A>G synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155656 c.456G>A synonymous_variant 0.88 isoniazid
katG 2155661 p.Val151Ile missense_variant 1.0 isoniazid
katG 2155680 c.432G>C synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155695 c.417C>G synonymous_variant 1.0 isoniazid
katG 2155716 c.396T>C synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.4 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
katG 2155740 p.Gly124Gln missense_variant 1.0 isoniazid
katG 2155782 c.330C>G synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.74 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.72 isoniazid
kasA 2517965 c.-150C>T upstream_gene_variant 0.71 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.77 isoniazid
kasA 2517983 c.-132T>C upstream_gene_variant 0.8 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 1.0 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 1.0 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 1.0 isoniazid
kasA 2518040 c.-75G>T upstream_gene_variant 0.95 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 1.0 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 1.0 isoniazid
kasA 2518053 c.-62_-60delATTinsCTG upstream_gene_variant 1.0 isoniazid
kasA 2518132 c.18C>T synonymous_variant 1.0 isoniazid
kasA 2518138 c.24T>C synonymous_variant 1.0 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 1.0 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.75 isoniazid
kasA 2518162 c.48G>A synonymous_variant 1.0 isoniazid
kasA 2518169 p.Val19Leu missense_variant 0.73 isoniazid
kasA 2518172 p.Thr20Ala missense_variant 0.73 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 1.0 isoniazid
kasA 2518199 p.Ile29Val missense_variant 1.0 isoniazid
kasA 2518219 c.105T>C synonymous_variant 0.87 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.95 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 1.0 isoniazid
kasA 2518273 c.159G>A synonymous_variant 1.0 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518475 c.361A>C synonymous_variant 0.77 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518492 c.378C>T synonymous_variant 0.74 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.96 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.96 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.93 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.94 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.6 isoniazid
kasA 2518540 c.426T>C synonymous_variant 0.37 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.94 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.93 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.92 isoniazid
kasA 2518573 c.459G>C synonymous_variant 0.42 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.92 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.5 isoniazid
kasA 2518582 c.468G>C synonymous_variant 0.42 isoniazid
kasA 2518583 p.Gln157Glu missense_variant 0.42 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.5 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.5 isoniazid
kasA 2518594 c.480C>T synonymous_variant 0.44 isoniazid
kasA 2518597 c.483C>G synonymous_variant 0.44 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.54 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.96 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.32 isoniazid
kasA 2518636 c.522C>A synonymous_variant 0.42 isoniazid
kasA 2518639 c.525G>C synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.44 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.44 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.52 isoniazid
kasA 2518657 c.543G>C synonymous_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.5 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518681 c.567C>T synonymous_variant 0.5 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518687 p.Asp191Glu missense_variant 0.56 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.66 isoniazid
kasA 2518702 c.588C>T synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518717 c.603C>G synonymous_variant 0.66 isoniazid
kasA 2518723 c.609G>A synonymous_variant 0.71 isoniazid
kasA 2518735 c.621C>T synonymous_variant 0.73 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518768 c.654C>G synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>A synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.69 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.97 isoniazid
kasA 2518840 c.726C>G synonymous_variant 0.65 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.64 isoniazid
kasA 2518846 c.732G>C synonymous_variant 0.61 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.97 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.97 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.93 isoniazid
kasA 2518894 c.780G>A synonymous_variant 0.42 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.96 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518910 p.Leu266Met missense_variant 1.0 isoniazid
kasA 2518921 c.807T>C synonymous_variant 0.67 isoniazid
kasA 2518927 c.813C>G synonymous_variant 0.64 isoniazid
kasA 2519062 c.948T>G synonymous_variant 1.0 isoniazid
kasA 2519068 c.954C>T synonymous_variant 0.92 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 1.0 isoniazid
kasA 2519107 c.993T>C synonymous_variant 1.0 isoniazid
kasA 2519108 p.Asp332Gln missense_variant 0.8 isoniazid
kasA 2519116 c.1002C>G synonymous_variant 0.83 isoniazid
kasA 2519122 c.1008G>C synonymous_variant 0.86 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 1.0 isoniazid
kasA 2519140 c.1026G>A synonymous_variant 0.33 isoniazid
kasA 2519146 c.1032C>A synonymous_variant 0.48 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 0.52 isoniazid
kasA 2519158 c.1044C>T synonymous_variant 0.38 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 1.0 isoniazid
kasA 2519173 c.1059C>G synonymous_variant 0.37 isoniazid
kasA 2519194 c.1080G>T synonymous_variant 0.65 isoniazid
kasA 2519195 p.Thr361Cys missense_variant 0.65 isoniazid
kasA 2519203 c.1089C>G synonymous_variant 0.65 isoniazid
kasA 2519206 c.1092C>T synonymous_variant 0.65 isoniazid
kasA 2519209 c.1095C>T synonymous_variant 0.65 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 1.0 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 1.0 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 1.0 isoniazid
ahpC 2726591 c.399C>G synonymous_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726627 c.435G>A synonymous_variant 0.56 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 0.41 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 1.0 isoniazid
ahpC 2726654 c.462G>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
ahpC 2726657 c.465A>G synonymous_variant 1.0 isoniazid
ahpC 2726660 c.468C>T synonymous_variant 0.54 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 1.0 isoniazid
ahpC 2726672 c.480G>A synonymous_variant 0.42 isoniazid Not assoc w R - Interim
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 1.0 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 0.56 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 1.0 isoniazid
folC 2747032 c.567A>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747047 c.552C>T synonymous_variant 0.81 para-aminosalicylic_acid
folC 2747053 c.546C>T synonymous_variant 0.82 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 0.83 para-aminosalicylic_acid
folC 2747098 c.501C>G synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747132 p.Thr156Val missense_variant 0.77 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747137 c.462G>C synonymous_variant 0.77 para-aminosalicylic_acid
folC 2747293 c.306G>A synonymous_variant 0.8 para-aminosalicylic_acid
folC 2747302 c.297A>C synonymous_variant 0.83 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747335 c.264G>T synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2782450 c.1593C>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782453 c.1590C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782513 c.1530G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782522 c.1521G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782861 c.1182T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782864 c.1179T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782869 p.Ala392Thr missense_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2782876 c.1167G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782882 c.1161T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782936 c.1107G>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782990 c.1053C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783015 p.Ser343Thr missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783035 c.1008G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 1.0 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783048 p.Asp332Gly missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783101 c.942G>T synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783146 c.897G>A synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783182 c.861C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783185 c.858G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783197 c.846C>G synonymous_variant 0.89 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783221 c.822G>C synonymous_variant 0.75 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 0.92 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783235 c.808T>C synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783236 c.807G>A synonymous_variant 0.71 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783275 c.768C>G synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783314 c.729C>A synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783320 c.723C>T synonymous_variant 0.66 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783332 c.711T>C synonymous_variant 0.98 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783347 c.696C>G synonymous_variant 0.85 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.98 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.98 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.88 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.98 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.95 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.98 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783427 p.Pro206Ala missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin
Rv2477c 2783431 c.612C>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783437 c.606G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783458 c.585G>C synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 0.91 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783542 c.501G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783578 c.465G>A synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783602 c.441G>A synonymous_variant 0.87 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783623 c.420G>A synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783632 c.411C>G synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.76 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 0.73 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783766 p.Met93Leu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783788 c.255T>G synonymous_variant 0.67 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783794 c.249G>A synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 0.69 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783827 c.216C>T synonymous_variant 0.77 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 0.82 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 0.76 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783881 c.160_162delTTGinsCTC synonymous_variant 0.79 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783884 c.159T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783914 c.129T>C synonymous_variant 0.32 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783920 c.123G>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 0.7 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783968 c.75G>C synonymous_variant 0.74 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2784428 c.-386T>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784429 c.-387A>G upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784432 c.-390A>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784452 c.-410C>T upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784454 c.-412G>A upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784456 c.-414A>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784472 c.-430C>A upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2784477 c.-435T>C upstream_gene_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
pepQ 2859669 c.750T>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859678 c.741A>G synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859687 c.732C>T synonymous_variant 0.88 bedaquiline
clofazimine
pepQ 2859690 c.729C>G synonymous_variant 0.88 bedaquiline
clofazimine
pepQ 2859704 c.715T>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859708 c.711C>T synonymous_variant 0.88 bedaquiline
clofazimine
pepQ 2859723 c.696T>C synonymous_variant 1.0 bedaquiline
clofazimine Not assoc w R - Interim
pepQ 2859732 c.687C>T synonymous_variant 0.93 bedaquiline
clofazimine
pepQ 2859735 c.684G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859765 c.654G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859771 c.648T>C synonymous_variant 0.94 bedaquiline
clofazimine
pepQ 2859774 c.645C>T synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859778 p.Val214Asp missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859780 p.Gln213Ala missense_variant 1.0 bedaquiline
clofazimine
pepQ 2859783 c.636G>C synonymous_variant 1.0 bedaquiline
clofazimine
pepQ 2859791 p.Ala210Ser missense_variant 1.0 bedaquiline
clofazimine
pepQ 2860422 c.-4G>A upstream_gene_variant 1.0 bedaquiline
clofazimine
pepQ 2860424 c.-6A>T upstream_gene_variant 0.69 bedaquiline
clofazimine
pepQ 2860425 c.-7A>G upstream_gene_variant 0.69 bedaquiline
clofazimine
pepQ 2860446 c.-28T>A upstream_gene_variant 1.0 bedaquiline
clofazimine
pepQ 2860456 c.-38G>C upstream_gene_variant 1.0 bedaquiline
clofazimine
pepQ 2860467 c.-49G>C upstream_gene_variant 0.8 bedaquiline
clofazimine
pepQ 2860472 c.-54G>C upstream_gene_variant 0.8 bedaquiline
clofazimine
pepQ 2860475 c.-57C>T upstream_gene_variant 1.0 bedaquiline
clofazimine
pepQ 2860487 c.-69G>A upstream_gene_variant 0.76 bedaquiline
clofazimine
pepQ 2860490 c.-72G>C upstream_gene_variant 1.0 bedaquiline
clofazimine
pepQ 2860493 c.-75C>T upstream_gene_variant 0.85 bedaquiline
clofazimine
Rv2680 2996046 c.-59A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996058 c.-47C>A upstream_gene_variant 1.0 capreomycin
Rv2680 2996060 c.-45T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996061 c.-44C>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996084 c.-21A>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996097 c.-8A>G upstream_gene_variant 0.63 capreomycin
Rv2680 2996109 p.Thr2Asn missense_variant 1.0 capreomycin
Rv2680 2996111 p.Ser3Arg missense_variant 1.0 capreomycin
Rv2680 2996135 p.Ser11Gly missense_variant 1.0 capreomycin
Rv2681 2996957 c.219T>C synonymous_variant 1.0 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 1.0 capreomycin
Rv2681 2997011 c.273C>T synonymous_variant 0.95 capreomycin
Rv2681 2997013 p.Gly92Val missense_variant 1.0 capreomycin
Rv2681 2997021 c.283T>C synonymous_variant 1.0 capreomycin
Rv2681 2997028 p.Val97Ala missense_variant 1.0 capreomycin
Rv2681 2997033 p.Ala99Arg missense_variant 1.0 capreomycin
Rv2681 2997038 c.300G>C synonymous_variant 1.0 capreomycin
Rv2681 2997053 c.315C>G synonymous_variant 1.0 capreomycin
Rv2681 2997054 p.Ser106Gly missense_variant 1.0 capreomycin Uncertain significance
Rv2681 2997060 p.Asn108Asp missense_variant 1.0 capreomycin
Rv2681 2997078 p.Ser114Ala missense_variant 0.92 capreomycin Uncertain significance
Rv2752c 3064776 c.1416T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064783 p.Ser470Glu missense_variant 0.91 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064785 c.1407G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064790 c.1402T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064803 c.1389C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064815 c.1377T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064832 p.Ala454Thr missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064835 p.Ile453Val missense_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064838 c.1354T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064839 c.1353C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064860 c.1332G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064962 c.1230C>G synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064973 p.Ala407Ser missense_variant 0.33 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064974 c.1218T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064989 c.1203G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3064998 c.1194A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065040 c.1150_1152delCTCinsTTG synonymous_variant 0.98 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065049 c.1143G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065055 c.1137T>G synonymous_variant 0.97 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065061 c.1131C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065064 c.1128G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065070 c.1122C>A synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065073 c.1119C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065088 c.1104A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065097 c.1095C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065106 c.1086C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065109 c.1081_1083delAGAinsCGG synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065130 c.1062A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065133 c.1059T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065142 c.1050A>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.97 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065154 c.1038G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065174 c.1018C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065186 c.1006T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065190 p.Ile334Val missense_variant 0.98 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065199 c.993T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065202 c.990T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065205 c.987T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065210 c.982T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065223 c.969T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065229 c.963G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065232 c.960T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065235 c.957G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065241 c.951A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065262 c.930G>A synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065268 c.924A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065901 c.291A>G synonymous_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065916 c.276T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065919 c.273G>A synonymous_variant 0.81 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065922 c.270T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065946 p.Gly82Ala missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065949 c.243C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065957 c.235T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065963 c.229C>T synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3065997 c.195C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066006 c.186G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066017 c.175C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066024 c.168T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066040 p.Gly51Thr missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066042 c.150T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066050 p.Leu48Met missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066054 c.138T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066066 c.126T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066071 c.121T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066309 c.-118T>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066330 c.-139G>T upstream_gene_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066335 c.-144T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066336 c.-145C>T upstream_gene_variant 0.63 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066339 c.-148G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066350 c.-159T>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066351 c.-160G>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066354 c.-163G>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066365 c.-174C>T upstream_gene_variant 0.7 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066366 c.-175C>G upstream_gene_variant 0.7 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066387 c.-196G>A upstream_gene_variant 0.74 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066399 c.-210_-208delATTinsGTC upstream_gene_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066402 c.-211C>T upstream_gene_variant 0.78 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066420 c.-229C>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066423 c.-232C>T upstream_gene_variant 0.82 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066429 c.-238G>A upstream_gene_variant 0.88 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066432 c.-241T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066437 c.-246G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066459 c.-268T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066501 c.-310G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066513 c.-322C>G upstream_gene_variant 0.68 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066527 c.-336C>T upstream_gene_variant 0.75 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066543 c.-352C>A upstream_gene_variant 0.63 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066549 c.-358T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066560 c.-369C>T upstream_gene_variant 0.66 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066561 c.-370A>G upstream_gene_variant 0.34 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066567 c.-376C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066573 c.-382G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066583 c.-392C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066597 c.-406C>T upstream_gene_variant 0.77 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066603 c.-412A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066612 c.-421G>A upstream_gene_variant 0.81 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066647 c.-456G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066676 c.-485C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066687 c.-496G>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066696 c.-505T>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066707 c.-516A>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066807 c.-616T>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066810 c.-619G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066819 c.-628T>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
Rv2752c 3066822 c.-631T>C upstream_gene_variant 0.91 levofloxacin
moxifloxacin
isoniazid
rifampicin
ethambutol
thyX 3067301 c.645C>T synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067316 c.630A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067319 c.627G>T synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067325 c.621A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067337 c.609C>T synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067340 c.606G>A synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067358 c.588C>T synonymous_variant 0.87 para-aminosalicylic_acid
thyX 3067379 c.567C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 0.77 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067400 c.546C>G synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.7 para-aminosalicylic_acid
thyX 3067418 c.528C>G synonymous_variant 0.63 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.58 para-aminosalicylic_acid
thyX 3067430 c.516C>T synonymous_variant 0.53 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067442 c.504C>A synonymous_variant 0.42 para-aminosalicylic_acid
thyX 3067445 c.501C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067448 c.498G>A synonymous_variant 0.39 para-aminosalicylic_acid
thyX 3067454 c.492C>T synonymous_variant 0.38 para-aminosalicylic_acid
thyX 3067457 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067465 p.Ile161Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067475 c.471A>G synonymous_variant 0.62 para-aminosalicylic_acid
thyX 3067490 c.456C>G synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067493 c.453A>G synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067515 p.Ser144Thr missense_variant 1.0 para-aminosalicylic_acid
thyX 3067545 p.Glu134Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067565 p.Asp127Glu missense_variant 1.0 para-aminosalicylic_acid
thyX 3067570 p.Ala126Pro missense_variant 1.0 para-aminosalicylic_acid
thyX 3067577 c.369G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067583 c.363C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067601 p.Arg115His missense_variant 1.0 para-aminosalicylic_acid
thyX 3067611 p.Lys112Thr missense_variant 1.0 para-aminosalicylic_acid
thyX 3067619 c.327A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067631 c.315C>G synonymous_variant 0.63 para-aminosalicylic_acid
thyX 3067634 c.312C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067640 c.306G>A synonymous_variant 0.43 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067676 c.270C>G synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067679 p.Cys89Leu missense_variant 0.75 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067693 p.Ile85Val missense_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 1.0 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067841 c.105G>T synonymous_variant 0.46 para-aminosalicylic_acid
thyX 3067850 c.96A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067869 p.Thr26Ser missense_variant 1.0 para-aminosalicylic_acid
thyX 3067874 c.72C>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067877 c.69G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067883 p.Pro21Ser missense_variant 0.79 para-aminosalicylic_acid
thyX 3067886 c.60A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067889 c.57C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067898 p.Asp16Glu missense_variant 1.0 para-aminosalicylic_acid
thyA 3073770 p.Asp234His missense_variant 0.9 para-aminosalicylic_acid
thyA 3073776 c.696A>T synonymous_variant 0.9 para-aminosalicylic_acid
thyA 3073781 p.Leu231Phe missense_variant 0.9 para-aminosalicylic_acid
thyA 3073787 p.Lys229Glu missense_variant 0.93 para-aminosalicylic_acid
thyA 3073794 c.678A>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073818 p.Leu218Ile missense_variant 0.69 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073830 p.Glu214Asp missense_variant 0.6 para-aminosalicylic_acid
thyA 3073836 c.636C>T synonymous_variant 0.56 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073854 c.618C>T synonymous_variant 0.6 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073887 p.Ser195Asp missense_variant 0.64 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073944 c.528C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074070 c.402C>T synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3074172 c.300G>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074175 c.297A>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074181 c.291A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074187 c.285T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074205 p.Glu89Asp missense_variant 0.92 para-aminosalicylic_acid
thyA 3074214 c.258T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3074244 c.228A>G synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3074254 p.His73Arg missense_variant 0.78 para-aminosalicylic_acid
thyA 3074262 c.210T>C synonymous_variant 0.59 para-aminosalicylic_acid
thyA 3074267 p.Ile69Val missense_variant 0.95 para-aminosalicylic_acid
thyA 3074268 c.204T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3074297 c.175C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074301 c.171C>T synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074305 p.Ala56Val missense_variant 0.92 para-aminosalicylic_acid
thyA 3074307 c.165A>G synonymous_variant 0.92 para-aminosalicylic_acid
thyA 3074313 c.159A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074316 p.Phe52Leu missense_variant 0.93 para-aminosalicylic_acid
thyA 3074322 c.150C>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074325 c.147A>G synonymous_variant 0.93 para-aminosalicylic_acid
thyA 3074334 c.138T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074337 c.135C>G synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074360 c.112T>C synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3074361 c.111T>C synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074364 c.108T>C synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3074372 p.Met34Leu missense_variant 0.9 para-aminosalicylic_acid
thyA 3074373 c.99G>A synonymous_variant 0.8 para-aminosalicylic_acid
thyA 3074397 c.75A>G synonymous_variant 0.54 para-aminosalicylic_acid
ald 3087653 c.834A>G synonymous_variant 1.0 cycloserine
ald 3087659 c.840G>C synonymous_variant 0.87 cycloserine
ald 3087672 p.His285Asp missense_variant 1.0 cycloserine
ald 3087686 c.867C>G synonymous_variant 0.75 cycloserine
ald 3087692 c.873C>T synonymous_variant 0.68 cycloserine
ald 3087699 p.Leu294Met missense_variant 0.68 cycloserine
ald 3087726 p.Ala303Ser missense_variant 1.0 cycloserine
ald 3087729 p.Ser304Ala missense_variant 1.0 cycloserine
ald 3087734 c.915G>T synonymous_variant 0.61 cycloserine
ald 3087737 c.918G>C synonymous_variant 0.39 cycloserine
ald 3087743 c.924G>C synonymous_variant 0.61 cycloserine
ald 3087749 c.930C>G synonymous_variant 0.36 cycloserine
ald 3087750 p.Tyr311Val missense_variant 0.36 cycloserine
ald 3087761 c.942C>G synonymous_variant 1.0 cycloserine
ald 3087770 c.951G>C synonymous_variant 1.0 cycloserine
lpqB 3623363 c.1548T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3623388 p.Thr508Asn missense_variant 0.8 rifampicin
bedaquiline
lpqB 3623424 p.Ser496Tyr missense_variant 0.8 rifampicin
bedaquiline
lpqB 3623987 c.924G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624008 c.903T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624023 c.888G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624032 c.879T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624035 c.874_876delAGGinsCGA synonymous_variant 0.94 rifampicin
bedaquiline
lpqB 3624041 p.Glu290Asp missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624050 c.861C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624053 c.858C>G synonymous_variant 0.8 rifampicin
bedaquiline
lpqB 3624061 p.Ala284Thr missense_variant 0.78 rifampicin
bedaquiline
lpqB 3624077 c.834G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624086 c.825C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624092 c.817_819delAGGinsCGA synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624100 c.811T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624101 c.810C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624107 c.804C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624113 c.798G>A synonymous_variant 0.59 rifampicin
bedaquiline
lpqB 3624116 c.795A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624119 c.792C>G synonymous_variant 0.38 rifampicin
bedaquiline
lpqB 3624124 p.Leu263Val missense_variant 0.34 rifampicin
bedaquiline
lpqB 3624125 c.786A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624152 c.759C>G synonymous_variant 0.61 rifampicin
bedaquiline
lpqB 3624163 p.Glu250Gln missense_variant 0.58 rifampicin
bedaquiline
lpqB 3624166 p.Met249Leu missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624167 c.744C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624172 p.Val247Ile missense_variant 0.68 rifampicin
bedaquiline
lpqB 3624173 c.738A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624188 c.723G>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624194 c.717C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624199 p.Ile238Val missense_variant 0.65 rifampicin
bedaquiline
lpqB 3624200 c.711A>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624209 c.702A>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624221 c.690G>C synonymous_variant 0.68 rifampicin
bedaquiline
lpqB 3624224 c.687T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624371 c.540T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624377 c.534C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624389 c.522C>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624419 c.492C>T synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624422 c.489G>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624635 c.276C>T synonymous_variant 0.79 rifampicin
bedaquiline
lpqB 3624646 c.265T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624649 c.262T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624652 p.Ala87Ser missense_variant 0.69 rifampicin
bedaquiline
lpqB 3624656 c.255C>T synonymous_variant 0.69 rifampicin
bedaquiline
lpqB 3624671 p.Ala80Ser missense_variant 0.71 rifampicin
bedaquiline
lpqB 3624749 c.162G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3624755 c.154_156delTTAinsCTG synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624770 c.141T>C synonymous_variant 0.69 rifampicin
bedaquiline
lpqB 3624776 c.135T>C synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624783 p.Ser43Thr missense_variant 1.0 rifampicin
bedaquiline
lpqB 3624788 c.123A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3624797 c.114T>C synonymous_variant 0.64 rifampicin
bedaquiline
lpqB 3625027 c.-117C>G upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3625032 c.1582C>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625054 c.-144C>T upstream_gene_variant 0.86 rifampicin
bedaquiline
lpqB 3625057 c.-147C>T upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3625065 p.Met517Leu missense_variant 1.0 rifampicin Not assoc w R
bedaquiline Uncertain significance
lpqB 3625066 c.-156G>A upstream_gene_variant 0.84 rifampicin
bedaquiline
lpqB 3625069 c.-159T>G upstream_gene_variant 0.94 rifampicin
bedaquiline
lpqB 3625084 c.-174C>T upstream_gene_variant 0.83 rifampicin
bedaquiline
mtrB 3625095 p.Glu507Gln missense_variant 0.82 rifampicin
bedaquiline
lpqB 3625096 c.-186C>T upstream_gene_variant 0.82 rifampicin
bedaquiline
lpqB 3625117 c.-207T>G upstream_gene_variant 0.93 rifampicin
bedaquiline
lpqB 3625123 c.-213T>C upstream_gene_variant 0.94 rifampicin
bedaquiline
lpqB 3625138 c.-228C>G upstream_gene_variant 0.95 rifampicin
bedaquiline
lpqB 3625147 c.-237C>G upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3625162 c.1452T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 0.65 rifampicin
bedaquiline
lpqB 3625186 c.-276T>C upstream_gene_variant 0.96 rifampicin
bedaquiline
mtrB 3625189 c.1425A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625195 c.-285A>G upstream_gene_variant 0.96 rifampicin
bedaquiline
lpqB 3625198 c.-288C>G upstream_gene_variant 0.65 rifampicin
bedaquiline
lpqB 3625201 c.-291T>C upstream_gene_variant 0.95 rifampicin
bedaquiline
lpqB 3625207 c.-297C>G upstream_gene_variant 0.67 rifampicin
bedaquiline
lpqB 3625213 c.-303C>T upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3625222 c.1392T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625234 c.-324G>A upstream_gene_variant 0.75 rifampicin
bedaquiline
lpqB 3625240 c.-330T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625537 c.-627T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625543 c.-633G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625569 c.1045T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625572 p.Thr348Ser missense_variant 0.87 rifampicin
bedaquiline
lpqB 3625579 c.-669A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625594 c.-684T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625602 c.-692T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625612 c.-702G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625624 c.-714C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625636 p.Ala326Glu missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625648 c.-738T>C upstream_gene_variant 0.61 rifampicin
bedaquiline
mtrB 3625656 c.958T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625675 c.-765G>C upstream_gene_variant 0.74 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625690 c.-780T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625696 c.-786A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625699 c.915C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625717 c.-807C>T upstream_gene_variant 0.8 rifampicin
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625755 p.Ala287Thr missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 0.73 rifampicin
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625783 c.-873C>T upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3625797 p.Val273Met missense_variant 0.32 rifampicin Uncertain significance
bedaquiline Uncertain significance
lpqB 3625801 c.-891G>C upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3625806 c.808A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625849 c.-939T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625852 c.762A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625867 c.747A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625870 c.-960C>G upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3625876 c.738G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625909 c.-999T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625912 c.702G>C synonymous_variant 0.83 rifampicin
bedaquiline
mtrB 3625915 c.699G>C synonymous_variant 0.83 rifampicin
bedaquiline
mtrB 3626353 c.261C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626362 c.252A>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626368 c.246G>A synonymous_variant 0.71 rifampicin
bedaquiline
mtrB 3626377 p.Asp79Glu missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626383 p.Ala77Gly missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626389 p.Arg75Lys missense_variant 0.82 rifampicin
bedaquiline
mtrB 3626400 p.Ile72Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626404 c.210C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626407 c.207C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626437 c.177T>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626443 c.171T>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626455 c.159C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626461 c.153A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626470 c.144A>C synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626473 c.141T>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626476 c.138C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626488 c.126C>G synonymous_variant 1.0 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626711 c.-98T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.41 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 0.42 rifampicin
bedaquiline
mtrB 3626750 c.-137T>C upstream_gene_variant 0.59 rifampicin
bedaquiline
mtrA 3626759 c.591T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626773 c.-160C>T upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGC upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626777 c.573C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 0.52 rifampicin
bedaquiline
mtrB 3626783 c.-170C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626786 c.564A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626792 c.558G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3626825 c.525T>A synonymous_variant 0.7 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626843 c.-230G>A upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626849 c.-236C>T upstream_gene_variant 0.66 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626903 c.-290T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626912 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626924 c.-311G>C upstream_gene_variant 0.62 rifampicin
bedaquiline
mtrB 3626927 c.-314G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626930 c.-317A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626933 c.-320C>T upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3626942 c.-329A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626954 c.-341C>G upstream_gene_variant 0.72 rifampicin
bedaquiline
mtrB 3626957 c.-344G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626969 c.-356C>G upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626996 c.-383G>A upstream_gene_variant 0.89 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627023 c.-410C>G upstream_gene_variant 0.79 rifampicin
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrA 3627068 c.282T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627101 c.-488C>G upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627110 c.-497G>C upstream_gene_variant 0.71 rifampicin
bedaquiline
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627128 c.-515T>C upstream_gene_variant 0.7 rifampicin
bedaquiline
mtrB 3627137 c.-526_-524delTTGinsCTA upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrB 3627143 c.-530G>C upstream_gene_variant 0.63 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627197 c.-584T>C upstream_gene_variant 0.59 rifampicin
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 0.56 rifampicin
bedaquiline
mtrB 3627209 c.-596G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627212 c.-599C>T upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrB 3627218 c.-605G>C upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrA 3627221 c.129C>T synonymous_variant 0.41 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627227 c.123T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627233 c.-620T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627239 c.111C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrA 3627242 c.108C>T synonymous_variant 0.46 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627254 c.-641C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627263 c.-650C>T upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627272 c.-659G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627275 c.-662G>T upstream_gene_variant 0.44 rifampicin
bedaquiline
mtrB 3627278 c.-665G>T upstream_gene_variant 0.58 rifampicin
bedaquiline
mtrB 3627287 c.-674C>G upstream_gene_variant 0.64 rifampicin
bedaquiline
mtrB 3627296 c.-683T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627299 c.-688_-686delTTGinsCTC upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627343 p.Thr3Ser missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627359 c.-746T>G upstream_gene_variant 0.88 rifampicin
bedaquiline
mtrB 3627360 c.-747G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
fbiB 3642662 c.1128C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3642668 c.1134A>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3642677 c.1143A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3642680 c.1146A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3642683 c.1149C>G synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiB 3642695 c.1161G>C synonymous_variant 0.82 pretomanid
delamanid
clofazimine
fbiB 3642707 c.1173C>G synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fbiB 3642710 c.1176G>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiB 3642711 p.Leu393Val missense_variant 0.79 pretomanid
delamanid
clofazimine
fbiB 3642743 c.1209T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiB 3642749 c.1215T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
alr 3840989 c.432G>C synonymous_variant 1.0 cycloserine
alr 3840994 p.His143Asp missense_variant 1.0 cycloserine
alr 3840997 c.424T>C synonymous_variant 1.0 cycloserine
alr 3841001 c.420A>G synonymous_variant 1.0 cycloserine
alr 3841013 c.408C>G synonymous_variant 0.92 cycloserine
alr 3841018 p.Leu135Val missense_variant 1.0 cycloserine
alr 3841033 p.Val130Ile missense_variant 1.0 cycloserine
alr 3841036 p.Gln129Glu missense_variant 0.92 cycloserine
alr 3841037 c.384G>C synonymous_variant 1.0 cycloserine
alr 3841055 c.366C>G synonymous_variant 0.92 cycloserine
alr 3841079 c.342T>C synonymous_variant 1.0 cycloserine
alr 3841088 c.333C>T synonymous_variant 0.92 cycloserine
alr 3841100 c.321A>T synonymous_variant 1.0 cycloserine
alr 3841106 c.315T>C synonymous_variant 1.0 cycloserine
alr 3841112 p.Asp103Ala missense_variant 1.0 cycloserine
alr 3841115 c.306T>G synonymous_variant 1.0 cycloserine
alr 3841124 c.297G>A synonymous_variant 0.94 cycloserine
alr 3841127 c.294A>G synonymous_variant 1.0 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 1.0 rifampicin
rpoA 3877506 p.Gly334Ala missense_variant 0.71 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoA 3877587 c.921A>C synonymous_variant 1.0 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.62 rifampicin
rpoA 3877638 c.870T>G synonymous_variant 0.65 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.35 rifampicin
rpoA 3877677 p.Ala277Cys missense_variant 0.57 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoA 3877685 c.823C>T synonymous_variant 0.57 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877731 c.777G>T synonymous_variant 0.65 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.66 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877758 c.750G>C synonymous_variant 0.63 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.33 rifampicin
rpoA 3877815 c.693C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877851 c.657C>T synonymous_variant 0.72 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877865 c.643C>T synonymous_variant 0.64 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877878 c.630G>C synonymous_variant 0.34 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.67 rifampicin
rpoA 3877890 c.618C>T synonymous_variant 0.33 rifampicin
rpoA 3877896 c.612G>C synonymous_variant 0.32 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877968 c.540C>G synonymous_variant 0.75 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.67 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 1.0 rifampicin
rpoA 3878040 c.468T>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>C synonymous_variant 0.66 rifampicin
rpoA 3878046 c.462T>G synonymous_variant 0.61 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 1.0 rifampicin
rpoA 3878058 c.450G>T synonymous_variant 0.33 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 1.0 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 1.0 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 1.0 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.52 rifampicin
rpoA 3878094 c.414C>G synonymous_variant 0.55 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 0.45 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 1.0 rifampicin
rpoA 3878141 p.Met123Leu missense_variant 0.42 rifampicin Uncertain significance
rpoA 3878143 p.Gly122Asp missense_variant 0.42 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.52 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878163 c.345C>T synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoA 3878166 c.342C>G synonymous_variant 0.67 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878226 c.282C>G synonymous_variant 0.42 rifampicin
rpoA 3878229 c.279C>G synonymous_variant 0.54 rifampicin
rpoA 3878232 c.276G>C synonymous_variant 0.46 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Ala missense_variant 0.38 rifampicin
rpoA 3878292 c.216T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 1.0 rifampicin
rpoA 3878310 c.198G>C synonymous_variant 0.4 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>C synonymous_variant 1.0 rifampicin
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.73 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 1.0 rifampicin
rpoA 3878384 c.124C>T synonymous_variant 0.69 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878415 c.93C>T synonymous_variant 1.0 rifampicin
rpoA 3878418 c.90C>T synonymous_variant 0.75 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 1.0 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 0.86 rifampicin
rpoA 3878471 p.Val13Leu missense_variant 0.88 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 1.0 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 1.0 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 1.0 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 1.0 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878701 c.-194C>G upstream_gene_variant 0.54 rifampicin
rpoA 3878713 c.-206G>C upstream_gene_variant 0.4 rifampicin
rpoA 3878716 c.-209C>G upstream_gene_variant 0.6 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878736 c.-229A>G upstream_gene_variant 0.62 rifampicin
rpoA 3878737 c.-230G>C upstream_gene_variant 0.62 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878749 c.-242G>T upstream_gene_variant 0.65 rifampicin
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878785 c.-278T>C upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878797 c.-290G>C upstream_gene_variant 0.74 rifampicin
rpoA 3878803 c.-296G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878806 c.-299C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878809 c.-302T>C upstream_gene_variant 0.94 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878836 c.-331_-329delAAGinsGGC upstream_gene_variant 1.0 rifampicin
rpoA 3878842 c.-335G>C upstream_gene_variant 0.44 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878869 c.-362G>C upstream_gene_variant 0.6 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 0.64 rifampicin
rpoA 3878884 c.-377C>G upstream_gene_variant 0.35 rifampicin
rpoA 3878889 c.-382A>G upstream_gene_variant 0.6 rifampicin
rpoA 3878894 c.-387A>G upstream_gene_variant 0.62 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878917 c.-410G>A upstream_gene_variant 0.37 rifampicin Uncertain significance
rpoA 3878920 c.-413C>T upstream_gene_variant 0.37 rifampicin
rpoA 3878923 c.-417_-416delGCinsCG upstream_gene_variant 0.6 rifampicin
rpoA 3878935 c.-428C>T upstream_gene_variant 0.39 rifampicin
rpoA 3878938 c.-431T>G upstream_gene_variant 0.37 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878953 c.-446C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878956 c.-449G>T upstream_gene_variant 0.52 rifampicin
rpoA 3878962 c.-455G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGTG upstream_gene_variant 1.0 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879037 c.-530G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879049 c.-542A>G upstream_gene_variant 0.49 rifampicin
rpoA 3879061 c.-554C>T upstream_gene_variant 0.49 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879117 c.-610C>T upstream_gene_variant 0.71 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879145 c.-638G>C upstream_gene_variant 0.77 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 0.78 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879178 c.-671T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879208 c.-701C>G upstream_gene_variant 0.78 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 1.0 rifampicin
ddn 3986630 c.-214C>G upstream_gene_variant 0.72 pretomanid
delamanid
ddn 3986636 c.-208C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986665 c.-179G>C upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986681 c.-163C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986690 c.-154C>G upstream_gene_variant 1.0 pretomanid
delamanid
ddn 3986696 c.-148G>C upstream_gene_variant 1.0 pretomanid
delamanid
clpC1 4038278 c.2427T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038329 p.Glu792Asp missense_variant 0.69 pyrazinamide
clpC1 4038338 c.2367C>T synonymous_variant 0.73 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 0.78 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038425 c.2280C>A synonymous_variant 0.83 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 1.0 pyrazinamide
clpC1 4038491 c.2214C>T synonymous_variant 0.91 pyrazinamide
clpC1 4038502 p.Ile735Val missense_variant 0.85 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 0.83 pyrazinamide
clpC1 4038518 c.2187G>T synonymous_variant 0.78 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038537 p.Thr723Ser missense_variant 0.74 pyrazinamide
clpC1 4038539 c.2166G>C synonymous_variant 0.73 pyrazinamide
clpC1 4038569 c.2136C>T synonymous_variant 0.75 pyrazinamide
clpC1 4038575 c.2130C>G synonymous_variant 0.73 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038620 c.2085G>A synonymous_variant 0.7 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038668 c.2037G>C synonymous_variant 0.7 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038677 c.2028G>C synonymous_variant 0.69 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038692 c.2013C>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4038701 c.2004G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.78 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4038809 c.1896G>A synonymous_variant 0.8 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 0.74 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038884 c.1821C>T synonymous_variant 0.74 pyrazinamide
clpC1 4038893 c.1812C>T synonymous_variant 0.74 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039025 c.1680C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.8 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.82 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039119 c.1585_1586delTCinsAG synonymous_variant 0.64 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.7 pyrazinamide
clpC1 4039193 c.1512C>G synonymous_variant 0.72 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 0.67 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 0.67 pyrazinamide
clpC1 4039243 c.1462C>T synonymous_variant 0.66 pyrazinamide
clpC1 4039259 c.1446G>A synonymous_variant 0.71 pyrazinamide
clpC1 4039262 c.1443C>T synonymous_variant 0.72 pyrazinamide Not assoc w R - Interim
clpC1 4039268 c.1437C>T synonymous_variant 0.75 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 0.78 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.76 pyrazinamide
clpC1 4039319 p.Ala462Thr missense_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 0.82 pyrazinamide
clpC1 4039382 c.1323C>T synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>A synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.62 pyrazinamide
clpC1 4039480 c.1225C>A synonymous_variant 0.28 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039526 c.1179G>A synonymous_variant 0.76 pyrazinamide
clpC1 4039532 c.1173C>T synonymous_variant 0.77 pyrazinamide
clpC1 4039553 c.1152C>A synonymous_variant 0.78 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039576 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039583 c.1122C>T synonymous_variant 0.81 pyrazinamide
clpC1 4039601 c.1104G>A synonymous_variant 0.87 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.97 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.72 pyrazinamide
clpC1 4039693 c.1012C>T synonymous_variant 0.58 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.96 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.95 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.5 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.43 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.42 pyrazinamide
clpC1 4039748 c.957G>A synonymous_variant 0.41 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.69 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.71 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039790 c.915C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039805 c.900C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>T synonymous_variant 0.7 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.63 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039949 p.Leu252Phe missense_variant 0.61 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039955 c.750G>T synonymous_variant 0.64 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.66 pyrazinamide
clpC1 4039964 c.741C>T synonymous_variant 0.69 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.31 pyrazinamide
clpC1 4040000 c.705C>T synonymous_variant 0.67 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040195 c.510G>T synonymous_variant 0.67 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.55 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040309 c.396C>T synonymous_variant 0.89 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.89 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.88 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.86 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040419 c.286C>T synonymous_variant 0.7 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>T synonymous_variant 0.31 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.63 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.64 pyrazinamide
clpC1 4040495 c.210C>A synonymous_variant 0.64 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040525 c.180C>T synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 1.0 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.83 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040588 c.117T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCTG synonymous_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040627 c.78C>T synonymous_variant 0.9 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040662 c.43C>T synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4040669 c.36C>G synonymous_variant 0.91 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 1.0 pyrazinamide
panD 4043867 p.Gly139Arg missense_variant 1.0 pyrazinamide Uncertain significance
panD 4044096 c.186C>T synonymous_variant 0.54 pyrazinamide
panD 4044120 c.162A>G synonymous_variant 1.0 pyrazinamide
panD 4044123 c.159T>C synonymous_variant 1.0 pyrazinamide
panD 4044126 c.156T>C synonymous_variant 1.0 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 1.0 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
panD 4044159 c.123C>T synonymous_variant 0.77 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 0.8 pyrazinamide
panD 4044165 c.117G>A synonymous_variant 1.0 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044180 c.102C>T synonymous_variant 0.89 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 1.0 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044225 c.57C>T synonymous_variant 0.9 pyrazinamide
panD 4044231 p.Cys17Gln missense_variant 1.0 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 1.0 pyrazinamide
panD 4044264 c.18G>C synonymous_variant 0.84 pyrazinamide
panD 4044719 c.-438G>A upstream_gene_variant 0.7 pyrazinamide
panD 4044722 c.-441G>A upstream_gene_variant 0.7 pyrazinamide
panD 4044737 c.-456T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044749 c.-468G>A upstream_gene_variant 0.47 pyrazinamide
panD 4044752 c.-471T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044779 c.-500_-498delCTAinsTGC upstream_gene_variant 1.0 pyrazinamide
panD 4044788 c.-507G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044791 c.-510G>C upstream_gene_variant 1.0 pyrazinamide
panD 4044800 c.-519C>G upstream_gene_variant 0.57 pyrazinamide
panD 4044812 c.-531A>C upstream_gene_variant 0.81 pyrazinamide
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 1.0 pyrazinamide
panD 4044823 c.-542G>C upstream_gene_variant 0.82 pyrazinamide
panD 4044844 c.-563T>C upstream_gene_variant 1.0 pyrazinamide
panD 4044953 c.-674_-672delCCGinsATT upstream_gene_variant 0.64 pyrazinamide
panD 4044956 c.-675C>G upstream_gene_variant 0.67 pyrazinamide
panD 4044962 c.-681C>G upstream_gene_variant 0.6 pyrazinamide
panD 4044965 c.-684T>C upstream_gene_variant 0.67 pyrazinamide
panD 4044977 c.-696T>C upstream_gene_variant 0.59 pyrazinamide
panD 4044989 c.-708T>C upstream_gene_variant 0.37 pyrazinamide
panD 4045000 c.-719A>T upstream_gene_variant 1.0 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045022 c.-742_-741delTCinsCG upstream_gene_variant 1.0 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045034 c.-753A>G upstream_gene_variant 1.0 pyrazinamide
panD 4045052 c.-771G>C upstream_gene_variant 0.6 pyrazinamide
panD 4045055 c.-774T>G upstream_gene_variant 0.39 pyrazinamide
panD 4045063 c.-782T>C upstream_gene_variant 0.57 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 1.0 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 1.0 pyrazinamide
panD 4045073 c.-792C>G upstream_gene_variant 0.64 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 1.0 pyrazinamide
glpK 4138535 c.1221T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138550 c.1206C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138568 c.1188A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138574 c.1182G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138580 c.1176C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138583 c.1173G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138596 p.Phe387Tyr missense_variant 0.81 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138598 c.1158G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138631 c.1125C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138640 c.1116C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138643 c.1113A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138670 c.1086G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138681 p.Met359Val missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138682 c.1074C>G synonymous_variant 0.61 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138695 p.Pro354His missense_variant 0.33 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138702 p.Gln352Glu missense_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138703 c.1053C>T synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138706 c.1050C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138714 p.Ala348Ser missense_variant 0.54 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138715 c.1041G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138721 c.1035G>A synonymous_variant 0.38 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138724 c.1032A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>G synonymous_variant 0.36 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138751 c.1005T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138763 c.993G>A synonymous_variant 0.41 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138769 c.987G>C synonymous_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138774 p.Ser328Ala missense_variant 0.42 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138778 c.978C>G synonymous_variant 0.43 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138796 c.960A>G synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139120 p.Asp212Glu missense_variant 0.5 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139132 c.624A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139143 c.613T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139150 c.606G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139156 c.600C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139165 c.591A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139168 c.588T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139176 p.Val194Ile missense_variant 0.65 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139177 c.579T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139183 c.573T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139186 c.570G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4139215 c.541T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139223 p.Thr178Ser missense_variant 0.9 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139230 p.Pro176Ala missense_variant 0.83 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139231 c.525A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139243 c.513A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139561 c.195G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139575 p.Val61Ile missense_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139579 c.177C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139588 c.168G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139597 c.159C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139601 p.Arg52Gln missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139609 p.Ile49Val missense_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139633 c.123C>T synonymous_variant 0.71 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139651 p.His35Gly missense_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139657 c.99T>C synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
embC 4239111 c.-752G>A upstream_gene_variant 1.0 ethambutol
embC 4239141 c.-722G>A upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239146 c.-717A>G upstream_gene_variant 1.0 ethambutol Uncertain significance
embC 4239147 c.-716T>C upstream_gene_variant 1.0 ethambutol
embC 4239161 c.-702A>G upstream_gene_variant 1.0 ethambutol
embC 4239173 c.-690T>C upstream_gene_variant 1.0 ethambutol
embC 4239176 c.-687C>G upstream_gene_variant 1.0 ethambutol
embC 4239336 c.-527T>C upstream_gene_variant 1.0 ethambutol
embC 4240471 c.609C>T synonymous_variant 1.0 ethambutol
embC 4240475 p.Ala205Ser missense_variant 1.0 ethambutol Uncertain significance
embC 4240489 c.627A>C synonymous_variant 1.0 ethambutol
embC 4240490 p.Pro210Ala missense_variant 1.0 ethambutol Uncertain significance
embC 4240495 c.633T>C synonymous_variant 1.0 ethambutol
embC 4240512 p.Ser217Thr missense_variant 1.0 ethambutol
embC 4240516 c.654G>C synonymous_variant 1.0 ethambutol
embC 4240519 c.657T>C synonymous_variant 1.0 ethambutol
embC 4240525 c.663C>G synonymous_variant 0.89 ethambutol
embC 4240657 c.795G>C synonymous_variant 0.65 ethambutol
embC 4240660 c.798C>G synonymous_variant 0.59 ethambutol
embC 4240669 c.807G>C synonymous_variant 0.33 ethambutol
embC 4240671 p.Thr270Ile missense_variant 1.0 ethambutol Not assoc w R
embC 4240678 c.816T>C synonymous_variant 1.0 ethambutol
embC 4240681 c.819G>C synonymous_variant 0.61 ethambutol
embC 4240685 p.Thr275Ala missense_variant 1.0 ethambutol
embC 4240690 c.828G>C synonymous_variant 0.58 ethambutol
embC 4240693 c.831T>C synonymous_variant 1.0 ethambutol
embC 4240698 p.Ala279Gly missense_variant 0.58 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.98 ethambutol Not assoc w R - Interim
embC 4240729 c.867C>G synonymous_variant 0.52 ethambutol
embC 4240747 c.885C>T synonymous_variant 0.42 ethambutol Not assoc w R - Interim
embC 4240759 c.897C>G synonymous_variant 0.41 ethambutol
embC 4240765 c.903C>G synonymous_variant 0.43 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.61 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240795 c.933C>G synonymous_variant 0.36 ethambutol
embC 4240819 c.957A>G synonymous_variant 1.0 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.62 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240867 c.1005T>C synonymous_variant 1.0 ethambutol
embC 4240870 c.1008T>C synonymous_variant 1.0 ethambutol
embC 4240873 c.1011C>G synonymous_variant 1.0 ethambutol
embC 4241038 c.1176G>C synonymous_variant 1.0 ethambutol
embC 4241044 c.1182C>T synonymous_variant 0.56 ethambutol
embC 4241047 c.1185C>G synonymous_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241053 c.1191G>C synonymous_variant 1.0 ethambutol
embC 4241059 c.1197G>A synonymous_variant 0.52 ethambutol
embC 4241071 c.1209C>G synonymous_variant 0.53 ethambutol
embC 4241086 c.1224G>C synonymous_variant 0.59 ethambutol
embC 4241089 c.1227C>G synonymous_variant 0.38 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241101 c.1239G>C synonymous_variant 0.67 ethambutol
embC 4241107 c.1245G>C synonymous_variant 0.35 ethambutol
embC 4241121 p.Ser420Asn missense_variant 0.69 ethambutol
embC 4241137 c.1275G>C synonymous_variant 0.67 ethambutol
embC 4241146 c.1284C>G synonymous_variant 1.0 ethambutol
embC 4241153 p.Ile431Val missense_variant 0.69 ethambutol Uncertain significance
embC 4241158 c.1296T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embC 4241185 c.1323G>C synonymous_variant 0.71 ethambutol
embC 4241188 c.1326C>T synonymous_variant 0.69 ethambutol
embC 4241194 c.1332C>G synonymous_variant 0.64 ethambutol
embC 4241197 c.1335G>C synonymous_variant 0.64 ethambutol
embC 4241200 c.1338C>T synonymous_variant 0.64 ethambutol
embC 4241203 c.1341T>C synonymous_variant 1.0 ethambutol
embC 4241206 c.1344G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241453 p.Ile531Val missense_variant 0.67 ethambutol
embA 4242739 c.-494C>G upstream_gene_variant 1.0 ethambutol
embA 4242742 c.-491C>G upstream_gene_variant 0.73 ethambutol
embA 4242748 c.-485A>G upstream_gene_variant 1.0 ethambutol
embA 4242754 c.-479G>C upstream_gene_variant 0.78 ethambutol
embC 4242764 p.Val968Leu missense_variant 1.0 ethambutol
embC 4242779 p.Asn973Asp missense_variant 1.0 ethambutol
embA 4245056 c.1824C>G synonymous_variant 0.83 ethambutol
embA 4245060 c.1828T>C synonymous_variant 1.0 ethambutol
embA 4245063 c.1831C>T synonymous_variant 0.75 ethambutol
embA 4245078 p.Trp616Val missense_variant 0.7 ethambutol
embA 4245083 c.1851A>C synonymous_variant 1.0 ethambutol
embA 4245089 c.1857G>C synonymous_variant 1.0 ethambutol
embA 4245093 p.Ile621Val missense_variant 0.73 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245125 c.1893G>A synonymous_variant 0.69 ethambutol Not assoc w R - Interim
embA 4245137 c.1905T>C synonymous_variant 1.0 ethambutol
embA 4245146 c.1914G>A synonymous_variant 0.46 ethambutol
embA 4245149 c.1917C>G synonymous_variant 1.0 ethambutol
embA 4245153 p.Ile641Val missense_variant 0.61 ethambutol
embA 4245182 c.1950T>C synonymous_variant 1.0 ethambutol
embA 4245189 c.1957C>T synonymous_variant 1.0 ethambutol
embA 4245198 p.Leu656Ile missense_variant 1.0 ethambutol
embA 4245207 c.1975T>C synonymous_variant 1.0 ethambutol
embA 4245215 c.1983A>C synonymous_variant 1.0 ethambutol
embA 4245222 p.Tyr664Gln missense_variant 1.0 ethambutol
embA 4245248 c.2016G>C synonymous_variant 0.62 ethambutol
embA 4245257 c.2025A>G synonymous_variant 1.0 ethambutol
embA 4245446 c.2214C>T synonymous_variant 1.0 ethambutol
embA 4245453 p.Ala741Thr missense_variant 1.0 ethambutol
embA 4245461 c.2229C>A synonymous_variant 1.0 ethambutol
embA 4245471 p.Ala747Leu missense_variant 1.0 ethambutol
embA 4245477 p.Met749Leu missense_variant 1.0 ethambutol
embA 4245497 c.2265C>G synonymous_variant 1.0 ethambutol
embA 4245501 p.Ala757Thr missense_variant 1.0 ethambutol
embA 4245506 c.2274C>T synonymous_variant 1.0 ethambutol
embB 4245518 c.-996A>T upstream_gene_variant 1.0 ethambutol
embA 4245524 c.2292G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245530 c.-984T>C upstream_gene_variant 1.0 ethambutol
embA 4245531 p.Ile767Val missense_variant 1.0 ethambutol
embA 4245535 p.Ser768Asn missense_variant 1.0 ethambutol
embB 4245539 c.-975C>G upstream_gene_variant 1.0 ethambutol
embB 4245725 c.-789A>G upstream_gene_variant 1.0 ethambutol
embB 4245726 c.-788T>C upstream_gene_variant 1.0 ethambutol
embB 4245737 c.-777A>C upstream_gene_variant 1.0 ethambutol
embB 4245740 c.-774T>C upstream_gene_variant 1.0 ethambutol
embA 4245785 c.2553G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245845 c.-669T>C upstream_gene_variant 1.0 ethambutol
embB 4245851 c.-663G>C upstream_gene_variant 0.86 ethambutol
embB 4245860 c.-654C>G upstream_gene_variant 0.8 ethambutol
embA 4245885 p.Asp885Thr missense_variant 1.0 ethambutol
embA 4245892 p.Ile887Thr missense_variant 1.0 ethambutol Uncertain significance
embA 4245899 c.2667C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4245902 c.-612G>A upstream_gene_variant 0.7 ethambutol
embB 4245911 c.-603A>G upstream_gene_variant 0.7 ethambutol
embB 4245917 c.-597G>A upstream_gene_variant 0.7 ethambutol
embB 4245980 c.-534C>T upstream_gene_variant 0.8 ethambutol
embA 4245987 p.Gln919Glu missense_variant 0.82 ethambutol
embB 4245992 c.-522C>G upstream_gene_variant 1.0 ethambutol
embB 4246010 c.-504G>C upstream_gene_variant 1.0 ethambutol
embB 4246013 c.-501T>C upstream_gene_variant 1.0 ethambutol
embA 4246020 p.Ala930Thr missense_variant 0.93 ethambutol
embA 4246041 p.Asp937Asn missense_variant 1.0 ethambutol
embB 4246049 c.-465G>C upstream_gene_variant 0.88 ethambutol
embA 4246055 c.2823T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246058 c.-456C>G upstream_gene_variant 0.88 ethambutol
embB 4246064 c.-450T>C upstream_gene_variant 1.0 ethambutol
embB 4246196 c.-318C>G upstream_gene_variant 1.0 ethambutol
embB 4246205 c.-309A>G upstream_gene_variant 1.0 ethambutol
embB 4246211 c.-303T>C upstream_gene_variant 1.0 ethambutol
embB 4246217 c.-297G>A upstream_gene_variant 1.0 ethambutol
embA 4246220 c.2988T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4246223 c.-291C>T upstream_gene_variant 1.0 ethambutol
embA 4246227 p.Ile999Val missense_variant 1.0 ethambutol
embA 4246235 c.3003G>A synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4246242 p.Gln1004Gly missense_variant 1.0 ethambutol
embB 4246250 c.-264G>C upstream_gene_variant 0.64 ethambutol
embB 4246256 c.-258G>T upstream_gene_variant 0.64 ethambutol
embB 4247407 c.894G>C synonymous_variant 1.0 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.96 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.96 ethambutol Not assoc w R - Interim
embB 4247440 c.927C>G synonymous_variant 0.36 ethambutol
embB 4247446 c.933C>T synonymous_variant 0.38 ethambutol
embB 4247452 c.939C>G synonymous_variant 0.62 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.98 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.83 ethambutol
embB 4247506 c.993C>G synonymous_variant 0.84 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247521 c.1008G>A synonymous_variant 0.79 ethambutol Not assoc w R - Interim
embB 4247522 c.1009C>T synonymous_variant 0.79 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.78 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247550 p.Ala346Asp missense_variant 0.83 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>C synonymous_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.92 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.9 ethambutol
embB 4247677 c.1164C>G synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4247684 c.1171T>C synonymous_variant 0.78 ethambutol
embB 4247722 c.1209G>T synonymous_variant 1.0 ethambutol
embB 4247725 c.1212G>C synonymous_variant 1.0 ethambutol
embB 4247729 p.Gly406Pro missense_variant 1.0 ethambutol
embB 4247753 p.Val414Ile missense_variant 0.68 ethambutol Uncertain significance
embB 4247761 c.1248T>C synonymous_variant 1.0 ethambutol
embB 4247773 c.1260G>A synonymous_variant 1.0 ethambutol
embB 4247776 c.1263G>T synonymous_variant 1.0 ethambutol
embB 4247818 c.1305C>G synonymous_variant 0.38 ethambutol
embB 4247819 p.Val436Ile missense_variant 1.0 ethambutol Uncertain significance
embB 4247827 c.1314C>G synonymous_variant 0.35 ethambutol
embB 4247830 c.1317A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247842 c.1329T>C synonymous_variant 0.35 ethambutol
embB 4247851 c.1338C>G synonymous_variant 0.38 ethambutol
embB 4247857 c.1344C>A synonymous_variant 0.38 ethambutol
embB 4247869 c.1356G>A synonymous_variant 0.4 ethambutol Not assoc w R - Interim
embB 4247887 c.1374C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247893 c.1380C>T synonymous_variant 0.67 ethambutol
embB 4247899 p.Met462Ile missense_variant 1.0 ethambutol
embB 4247905 c.1392G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247909 c.1396T>C synonymous_variant 1.0 ethambutol
embB 4247932 c.1419C>G synonymous_variant 1.0 ethambutol
embB 4247940 p.Leu476Trp missense_variant 1.0 ethambutol
embB 4247945 c.1432T>C synonymous_variant 1.0 ethambutol
embB 4247951 p.Ser480Ala missense_variant 1.0 ethambutol
embB 4247956 c.1443G>C synonymous_variant 0.53 ethambutol Not assoc w R - Interim
embB 4247983 c.1470G>C synonymous_variant 0.62 ethambutol
embB 4248007 c.1494C>A synonymous_variant 1.0 ethambutol
embB 4248035 p.Val508Ile missense_variant 1.0 ethambutol
embB 4248041 p.Ala510Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 1.0 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.77 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.77 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 1.0 ethambutol
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248139 c.1626C>G synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248161 c.1648C>T synonymous_variant 0.67 ethambutol Not assoc w R - Interim
embB 4248169 c.1656C>G synonymous_variant 0.67 ethambutol
embB 4248190 c.1677G>C synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embB 4248200 p.Ile563Val missense_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248211 c.1698G>A synonymous_variant 0.79 ethambutol
embB 4248220 c.1707A>C synonymous_variant 1.0 ethambutol
embB 4248241 c.1728C>T synonymous_variant 0.73 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.8 ethambutol
embB 4248298 c.1785C>T synonymous_variant 0.72 ethambutol
embB 4248304 c.1791G>C synonymous_variant 1.0 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.65 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>C synonymous_variant 0.66 ethambutol
embB 4248343 c.1830G>C synonymous_variant 0.4 ethambutol
embB 4248350 c.1837_1839delTTGinsCTC synonymous_variant 1.0 ethambutol
embB 4248355 c.1842A>G synonymous_variant 0.62 ethambutol
embB 4248358 c.1845C>G synonymous_variant 1.0 ethambutol
embB 4248361 c.1848A>C synonymous_variant 1.0 ethambutol
embB 4248368 c.1855C>T synonymous_variant 0.39 ethambutol
embB 4248373 c.1860C>G synonymous_variant 1.0 ethambutol
embB 4248382 c.1869C>G synonymous_variant 1.0 ethambutol
embB 4248386 c.1873C>A synonymous_variant 0.56 ethambutol
embB 4248401 p.Ala630Ser missense_variant 0.4 ethambutol
embB 4248407 p.Leu632Val missense_variant 1.0 ethambutol
embB 4248410 p.Phe633Leu missense_variant 1.0 ethambutol
embB 4248425 c.1912T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248430 c.1917T>C synonymous_variant 0.57 ethambutol
embB 4248432 p.Trp640Phe missense_variant 1.0 ethambutol
embB 4248457 c.1944T>C synonymous_variant 0.62 ethambutol
embB 4249417 c.2904A>G synonymous_variant 0.91 ethambutol
embB 4249423 p.Asp970Glu missense_variant 0.91 ethambutol Uncertain significance
embB 4249424 p.Leu971Met missense_variant 0.91 ethambutol
embB 4249429 c.2916C>T synonymous_variant 0.91 ethambutol
embB 4249432 c.2919A>G synonymous_variant 0.91 ethambutol
embB 4249469 p.Leu986Met missense_variant 1.0 ethambutol
embB 4249486 c.2973T>G synonymous_variant 1.0 ethambutol
embB 4249498 c.2985G>C synonymous_variant 1.0 ethambutol
embB 4249521 p.Ala1003Val missense_variant 1.0 ethambutol
embB 4249525 c.3012T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
aftB 4268081 c.756A>G synonymous_variant 1.0 ethambutol
aftB 4268105 c.732T>C synonymous_variant 1.0 ethambutol
aftB 4268123 p.Ser238Gly missense_variant 1.0 ethambutol
aftB 4268126 c.711G>C synonymous_variant 0.69 ethambutol
aftB 4268129 c.708T>G synonymous_variant 1.0 ethambutol
aftB 4268132 c.705G>C synonymous_variant 0.59 ethambutol
aftB 4268138 c.699A>G synonymous_variant 1.0 ethambutol
aftB 4268144 c.693T>C synonymous_variant 1.0 ethambutol
aftB 4269006 c.-170T>C upstream_gene_variant 1.0 ethambutol
aftB 4269012 c.-176G>C upstream_gene_variant 1.0 ethambutol
aftB 4269033 c.-197T>C upstream_gene_variant 1.0 ethambutol
aftB 4269036 c.-200C>G upstream_gene_variant 0.82 ethambutol
aftB 4269042 c.-206G>C upstream_gene_variant 1.0 ethambutol
aftB 4269201 c.-365A>G upstream_gene_variant 1.0 ethambutol
aftB 4269255 c.-419C>T upstream_gene_variant 0.79 ethambutol
aftB 4269261 c.-425G>A upstream_gene_variant 0.86 ethambutol
aftB 4269264 c.-428C>T upstream_gene_variant 0.86 ethambutol
ubiA 4269314 p.Lys174Gln missense_variant 1.0 ethambutol
ubiA 4269327 p.Lys169Asp missense_variant 0.85 ethambutol
ubiA 4269337 p.Val166Ala missense_variant 0.82 ethambutol
aftB 4269342 c.-506G>T upstream_gene_variant 1.0 ethambutol
ubiA 4269357 p.Ile159Leu missense_variant 1.0 ethambutol
ubiA 4269387 p.Glu149Asp missense_variant 1.0 ethambutol Not assoc w R