TB-Profiler result

Run: ERR323039
Summary

Run ID: ERR323039

Sample name:

Date: 2024-04-14T21:03:49.732268

Number of reads: 752661

Percentage reads mapped: 15.09

Median coverage: 6.0

Strain: La2;lineage4.9

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3.1.2.2 East-African-Indian RD750 0.17
lineage4.9 Euro-American (H37Rv-like) None 0.78
La1.7.1 M.bovis None 0.16
La2 M.caprae None 0.06
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.493_495delATTinsCC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.481_483delGCTinsTG Assoc w R
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.508_510delGTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.514_516delGTCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.532_534delGCAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.799_801delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1147_1149delGCCinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1177_1179delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 0.98 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491290 c.508_510delGTGinsAC frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491296 c.514_516delGTCinsAT frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303462 c.532_534delGCAinsTG frameshift_variant&stop_gained 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.97 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303729 c.799_801delCTAinsTG frameshift_variant&stop_gained 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsCG frameshift_variant&missense_variant 0.92 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
tlyA 1918420 c.481_483delGCTinsTG frameshift_variant&missense_variant 0.73 capreomycin Assoc w R
katG 2155107 p.Ile335Thr missense_variant 0.94 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.9 isoniazid Assoc w R High-level resistance
katG 2155617 c.493_495delATTinsCC frameshift_variant&missense_variant 0.89 isoniazid Assoc w R High-level resistance
fbiB 3642681 c.1147_1149delGCCinsTG frameshift_variant&missense_variant 0.89 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB 3642711 c.1177_1179delCTGinsGA frameshift_variant&missense_variant 0.93 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.94 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 0.94 isoniazid
dnaA 24 c.24C>T synonymous_variant 0.94 isoniazid
dnaA 30 c.30C>G synonymous_variant 0.94 isoniazid
dnaA 33 c.33A>C synonymous_variant 0.94 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.92 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.92 isoniazid
dnaA 714 c.714C>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 717 c.717C>T synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>A synonymous_variant 0.96 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.96 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.96 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.97 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.97 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCT frameshift_variant&synonymous_variant 0.93 isoniazid Uncertain significance
dnaA 819 c.819C>T synonymous_variant 0.96 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.95 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.95 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.96 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.96 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.95 isoniazid
dnaA 891 c.891C>T synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 897 c.897A>G synonymous_variant 0.95 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>G synonymous_variant 0.91 isoniazid
dnaA 912 c.912T>C synonymous_variant 0.91 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.91 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.82 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.84 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.87 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.9 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.88 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 0.9 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.89 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.94 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.93 isoniazid
dnaA 1078 c.1078_1080delCTCinsTG frameshift_variant&missense_variant 0.93 isoniazid Uncertain significance
dnaA 1092 c.1092T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 1095 c.1095C>T synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.85 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.81 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.83 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 0.83 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.87 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.93 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.94 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.95 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 0.98 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 0.98 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.98 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.95 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.97 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.96 isoniazid
dnaA 1311 c.1311C>T synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 1317 c.1317A>G synonymous_variant 0.85 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.91 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.93 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 0.93 isoniazid
dnaA 1437 c.1437G>A synonymous_variant 0.93 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.88 isoniazid
dnaA 1446 c.1446C>G synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 1461 c.1461C>A synonymous_variant 0.88 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 0.88 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 1497 c.1497T>G synonymous_variant 0.91 isoniazid
gyrB 5314 c.75C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5326 c.87T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 5329 c.90C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 5338 c.99C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 5344 c.105C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 5359 c.120C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 5362 c.123T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrB 5396 p.Ala53Ser missense_variant 0.9 levofloxacin
moxifloxacin
gyrB 6106 c.867C>A synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6122 p.Ala295Ser missense_variant 0.6 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6166 c.927C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6172 c.933C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6316 c.-986G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.98 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6397 c.1158G>A synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6415 c.-887G>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>T upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 0.88 levofloxacin Uncertain significance
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.92 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6911 p.Asn558His missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6997 c.-305G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>G upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 7076 c.1837_1839delCTAinsTG frameshift_variant&stop_gained 0.94 levofloxacin Uncertain significance
moxifloxacin
gyrA 7081 c.-221T>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7174 c.-128C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 7307 c.6A>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7322 c.21G>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7325 c.24delTinsAGGC conservative_inframe_insertion&synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7362 c.61_63delGAGinsCA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7643 c.342C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7646 c.345C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7697 c.396C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7742 c.441G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 0.97 levofloxacin
moxifloxacin
gyrA 7820 c.519G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7884 c.583_585delCGTinsGC frameshift_variant&missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 7901 c.600G>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7904 c.603G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8585 c.1284C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8983 p.Cys561Ser missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.91 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.82 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9323 c.2022C>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9326 c.2025G>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9383 c.2082T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9435 c.2134C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9602 c.2301T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9638 c.2337C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
Rv0010c 13894 c.-336C>T upstream_gene_variant 0.92 isoniazid
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.94 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.95 isoniazid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490983 c.201G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490988 p.Leu69Gln missense_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491040 c.258C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491136 c.354C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>T synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491175 c.393G>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491178 c.396G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491320 p.Ala180Gln missense_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491686 p.Thr302Gln missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fgd1 491704 c.922C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491712 c.930T>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fgd1 491721 c.939A>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
mshA 574607 c.-741G>A upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574616 c.-732G>C upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 574640 c.-708G>A upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574646 c.-702G>A upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.93 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.88 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.85 ethionamide
isoniazid
mshA 575000 c.-348C>G upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 575009 c.-339T>C upstream_gene_variant 0.82 ethionamide
isoniazid
mshA 575011 c.-337G>A upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 575022 c.-326C>T upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 575034 c.-314_-312delTTAinsCG upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 575042 c.-306T>C upstream_gene_variant 0.91 ethionamide
isoniazid
mshA 575051 c.-297A>G upstream_gene_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 575072 c.-276G>C upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 0.94 ethionamide
isoniazid Uncertain significance
mshA 575081 c.-267A>G upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575087 c.-261C>G upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575109 c.-239G>T upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575114 c.-234G>A upstream_gene_variant 0.94 ethionamide
isoniazid Uncertain significance
mshA 575117 c.-231T>C upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 575118 c.-230A>G upstream_gene_variant 0.93 ethionamide
isoniazid Uncertain significance
mshA 575123 c.-225A>G upstream_gene_variant 0.9 ethionamide
isoniazid
mshA 575124 c.-224_-222delGGGinsCT upstream_gene_variant 0.9 ethionamide
isoniazid
mshA 575144 c.-204T>G upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 575153 c.-195C>A upstream_gene_variant 0.88 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575161 c.-187_-186delTTinsCC upstream_gene_variant 0.8 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 0.79 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.86 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.9 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.95 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.97 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.97 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.93 ethionamide
isoniazid
mshA 575779 p.Glu144Asp missense_variant 0.93 ethionamide
isoniazid
mshA 575780 c.433_435delCCGinsGC frameshift_variant&missense_variant 0.9 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575821 c.474G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.92 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.89 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.89 ethionamide
isoniazid
mshA 575851 c.504C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575887 c.540G>T synonymous_variant 0.89 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 0.89 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575899 c.552G>A synonymous_variant 0.94 ethionamide
isoniazid
mshA 575916 p.Asp190Val missense_variant 0.9 ethionamide
isoniazid
ccsA 619588 c.-303C>G upstream_gene_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619594 c.-297G>A upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619624 c.-267C>T upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-255delTCCinsGTG upstream_gene_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 619655 c.-236A>G upstream_gene_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>C upstream_gene_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619684 c.-207G>A upstream_gene_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 619912 p.Val8Ile missense_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 619923 c.33C>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 619935 c.45C>T synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 619953 c.63C>G synonymous_variant 0.87 capreomycin
amikacin
kanamycin
ccsA 619984 c.94C>T synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620197 p.Gln103Met missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620238 c.348G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620284 c.394_396delGCGinsCA frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620291 p.Tyr134Phe missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620325 c.435G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>T synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.92 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620400 c.510C>T synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620430 c.540C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620442 c.552G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620448 c.558C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620589 c.699G>T synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.86 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.88 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.89 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 0.91 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620685 c.795G>A synonymous_variant 0.97 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620698 p.Val270Ile missense_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>A synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.97 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620781 c.891C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 0.98 capreomycin
amikacin
kanamycin
ccsA 620829 c.939G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 657183 c.288G>A synonymous_variant 0.83 ethionamide
Rv0565c 657189 c.282C>A synonymous_variant 0.83 ethionamide
Rv0565c 657193 p.Met93Thr missense_variant 0.83 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.89 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 0.91 ethionamide Uncertain significance
Rv0565c 657210 c.261C>T synonymous_variant 0.92 ethionamide Not assoc w R - Interim
Rv0565c 657213 c.258C>T synonymous_variant 0.92 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.92 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.97 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.87 ethionamide Uncertain significance
Rv0565c 657252 c.219G>C synonymous_variant 0.95 ethionamide
Rv0565c 657255 c.216G>A synonymous_variant 0.95 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.97 ethionamide
Rv0565c 657294 c.177C>A synonymous_variant 0.95 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.94 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 0.94 ethionamide
Rv0565c 657312 c.159C>T synonymous_variant 0.94 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.93 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.92 ethionamide
Rv0565c 657330 c.141C>T synonymous_variant 0.87 ethionamide
Rv0565c 657337 p.Arg45Gln missense_variant 0.88 ethionamide Uncertain significance
Rv0565c 657340 p.Ala44Glu missense_variant 0.86 ethionamide
Rv0565c 657342 c.129T>C synonymous_variant 0.86 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.86 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.86 ethionamide
Rv0565c 657359 p.Thr38Ala missense_variant 0.82 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.87 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.94 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 0.94 ethionamide
Rv0565c 657668 c.-198C>T upstream_gene_variant 0.94 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.94 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.94 ethionamide
Rv0565c 657695 c.-225C>G upstream_gene_variant 0.95 ethionamide
Rv0565c 657704 c.-234G>A upstream_gene_variant 0.96 ethionamide
Rv0565c 657725 c.-255G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 0.92 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.91 ethionamide
hadA 731686 c.-244_-243insATGT upstream_gene_variant 0.93 isoniazid
hadA 731689 c.-240_-237delAGAC upstream_gene_variant 0.93 isoniazid
hadA 731695 c.-235C>T upstream_gene_variant 0.93 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 0.94 isoniazid
hadA 731708 c.-222G>A upstream_gene_variant 0.95 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.95 isoniazid
hadA 731726 c.-204C>G upstream_gene_variant 0.98 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.98 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 1.0 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.98 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.95 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.97 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.94 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.91 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.97 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.96 isoniazid
hadA 732280 c.351C>G synonymous_variant 0.83 isoniazid
hadA 732305 c.376_378delATCinsGG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.89 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.84 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.95 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.96 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.94 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.97 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.98 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.96 isoniazid
nusG 734093 c.-161A>G upstream_gene_variant 0.9 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.92 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.92 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.92 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.85 rifampicin
nusG 734153 c.-101C>A upstream_gene_variant 0.7 rifampicin
nusG 734364 c.111G>C synonymous_variant 0.7 rifampicin
nusG 734367 c.114C>G synonymous_variant 0.7 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.73 rifampicin
nusG 734373 c.120G>C synonymous_variant 0.79 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.95 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.95 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.93 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.94 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.95 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.94 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.94 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.94 rifampicin
nusG 734520 c.267C>A synonymous_variant 0.95 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.91 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.93 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 0.9 rifampicin
nusG 734814 c.561G>C synonymous_variant 0.93 rifampicin
nusG 734820 c.567A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 0.95 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>T synonymous_variant 0.97 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.97 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.97 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.95 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.98 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.94 rifampicin
nusG 734931 c.678A>T synonymous_variant 0.96 rifampicin
nusG 734940 c.687G>A synonymous_variant 0.95 rifampicin
nusG 734943 c.690G>C synonymous_variant 0.89 rifampicin
nusG 734950 p.Gly233Thr missense_variant 0.94 rifampicin
rpoB 759944 c.138A>G synonymous_variant 0.8 rifampicin
rpoB 759947 c.141C>T synonymous_variant 0.8 rifampicin
rpoB 759950 c.144T>C synonymous_variant 0.8 rifampicin
rpoB 759956 c.150C>G synonymous_variant 0.8 rifampicin
rpoB 759965 c.159T>C synonymous_variant 0.8 rifampicin
rpoB 759968 c.162G>C synonymous_variant 0.8 rifampicin
rpoB 759971 c.165C>T synonymous_variant 0.8 rifampicin
rpoB 759978 c.172C>T synonymous_variant 0.8 rifampicin
rpoB 759986 c.180T>C synonymous_variant 0.8 rifampicin
rpoB 760056 c.250_252delCTCinsTG frameshift_variant&missense_variant 0.92 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.95 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760109 c.303C>T synonymous_variant 0.95 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.95 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.98 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.98 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.98 rifampicin
rpoB 760181 c.375T>A synonymous_variant 0.98 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760271 c.465C>G synonymous_variant 0.98 rifampicin
rpoB 760274 c.468G>A synonymous_variant 0.98 rifampicin
rpoB 760295 c.489C>T synonymous_variant 0.98 rifampicin
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.98 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.98 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.97 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760358 c.552C>G synonymous_variant 0.98 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.98 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.97 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.97 rifampicin
rpoB 760391 c.585C>T synonymous_variant 0.95 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>T synonymous_variant 0.95 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.94 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.94 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>G synonymous_variant 0.97 rifampicin
rpoB 760520 c.714C>G synonymous_variant 0.96 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760526 c.720G>A synonymous_variant 0.96 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.96 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760601 c.795C>T synonymous_variant 0.96 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760622 c.816C>T synonymous_variant 0.97 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.97 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.99 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.97 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.96 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.96 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.97 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.98 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.98 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsCG frameshift_variant&missense_variant 0.98 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 0.98 rifampicin
rpoB 760916 c.1110C>G synonymous_variant 0.98 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.97 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760937 c.1131G>A synonymous_variant 0.98 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.98 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.98 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 0.98 rifampicin
rpoB 760991 c.1185G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.98 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.98 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.97 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.97 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.97 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 0.94 rifampicin
rpoB 761192 c.1386C>G synonymous_variant 0.94 rifampicin
rpoB 761195 c.1389G>T synonymous_variant 0.94 rifampicin
rpoB 761198 c.1392G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 0.96 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 0.96 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.98 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 0.99 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.97 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.97 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.97 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.97 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.96 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.96 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.96 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.98 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.98 rifampicin
rpoB 761465 c.1659G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761471 c.1665C>T synonymous_variant 0.98 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 0.98 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.98 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.98 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.99 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.99 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>A synonymous_variant 0.99 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 0.98 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.99 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.96 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.92 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.94 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.95 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.95 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.95 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.97 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.97 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 0.96 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.97 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.98 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.98 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.97 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.97 rifampicin
rpoB 761913 c.2107_2109delGACinsCA frameshift_variant&missense_variant 0.97 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.97 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.98 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>T synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.99 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 0.99 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.98 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762431 c.2625C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.97 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.97 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.98 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762563 c.-807G>A upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.93 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.91 rifampicin
rpoC 762776 c.-594C>G upstream_gene_variant 1.0 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762795 p.Asp997Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 762902 c.-468C>T upstream_gene_variant 0.96 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 0.96 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 0.99 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 0.96 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 0.92 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.97 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.96 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.96 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.96 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.98 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763241 c.-129G>A upstream_gene_variant 0.97 rifampicin
rpoC 763250 c.-120C>T upstream_gene_variant 0.97 rifampicin
rpoC 763253 c.-117G>T upstream_gene_variant 0.96 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.9 rifampicin
rpoC 763265 c.-105G>A upstream_gene_variant 0.89 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.89 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.99 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.99 rifampicin
rpoC 763633 c.264T>A synonymous_variant 0.99 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.99 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.98 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.98 rifampicin
rpoC 763714 c.345G>T synonymous_variant 0.98 rifampicin
rpoC 763726 c.357C>T synonymous_variant 0.99 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.99 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.97 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.99 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763771 c.402C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763780 c.411C>G synonymous_variant 0.98 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.97 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.98 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 0.95 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 0.95 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.94 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.94 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.96 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.98 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.98 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.98 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.98 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.98 rifampicin
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.98 rifampicin
rpoC 763963 c.594C>G synonymous_variant 0.98 rifampicin
rpoC 763967 p.Gly200Ser missense_variant 0.96 rifampicin
rpoC 763972 c.603C>T synonymous_variant 0.96 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.96 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.98 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.98 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.98 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.98 rifampicin
rpoC 764044 c.675T>G synonymous_variant 0.98 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.98 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764159 c.790C>T synonymous_variant 1.0 rifampicin
rpoC 764167 c.798G>A synonymous_variant 0.98 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 0.98 rifampicin
rpoC 764218 c.849C>T synonymous_variant 0.98 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>A synonymous_variant 0.98 rifampicin
rpoC 764246 c.877_879delCTCinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.96 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.96 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.94 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.94 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.94 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.94 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.95 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.94 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.94 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.97 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.97 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.98 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.98 rifampicin
rpoC 764605 c.1236G>A synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 0.94 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 1.0 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 0.98 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.98 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.98 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765208 c.1839T>C synonymous_variant 0.92 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 0.94 rifampicin
rpoC 765233 c.1864_1866delGCCinsTG frameshift_variant&missense_variant 0.94 rifampicin
rpoC 765247 c.1878C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765248 c.1879T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765251 c.1882_1884delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765283 c.1914C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765292 c.1923G>T synonymous_variant 0.97 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765391 c.2022C>T synonymous_variant 1.0 rifampicin
rpoC 765406 c.2037G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.98 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.98 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.97 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.99 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.99 rifampicin
rpoC 765625 c.2256C>T synonymous_variant 0.98 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 0.98 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 0.98 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.98 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.98 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.98 rifampicin
rpoC 765811 c.2442T>A synonymous_variant 0.97 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.96 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.96 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.97 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.98 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.96 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.95 rifampicin
rpoC 766093 c.2724C>A synonymous_variant 0.97 rifampicin
rpoC 766095 p.Thr909Ser missense_variant 0.97 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.97 rifampicin
rpoC 766123 c.2754C>A synonymous_variant 0.96 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.96 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.92 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766270 c.2901G>C synonymous_variant 0.88 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.93 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.93 rifampicin
rpoC 766280 c.2911_2913delAGCinsGT frameshift_variant&missense_variant 0.93 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.96 rifampicin
rpoC 766309 c.2940G>A synonymous_variant 0.94 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.95 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.95 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 0.99 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.99 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.99 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.99 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.99 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.99 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.99 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.98 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.97 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.99 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.97 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 0.97 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.99 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.97 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.97 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.99 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 0.99 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.99 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.99 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.99 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.98 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 0.97 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.95 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.98 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.98 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.96 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.96 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 0.95 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>G synonymous_variant 0.95 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.96 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.96 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.98 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.98 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.97 rifampicin
rpoC 767149 c.3780C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>A synonymous_variant 0.97 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.97 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>G synonymous_variant 0.97 rifampicin
rpoC 767264 p.Ala1299Gln missense_variant 0.96 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.92 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.84 rifampicin
mmpL5 775909 p.Leu858Phe missense_variant 0.79 clofazimine
bedaquiline
mmpL5 775910 c.2571G>A synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775940 c.2541C>T synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.87 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.69 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.86 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.52 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776008 p.His825Tyr missense_variant 0.36 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.89 clofazimine
bedaquiline
mmpL5 776015 c.2464_2466delATCinsCA frameshift_variant&missense_variant 0.36 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776024 c.2457G>C synonymous_variant 0.4 clofazimine
bedaquiline
mmpL5 776027 c.2454G>C synonymous_variant 0.4 clofazimine
bedaquiline
mmpL5 776030 c.2451G>T synonymous_variant 0.79 clofazimine
bedaquiline
mmpL5 776036 c.2445G>C synonymous_variant 0.77 clofazimine
bedaquiline
mmpL5 776039 c.2442C>G synonymous_variant 0.43 clofazimine
bedaquiline
mmpL5 776056 p.Val809Leu missense_variant 0.85 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 0.91 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>T synonymous_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>T synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>G synonymous_variant 1.0 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.98 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.98 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.98 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>G synonymous_variant 0.98 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.98 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.95 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.95 streptomycin
rpsL 781883 c.324G>A synonymous_variant 0.93 streptomycin
rpsL 781886 c.327C>T synonymous_variant 0.95 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.95 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.96 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.96 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.96 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.94 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 0.98 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.99 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.99 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.99 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.97 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.98 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.98 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 0.94 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.95 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.97 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.97 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.98 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.98 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.98 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.97 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 0.97 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.98 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.98 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 0.95 linezolid
rplC 800806 c.-3G>T upstream_gene_variant 0.9 linezolid
rplC 800807 c.-2_-1insT upstream_gene_variant 0.9 linezolid
rplC 800814 c.6A>G synonymous_variant 0.95 linezolid
rplC 800815 c.7C>A synonymous_variant 0.91 linezolid
rplC 800820 c.12G>A synonymous_variant 0.95 linezolid
rplC 800829 c.21C>G synonymous_variant 0.96 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 0.96 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.95 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800901 c.93C>G synonymous_variant 0.92 linezolid
rplC 800910 c.102C>T synonymous_variant 0.95 linezolid
rplC 800913 c.105G>A synonymous_variant 0.95 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800919 c.111C>G synonymous_variant 0.95 linezolid
rplC 800931 c.123G>C synonymous_variant 0.93 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801231 c.423C>T synonymous_variant 0.95 linezolid
rplC 801246 c.438C>T synonymous_variant 0.96 linezolid
rplC 801255 c.447C>A synonymous_variant 0.96 linezolid
rplC 801267 c.459A>C synonymous_variant 0.94 linezolid
rplC 801270 c.462T>C synonymous_variant 0.95 linezolid
rplC 801273 c.465C>G synonymous_variant 0.95 linezolid
rplC 801279 c.471G>C synonymous_variant 0.96 linezolid
rplC 801285 c.477G>A synonymous_variant 0.97 linezolid
rplC 801309 c.501C>G synonymous_variant 0.97 linezolid
rplC 801312 c.504G>C synonymous_variant 0.97 linezolid
rplC 801324 c.516T>C synonymous_variant 0.97 linezolid
rplC 801330 c.522G>T synonymous_variant 1.0 linezolid
rplC 801333 c.525G>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 1.0 linezolid
rplC 801341 p.Leu178Gln missense_variant 1.0 linezolid
rplC 801348 c.540T>G synonymous_variant 1.0 linezolid
rplC 801349 p.Leu181Val missense_variant 1.0 linezolid
rplC 801357 c.549T>C synonymous_variant 1.0 linezolid
rplC 801372 c.564G>A synonymous_variant 1.0 linezolid
rplC 801385 c.577C>T synonymous_variant 1.0 linezolid
rplC 801402 c.594T>C synonymous_variant 0.95 linezolid
rplC 801405 c.597T>C synonymous_variant 0.95 linezolid
rplC 801408 c.600C>A synonymous_variant 0.95 linezolid
rplC 801423 c.615G>C synonymous_variant 0.95 linezolid
rplC 801426 c.618C>T synonymous_variant 0.95 linezolid
rplC 801427 p.Met207Val missense_variant 0.95 linezolid
rplC 801437 p.Ser210Thr missense_variant 0.95 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 0.82 linezolid
fbiC 1303441 c.511T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303449 c.519C>T synonymous_variant 0.88 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303470 c.540T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303538 p.Arg203Leu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303596 c.666G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 0.98 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303629 c.699C>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303755 c.825T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303782 c.852C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304172 c.1242G>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304178 c.1248G>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304184 c.1254G>T synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304190 c.1260G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304196 c.1266C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304205 c.1275C>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304220 c.1290G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304222 p.Val431Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304226 c.1296C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304227 p.Met433Leu missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304252 p.Val441Ala missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304502 c.1572G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304532 c.1602G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304541 c.1611C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304778 c.1848T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304797 p.Ala623Asn missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304871 c.1941G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1943delAGinsTC synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304982 c.2052G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305039 c.2109G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305354 c.2424C>T synonymous_variant 0.87 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305357 c.2427C>G synonymous_variant 0.88 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305361 c.2431C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1305414 c.2484G>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305426 c.2496G>A synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305427 c.2497C>T synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305435 c.2505G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305446 p.Gly839Ala missense_variant 0.83 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
sigE 1364634 c.222C>G synonymous_variant 0.92 pyrazinamide
sigE 1364640 c.228G>C synonymous_variant 0.92 pyrazinamide
sigE 1364647 c.235_237delGCCinsAG frameshift_variant&missense_variant 0.92 pyrazinamide Uncertain significance
sigE 1364652 c.240C>G synonymous_variant 0.92 pyrazinamide
sigE 1364667 c.255T>C synonymous_variant 0.92 pyrazinamide
sigE 1364671 c.259C>T synonymous_variant 0.92 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.92 pyrazinamide
sigE 1364677 c.265_267delCGTinsAA frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364691 c.279T>C synonymous_variant 0.93 pyrazinamide
sigE 1364694 c.282G>C synonymous_variant 0.94 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 0.95 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.94 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.94 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 0.94 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.94 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.94 pyrazinamide
sigE 1364745 c.333C>T synonymous_variant 0.94 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364751 c.339C>G synonymous_variant 0.95 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.95 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.95 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.96 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.97 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.96 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.96 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.95 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.95 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.95 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.95 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.91 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 0.88 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 0.86 pyrazinamide
sigE 1364874 c.462C>T synonymous_variant 0.86 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.92 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
sigE 1364892 c.480C>G synonymous_variant 0.85 pyrazinamide
sigE 1364910 c.498G>A synonymous_variant 0.83 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.83 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.86 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.85 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 0.86 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.92 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 0.83 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.88 pyrazinamide
sigE 1364964 c.552T>G synonymous_variant 0.88 pyrazinamide
sigE 1364967 c.555C>T synonymous_variant 0.88 pyrazinamide
sigE 1364973 c.561G>A synonymous_variant 0.88 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 0.93 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.93 pyrazinamide
sigE 1364988 c.576G>A synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
sigE 1365003 c.591T>C synonymous_variant 0.93 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.93 pyrazinamide
sigE 1365019 c.607C>T synonymous_variant 0.82 pyrazinamide
embR 1416280 c.1068A>G synonymous_variant 0.86 ethambutol
embR 1416285 p.Glu355Gln missense_variant 0.86 ethambutol
embR 1416289 c.1059G>A synonymous_variant 0.81 ethambutol
embR 1416301 c.1047C>A synonymous_variant 0.83 ethambutol
embR 1416310 c.1038G>C synonymous_variant 0.89 ethambutol
embR 1416313 c.1035A>G synonymous_variant 0.84 ethambutol
embR 1416316 c.1032C>G synonymous_variant 0.84 ethambutol
embR 1416330 p.Val340Ile missense_variant 0.9 ethambutol
embR 1416332 p.Tyr339Phe missense_variant 0.9 ethambutol
embR 1416335 p.Asn338Ser missense_variant 0.9 ethambutol
embR 1416343 c.1005G>C synonymous_variant 0.9 ethambutol
embR 1416364 c.984C>T synonymous_variant 0.86 ethambutol
atpE 1460807 c.-238C>T upstream_gene_variant 0.94 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 0.94 bedaquiline
atpE 1460828 c.-217C>T upstream_gene_variant 0.94 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.95 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 0.95 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 0.93 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 0.93 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 0.96 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 0.94 bedaquiline
atpE 1460895 c.-150_-148delGCAinsTC upstream_gene_variant 0.94 bedaquiline
atpE 1460900 c.-145T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460904 c.-141C>T upstream_gene_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 0.45 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.46 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472223 n.378C>G non_coding_transcript_exon_variant 0.48 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472228 n.383G>C non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.49 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.51 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.51 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.47 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472256 n.411T>A non_coding_transcript_exon_variant 0.48 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.52 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 0.65 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>G non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.99 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 0.91 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 0.88 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.88 capreomycin
linezolid
rrl 1473433 n.-225T>C upstream_gene_variant 0.87 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.88 capreomycin
linezolid
rrl 1473449 n.-209G>A upstream_gene_variant 0.89 capreomycin
linezolid
rrl 1473454 n.-204A>G upstream_gene_variant 0.88 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473918 n.261C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473943 n.286G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473994 n.337C>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474011 n.354G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474018 n.361G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474030 n.373G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474110 n.453A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474409 n.756_774delACCCACACGCGCATACGCG non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474433 n.776G>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474435 n.779_783delTGAAT non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474945 n.1288C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474995 n.1338T>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475007 n.1350C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475018 n.1361G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475404 n.1747A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.86 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.28 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.35 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.37 capreomycin
linezolid
rrl 1476384 n.2727G>A non_coding_transcript_exon_variant 0.36 capreomycin
linezolid
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.46 capreomycin
linezolid
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.73 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
inhA 1673475 c.-727A>C upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673499 c.-703T>C upstream_gene_variant 0.84 ethionamide
isoniazid Uncertain significance
inhA 1673505 c.-697A>T upstream_gene_variant 0.84 ethionamide
isoniazid
inhA 1673517 c.-685G>C upstream_gene_variant 0.86 ethionamide
isoniazid
inhA 1673524 c.-678C>T upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673547 c.-655T>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673565 c.-637G>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.92 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>T upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673592 c.-610G>A upstream_gene_variant 0.92 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.92 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673615 p.Glu59Val missense_variant 0.94 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.81 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.73 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673697 c.-505G>C upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.84 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.84 ethionamide
isoniazid
inhA 1673724 c.-478A>C upstream_gene_variant 0.89 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673730 c.-472C>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.94 ethionamide
isoniazid
inhA 1673745 c.-457G>A upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.94 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.94 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.94 ethionamide
isoniazid
inhA 1673784 c.-418G>C upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 0.93 ethionamide
isoniazid
fabG1 1673830 p.Lys131Arg missense_variant 0.93 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 0.87 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 0.87 ethionamide
isoniazid
fabG1 1673844 p.Met135Ile missense_variant 0.87 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 0.88 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673856 c.-346T>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673865 c.-337C>A upstream_gene_variant 0.96 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 0.96 ethionamide
isoniazid
inhA 1673877 c.-325C>T upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673901 c.-301A>C upstream_gene_variant 0.89 ethionamide
isoniazid
inhA 1673904 c.-298C>G upstream_gene_variant 0.89 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.89 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.85 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1673925 c.-277C>G upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.92 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674507 c.306G>A synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674537 c.336C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674588 c.387G>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674619 p.Pro140Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674687 c.486G>A synonymous_variant 0.96 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674690 c.489C>G synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674696 c.495G>A synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674729 c.528G>A synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674745 p.Tyr182Ala missense_variant 0.95 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.96 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674777 c.576C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674820 c.619_621delCTCinsTG frameshift_variant&missense_variant 0.94 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.96 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.97 ethionamide
isoniazid