TB-Profiler result

Run: ERR323053
Summary

Run ID: ERR323053

Sample name:

Date: 2024-04-14T23:38:09.315316

Number of reads: 678857

Percentage reads mapped: 16.83

Median coverage: 5.0

Strain: La2;lineage4.9;lineage9

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.3.2 Euro-American (LAM) None 0.06
lineage9 Lineage 9 None 0.07
lineage3.1.2.2 East-African-Indian RD750 0.16
lineage4.9 Euro-American (H37Rv-like) None 0.76
La1.7.1 M.bovis None 0.14
La2 M.caprae None 0.07
lineage4.3.4.2 Euro-American (LAM) RD174 0.08
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
c.493_495delATTinsCC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.508_510delGTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.514_516delGTCinsAT Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.532_534delGCAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.799_801delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1779delC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1785_1786insC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1825_1827delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1177_1179delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 0.96 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491290 c.508_510delGTGinsAC frameshift_variant&missense_variant 0.83 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491296 c.514_516delGTCinsAT frameshift_variant&missense_variant 0.85 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.95 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303462 c.532_534delGCAinsTG frameshift_variant&stop_gained 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.86 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303729 c.799_801delCTAinsTG frameshift_variant&stop_gained 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsCG frameshift_variant&missense_variant 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304708 c.1779delC frameshift_variant 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304715 c.1785_1786insC frameshift_variant 0.82 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304755 c.1825_1827delCTAinsTG frameshift_variant&stop_gained 0.95 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.73 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155107 p.Ile335Thr missense_variant 0.93 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.81 isoniazid Assoc w R High-level resistance
katG 2155617 c.493_495delATTinsCC frameshift_variant&missense_variant 0.92 isoniazid Assoc w R High-level resistance
fbiB 3642711 c.1177_1179delCTGinsGA frameshift_variant&missense_variant 0.91 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.8 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 0.83 isoniazid
dnaA 24 c.24C>T synonymous_variant 0.83 isoniazid
dnaA 30 c.30C>G synonymous_variant 0.78 isoniazid
dnaA 33 c.33A>C synonymous_variant 0.78 isoniazid
dnaA 692 c.694delA frameshift_variant 0.79 isoniazid Uncertain significance
dnaA 705 c.705A>G synonymous_variant 0.84 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.85 isoniazid
dnaA 714 c.714C>G synonymous_variant 0.9 isoniazid Not assoc w R - Interim
dnaA 717 c.717C>T synonymous_variant 0.9 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>A synonymous_variant 0.94 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.94 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.92 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.95 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.97 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCT frameshift_variant&synonymous_variant 0.97 isoniazid Uncertain significance
dnaA 819 c.819C>T synonymous_variant 0.96 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.96 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.96 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.96 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.96 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.96 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.96 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.88 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.86 isoniazid
dnaA 891 c.891C>T synonymous_variant 0.84 isoniazid Not assoc w R - Interim
dnaA 897 c.897A>G synonymous_variant 0.81 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>G synonymous_variant 0.69 isoniazid
dnaA 912 c.912T>C synonymous_variant 0.67 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.67 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.67 isoniazid Not assoc w R - Interim
dnaA 936 c.936C>G synonymous_variant 0.69 isoniazid
dnaA 939 c.939C>G synonymous_variant 0.69 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.67 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.67 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.95 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.95 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.97 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.92 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.92 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.92 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 0.93 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.93 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.91 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.88 isoniazid
dnaA 1078 c.1078_1080delCTCinsTG frameshift_variant&missense_variant 0.87 isoniazid Uncertain significance
dnaA 1092 c.1092T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 1095 c.1095C>T synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.74 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.71 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.74 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 0.74 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.76 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.85 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.88 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 0.94 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 0.94 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.94 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.9 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.92 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.94 isoniazid
dnaA 1311 c.1311C>T synonymous_variant 0.95 isoniazid Not assoc w R - Interim
dnaA 1317 c.1317A>G synonymous_variant 0.93 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.91 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.83 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.84 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 0.89 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 0.89 isoniazid
dnaA 1437 c.1437G>A synonymous_variant 0.89 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 0.86 isoniazid
dnaA 1446 c.1446C>G synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 1461 c.1461C>A synonymous_variant 0.86 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 1497 c.1497T>G synonymous_variant 0.8 isoniazid
dnaA 1500 c.1500C>G synonymous_variant 0.79 isoniazid
dnaA 1503 c.1503C>T synonymous_variant 0.83 isoniazid
dnaA 1506 c.1506T>A synonymous_variant 0.91 isoniazid
gyrB 5314 c.75C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5326 c.87T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 5338 c.99C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5341 c.102T>A synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5344 c.105C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 5359 c.120C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 5362 c.123T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 0.92 levofloxacin Uncertain significance
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrB 5396 p.Ala53Ser missense_variant 0.87 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrB 6106 c.867C>A synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.86 levofloxacin
moxifloxacin
gyrB 6127 c.888G>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrB 6166 c.927C>T synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6172 c.933C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.85 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>A synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6316 c.-986G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 0.96 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrB 6391 c.1152G>C synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6397 c.1158G>A synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6673 c.-629A>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.92 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.88 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6808 c.1569C>T synonymous_variant 0.88 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.88 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrB 6824 c.1585C>T synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6898 c.-404G>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6902 c.1663_1665delCTCinsTG frameshift_variant&missense_variant 0.82 levofloxacin Uncertain significance
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.85 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6997 c.-305G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.97 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 7076 c.1837_1839delCTAinsTG frameshift_variant&stop_gained 0.96 levofloxacin Uncertain significance
moxifloxacin
gyrA 7081 c.-221T>G upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7174 c.-128C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7362 c.61_63delGAGinsCA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7550 c.249C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7643 c.342C>T synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7646 c.345C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 7742 c.441G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 0.97 levofloxacin
moxifloxacin
gyrA 7820 c.519G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7884 c.583_585delCGTinsGC frameshift_variant&missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 7901 c.600G>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7904 c.603G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.88 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.89 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.91 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8765 p.Asp488Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8789 c.1488C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8792 c.1491G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8798 c.1497C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8810 c.1509A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8818 p.Ser506Asn missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8829 c.1528T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8840 c.1539C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8873 c.1572A>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8888 c.1587C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8933 c.1632G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8936 c.1635G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.97 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>A synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9197 c.1896G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9326 c.2025G>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 9383 c.2082T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Glu missense_variant 0.83 levofloxacin
moxifloxacin
gyrA 9435 c.2134C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
Rv0010c 13903 c.-345A>G upstream_gene_variant 0.76 isoniazid
Rv0010c 13909 c.-351G>C upstream_gene_variant 0.76 isoniazid
fgd1 490887 c.105G>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 490899 c.117C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 490983 c.201G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490988 p.Leu69Gln missense_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 491040 c.258C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491136 c.354C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491175 c.393G>A synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491178 c.396G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Leu missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491223 c.441C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491283 p.Asp167Glu missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491286 c.504G>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491307 c.525C>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 491310 c.528C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491320 p.Ala180Gln missense_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491325 c.543G>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491340 c.558C>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491643 c.861G>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491658 c.876A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fgd1 491673 c.891A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491676 c.894T>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491679 c.897A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491686 p.Thr302Gln missense_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491697 c.915G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491704 c.922C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491709 c.927A>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fgd1 491712 c.930T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
mshA 574607 c.-741G>A upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 574616 c.-732G>C upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 574640 c.-708G>A upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.92 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.92 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 575000 c.-348C>G upstream_gene_variant 0.86 ethionamide
isoniazid
mshA 575009 c.-339T>C upstream_gene_variant 0.88 ethionamide
isoniazid
mshA 575011 c.-337G>A upstream_gene_variant 0.89 ethionamide
isoniazid
mshA 575022 c.-326C>T upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 575034 c.-314_-312delTTAinsCG upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 575042 c.-306T>C upstream_gene_variant 0.96 ethionamide
isoniazid
mshA 575051 c.-297A>G upstream_gene_variant 0.96 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 0.93 ethionamide
isoniazid
mshA 575072 c.-276G>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 0.97 ethionamide
isoniazid Uncertain significance
mshA 575081 c.-267A>G upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 575087 c.-261C>G upstream_gene_variant 0.98 ethionamide
isoniazid
mshA 575109 c.-239G>T upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575114 c.-234G>A upstream_gene_variant 0.97 ethionamide
isoniazid Uncertain significance
mshA 575117 c.-231T>C upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575118 c.-230A>G upstream_gene_variant 0.97 ethionamide
isoniazid Uncertain significance
mshA 575123 c.-225A>G upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575124 c.-224_-222delGGGinsCT upstream_gene_variant 0.97 ethionamide
isoniazid
mshA 575144 c.-204T>G upstream_gene_variant 0.94 ethionamide
isoniazid
mshA 575153 c.-195C>A upstream_gene_variant 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575161 c.-187_-186delTTinsCC upstream_gene_variant 0.95 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.82 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575695 c.348C>G synonymous_variant 0.92 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.95 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.96 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.96 ethionamide
isoniazid
mshA 575779 p.Glu144Asp missense_variant 0.96 ethionamide
isoniazid
mshA 575780 c.433_435delCCGinsGC frameshift_variant&missense_variant 0.96 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575821 c.474G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.93 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.92 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.9 ethionamide
isoniazid
mshA 575851 c.504C>G synonymous_variant 0.9 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.91 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.87 ethionamide
isoniazid
mshA 575887 c.540G>T synonymous_variant 0.85 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 0.85 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.85 ethionamide
isoniazid
mshA 575899 c.552G>A synonymous_variant 0.86 ethionamide
isoniazid
mshA 575916 p.Asp190Val missense_variant 0.9 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619588 c.-303C>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619594 c.-297G>A upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619624 c.-267C>T upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619634 c.-257_-255delTCCinsGTG upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619654 c.-237A>G upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619669 c.-222G>C upstream_gene_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 619672 c.-219A>C upstream_gene_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 619684 c.-207G>A upstream_gene_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 619909 p.Asn7Asp missense_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 619912 p.Val8Ile missense_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 619923 c.33C>G synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 619935 c.45C>T synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 619953 c.63C>G synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 619984 c.94C>T synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620238 c.348G>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620589 c.699G>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620670 c.780C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620685 c.795G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620781 c.891C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620829 c.939G>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.92 capreomycin
amikacin
kanamycin
Rv0565c 657183 c.288G>A synonymous_variant 1.0 ethionamide
Rv0565c 657189 c.282C>A synonymous_variant 1.0 ethionamide
Rv0565c 657193 p.Met93Thr missense_variant 1.0 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 1.0 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 1.0 ethionamide Uncertain significance
Rv0565c 657210 c.261C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657213 c.258C>T synonymous_variant 1.0 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 1.0 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 1.0 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
Rv0565c 657252 c.219G>C synonymous_variant 1.0 ethionamide
Rv0565c 657255 c.216G>A synonymous_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657272 c.199C>T synonymous_variant 1.0 ethionamide
Rv0565c 657294 c.177C>A synonymous_variant 1.0 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 1.0 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 1.0 ethionamide
Rv0565c 657312 c.159C>T synonymous_variant 1.0 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 1.0 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.93 ethionamide
Rv0565c 657644 c.-174G>C upstream_gene_variant 0.95 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 0.95 ethionamide
Rv0565c 657668 c.-198C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657695 c.-225C>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657704 c.-234G>A upstream_gene_variant 0.97 ethionamide
Rv0565c 657725 c.-255G>A upstream_gene_variant 0.96 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 0.93 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.88 ethionamide
hadA 731687 c.-243_-237delGCAAGACinsATGTGCAT upstream_gene_variant 0.93 isoniazid
hadA 731695 c.-235C>T upstream_gene_variant 0.87 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 0.89 isoniazid
hadA 731708 c.-222G>A upstream_gene_variant 0.87 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.88 isoniazid
hadA 731726 c.-204C>G upstream_gene_variant 0.91 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.91 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.89 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 0.88 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.92 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.9 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.93 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.92 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.94 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.86 isoniazid
hadA 732305 c.376_378delATCinsGG frameshift_variant&missense_variant 0.83 isoniazid Uncertain significance
hadA 732308 p.Val127Ile missense_variant 0.83 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.79 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.8 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.8 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.86 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.91 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.94 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.95 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.94 isoniazid
nusG 734078 c.-176C>G upstream_gene_variant 0.7 rifampicin Uncertain significance
nusG 734093 c.-161A>G upstream_gene_variant 0.71 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.83 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.83 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.83 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.87 rifampicin
nusG 734142 c.-112_-110delGCGinsATA upstream_gene_variant 0.83 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.83 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 0.83 rifampicin
nusG 734153 c.-101C>A upstream_gene_variant 0.83 rifampicin
nusG 734171 c.-83_-82insG upstream_gene_variant 0.67 rifampicin
nusG 734175 c.-79G>T upstream_gene_variant 0.67 rifampicin
nusG 734177 c.-76delG upstream_gene_variant 0.71 rifampicin
nusG 734183 c.-71C>T upstream_gene_variant 0.78 rifampicin
nusG 734203 c.-51_-50delTGinsCC upstream_gene_variant 0.79 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 0.77 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.77 rifampicin
nusG 734224 c.-30G>C upstream_gene_variant 0.75 rifampicin
nusG 734225 c.-29C>T upstream_gene_variant 0.75 rifampicin
nusG 734229 c.-25A>T upstream_gene_variant 0.75 rifampicin
nusG 734230 c.-24G>A upstream_gene_variant 0.75 rifampicin
nusG 734233 c.-21T>C upstream_gene_variant 0.75 rifampicin
nusG 734236 c.-18C>T upstream_gene_variant 0.75 rifampicin
nusG 734247 c.-7G>C upstream_gene_variant 0.69 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.8 rifampicin
nusG 734373 c.120G>C synonymous_variant 0.83 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.94 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.94 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.96 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.97 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.97 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.96 rifampicin
nusG 734520 c.267C>A synonymous_variant 0.96 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.97 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734814 c.561G>C synonymous_variant 0.93 rifampicin
nusG 734820 c.567A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 0.95 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>T synonymous_variant 0.94 rifampicin
nusG 734853 c.600A>G synonymous_variant 0.95 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.95 rifampicin
nusG 734870 p.Ser206Asn missense_variant 0.95 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.96 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.97 rifampicin
nusG 734913 c.660C>G synonymous_variant 0.97 rifampicin
nusG 734931 c.678A>T synonymous_variant 0.93 rifampicin
nusG 734940 c.687G>A synonymous_variant 0.95 rifampicin
nusG 734943 c.690G>C synonymous_variant 0.94 rifampicin
nusG 734950 p.Gly233Thr missense_variant 0.93 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.89 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760112 c.306T>C synonymous_variant 0.93 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.93 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.93 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.93 rifampicin
rpoB 760181 c.375T>A synonymous_variant 0.96 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 0.96 rifampicin
rpoB 760295 c.489C>T synonymous_variant 0.94 rifampicin
rpoB 760307 c.501T>C synonymous_variant 0.94 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.94 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.92 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.94 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.93 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760358 c.552C>G synonymous_variant 0.96 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.96 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.96 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>T synonymous_variant 0.94 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.92 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.94 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>G synonymous_variant 0.95 rifampicin
rpoB 760520 c.714C>G synonymous_variant 0.96 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760526 c.720G>A synonymous_variant 0.96 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.93 rifampicin Uncertain significance
rpoB 760589 c.783C>G synonymous_variant 0.97 rifampicin
rpoB 760591 p.Val262Ala missense_variant 0.94 rifampicin
rpoB 760601 c.795C>T synonymous_variant 0.96 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760622 c.816C>T synonymous_variant 0.96 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.97 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.98 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760757 c.951T>C synonymous_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760886 c.1080A>G synonymous_variant 0.98 rifampicin
rpoB 760916 c.1110C>G synonymous_variant 0.98 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.98 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.98 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.98 rifampicin
rpoB 760937 c.1131G>A synonymous_variant 0.98 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 1.0 rifampicin
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.97 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.97 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.97 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.97 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.97 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 1.0 rifampicin
rpoB 761192 c.1386C>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 1.0 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.98 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.98 rifampicin
rpoB 761432 c.1626C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761435 c.1629T>C synonymous_variant 0.97 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.97 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.97 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.97 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.94 rifampicin
rpoB 761465 c.1659G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761471 c.1665C>T synonymous_variant 0.93 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 0.95 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.93 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.92 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.94 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>A synonymous_variant 0.98 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 0.98 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.98 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.98 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.93 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.97 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.95 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.95 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.94 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.96 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 0.98 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.96 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 0.97 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.97 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.98 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.98 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.98 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.93 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.93 rifampicin
rpoB 761913 c.2107_2109delGACinsCA frameshift_variant&missense_variant 0.93 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.93 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.94 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.94 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.99 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.99 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.98 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.98 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>T synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.98 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.98 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.98 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.98 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.98 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.98 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.98 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.98 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.98 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762431 c.2625C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.98 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.96 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.96 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.96 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.96 rifampicin
rpoC 762563 c.-807G>A upstream_gene_variant 0.94 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.9 rifampicin
rpoC 762587 c.-783G>A upstream_gene_variant 0.87 rifampicin
rpoC 762776 c.-594C>A upstream_gene_variant 0.86 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762795 p.Asp997Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762902 c.-468C>T upstream_gene_variant 0.98 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 0.98 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 0.98 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.98 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.98 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.98 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.98 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.98 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763241 c.-129G>A upstream_gene_variant 1.0 rifampicin
rpoC 763250 c.-120C>T upstream_gene_variant 1.0 rifampicin
rpoC 763253 c.-117G>T upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 1.0 rifampicin
rpoC 763265 c.-105G>A upstream_gene_variant 1.0 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 0.97 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.97 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.98 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.98 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.98 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.98 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763726 c.357C>T synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.98 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.99 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763771 c.402C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763780 c.411C>G synonymous_variant 0.98 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.98 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.98 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 0.98 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 0.95 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.96 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.96 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.96 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.96 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.96 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.96 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.96 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.96 rifampicin
rpoC 763936 c.567C>G synonymous_variant 0.95 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.97 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.97 rifampicin
rpoC 763963 c.594C>G synonymous_variant 0.97 rifampicin
rpoC 763967 p.Gly200Ser missense_variant 0.97 rifampicin
rpoC 763972 c.603C>T synonymous_variant 0.97 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.98 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.98 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.98 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.95 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.97 rifampicin
rpoC 764044 c.675T>G synonymous_variant 0.97 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.98 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.98 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764146 c.777G>A synonymous_variant 1.0 rifampicin
rpoC 764159 c.790C>T synonymous_variant 1.0 rifampicin
rpoC 764167 c.798G>A synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764218 c.849C>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>A synonymous_variant 1.0 rifampicin
rpoC 764246 c.877_879delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.97 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.97 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.97 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.98 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.98 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.98 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.96 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.93 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.95 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.95 rifampicin
rpoC 764605 c.1236G>A synonymous_variant 0.97 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.98 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 0.98 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.98 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.92 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.94 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 0.94 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.95 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.97 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1686delTCCinsAGT synonymous_variant 0.92 rifampicin
rpoC 765065 c.1696C>T synonymous_variant 0.92 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.92 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 0.85 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765223 c.1854G>C synonymous_variant 0.93 rifampicin
rpoC 765233 c.1864_1866delGCCinsTG frameshift_variant&missense_variant 0.93 rifampicin
rpoC 765247 c.1878C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765248 c.1879T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 765251 c.1882_1884delAGCinsTCG synonymous_variant 0.82 rifampicin
rpoC 765278 c.1909C>T synonymous_variant 0.9 rifampicin
rpoC 765283 c.1914C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765292 c.1923G>T synonymous_variant 0.94 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.95 rifampicin Uncertain significance
rpoC 765316 c.1947G>A synonymous_variant 0.94 rifampicin
rpoC 765328 p.His653Gln missense_variant 0.94 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.89 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 0.97 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.97 rifampicin Uncertain significance
rpoC 765391 c.2022C>T synonymous_variant 0.98 rifampicin
rpoC 765406 c.2037G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765409 c.2040T>C synonymous_variant 0.98 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.98 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.98 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.95 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 0.94 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.95 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.93 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.91 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.94 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.94 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.97 rifampicin
rpoC 765625 c.2256C>T synonymous_variant 0.96 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 0.97 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 0.98 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.98 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.96 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.98 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.98 rifampicin
rpoC 765811 c.2442T>A synonymous_variant 0.98 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.97 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.97 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.97 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.98 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.98 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.95 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.92 rifampicin
rpoC 766093 c.2724C>A synonymous_variant 0.92 rifampicin
rpoC 766095 p.Thr909Ser missense_variant 0.92 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.88 rifampicin
rpoC 766123 c.2754C>A synonymous_variant 0.86 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.85 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 766270 c.2901G>C synonymous_variant 0.77 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.79 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.79 rifampicin
rpoC 766280 c.2911_2913delAGCinsGT frameshift_variant&missense_variant 0.81 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.88 rifampicin
rpoC 766309 c.2940G>A synonymous_variant 0.94 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.95 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.98 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 1.0 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 1.0 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 1.0 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.98 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 1.0 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 1.0 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.98 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.98 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.95 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 0.95 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.95 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.95 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.95 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.95 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 0.94 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.94 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.94 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.96 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.96 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 0.96 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.91 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 0.88 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.87 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.87 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.87 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.87 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 0.88 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>G synonymous_variant 0.98 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.97 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.98 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.95 rifampicin
rpoC 767149 c.3780C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>A synonymous_variant 0.9 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.93 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>G synonymous_variant 0.93 rifampicin
rpoC 767264 p.Ala1299Gln missense_variant 0.93 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.92 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.92 rifampicin
mmpL5 775961 c.2520C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 1.0 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776030 c.2451G>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776036 c.2445G>T synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776039 c.2442C>G synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>T synonymous_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>T synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>G synonymous_variant 1.0 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.98 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.98 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.98 streptomycin
rpsL 781883 c.324G>A synonymous_variant 0.96 streptomycin
rpsL 781886 c.327C>T synonymous_variant 0.96 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.96 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.96 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.96 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.97 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.96 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 0.94 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.96 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.94 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.97 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.96 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 0.97 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.94 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.94 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 0.94 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.94 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.96 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.96 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.97 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.96 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.96 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.93 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.93 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.89 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 0.86 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.9 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.88 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 0.71 linezolid
rplC 800806 c.-3G>T upstream_gene_variant 0.71 linezolid
rplC 800807 c.-2_-1insT upstream_gene_variant 0.77 linezolid
rplC 800814 c.6A>G synonymous_variant 0.77 linezolid
rplC 800815 c.7C>A synonymous_variant 0.79 linezolid
rplC 800820 c.12G>A synonymous_variant 0.81 linezolid
rplC 800829 c.21C>G synonymous_variant 0.89 linezolid
rplC 800844 c.36T>C synonymous_variant 0.93 linezolid
rplC 800856 c.48A>G synonymous_variant 0.92 linezolid
rplC 800865 c.57A>G synonymous_variant 0.91 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.95 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.95 linezolid
rplC 800877 c.69A>C synonymous_variant 0.9 linezolid
rplC 800880 c.72A>G synonymous_variant 0.95 linezolid
rplC 800901 c.93C>G synonymous_variant 0.96 linezolid
rplC 800910 c.102C>T synonymous_variant 0.9 linezolid
rplC 800913 c.105G>A synonymous_variant 0.95 linezolid
rplC 800916 c.108A>G synonymous_variant 0.94 linezolid
rplC 800919 c.111C>G synonymous_variant 0.94 linezolid
rplC 800931 c.123G>C synonymous_variant 0.92 linezolid
rplC 800934 c.126C>G synonymous_variant 0.82 linezolid
rplC 800937 c.129A>G synonymous_variant 0.9 linezolid
rplC 801222 c.414T>C synonymous_variant 0.85 linezolid
rplC 801228 c.420T>C synonymous_variant 0.86 linezolid
rplC 801231 c.423C>T synonymous_variant 0.88 linezolid
rplC 801246 c.438C>T synonymous_variant 0.89 linezolid
rplC 801255 c.447C>A synonymous_variant 0.94 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801285 c.477G>A synonymous_variant 1.0 linezolid
rplC 801309 c.501C>G synonymous_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
rplC 801330 c.522G>T synonymous_variant 1.0 linezolid
rplC 801333 c.525G>C synonymous_variant 1.0 linezolid
rplC 801339 c.531T>G synonymous_variant 0.92 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.92 linezolid
rplC 801348 c.540T>G synonymous_variant 0.92 linezolid
rplC 801349 p.Leu181Val missense_variant 0.92 linezolid
rplC 801357 c.549T>C synonymous_variant 0.92 linezolid
rplC 801372 c.564G>A synonymous_variant 0.94 linezolid
fbiC 1303449 c.519C>T synonymous_variant 0.75 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303470 c.540T>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303538 p.Arg203Leu missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303596 c.666G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303629 c.699C>T synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303755 c.825T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304472 c.1542T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304478 c.1548G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304481 c.1551T>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>A synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 0.89 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304502 c.1572G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304532 c.1602G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304541 c.1611C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>A synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>A synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fbiC 1304712 c.1782C>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304718 c.1788C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.82 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>G synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1304760 c.1830G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304772 c.1842C>T synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304778 c.1848T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304797 p.Ala623Asn missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.95 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 0.96 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304871 c.1941G>T synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1943delAGinsTC synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304982 c.2052G>A synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>A synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1305039 c.2109G>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305354 c.2424C>T synonymous_variant 0.85 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305357 c.2427C>G synonymous_variant 0.86 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305361 c.2431C>T synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1305414 c.2484G>A synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1305426 c.2496G>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1305427 c.2497C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1305435 c.2505G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1305446 p.Gly839Ala missense_variant 0.73 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
sigE 1364703 c.291G>C synonymous_variant 0.89 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.83 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.81 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 0.87 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.87 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.87 pyrazinamide
sigE 1364745 c.333C>T synonymous_variant 0.87 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
sigE 1364751 c.339C>G synonymous_variant 0.89 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.92 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.92 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.96 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.96 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.96 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.95 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.9 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.9 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.87 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.86 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.84 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 0.76 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 0.73 pyrazinamide
sigE 1364874 c.462C>T synonymous_variant 0.73 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.73 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
sigE 1364892 c.480C>G synonymous_variant 0.73 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.85 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.87 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 0.87 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.94 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 0.85 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.92 pyrazinamide
sigE 1364964 c.552T>G synonymous_variant 0.92 pyrazinamide
sigE 1364967 c.555C>T synonymous_variant 0.92 pyrazinamide
sigE 1364973 c.561G>A synonymous_variant 0.92 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
sigE 1364980 c.568T>C synonymous_variant 0.92 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.92 pyrazinamide
sigE 1364988 c.576G>A synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
sigE 1365003 c.591T>C synonymous_variant 0.92 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.92 pyrazinamide
embR 1416285 p.Glu355Gln missense_variant 0.9 ethambutol
embR 1416289 c.1059G>A synonymous_variant 0.91 ethambutol
embR 1416301 c.1047C>A synonymous_variant 0.94 ethambutol
embR 1416310 c.1038G>C synonymous_variant 0.95 ethambutol
embR 1416313 c.1035A>G synonymous_variant 1.0 ethambutol
embR 1416316 c.1032C>G synonymous_variant 1.0 ethambutol
embR 1416330 p.Val340Ile missense_variant 1.0 ethambutol
embR 1416332 p.Tyr339Phe missense_variant 1.0 ethambutol
embR 1416335 p.Asn338Ser missense_variant 1.0 ethambutol
embR 1416343 c.1005G>C synonymous_variant 1.0 ethambutol
embR 1416364 c.984C>T synonymous_variant 0.95 ethambutol
atpE 1460807 c.-238C>T upstream_gene_variant 0.96 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 0.94 bedaquiline
atpE 1460828 c.-217C>T upstream_gene_variant 0.95 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 0.95 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
atpE 1460882 c.-163T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460894 c.-151A>G upstream_gene_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.96 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.98 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.96 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 0.89 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 0.93 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 0.93 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 0.88 capreomycin
linezolid
rrl 1473449 n.-209G>A upstream_gene_variant 0.81 capreomycin
linezolid
rrl 1473454 n.-204A>G upstream_gene_variant 0.8 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473918 n.261C>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473943 n.286G>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsAT non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1473994 n.337C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474011 n.354G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474018 n.361G>A non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474030 n.373G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474110 n.453A>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474409 n.756_774delACCCACACGCGCATACGCG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474433 n.776G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474435 n.779_783delTGAAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474945 n.1288C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475007 n.1350C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475018 n.1361G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475404 n.1747A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.94 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.89 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.92 capreomycin
linezolid
inhA 1673475 c.-727A>C upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673499 c.-703T>C upstream_gene_variant 0.97 ethionamide
isoniazid Uncertain significance
inhA 1673505 c.-697A>T upstream_gene_variant 0.97 ethionamide
isoniazid
inhA 1673517 c.-685G>C upstream_gene_variant 0.9 ethionamide
isoniazid
inhA 1673524 c.-678C>T upstream_gene_variant 0.95 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.94 ethionamide
isoniazid
inhA 1673565 c.-637G>C upstream_gene_variant 0.96 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.95 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.93 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.91 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.91 ethionamide
isoniazid
inhA 1673604 c.-598G>C upstream_gene_variant 0.91 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.93 ethionamide
isoniazid
fabG1 1673615 p.Glu59Val missense_variant 0.95 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.89 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.7 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673697 c.-505G>C upstream_gene_variant 0.86 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.85 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.85 ethionamide
isoniazid
inhA 1673724 c.-478A>C upstream_gene_variant 0.92 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673730 c.-472C>G upstream_gene_variant 0.92 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.92 ethionamide
isoniazid
inhA 1673745 c.-457G>A upstream_gene_variant 0.85 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.85 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.85 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.85 ethionamide
isoniazid
inhA 1673865 c.-337C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 1.0 ethionamide
isoniazid
inhA 1673877 c.-325C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674471 c.270G>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.95 ethionamide
isoniazid
inhA 1674507 c.306G>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 0.97 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674537 c.336C>A synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.97 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.98 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674588 c.387G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 0.97 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674619 p.Pro140Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674687 c.486G>A synonymous_variant 0.93 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674690 c.489C>G synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674696 c.495G>A synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674717 c.516C>T synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674729 c.528G>A synonymous_variant 0.91 ethionamide
isoniazid
inhA 1674745 p.Tyr182Ala missense_variant 0.86 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.85 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674777 c.576C>A synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674820 c.619_621delCTCinsTG frameshift_variant&missense_variant 0.82 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.85 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.9 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674888 c.687C>T synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 0.98 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674939 c.738G>A synonymous_variant 0.97 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674942 c.741T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 0.97 ethionamide
isoniazid
inhA 1675008 c.807C>G synonymous_variant 0.96 ethionamide
isoniazid
rpsA 1833256 c.-286C>G upstream_gene_variant 0.74 pyrazinamide
rpsA 1833262 c.-280T>C upstream_gene_variant 0.76 pyrazinamide
rpsA 1833273 c.-269G>A upstream_gene_variant 0.8 pyrazinamide
rpsA 1833277 c.-265C>G upstream_gene_variant 0.82 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 0.83 pyrazinamide
rpsA 1833288 c.-254_-253delTGinsCC upstream_gene_variant 0.83 pyrazinamide
rpsA 1833304 c.-238C>G upstream_gene_variant 0.74 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.73 pyrazinamide
rpsA 1833319 c.-223C>G upstream_gene_variant 0.73 pyrazinamide
rpsA 1833340 c.-202G>C upstream_gene_variant 0.79 pyrazinamide
rpsA 1833343 c.-199G>C upstream_gene_variant 0.75 pyrazinamide
rpsA 1833352 c.-190C>G upstream_gene_variant 0.73 pyrazinamide
rpsA 1833532 c.-10A>C upstream_gene_variant 0.9 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.94 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.94 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 0.94 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.94 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.95 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
rpsA 1833790 c.249T>C synonymous_variant 0.96 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.96 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.96 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.97 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833895 c.354G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.98 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833970 c.429G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.94 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.96 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834474 c.933C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.98 pyrazinamide
rpsA 1834603 c.1062G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 0.98 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 0.96 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.92 pyrazinamide
tsnR 1853369 c.-237C>T upstream_gene_variant 0.93 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.93 linezolid
tsnR 1853375 c.-231G>A upstream_gene_variant 0.93 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.93 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.93 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.93 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 0.88 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.88 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.88 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.79 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.77 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 0.75 linezolid
ndh 2101873 c.1170T>C synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2101879 c.1164C>T synonymous_variant 0.91 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102878 c.165G>C synonymous_variant 0.85 ethionamide
delamanid
isoniazid
ndh 2102883 c.160C>T synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2102895 c.148C>T synonymous_variant 0.91 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102902 c.141C>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102908 c.135C>G synonymous_variant 0.92 ethionamide
delamanid
isoniazid
ndh 2102914 c.129C>T synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102919 c.124C>T synonymous_variant 0.96 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102938 p.Arg35His missense_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102959 c.84C>T synonymous_variant 0.96 ethionamide
delamanid
isoniazid
ndh 2102962 c.81A>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102971 c.72C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102977 c.66T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
katG 2155017 c.1095G>C synonymous_variant 1.0 isoniazid
katG 2155026 c.1086C>G synonymous_variant 1.0 isoniazid
katG 2155047 c.1065C>G synonymous_variant 0.96 isoniazid
katG 2155054 p.Tyr353Phe missense_variant 0.96 isoniazid
katG 2155056 c.1056A>G synonymous_variant 0.96