Run ID: SRR3675495
Sample name:
Date: 2024-03-25T19:37:43.215682
Number of reads: 457365
Percentage reads mapped: 22.05
Median coverage: 3.0
Strain: lineage2.1;lineage4.9
Spoligotype:
Drug-resistance: RR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.96 |
| lineage2.1 | East-Asian (non-Beijing) | None | 0.05 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.9 |
| La1.7.X-unk4 | M.bovis | None | 0.06 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fbiC | c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
| fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 1.0 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 927 | c.927G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 933 | c.933C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 942 | c.942C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 948 | c.948C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 955 | c.955A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 963 | c.963C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 966 | c.966T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 975 | c.975G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 984 | c.984T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 987 | c.987C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 990 | c.990A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1003 | c.1003C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1008 | c.1008G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1014 | c.1014C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1020 | c.1020C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1023 | c.1023C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1024 | c.1024T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1050 | c.1050G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1056 | c.1056G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1059 | c.1059C>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1077 | c.1077A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1110 | c.1110T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1119 | c.1119G>A | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6145 | c.906C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6160 | c.921C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6184 | c.945C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6190 | c.951A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6196 | c.957C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6202 | c.963C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6203 | p.Ser322Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6211 | c.972G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6217 | c.978G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6220 | c.981G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6223 | c.984G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6235 | c.996C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6244 | c.1005C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6247 | c.1008G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6256 | c.1017G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6268 | c.1029C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6298 | c.1059C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6299 | c.1060C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 6325 | c.-977C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6326 | p.Ser363Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6358 | c.1119C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6362 | c.1123_1125delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6367 | c.-935C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6376 | c.-926G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6571 | c.-731T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6583 | c.-719G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6592 | c.-710C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6595 | c.1356G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6610 | c.-692C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6613 | c.-689A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6628 | c.-674C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6640 | c.-662A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6646 | c.-656C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6664 | c.1425C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6742 | c.-560A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6749 | p.Ala504Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6766 | c.-536G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6805 | c.1566G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6824 | c.1585C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6850 | c.-452C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6865 | c.-437G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6866 | c.-436C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6869 | c.-433T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6872 | c.-430T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6910 | c.-392G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6919 | c.1680T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6955 | c.-347G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6978 | p.Phe580Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6991 | c.-311C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6994 | c.-308C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6997 | c.-305G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7015 | c.-287G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7018 | c.-284G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7027 | c.-275G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7057 | c.1818C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7075 | c.-227T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7076 | c.1837_1839delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7114 | c.-188C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7136 | c.1897_1899delTTGinsCA | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7153 | c.1914G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7168 | c.-134C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7171 | c.-131C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7177 | c.-125G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7178 | c.1939_1941delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 7186 | c.1947C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7192 | c.-110G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7213 | c.-89G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7219 | c.-83C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7240 | c.2001C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7252 | c.-50G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7258 | c.-44G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7261 | c.-41T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7266 | c.2027_*9delAACGCAACCCTinsGATCG | stop_lost&splice_region_variant&stop_retained_variant&intron_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7280 | c.-22T>G | upstream_gene_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 7307 | c.6A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7418 | c.117C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7430 | c.129G>A | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7448 | c.147G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7502 | c.201C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7553 | c.252C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7568 | c.267C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7614 | p.Leu105Met | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7619 | c.318C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCT | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7775 | c.474C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7797 | c.496_498delCTAinsTG | frameshift_variant&stop_gained | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7811 | c.510C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7814 | c.513C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8253 | p.Ile318Leu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8258 | c.957G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | p.Ile328Leu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8342 | c.1041G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8345 | c.1044C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8360 | c.1059G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8369 | c.1068G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8378 | c.1077C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8393 | c.1092T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8405 | c.1104C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8408 | c.1107A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8417 | c.1116C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8433 | p.Thr378Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8513 | c.1212C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8531 | c.1230G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8534 | c.1233G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8540 | c.1239C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8556 | p.Ala419Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8580 | p.Ile427Val | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8645 | c.1344C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8696 | c.1395G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8706 | c.1405C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8726 | c.1425G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8730 | c.1429_1431delGGGinsCA | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8747 | c.1446A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8750 | c.1449C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8783 | c.1482G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 0.9 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8882 | c.1581G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8924 | c.1623C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8927 | c.1626G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8930 | c.1629C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8933 | c.1632G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8939 | c.1638T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8945 | c.1644G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8975 | c.1674C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9016 | p.Thr572Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9063 | p.Ser588Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9086 | c.1785C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9089 | c.1788G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9113 | c.1812C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9139 | p.Gln613Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9147 | p.Gly616Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9167 | c.1866C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9174 | c.1873C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>G | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9191 | c.1890G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9192 | c.1891C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9208 | p.Lys636Arg | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9212 | c.1911G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9218 | p.Asp639Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9224 | c.1923C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9245 | c.1944C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9275 | c.1974G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9278 | c.1977G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9332 | c.2031C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9356 | c.2055G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9358 | p.Thr686Asn | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9365 | c.2064G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9369 | c.2068C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 491115 | c.333G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491133 | c.351A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491185 | p.Ser135Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491217 | c.435T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491223 | c.441C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491226 | c.444C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491249 | p.Arg156His | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491262 | c.480C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491277 | c.495G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491289 | c.507C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491302 | p.Ile174Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491310 | c.528C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491331 | c.549G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491340 | c.558C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491343 | c.561C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491355 | c.573C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491556 | c.774G>A | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491559 | c.777G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491595 | c.813C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575752 | c.405G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575756 | c.409C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575764 | c.417C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575767 | c.420G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575772 | p.Val142Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575788 | c.441C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| ccsA | 620326 | c.436C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620349 | c.459A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620676 | c.786C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620685 | c.795G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620697 | c.807C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620712 | c.822G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| hadA | 731753 | c.-177A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| nusG | 734466 | c.213G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734505 | c.252G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734514 | c.261A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734517 | c.264G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734565 | c.312G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734566 | c.313C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734571 | c.318C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760106 | c.300G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760136 | c.330G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760139 | c.333A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760174 | p.Tyr123Phe | missense_variant | 1.0 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760199 | c.393C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760223 | c.417T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760253 | c.447T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760274 | c.468G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760307 | c.501T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760389 | c.583_585delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760403 | c.597C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760436 | c.630C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760451 | c.645C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760493 | c.687C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760497 | c.691C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760526 | c.720G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760597 | p.Thr264Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 760604 | p.Glu266Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 760608 | c.802C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760634 | c.828T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760643 | c.837G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760916 | c.1110C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760971 | c.1165C>A | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761006 | c.1200C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761054 | c.1248G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761111 | c.1305C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761147 | c.1341C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761153 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761162 | c.1356G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761180 | c.1374A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761183 | c.1377T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761217 | p.Pro471Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761220 | c.1414_1416delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761274 | c.1468C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761314 | p.Phe503Tyr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761324 | c.1518C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761333 | c.1527G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761349 | p.Asp515Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761405 | c.1599C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761437 | p.Ala544Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761441 | c.1635C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761451 | p.Val549Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761462 | c.1656C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761471 | c.1665C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761482 | p.Ala559Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 761486 | c.1680C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761502 | p.Pro566Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761507 | c.1701G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761633 | c.1827G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761640 | c.1834C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761657 | c.1851C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761681 | c.1875G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761682 | c.1876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761714 | c.1908C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761723 | p.Glu639Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoB | 761726 | p.Glu640Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761736 | p.Ile644Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761765 | c.1959T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761828 | c.2022C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761847 | p.Cys681Arg | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761867 | c.2061C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761876 | c.2070C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761903 | c.2097T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761945 | c.2139G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761951 | c.2145G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761972 | c.2166C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761997 | c.2191_2193delCTGinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762008 | c.2202C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762011 | c.2205G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762024 | c.2218_2220delGTGinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762050 | c.2244G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762110 | c.2304G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762114 | p.Ile770Val | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoB | 762122 | c.2316C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 762149 | c.2343G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762192 | c.2386C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 762218 | c.2412T>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762297 | c.2491C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762410 | c.2604T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762482 | c.-888C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762491 | c.2685T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762537 | c.2731_2733delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 762542 | c.-828C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762548 | c.2742C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762551 | c.-819C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762581 | c.-789T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762605 | c.-765T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762624 | p.Val940Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762814 | p.Met1003Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762831 | c.3025_3026delAGinsTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762899 | c.3093G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762995 | c.3189G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763053 | c.3247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763058 | c.-312C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763082 | c.-288C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763139 | c.-231C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763441 | c.72C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763489 | c.120G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763552 | c.183C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R |
| rpoC | 763561 | c.192G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763570 | c.201G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763606 | c.237C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763609 | c.240C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763615 | c.246G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763654 | c.285C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763669 | c.300C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763726 | c.357C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763727 | c.358C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763732 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763735 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763768 | c.399C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 763771 | c.402C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763774 | c.405G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763781 | p.Ser138Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763796 | p.Met143Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763978 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764027 | p.Glu220Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764039 | p.Ser224Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764068 | c.699G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764147 | p.Ser260Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764161 | c.792G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764195 | p.Ser276Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764209 | c.840C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764245 | c.876C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764255 | c.886C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764266 | c.897T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764269 | c.900G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764285 | p.Gly306Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 764317 | c.948C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764344 | c.975C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764383 | c.1014C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764386 | c.1017C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764500 | c.1131C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764570 | c.1203_1204delGC | frameshift_variant | 1.0 | rifampicin | |
| rpoC | 764577 | c.1208_1209delCCinsGAGT | frameshift_variant&stop_gained | 1.0 | rifampicin | |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764656 | c.1287C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764680 | c.1311G>A | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764695 | c.1326T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764713 | c.1344G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764755 | c.1386C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764770 | c.1401G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 764782 | c.1413C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764812 | c.1443C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764861 | c.1492C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764875 | c.1506C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764902 | c.1533C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764918 | c.1549_1551delGTGinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764932 | c.1563C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764986 | c.1617C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765053 | c.1684_1685delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765122 | c.1753C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765145 | c.1776C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765391 | c.2022C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765394 | c.2025G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765404 | p.Leu679Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765415 | c.2046G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765452 | p.Ala695Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765544 | c.2175C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765547 | c.2178C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765548 | c.2179_2180delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765590 | p.Arg741Asn | missense_variant | 1.0 | rifampicin | |
| rpoC | 765596 | p.Lys743Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765655 | c.2286T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765724 | c.2355C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765751 | c.2382C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765781 | p.Asp804Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765823 | c.2454C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765826 | c.2457T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765835 | c.2466C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765836 | c.2467C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765865 | c.2496C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765871 | c.2502T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765908 | c.2539C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766163 | c.2794_2796delGAGinsAA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766167 | p.Ala933Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 766189 | c.2820T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766194 | p.Gln942Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 766207 | c.2838T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766411 | c.3042C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766442 | p.Thr1025Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 766445 | c.3076_3078delGGTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766484 | c.3115_3117delGTAinsAT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766518 | p.Thr1050Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766534 | c.3165C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766546 | p.Glu1059Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766570 | c.3201T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766618 | c.3249G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766633 | c.3264G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766652 | p.Ser1095Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766667 | p.Ser1100Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766684 | c.3315C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766750 | c.3381C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766775 | p.Arg1136Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766787 | p.Glu1140Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766807 | c.3438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766834 | c.3465G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766843 | c.3474T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766867 | c.3498C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766921 | c.3552G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766933 | c.3564A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766942 | c.3573C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766988 | c.3619C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767066 | c.3697C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767162 | p.Asn1265Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767239 | c.3870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767264 | p.Ala1299Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767278 | c.3909T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767281 | c.3912C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767302 | c.3933C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767306 | p.Ser1313Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 767320 | c.3951G>A | splice_region_variant&stop_retained_variant | 1.0 | rifampicin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781634 | c.75G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781652 | c.93T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781703 | c.144G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781715 | c.156T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781724 | c.165G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781733 | c.174G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781778 | c.219C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781779 | c.220C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781799 | c.240G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781820 | c.261G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781826 | c.267C>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781856 | c.297C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rplC | 800570 | c.-239C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800574 | c.-235_-233delGTCinsAG | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800579 | c.-230C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800594 | c.-215C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800597 | c.-212A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800603 | c.-206G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800630 | c.-179G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800633 | c.-176T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800657 | c.-152G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 801195 | c.387G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801201 | c.393C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801210 | c.402T>G | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 801216 | c.408C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801222 | c.414T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801231 | c.423C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801234 | c.426G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801237 | c.429G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801246 | c.438C>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801249 | c.441T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801252 | c.444G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801258 | c.450C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801264 | c.456C>G | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 801267 | c.459A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801276 | c.468G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801282 | c.474G>C | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1304481 | c.1551T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304496 | c.1566T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304511 | c.1581C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304517 | c.1587C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304520 | c.1590A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304526 | c.1596T>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304532 | c.1602G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304533 | c.1603T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304538 | c.1608C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304545 | p.Val539Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304568 | c.1638T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304571 | c.1641G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304574 | c.1644C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305012 | c.2082G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305024 | c.2094C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305030 | c.2100G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305043 | c.2113_2115delTCAinsAGC | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305066 | c.2136T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305069 | c.2139G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305075 | c.2145T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305078 | c.2148A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305081 | c.2151G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305090 | c.2160C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305096 | c.2166T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305099 | c.2169T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305126 | c.2196T>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305135 | c.2205C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305150 | c.2220C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305162 | c.2232C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305174 | c.2244T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305177 | c.2247A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305181 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305186 | c.2256C>T | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305195 | c.2265T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305204 | c.2274C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305210 | c.2280G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305234 | c.2304G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305237 | c.2307A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305243 | c.2313T>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305270 | c.2340C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305276 | c.2346G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305297 | c.2367G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305300 | c.2370A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305303 | c.2373T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305306 | c.2376A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305311 | p.Arg794Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305313 | p.Arg795Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305324 | c.2394G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305336 | c.2406T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305393 | c.2463T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305405 | c.2475A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364676 | c.264C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364679 | c.267T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364688 | c.276C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364691 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364697 | c.285G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364709 | c.297T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364712 | c.300T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364718 | c.306C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364721 | c.309C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364778 | c.366G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364784 | c.372C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364799 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364805 | c.393C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364835 | c.423C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364856 | c.444C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364865 | c.453G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364866 | p.Ala152Ser | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364875 | c.463C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364883 | c.471G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364889 | c.477A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364898 | c.486C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364918 | p.Asp169Ala | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364952 | c.540A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364956 | c.544C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364960 | p.Gly183Ala | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364964 | c.552T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364976 | c.564T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364979 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364980 | c.568T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364984 | p.Ala191Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364994 | c.582G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365006 | c.594T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365019 | c.607C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365024 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rrs | 1471923 | n.78_81delTCTCinsCCCCTTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471929 | n.84C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471931 | n.87delA | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471936 | n.91A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471972 | n.127T>C | non_coding_transcript_exon_variant | 0.98 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472041 | n.196C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472042 | n.197T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472043 | n.198T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472055 | n.210C>T | non_coding_transcript_exon_variant | 0.38 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472057 | n.212C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472059 | n.214_215insGG | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472123 | n.278A>G | non_coding_transcript_exon_variant | 0.39 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472288 | n.443A>C | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472298 | n.453G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472300 | n.455C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472313 | n.468G>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472314 | n.469A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472326 | n.481T>G | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472382 | n.537G>A | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Not assoc w R | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472425 | n.580T>C | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472443 | n.598A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472447 | n.602C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472448 | n.603T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 0.94 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472486 | n.641A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472494 | n.649A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472674 | n.830_831delTC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472680 | n.835C>T | non_coding_transcript_exon_variant | 0.97 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472682 | n.837T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472684 | n.839_840insAA | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472845 | n.1001delC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472849 | n.1004_1005insG | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472858 | n.1013G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472861 | n.1016G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.96 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.97 | streptomycin | Uncertain significance |
| kanamycin | Not assoc w R | |||||
| capreomycin | Not assoc w R | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsGG | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473202 | n.1357C>T | non_coding_transcript_exon_variant | 0.96 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473277 | n.1432G>C | non_coding_transcript_exon_variant | 0.92 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473289 | n.1444_1445delTCinsCGTTTTG | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473300 | n.1455C>G | non_coding_transcript_exon_variant | 0.92 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.93 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1473668 | n.11C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473697 | n.40C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473699 | n.42A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473701 | n.44A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473731 | n.74T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473746 | n.89T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473768 | n.111A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473782 | n.125A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473788 | n.131A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473807 | n.150T>C | non_coding_transcript_exon_variant | 0.96 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473822 | n.165A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473823 | n.166T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473836 | n.179A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473887 | n.230T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473888 | n.231T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474180 | n.523T>G | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
| linezolid | ||||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.89 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474183 | n.526T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474185 | n.528G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474282 | n.625G>A | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474287 | n.630T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474289 | n.633_649delTTTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474310 | n.654_655dupGG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474350 | n.693G>C | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
| linezolid | ||||||
| rrl | 1474351 | n.694G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474353 | n.696A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474374 | n.717T>G | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474413 | n.756A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474414 | n.757C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474415 | n.758C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474437 | n.781_782delAA | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474447 | n.790G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474452 | n.795C>G | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
| linezolid | ||||||
| rrl | 1474467 | n.810A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474626 | n.969T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474629 | n.972G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474638 | n.981C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474639 | n.982G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474673 | n.1016T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474710 | n.1053T>G | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474711 | n.1054G>T | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474715 | n.1058T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474716 | n.1059A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474720 | n.1063C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474752 | n.1095T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474798 | n.1141C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1474901 | n.1244A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475088 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475353 | n.1696A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475369 | n.1712G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475378 | n.1721A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475379 | n.1722G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475380 | n.1723C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475397 | n.1740_1743delGCTCinsCGGCGTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475401 | n.1745_1746delCT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475425 | n.1768G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475436 | n.1779C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475479 | n.1822C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475484 | n.1827A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475532 | n.1875A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475544 | n.1887A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475612 | n.1955G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475615 | n.1958C>G | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
| linezolid | ||||||
| rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475620 | n.1963T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475621 | n.1964T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475626 | n.1969delTinsCC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475629 | n.1972G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475643 | n.1986C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475647 | n.1990G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475655 | n.1998T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475707 | n.2050T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475756 | n.2099T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1475762 | n.2105_2108delGCAAinsCGGTTTTCG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1475989 | n.2332T>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1475992 | n.2335T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476001 | n.2344T>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476025 | n.2368G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1476026 | n.2369T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476035 | n.2378G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476044 | n.2387T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476058 | n.2401T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476076 | n.2419A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476077 | n.2420T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476087 | n.2430C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476088 | n.2431A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476108 | n.2451T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476164 | n.2507A>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1476165 | n.2508T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476221 | n.2564T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476246 | n.2589G>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476252 | n.2595T>C | non_coding_transcript_exon_variant | 0.99 | capreomycin | |
| linezolid | ||||||
| rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476523 | n.2866T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 0.9 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476531 | n.2874T>C | non_coding_transcript_exon_variant | 0.89 | capreomycin | |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476629 | n.2972C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476665 | n.3008T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476666 | n.3009C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476679 | n.3022T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476691 | n.3034T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476692 | n.3035T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673865 | c.-337C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673867 | p.Gly143Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673870 | p.Ser144Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673895 | c.-307C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673910 | c.-292G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673916 | c.-286A>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673917 | c.-285G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673925 | c.-277C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673946 | c.-256C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673961 | c.-241A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673973 | c.-229G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1674033 | c.-169T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674036 | c.-166G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674037 | p.Gln200Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674042 | c.-160G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1674045 | c.-157G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674049 | p.Gln204Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674054 | c.-148T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674060 | c.-142A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674070 | c.631_633delGTCinsAT | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674079 | p.Pro214Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674096 | c.-106G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674099 | c.-103G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674243 | c.42A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674256 | p.Ser19Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1674270 | c.69T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674279 | c.78A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674282 | c.81G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674285 | c.84A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674288 | c.87C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674291 | c.90G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674303 | c.102C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674312 | c.111G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674313 | p.Leu38Cys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674321 | c.120G>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674342 | c.141T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674343 | p.Gln48Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1833559 | c.18C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833560 | p.Thr7Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833589 | c.48A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833625 | c.84A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833628 | c.87G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833658 | c.117C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833664 | c.123C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833688 | c.147C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833829 | c.288A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833832 | p.Glu97Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833850 | c.309C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833871 | c.330G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833892 | c.351G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833901 | c.360G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833904 | c.363G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833916 | c.375C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833922 | c.381G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833937 | c.396G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833952 | c.411C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833988 | c.447C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834096 | c.555G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834169 | c.628_630delACCinsGG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834174 | c.633C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834183 | c.642T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834186 | c.645C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834234 | c.693G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834237 | c.696C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834252 | c.711C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834258 | c.717G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834285 | c.744G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834297 | c.756C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834351 | c.810G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834381 | c.840G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834414 | c.873C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834495 | c.954G>A | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834519 | c.978G>C | synonymous_variant | 0.93 | pyrazinamide | |
| rpsA | 1834520 | p.Ala327Ser | missense_variant | 0.93 | pyrazinamide | |
| rpsA | 1834528 | c.987T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834532 | p.Val331Ile | missense_variant | 0.97 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834541 | p.Pro334Ala | missense_variant | 0.96 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834557 | p.Ala339Gly | missense_variant | 0.95 | pyrazinamide | |
| rpsA | 1834561 | c.1020C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834570 | p.Asp343Glu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834572 | p.Ala344Val | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834603 | c.1062G>A | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834612 | c.1071G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834654 | c.1113G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834666 | c.1125G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834669 | c.1128G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834702 | p.Gln387His | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834720 | c.1179C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Pro | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834761 | p.Phe407Tyr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155719 | c.393G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155734 | p.Met126Ala | missense_variant | 1.0 | isoniazid | |
| katG | 2155740 | p.Gly124Glu | missense_variant | 0.91 | isoniazid | |
| katG | 2155743 | c.369G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155747 | p.Ala122Gly | missense_variant | 1.0 | isoniazid | |
| katG | 2155755 | c.357C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155785 | c.327T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2517938 | c.-177C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517968 | c.-147T>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518180 | c.66G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518193 | p.Pro27Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518204 | c.90G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106_108delCTGinsTA | frameshift_variant&stop_gained | 1.0 | isoniazid | |
| kasA | 2518223 | c.109T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518234 | c.120G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518270 | c.156C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | p.Ala57Pro | missense_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518303 | c.189C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518306 | c.192C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518316 | p.Val68Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518322 | p.Ser70Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518336 | c.222A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518339 | c.225C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518343 | p.Met77Leu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518348 | c.234A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518360 | c.246C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518374 | p.Gly87Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518379 | c.265T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518386 | p.Gly91Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518390 | c.276A>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518396 | c.282A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518403 | p.Ser97Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518413 | p.Ser100Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518429 | c.315A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518439 | c.325_327delGCCinsTG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518444 | c.330T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518447 | c.333T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518448 | p.Val112Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518459 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518462 | c.348A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518465 | c.351T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518468 | c.354A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518475 | c.361_363delAGGinsCA | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518486 | c.372G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518513 | c.399C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518531 | c.417G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518537 | c.423C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518610 | p.Thr166Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518624 | c.510C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518627 | c.513T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518630 | c.516G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518636 | c.522C>T | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518654 | c.540C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518663 | c.549T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518670 | c.556_558delGTGinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518673 | p.Met187Leu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518688 | p.Val192Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518693 | c.579C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518715 | p.Pro201Gly | missense_variant | 1.0 | isoniazid | |
| kasA | 2519224 | c.1110C>G | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2519257 | c.1143C>T | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2519260 | c.1146T>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2519264 | p.Val384Ile | missense_variant | 0.92 | isoniazid | |
| kasA | 2519269 | c.1155C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2519275 | c.1161C>A | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2519281 | c.1167G>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2519287 | c.1173T>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2519291 | c.1177_1179delGATinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2519298 | p.Arg395Gln | missense_variant | 1.0 | isoniazid | |
| kasA | 2519305 | c.1191A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519306 | p.Val398Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2519323 | c.1209G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519332 | c.1218C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726303 | c.111T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726307 | p.Thr39Ser | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726312 | c.120T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726318 | p.Glu42Asp | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726319 | c.127_129delCACinsTT | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| ahpC | 2726324 | c.132A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| Rv2477c | 2782396 | c.1647G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782399 | c.1644T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782408 | c.1635T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782414 | p.Asp543Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782419 | p.Val542Ile | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782420 | c.1623T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782432 | c.1609_1611delGTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2782435 | c.1608G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782441 | c.1602G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782453 | c.1590C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782480 | c.1563G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782496 | p.Asp516Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782501 | c.1542T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782504 | c.1539G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782510 | c.1533G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782537 | c.1506T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782555 | c.1488G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782558 | c.1485T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782561 | c.1482G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782576 | c.1467C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782579 | c.1464C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782587 | p.Leu486Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782591 | c.1452T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782597 | c.1446G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782621 | c.1422T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782624 | c.1419G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782633 | c.1410G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782639 | c.1404A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782651 | c.1392T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782656 | c.1387C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782669 | c.1374A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782675 | c.1368G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782680 | c.1363T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782684 | c.1359T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782690 | c.1353C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783044 | c.999G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783047 | c.994_996delGACinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783080 | c.963G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783085 | p.Val320Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783086 | p.Asn319Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783092 | c.949_951delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783095 | c.948C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783098 | c.945C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783105 | p.Val313Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783122 | c.921G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783143 | c.900G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783146 | c.897G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | ||||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783152 | c.891G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783167 | c.876G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783181 | c.862C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783185 | c.858G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783194 | c.849A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783203 | c.840C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783206 | c.837G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783239 | c.804G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783242 | p.Thr267Gln | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783247 | c.796T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783251 | c.792G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783317 | c.726G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783335 | c.708C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783347 | c.696C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783371 | c.672A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783377 | c.666C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783386 | c.657G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783401 | c.642C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783476 | c.567C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783499 | c.544T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783505 | c.538C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783516 | c.526_527delTCinsAG | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783535 | c.508C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783557 | c.486T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783568 | p.Asn159Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783578 | c.465G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783584 | c.457_459delGCCinsCT | frameshift_variant&synonymous_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783623 | c.420G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783659 | c.384A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783673 | c.370C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783708 | p.Thr112Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783722 | c.321C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783746 | c.297G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783757 | p.Ile96Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783770 | c.273G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783773 | c.270A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783776 | c.267G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783788 | c.255T>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783806 | c.237G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | c.222A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783826 | c.217C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783836 | c.207C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783842 | c.201C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783845 | c.196_198delACCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783866 | c.177C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783917 | c.126C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783923 | c.120C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783929 | c.114C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783950 | c.93C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783962 | p.Ser27Asn | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783967 | c.76T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2784017 | p.Lys9Arg | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| pepQ | 2859798 | c.621G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859825 | c.594C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859834 | c.585T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859846 | p.Glu191Asp | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859852 | c.567A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859858 | p.Ala187Gly | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859864 | c.555T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859870 | c.549T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859873 | c.546T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| Rv2752c | 3064908 | c.1284C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064932 | c.1260T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064935 | c.1257A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064941 | c.1251A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064950 | c.1242C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064956 | c.1234_1236delAGTinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3064968 | p.Lys408Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064998 | c.1194A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065004 | c.1186_1188delGTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065013 | c.1179G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065016 | c.1176C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065055 | c.1137T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065058 | c.1134C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065061 | c.1131C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065087 | c.1105A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065094 | c.1098C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065097 | c.1095C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065106 | c.1086C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065109 | c.1081_1083delAGAinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065127 | c.1065G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065131 | p.Ala354Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065151 | c.1041G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065154 | c.1038G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065612 | p.Thr194Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065619 | c.573C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065634 | c.558G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065637 | c.555A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065640 | c.552T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065658 | p.Pro178Leu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065661 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065664 | c.526_528delTTGinsCT | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065667 | c.525A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065675 | p.Phe173Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065699 | p.Ile165Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065709 | c.483C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067706 | c.240C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067712 | c.234G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067718 | c.228C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067730 | c.216G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067733 | c.213G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067736 | c.210C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067742 | c.204A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067762 | c.184C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3624641 | c.270C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624646 | c.265T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624649 | c.262T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624656 | c.255C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624680 | c.231T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624683 | c.228G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624686 | c.223_225delGAAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624695 | c.216C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624701 | c.210T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624704 | c.207G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624728 | c.183C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624755 | c.154_156delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624776 | c.135T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624783 | p.Ser43Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624788 | c.123A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625675 | c.-765G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625711 | c.903C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625723 | c.-813C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625732 | c.882C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625759 | c.-849G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625762 | c.852A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625774 | c.840G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625777 | c.-867C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625797 | p.Val273Met | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625798 | c.-888G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625819 | c.795G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625825 | c.-915C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625846 | c.-936G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625852 | c.-942A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625864 | c.-954T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625870 | c.-960C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625989 | p.Thr209Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625990 | c.624C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625995 | c.618delC | frameshift_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3626001 | c.612dupG | frameshift_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| mtrB | 3626006 | p.Ser203Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626008 | c.606G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626029 | c.585A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626035 | c.579G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626038 | c.576C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626043 | p.Ala191Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626054 | p.Leu187Pro | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626062 | c.552T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626065 | c.549G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626077 | c.537C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626080 | c.534G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626095 | c.519A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626870 | c.480C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626897 | c.-284G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626918 | c.432G>A | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626924 | c.-311G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626927 | c.-314G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626945 | c.-332C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626983 | p.Asn123Tyr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627002 | c.-389G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627026 | c.324G>A | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627056 | c.294C>T | synonymous_variant | 0.97 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627083 | c.-470G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627119 | c.231T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627122 | c.-509T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627143 | c.-530G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627149 | c.-536G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| fbiB | 3642623 | c.1089C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642634 | p.Asp367Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| rpoA | 3877728 | c.780C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877731 | c.777G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.736_738delTCAinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoA | 3877773 | c.735G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877791 | c.717C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877800 | c.708G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877824 | c.684G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877872 | c.636C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877881 | c.627G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877884 | c.624G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877890 | c.618C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877893 | c.615C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877909 | p.Asn200Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878037 | c.471C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878046 | c.462T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878050 | p.Arg153Lys | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878064 | c.444G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878079 | c.429C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878085 | c.423G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878094 | c.414C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878102 | p.Val136Ile | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878276 | c.232C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878343 | c.165C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878400 | c.108T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878403 | c.105C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878406 | c.102G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878409 | c.99C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878430 | c.78G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878436 | c.72A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878451 | c.57C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878454 | c.54A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878468 | p.Leu14Ile | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878475 | c.33G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3879043 | c.-536C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879070 | c.-563G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986625 | c.-219A>T | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4038266 | c.2439C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038275 | c.2430A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038278 | c.2427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038302 | c.2403C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038308 | c.2397G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038314 | c.2391T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038320 | c.2385G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038338 | c.2367C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038354 | p.Gln784Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038374 | c.2331C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038395 | c.2310C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038463 | p.Ala748Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038485 | p.Gly740Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038488 | c.2217C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038491 | c.2214C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038494 | c.2211G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038509 | p.Asp732Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038512 | c.2193C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038527 | c.2178G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | c.2175G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038533 | p.Arg724Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038536 | c.2169C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038551 | c.2154C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038569 | c.2136C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038647 | c.2058T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038657 | p.Lys683Pro | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038660 | c.2044_2045delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038694 | p.Ser671Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038698 | c.2007C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038821 | c.1884G>A | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038875 | c.1830C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038905 | c.1800A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038920 | c.1785C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039001 | c.1702_1704delAACinsGG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039009 | c.1696C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039031 | c.1674T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4039034 | c.1671C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039037 | c.1668T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039043 | c.1662G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039090 | c.1615C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039166 | c.1539G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | c.1536A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039187 | c.1518G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039243 | c.1462C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039247 | c.1458G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039277 | c.1428C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039283 | c.1422C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039304 | c.1401G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039334 | c.1371G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039343 | c.1362G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039349 | c.1356C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039358 | p.Ser449Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039427 | c.1278G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039454 | c.1251A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039457 | c.1248C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039484 | c.1221T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039574 | p.Ala377Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039601 | c.1104G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039625 | c.1080G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039649 | c.1056G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039673 | c.1032G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039756 | c.949C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039805 | c.900C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039808 | c.897G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039832 | c.873C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039840 | c.865C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039855 | c.850C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039886 | c.819C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.805_807delCTCinsTG | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039907 | c.798G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039913 | c.792C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039943 | c.762G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039988 | c.717C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039994 | p.Glu237Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040009 | p.Ala232Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040020 | c.685C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040051 | c.654C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040090 | c.615T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040144 | c.561G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040234 | c.471C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040240 | c.465C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040252 | c.453C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040257 | p.Ala150Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040270 | c.435C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040306 | c.399G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040314 | c.391C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040318 | c.387C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040324 | c.381G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040333 | c.372G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040336 | c.369G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040351 | c.354C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040528 | c.177G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040540 | c.165G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040567 | c.138C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040600 | c.105A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040654 | c.51G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040681 | c.24T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040695 | c.10C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040696 | c.9A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040699 | c.6C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040711 | c.-7G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040734 | c.-31delT | upstream_gene_variant | 1.0 | pyrazinamide | |
| glpK | 4138643 | c.1113A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138646 | c.1110G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138654 | c.1102C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138655 | c.1101G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138685 | c.1071C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138695 | p.Pro354Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138703 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138714 | p.Ala348Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138721 | c.1035G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138724 | c.1032A>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138727 | c.1029C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138730 | c.1026C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138747 | c.1009C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138751 | c.1005T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240777 | c.915G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240859 | c.997C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240867 | c.1005T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240870 | c.1008T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240875 | p.Ser338Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4240885 | c.1023T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240900 | c.1038A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240903 | c.1041C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240910 | p.Ala350Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4240921 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240936 | c.1074A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240945 | c.1083T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240948 | c.1086G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240954 | c.1092T>C | synonymous_variant | 0.9 | ethambutol | |
| embC | 4240990 | c.1128A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241026 | c.1164C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241030 | c.1168C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241039 | p.Asp393Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241077 | c.1215C>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241080 | c.1218C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241101 | c.1239G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241104 | c.1242G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241125 | c.1263G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241168 | c.1306C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241173 | c.1311C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241182 | c.1320G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241185 | c.1323G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241188 | c.1326C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241453 | c.1591_1593delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4241470 | c.1608C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241479 | c.1617C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241483 | c.1621_1623delGTGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4241486 | c.1624_1626delCTGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4241497 | c.1635G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241500 | c.1638A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241518 | c.1656A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241521 | c.1659T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241528 | c.1666_1668delCGCinsAG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4241536 | c.1674A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241539 | c.1677T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241545 | c.1683T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241548 | c.1686T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248161 | c.1648_1650delCTGinsTA | frameshift_variant&stop_gained | 1.0 | ethambutol | |
| embB | 4248166 | c.1653C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248167 | p.Thr552Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248178 | c.1665C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248199 | c.1686A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248205 | c.1692C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | c.1693_1695delAGCinsGA | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248226 | c.1713G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248241 | c.1728C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248266 | c.1753C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248277 | c.1764G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248301 | c.1788C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248305 | c.1792C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248322 | c.1809G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248334 | c.1821C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248340 | c.1827G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248350 | c.1837T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248355 | c.1842A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248358 | c.1845C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248361 | c.1848A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248362 | p.Ser617Lys | missense_variant | 1.0 | ethambutol | |
| embB | 4249627 | c.3114G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4269012 | c.-176G>C | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269015 | c.819G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4269027 | c.-191C>G | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269033 | c.-197T>C | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269042 | c.-206G>C | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269048 | c.-212C>T | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269051 | c.783C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| ubiA | 4269075 | c.757_759delATTinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| ubiA | 4269088 | p.Ala249Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| ubiA | 4269090 | c.744C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4269096 | c.-260C>A | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269103 | p.Ser244Ala | missense_variant | 1.0 | ethambutol | |
| aftB | 4269114 | c.-278C>T | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269123 | c.-287T>G | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269143 | p.Leu231Val | missense_variant | 1.0 | ethambutol | |
| ubiA | 4269144 | c.690C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| ubiA | 4269164 | p.Leu224Met | missense_variant | 1.0 | ethambutol | |
| aftB | 4269171 | c.-335C>G | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269199 | p.Ser212Thr | missense_variant | 1.0 | ethambutol |
