TB-Profiler result

Run: ERR8976043
Summary

Run ID: ERR8976043

Sample name:

Date: 2024-10-04T16:41:22.899511

Number of reads: 1902266

Percentage reads mapped: 38.42

Median coverage: 50.0

Strain: lineage2.1;lineage2.2;lineage6.3

Spoligotype:

Drug-resistance: HR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage6.3 West-Africa 2 RD702 0.11
lineage3.1.2.2 East-African-Indian RD750 0.05
lineage2.2 East-Asian (Beijing) RD105;RD207 0.64
lineage6.1.3 West-Africa 2 RD702 0.13
lineage2.1 East-Asian (non-Beijing) None 0.17
lineage1.1.1 Indo-Oceanic RD239 0.12
La1.7.1 M.bovis None 0.12
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid katG p.Ala379Val Uncertain significance Mutation from literature
p.Ile335Thr Mutation from literature
p.Ile317Leu Mutation from literature
c.300_301delGC Assoc w R High-level resistance
c.296_297insTG Assoc w R High-level resistance
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Ala388Gly Mutation from literature
p.Asn399Asp Mutation from literature
p.Ala659Thr Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin tlyA c.-2_1delGCGinsCGGA Assoc w R
c.513_514delTT Assoc w R
c.520delGinsCGC Assoc w R
kanamycin
cycloserine
ethionamide ethR p.Ala95Thr Uncertain significance Mutation from literature
clofazimine
para-aminosalicylic_acid
delamanid fbiB c.658delTinsCTG Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance Mutation from literature
tlyA 1917938 c.-2_1delGCGinsCGGA frameshift_variant&synonymous_variant 0.79 capreomycin Assoc w R
tlyA 1918451 c.513_514delTT frameshift_variant 0.47 capreomycin Assoc w R
tlyA 1918459 c.520delGinsCGC frameshift_variant&missense_variant 0.5 capreomycin Assoc w R
katG 2154976 p.Ala379Val missense_variant 0.53 isoniazid Uncertain significance Mutation from literature
katG 2155108 p.Ile335Thr missense_variant 0.79 isoniazid Mutation from literature
katG 2155161 p.Ile317Leu missense_variant 0.7 isoniazid Mutation from literature
katG 2155810 c.300_301delGC frameshift_variant 0.73 isoniazid Assoc w R High-level resistance
katG 2155815 c.296_297insTG frameshift_variant 0.71 isoniazid Assoc w R High-level resistance
fbiB 3642192 c.658delTinsCTG frameshift_variant&missense_variant 0.63 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247448 p.His312Arg missense_variant 0.93 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.83 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.81 ethambutol Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.86 ethambutol Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 0.87 ethambutol Mutation from literature
embB 4248488 p.Ala659Thr missense_variant 0.64 ethambutol Mutation from literature
ethR 4327831 p.Ala95Thr missense_variant 1.0 ethionamide Uncertain significance Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 187 c.187_189delTTAinsCTG synonymous_variant 0.45 isoniazid
dnaA 192 c.192C>A synonymous_variant 0.43 isoniazid
dnaA 204 c.204C>T synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 207 c.207T>C synonymous_variant 0.45 isoniazid
dnaA 210 c.210C>G synonymous_variant 0.45 isoniazid
dnaA 213 c.213A>G synonymous_variant 0.43 isoniazid
dnaA 219 c.219A>G synonymous_variant 0.43 isoniazid
dnaA 225 c.225G>A synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 228 c.228C>G synonymous_variant 0.43 isoniazid
dnaA 231 c.231T>C synonymous_variant 0.43 isoniazid
dnaA 237 c.237G>C synonymous_variant 0.43 isoniazid
dnaA 246 c.246T>C synonymous_variant 0.43 isoniazid
dnaA 255 c.255T>G synonymous_variant 0.45 isoniazid
dnaA 504 c.504T>C synonymous_variant 0.74 isoniazid
dnaA 510 c.510T>C synonymous_variant 0.76 isoniazid
dnaA 522 c.522T>C synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 0.8 isoniazid
dnaA 534 c.534T>G synonymous_variant 0.81 isoniazid
dnaA 540 c.540C>G synonymous_variant 0.84 isoniazid
dnaA 543 c.543C>G synonymous_variant 0.87 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.86 isoniazid
dnaA 576 c.576G>C synonymous_variant 0.89 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 591 c.591C>G synonymous_variant 0.89 isoniazid
dnaA 600 c.600T>C synonymous_variant 0.94 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.92 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.92 isoniazid
dnaA 636 c.636C>G synonymous_variant 0.94 isoniazid
dnaA 645 c.645A>G synonymous_variant 0.94 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.93 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.91 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.92 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.92 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.91 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.91 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.91 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.92 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.92 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.91 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.92 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.91 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.91 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.91 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.91 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.91 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.91 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.91 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.91 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.91 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 0.91 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.91 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.88 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.86 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.85 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.85 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.86 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.85 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.85 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.82 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.79 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.78 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.83 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.85 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.85 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.87 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.84 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.83 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 1002 c.1002G>A synonymous_variant 0.82 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 0.84 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.85 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.86 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.84 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.82 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.81 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 0.8 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.79 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.78 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.8 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.8 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.79 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.78 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.79 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.81 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.81 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.81 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 0.81 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.82 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.84 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.87 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.87 isoniazid
dnaA 1204 c.1204C>T synonymous_variant 0.87 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.9 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.89 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.89 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.89 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.89 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.88 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.86 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.86 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.86 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.88 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.89 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.87 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 0.85 isoniazid
dnaA 1332 c.1332A>T synonymous_variant 0.84 isoniazid
dnaA 1335 c.1335G>A synonymous_variant 0.85 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 0.85 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.87 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.84 isoniazid Not assoc w R - Interim
dnaA 1365 c.1365C>G synonymous_variant 0.84 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.85 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.84 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.85 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.86 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.85 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.85 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.86 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.85 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.86 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.86 isoniazid
dnaA 1419 c.1419C>G synonymous_variant 0.86 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.88 isoniazid
dnaA 1461 c.1461C>A synonymous_variant 0.78 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.78 isoniazid
dnaA 1470 c.1470C>G synonymous_variant 0.78 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 1485 c.1485A>G synonymous_variant 0.74 isoniazid
dnaA 1488 c.1488A>G synonymous_variant 0.71 isoniazid
dnaA 1503 c.1503C>T synonymous_variant 0.61 isoniazid
gyrB 5788 c.549G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrB 5791 c.552A>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrB 5806 c.567C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrB 5809 c.570C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrB 5815 c.576C>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 5824 c.585A>G synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrB 5827 c.588G>A synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 5848 c.609G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrB 5863 c.624G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrB 5873 c.634A>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrB 5882 p.Gln215Asn missense_variant 0.54 levofloxacin
moxifloxacin
gyrB 5887 p.Asp216Glu missense_variant 0.54 levofloxacin
moxifloxacin
gyrB 5902 c.663A>G synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrB 6079 c.840C>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 0.79 levofloxacin
moxifloxacin
gyrB 6091 c.852G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 0.86 levofloxacin
moxifloxacin
gyrB 6127 c.888G>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6136 c.897G>A synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6169 c.930C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6217 c.978G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrB 6274 c.1035C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6299 c.1060C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6325 c.-977C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6427 c.-875T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrB 6440 p.Thr401Ala missense_variant 0.84 levofloxacin
moxifloxacin
gyrA 6448 c.-854G>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrB 6455 p.Val406Ile missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 6460 c.-842G>C upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6469 c.-833T>G upstream_gene_variant 0.52 levofloxacin
moxifloxacin
gyrA 6586 c.-716T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6598 c.-704C>G upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6602 c.-700C>T upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>G upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>G upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.78 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6742 c.-560A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.92 levofloxacin
moxifloxacin
gyrB 6824 c.1585C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6878 c.1639T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.91 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.91 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6931 c.-371A>C upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 0.89 levofloxacin
moxifloxacin
gyrB 6937 c.1698G>A synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6955 c.-347G>A upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.87 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6973 c.-329G>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>G upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7018 c.-284G>C upstream_gene_variant 0.84 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.83 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 0.83 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7108 c.-194G>A upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 7114 c.-188C>A upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrB 7124 p.Ser629Thr missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.81 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.82 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.7 levofloxacin
moxifloxacin
gyrA 7237 c.-65C>T upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 7243 c.-59G>A upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7538 c.237G>A synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7626 c.325C>T synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7646 c.345C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7649 c.348C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7731 p.Glu144Gln missense_variant 0.94 levofloxacin Uncertain significance
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7799 c.498A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7838 c.537C>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 7884 p.Arg195Gly missense_variant 0.9 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7892 c.591G>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 0.86 levofloxacin
moxifloxacin
gyrA 7942 p.Glu214Ala missense_variant 0.84 levofloxacin
moxifloxacin
gyrA 7955 c.654G>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7958 c.657C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 7970 c.669T>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 7976 c.675C>A synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7991 c.690C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7992 p.Ala231Ser missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 7997 c.696A>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8009 c.708A>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8010 p.Ser237Thr missense_variant 0.82 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 0.85 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8054 c.753T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.96 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.95 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8351 c.1050C>T synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.89 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8498 c.1197C>T synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Gln missense_variant 0.92 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8562 c.1261C>T synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8726 c.1425G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8735 c.1434C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8747 c.1446A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8918 c.1617C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8951 c.1650G>A synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>C synonymous_variant 0.87 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.86 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9119 c.1818A>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9134 c.1833C>G synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.78 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.77 levofloxacin
moxifloxacin
gyrA 9152 c.1851C>T synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.75 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9204 p.Ser635Thr missense_variant 0.8 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.84 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9275 c.1974G>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9281 c.1980C>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.87 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9413 c.2112G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9419 c.2118T>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Ala missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 9429 p.Arg710Tyr missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 9443 c.2142G>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9449 c.2148C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9452 c.2151G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9455 c.2154T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9458 c.2157A>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9467 c.2166T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9485 c.2184A>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9488 c.2187G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9491 c.2190C>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9494 c.2193T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9497 c.2196G>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9500 c.2199A>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9503 c.2202T>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9518 c.2217A>G synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 9521 c.2220C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9545 c.2244A>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 9548 c.2247T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9557 c.2256G>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9560 c.2259C>G synonymous_variant 0.72 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9566 c.2265C>T synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9575 c.2274G>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9578 c.2277C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9585 c.2284T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9590 c.2289T>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9593 c.2292G>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9597 c.2296T>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9605 c.2304C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9611 p.Asp770Glu missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 9626 c.2325T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9629 c.2328C>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9630 p.Val777Ile missense_variant 0.76 levofloxacin
moxifloxacin
gyrA 9635 c.2334T>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9647 c.2346C>T synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9665 c.2364A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9666 p.Arg789Gly missense_variant 0.78 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9674 c.2373T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9677 c.2376C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9704 c.2403T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9708 c.2407T>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9722 c.2421C>T synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9734 c.2433A>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 9738 c.2437T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 9749 c.2448G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
fgd1 490549 c.-234T>C upstream_gene_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 490555 c.-228G>T upstream_gene_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 490559 c.-224G>C upstream_gene_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 490573 c.-210T>C upstream_gene_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 490577 c.-206T>C upstream_gene_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 490581 c.-202_-201delACinsGT upstream_gene_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 490597 c.-186G>C upstream_gene_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 490598 c.-185G>C upstream_gene_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 490601 c.-182G>C upstream_gene_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 490604 c.-179A>G upstream_gene_variant 0.42 pretomanid
delamanid
clofazimine
fgd1 490613 c.-170A>C upstream_gene_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 490617 c.-166_-165delTTinsGC upstream_gene_variant 0.4 pretomanid
delamanid
clofazimine
fgd1 490627 c.-156T>C upstream_gene_variant 0.35 pretomanid
delamanid
clofazimine
fgd1 490634 c.-149A>T upstream_gene_variant 0.33 pretomanid
delamanid
clofazimine
fgd1 490794 c.12G>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 490797 c.15G>A synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fgd1 490800 c.18A>C synonymous_variant 0.58 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 490803 c.21T>A synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 490812 c.30A>G synonymous_variant 0.71 pretomanid
delamanid
clofazimine
fgd1 490815 c.33G>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 490827 c.45C>T synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 490833 c.51G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 490842 c.60C>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 490851 c.69A>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 490902 c.120T>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490905 c.123T>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490911 c.129T>G synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 490917 c.135C>A synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 490921 p.Gln47Glu missense_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490932 c.150T>C synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 490948 p.Ser56Ala missense_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 490962 c.180T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 490968 c.186C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491010 c.228C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fgd1 491031 c.249C>G synonymous_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 491038 p.Ile86Val missense_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 0.82 pretomanid
delamanid
clofazimine
fgd1 491077 p.Asn99Gly missense_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>G synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fgd1 491094 c.312C>G synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 0.85 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fgd1 491137 p.Glu119Gln missense_variant 0.86 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.87 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fgd1 491250 c.468G>A synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.91 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 0.88 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.88 pretomanid
delamanid
clofazimine
fgd1 491319 c.537G>C synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fgd1 491331 c.549G>A synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fgd1 491343 c.561C>G synonymous_variant 0.81 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>C synonymous_variant 0.82 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491359 p.Ile193Val missense_variant 0.76 pretomanid
delamanid
clofazimine
fgd1 491364 c.582T>C synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fgd1 491367 c.585G>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491388 c.606C>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491453 p.Gly224Asp missense_variant 0.46 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fgd1 491472 c.690A>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fgd1 491502 c.720G>A synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>G synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fgd1 491509 c.727T>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 0.73 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491550 c.768T>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491583 c.801G>A synonymous_variant 0.78 pretomanid
delamanid
clofazimine
fgd1 491595 c.813C>G synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>C synonymous_variant 0.73 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491742 c.960T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R
mshA 574520 c.-828T>C upstream_gene_variant 0.5 isoniazid
ethionamide
mshA 574529 c.-819T>C upstream_gene_variant 0.57 isoniazid
ethionamide
mshA 574532 c.-816T>G upstream_gene_variant 0.57 isoniazid
ethionamide
mshA 574535 c.-813C>G upstream_gene_variant 0.57 isoniazid
ethionamide
mshA 574541 c.-807T>C upstream_gene_variant 0.59 isoniazid
ethionamide
mshA 574550 c.-798C>G upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574553 c.-795T>C upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574559 c.-789T>G upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574565 c.-783T>G upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574574 c.-774A>C upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574576 c.-772_-771delCCinsAG upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 574586 c.-762G>C upstream_gene_variant 0.58 isoniazid
ethionamide
mshA 574589 c.-759T>C upstream_gene_variant 0.58 isoniazid
ethionamide
mshA 574592 c.-756C>G upstream_gene_variant 0.61 isoniazid
ethionamide
mshA 574595 c.-753A>G upstream_gene_variant 0.65 isoniazid
ethionamide
mshA 574616 c.-732G>C upstream_gene_variant 0.73 isoniazid
ethionamide
mshA 574625 c.-723C>G upstream_gene_variant 0.71 isoniazid
ethionamide
mshA 574650 c.-698A>C upstream_gene_variant 0.76 isoniazid
ethionamide
mshA 574655 c.-693C>G upstream_gene_variant 0.76 isoniazid
ethionamide
mshA 574664 c.-684G>C upstream_gene_variant 0.71 isoniazid
ethionamide
mshA 574671 c.-677_-675delGCAinsCTG upstream_gene_variant 0.59 isoniazid
ethionamide
mshA 574676 c.-672G>C upstream_gene_variant 0.56 isoniazid
ethionamide
mshA 574683 c.-665T>C upstream_gene_variant 0.56 isoniazid Uncertain significance
ethionamide
mshA 574688 c.-660G>C upstream_gene_variant 0.56 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.6 isoniazid
ethionamide
mshA 574700 c.-648C>G upstream_gene_variant 0.65 isoniazid
ethionamide
mshA 574712 c.-636A>G upstream_gene_variant 0.67 isoniazid
ethionamide
mshA 574718 c.-630A>C upstream_gene_variant 0.67 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 574731 c.-617A>G upstream_gene_variant 0.71 isoniazid
ethionamide
mshA 574739 c.-609T>C upstream_gene_variant 0.71 isoniazid
ethionamide
mshA 574996 c.-352C>G upstream_gene_variant 0.55 isoniazid
ethionamide
mshA 575006 c.-342C>G upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 575009 c.-339T>C upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 575011 c.-337G>A upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 575018 c.-330C>G upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 575030 c.-318T>C upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 575034 c.-314_-312delTTAinsATG upstream_gene_variant 0.62 isoniazid
ethionamide
mshA 575042 c.-306T>C upstream_gene_variant 0.66 isoniazid
ethionamide
mshA 575051 c.-297A>G upstream_gene_variant 0.68 isoniazid Uncertain significance
ethionamide Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 0.68 isoniazid
ethionamide
mshA 575060 c.-288G>C upstream_gene_variant 0.7 isoniazid
ethionamide
mshA 575063 c.-285T>C upstream_gene_variant 0.72 isoniazid
ethionamide
mshA 575066 c.-282C>G upstream_gene_variant 0.72 isoniazid
ethionamide
mshA 575072 c.-276G>C upstream_gene_variant 0.72 isoniazid
ethionamide
mshA 575075 c.-273T>C upstream_gene_variant 0.72 isoniazid Uncertain significance
ethionamide
mshA 575081 c.-267A>G upstream_gene_variant 0.72 isoniazid
ethionamide
mshA 575084 c.-264T>C upstream_gene_variant 0.72 isoniazid
ethionamide
mshA 575117 c.-231T>C upstream_gene_variant 0.73 isoniazid
ethionamide
mshA 575118 c.-230A>G upstream_gene_variant 0.73 isoniazid Uncertain significance
ethionamide
mshA 575123 c.-225A>G upstream_gene_variant 0.71 isoniazid
ethionamide
mshA 575124 c.-224_-222delGGGinsCGC upstream_gene_variant 0.71 isoniazid
ethionamide
mshA 575137 c.-211C>G upstream_gene_variant 0.68 isoniazid
ethionamide
mshA 575488 c.141T>G synonymous_variant 0.56 isoniazid
ethionamide
mshA 575491 c.144G>C synonymous_variant 0.53 isoniazid
ethionamide
mshA 575492 p.Leu49Val missense_variant 0.53 isoniazid
ethionamide
mshA 575503 c.156G>C synonymous_variant 0.48 isoniazid
ethionamide
mshA 575512 c.165A>G synonymous_variant 0.5 isoniazid
ethionamide
mshA 575515 c.168G>A synonymous_variant 0.59 isoniazid
ethionamide
mshA 575521 c.174A>C synonymous_variant 0.65 isoniazid
ethionamide
mshA 575527 c.180G>C synonymous_variant 0.7 isoniazid
ethionamide
mshA 575536 c.189T>C synonymous_variant 0.77 isoniazid
ethionamide
mshA 575542 c.195C>G synonymous_variant 0.81 isoniazid
ethionamide
mshA 575554 c.207C>T synonymous_variant 0.82 isoniazid
ethionamide
mshA 575561 p.Met72Val missense_variant 0.83 isoniazid
ethionamide
mshA 575569 c.222A>G synonymous_variant 0.83 isoniazid
ethionamide
mshA 575571 p.Ser75Thr missense_variant 0.83 isoniazid
ethionamide
mshA 575575 c.228G>C synonymous_variant 0.84 isoniazid
ethionamide
mshA 575587 c.240C>A synonymous_variant 0.87 isoniazid
ethionamide
mshA 575590 c.243T>C synonymous_variant 0.87 isoniazid
ethionamide
mshA 575593 c.246G>C synonymous_variant 0.89 isoniazid
ethionamide
mshA 575623 c.276C>G synonymous_variant 0.91 isoniazid
ethionamide
mshA 575629 c.282A>C synonymous_variant 0.89 isoniazid
ethionamide
mshA 575635 c.288A>C synonymous_variant 0.88 isoniazid Not assoc w R - Interim
ethionamide
mshA 575638 c.291T>C synonymous_variant 0.88 isoniazid
ethionamide
mshA 575641 c.294A>G synonymous_variant 0.88 isoniazid
ethionamide
mshA 575648 p.Val101Gln missense_variant 0.94 isoniazid
ethionamide
mshA 575659 c.312A>G synonymous_variant 0.92 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 0.92 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.91 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.91 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 0.92 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.94 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.92 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 0.93 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.91 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.88 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.91 isoniazid
ethionamide
mshA 575752 c.405G>A synonymous_variant 0.9 isoniazid Not assoc w R - Interim
ethionamide
mshA 575767 c.420G>A synonymous_variant 0.91 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 0.9 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.91 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.89 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 0.9 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.88 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.84 isoniazid
ethionamide
mshA 575884 c.537G>C synonymous_variant 0.8 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 0.79 isoniazid
ethionamide
mshA 575902 c.555C>T synonymous_variant 0.73 isoniazid Not assoc w R - Interim
ethionamide
mshA 575905 c.558G>C synonymous_variant 0.73 isoniazid
ethionamide
mshA 575914 c.567C>G synonymous_variant 0.76 isoniazid
ethionamide
mshA 575915 p.Asp190Gln missense_variant 0.76 isoniazid
ethionamide
mshA 575920 c.573C>G synonymous_variant 0.8 isoniazid
ethionamide
mshA 575923 p.Gly193Ser missense_variant 0.8 isoniazid
ethionamide
mshA 575929 c.582C>A synonymous_variant 0.76 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 0.76 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 0.76 isoniazid
ethionamide
mshA 575953 c.606G>C synonymous_variant 0.76 isoniazid
ethionamide
mshA 575965 c.618C>G synonymous_variant 0.74 isoniazid Not assoc w R - Interim
ethionamide
mshA 575977 c.630G>C synonymous_variant 0.74 isoniazid
ethionamide
mshA 575980 c.633T>C synonymous_variant 0.74 isoniazid
ethionamide
mshA 575984 c.637T>C synonymous_variant 0.74 isoniazid
ethionamide
mshA 576163 c.816A>C synonymous_variant 0.85 isoniazid
ethionamide
mshA 576184 c.837A>C synonymous_variant 0.72 isoniazid
ethionamide
mshA 576193 c.846T>C synonymous_variant 0.74 isoniazid
ethionamide
mshA 576197 c.850C>T synonymous_variant 0.74 isoniazid
ethionamide
mshA 576205 c.858G>C synonymous_variant 0.7 isoniazid Not assoc w R - Interim
ethionamide
mshA 576211 c.864C>G synonymous_variant 0.7 isoniazid
ethionamide
mshA 576214 c.867G>A synonymous_variant 0.7 isoniazid
ethionamide
mshA 576215 c.868T>C synonymous_variant 0.7 isoniazid
ethionamide
mshA 576233 p.Ile296Val missense_variant 0.7 isoniazid
ethionamide
mshA 576247 c.900A>G synonymous_variant 0.67 isoniazid
ethionamide
mshA 576258 p.Ser304Thr missense_variant 0.64 isoniazid
ethionamide
mshA 576262 c.915T>C synonymous_variant 0.64 isoniazid
ethionamide
mshA 576268 c.921T>C synonymous_variant 0.61 isoniazid
ethionamide
mshA 576271 c.924A>G synonymous_variant 0.61 isoniazid
ethionamide
mshA 576281 c.934C>T synonymous_variant 0.61 isoniazid Not assoc w R - Interim
ethionamide
mshA 576285 p.Val313Ala missense_variant 0.58 isoniazid
ethionamide
mshA 576292 c.945C>G synonymous_variant 0.58 isoniazid
ethionamide
mshA 576304 c.957G>C synonymous_variant 0.44 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 619531 c.-360T>G upstream_gene_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 619535 c.-356_-355delCAinsGC upstream_gene_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 619552 c.-339A>G upstream_gene_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 619555 c.-336C>G upstream_gene_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 619558 c.-333G>C upstream_gene_variant 0.83 kanamycin
capreomycin
amikacin
ccsA 619564 c.-327C>G upstream_gene_variant 0.84 kanamycin
capreomycin
amikacin
ccsA 619570 c.-321G>C upstream_gene_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 619574 c.-317G>A upstream_gene_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 0.87 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 619627 c.-264C>G upstream_gene_variant 0.82 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>A upstream_gene_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 619648 c.-243C>G upstream_gene_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 619654 c.-237A>C upstream_gene_variant 0.85 kanamycin
capreomycin
amikacin
ccsA 619655 c.-236A>G upstream_gene_variant 0.87 kanamycin
capreomycin
amikacin
ccsA 619669 c.-222G>C upstream_gene_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 619672 c.-219A>C upstream_gene_variant 0.79 kanamycin
capreomycin
amikacin
ccsA 619697 c.-194_-192delAGGinsCGC upstream_gene_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620169 c.279G>C synonymous_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 620173 p.Val95Leu missense_variant 0.56 kanamycin
capreomycin
amikacin
ccsA 620198 p.Gln103Leu missense_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620257 p.Ile123Val missense_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620265 c.375C>G synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620269 p.Val127Ile missense_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>C synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620322 c.432G>C synonymous_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.93 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.95 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.92 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>C synonymous_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620461 p.Val191Ile missense_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620481 c.591T>G synonymous_variant 0.71 kanamycin
capreomycin
amikacin
ccsA 620482 p.Val198Leu missense_variant 0.7 kanamycin
capreomycin
amikacin
ccsA 620490 c.600A>C synonymous_variant 0.62 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620495 p.Arg202Pro missense_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620589 c.699G>C synonymous_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>T synonymous_variant 0.53 kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
ccsA 620607 c.717T>G synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620619 c.729G>C synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620622 c.732G>C synonymous_variant 0.65 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 0.76 kanamycin
capreomycin
amikacin
ccsA 620646 c.756G>A synonymous_variant 0.87 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 0.94 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.91 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.9 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620745 c.855G>C synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>A synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 0.89 kanamycin
capreomycin
amikacin
ccsA 620784 c.894C>G synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>G synonymous_variant 0.88 kanamycin
capreomycin
amikacin
ccsA 620809 c.919C>T synonymous_variant 0.81 kanamycin
capreomycin
amikacin
ccsA 620829 c.939G>C synonymous_variant 0.68 kanamycin
capreomycin
amikacin
ccsA 620835 c.945C>G synonymous_variant 0.5 kanamycin
capreomycin
amikacin
Rv0565c 656383 p.Val363Asn missense_variant 0.4 ethionamide
Rv0565c 656391 c.1080C>G synonymous_variant 0.43 ethionamide
Rv0565c 656402 p.Ala357Thr missense_variant 0.43 ethionamide
Rv0565c 656409 c.1062C>T synonymous_variant 0.43 ethionamide
Rv0565c 656412 c.1059T>C synonymous_variant 0.4 ethionamide
Rv0565c 656415 c.1056G>C synonymous_variant 0.4 ethionamide
Rv0565c 656418 c.1053A>G synonymous_variant 0.4 ethionamide
Rv0565c 656424 c.1047G>A synonymous_variant 0.43 ethionamide
Rv0565c 656444 p.Val343Ile missense_variant 0.43 ethionamide Uncertain significance
Rv0565c 656808 c.663A>G synonymous_variant 0.44 ethionamide
Rv0565c 656814 c.657A>G synonymous_variant 0.59 ethionamide
Rv0565c 656826 c.645C>T synonymous_variant 0.67 ethionamide
Rv0565c 656832 c.639G>C synonymous_variant 0.67 ethionamide
Rv0565c 656835 c.636C>G synonymous_variant 0.7 ethionamide
Rv0565c 656838 c.633A>C synonymous_variant 0.7 ethionamide
Rv0565c 656841 c.630G>A synonymous_variant 0.7 ethionamide Not assoc w R - Interim
Rv0565c 656853 c.618A>G synonymous_variant 0.7 ethionamide
Rv0565c 656859 p.Glu204Ala missense_variant 0.73 ethionamide
Rv0565c 656865 c.606G>C synonymous_variant 0.7 ethionamide
Rv0565c 656872 p.Thr200Ser missense_variant 0.71 ethionamide
Rv0565c 656880 c.591C>G synonymous_variant 0.71 ethionamide
Rv0565c 656883 p.Ile196Leu missense_variant 0.71 ethionamide Uncertain significance
Rv0565c 656889 c.582A>G synonymous_variant 0.79 ethionamide
Rv0565c 656901 c.570C>G synonymous_variant 0.82 ethionamide
Rv0565c 656922 p.Ile183Val missense_variant 0.8 ethionamide
Rv0565c 656934 c.537C>G synonymous_variant 0.82 ethionamide
Rv0565c 656943 c.528G>C synonymous_variant 0.83 ethionamide
Rv0565c 656946 c.525T>C synonymous_variant 0.8 ethionamide
Rv0565c 656952 c.519A>C synonymous_variant 0.8 ethionamide Not assoc w R - Interim
Rv0565c 656967 c.504T>C synonymous_variant 0.7 ethionamide
Rv0565c 656973 c.498A>G synonymous_variant 0.68 ethionamide
Rv0565c 656976 p.Ala165Thr missense_variant 0.69 ethionamide
Rv0565c 656983 p.Gly163Thr missense_variant 0.68 ethionamide
Rv0565c 656985 c.486T>C synonymous_variant 0.68 ethionamide
Rv0565c 656990 p.Lys161Glu missense_variant 0.68 ethionamide
Rv0565c 657000 p.Gly157Pro missense_variant 0.68 ethionamide
Rv0565c 657027 c.444T>C synonymous_variant 0.62 ethionamide
Rv0565c 657142 p.Arg110His missense_variant 0.44 ethionamide Uncertain significance
Rv0565c 657144 c.327T>G synonymous_variant 0.59 ethionamide
Rv0565c 657160 p.Glu104Arg missense_variant 0.71 ethionamide
Rv0565c 657171 c.300T>C synonymous_variant 0.8 ethionamide
Rv0565c 657189 c.282C>G synonymous_variant 0.83 ethionamide
Rv0565c 657192 p.Met93Thr missense_variant 0.83 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.83 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.85 ethionamide
Rv0565c 657222 c.249C>G synonymous_variant 0.86 ethionamide
Rv0565c 657231 p.Ile80Val missense_variant 0.84 ethionamide
Rv0565c 657237 c.234A>G synonymous_variant 0.85 ethionamide
Rv0565c 657242 p.Glu77Lys missense_variant 0.87 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.85 ethionamide
Rv0565c 657261 c.210C>G synonymous_variant 0.86 ethionamide
Rv0565c 657264 c.207T>C synonymous_variant 0.86 ethionamide
Rv0565c 657267 c.204G>C synonymous_variant 0.86 ethionamide
Rv0565c 657291 c.180C>G synonymous_variant 0.87 ethionamide
Rv0565c 657300 c.171C>T synonymous_variant 0.86 ethionamide
Rv0565c 657303 c.168C>G synonymous_variant 0.87 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.84 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.82 ethionamide
Rv0565c 657327 c.144C>G synonymous_variant 0.82 ethionamide
Rv0565c 657347 c.124A>C synonymous_variant 0.82 ethionamide
Rv0565c 657348 c.123A>G synonymous_variant 0.83 ethionamide
Rv0565c 657357 p.Thr38Ala missense_variant 0.81 ethionamide
Rv0565c 657364 p.Thr36Ser missense_variant 0.75 ethionamide
Rv0565c 657375 c.96C>T synonymous_variant 0.72 ethionamide
Rv0565c 657381 c.90A>G synonymous_variant 0.74 ethionamide
Rv0565c 657385 p.Ile29Thr missense_variant 0.71 ethionamide
Rv0565c 657403 p.Gly23Asp missense_variant 0.71 ethionamide
Rv0565c 657405 p.Leu22Ile missense_variant 0.72 ethionamide
Rv0565c 657408 c.63A>C synonymous_variant 0.72 ethionamide
Rv0565c 657417 c.54C>G synonymous_variant 0.72 ethionamide
Rv0565c 657432 p.Val13Leu missense_variant 0.57 ethionamide
Rv0565c 657560 c.-90G>C upstream_gene_variant 0.59 ethionamide
Rv0565c 657563 c.-93T>C upstream_gene_variant 0.61 ethionamide
Rv0565c 657571 c.-101T>C upstream_gene_variant 0.62 ethionamide
Rv0565c 657572 c.-102A>G upstream_gene_variant 0.62 ethionamide
Rv0565c 657578 c.-108T>C upstream_gene_variant 0.75 ethionamide
Rv0565c 657592 c.-122A>C upstream_gene_variant 0.84 ethionamide
Rv0565c 657596 c.-126G>C upstream_gene_variant 0.88 ethionamide
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.89 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.9 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.89 ethionamide
Rv0565c 657641 c.-171C>G upstream_gene_variant 0.91 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.92 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.94 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.95 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657719 c.-249C>G upstream_gene_variant 0.97 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.98 ethionamide
hadA 731681 c.-249A>C upstream_gene_variant 0.66 isoniazid
hadA 731687 c.-243_-242insCACGGATTTTTT upstream_gene_variant 0.64 isoniazid
hadA 731690 c.-240A>C upstream_gene_variant 0.64 isoniazid
hadA 731693 c.-237C>A upstream_gene_variant 0.64 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.6 isoniazid
hadA 731701 c.-229A>G upstream_gene_variant 0.58 isoniazid
hadA 731702 c.-228G>C upstream_gene_variant 0.58 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 0.56 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.56 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.58 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.74 isoniazid
hadA 731741 c.-189G>A upstream_gene_variant 0.74 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.73 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.71 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.62 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.54 isoniazid
hadA 731792 c.-138G>A upstream_gene_variant 0.54 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.5 isoniazid
hadA 731816 c.-114G>A upstream_gene_variant 0.47 isoniazid
hadA 731833 c.-97T>A upstream_gene_variant 0.52 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 0.5 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.5 isoniazid
hadA 731849 c.-81C>T upstream_gene_variant 0.54 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.56 isoniazid
hadA 732238 c.309G>C synonymous_variant 0.55 isoniazid
hadA 732253 c.324T>C synonymous_variant 0.69 isoniazid
hadA 732259 c.330T>C synonymous_variant 0.71 isoniazid
hadA 732268 c.339T>G synonymous_variant 0.73 isoniazid
hadA 732270 p.Glu114Val missense_variant 0.74 isoniazid
hadA 732272 p.Ala115Ser missense_variant 0.76 isoniazid
hadA 732295 c.366G>C synonymous_variant 0.83 isoniazid
hadA 732304 c.375C>T synonymous_variant 0.85 isoniazid
hadA 732305 p.Ile126Val missense_variant 0.86 isoniazid
hadA 732308 p.Val127Ile missense_variant 0.85 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.86 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.89 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.9 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.92 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.92 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.91 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.9 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.89 isoniazid
nusG 734078 c.-176C>A upstream_gene_variant 0.58 rifampicin
nusG 734093 c.-161A>C upstream_gene_variant 0.54 rifampicin
nusG 734102 c.-152G>C upstream_gene_variant 0.52 rifampicin
nusG 734111 c.-143A>G upstream_gene_variant 0.5 rifampicin
nusG 734114 c.-140A>G upstream_gene_variant 0.5 rifampicin
nusG 734120 c.-134T>C upstream_gene_variant 0.52 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.52 rifampicin
nusG 734132 c.-122G>C upstream_gene_variant 0.52 rifampicin
nusG 734135 c.-119G>C upstream_gene_variant 0.52 rifampicin
nusG 734144 c.-110G>C upstream_gene_variant 0.58 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.57 rifampicin
nusG 734173 c.-81C>G upstream_gene_variant 0.68 rifampicin
nusG 734175 c.-79_-77delGGTinsCTG upstream_gene_variant 0.68 rifampicin
nusG 734180 c.-74T>G upstream_gene_variant 0.68 rifampicin Uncertain significance
nusG 734183 c.-71C>T upstream_gene_variant 0.7 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.68 rifampicin Uncertain significance
nusG 734205 c.-49A>C upstream_gene_variant 0.62 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.62 rifampicin
nusG 734223 c.-30_-28delGCT upstream_gene_variant 0.55 rifampicin
nusG 734230 c.-24_-23insTGACGCCGCTTTGAA upstream_gene_variant 0.54 rifampicin
nusG 734247 c.-7_-6delGAinsC upstream_gene_variant 0.57 rifampicin
nusG 734251 c.-3A>C upstream_gene_variant 0.57 rifampicin
nusG 734275 p.Thr8Pro missense_variant 0.58 rifampicin
nusG 734340 c.87T>G synonymous_variant 0.44 rifampicin
nusG 734352 c.99T>C synonymous_variant 0.68 rifampicin
nusG 734370 c.117A>G synonymous_variant 0.78 rifampicin
nusG 734373 c.120G>C synonymous_variant 0.78 rifampicin
nusG 734376 c.123G>A synonymous_variant 0.79 rifampicin
nusG 734407 p.Val52Ile missense_variant 0.87 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.88 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.9 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.92 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.93 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.92 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>G synonymous_variant 0.93 rifampicin
nusG 734499 c.246G>C synonymous_variant 0.95 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.93 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
nusG 734595 c.342C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 0.88 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.88 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.9 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.87 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.86 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.84 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
nusG 734658 c.405A>G synonymous_variant 0.84 rifampicin Not assoc w R
nusG 734661 c.408A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
nusG 734664 c.411T>G synonymous_variant 0.83 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.84 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734680 p.Ala143Ser missense_variant 0.83 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.84 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.81 rifampicin
nusG 734715 c.462G>C synonymous_variant 0.8 rifampicin
nusG 734718 c.465G>C synonymous_variant 0.8 rifampicin
nusG 734719 p.Ser156Ala missense_variant 0.8 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.82 rifampicin
nusG 734732 p.Ala160Val missense_variant 0.82 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.91 rifampicin
nusG 734757 c.504T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734778 c.525G>C synonymous_variant 0.92 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.93 rifampicin
nusG 734792 p.Val180Ala missense_variant 0.93 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.93 rifampicin Uncertain significance
nusG 734820 c.567A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 0.94 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.94 rifampicin
nusG 734841 c.588G>A synonymous_variant 0.94 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.93 rifampicin
nusG 734853 c.600A>C synonymous_variant 0.93 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.93 rifampicin
nusG 734865 c.612G>C synonymous_variant 0.93 rifampicin
nusG 734882 p.Ala210Gly missense_variant 0.9 rifampicin
nusG 734886 c.633A>G synonymous_variant 0.9 rifampicin
nusG 734895 c.642A>G synonymous_variant 0.88 rifampicin
nusG 734910 c.657C>G synonymous_variant 0.83 rifampicin
nusG 734931 c.678A>G synonymous_variant 0.67 rifampicin
nusG 734940 c.687G>A synonymous_variant 0.65 rifampicin
rpoB 759606 c.-201T>C upstream_gene_variant 0.54 rifampicin
rpoB 759644 c.-163T>A upstream_gene_variant 0.62 rifampicin
rpoB 759647 c.-160T>C upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoB 759656 c.-151_-150delAGinsC upstream_gene_variant 0.6 rifampicin
rpoB 759662 c.-145C>T upstream_gene_variant 0.62 rifampicin
rpoB 759667 c.-140C>T upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoB 759670 c.-137C>T upstream_gene_variant 0.62 rifampicin Uncertain significance
rpoB 759671 c.-136G>T upstream_gene_variant 0.62 rifampicin
rpoB 759672 c.-135G>C upstream_gene_variant 0.62 rifampicin
rpoB 759683 c.-124T>C upstream_gene_variant 0.64 rifampicin
rpoB 759701 c.-106A>T upstream_gene_variant 0.64 rifampicin
rpoB 759707 c.-100C>T upstream_gene_variant 0.62 rifampicin
rpoB 759715 c.-91delA upstream_gene_variant 0.57 rifampicin
rpoB 759725 c.-82A>C upstream_gene_variant 0.44 rifampicin
rpoB 759728 c.-78_-77delTA upstream_gene_variant 0.41 rifampicin
rpoB 760059 p.Tyr85Asp missense_variant 0.72 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.75 rifampicin
rpoB 760088 c.282C>G synonymous_variant 0.82 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>T synonymous_variant 0.86 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.87 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.89 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.91 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.93 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.93 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.93 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.93 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.91 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.93 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.96 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.96 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760514 c.708C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.95 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.96 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.98 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.96 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>G synonymous_variant 0.96 rifampicin
rpoB 760721 c.915C>G synonymous_variant 0.96 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.94 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.94 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.94 rifampicin
rpoB 760763 c.957C>T synonymous_variant 0.94 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.94 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.93 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.93 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.94 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.98 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.98 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.97 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.93 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.94 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.94 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.94 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.94 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.94 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.94 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.94 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.94 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.93 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.94 rifampicin
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.93 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.92 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.91 rifampicin
rpoB 761189 c.1383T>G synonymous_variant 0.92 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 0.94 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761360 c.1554T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.88 rifampicin
rpoB 761373 p.Val523His missense_variant 0.87 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.86 rifampicin
rpoB 761434 c.1629_1630delTG frameshift_variant 0.85 rifampicin
rpoB 761440 c.1634_1635delACinsCAAG frameshift_variant&missense_variant 0.85 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.85 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.84 rifampicin
rpoB 761452 p.Val549Ala missense_variant 0.84 rifampicin
rpoB 761457 p.Pro551Ala missense_variant 0.84 rifampicin
rpoB 761462 c.1656C>G synonymous_variant 0.87 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.91 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.91 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.9 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.94 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.93 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.93 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.94 rifampicin
rpoB 761723 c.1917_1919delAGAinsG frameshift_variant&synonymous_variant 0.91 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.91 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.91 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.91 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.9 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.89 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.89 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.88 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.86 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.85 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.88 rifampicin
rpoB 761847 p.Cys681Ser missense_variant 0.89 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.89 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.88 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>G synonymous_variant 0.91 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.91 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.91 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.9 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.91 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.92 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.91 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.91 rifampicin
rpoB 761931 c.2125C>T synonymous_variant 0.92 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.93 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 0.93 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.93 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762027 c.2221_2223delCTCinsTTG synonymous_variant 0.91 rifampicin
rpoB 762032 c.2226C>G synonymous_variant 0.91 rifampicin
rpoB 762035 c.2229G>C synonymous_variant 0.91 rifampicin
rpoB 762053 c.2247T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.94 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.92 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.92 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.92 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.96 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.95 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.96 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.96 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.95 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.94 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.93 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 0.93 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.93 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.93 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.93 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.92 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 762443 c.-927G>C upstream_gene_variant 0.92 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.88 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.84 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.82 rifampicin Uncertain significance
rpoC 762521 c.-849C>G upstream_gene_variant 0.85 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.83 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.82 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.82 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.82 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.52 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.5 rifampicin
rpoC 762710 c.-660G>A upstream_gene_variant 0.68 rifampicin
rpoB 762729 p.Gln975Lys missense_variant 0.78 rifampicin
rpoC 762734 c.-636G>A upstream_gene_variant 0.75 rifampicin
rpoB 762736 p.Ala977Glu missense_variant 0.75 rifampicin
rpoB 762744 p.Gln980Ala missense_variant 0.72 rifampicin
rpoB 762750 p.Leu982Met missense_variant 0.72 rifampicin
rpoB 762753 c.2947T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762782 c.2976T>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.84 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.84 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.86 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.84 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.85 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762830 c.3024C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 762836 c.-534C>G upstream_gene_variant 0.85 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.94 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.94 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.94 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.94 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.94 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.9 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.87 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.87 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.88 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 763268 c.3462C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.69 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 0.53 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.5 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 0.86 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.86 rifampicin
rpoC 763441 c.72C>G synonymous_variant 0.92 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.95 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763658 c.289_291delCTTinsTTG synonymous_variant 0.96 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.92 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.94 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.93 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.95 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.94 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.94 rifampicin
rpoC 763768 c.399C>G synonymous_variant 0.94 rifampicin
rpoC 763780 c.411C>G synonymous_variant 0.94 rifampicin
rpoC 763783 c.414G>C synonymous_variant 0.94 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.94 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763819 c.450G>C synonymous_variant 0.94 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.94 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.93 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.93 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.94 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.93 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.93 rifampicin
rpoC 763885 c.516C>G synonymous_variant 0.92 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.92 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.92 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.92 rifampicin
rpoC 763945 c.576T>C synonymous_variant 0.9 rifampicin
rpoC 763960 c.591T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 763967 p.Gly200Ser missense_variant 0.87 rifampicin
rpoC 763978 c.609C>G synonymous_variant 0.86 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.87 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.88 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.88 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.89 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.88 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.9 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.89 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764110 c.741C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.91 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.9 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Gln missense_variant 0.91 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.91 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.93 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.94 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.93 rifampicin
rpoC 764282 c.913_915delTCGinsAGC synonymous_variant 0.93 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.93 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.93 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.93 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.92 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.91 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.9 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764573 c.1204_1206delCTTinsTTG synonymous_variant 0.9 rifampicin
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.9 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.9 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764695 c.1326T>C synonymous_variant 0.97 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.98 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.98 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.98 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764878 c.1509C>G synonymous_variant 0.97 rifampicin
rpoC 764893 c.1524T>C synonymous_variant 0.97 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.96 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.92 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.93 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.91 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765085 c.1716T>C synonymous_variant 0.91 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765208 c.1839T>C synonymous_variant 0.56 rifampicin
rpoC 765220 c.1851A>G synonymous_variant 0.63 rifampicin
rpoC 765223 c.1854G>C synonymous_variant 0.63 rifampicin
rpoC 765232 c.1863G>C synonymous_variant 0.63 rifampicin
rpoC 765244 c.1875T>G synonymous_variant 0.71 rifampicin
rpoC 765245 c.1877_1878insGCT disruptive_inframe_insertion 0.71 rifampicin
rpoC 765249 p.Leu627Ser missense_variant 0.71 rifampicin
rpoC 765250 c.1882_1884delAGC conservative_inframe_deletion 0.71 rifampicin
rpoC 765287 c.1918C>T synonymous_variant 0.93 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.93 rifampicin
rpoC 765298 c.1929G>T synonymous_variant 0.94 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.94 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765325 c.1956C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.95 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.95 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.97 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.97 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.97 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.96 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.92 rifampicin
rpoC 765452 p.Ala695Ser missense_variant 0.92 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 0.93 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.93 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.91 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.92 rifampicin
rpoC 765573 p.Asp735Gly missense_variant 0.92 rifampicin
rpoC 765577 c.2208G>C synonymous_variant 0.92 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.92 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.93 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.9 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.9 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 0.9 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.9 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.92 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.92 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.92 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.93 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.94 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765985 c.2616C>T synonymous_variant 0.95 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.95 rifampicin
rpoC 766015 c.2646G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.97 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.98 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.97 rifampicin
rpoC 766069 c.2700G>A synonymous_variant 0.97 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.99 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.99 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.99 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.96 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.94 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766299 p.Thr977Ile missense_variant 0.62 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.72 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.72 rifampicin
rpoC 766327 c.2958C>G synonymous_variant 0.84 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.85 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.9 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.91 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.9 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.9 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.92 rifampicin
rpoC 766444 c.3075C>G synonymous_variant 0.93 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.92 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.91 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.91 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.92 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766528 c.3159T>G synonymous_variant 0.92 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.93 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.93 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.92 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.92 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.92 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.94 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.94 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.93 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.93 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.93 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.92 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.94 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.93 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.92 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.93 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.93 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.94 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.94 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.94 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.94 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.94 rifampicin
rpoC 766978 c.3609C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.89 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.9 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.88 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.88 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 0.87 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>G synonymous_variant 0.84 rifampicin
rpoC 767158 c.3789T>G synonymous_variant 0.89 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.89 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.85 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.65 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.65 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.65 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 775817 c.2664T>C synonymous_variant 0.75 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775829 c.2652C>G synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 775832 p.Ala883Ser missense_variant 0.79 bedaquiline
clofazimine
mmpL5 775847 c.2634G>C synonymous_variant 0.83 bedaquiline
clofazimine
mmpL5 775851 p.Ser877Thr missense_variant 0.85 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.82 bedaquiline
clofazimine
mmpL5 775864 p.Ala873Ser missense_variant 0.82 bedaquiline
clofazimine
mmpL5 775865 c.2616T>G synonymous_variant 0.83 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.78 bedaquiline
clofazimine
mmpL5 775886 c.2595A>C synonymous_variant 0.83 bedaquiline
clofazimine
mmpL5 775898 c.2583G>A synonymous_variant 0.82 bedaquiline
clofazimine
mmpL5 775901 c.2580G>A synonymous_variant 0.75 bedaquiline
clofazimine
mmpL5 775904 c.2577G>A synonymous_variant 0.76 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.82 bedaquiline
clofazimine
mmpL5 775912 c.2569C>A synonymous_variant 0.76 bedaquiline
clofazimine
mmpL5 775916 c.2565T>G synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775937 c.2544G>C synonymous_variant 0.67 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.59 bedaquiline
clofazimine
mmpL5 775970 c.2511G>C synonymous_variant 0.39 bedaquiline
clofazimine
mmpL5 775975 c.2506T>C synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.82 bedaquiline
clofazimine
mmpL5 775990 c.2491C>T synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 775993 p.Glu830Lys missense_variant 0.45 bedaquiline
clofazimine
mmpL5 775994 p.Ile829Leu missense_variant 0.36 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.82 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.45 bedaquiline
clofazimine
mmpL5 776008 p.His825Tyr missense_variant 0.58 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 776030 c.2451G>C synonymous_variant 0.35 bedaquiline
clofazimine
mmpL5 776036 c.2445G>A synonymous_variant 0.31 bedaquiline
clofazimine
mmpL5 776039 c.2442C>A synonymous_variant 0.29 bedaquiline
clofazimine
mmpL5 776048 c.2433G>A synonymous_variant 0.29 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 0.87 bedaquiline
clofazimine
mmpL5 776056 p.Val809Leu missense_variant 0.85 bedaquiline
clofazimine
mmpL5 776057 c.2424G>A synonymous_variant 0.3 bedaquiline
clofazimine
mmpL5 776060 c.2421C>G synonymous_variant 0.57 bedaquiline
clofazimine
mmpL5 776063 c.2418C>G synonymous_variant 0.43 bedaquiline
clofazimine
mmpL5 776072 c.2409C>G synonymous_variant 0.39 bedaquiline
clofazimine
mmpL5 776075 p.Ala802Leu missense_variant 0.42 bedaquiline
clofazimine
mmpL5 776078 p.Ala801Ser missense_variant 0.72 bedaquiline
clofazimine
mmpL5 776081 c.2400G>T synonymous_variant 0.42 bedaquiline
clofazimine
mmpL5 776084 c.2397C>G synonymous_variant 0.84 bedaquiline
clofazimine
mmpL5 776087 c.2394C>G synonymous_variant 0.42 bedaquiline
clofazimine
mmpL5 776092 p.Ser797Gly missense_variant 0.41 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Ile missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
mmpL5 776120 c.2361C>T synonymous_variant 0.65 bedaquiline
clofazimine
mmpL5 776129 c.2352C>G synonymous_variant 0.67 bedaquiline
clofazimine
mmpL5 776132 p.Ala783Ser missense_variant 0.6 bedaquiline
clofazimine
mmpL5 776135 c.2346C>T synonymous_variant 0.6 bedaquiline
clofazimine
mmpL5 777101 c.1380C>G synonymous_variant 0.63 bedaquiline
clofazimine
mmpL5 777107 c.1374T>C synonymous_variant 0.63 bedaquiline
clofazimine
mmpL5 777110 c.1371T>C synonymous_variant 0.61 bedaquiline
clofazimine
mmpL5 777115 p.Met456Leu missense_variant 0.66 bedaquiline
clofazimine
mmpL5 777116 c.1365C>T synonymous_variant 0.66 bedaquiline
clofazimine
mmpL5 777133 p.Val450Ile missense_variant 0.8 bedaquiline
clofazimine
mmpL5 777143 c.1338G>A synonymous_variant 0.77 bedaquiline
clofazimine
mmpL5 777158 c.1323C>G synonymous_variant 0.81 bedaquiline
clofazimine
mmpL5 777164 c.1317C>G synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 777170 c.1311T>C synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 777173 c.1308C>G synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 777176 p.Glu435Asp missense_variant 0.79 bedaquiline
clofazimine
mmpL5 777179 c.1302G>C synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 777188 c.1293T>C synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 777191 c.1290C>G synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 777194 c.1287A>G synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 777203 c.1278G>C synonymous_variant 0.76 bedaquiline
clofazimine
mmpL5 777206 c.1275A>G synonymous_variant 0.76 bedaquiline
clofazimine
mmpL5 777214 p.Ala423Thr missense_variant 0.76 bedaquiline
clofazimine
mmpL5 777245 c.1236G>C synonymous_variant 0.66 bedaquiline
clofazimine
mmpL5 777251 c.1230C>A synonymous_variant 0.67 bedaquiline
clofazimine
mmpL5 777254 c.1227G>C synonymous_variant 0.67 bedaquiline
clofazimine
mmpL5 777268 c.1213C>T synonymous_variant 0.52 bedaquiline
clofazimine
mmpL5 777269 c.1212T>G synonymous_variant 0.52 bedaquiline
clofazimine
mmpL5 777278 c.1203G>A synonymous_variant 0.47 bedaquiline
clofazimine
rpsL 781556 c.-4delGinsCC upstream_gene_variant 0.4 streptomycin
rpsL 781571 c.12C>T synonymous_variant 0.65 streptomycin
rpsL 781608 p.Ser17Gly missense_variant 0.83 streptomycin
rpsL 781631 c.72G>C synonymous_variant 0.87 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.89 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.91 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.91 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.92 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.91 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.91 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.91 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.91 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.91 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.9 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.9 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.9 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.91 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.91 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.91 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.94 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.94 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.94 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.94 streptomycin Uncertain significance
rplC 800516 c.-293G>T upstream_gene_variant 0.88 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.93 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.94 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.94 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.95 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.94 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.95 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.95 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.95 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.96 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.94 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.94 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.95 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.95 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.95 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.94 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.96 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.96 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.95 linezolid
rplC 800794 c.-15_-9delAGATTGGinsGAGTT upstream_gene_variant 0.95 linezolid
rplC 800814 c.6A>G synonymous_variant 0.95 linezolid
rplC 800817 c.9A>T synonymous_variant 0.95 linezolid
rplC 800844 c.36T>C synonymous_variant 0.93 linezolid
rplC 800865 c.57A>G synonymous_variant 0.91 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.91 linezolid
rplC 800874 c.66A>G synonymous_variant 0.91 linezolid
rplC 800877 c.69A>C synonymous_variant 0.91 linezolid
rplC 800880 c.72A>G synonymous_variant 0.91 linezolid
rplC 800889 c.81C>G synonymous_variant 0.91 linezolid
rplC 800907 c.99C>G synonymous_variant 0.9 linezolid
rplC 800916 c.108A>G synonymous_variant 0.91 linezolid
rplC 800937 c.129A>G synonymous_variant 0.89 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.89 linezolid
rplC 800946 c.138T>C synonymous_variant 0.88 linezolid
rplC 800949 c.141T>C synonymous_variant 0.88 linezolid
rplC 800955 c.147C>G synonymous_variant 0.89 linezolid
rplC 800967 c.159C>G synonymous_variant 0.89 linezolid
rplC 800970 c.162T>C synonymous_variant 0.87 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.85 linezolid
rplC 800985 c.177A>G synonymous_variant 0.85 linezolid
rplC 800994 c.186C>G synonymous_variant 0.85 linezolid
rplC 801004 p.Leu66Val missense_variant 0.81 linezolid
rplC 801009 c.201A>C synonymous_variant 0.79 linezolid
rplC 801012 c.204T>C synonymous_variant 0.79 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.79 linezolid
rplC 801024 c.216C>G synonymous_variant 0.78 linezolid
rplC 801027 c.219C>G synonymous_variant 0.73 linezolid
rplC 801031 p.Val75Ile missense_variant 0.72 linezolid
rplC 801039 c.231A>G synonymous_variant 0.7 linezolid
rplC 801045 c.237A>G synonymous_variant 0.63 linezolid
rplC 801047 p.Tyr80Phe missense_variant 0.67 linezolid
rplC 801054 c.246G>C synonymous_variant 0.71 linezolid
rplC 801070 p.Asp88Asn missense_variant 0.61 linezolid
rplC 801073 p.Ser89Pro missense_variant 0.61 linezolid
rplC 801078 c.270T>C synonymous_variant 0.65 linezolid
rplC 801081 c.273C>G synonymous_variant 0.61 linezolid Not assoc w R - Interim
rplC 801085 p.Thr93Ala missense_variant 0.68 linezolid Uncertain significance
rplC 801090 c.282G>A synonymous_variant 0.73 linezolid
rplC 801099 c.291T>C synonymous_variant 0.78 linezolid
rplC 801102 c.294G>C synonymous_variant 0.78 linezolid
rplC 801105 c.297A>G synonymous_variant 0.75 linezolid
rplC 801109 c.301T>C synonymous_variant 0.8 linezolid Not assoc w R - Interim
rplC 801114 c.306C>G synonymous_variant 0.81 linezolid
rplC 801127 p.Ala107Thr missense_variant 0.88 linezolid
rplC 801132 c.324T>C synonymous_variant 0.88 linezolid
rplC 801147 c.339T>C synonymous_variant 0.86 linezolid
rplC 801150 c.342G>C synonymous_variant 0.86 linezolid
rplC 801153 c.345G>C synonymous_variant 0.87 linezolid
rplC 801156 c.348T>A synonymous_variant 0.87 linezolid
rplC 801171 c.363A>G synonymous_variant 0.85 linezolid
rplC 801174 c.366T>C synonymous_variant 0.85 linezolid
rplC 801183 c.375C>A synonymous_variant 0.89 linezolid
rplC 801222 c.414T>C synonymous_variant 0.86 linezolid
rplC 801228 c.420T>C synonymous_variant 0.88 linezolid
rplC 801246 c.438C>G synonymous_variant 0.89 linezolid
rplC 801249 c.441T>G synonymous_variant 0.9 linezolid
rplC 801255 c.447C>T synonymous_variant 0.91 linezolid
rplC 801267 c.459A>C synonymous_variant 0.89 linezolid
rplC 801270 c.462T>C synonymous_variant 0.88 linezolid
rplC 801276 c.468G>C synonymous_variant 0.89 linezolid
rplC 801279 c.471G>C synonymous_variant 0.88 linezolid
rplC 801282 c.474G>C synonymous_variant 0.89 linezolid
rplC 801301 c.493C>A synonymous_variant 0.89 linezolid
rplC 801312 c.504G>C synonymous_variant 0.89 linezolid
rplC 801324 c.516T>C synonymous_variant 0.91 linezolid
rplC 801336 c.528C>G synonymous_variant 0.88 linezolid
rplC 801339 c.531T>C synonymous_variant 0.89 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.89 linezolid
rplC 801348 c.540T>G synonymous_variant 0.89 linezolid
rplC 801357 c.549T>C synonymous_variant 0.89 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.88 linezolid
rplC 801396 c.588T>C synonymous_variant 0.8 linezolid
rplC 801402 c.594T>C synonymous_variant 0.76 linezolid
rplC 801405 c.597T>C synonymous_variant 0.75 linezolid
rplC 801417 c.609T>C synonymous_variant 0.71 linezolid
rplC 801423 c.615G>C synonymous_variant 0.72 linezolid
rplC 801438 c.630T>C synonymous_variant 0.65 linezolid
rplC 801442 p.Ile212Val missense_variant 0.58 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 0.33 linezolid
Rv1129c 1253465 c.1069_1070delAGinsTC synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253476 c.1059G>T synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253479 c.1056G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253482 c.1053G>C synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253491 c.1044A>T synonymous_variant 0.35 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253494 c.1041G>A synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253497 c.1038A>G synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253506 c.1029A>C synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253512 p.Lys341Asn missense_variant 0.39 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
rifampicin Uncertain significance
Rv1129c 1253524 c.1011C>G synonymous_variant 0.37 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253539 p.Ile332Met missense_variant 0.37 levofloxacin Uncertain significance
moxifloxacin
isoniazid Uncertain significance
rifampicin Uncertain significance
Rv1129c 1253540 c.993_994delGA frameshift_variant 0.37 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
rifampicin Uncertain significance
Rv1129c 1253545 c.990A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253549 p.Gln329Pro missense_variant 0.47 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
rifampicin Uncertain significance
Rv1129c 1253551 c.984G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253553 c.981_982insAA frameshift_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
rifampicin Uncertain significance
Rv1129c 1253560 c.975G>A synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
Rv1129c 1253566 c.969A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R
Rv1129c 1253572 c.963C>G synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid
rifampicin
Rv1129c 1253578 c.957C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
rifampicin Not assoc w R - Interim
fbiC 1303455 c.525C>G synonymous_variant 0.74 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303464 c.534A>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1303476 c.546G>C synonymous_variant 0.8 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303480 p.Gln184Glu missense_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303560 c.630G>C synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303611 c.681G>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1303638 c.708A>G synonymous_variant 0.91 pretomanid
delamanid
clofazimine
fbiC 1303659 c.729T>C synonymous_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303660 p.Val244Thr missense_variant 0.9 pretomanid
delamanid
clofazimine
fbiC 1303674 c.744C>G synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303701 c.771C>G synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303716 c.786C>T synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303728 c.798G>A synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>C synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.93 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 0.92 pretomanid
delamanid Not assoc w R - Interim