TB-Profiler result

Run: ERR736856
Summary

Run ID: ERR736856

Sample name:

Date: 2024-10-05T03:24:17.436475

Number of reads: 400924

Percentage reads mapped: 6.96

Median coverage: 1.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.94
La1.7.1 M.bovis None 0.07
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 756 c.756T>C synonymous_variant 1.0 isoniazid
dnaA 783 c.783C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 793 p.Val265Ile missense_variant 1.0 isoniazid Uncertain significance
dnaA 805 c.805T>C synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.92 isoniazid
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 877 c.877T>C synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
gyrB 6091 c.852G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6127 c.888G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6148 c.909C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6160 c.921C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrB 6169 c.930C>T synonymous_variant 0.28 levofloxacin
moxifloxacin
gyrB 6184 c.945C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6196 c.957C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAGC synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6235 c.996C>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6310 c.-992G>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6550 c.-752A>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6551 c.1312T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6580 c.-722C>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.93 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.67 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>A upstream_gene_variant 0.9 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 0.74 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.34 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrB 6721 c.1482C>T synonymous_variant 0.49 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6724 c.-578G>C upstream_gene_variant 0.61 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6749 p.Ala504Ser missense_variant 0.49 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6811 c.1572C>T synonymous_variant 0.75 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6838 c.-464C>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7153 c.-149G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7159 c.1920C>T synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7162 c.1923C>T synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 0.41 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7367 p.Gln22His missense_variant 0.55 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 0.53 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7424 c.123G>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7460 c.159C>G synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7463 c.162G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7556 c.255C>T synonymous_variant 0.29 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7622 c.321C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7643 c.342C>A synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7683 c.382_384delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGT synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.42 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTTG synonymous_variant 0.34 levofloxacin
moxifloxacin
gyrA 7802 c.501C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7823 c.522G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8382 c.1081C>T synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8387 c.1086C>T synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8390 c.1089C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8396 c.1095C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8405 c.1104C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8540 c.1239C>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8553 c.1252C>A synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8663 c.1362C>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8843 c.1542G>A synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8846 c.1545C>T synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8930 c.1629C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9017 c.1716C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9051 c.1750T>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9056 c.1755C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9062 c.1761C>G synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9065 c.1764C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9113 c.1812C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9213 p.Thr638Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.43 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9263 c.1962C>T synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.41 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 c.2007C>T synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 p.Ser675Thr missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 9329 c.2028C>G synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 9332 p.Asn677Lys missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>T synonymous_variant 0.31 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>T synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9374 c.2073G>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 491512 p.Asn244Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491536 c.754C>T synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491548 p.Ala256Pro missense_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491562 c.780C>T synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 491571 c.789C>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491595 c.813C>T synonymous_variant 0.29 pretomanid
delamanid
clofazimine
fgd1 491601 c.819T>C synonymous_variant 0.77 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491640 c.858G>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575659 c.312A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 0.77 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 0.69 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575689 c.342G>C synonymous_variant 0.88 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.83 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.74 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 0.72 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387_390delTTGTinsGTGC synonymous_variant 1.0 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 575749 c.402C>A synonymous_variant 0.87 isoniazid
ethionamide
mshA 575764 c.417C>G synonymous_variant 0.79 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 1.0 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 0.94 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 0.86 isoniazid
ethionamide
mshA 575800 c.453G>C synonymous_variant 0.57 isoniazid
ethionamide
mshA 575803 c.456C>T synonymous_variant 0.67 isoniazid Not assoc w R - Interim
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.68 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575845 c.498C>G synonymous_variant 0.56 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620358 c.468C>G synonymous_variant 0.92 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Ser missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>C synonymous_variant 0.61 kanamycin
capreomycin
amikacin
ccsA 620397 c.507C>G synonymous_variant 0.44 kanamycin
capreomycin
amikacin
ccsA 620409 c.519C>G synonymous_variant 0.48 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620424 c.534G>C synonymous_variant 0.5 kanamycin
capreomycin
amikacin
ccsA 620430 c.540C>T synonymous_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 620436 c.546T>A synonymous_variant 0.53 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620442 c.552G>C synonymous_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620460 c.570T>C synonymous_variant 0.77 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620619 c.729G>C synonymous_variant 0.8 kanamycin
capreomycin
amikacin
ccsA 620625 c.735A>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620658 c.768C>G synonymous_variant 0.46 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 0.86 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620712 c.822G>C synonymous_variant 0.59 kanamycin
capreomycin
amikacin
ccsA 620715 c.825C>T synonymous_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620724 c.834C>T synonymous_variant 0.84 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.35 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620736 c.846G>C synonymous_variant 0.75 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620754 c.864G>C synonymous_variant 0.71 kanamycin
capreomycin
amikacin
ccsA 620766 c.876C>G synonymous_variant 0.69 kanamycin
capreomycin
amikacin
Rv0565c 657617 c.-147G>C upstream_gene_variant 0.5 ethionamide
Rv0565c 657635 c.-167_-165delAGCinsTCG upstream_gene_variant 0.88 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657670 c.-200A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657692 c.-222C>T upstream_gene_variant 0.5 ethionamide
Rv0565c 657703 c.-233C>A upstream_gene_variant 1.0 ethionamide
hadA 731732 c.-198G>A upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.57 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.43 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731801 c.-129C>G upstream_gene_variant 0.43 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
hadA 731817 c.-113_-111delCTGinsTTC upstream_gene_variant 0.5 isoniazid
hadA 731822 c.-108G>A upstream_gene_variant 0.64 isoniazid
hadA 731823 c.-107_-105delCTGinsATC upstream_gene_variant 1.0 isoniazid
nusG 734415 c.162C>T synonymous_variant 0.33 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.53 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.58 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734566 c.313C>T synonymous_variant 0.32 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>C synonymous_variant 0.96 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.63 rifampicin Not assoc w R
rpoB 760118 c.312T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>C synonymous_variant 0.77 rifampicin
rpoB 760142 c.336C>G synonymous_variant 0.84 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.43 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 0.94 rifampicin
rpoB 760325 c.519G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>T synonymous_variant 0.76 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 0.67 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760412 c.606C>T synonymous_variant 0.44 rifampicin
rpoB 760415 c.609C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 760460 c.654G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 0.6 rifampicin
rpoB 760511 c.705G>C synonymous_variant 0.81 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 0.86 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 1.0 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 0.92 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 1.0 rifampicin
rpoB 760585 p.Asn260Ser missense_variant 0.9 rifampicin
rpoB 760590 p.Val262Ser missense_variant 0.5 rifampicin
rpoB 760595 c.789C>T synonymous_variant 0.91 rifampicin
rpoB 760611 c.805_807delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoB 760634 c.828T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.96 rifampicin
rpoB 760751 c.945G>C synonymous_variant 1.0 rifampicin
rpoB 760755 p.His317Asn missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 0.97 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.97 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760811 c.1005C>G synonymous_variant 0.62 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.94 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 0.95 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 1.0 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760887 p.Thr361Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 760916 c.1110C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761003 c.1197C>G synonymous_variant 0.47 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761087 c.1281C>G synonymous_variant 0.64 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.66 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 0.6 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 0.94 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761252 c.1446C>T synonymous_variant 0.29 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>A synonymous_variant 0.56 rifampicin
rpoB 761306 c.1500C>G synonymous_variant 0.47 rifampicin
rpoB 761312 c.1506G>C synonymous_variant 0.38 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 0.96 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.94 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.71 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.95 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.94 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761513 p.Glu569Asp missense_variant 1.0 rifampicin
rpoB 761516 c.1710G>C synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>T synonymous_variant 0.74 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 0.51 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 0.9 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 0.46 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.94 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.96 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.95 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.95 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.95 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.96 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.93 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 0.93 rifampicin Uncertain significance
rpoB 761873 c.2067A>T synonymous_variant 0.7 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.79 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.83 rifampicin
rpoB 761892 p.Ile696Val missense_variant 0.75 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.8 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.82 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.57 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.83 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 0.82 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 762038 c.2232C>T synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.33 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.4 rifampicin
rpoB 762134 c.2328C>T synonymous_variant 0.43 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 0.98 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.98 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762236 c.2430G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762299 c.2493G>C synonymous_variant 0.52 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 0.49 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 0.75 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 0.52 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.52 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 0.89 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762509 p.Ala902Pro missense_variant 1.0 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762557 c.-813G>C upstream_gene_variant 0.82 rifampicin
rpoB 762785 p.Asp993Glu missense_variant 0.89 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762814 p.Met1003Thr missense_variant 1.0 rifampicin Uncertain significance
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762830 c.3024C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 762831 c.-539_-537delAGCinsTCT upstream_gene_variant 0.54 rifampicin
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762896 c.-474G>C upstream_gene_variant 0.37 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 762920 c.-450C>G upstream_gene_variant 0.54 rifampicin
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 763022 c.-348C>G upstream_gene_variant 0.44 rifampicin
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 0.91 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.46 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763148 c.-222G>T upstream_gene_variant 0.46 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.9 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.95 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 0.43 rifampicin
rpoC 763193 c.-177C>T upstream_gene_variant 0.55 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 1.0 rifampicin
rpoC 763208 c.-162T>C upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoC 763217 c.-153G>C upstream_gene_variant 0.52 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.67 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 1.0 rifampicin
rpoC 763265 c.-105G>C upstream_gene_variant 1.0 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 1.0 rifampicin
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 1.0 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 0.75 rifampicin
rpoC 763441 c.72C>G synonymous_variant 0.64 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 0.43 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>T synonymous_variant 0.28 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.96 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763780 c.411C>G synonymous_variant 0.36 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763816 c.447C>G synonymous_variant 0.59 rifampicin
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763837 c.468G>C synonymous_variant 1.0 rifampicin
rpoC 763840 c.471G>C synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763861 c.492C>T synonymous_variant 1.0 rifampicin
rpoC 763867 c.498C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 763871 p.Gly168Ser missense_variant 0.72 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.48 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.98 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.41 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.32 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.94 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.94 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.94 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.95 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.36 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.94 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.94 rifampicin
rpoC 764002 c.633C>T synonymous_variant 0.76 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCTC synonymous_variant 0.92 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.92 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.71 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>T synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764227 c.858G>T synonymous_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.62 rifampicin
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764296 c.927G>C synonymous_variant 0.53 rifampicin
rpoC 764297 p.Met310Leu missense_variant 0.48 rifampicin
rpoC 764344 c.975C>T synonymous_variant 0.51 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764359 c.990C>G synonymous_variant 0.44 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764429 p.Leu354Phe missense_variant 0.44 rifampicin
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.51 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 0.47 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.46 rifampicin
rpoC 764536 c.1167G>T synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.45 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 764707 c.1338G>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 0.47 rifampicin
rpoC 764713 c.1344G>T synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.53 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.55 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.53 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>T synonymous_variant 0.44 rifampicin
rpoC 764857 c.1488G>T synonymous_variant 0.4 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.51 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.92 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCTC synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764920 c.1551G>C synonymous_variant 0.35 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 0.64 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 0.83 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>T synonymous_variant 0.7 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765403 c.2034G>C synonymous_variant 0.42 rifampicin
rpoC 765404 p.Leu679Asn missense_variant 0.42 rifampicin
rpoC 765409 c.2040T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765412 c.2043T>C synonymous_variant 0.39 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 1.0 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765533 p.Tyr722His missense_variant 0.39 rifampicin Uncertain significance
rpoC 765547 c.2178C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765559 c.2190G>C synonymous_variant 0.64 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 0.86 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 0.86 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 765844 c.2475C>G synonymous_variant 0.52 rifampicin
rpoC 765871 c.2502T>C synonymous_variant 0.47 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.91 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 0.74 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 0.85 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.94 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 0.58 rifampicin
rpoC 765962 c.2593_2595delTTGinsCTT synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766357 c.2988C>T synonymous_variant 0.56 rifampicin
rpoC 766363 c.2994G>C synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.8 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.84 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.46 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 1.0 rifampicin
rpoC 766433 c.3065delA frameshift_variant 0.67 rifampicin
rpoC 766442 p.Thr1025Val missense_variant 0.69 rifampicin
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>T synonymous_variant 0.8 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 0.94 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.94 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 0.94 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 0.94 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 1.0 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766931 p.Ala1188Ser missense_variant 0.94 rifampicin Uncertain significance
rpoC 766945 c.3576A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 1.0 rifampicin
rpoC 766960 c.3591C>T synonymous_variant 0.79 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767017 c.3648C>G synonymous_variant 0.49 rifampicin
rpoC 767020 c.3651C>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 767041 c.3672G>C synonymous_variant 0.42 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246His missense_variant 0.45 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Gly missense_variant 0.39 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.4 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.43 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.38 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775835 c.2646C>G synonymous_variant 0.55 bedaquiline
clofazimine
mmpL5 775847 c.2634G>T synonymous_variant 0.62 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 0.52 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775865 c.2616T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775885 p.Ile866Leu missense_variant 0.5 bedaquiline
clofazimine
mmpL5 775886 c.2595A>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775889 c.2592C>G synonymous_variant 0.37 bedaquiline
clofazimine
mmpL5 775893 p.His863Pro missense_variant 0.36 bedaquiline
clofazimine
mmpL5 775895 c.2586C>A synonymous_variant 0.43 bedaquiline
clofazimine
mmpL5 775904 c.2577G>A synonymous_variant 0.85 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.63 bedaquiline
clofazimine
mmpL5 775913 p.Ala856Ser missense_variant 0.6 bedaquiline
clofazimine
mmpL5 775916 c.2565T>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775921 c.2560C>T synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 775922 c.2559G>A synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 775937 c.2544G>C synonymous_variant 0.38 bedaquiline
clofazimine
mmpL5 775951 c.2530C>T synonymous_variant 0.82 bedaquiline
clofazimine
mmpL5 775966 p.Ala839Ser missense_variant 0.61 bedaquiline
clofazimine
mmpL5 775970 c.2511G>C synonymous_variant 0.43 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776030 c.2451G>C synonymous_variant 0.79 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 0.96 bedaquiline
clofazimine
mmpL5 776075 c.2406C>G synonymous_variant 0.68 bedaquiline
clofazimine
mmpL5 776081 c.2400G>C synonymous_variant 0.82 bedaquiline
clofazimine
mmpL5 776084 c.2397C>G synonymous_variant 0.84 bedaquiline
clofazimine
mmpL5 776087 c.2394C>G synonymous_variant 0.84 bedaquiline
clofazimine
mmpL5 776096 c.2385C>G synonymous_variant 0.54 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Leu missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776107 c.2374C>T synonymous_variant 0.6 bedaquiline
clofazimine
mmpL5 776120 c.2361C>T synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 776129 c.2352C>G synonymous_variant 0.48 bedaquiline
clofazimine
mmpL5 776132 p.Ala783Ser missense_variant 0.57 bedaquiline
clofazimine
mmpL5 776135 p.Ser782Ala missense_variant 0.46 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776681 p.Leu600Ile missense_variant 0.67 bedaquiline
clofazimine
mmpL5 776693 p.Val596Met missense_variant 0.53 bedaquiline
clofazimine
mmpL5 776715 p.Lys589Pro missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776726 p.Phe585Leu missense_variant 0.44 bedaquiline
clofazimine
mmpL5 776733 p.Ser583Asn missense_variant 1.0 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776741 c.1740C>G synonymous_variant 0.87 bedaquiline
clofazimine
mmpL5 776744 c.1737C>G synonymous_variant 0.87 bedaquiline
clofazimine
rpsL 781592 c.33T>C synonymous_variant 0.68 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>G synonymous_variant 0.7 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.78 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 0.8 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.82 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781703 c.144G>A synonymous_variant 0.66 streptomycin
rpsL 781709 c.150G>C synonymous_variant 0.38 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 0.89 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.84 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.97 streptomycin
rpsL 781733 c.174_177delGAGTinsCAGC synonymous_variant 0.95 streptomycin
rpsL 781742 c.183C>G synonymous_variant 0.71 streptomycin
rpsL 781748 c.189C>G synonymous_variant 0.54 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.88 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.8 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.97 streptomycin
rpsL 781763 c.204C>G synonymous_variant 0.41 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.77 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>T synonymous_variant 0.7 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.55 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.98 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.98 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.69 streptomycin
rpsL 781832 c.273T>C synonymous_variant 1.0 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.78 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.68 streptomycin
rpsL 781853 c.294C>T synonymous_variant 0.32 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.47 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781877 c.318T>C synonymous_variant 0.39 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>C synonymous_variant 1.0 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.46 streptomycin
rpsL 781907 c.348T>C synonymous_variant 1.0 streptomycin
rpsL 781910 c.351C>T synonymous_variant 0.44 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.97 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.98 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.41 streptomycin
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 0.42 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800591 c.-218C>T upstream_gene_variant 0.75 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800603 c.-206G>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 0.69 linezolid
rplC 800639 c.-170C>T upstream_gene_variant 0.47 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 0.97 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.95 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 0.4 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 0.4 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 0.44 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.95 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800729 c.-80G>C upstream_gene_variant 0.52 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 0.48 linezolid
rplC 800744 c.-65G>T upstream_gene_variant 0.47 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.7 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.86 linezolid
rplC 800768 c.-41C>A upstream_gene_variant 0.37 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.93 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800921 p.Arg38Leu missense_variant 0.53 linezolid
rplC 800928 c.120C>T synonymous_variant 1.0 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 800932 p.Pro42Thr missense_variant 0.47 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800964 c.156G>C synonymous_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 0.92 linezolid
rplC 801195 c.387G>C synonymous_variant 1.0 linezolid
rplC 801210 c.402T>C synonymous_variant 1.0 linezolid
rplC 801216 c.408C>T synonymous_variant 0.43 linezolid
rplC 801220 p.Ser138Ala missense_variant 1.0 linezolid
rplC 801231 c.423C>T synonymous_variant 0.54 linezolid
rplC 801237 c.429G>A synonymous_variant 0.93 linezolid
rplC 801249 c.441T>C synonymous_variant 0.5 linezolid
rplC 801252 c.444G>C synonymous_variant 0.88 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
fbiC 1303509 c.579G>C synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1303531 p.Met201Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1303548 c.618G>C synonymous_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303551 c.621G>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.86 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.8 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304515 p.Ala529Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>A synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304541 c.1611C>A synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.53 pretomanid
delamanid
clofazimine
fbiC 1304567 p.Phe546Tyr missense_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304709 c.1779C>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1304718 c.1788C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.88 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304751 c.1821C>T synonymous_variant 0.79 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304769 c.1839C>G synonymous_variant 0.83 pretomanid
delamanid
clofazimine
fbiC 1304772 c.1842C>T synonymous_variant 0.79 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304784 c.1854T>G synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 0.89 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>T synonymous_variant 0.87 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304835 c.1905G>C synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fbiC 1304844 c.1914C>T synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Met missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305007 p.Ile693Val missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiC 1305015 c.2085G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364649 c.237C>G synonymous_variant 0.92 pyrazinamide
sigE 1364671 c.259C>T synonymous_variant 0.84 pyrazinamide
sigE 1364679 c.267T>C synonymous_variant 0.89 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 0.7 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364694 c.282G>C synonymous_variant 0.64 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.67 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 0.83 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.6 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.9 pyrazinamide
atpE 1461132 p.Val30Ile missense_variant 1.0 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 1.0 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.94 bedaquiline
atpE 1461158 c.114T>C synonymous_variant 0.44 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 1.0 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 0.55 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 1.0 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 1.0 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 1.0 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 1.0 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 0.94 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 1.0 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 1.0 bedaquiline
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.41 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>T non_coding_transcript_exon_variant 0.85 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>A non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472324 n.479G>T non_coding_transcript_exon_variant 0.79 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin Uncertain significance
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.88 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.53 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472845 n.1000_1001insT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.8 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472849 n.1005delT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.68 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.8 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.4 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.36 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.55 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473814 n.157_158delATinsCA non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.42 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.46 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.39 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474110 n.453A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.32 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474288 n.631C>T non_coding_transcript_exon_variant 0.88 capreomycin
linezolid
rrl 1474290 n.633_647delTTTTCCTCTCCGGAGinsGTTTTT non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1474306 n.649A>C non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.86 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.41 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474711 n.1054_1063delGGTGTAAAGCinsCAAGTCCAAGAGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.53 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insC non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475637 n.1980T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475707 n.2050T>G non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105_2106delGCinsTT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.51 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 0.49 capreomycin
linezolid Uncertain significance
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373_2378delACCTCGinsGCAGCC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.37 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.44 capreomycin Uncertain significance
linezolid
rrl 1476108 n.2451T>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.46 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.98 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673517 c.-685G>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673523 c.-679G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673535 c.-667A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673568 c.-634C>G upstream_gene_variant 0.94 isoniazid
ethionamide
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
inhA 1673589 c.-613A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673703 c.-499C>T upstream_gene_variant 0.73 isoniazid
ethionamide
inhA 1673710 c.-492_-490delCTAinsATC upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 0.37 isoniazid
ethionamide
inhA 1673760 c.-442G>C upstream_gene_variant 0.38 isoniazid
ethionamide
inhA 1673767 c.-435A>G upstream_gene_variant 0.61 isoniazid
ethionamide
inhA 1673781 c.-421C>G upstream_gene_variant 0.57 isoniazid
ethionamide
inhA 1673787 c.-415G>C upstream_gene_variant 0.76 isoniazid
ethionamide
inhA 1673793 c.-409G>C upstream_gene_variant 0.47 isoniazid
ethionamide
inhA 1673799 c.-403T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673805 c.-397G>C upstream_gene_variant 0.41 isoniazid
ethionamide
inhA 1673808 c.-394A>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673905 c.-297T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674399 c.198A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674421 c.220T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674428 p.Gly76Asp missense_variant 1.0 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674435 c.234G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674450 c.249G>T synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674452 p.Ala84Glu missense_variant 0.38 isoniazid
ethionamide
inhA 1674463 p.Leu88Ile missense_variant 0.4 isoniazid
ethionamide
inhA 1674471 c.270G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674507 c.306G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674513 c.312C>T synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674514 p.Ile105Val missense_variant 0.93 isoniazid
ethionamide
inhA 1674537 c.336C>T synonymous_variant 0.7 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 1.0 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674600 c.399G>C synonymous_variant 0.71 isoniazid
ethionamide
inhA 1674601 p.Leu134Val missense_variant 0.52 isoniazid
ethionamide
inhA 1674604 c.403C>T synonymous_variant 0.58 isoniazid
ethionamide
inhA 1674621 c.420C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674669 c.468G>T synonymous_variant 0.87 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 0.96 isoniazid
ethionamide
inhA 1674703 c.502_504delTTGinsCTC synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674708 c.507G>A synonymous_variant 0.87 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.97 isoniazid
ethionamide
inhA 1674726 c.525G>C synonymous_variant 0.84 isoniazid
ethionamide
inhA 1674729 c.528G>A synonymous_variant 0.32 isoniazid
ethionamide
inhA 1674732 c.531C>T synonymous_variant 0.52 isoniazid
ethionamide
inhA 1674738 c.537C>G synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674745 p.Tyr182Val missense_variant 0.52 isoniazid
ethionamide
inhA 1674753 c.552G>A synonymous_variant 0.42 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674789 c.588G>C synonymous_variant 0.44 isoniazid
ethionamide
inhA 1674795 c.594G>C synonymous_variant 0.8 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 0.45 isoniazid
ethionamide
inhA 1674810 c.609C>G synonymous_variant 0.35 isoniazid
ethionamide
inhA 1674819 c.618G>C synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674822 c.621C>G synonymous_variant 0.41 isoniazid
ethionamide
inhA 1674825 c.624C>T synonymous_variant 0.56 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674828 p.Glu209Asp missense_variant 1.0 isoniazid
ethionamide
inhA 1674831 c.630G>A synonymous_variant 0.36 isoniazid
ethionamide
inhA 1674837 c.636C>G synonymous_variant 0.48 isoniazid
ethionamide
inhA 1674838 p.Ala213Lys missense_variant 0.4 isoniazid
ethionamide
inhA 1674846 p.Ile215Met missense_variant 1.0 isoniazid
ethionamide
inhA 1674858 c.657G>A synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674876 c.675C>T synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674883 p.Ile228Leu missense_variant 0.46 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 1.0 isoniazid
ethionamide
inhA 1674924 c.723G>C synonymous_variant 0.59 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 1.0 isoniazid
ethionamide
rpsA 1833547 c.6G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833724 c.183C>T synonymous_variant 0.97 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.31 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 0.93 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.93 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.73 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.92 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.47 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.95 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.54 pyrazinamide
rpsA 1833838 c.297G>T synonymous_variant 0.46 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.75 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.57 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.59 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 0.96 pyrazinamide
rpsA 1833995 c.454C>T synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
rpsA 1834000 c.459G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.51 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.93 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834123 c.582C>G synonymous_variant 0.48 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 1.0 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 0.45 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 0.49 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 0.67 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 0.49 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>T synonymous_variant 0.96 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.95 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.51 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 0.77 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.53 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.94 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.54 pyrazinamide
rpsA 1834540 c.999G>T synonymous_variant 0.46 pyrazinamide Not assoc w R - Interim
rpsA 1834543 c.1002C>G synonymous_variant 0.51 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.84 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.5 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.85 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834645 c.1104C>T synonymous_variant 0.47 pyrazinamide
rpsA 1834654 p.Glu371Asp missense_variant 0.5 pyrazinamide
rpsA 1834663 c.1122C>T synonymous_variant 0.49 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.49 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.52 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 0.56 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 0.93 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.91 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>C upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.91 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
katG 2155626 p.Ala162Ser missense_variant 1.0 isoniazid
katG 2155632 c.480A>G synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.9 isoniazid
katG 2155661 p.Val151Leu missense_variant 0.85 isoniazid
katG 2155668 c.444G>C synonymous_variant 0.55 isoniazid
katG 2155674 c.438G>C synonymous_variant 0.89 isoniazid
katG 2155680 c.432G>C synonymous_variant 0.88 isoniazid
katG 2155689 c.421_423delTTGinsCTC synonymous_variant 0.45 isoniazid Not assoc w R - Interim
katG 2155695 p.Ala139Val missense_variant 0.47 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 0.92 isoniazid
katG 2155728 c.384G>C synonymous_variant 0.89 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.97 isoniazid
kasA 2517953 c.-162C>T upstream_gene_variant 0.32 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.41 isoniazid
kasA 2517968 c.-147T>G upstream_gene_variant 0.86 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517980 c.-135C>G upstream_gene_variant 0.96 isoniazid
kasA 2517983 c.-132T>C upstream_gene_variant 0.46 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2517992 c.-123C>T upstream_gene_variant 0.43 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.53 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.9 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.92 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.92 isoniazid
kasA 2518174 c.60A>G synonymous_variant 0.94 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.95 isoniazid
kasA 2518223 c.109T>C synonymous_variant 0.94 isoniazid
kasA 2518228 c.114C>A synonymous_variant 0.93 isoniazid
kasA 2518240 c.126C>T synonymous_variant 0.82 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.91 isoniazid
kasA 2518537 c.423C>T synonymous_variant 0.67 isoniazid
kasA 2518564 c.450C>T synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.95 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Ala missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 0.65 isoniazid
kasA 2518582 c.468G>T synonymous_variant 0.94 isoniazid
kasA 2518583 p.Gln157Glu missense_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518591 c.477G>C synonymous_variant 1.0 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518612 c.498C>G synonymous_variant 0.89 isoniazid
kasA 2518624 c.510C>G synonymous_variant 0.33 isoniazid
kasA 2518627 c.513T>C synonymous_variant 0.67 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Phe missense_variant 1.0 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.72 isoniazid
kasA 2518714 c.600A>C synonymous_variant 1.0 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>C synonymous_variant 1.0 isoniazid
kasA 2518759 c.645C>G synonymous_variant 0.36 isoniazid
kasA 2518763 p.Ser217Thr missense_variant 0.27 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 1.0 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 1.0 isoniazid
kasA 2518792 c.678C>G synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>A synonymous_variant 0.56 isoniazid
kasA 2518822 c.708C>A synonymous_variant 0.73 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>C synonymous_variant 0.74 isoniazid
kasA 2518847 p.Leu245Met missense_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
ahpC 2726593 p.Val134Ala missense_variant 1.0 isoniazid
ahpC 2726600 c.408T>C synonymous_variant 1.0 isoniazid
ahpC 2726622 p.Ile144Val missense_variant 1.0 isoniazid
ahpC 2726633 c.441C>G synonymous_variant 0.81 isoniazid
ahpC 2726638 p.Ala149Val missense_variant 1.0 isoniazid
ahpC 2726642 c.450C>G synonymous_variant 0.81 isoniazid
ahpC 2726648 c.456T>G synonymous_variant 0.81 isoniazid
ahpC 2726654 c.462G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726657 c.465A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ahpC 2726663 c.471C>T synonymous_variant 1.0 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 1.0 isoniazid
ahpC 2726681 c.489A>T synonymous_variant 1.0 isoniazid
folC 2747308 c.291C>G synonymous_variant 0.7 para-aminosalicylic_acid
folC 2747314 c.285A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747341 p.Val86Leu missense_variant 1.0 para-aminosalicylic_acid
folC 2747347 c.252G>C synonymous_variant 0.85 para-aminosalicylic_acid
folC 2747355 p.Val82Ile missense_variant 0.85 para-aminosalicylic_acid
folC 2747356 p.Met81Ile missense_variant 1.0 para-aminosalicylic_acid
folC 2747362 p.Ala79Cys missense_variant 0.92 para-aminosalicylic_acid
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782546 c.1497C>G synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1488G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782564 c.1479G>C synonymous_variant 0.86 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782948 c.1095A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782957 c.1086A>G synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782969 c.1074A>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782972 c.1071G>T synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2782981 c.1062G>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783008 c.1035C>G synonymous_variant 0.93 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783038 p.Ala335Thr missense_variant 0.92 kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
rifampicin Uncertain significance
ethambutol Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2783152 c.891G>A synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783155 c.888C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783164 c.879G>A synonymous_variant 1.0 kanamycin
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783332 c.711T>C synonymous_variant 0.94 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 0.58 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.65 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.96 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.92 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
thyX 3067328 c.618G>C synonymous_variant 0.5 para-aminosalicylic_acid
thyX 3067349 c.597G>A synonymous_variant 0.73 para-aminosalicylic_acid
thyX 3067355 c.591A>C synonymous_variant 0.94 para-aminosalicylic_acid
thyX 3067364 c.582C>T synonymous_variant 0.78 para-aminosalicylic_acid
thyX 3067373 c.573C>G synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 0.55 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 0.79 para-aminosalicylic_acid
thyX 3067412 c.534C>G synonymous_variant 0.44 para-aminosalicylic_acid
thyX 3067418 c.528C>G synonymous_variant 0.48 para-aminosalicylic_acid
thyX 3067427 c.519G>C synonymous_variant 0.47 para-aminosalicylic_acid
thyX 3067430 c.516C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067439 c.507A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067457 c.489C>T synonymous_variant 0.67 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067669 c.277C>T synonymous_variant 0.75 para-aminosalicylic_acid
thyX 3067680 p.Cys89Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067748 c.198C>T synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067760 c.186G>C synonymous_variant 0.85 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.93 para-aminosalicylic_acid
thyX 3067773 p.Ala58Asp missense_variant 0.64 para-aminosalicylic_acid
thyX 3067778 c.168C>G synonymous_variant 0.64 para-aminosalicylic_acid
thyA 3073881 c.591C>T synonymous_variant 0.6 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
ald 3087251 c.432T>G synonymous_variant 1.0 cycloserine
ald 3087257 c.438T>C synonymous_variant 1.0 cycloserine
ald 3087263 c.444C>T synonymous_variant 1.0 cycloserine
ald 3087272 c.453A>C synonymous_variant 1.0 cycloserine
ald 3087281 c.462G>T synonymous_variant 1.0 cycloserine
ald 3087305 c.486G>C synonymous_variant 1.0 cycloserine
ald 3087308 c.489G>C synonymous_variant 1.0 cycloserine
ald 3087672 p.His285Asp missense_variant 1.0 cycloserine
ald 3087699 p.Leu294Val missense_variant 1.0 cycloserine
ald 3087704 c.885T>C synonymous_variant 1.0 cycloserine
ald 3087716 c.897G>C synonymous_variant 1.0 cycloserine
ald 3087727 p.Ala303Gly missense_variant 1.0 cycloserine
ald 3087738 p.Lys307Arg missense_variant 1.0 cycloserine
ald 3087751 p.Tyr311Phe missense_variant 1.0 cycloserine
lpqB 3624636 p.His92Arg missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
lpqB 3624659 c.252C>A synonymous_variant 0.5 rifampicin
bedaquiline
lpqB 3624665 c.246C>T synonymous_variant 0.47 rifampicin
bedaquiline
lpqB 3624674 p.Asn79Ser missense_variant 0.71 rifampicin
bedaquiline
lpqB 3624677 c.234C>G synonymous_variant 0.47 rifampicin
bedaquiline
lpqB 3624680 c.231T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624701 c.210T>G synonymous_variant 1.0 rifampicin
bedaquiline
lpqB 3624704 c.207G>C synonymous_variant 0.6 rifampicin
bedaquiline
lpqB 3624713 c.198C>T synonymous_variant 0.38 rifampicin
bedaquiline
lpqB 3624728 c.183C>T synonymous_variant 0.56 rifampicin
bedaquiline
lpqB 3625246 c.-336G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3625252 c.1362G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625255 c.-345T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625262 p.Tyr451Phe missense_variant 0.69 rifampicin
bedaquiline
mtrB 3625267 c.1347T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625270 c.-360G>C upstream_gene_variant 0.69 rifampicin
bedaquiline
lpqB 3625285 c.-375G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
lpqB 3625312 c.-402G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625325 p.His430Arg missense_variant 1.0 rifampicin
bedaquiline
lpqB 3625687 c.-777G>C upstream_gene_variant 0.64 rifampicin
bedaquiline
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625711 c.903C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625714 c.-804C>T upstream_gene_variant 0.57 rifampicin
bedaquiline
mtrB 3625720 c.894G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625729 c.885A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625732 c.882C>T synonymous_variant 0.39 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625735 c.879C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
lpqB 3625741 c.-831G>A upstream_gene_variant 0.55 rifampicin
bedaquiline
mtrB 3625747 c.867G>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3625753 p.Ala287Gln missense_variant 0.96 rifampicin
bedaquiline
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3625765 c.849C>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626704 c.-91C>T upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrA 3626711 p.Thr213Gln missense_variant 1.0 rifampicin
bedaquiline
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626729 c.-116G>A upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626749 c.601C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626750 c.-137T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626774 c.-163_-161delAGGinsCGT upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626780 c.-167T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626783 c.-170C>T upstream_gene_variant 0.39 rifampicin
bedaquiline
mtrB 3626786 c.-173A>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626792 c.-179G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626795 c.-182C>T upstream_gene_variant 0.58 rifampicin
bedaquiline
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626804 c.546A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626840 c.-227C>G upstream_gene_variant 0.47 rifampicin
bedaquiline
mtrB 3626843 c.-230G>C upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrA 3626846 c.504G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3626852 c.-239G>A upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626857 c.-244T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626861 c.-248C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626879 c.-266G>C upstream_gene_variant 0.65 rifampicin
bedaquiline
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3626894 c.-281C>T upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3626978 p.Asp124Glu missense_variant 1.0 rifampicin Uncertain significance
bedaquiline
mtrB 3626996 c.-383G>T upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3626999 c.-386G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627005 c.-392G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627014 c.-401G>C upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3627017 c.-404G>A upstream_gene_variant 0.68 rifampicin
bedaquiline
mtrA 3627041 p.Ile103Val missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627044 c.-431C>T upstream_gene_variant 0.96 rifampicin
bedaquiline
mtrA 3627056 c.294C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627068 c.282T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627071 c.-458G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627080 c.270T>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627098 c.252A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627110 c.-497G>C upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrA 3627119 c.231T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627125 c.-512C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627137 c.-526_-524delTTGinsCTC upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3627143 c.-530G>C upstream_gene_variant 0.9 rifampicin
bedaquiline
mtrB 3627152 c.-539C>T upstream_gene_variant 0.69 rifampicin
bedaquiline
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627187 c.163T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrA 3627188 c.162A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627203 c.-590C>G upstream_gene_variant 0.93 rifampicin
bedaquiline
mtrB 3627215 c.-602G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627224 c.-611G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627227 c.-614T>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627233 p.Thr39Ser missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627236 c.-623T>C upstream_gene_variant 0.75 rifampicin
bedaquiline
mtrB 3627254 c.-641C>G upstream_gene_variant 0.67 rifampicin
bedaquiline
mtrB 3627263 c.-650C>G upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627266 c.-653A>G upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrA 3627269 c.81G>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
bedaquiline
mtrB 3627272 c.-659G>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627296 c.-683T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627301 c.-688T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrA 3627305 p.Ala15Pro missense_variant 1.0 rifampicin
bedaquiline
mtrB 3627314 c.-701C>T upstream_gene_variant 0.53 rifampicin
bedaquiline
mtrB 3627317 c.-704T>C upstream_gene_variant 1.0 rifampicin
bedaquiline
mtrB 3627323 c.-712_-710delTTGinsCTT upstream_gene_variant 0.74 rifampicin
bedaquiline
mtrB 3627326 c.-713T>C upstream_gene_variant 0.74 rifampicin
bedaquiline
rpoA 3877534 p.Val325Ala missense_variant 1.0 rifampicin
rpoA 3877545 c.963G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877560 c.948C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877566 p.Ser314Thr missense_variant 1.0 rifampicin
rpoA 3877569 p.Pro313Ala missense_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoA 3877590 c.918G>C synonymous_variant 0.88 rifampicin
rpoA 3877593 c.915C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877596 c.912G>C synonymous_variant 0.48 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.48 rifampicin
rpoA 3877638 c.870T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoA 3877647 c.861C>T synonymous_variant 0.84 rifampicin
rpoA 3877656 c.852T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877668 c.840A>G synonymous_variant 0.95 rifampicin
rpoA 3877671 c.837C>G synonymous_variant 0.95 rifampicin
rpoA 3877677 c.831G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3877680 c.828G>C synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877683 c.825G>C synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877695 c.813C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877710 c.798C>G synonymous_variant 0.59 rifampicin
rpoA 3877728 c.780C>G synonymous_variant 1.0 rifampicin
rpoA 3877731 c.777G>C synonymous_variant 0.58 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 0.45 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 0.43 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.735_738delGTCAinsCAGC synonymous_variant 1.0 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.37 rifampicin Not assoc w R - Interim
rpoA 3877794 c.714G>T synonymous_variant 0.58 rifampicin
rpoA 3877818 c.690A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 0.5 rifampicin
rpoA 3877836 c.672A>G synonymous_variant 0.45 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>T synonymous_variant 0.47 rifampicin
rpoA 3877842 c.666A>G synonymous_variant 0.5 rifampicin
rpoA 3877848 c.660C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 0.45 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.75 rifampicin
rpoA 3877869 c.639G>A synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>A synonymous_variant 1.0 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 0.93 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 c.600T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 0.98 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 1.0 rifampicin
rpoA 3877968 c.540C>G synonymous_variant 0.42 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877974 c.534G>C synonymous_variant 0.61 rifampicin
rpoA 3877986 c.522G>C synonymous_variant 0.33 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877992 c.516C>G synonymous_variant 0.5 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 1.0 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.82 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.76 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 1.0 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 1.0 rifampicin
rpoA 3878127 c.381G>C synonymous_variant 0.7 rifampicin
rpoA 3878143 p.Gly122Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878145 c.363C>G synonymous_variant 0.52 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878163 c.345C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878166 c.342C>A synonymous_variant 0.36 rifampicin
rpoA 3878187 c.321C>A synonymous_variant 0.4 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 0.8 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878238 c.270C>T synonymous_variant 0.32 rifampicin
rpoA 3878241 c.267G>A synonymous_variant 0.6 rifampicin
rpoA 3878244 c.264G>A synonymous_variant 0.4 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.88 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.91 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 0.94 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.92 rifampicin
rpoA 3878358 c.150C>G synonymous_variant 1.0 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 1.0 rifampicin
rpoA 3878367 c.141C>G synonymous_variant 0.91 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.82 rifampicin
rpoA 3878373 c.135G>C synonymous_variant 0.95 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 1.0 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878394 c.114G>T synonymous_variant 0.76 rifampicin
rpoA 3878400 c.108T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878995 c.-488A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 1.0 rifampicin
rpoA 3879013 c.-508_-506delGAAinsAAC upstream_gene_variant 1.0 rifampicin
rpoA 3879016 c.-509A>C upstream_gene_variant 0.92 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879037 c.-530G>T upstream_gene_variant 0.9 rifampicin
rpoA 3879043 c.-536C>A upstream_gene_variant 0.9 rifampicin
rpoA 3879046 c.-539G>A upstream_gene_variant 0.9 rifampicin
rpoA 3879049 c.-542A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879073 c.-566A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-582_-581delCAinsGC upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879097 c.-590C>G upstream_gene_variant 0.57 rifampicin
clpC1 4038329 c.2376G>A synonymous_variant 0.57 pyrazinamide
clpC1 4038350 c.2355C>G synonymous_variant 0.43 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038380 c.2325C>G synonymous_variant 0.55 pyrazinamide
clpC1 4038383 c.2322G>C synonymous_variant 0.81 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038401 c.2302_2304delTTGinsCTC synonymous_variant 0.38 pyrazinamide
clpC1 4038410 c.2295C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038416 c.2289C>G synonymous_variant 0.48 pyrazinamide
clpC1 4038419 c.2286T>C synonymous_variant 0.95 pyrazinamide
clpC1 4038428 c.2277G>C synonymous_variant 0.89 pyrazinamide
clpC1 4038434 c.2271G>C synonymous_variant 0.4 pyrazinamide
clpC1 4038440 c.2265C>G synonymous_variant 0.61 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038460 p.Leu749Met missense_variant 1.0 pyrazinamide
clpC1 4038461 c.2244G>C synonymous_variant 0.65 pyrazinamide
clpC1 4038474 p.Ser744Thr missense_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 1.0 pyrazinamide
clpC1 4038488 p.Ala739Gly missense_variant 0.62 pyrazinamide
clpC1 4038499 p.Ser736Gly missense_variant 0.74 pyrazinamide
clpC1 4038519 p.Arg729Lys missense_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038533 p.Arg724Gln missense_variant 1.0 pyrazinamide
clpC1 4038536 c.2169C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038551 c.2154C>G synonymous_variant 0.47 pyrazinamide
clpC1 4038563 c.2142C>T synonymous_variant 0.36 pyrazinamide
clpC1 4038587 c.2118C>A synonymous_variant 0.9 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038602 c.2103G>C synonymous_variant 0.34 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 1.0 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 1.0 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038677 p.Pro676Ala missense_variant 0.64 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.91 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 0.78 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 0.89 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038755 c.1950G>C synonymous_variant 0.35 pyrazinamide
clpC1 4038767 c.1938G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 0.86 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 0.98 pyrazinamide
clpC1 4038791 c.1914G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.99 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.99 pyrazinamide
clpC1 4038827 c.1878G>A synonymous_variant 0.5 pyrazinamide
clpC1 4038842 c.1863G>C synonymous_variant 0.5 pyrazinamide
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.53 pyrazinamide
clpC1 4038860 c.1845G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>C synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.97 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.97 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038932 c.1773G>C synonymous_variant 0.66 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038986 p.Asp573Glu missense_variant 0.39 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 0.87 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039103 c.1602T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039118 c.1587C>G synonymous_variant 0.93 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039154 c.1551G>C synonymous_variant 0.47 pyrazinamide
clpC1 4039169 c.1536A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.7 pyrazinamide
clpC1 4039178 c.1527G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039181 c.1522_1524delTTGinsCTC synonymous_variant 0.48 pyrazinamide
clpC1 4039187 c.1518G>T synonymous_variant 0.93 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.92 pyrazinamide
clpC1 4039199 p.Ala502Glu missense_variant 0.53 pyrazinamide
clpC1 4039220 c.1485G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
clpC1 4039241 c.1464G>C synonymous_variant 0.53 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.98 pyrazinamide
clpC1 4039295 c.1410A>G synonymous_variant 0.64 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.76 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039319 p.Ala462Gly missense_variant 0.76 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039334 c.1371G>C synonymous_variant 0.37 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 0.88 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 0.41 pyrazinamide
clpC1 4039349 c.1356C>T synonymous_variant 0.67 pyrazinamide
clpC1 4039358 c.1347C>T synonymous_variant 0.46 pyrazinamide
clpC1 4039361 c.1344C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 0.79 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 0.51 pyrazinamide
clpC1 4039511 c.1194G>A synonymous_variant 0.43 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039559 c.1146C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.38 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 0.53 pyrazinamide Uncertain significance
clpC1 4039574 c.1131G>C synonymous_variant 0.94 pyrazinamide
clpC1 4039575 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039589 c.1116G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039592 c.1113G>C synonymous_variant 0.89 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.95 pyrazinamide
clpC1 4039640 c.1065C>G synonymous_variant 0.42 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039655 c.1050G>C synonymous_variant 0.48 pyrazinamide
clpC1 4039661 c.1044T>G synonymous_variant 0.51 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039670 c.1035G>T synonymous_variant 0.57 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 0.87 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.54 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 0.42 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 0.81 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 0.73 pyrazinamide
clpC1 4039763 c.942C>T synonymous_variant 0.34 pyrazinamide Not assoc w R - Interim
clpC1 4039769 c.936C>G synonymous_variant 0.73 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.55 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.61 pyrazinamide
clpC1 4039793 c.912C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039802 c.903G>C synonymous_variant 0.36 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>C synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.93 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 0.62 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039889 c.816G>C synonymous_variant 0.69 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.47 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>A synonymous_variant 0.78 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.4 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.45 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040015 c.690G>T synonymous_variant 0.4 pyrazinamide
clpC1 4040018 c.687G>C synonymous_variant 0.42 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040048 c.657C>T synonymous_variant 0.38 pyrazinamide Not assoc w R - Interim
clpC1 4040087 c.618G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.97 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.44 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 0.89 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4040168 c.537G>C synonymous_variant 0.91 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.68 pyrazinamide
clpC1 4040237 c.468C>T synonymous_variant 0.58 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.41 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.76 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 0.39 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040270 c.435C>T synonymous_variant 0.33 pyrazinamide
clpC1 4040273 c.432T>C synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.65 pyrazinamide
clpC1 4040279 c.426C>G synonymous_variant 0.4 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.73 pyrazinamide
clpC1 4040300 c.405C>T synonymous_variant 0.35 pyrazinamide
clpC1 4040306 c.399G>C synonymous_variant 0.88 pyrazinamide
clpC1 4040309 c.396C>G synonymous_variant 0.33 pyrazinamide Not assoc w R - Interim
clpC1 4040324 c.381G>C synonymous_variant 0.71 pyrazinamide
clpC1 4040336 c.369G>T synonymous_variant 0.38 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.33 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 0.67 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040441 c.264C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040465 c.240T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040477 c.228G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040480 c.225T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040498 c.207G>A synonymous_variant 0.63 pyrazinamide Not assoc w R - Interim
clpC1 4040522 c.183T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.89 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.58 pyrazinamide Not assoc w R - Interim
clpC1 4040546 c.159G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040570 c.135C>A synonymous_variant 0.67 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.96 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040585 c.120A>G synonymous_variant 0.95 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.9 pyrazinamide
clpC1 4040594 c.111G>T synonymous_variant 0.9 pyrazinamide
clpC1 4040597 c.108C>A synonymous_variant 0.87 pyrazinamide
clpC1 4040600 c.105A>G synonymous_variant 0.9 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.95 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.95 pyrazinamide
clpC1 4040644 c.61A>C synonymous_variant 0.96 pyrazinamide
clpC1 4040648 c.57G>A synonymous_variant 0.32 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.89 pyrazinamide
clpC1 4040690 c.15T>C synonymous_variant 0.6 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040696 c.9A>G synonymous_variant 0.93 pyrazinamide
clpC1 4040699 c.6C>T synonymous_variant 0.93 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044147 c.135C>G synonymous_variant 1.0 pyrazinamide
panD 4044150 c.132A>G synonymous_variant 1.0 pyrazinamide
panD 4044153 c.129G>A synonymous_variant 0.53 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044165 c.117G>C synonymous_variant 1.0 pyrazinamide
panD 4044171 c.111C>T synonymous_variant 0.48 pyrazinamide
panD 4044180 p.Asp34Glu missense_variant 1.0 pyrazinamide
panD 4044186 c.94_96delTTGinsCTC synonymous_variant 0.47 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044210 c.72C>T synonymous_variant 0.58 pyrazinamide
panD 4044216 c.66C>T synonymous_variant 0.4 pyrazinamide
panD 4044231 p.Cys17Gln missense_variant 1.0 pyrazinamide
panD 4044258 c.24G>C synonymous_variant 0.73 pyrazinamide
panD 4044261 c.21G>A synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
glpK 4138511 c.1245C>T synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138523 c.1233C>G synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138529 c.1227G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138532 c.1224G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138535 c.1221T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138568 c.1188A>G synonymous_variant 0.97 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138596 p.Phe387Tyr missense_variant 0.85 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138606 c.1150T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138619 c.1137C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
streptomycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138625 c.1131G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138631 c.1125C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138634 c.1122G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138643 c.1113A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
glpK 4138655 c.1101G>A synonymous_variant 0.8 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138661 c.1095T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138667 c.1089G>C synonymous_variant 0.66 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138670 c.1086G>C synonymous_variant 0.32 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138676 c.1080T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138681 p.Met359Val missense_variant 0.96 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138682 c.1074C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138696 p.Pro354Ser missense_variant 0.96 levofloxacin
moxifloxacin
isoniazid Uncertain significance
streptomycin
rifampicin Uncertain significance
ethambutol Uncertain significance
glpK 4138697 c.1059C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138718 c.1038T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138724 c.1032A>G synonymous_variant 0.72 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138727 c.1029C>G synonymous_variant 0.38 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138730 c.1026C>G synonymous_variant 0.66 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138742 c.1014C>T synonymous_variant 0.53 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138745 c.1011G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138751 c.1005T>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138757 c.999A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138769 c.987G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138772 c.984G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138796 c.960A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138802 c.954G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138805 c.951C>T synonymous_variant 0.63 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138808 c.948G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138817 c.939T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138822 p.Asn312Asp missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138823 c.933G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138829 c.927A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138844 c.912C>G synonymous_variant 0.73 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4138847 c.909A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139602 c.154C>A synonymous_variant 0.9 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139637 p.Ala40Gly missense_variant 1.0 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139647 p.Ala37Thr missense_variant 0.58 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
glpK 4139652 p.His35Ala missense_variant 0.75 levofloxacin
moxifloxacin
isoniazid
streptomycin
rifampicin
ethambutol
embC 4239514 c.-349A>T upstream_gene_variant 0.6 ethambutol
embC 4239526 c.-337_-336delGGinsAC upstream_gene_variant 1.0 ethambutol
embC 4239540 c.-323T>C upstream_gene_variant 1.0 ethambutol
embC 4239546 c.-317C>T upstream_gene_variant 0.92 ethambutol
embC 4239566 c.-297G>C upstream_gene_variant 0.58 ethambutol
embC 4239569 c.-294A>C upstream_gene_variant 0.92 ethambutol
embC 4240717 c.855T>C synonymous_variant 1.0 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.48 ethambutol Not assoc w R - Interim
embC 4240735 c.873C>G synonymous_variant 0.42 ethambutol
embC 4240766 c.904C>A synonymous_variant 0.39 ethambutol
embC 4240771 c.909G>T synonymous_variant 0.37 ethambutol
embC 4240780 c.918T>C synonymous_variant 0.68 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>T synonymous_variant 1.0 ethambutol
embC 4240822 c.960C>G synonymous_variant 0.36 ethambutol
embC 4240825 c.963G>A synonymous_variant 0.74 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.42 ethambutol
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240855 c.993G>C synonymous_variant 0.42 ethambutol
embC 4241008 c.1146G>A synonymous_variant 0.8 ethambutol
embC 4241017 c.1155T>C synonymous_variant 1.0 ethambutol
embC 4241023 c.1161T>A synonymous_variant 1.0 ethambutol
embC 4241024 p.Val388Phe missense_variant 1.0 ethambutol
embC 4241038 c.1176G>C synonymous_variant 0.96 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241047 c.1185C>G synonymous_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241056 c.1194C>G synonymous_variant 0.82 ethambutol
embC 4241071 c.1209C>G synonymous_variant 0.82 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241109 p.Ala416Gly missense_variant 1.0 ethambutol
embC 4241113 c.1251G>A synonymous_variant 0.85 ethambutol Not assoc w R - Interim
embC 4241121 p.Ser420Asn missense_variant 1.0 ethambutol
embC 4241614 c.1752A>C synonymous_variant 1.0 ethambutol
embA 4242838 c.-395C>G upstream_gene_variant 1.0 ethambutol
embA 4242844 c.-389A>G upstream_gene_variant 1.0 ethambutol
embC 4242847 c.2985C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4242862 c.-371A>G upstream_gene_variant 1.0 ethambutol
embC 4242872 p.Asp1004Thr missense_variant 1.0 ethambutol
embC 4242878 p.Thr1006Val missense_variant 1.0 ethambutol
embA 4242907 c.-326G>C upstream_gene_variant 0.67 ethambutol
embA 4242919 c.-314A>G upstream_gene_variant 1.0 ethambutol
embB 4247462 p.Ser317Ala missense_variant 0.43 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247491 c.978G>C synonymous_variant 1.0 ethambutol
embB 4247494 c.981G>A synonymous_variant 0.43 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.48 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248133 c.1620C>G synonymous_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248158 p.Cys549Ser missense_variant 0.82 ethambutol
embB 4248200 p.Ile563Val missense_variant 0.83 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248214 c.1701C>G synonymous_variant 0.47 ethambutol
embB 4248225 p.Ala571Val missense_variant 0.5 ethambutol Uncertain significance
embB 4248242 p.Val577Ile missense_variant 0.7 ethambutol
embB 4248252 p.Gly580Ala missense_variant 1.0 ethambutol
embB 4248256 c.1743C>G synonymous_variant 0.55 ethambutol
embB 4248264 p.Phe584Cys missense_variant 0.68 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.73 ethambutol
embB 4248319 c.1806A>G synonymous_variant 1.0 ethambutol
embB 4248322 c.1809G>T synonymous_variant 0.67 ethambutol
aftB 4267592 p.Ala415Ser missense_variant 0.9 ethambutol
aftB 4267601 c.1236C>G synonymous_variant 0.91 ethambutol
aftB 4267624 p.Ser405Thr missense_variant 0.91 ethambutol
aftB 4267625 p.Tyr404Asp missense_variant 0.91 ethambutol