Run ID: SRR6458421
Sample name:
Date: 2024-04-15T15:18:06.098888
Number of reads: 1298659
Percentage reads mapped: 70.54
Median coverage: 50.0
Strain: lineage2.2.1
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage2 | East-Asian | RD105 | 0.93 |
lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 0.97 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 0.97 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
p.Ser450Leu | Assoc w R | |||
rpoC | p.Leu527Val | Uncertain significance | Mutation from literature | |
isoniazid | katG | p.Ser315Thr | Assoc w R | High-level resistance |
ethambutol | embB | p.Met306Val | Assoc w R | |
p.His312Arg | Mutation from literature | |||
pyrazinamide | pncA | p.Gly97Ser | Assoc w R | |
streptomycin | rpsL | p.Lys43Arg | Assoc w R | |
rrs | n.462C>T | Uncertain significance | Mutation from literature | |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | eis | c.-10G>A | Assoc w R | Can only confer resistance if genetically linked to a functional Eis |
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
fbiC | c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.1039_1041delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 0.24 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 0.48 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
rpoB | 761155 | p.Ser450Leu | missense_variant | 0.59 | rifampicin | Assoc w R | |
rpoC | 764948 | p.Leu527Val | missense_variant | 0.81 | rifampicin | Uncertain significance | Mutation from literature |
rpsL | 781687 | p.Lys43Arg | missense_variant | 0.77 | streptomycin | Assoc w R | |
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.35 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303969 | c.1039_1041delGTTinsAC | frameshift_variant&missense_variant | 0.27 | delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.45 | streptomycin | Uncertain significance | Mutation from literature |
katG | 2155168 | p.Ser315Thr | missense_variant | 0.93 | isoniazid | Assoc w R | High-level resistance |
pncA | 2288953 | p.Gly97Ser | missense_variant | 1.0 | pyrazinamide | Assoc w R | |
eis | 2715342 | c.-10G>A | upstream_gene_variant | 1.0 | kanamycin | Assoc w R | Can only confer resistance if genetically linked to a functional Eis |
embB | 4247429 | p.Met306Val | missense_variant | 0.66 | ethambutol | Assoc w R | |
embB | 4247448 | p.His312Arg | missense_variant | 0.37 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 708 | c.708T>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.21 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.26 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.29 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.31 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.3 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.31 | isoniazid | |
dnaA | 843 | c.843T>C | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 846 | c.846T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 876 | c.876C>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 0.32 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 0.32 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 0.31 | isoniazid | |
dnaA | 933 | c.933C>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 942 | c.942C>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 0.31 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.26 | isoniazid | |
dnaA | 975 | c.975G>C | synonymous_variant | 0.26 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>G | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
dnaA | 993 | c.993A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 996 | c.996A>C | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
dnaA | 1002 | c.1002G>A | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1005 | c.1005G>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
dnaA | 1020 | c.1020C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1035 | c.1035A>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1050 | c.1050G>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1053 | c.1053C>G | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
dnaA | 1059 | c.1059C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1071 | c.1071C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1074 | c.1074C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.29 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.32 | isoniazid | Not assoc w R - Interim |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1177 | p.Ala393Ser | missense_variant | 0.31 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.28 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1293 | c.1293T>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1302 | c.1302C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1329 | c.1329A>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1332 | c.1332A>C | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
dnaA | 1335 | c.1335G>A | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1338 | c.1338T>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1356 | c.1356T>C | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 1359 | c.1359G>A | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 1365 | c.1365C>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1375 | c.1375T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1389 | c.1389C>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 1419 | c.1419C>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 0.21 | isoniazid | |
gyrB | 6190 | c.951A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6217 | c.978G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6325 | c.-977C>G | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6400 | c.-902C>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6727 | c.-575G>T | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6778 | c.-524C>T | upstream_gene_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6824 | c.1585C>T | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.44 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.43 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6911 | p.Asn558His | missense_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.48 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6931 | c.-371A>C | upstream_gene_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6937 | c.1698G>A | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6955 | c.-347G>A | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6970 | c.-332C>T | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6973 | c.1734G>A | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6976 | c.-326A>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7000 | c.-302C>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7006 | c.-296T>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7012 | c.1773G>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7018 | c.-284G>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7021 | c.-281G>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7060 | c.1821T>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7078 | c.-224A>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7081 | c.-221T>C | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7114 | c.-188C>A | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 7124 | c.1885_1887delTCGinsAC | frameshift_variant&missense_variant | 0.26 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrA | 7129 | c.-173T>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7132 | c.-170T>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7136 | c.-166T>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7141 | c.-161T>C | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7144 | c.-158A>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7487 | c.186C>G | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7490 | c.189C>T | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7626 | c.325C>T | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382A>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409T>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7727 | c.426G>C | synonymous_variant | 0.44 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 0.45 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7760 | c.459C>T | synonymous_variant | 0.42 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7835 | c.534A>G | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7838 | c.537C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7862 | c.561C>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7883 | c.582G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7884 | c.583_585delCGTinsGC | frameshift_variant&missense_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7898 | p.Asp199Glu | missense_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7919 | p.Glu206Asp | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7923 | p.His208Tyr | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7928 | p.Asp209Glu | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7942 | p.Glu214Ala | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7955 | c.654G>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7958 | c.657C>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7963 | p.Gly221Glu | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7970 | c.669T>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7976 | c.675C>A | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7979 | c.678G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7991 | c.690C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7992 | c.691_693delGCCinsTG | frameshift_variant&missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7997 | c.696A>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8010 | p.Ser237Thr | missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8020 | p.Thr240Ile | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8024 | c.723T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8027 | c.726T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8036 | c.735A>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8039 | c.738T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8054 | c.753T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8057 | c.756A>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8081 | c.780A>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8084 | c.783G>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8096 | c.795T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8129 | c.828T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8235 | c.934_936delTTAinsCG | frameshift_variant&missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8390 | c.1089C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8391 | p.Tyr364Leu | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8401 | p.Asp367Ala | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8438 | c.1137C>T | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8465 | c.1164C>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8472 | c.1171C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8498 | c.1197C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8528 | c.1227G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8531 | c.1230G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8535 | p.Glu412Gln | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8552 | c.1251C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8645 | c.1344C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8717 | c.1416C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8720 | c.1419G>A | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8732 | c.1431G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8951 | c.1650G>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.28 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9278 | c.1977G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9281 | c.1980C>G | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9311 | c.2010C>T | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9542 | c.2241T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9548 | c.2247T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
fgd1 | 490902 | c.120T>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>A | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490962 | c.180T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490968 | c.186C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490974 | c.192T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490998 | c.216T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491007 | c.225G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491010 | c.228C>G | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491013 | c.231C>G | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491031 | c.249C>G | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491038 | p.Ile86Val | missense_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491077 | p.Asn99Gly | missense_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491082 | c.300T>G | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491137 | p.Glu119Gln | missense_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Glu | missense_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491166 | c.384G>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491196 | c.414A>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.19 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.2 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491331 | c.549G>A | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
mshA | 574650 | c.-698A>C | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 574655 | c.-693C>G | upstream_gene_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 574664 | c.-684G>C | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 574671 | c.-677_-675delGCAinsCTG | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 574676 | c.-672G>C | upstream_gene_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 574683 | c.-665T>C | upstream_gene_variant | 0.21 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575689 | c.342G>C | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.23 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575719 | c.372C>T | synonymous_variant | 0.28 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.26 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
mshA | 575907 | p.Ala187Val | missense_variant | 0.94 | ethionamide | Not assoc w R |
isoniazid | Not assoc w R | |||||
ccsA | 620249 | p.Ser120Cys | missense_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.16 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>G | synonymous_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 0.17 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | p.Ile245Met | missense_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Uncertain significance | |||||
ccsA | 620631 | c.741T>C | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620703 | c.813G>C | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620710 | p.Val274Met | missense_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620730 | c.840C>T | synonymous_variant | 0.17 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.17 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620745 | c.855G>C | synonymous_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.24 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620784 | c.894C>G | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620787 | c.897C>G | synonymous_variant | 0.25 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 0.98 | ethionamide | Uncertain significance |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 0.17 | ethionamide | |
Rv0565c | 657639 | c.-169C>G | upstream_gene_variant | 0.19 | ethionamide | |
Rv0565c | 657641 | c.-171C>G | upstream_gene_variant | 0.2 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.2 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 0.21 | ethionamide | |
Rv0565c | 657686 | c.-216C>G | upstream_gene_variant | 0.22 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.22 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.25 | ethionamide | |
Rv0565c | 657719 | c.-249C>G | upstream_gene_variant | 0.32 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.34 | ethionamide | |
hadA | 731681 | c.-249A>C | upstream_gene_variant | 0.18 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 0.29 | isoniazid | |
hadA | 732304 | c.375C>T | synonymous_variant | 0.18 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.18 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.18 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.2 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.22 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.22 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.24 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.33 | isoniazid | |
hadA | 732389 | p.Ser154Thr | missense_variant | 0.3 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.3 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.3 | isoniazid | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.28 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.26 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.25 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.31 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.33 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.33 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
nusG | 734481 | c.228C>G | synonymous_variant | 0.33 | rifampicin | |
nusG | 734499 | c.246G>C | synonymous_variant | 0.41 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.32 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
nusG | 734595 | c.342C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
nusG | 734596 | c.343T>C | synonymous_variant | 0.26 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.28 | rifampicin | |
nusG | 734820 | c.567A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
nusG | 734826 | c.573A>G | synonymous_variant | 0.28 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
nusG | 734832 | c.579C>G | synonymous_variant | 0.27 | rifampicin | |
nusG | 734841 | c.588G>A | synonymous_variant | 0.25 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.25 | rifampicin | |
nusG | 734853 | c.600A>C | synonymous_variant | 0.23 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 0.23 | rifampicin | |
nusG | 734865 | c.612G>C | synonymous_variant | 0.24 | rifampicin | |
nusG | 734882 | p.Ala210Gly | missense_variant | 0.23 | rifampicin | |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760340 | c.534G>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.26 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.22 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760555 | p.Glu250Ala | missense_variant | 0.23 | rifampicin | |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.23 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.33 | rifampicin | |
rpoB | 760602 | p.Glu266Gln | missense_variant | 0.33 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>G | synonymous_variant | 0.42 | rifampicin | |
rpoB | 760721 | c.915C>G | synonymous_variant | 0.42 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 0.35 | rifampicin | |
rpoB | 760763 | c.957C>T | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760775 | c.969G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760821 | c.1015C>T | synonymous_variant | 0.4 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Pro | missense_variant | 0.48 | rifampicin | |
rpoB | 760859 | c.1053T>C | synonymous_variant | 0.49 | rifampicin | |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.52 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.52 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.61 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.6 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.61 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.64 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.67 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.73 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.74 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.76 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.76 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.72 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.79 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.77 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.54 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.54 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761171 | c.1365C>T | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761183 | c.1377T>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761222 | c.1416G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.48 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.42 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.34 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761437 | p.Ala544Asp | missense_variant | 0.31 | rifampicin | |
rpoB | 761439 | c.1633_1635delGACinsAG | frameshift_variant&missense_variant | 0.31 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761452 | p.Val549Ala | missense_variant | 0.3 | rifampicin | |
rpoB | 761457 | c.1651_1653delCCGinsGC | frameshift_variant&missense_variant | 0.3 | rifampicin | |
rpoB | 761462 | c.1656C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.34 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761687 | c.1881C>T | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsG | frameshift_variant&synonymous_variant | 0.23 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.23 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.25 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.25 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.24 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761847 | p.Cys681Ser | missense_variant | 0.22 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761864 | c.2058G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.21 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.21 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 761969 | c.2163G>A | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762027 | c.2221_2223delCTCinsTG | frameshift_variant&missense_variant | 0.36 | rifampicin | |
rpoB | 762032 | c.2226C>G | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762035 | c.2229G>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.36 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 0.34 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.37 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>G | synonymous_variant | 0.33 | rifampicin | |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.25 | rifampicin | |
rpoC | 762521 | c.-849C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.15 | rifampicin | |
rpoB | 762860 | c.3054G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.68 | rifampicin | Not assoc w R |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763076 | c.-294C>G | upstream_gene_variant | 0.33 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.33 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.3 | rifampicin | |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 0.28 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 0.27 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 0.28 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763220 | c.-150G>C | upstream_gene_variant | 0.31 | rifampicin | |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 763268 | c.3462C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 763283 | c.3477T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763284 | c.-86C>T | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 763316 | c.3510T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763322 | c.-48G>T | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 763343 | c.-27T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoC | 763351 | c.-19T>C | upstream_gene_variant | 0.19 | rifampicin | Uncertain significance |
rpoC | 763352 | c.-18T>A | upstream_gene_variant | 0.19 | rifampicin | Uncertain significance |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763441 | c.72C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763658 | c.289_291delCTTinsTG | frameshift_variant&missense_variant | 0.41 | rifampicin | |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>A | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.33 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763768 | c.399C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763783 | c.414G>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763819 | c.450G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763831 | c.462A>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.2 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.23 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.23 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763919 | c.550C>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 763960 | c.591T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763967 | p.Gly200Ser | missense_variant | 0.28 | rifampicin | |
rpoC | 763978 | c.609C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 0.32 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 764161 | c.792G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Gln | missense_variant | 0.37 | rifampicin | |
rpoC | 764203 | c.834G>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 764282 | c.913_915delTCGinsAGC | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764320 | c.951C>G | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.3 | rifampicin | |
rpoC | 764398 | c.1029G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764573 | c.1204_1206delCTTinsTG | frameshift_variant&missense_variant | 0.33 | rifampicin | |
rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765007 | c.1638T>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.28 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.26 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 0.26 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 765535 | c.2166C>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.35 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.33 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.43 | rifampicin | Not assoc w R - Interim |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.42 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.45 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.44 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765985 | c.2616C>T | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766009 | c.2640G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.38 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766069 | c.2700G>A | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.3 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.17 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.21 | rifampicin | |
rpoC | 766309 | c.2940G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766315 | c.2946C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 766327 | c.2958C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.3 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.38 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766531 | c.3162G>T | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.52 | rifampicin | |
rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.49 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.49 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | c.3238_3240delATCinsCG | frameshift_variant&missense_variant | 0.54 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.56 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 0.63 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.6 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.58 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.59 | rifampicin | |
rpoC | 766738 | c.3369G>T | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.45 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>C | synonymous_variant | 0.47 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 766978 | c.3609C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.34 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.31 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.37 | rifampicin | |
rpoC | 767074 | c.3705T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.25 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 767248 | c.3879C>T | synonymous_variant | 0.2 | rifampicin | |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775898 | c.2583G>A | synonymous_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775901 | c.2580G>A | synonymous_variant | 0.16 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.2 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775912 | c.2569C>A | synonymous_variant | 0.16 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 0.21 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.19 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776182 | p.Asp767Asn | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R | |||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.27 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.29 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.32 | streptomycin | |
rpsL | 781859 | c.300T>C | synonymous_variant | 0.3 | streptomycin | Not assoc w R - Interim |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.3 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.33 | streptomycin | Uncertain significance |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.19 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.22 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.29 | linezolid | |
rplC | 800690 | c.-119C>T | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.4 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.42 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.41 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 0.39 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.34 | linezolid | |
rplC | 800794 | c.-15_-9delAGATTGGinsGAGTT | upstream_gene_variant | 0.33 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.33 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.33 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.32 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.24 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.24 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.22 | linezolid | |
rplC | 800877 | c.69A>C | synonymous_variant | 0.21 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.22 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.22 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.17 | linezolid | |
rplC | 801127 | p.Ala107Thr | missense_variant | 0.15 | linezolid | |
rplC | 801183 | c.375C>A | synonymous_variant | 0.19 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 0.24 | linezolid | |
rplC | 801228 | c.420T>C | synonymous_variant | 0.25 | linezolid | |
rplC | 801246 | c.438C>G | synonymous_variant | 0.26 | linezolid | |
rplC | 801249 | c.441T>G | synonymous_variant | 0.25 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.22 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
fbiC | 1303534 | p.Ser202Ala | missense_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303560 | c.630G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303611 | c.681G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303638 | c.708A>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303660 | p.Val244Thr | missense_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303701 | c.771C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303716 | c.786C>T | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.37 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303881 | c.951G>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303920 | c.990C>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303923 | c.993C>T | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303929 | c.999G>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303973 | p.Gly348Ala | missense_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303981 | p.Val351Ile | missense_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303995 | c.1065C>T | synonymous_variant | 0.28 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304001 | c.1071C>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304080 | p.Ala384Ser | missense_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304097 | c.1167G>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304523 | c.1593G>T | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304526 | c.1596T>A | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304545 | p.Val539Thr | missense_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304628 | c.1698G>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304670 | c.1740G>T | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304671 | p.Val581Thr | missense_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304675 | p.Gly582Glu | missense_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.24 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304790 | c.1860C>G | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.25 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>G | synonymous_variant | 0.2 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364667 | c.255T>C | synonymous_variant | 0.2 | pyrazinamide | |
sigE | 1364676 | c.264C>G | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364679 | c.267T>C | synonymous_variant | 0.21 | pyrazinamide | |
sigE | 1364691 | c.279T>C | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364712 | c.300T>C | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364718 | c.306C>T | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364727 | c.315C>T | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364736 | c.324T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364742 | c.330A>G | synonymous_variant | 0.25 | pyrazinamide | |
sigE | 1364748 | c.336G>C | synonymous_variant | 0.29 | pyrazinamide | |
sigE | 1364763 | c.351T>C | synonymous_variant | 0.27 | pyrazinamide | |
sigE | 1364767 | c.355A>C | synonymous_variant | 0.26 | pyrazinamide | |
sigE | 1364784 | c.372C>G | synonymous_variant | 0.29 | pyrazinamide | |
sigE | 1364802 | c.390C>A | synonymous_variant | 0.28 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364820 | c.408A>G | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364835 | c.423C>G | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.31 | pyrazinamide | |
sigE | 1364862 | c.450C>G | synonymous_variant | 0.25 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.26 | pyrazinamide | |
sigE | 1364866 | c.454_456delGCTinsTG | frameshift_variant&missense_variant | 0.26 | pyrazinamide | Uncertain significance |
sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 0.24 | pyrazinamide | Uncertain significance |
sigE | 1364904 | p.Asp164Glu | missense_variant | 0.21 | pyrazinamide | |
Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
isoniazid | Uncertain significance | |||||
pyrazinamide | Uncertain significance | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.19 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.19 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.25 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.25 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.29 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472030 | n.185G>A | non_coding_transcript_exon_variant | 0.29 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.29 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>C | non_coding_transcript_exon_variant | 0.36 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.35 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.33 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.36 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.26 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.3 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.35 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.34 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.35 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445delCinsTTT | non_coding_transcript_exon_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473944 | n.287G>A | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473945 | n.288T>C | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1474051 | n.394T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474056 | n.399T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1474104 | n.447G>A | non_coding_transcript_exon_variant | 0.47 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 0.47 | capreomycin | |
linezolid | ||||||
rrl | 1474112 | n.455T>A | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 0.49 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474291 | n.634_649delTTTCCTCTCCGGAGGAinsC | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474376 | n.719T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474904 | n.1247G>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1474956 | n.1299C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474959 | n.1302C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474962 | n.1306delG | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | |
linezolid | ||||||
rrl | 1474991 | n.1334T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.3 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1475267 | n.1610G>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475333 | n.1676T>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.51 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.55 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.37 | capreomycin | |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.42 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476025 | n.2368G>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | |
linezolid | ||||||
rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476034 | n.2377C>A | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.41 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.37 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.41 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476725 | n.3068C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1673610 | c.-592C>T | upstream_gene_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1673616 | c.-586A>G | upstream_gene_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.2 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673633 | p.Ser65Asn | missense_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1673646 | c.-556T>C | upstream_gene_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1673658 | c.-544G>A | upstream_gene_variant | 0.23 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673660 | p.Ala74Glu | missense_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1673664 | c.-538A>G | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
inhA | 1673667 | c.-535A>G | upstream_gene_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1673679 | c.-523T>G | upstream_gene_variant | 0.31 | ethionamide | |
isoniazid | ||||||
inhA | 1673709 | c.-493C>T | upstream_gene_variant | 0.25 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673710 | c.271_273delCTAinsAC | frameshift_variant&missense_variant | 0.25 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673716 | p.Ala93Lys | missense_variant | 0.26 | ethionamide | |
isoniazid | ||||||
inhA | 1673730 | c.-472C>G | upstream_gene_variant | 0.26 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673733 | p.Met98Ile | missense_variant | 0.26 | ethionamide | |
isoniazid | ||||||
inhA | 1673742 | c.-460C>G | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673750 | p.Lys104Arg | missense_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674368 | p.Ala56Glu | missense_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1674379 | c.178C>T | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1674382 | p.Leu61Ile | missense_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1674415 | p.Ala72Thr | missense_variant | 0.16 | ethionamide | |
isoniazid | ||||||
inhA | 1674480 | c.279T>C | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674486 | c.285T>C | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674489 | c.288G>C | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.24 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.27 | ethionamide | |
isoniazid | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674627 | c.426T>C | synonymous_variant | 0.24 | ethionamide | |
isoniazid | ||||||
inhA | 1674630 | c.429C>G | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674654 | c.453G>C | synonymous_variant | 0.27 | ethionamide | |
isoniazid | ||||||
inhA | 1674693 | c.492C>G | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.32 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.33 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.48 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1833790 | c.249T>A | synonymous_variant | 0.51 | pyrazinamide | |
rpsA | 1833799 | c.258C>G | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.5 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833862 | c.321G>T | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834150 | c.609G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834153 | c.612T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 0.28 | pyrazinamide | Uncertain significance |
rpsA | 1834157 | c.616T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834162 | c.621A>G | synonymous_variant | 0.28 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834165 | c.624A>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834169 | p.Thr210Ala | missense_variant | 0.28 | pyrazinamide | Uncertain significance |
rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834186 | c.645C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834189 | c.648G>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834195 | c.654G>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834201 | c.660C>T | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834225 | c.684C>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834261 | c.720A>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834297 | c.756C>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.41 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.47 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834498 | c.957C>T | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834558 | c.1017C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834594 | c.1053C>T | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834606 | c.1065C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834666 | c.1125G>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834669 | c.1128G>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834688 | c.1147_1149delAGTinsTCC | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1834726 | c.1185C>A | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Pro | missense_variant | 0.25 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834765 | c.1224A>G | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.21 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.34 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.32 | linezolid | |
tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 0.35 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.35 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.36 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.37 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.33 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.34 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.3 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.3 | linezolid | |
tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.3 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
bacA | 2064933 | c.-205A>G | upstream_gene_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064936 | c.-208C>A | upstream_gene_variant | 0.32 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064945 | c.-217G>A | upstream_gene_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.38 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064963 | c.-235G>C | upstream_gene_variant | 0.26 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.26 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064978 | c.-250G>C | upstream_gene_variant | 0.25 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064979 | c.-253_-251delGGCinsCT | upstream_gene_variant | 0.25 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064984 | c.-256A>G | upstream_gene_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064993 | c.-265T>C | upstream_gene_variant | 0.27 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
kasA | 2517947 | c.-168C>T | upstream_gene_variant | 0.27 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.25 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.22 | isoniazid | |
kasA | 2517992 | c.-123C>G | upstream_gene_variant | 0.18 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.27 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518540 | c.426T>G | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 0.39 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.41 | isoniazid | |
kasA | 2518621 | c.507G>A | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518687 | c.573C>T | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518690 | c.576C>T | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.46 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518717 | c.603C>T | synonymous_variant | 0.44 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.52 | isoniazid | |
kasA | 2518741 | c.627G>C | synonymous_variant | 0.49 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518768 | c.654C>G | synonymous_variant | 0.46 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518792 | c.678C>G | synonymous_variant | 0.45 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518822 | c.708C>G | synonymous_variant | 0.49 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518855 | c.741C>G | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.38 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518906 | c.792A>G | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.23 | isoniazid | |
kasA | 2518927 | c.813C>G | synonymous_variant | 0.17 | isoniazid | |
folC | 2747359 | c.240C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.19 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783020 | c.1023G>C | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.23 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783062 | c.981C>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.33 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783110 | c.933C>A | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783158 | c.885A>G | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783203 | c.840C>T | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>T | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783320 | c.723C>T | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783362 | c.681G>C | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783365 | c.678C>T | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783373 | p.Glu224Gln | missense_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783416 | c.625_627delATCinsGG | frameshift_variant&missense_variant | 0.25 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783425 | c.616_618delCCCinsGG | frameshift_variant&missense_variant | 0.26 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783434 | c.609C>G | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783494 | c.549C>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783605 | c.438T>C | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783611 | c.432C>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783629 | c.414C>T | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783641 | c.402G>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783656 | c.387G>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783659 | c.384A>G | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783691 | c.352C>T | synonymous_variant | 0.31 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783761 | c.282G>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783766 | p.Met93Leu | missense_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783773 | c.270A>G | synonymous_variant | 0.43 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.42 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783794 | c.249G>A | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783815 | c.228A>G | synonymous_variant | 0.43 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783833 | c.210G>C | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783860 | p.Asp61Glu | missense_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.39 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.39 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.26 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784330 | c.-288G>A | upstream_gene_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784357 | c.-316_-315delTTinsAC | upstream_gene_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784366 | c.-324G>C | upstream_gene_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784375 | c.-333T>C | upstream_gene_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784381 | c.-339T>C | upstream_gene_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784390 | c.-348G>C | upstream_gene_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784396 | c.-354A>C | upstream_gene_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784428 | c.-386T>C | upstream_gene_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784429 | c.-387A>G | upstream_gene_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784432 | c.-390A>C | upstream_gene_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784455 | c.-413A>C | upstream_gene_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784456 | c.-414A>C | upstream_gene_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784472 | c.-430C>A | upstream_gene_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2752c | 3064962 | c.1230C>A | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064973 | p.Ala407Ser | missense_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064980 | c.1212C>A | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066350 | c.-159T>A | upstream_gene_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
thyX | 3067376 | c.570G>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067391 | c.555G>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067412 | c.534C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067451 | c.495G>A | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067463 | c.481_483delATCinsGA | frameshift_variant&missense_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067466 | c.480G>C | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067470 | p.Asn159Ser | missense_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067500 | p.Lys149Arg | missense_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.32 | para-aminosalicylic_acid | |
thyX | 3067526 | c.420C>G | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.28 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067560 | p.Arg129His | missense_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067570 | p.Ala126Pro | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067571 | c.375C>T | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067577 | p.Glu123Asp | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067582 | p.Met122Leu | missense_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067586 | c.360C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067601 | c.345G>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067604 | c.342G>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067610 | p.Lys112Asn | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067613 | c.333G>A | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067640 | c.306G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067643 | c.303C>T | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067682 | c.264G>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067685 | c.261A>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067688 | c.258G>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyX | 3067694 | c.252G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067724 | c.222G>A | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067742 | c.204A>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3073874 | p.Ile200Val | missense_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073878 | c.594G>A | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3073893 | c.579C>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3073926 | c.546G>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
thyA | 3074001 | c.471C>G | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>A | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.36 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.35 | para-aminosalicylic_acid | |
thyA | 3074056 | p.Glu139Pro | missense_variant | 0.34 | para-aminosalicylic_acid | |
thyA | 3074061 | c.411A>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyA | 3074076 | c.396C>G | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyA | 3074082 | c.390G>C | synonymous_variant | 0.32 | para-aminosalicylic_acid | |
thyA | 3074097 | c.375C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074100 | c.372T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074106 | c.366T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074117 | c.355C>T | synonymous_variant | 0.24 | para-aminosalicylic_acid | |
thyA | 3074120 | c.352T>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3074130 | c.342G>C | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3074199 | c.273G>A | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074205 | p.Glu89Asp | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3074214 | c.258T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3074217 | c.255T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3074235 | c.237C>T | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
ald | 3086731 | c.-89A>G | upstream_gene_variant | 1.0 | cycloserine | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
lpqB | 3624166 | p.Met249Leu | missense_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624172 | p.Val247Ile | missense_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624173 | c.738A>C | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624188 | c.723G>C | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624191 | c.720C>G | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624194 | c.717C>A | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624200 | c.711A>G | synonymous_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624209 | c.702A>C | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624224 | c.687T>C | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624241 | c.670C>T | synonymous_variant | 0.22 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624242 | c.669A>G | synonymous_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624245 | c.666A>G | synonymous_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624401 | c.510C>T | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624713 | c.198C>T | synonymous_variant | 0.2 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrB | 3625313 | p.Arg434Lys | missense_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625569 | c.1045T>C | synonymous_variant | 0.24 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625592 | p.Ser341Asn | missense_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625627 | c.-717C>T | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.28 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.32 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.32 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.32 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625735 | c.879C>A | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.29 | bedaquiline | |
rifampicin | Uncertain significance | |||||
mtrB | 3625762 | c.852A>G | synonymous_variant | 0.28 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.3 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.3 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.19 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626562 | p.Pro18Ser | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrB | 3626684 | c.-71G>T | upstream_gene_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.21 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.21 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.22 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.27 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.29 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.34 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.33 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.34 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.34 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.38 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626912 | c.438T>C | synonymous_variant | 0.39 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626930 | c.-317A>T | upstream_gene_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.36 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626942 | c.-329A>G | upstream_gene_variant | 0.37 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.36 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.38 | bedaquiline | |