TB-Profiler result

Run: SRR1640750
Summary

Run ID: SRR1640750

Sample name:

Date: 2024-10-04T05:53:58.420870

Number of reads: 911268

Percentage reads mapped: 57.8

Median coverage: 37.0

Strain:

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4.1.2 Euro-American None 0.98
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol embB p.His312Arg Mutation from literature
p.Leu359Ile Uncertain significance Mutation from literature
p.Ala388Gly Mutation from literature
pyrazinamide
streptomycin rrs n.462C>T Uncertain significance Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.55 streptomycin Uncertain significance Mutation from literature
embB 4247448 p.His312Arg missense_variant 0.73 ethambutol Mutation from literature
embB 4247588 p.Leu359Ile missense_variant 0.65 ethambutol Uncertain significance Mutation from literature
embB 4247676 p.Ala388Gly missense_variant 0.41 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 522 c.522T>C synonymous_variant 0.45 isoniazid Not assoc w R - Interim
dnaA 525 c.525T>C synonymous_variant 0.48 isoniazid
dnaA 534 c.534T>G synonymous_variant 0.5 isoniazid
dnaA 540 c.540C>G synonymous_variant 0.49 isoniazid
dnaA 543 c.543C>G synonymous_variant 0.49 isoniazid
dnaA 571 c.571T>C synonymous_variant 0.54 isoniazid
dnaA 576 c.576G>C synonymous_variant 0.54 isoniazid
dnaA 582 c.582A>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 591 c.591C>G synonymous_variant 0.56 isoniazid
dnaA 600 c.600T>C synonymous_variant 0.53 isoniazid
dnaA 609 c.609C>G synonymous_variant 0.52 isoniazid
dnaA 610 c.610C>T synonymous_variant 0.52 isoniazid
dnaA 636 c.636C>G synonymous_variant 0.5 isoniazid
dnaA 645 c.645A>G synonymous_variant 0.51 isoniazid Not assoc w R - Interim
dnaA 654 c.654A>G synonymous_variant 0.5 isoniazid
dnaA 660 c.660G>C synonymous_variant 0.51 isoniazid Not assoc w R - Interim
dnaA 663 c.663A>C synonymous_variant 0.53 isoniazid
dnaA 669 c.669C>T synonymous_variant 0.5 isoniazid
dnaA 672 c.672T>C synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 675 c.675C>G synonymous_variant 0.5 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 0.53 isoniazid Not assoc w R - Interim
dnaA 682 c.682_684delTTGinsCTC synonymous_variant 0.54 isoniazid
dnaA 690 c.690G>C synonymous_variant 0.57 isoniazid
dnaA 693 c.693A>C synonymous_variant 0.57 isoniazid
dnaA 705 c.705A>G synonymous_variant 0.59 isoniazid
dnaA 708 c.708T>C synonymous_variant 0.63 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.66 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.68 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.7 isoniazid
dnaA 771 c.771A>C synonymous_variant 0.65 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.65 isoniazid
dnaA 786 c.786C>T synonymous_variant 0.62 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.62 isoniazid Not assoc w R - Interim
dnaA 805 c.805T>C synonymous_variant 0.59 isoniazid
dnaA 813 c.813C>T synonymous_variant 0.57 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.57 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.54 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.52 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.52 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.52 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 0.54 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.56 isoniazid
dnaA 876 c.876C>G synonymous_variant 0.56 isoniazid
dnaA 877 c.877T>C synonymous_variant 0.56 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.53 isoniazid
dnaA 897 c.897A>G synonymous_variant 0.55 isoniazid
dnaA 909 c.909A>C synonymous_variant 0.55 isoniazid Not assoc w R - Interim
dnaA 912 c.912T>C synonymous_variant 0.55 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.55 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.55 isoniazid Not assoc w R - Interim
dnaA 927 c.927G>A synonymous_variant 0.57 isoniazid
dnaA 933 c.933C>G synonymous_variant 0.57 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.52 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.52 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.5 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.48 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.48 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.52 isoniazid
dnaA 984 c.984T>C synonymous_variant 0.46 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>G synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 993 c.993A>G synonymous_variant 0.38 isoniazid
dnaA 996 c.996A>C synonymous_variant 0.38 isoniazid Not assoc w R - Interim
dnaA 1002 c.1002G>A synonymous_variant 0.41 isoniazid
dnaA 1005 c.1005G>C synonymous_variant 0.41 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.43 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.44 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.43 isoniazid
dnaA 1035 c.1035A>G synonymous_variant 0.5 isoniazid
dnaA 1047 c.1047A>G synonymous_variant 0.47 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.47 isoniazid
dnaA 1053 c.1053C>G synonymous_variant 0.48 isoniazid Not assoc w R - Interim
dnaA 1059 c.1059C>G synonymous_variant 0.45 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.45 isoniazid
dnaA 1071 c.1071C>G synonymous_variant 0.45 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.45 isoniazid
dnaA 1092 c.1092T>C synonymous_variant 0.54 isoniazid Not assoc w R - Interim
dnaA 1098 c.1098A>G synonymous_variant 0.53 isoniazid
dnaA 1104 c.1104T>C synonymous_variant 0.53 isoniazid
dnaA 1110 c.1110T>C synonymous_variant 0.53 isoniazid
dnaA 1125 c.1125G>C synonymous_variant 0.53 isoniazid
dnaA 1152 c.1152A>G synonymous_variant 0.59 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.58 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.58 isoniazid
dnaA 1164 c.1164A>T synonymous_variant 0.59 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.56 isoniazid Not assoc w R - Interim
dnaA 1176 c.1176A>G synonymous_variant 0.53 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.54 isoniazid
dnaA 1191 c.1191T>C synonymous_variant 0.57 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.58 isoniazid
dnaA 1204 c.1204C>T synonymous_variant 0.59 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.6 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.6 isoniazid
dnaA 1242 c.1242G>C synonymous_variant 0.65 isoniazid
dnaA 1245 c.1245G>C synonymous_variant 0.68 isoniazid Not assoc w R - Interim
dnaA 1254 c.1254T>C synonymous_variant 0.65 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.63 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.58 isoniazid
dnaA 1290 c.1290G>A synonymous_variant 0.58 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.58 isoniazid
dnaA 1302 c.1302C>G synonymous_variant 0.61 isoniazid
dnaA 1314 c.1314A>G synonymous_variant 0.58 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 0.58 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 0.57 isoniazid
dnaA 1332 c.1332A>T synonymous_variant 0.55 isoniazid
dnaA 1335 c.1335G>A synonymous_variant 0.55 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 0.55 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 0.55 isoniazid
dnaA 1356 c.1356T>C synonymous_variant 0.55 isoniazid Not assoc w R - Interim
dnaA 1365 c.1365C>G synonymous_variant 0.56 isoniazid
dnaA 1371 c.1371T>G synonymous_variant 0.53 isoniazid
dnaA 1375 c.1375T>C synonymous_variant 0.54 isoniazid
dnaA 1383 c.1383A>G synonymous_variant 0.51 isoniazid
dnaA 1389 c.1389C>G synonymous_variant 0.49 isoniazid
dnaA 1392 c.1392A>G synonymous_variant 0.46 isoniazid
dnaA 1395 c.1395G>C synonymous_variant 0.45 isoniazid
dnaA 1404 c.1404T>C synonymous_variant 0.45 isoniazid
dnaA 1407 c.1407T>C synonymous_variant 0.45 isoniazid
dnaA 1413 c.1413A>C synonymous_variant 0.45 isoniazid
dnaA 1416 c.1416C>G synonymous_variant 0.43 isoniazid
dnaA 1419 c.1419C>G synonymous_variant 0.43 isoniazid
dnaA 1431 c.1431A>G synonymous_variant 0.37 isoniazid
dnaA 1461 c.1461C>A synonymous_variant 0.29 isoniazid
dnaA 1464 c.1464T>C synonymous_variant 0.29 isoniazid
dnaA 1470 c.1470C>G synonymous_variant 0.26 isoniazid
dnaA 1473 c.1473T>C synonymous_variant 0.24 isoniazid Not assoc w R - Interim
gyrB 6169 c.930C>G synonymous_variant 0.3 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.41 levofloxacin
moxifloxacin
gyrB 6209 c.970C>T synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6217 c.978G>C synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.56 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>T synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6299 c.1060C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6319 c.1080G>C synonymous_variant 0.58 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 6325 c.-977C>G upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6361 c.-941G>A upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6362 c.-940T>C upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 6379 c.-923C>G upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 0.57 levofloxacin
moxifloxacin
gyrA 6388 c.-914T>C upstream_gene_variant 0.6 levofloxacin
moxifloxacin
gyrA 6400 c.-902C>G upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6403 c.-899T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 6415 c.-887G>C upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 6670 c.-632G>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.59 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.62 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>G synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6760 c.-542G>C upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 0.72 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.75 levofloxacin
moxifloxacin
gyrB 6824 c.1585C>T synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6841 c.1602T>C synonymous_variant 0.77 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 0.77 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6862 c.1623C>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6878 c.1639T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6881 c.1642T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6904 c.-398C>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 0.76 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 0.74 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 0.69 levofloxacin
moxifloxacin
gyrA 6931 c.-371A>C upstream_gene_variant 0.65 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 6937 c.1698G>A synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrB 6952 c.1713C>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6955 c.-347G>A upstream_gene_variant 0.63 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 6973 c.1734G>A synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6976 c.-326A>G upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.56 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>G upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 0.58 levofloxacin
moxifloxacin
gyrB 7012 c.1773G>C synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7018 c.-284G>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7021 c.-281G>C upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7033 c.-269G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.41 levofloxacin
moxifloxacin
gyrB 7060 c.1821T>C synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrA 7165 c.-137C>G upstream_gene_variant 0.26 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.25 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7427 c.126G>C synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7571 c.270G>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7595 c.294C>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 7652 c.351C>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7683 c.382A>C synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 0.66 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7760 c.459C>T synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7799 c.498A>G synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>G synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7838 c.537C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 7884 p.Arg195Gly missense_variant 0.7 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7892 c.591G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.74 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.66 levofloxacin
moxifloxacin
gyrA 7928 p.Asp209Glu missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 7942 p.Glu214Ala missense_variant 0.6 levofloxacin
moxifloxacin
gyrA 7955 c.654G>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7958 c.657C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 7970 c.669T>G synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 7979 c.678G>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 7992 p.Ala231Ser missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 7997 c.696A>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8009 c.708A>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8010 p.Ser237Thr missense_variant 0.58 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 8024 c.723T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8027 c.726T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8036 c.735A>G synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8039 c.738T>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8054 c.753T>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8078 c.777A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8093 c.792C>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8096 c.795T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8283 p.Ile328Leu missense_variant 0.61 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8342 c.1041G>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8348 c.1047C>A synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8363 c.1062C>A synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8366 c.1065G>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8391 p.Tyr364His missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8498 c.1197C>T synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8537 c.1236G>A synonymous_variant 0.51 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8552 c.1251C>G synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 8556 p.Ala419Gln missense_variant 0.45 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8562 c.1261C>T synonymous_variant 0.45 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8603 c.1302A>G synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8619 c.1318T>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8627 c.1326C>G synonymous_variant 0.52 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8645 c.1344C>G synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8699 c.1398A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 0.6 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8756 c.1455A>G synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8762 c.1461G>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8765 p.Asp488Glu missense_variant 0.61 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8767 p.Arg489Lys missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8779 p.Asp493Ala missense_variant 0.68 levofloxacin
moxifloxacin
gyrA 8786 c.1485T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8796 p.Ile499Val missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 8801 c.1500G>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 8867 c.1566A>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8918 c.1617C>G synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8945 c.1644G>C synonymous_variant 0.55 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8951 c.1650G>A synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8966 c.1665C>G synonymous_variant 0.57 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8967 p.Ala556Arg missense_variant 0.57 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.61 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9023 c.1722A>T synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 9029 c.1728T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.56 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.5 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>C synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCTG synonymous_variant 0.43 levofloxacin
moxifloxacin
gyrA 9104 c.1803C>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9122 c.1821C>G synonymous_variant 0.39 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9134 c.1833C>G synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9143 c.1842T>C synonymous_variant 0.36 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.36 levofloxacin
moxifloxacin
gyrA 9152 c.1851C>T synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9153 p.Thr618Glu missense_variant 0.33 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 0.38 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 0.42 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9227 c.1926C>G synonymous_variant 0.4 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9233 c.1932C>T synonymous_variant 0.4 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.46 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9275 c.1974G>A synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9278 c.1977G>C synonymous_variant 0.48 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9281 c.1980C>G synonymous_variant 0.48 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.46 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.44 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 0.45 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 0.43 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.39 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.33 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9389 c.2088C>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9395 c.2094G>C synonymous_variant 0.35 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9518 c.2217A>G synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9521 c.2220C>T synonymous_variant 0.35 levofloxacin
moxifloxacin
gyrA 9527 c.2226A>G synonymous_variant 0.33 levofloxacin
moxifloxacin
gyrA 9542 c.2241T>C synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9545 c.2244A>G synonymous_variant 0.37 levofloxacin
moxifloxacin
gyrA 9548 c.2247T>C synonymous_variant 0.37 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
fgd1 490851 c.69A>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fgd1 490887 c.105G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 490902 c.120T>C synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fgd1 490932 c.150T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490948 p.Ser56Ala missense_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490962 c.180T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490968 c.186C>G synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490974 c.192T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490979 p.Asn66Thr missense_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490984 p.Leu68Ile missense_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490987 p.Leu69Thr missense_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 490998 c.216T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 491007 c.225G>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 491010 c.228C>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 491013 c.231C>G synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 491031 c.249C>G synonymous_variant 0.66 pretomanid
delamanid
clofazimine
fgd1 491038 p.Ile86Val missense_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491043 c.261T>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 491063 p.Gly94Ala missense_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491077 p.Asn99Gly missense_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>G synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491083 p.Val101Ile missense_variant 0.57 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fgd1 491094 c.312C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491106 c.324T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 0.67 pretomanid
delamanid
clofazimine
fgd1 491137 p.Glu119Gln missense_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 491144 p.Ala121Glu missense_variant 0.68 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491181 c.399T>C synonymous_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 491191 p.Gly137Arg missense_variant 0.72 pretomanid
delamanid
clofazimine
fgd1 491196 c.414A>G synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491202 c.420G>C synonymous_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 491203 p.Gln141Glu missense_variant 0.75 pretomanid
delamanid
clofazimine
fgd1 491212 p.Ser144Arg missense_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491217 c.435T>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491232 c.450T>C synonymous_variant 0.74 pretomanid
delamanid
clofazimine
fgd1 491241 p.Asp153Glu missense_variant 0.7 pretomanid
delamanid
clofazimine
fgd1 491244 c.462T>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.62 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491292 c.510G>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 0.6 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491296 p.Val172Ile missense_variant 0.62 pretomanid
delamanid
clofazimine
fgd1 491319 c.537G>C synonymous_variant 0.65 pretomanid
delamanid
clofazimine
fgd1 491331 c.549G>A synonymous_variant 0.69 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>C synonymous_variant 0.58 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fgd1 491367 c.585G>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fgd1 491388 c.606C>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fgd1 491591 p.Lys270Met missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine Not assoc w R
mshA 575641 c.294A>G synonymous_variant 0.42 isoniazid
ethionamide
mshA 575648 p.Val101Gln missense_variant 0.42 isoniazid
ethionamide
mshA 575658 p.Ala104Val missense_variant 0.43 isoniazid
ethionamide
mshA 575665 c.318G>C synonymous_variant 0.43 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575669 p.Leu108Val missense_variant 0.46 isoniazid
ethionamide
mshA 575689 c.342G>C synonymous_variant 0.46 isoniazid
ethionamide
mshA 575695 c.348C>G synonymous_variant 0.46 isoniazid Not assoc w R - Interim
ethionamide
mshA 575704 c.357T>C synonymous_variant 0.46 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 0.43 isoniazid
ethionamide
mshA 575713 c.366G>A synonymous_variant 0.46 isoniazid
ethionamide
mshA 575719 c.372C>T synonymous_variant 0.44 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.44 isoniazid
ethionamide
mshA 575737 c.390T>C synonymous_variant 0.44 isoniazid
ethionamide
mshA 575746 c.399C>G synonymous_variant 0.46 isoniazid
ethionamide
mshA 575767 c.420G>A synonymous_variant 0.46 isoniazid
ethionamide
mshA 575771 p.Val142Ser missense_variant 0.44 isoniazid
ethionamide
mshA 575779 c.432A>G synonymous_variant 0.44 isoniazid
ethionamide
mshA 575821 c.474G>C synonymous_variant 0.46 isoniazid
ethionamide
mshA 575824 c.477T>G synonymous_variant 0.46 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 0.42 isoniazid
ethionamide
mshA 575878 c.531A>G synonymous_variant 0.5 isoniazid
ethionamide
ccsA 619507 c.-384A>G upstream_gene_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 619531 c.-360T>G upstream_gene_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 619535 c.-356_-355delCAinsGC upstream_gene_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 619552 c.-339A>G upstream_gene_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 619555 c.-336C>G upstream_gene_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 619558 c.-333G>C upstream_gene_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 619564 c.-327C>G upstream_gene_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 619570 c.-321G>C upstream_gene_variant 0.42 kanamycin
capreomycin
amikacin
ccsA 619574 c.-317G>A upstream_gene_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 619579 c.-312G>C upstream_gene_variant 0.34 kanamycin
capreomycin
amikacin
ccsA 619591 c.-300G>C upstream_gene_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 619627 c.-264C>G upstream_gene_variant 0.37 kanamycin
capreomycin
amikacin
ccsA 619634 c.-257T>A upstream_gene_variant 0.36 kanamycin
capreomycin
amikacin
ccsA 619648 c.-243C>G upstream_gene_variant 0.28 kanamycin
capreomycin
amikacin
ccsA 620245 c.355T>C synonymous_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 620249 p.Ser120Cys missense_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 0.58 kanamycin
capreomycin
amikacin
ccsA 620257 p.Ile123Val missense_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 620265 c.375C>G synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620269 p.Val127Ile missense_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620283 c.393T>C synonymous_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620284 p.Ala132Pro missense_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620288 p.Arg133Gln missense_variant 0.67 kanamycin
capreomycin
amikacin
ccsA 620295 c.405G>C synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620307 c.417C>G synonymous_variant 0.63 kanamycin
capreomycin
amikacin
ccsA 620317 p.Val143Leu missense_variant 0.6 kanamycin
capreomycin
amikacin
ccsA 620322 c.432G>C synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620340 c.450C>G synonymous_variant 0.57 kanamycin
capreomycin
amikacin
ccsA 620349 c.459A>G synonymous_variant 0.55 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Thr missense_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620373 c.483C>G synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 0.52 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 0.48 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 0.48 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620433 c.543C>G synonymous_variant 0.43 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 0.43 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620646 c.756G>A synonymous_variant 0.39 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 0.45 kanamycin
capreomycin
amikacin
ccsA 620703 c.813G>C synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620710 p.Val274Ile missense_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620718 c.828G>C synonymous_variant 0.3 kanamycin
capreomycin
amikacin
ccsA 620721 c.831G>C synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620734 c.844C>A synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 0.32 kanamycin
capreomycin
amikacin
ccsA 620745 c.855G>C synonymous_variant 0.33 kanamycin
capreomycin
amikacin
ccsA 620748 c.858T>A synonymous_variant 0.41 kanamycin
capreomycin
amikacin
ccsA 620778 c.888T>C synonymous_variant 0.64 kanamycin
capreomycin
amikacin
ccsA 620784 c.894C>G synonymous_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620787 c.897C>G synonymous_variant 0.54 kanamycin
capreomycin
amikacin
ccsA 620809 c.919C>T synonymous_variant 0.58 kanamycin
capreomycin
amikacin
Rv0565c 657269 p.Ser68Pro missense_variant 0.84 ethionamide Uncertain significance
Rv0565c 657602 c.-132C>G upstream_gene_variant 0.25 ethionamide
Rv0565c 657632 c.-162G>A upstream_gene_variant 0.28 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.28 ethionamide
Rv0565c 657641 c.-171C>G upstream_gene_variant 0.28 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.39 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.45 ethionamide
Rv0565c 657686 c.-216C>G upstream_gene_variant 0.47 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.48 ethionamide
Rv0565c 657701 c.-231C>G upstream_gene_variant 0.57 ethionamide
Rv0565c 657719 c.-249C>G upstream_gene_variant 0.57 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.56 ethionamide
hadA 731681 c.-249A>C upstream_gene_variant 0.5 isoniazid
hadA 731687 c.-243_-242insCACGGATTTTTT upstream_gene_variant 0.47 isoniazid
hadA 731690 c.-240A>C upstream_gene_variant 0.47 isoniazid
hadA 731693 c.-237C>A upstream_gene_variant 0.5 isoniazid
hadA 731696 c.-233_-232delTT upstream_gene_variant 0.5 isoniazid
hadA 731701 c.-229A>G upstream_gene_variant 0.5 isoniazid
hadA 731702 c.-228G>C upstream_gene_variant 0.5 isoniazid
hadA 731708 c.-222G>C upstream_gene_variant 0.5 isoniazid
hadA 731710 c.-220A>T upstream_gene_variant 0.54 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.54 isoniazid
hadA 731732 c.-198G>A upstream_gene_variant 0.57 isoniazid
hadA 731741 c.-189G>A upstream_gene_variant 0.57 isoniazid
hadA 731747 c.-183T>C upstream_gene_variant 0.5 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 0.57 isoniazid
hadA 732329 p.Leu134Val missense_variant 0.47 isoniazid Uncertain significance
hadA 732337 c.408G>A synonymous_variant 0.47 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.56 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.59 isoniazid
hadA 732389 p.Ser154Thr missense_variant 0.6 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.6 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.6 isoniazid
nusG 734407 p.Val52Ile missense_variant 0.42 rifampicin
nusG 734421 c.168A>G synonymous_variant 0.4 rifampicin
nusG 734424 c.171G>A synonymous_variant 0.4 rifampicin
nusG 734442 c.189G>A synonymous_variant 0.45 rifampicin
nusG 734457 c.204C>G synonymous_variant 0.43 rifampicin
nusG 734472 c.219T>C synonymous_variant 0.41 rifampicin
nusG 734475 c.222T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
nusG 734481 c.228C>G synonymous_variant 0.48 rifampicin
nusG 734499 c.246G>C synonymous_variant 0.48 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.62 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
nusG 734595 c.342C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
nusG 734596 c.343T>C synonymous_variant 0.58 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.56 rifampicin
nusG 734625 c.372T>C synonymous_variant 0.52 rifampicin
nusG 734634 c.381G>C synonymous_variant 0.54 rifampicin
nusG 734643 c.390G>C synonymous_variant 0.56 rifampicin
nusG 734652 c.399T>C synonymous_variant 0.56 rifampicin
nusG 734655 c.402G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
nusG 734658 c.405A>G synonymous_variant 0.54 rifampicin Not assoc w R
nusG 734661 c.408A>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
nusG 734664 c.411T>G synonymous_variant 0.58 rifampicin
nusG 734673 c.420A>G synonymous_variant 0.58 rifampicin
nusG 734679 c.426C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
nusG 734680 p.Ala143Ser missense_variant 0.54 rifampicin
nusG 734703 c.450T>C synonymous_variant 0.6 rifampicin
nusG 734709 c.456T>G synonymous_variant 0.58 rifampicin
nusG 734715 c.462G>C synonymous_variant 0.58 rifampicin
nusG 734718 c.465G>C synonymous_variant 0.57 rifampicin
nusG 734719 p.Ser156Ala missense_variant 0.57 rifampicin
nusG 734726 p.Arg158Lys missense_variant 0.54 rifampicin
nusG 734732 p.Ala160Val missense_variant 0.48 rifampicin
nusG 734754 c.501G>C synonymous_variant 0.5 rifampicin
nusG 734757 c.504T>G synonymous_variant 0.53 rifampicin Not assoc w R - Interim
nusG 734778 c.525G>C synonymous_variant 0.48 rifampicin
nusG 734781 c.528A>G synonymous_variant 0.44 rifampicin
nusG 734792 p.Val180Ala missense_variant 0.44 rifampicin
nusG 734794 p.Val181Ile missense_variant 0.42 rifampicin Uncertain significance
nusG 734820 c.567A>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 0.36 rifampicin
nusG 734829 c.576C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
nusG 734832 c.579C>G synonymous_variant 0.34 rifampicin
nusG 734841 c.588G>A synonymous_variant 0.31 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.31 rifampicin
nusG 734853 c.600A>C synonymous_variant 0.27 rifampicin
nusG 734854 c.601T>C synonymous_variant 0.27 rifampicin
rpoB 760101 c.295T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760106 c.300G>T synonymous_variant 0.32 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.32 rifampicin
rpoB 760115 c.309C>T synonymous_variant 0.68 rifampicin Not assoc w R
rpoB 760118 c.312T>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.42 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.44 rifampicin
rpoB 760181 c.375T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760223 c.417T>C synonymous_variant 0.72 rifampicin
rpoB 760235 c.429T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760253 c.447T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.8 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.74 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.75 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.73 rifampicin
rpoB 760340 c.534G>C synonymous_variant 0.74 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 0.71 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.67 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.6 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.51 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.53 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.7 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.62 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>G synonymous_variant 0.62 rifampicin
rpoB 760721 c.915C>G synonymous_variant 0.6 rifampicin
rpoB 760724 c.918T>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 760751 c.945G>C synonymous_variant 0.57 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.52 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.51 rifampicin
rpoB 760763 c.957C>T synonymous_variant 0.51 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.5 rifampicin
rpoB 760775 c.969G>C synonymous_variant 0.5 rifampicin
rpoB 760776 c.970_972delTCGinsAGC synonymous_variant 0.5 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.54 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.55 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.53 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.53 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 760845 p.Thr347Pro missense_variant 0.62 rifampicin
rpoB 760859 c.1053T>C synonymous_variant 0.64 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 760869 p.Val355Ile missense_variant 0.65 rifampicin Uncertain significance
rpoB 760886 c.1080A>G synonymous_variant 0.69 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.75 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.75 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760934 c.1128C>T synonymous_variant 0.76 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoB 760970 c.1164G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 760982 c.1176G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 0.8 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.88 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>A synonymous_variant 0.88 rifampicin
rpoB 761057 c.1251G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.84 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.84 rifampicin
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.8 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.8 rifampicin
rpoB 761171 c.1365C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761183 c.1377T>G synonymous_variant 0.79 rifampicin
rpoB 761189 c.1383T>G synonymous_variant 0.82 rifampicin
rpoB 761222 c.1416G>C synonymous_variant 0.81 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761297 c.1491C>T synonymous_variant 0.77 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoB 761360 c.1554T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.8 rifampicin
rpoB 761373 p.Val523His missense_variant 0.83 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.71 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.73 rifampicin
rpoB 761437 p.Ala544Asp missense_variant 0.72 rifampicin
rpoB 761439 p.Asp545Lys missense_variant 0.72 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.72 rifampicin
rpoB 761447 c.1641C>G synonymous_variant 0.69 rifampicin
rpoB 761452 p.Val549Ala missense_variant 0.69 rifampicin
rpoB 761457 p.Pro551Ala missense_variant 0.69 rifampicin
rpoB 761462 c.1656C>G synonymous_variant 0.7 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.62 rifampicin
rpoB 761510 c.1704T>C synonymous_variant 0.61 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.59 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.49 rifampicin
rpoB 761612 c.1806G>C synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 0.41 rifampicin
rpoB 761657 c.1851C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761675 c.1869G>C synonymous_variant 0.44 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.43 rifampicin
rpoB 761723 c.1917_1919delAGAinsG frameshift_variant&synonymous_variant 0.41 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.44 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 0.49 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.47 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.48 rifampicin
rpoB 761768 c.1962G>T synonymous_variant 0.48 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.47 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.46 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.45 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.48 rifampicin
rpoB 761815 p.Ala670Glu missense_variant 0.49 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.52 rifampicin
rpoB 761847 p.Cys681Ser missense_variant 0.53 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.55 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.52 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>G synonymous_variant 0.57 rifampicin
rpoB 761882 c.2076C>G synonymous_variant 0.55 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.56 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.58 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.51 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.51 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.5 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.5 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.5 rifampicin
rpoB 761924 c.2118G>A synonymous_variant 0.5 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoB 761969 c.2163G>A synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 0.57 rifampicin
rpoB 762008 c.2202C>G synonymous_variant 0.57 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.58 rifampicin
rpoB 762017 c.2211A>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.57 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.6 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.58 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.58 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.59 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>G synonymous_variant 0.63 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 762266 c.2460T>C synonymous_variant 0.7 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.61 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.61 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.57 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.55 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 0.53 rifampicin
rpoC 762380 c.-990T>G upstream_gene_variant 0.55 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.52 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.52 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.54 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.54 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.5 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.49 rifampicin Not assoc w R - Interim
rpoC 762443 c.-927G>T upstream_gene_variant 0.43 rifampicin
rpoB 762470 c.2664G>C synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762489 p.Val895Gln missense_variant 0.32 rifampicin
rpoC 762509 c.-861T>G upstream_gene_variant 0.28 rifampicin
rpoC 762521 c.-849C>G upstream_gene_variant 0.3 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.29 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.3 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.3 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.28 rifampicin
rpoB 762782 c.2976T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoB 762785 p.Asp993Glu missense_variant 0.3 rifampicin Uncertain significance
rpoB 762788 c.2982G>C synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762789 p.Leu995Met missense_variant 0.3 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 0.33 rifampicin
rpoB 762799 p.Ala998Gly missense_variant 0.33 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 0.35 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.33 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.32 rifampicin Not assoc w R - Interim
rpoB 762830 c.3024C>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoB 762831 c.3025_3026delAGinsTC synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 762836 c.-534C>G upstream_gene_variant 0.36 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.71 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 0.79 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.52 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.48 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.4 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.37 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 0.37 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.37 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763226 c.-144A>G upstream_gene_variant 0.46 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoB 763268 c.3462C>G synonymous_variant 0.48 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.4 rifampicin
rpoC 763304 c.-66_-63delAAGTinsGTCC upstream_gene_variant 0.35 rifampicin
rpoB 763316 c.3510T>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 763319 c.-51T>G upstream_gene_variant 0.36 rifampicin
rpoC 763322 c.-48G>T upstream_gene_variant 0.35 rifampicin
rpoC 763325 c.-44_-37delAGCTGTCG upstream_gene_variant 0.36 rifampicin
rpoC 763335 c.-35A>C upstream_gene_variant 0.35 rifampicin
rpoC 763338 c.-32A>C upstream_gene_variant 0.33 rifampicin
rpoC 763340 c.-30_-29insTTTCACTA upstream_gene_variant 0.32 rifampicin
rpoC 763343 c.-27T>C upstream_gene_variant 0.32 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 0.32 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 0.32 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 0.44 rifampicin
rpoC 763411 c.42T>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.42 rifampicin
rpoC 763441 c.72C>G synonymous_variant 0.42 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.42 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 0.4 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.39 rifampicin Not assoc w R - Interim
rpoC 763528 c.159G>A synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.51 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.66 rifampicin
rpoC 763642 c.273G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763658 c.289_291delCTTinsTTG synonymous_variant 0.67 rifampicin
rpoC 763675 c.306C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>A synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 0.67 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.69 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.68 rifampicin
rpoC 763735 c.366G>C synonymous_variant 0.67 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.72 rifampicin
rpoC 763765 c.396T>C synonymous_variant 0.72 rifampicin
rpoC 763768 c.399C>G synonymous_variant 0.72 rifampicin
rpoC 763780 c.411C>G synonymous_variant 0.75 rifampicin
rpoC 763783 c.414G>C synonymous_variant 0.75 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.8 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 763819 c.450G>C synonymous_variant 0.8 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.79 rifampicin
rpoC 763835 p.Ala156Met missense_variant 0.77 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.81 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.8 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.81 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.81 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.82 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.8 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.82 rifampicin
rpoC 763919 c.550C>T synonymous_variant 0.8 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763945 c.576T>C synonymous_variant 0.81 rifampicin
rpoC 763960 c.591T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 763967 p.Gly200Ser missense_variant 0.83 rifampicin
rpoC 763978 c.609C>G synonymous_variant 0.79 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.77 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.83 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.75 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 0.69 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.68 rifampicin
rpoC 764059 c.690G>C synonymous_variant 0.66 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.66 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 764131 c.762T>C synonymous_variant 0.71 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.72 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Gln missense_variant 0.68 rifampicin
rpoC 764203 c.834G>T synonymous_variant 0.65 rifampicin
rpoC 764206 c.837T>C synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764257 c.888G>C synonymous_variant 0.66 rifampicin
rpoC 764263 c.894G>A synonymous_variant 0.39 rifampicin Not assoc w R
rpoC 764266 c.897T>C synonymous_variant 0.63 rifampicin
rpoC 764269 c.900G>C synonymous_variant 0.68 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764282 c.913_915delTCGinsAGC synonymous_variant 0.63 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.66 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.65 rifampicin
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.59 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.61 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.59 rifampicin
rpoC 764455 c.1086G>C synonymous_variant 0.59 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.61 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764521 c.1152T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>C synonymous_variant 0.69 rifampicin
rpoC 764539 c.1170C>G synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764560 c.1191T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 764573 c.1204_1206delCTTinsTTG synonymous_variant 0.63 rifampicin
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.58 rifampicin
rpoC 764581 c.1212T>C synonymous_variant 0.61 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 764714 c.1345C>T synonymous_variant 0.65 rifampicin
rpoC 764720 c.1351C>T synonymous_variant 0.68 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.43 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.39 rifampicin Not assoc w R
rpoC 764812 c.1443C>G synonymous_variant 0.38 rifampicin
rpoC 764815 c.1446A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.41 rifampicin Not assoc w R - Interim
rpoC 764830 c.1461C>G synonymous_variant 0.4 rifampicin
rpoC 764858 c.1489T>C synonymous_variant 0.36 rifampicin Not assoc w R - Interim
rpoC 764872 c.1503A>G synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 764893 c.1524T>C synonymous_variant 0.33 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.35 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>A synonymous_variant 0.34 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.29 rifampicin Not assoc w R - Interim
rpoC 764995 c.1626C>G synonymous_variant 0.32 rifampicin Not assoc w R
rpoC 765007 c.1638T>G synonymous_variant 0.3 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765022 c.1653G>C synonymous_variant 0.28 rifampicin
rpoC 765034 c.1665T>C synonymous_variant 0.31 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.31 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.28 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 0.27 rifampicin Not assoc w R - Interim
rpoC 765150 p.Gly594Glu missense_variant 0.88 rifampicin Not assoc w R
rpoC 765298 c.1929G>C synonymous_variant 0.57 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.57 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765326 p.His653Ala missense_variant 0.68 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.68 rifampicin Uncertain significance
rpoC 765349 c.1980T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765352 c.1983G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.69 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.69 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 0.66 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.68 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765451 c.2082C>G synonymous_variant 0.63 rifampicin
rpoC 765452 p.Ala695Ser missense_variant 0.62 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.62 rifampicin Not assoc w R - Interim
rpoC 765499 c.2130C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 765541 c.2172C>G synonymous_variant 0.59 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.56 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.58 rifampicin
rpoC 765559 c.2190G>C synonymous_variant 0.58 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.56 rifampicin
rpoC 765583 c.2214G>T synonymous_variant 0.57 rifampicin
rpoC 765613 p.His748Gln missense_variant 0.58 rifampicin
rpoC 765625 c.2256C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 765628 c.2259G>C synonymous_variant 0.6 rifampicin Not assoc w R - Interim
rpoC 765631 p.Asp754Glu missense_variant 0.64 rifampicin
rpoC 765658 c.2289C>T synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765700 c.2331T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765734 c.2365T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765751 c.2382C>G synonymous_variant 0.81 rifampicin
rpoC 765753 p.Asp795Ala missense_variant 0.82 rifampicin Uncertain significance
rpoC 765772 c.2403C>G synonymous_variant 0.84 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.84 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.79 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.72 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.72 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765928 c.2559C>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765967 c.2598C>T synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765970 c.2601C>T synonymous_variant 0.7 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 765985 c.2616C>T synonymous_variant 0.66 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.64 rifampicin Not assoc w R - Interim
rpoC 766009 c.2640G>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.58 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 0.58 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 0.51 rifampicin
rpoC 766054 c.2685C>G synonymous_variant 0.47 rifampicin
rpoC 766069 c.2700G>A synonymous_variant 0.44 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.42 rifampicin
rpoC 766096 c.2727G>C synonymous_variant 0.47 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.44 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.39 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.38 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.38 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766185 p.Glu939Ala missense_variant 0.24 rifampicin
rpoC 766189 c.2820T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 766192 c.2823T>C synonymous_variant 0.24 rifampicin Not assoc w R - Interim
rpoC 766193 p.Gln942Glu missense_variant 0.24 rifampicin
rpoC 766204 c.2835C>T synonymous_variant 0.21 rifampicin
rpoC 766234 c.2865T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 766237 c.2868T>C synonymous_variant 0.25 rifampicin Not assoc w R - Interim
rpoC 766244 p.Gln959Ser missense_variant 0.24 rifampicin
rpoC 766258 c.2889T>C synonymous_variant 0.3 rifampicin
rpoC 766270 c.2901G>C synonymous_variant 0.29 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.29 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.29 rifampicin
rpoC 766279 c.2910C>G synonymous_variant 0.28 rifampicin
rpoC 766280 p.Ser971Gly missense_variant 0.28 rifampicin
rpoC 766309 c.2940G>C synonymous_variant 0.35 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>G synonymous_variant 0.35 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.35 rifampicin
rpoC 766327 c.2958C>G synonymous_variant 0.41 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.44 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.46 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.48 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.48 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.5 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.5 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.53 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.59 rifampicin
rpoC 766444 c.3075C>G synonymous_variant 0.59 rifampicin
rpoC 766447 c.3078T>C synonymous_variant 0.61 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 0.64 rifampicin
rpoC 766484 p.Val1039Ile missense_variant 0.62 rifampicin Uncertain significance
rpoC 766492 c.3123T>C synonymous_variant 0.64 rifampicin
rpoC 766495 c.3126C>T synonymous_variant 0.66 rifampicin Not assoc w R - Interim
rpoC 766528 c.3159T>G synonymous_variant 0.76 rifampicin
rpoC 766543 c.3174C>T synonymous_variant 0.79 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.77 rifampicin
rpoC 766583 p.Gly1072Ser missense_variant 0.76 rifampicin
rpoC 766591 c.3222A>G synonymous_variant 0.76 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.76 rifampicin
rpoC 766597 c.3228C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.76 rifampicin
rpoC 766630 c.3261G>C synonymous_variant 0.77 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.74 rifampicin
rpoC 766651 c.3282T>C synonymous_variant 0.71 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.69 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.64 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 0.74 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.74 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 766769 c.3400C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.77 rifampicin
rpoC 766801 c.3432C>G synonymous_variant 0.77 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.71 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.71 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.71 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.74 rifampicin
rpoC 766933 c.3564A>G synonymous_variant 0.76 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 766972 c.3603G>C synonymous_variant 0.74 rifampicin
rpoC 766978 c.3609C>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.74 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.74 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 0.72 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.75 rifampicin
rpoC 767074 c.3705T>C synonymous_variant 0.76 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>G synonymous_variant 0.78 rifampicin
rpoC 767158 c.3789T>G synonymous_variant 0.71 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.7 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 0.57 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.55 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.52 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.44 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.47 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.47 rifampicin
rpoC 767275 c.3906T>C synonymous_variant 0.5 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.5 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
mmpL5 775975 c.2506T>C synonymous_variant 0.44 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 0.42 bedaquiline
clofazimine
mmpL5 775997 c.2484T>C synonymous_variant 0.42 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.47 bedaquiline
clofazimine
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781631 c.72G>C synonymous_variant 0.36 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.46 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.47 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.45 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.46 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.48 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.5 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.53 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.54 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.54 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.55 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.6 streptomycin
rpsL 781841 c.282C>G synonymous_variant 0.59 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.53 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.52 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.51 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.49 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.49 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.51 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.54 streptomycin Uncertain significance
rplC 800200 c.-609C>G upstream_gene_variant 1.0 linezolid
rplC 800516 c.-293G>T upstream_gene_variant 0.3 linezolid
rplC 800537 c.-272C>T upstream_gene_variant 0.38 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.38 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.38 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.41 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 0.48 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.59 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.59 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 0.68 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.68 linezolid
rplC 800690 c.-119C>T upstream_gene_variant 0.7 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.7 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.73 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.71 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 0.73 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.71 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 0.71 linezolid
rplC 800747 c.-62C>G upstream_gene_variant 0.65 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 0.61 linezolid
rplC 800794 c.-15_-9delAGATTGGinsGAGTT upstream_gene_variant 0.61 linezolid
rplC 800814 c.6A>G synonymous_variant 0.59 linezolid
rplC 800817 c.9A>T synonymous_variant 0.59 linezolid
rplC 800844 c.36T>C synonymous_variant 0.5 linezolid
rplC 800865 c.57A>G synonymous_variant 0.52 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.52 linezolid
rplC 800874 c.66A>G synonymous_variant 0.56 linezolid
rplC 800877 c.69A>C synonymous_variant 0.54 linezolid
rplC 800880 c.72A>G synonymous_variant 0.54 linezolid
rplC 800889 c.81C>G synonymous_variant 0.59 linezolid
rplC 800907 c.99C>G synonymous_variant 0.52 linezolid
rplC 800916 c.108A>G synonymous_variant 0.54 linezolid
rplC 800937 c.129A>G synonymous_variant 0.48 linezolid
rplC 800939 p.Arg44Gln missense_variant 0.46 linezolid
rplC 800946 c.138T>C synonymous_variant 0.46 linezolid
rplC 800949 c.141T>C synonymous_variant 0.46 linezolid
rplC 800955 c.147C>G synonymous_variant 0.48 linezolid
rplC 800967 c.159C>G synonymous_variant 0.47 linezolid
rplC 800970 c.162T>C synonymous_variant 0.45 linezolid Not assoc w R - Interim
rplC 800982 c.174C>T synonymous_variant 0.41 linezolid
rplC 800985 c.177A>G synonymous_variant 0.41 linezolid
rplC 800994 c.186C>G synonymous_variant 0.36 linezolid
rplC 801004 p.Leu66Val missense_variant 0.35 linezolid
rplC 801009 c.201A>C synonymous_variant 0.35 linezolid
rplC 801012 c.204T>C synonymous_variant 0.37 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.35 linezolid
rplC 801024 c.216C>G synonymous_variant 0.35 linezolid
rplC 801027 c.219C>G synonymous_variant 0.32 linezolid
rplC 801031 p.Val75Ile missense_variant 0.31 linezolid
rplC 801039 c.231A>G synonymous_variant 0.3 linezolid
rplC 801045 c.237A>C synonymous_variant 0.3 linezolid
rplC 801047 p.Tyr80Phe missense_variant 0.3 linezolid
rplC 801054 c.246G>C synonymous_variant 0.3 linezolid
rplC 801070 p.Asp88Asn missense_variant 0.27 linezolid
rplC 801085 p.Thr93Ala missense_variant 0.25 linezolid Uncertain significance
rplC 801090 c.282G>A synonymous_variant 0.29 linezolid
rplC 801099 c.291T>C synonymous_variant 0.28 linezolid
rplC 801102 c.294G>C synonymous_variant 0.28 linezolid
rplC 801105 c.297A>G synonymous_variant 0.29 linezolid
rplC 801109 c.301T>C synonymous_variant 0.29 linezolid Not assoc w R - Interim
rplC 801114 c.306C>G synonymous_variant 0.31 linezolid
rplC 801127 p.Ala107Thr missense_variant 0.32 linezolid
rplC 801132 c.324T>C synonymous_variant 0.33 linezolid
rplC 801147 c.339T>C synonymous_variant 0.4 linezolid
rplC 801150 c.342G>C synonymous_variant 0.4 linezolid
rplC 801153 c.345G>C synonymous_variant 0.4 linezolid
rplC 801156 c.348T>A synonymous_variant 0.4 linezolid
rplC 801171 c.363A>G synonymous_variant 0.46 linezolid
rplC 801174 c.366T>C synonymous_variant 0.47 linezolid
rplC 801222 c.414T>C synonymous_variant 0.48 linezolid
rplC 801228 c.420T>C synonymous_variant 0.5 linezolid
rplC 801246 c.438C>G synonymous_variant 0.54 linezolid
rplC 801249 c.441T>G synonymous_variant 0.52 linezolid
rplC 801255 c.447C>T synonymous_variant 0.55 linezolid
rplC 801267 c.459A>T synonymous_variant 0.45 linezolid
rplC 801348 c.540T>G synonymous_variant 0.33 linezolid
rplC 801357 c.549T>C synonymous_variant 0.34 linezolid
rplC 801367 p.Ala187Thr missense_variant 0.35 linezolid
rplC 801396 c.588T>C synonymous_variant 0.38 linezolid
rplC 801402 c.594T>C synonymous_variant 0.38 linezolid
rplC 801405 c.597T>C synonymous_variant 0.35 linezolid
rplC 801417 c.609T>C synonymous_variant 0.32 linezolid
rplC 801423 c.615G>C synonymous_variant 0.31 linezolid
rplC 801438 c.630T>C synonymous_variant 0.3 linezolid
rplC 801442 p.Ile212Val missense_variant 0.26 linezolid
rplC 801461 c.653G>A splice_region_variant&stop_retained_variant 0.23 linezolid
Rv1129c 1253097 p.Ser480Pro missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
isoniazid Uncertain significance
rifampicin Uncertain significance
fbiC 1303464 c.534A>G synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303470 c.540T>G synonymous_variant 0.32 pretomanid
delamanid
clofazimine
fbiC 1303476 c.546G>C synonymous_variant 0.31 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303480 p.Gln184Glu missense_variant 0.31 pretomanid
delamanid
clofazimine
fbiC 1303509 c.579G>C synonymous_variant 0.33 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>C synonymous_variant 0.36 pretomanid
delamanid
clofazimine
fbiC 1303534 p.Ser202Ala missense_variant 0.37 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1303560 c.630G>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1303575 c.645G>C synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1303590 c.660A>G synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303605 c.675C>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303608 c.678G>A synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303611 c.681G>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303614 c.684C>T synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303617 c.687C>G synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1303638 c.708A>G synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303659 c.729T>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1303660 p.Val244Thr missense_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1303674 c.744C>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303686 c.756C>G synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303695 c.765T>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303701 c.771C>G synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1303708 c.778T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303716 c.786C>T synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1303728 c.798G>A synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1303731 c.801A>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303732 p.Ser268Ala missense_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303737 c.807G>A synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1303746 c.816T>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303749 c.819G>C synonymous_variant 0.47 pretomanid
delamanid
clofazimine
fbiC 1303752 c.822A>G synonymous_variant 0.47 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1303755 c.825T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1303785 c.855G>C synonymous_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1303789 p.Ile287Val missense_variant 0.51 pretomanid
delamanid
clofazimine
fbiC 1303818 c.888C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1303836 c.906G>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303845 c.915C>G synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303846 p.Phe306Val missense_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1303854 c.924T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303860 c.930A>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1303881 c.951G>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303884 c.954T>G synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1303911 c.981G>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1303914 c.984C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303920 c.990C>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303923 c.993C>T synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1303929 c.999G>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1303947 c.1017T>C synonymous_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303948 p.Gly340Arg missense_variant 0.56 pretomanid
delamanid
clofazimine
fbiC 1303969 p.Val347Ile missense_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1303973 p.Gly348Ala missense_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1303981 p.Val351Ile missense_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1303995 c.1065C>T synonymous_variant 0.62 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304001 c.1071C>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304008 c.1078T>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304034 c.1104A>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304040 c.1110C>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304046 c.1116C>G synonymous_variant 0.55 pretomanid
delamanid
clofazimine
fbiC 1304049 c.1119T>G synonymous_variant 0.54 pretomanid
delamanid
clofazimine
fbiC 1304058 c.1128G>A synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304059 c.1129C>T synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304064 c.1134G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304067 c.1137G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304080 p.Ala384Ser missense_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304091 p.Asp387Glu missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304092 p.Met388Leu missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304097 c.1167G>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304115 c.1185A>G synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304127 c.1197A>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304565 c.1635C>G synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304568 c.1638T>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1304574 c.1644C>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 0.5 pretomanid
delamanid
clofazimine
fbiC 1304628 c.1698G>C synonymous_variant 0.52 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304658 c.1728C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>T synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Glu missense_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304691 c.1761G>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304703 c.1773C>G synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>C synonymous_variant 0.59 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.6 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.63 pretomanid
delamanid
clofazimine
fbiC 1304748 c.1818T>C synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304754 c.1824G>A synonymous_variant 0.61 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.6 pretomanid
delamanid
clofazimine
fbiC 1304784 c.1854T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304787 c.1857T>C synonymous_variant 0.64 pretomanid
delamanid
clofazimine
fbiC 1304790 c.1860C>G synonymous_variant 0.62 pretomanid
delamanid
clofazimine
fbiC 1304808 c.1878C>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304811 c.1881C>G synonymous_variant 0.58 pretomanid
delamanid
clofazimine
fbiC 1304817 c.1887T>C synonymous_variant 0.57 pretomanid
delamanid
clofazimine
fbiC 1304829 c.1899T>C synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304832 c.1902C>G synonymous_variant 0.5 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 0.5 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.48 pretomanid
delamanid
clofazimine
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304877 c.1947T>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304878 c.1948_1950delCGCinsAGG synonymous_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304893 p.Gly655Ser missense_variant 0.45 pretomanid
delamanid
clofazimine
fbiC 1304916 c.1986T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304925 c.1995G>C synonymous_variant 0.44 pretomanid
delamanid
clofazimine
fbiC 1304928 c.1998T>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304934 c.2004C>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304937 c.2007G>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304940 c.2010A>G synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304946 c.2016G>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304958 c.2028T>G synonymous_variant 0.49 pretomanid
delamanid
clofazimine
fbiC 1304961 c.2031C>T synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fbiC 1304991 c.2061G>C synonymous_variant 0.43 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1304995 c.2065T>C synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1305006 c.2076A>G synonymous_variant 0.41 pretomanid
delamanid
clofazimine
fbiC 1305012 c.2082G>C synonymous_variant 0.39 pretomanid
delamanid
clofazimine
fbiC 1305015 c.2085G>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1305021 c.2091C>A synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1305027 c.2097G>A synonymous_variant 0.3 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>G synonymous_variant 0.28 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 0.27 pretomanid
delamanid
clofazimine
fbiC 1305126 c.2196T>C synonymous_variant 0.36 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1305135 c.2205C>T synonymous_variant 0.35 pretomanid
delamanid
clofazimine
fbiC 1305276 c.2346G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1305279 p.His783Gln missense_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1305282 c.2352T>C synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1305297 c.2367G>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1305300 c.2370A>G synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1305303 c.2373T>C synonymous_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1305306 c.2376A>T synonymous_variant 0.38 pretomanid
delamanid
clofazimine
fbiC 1305311 p.Arg794Gln missense_variant 0.4 pretomanid
delamanid
clofazimine
fbiC 1305331 p.Glu801Asn missense_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1305336 c.2406T>C synonymous_variant 0.42 pretomanid
delamanid
clofazimine
fbiC 1305381 c.2451G>C synonymous_variant 0.32 pretomanid
delamanid
clofazimine
sigE 1364676 c.264C>G synonymous_variant 0.35 pyrazinamide
sigE 1364679 c.267T>C synonymous_variant 0.35 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.41 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.48 pyrazinamide
sigE 1364718 c.306C>T synonymous_variant 0.48 pyrazinamide
sigE 1364727 c.315C>T synonymous_variant 0.5 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.54 pyrazinamide
sigE 1364748 c.336G>C synonymous_variant 0.54 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.6 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.62 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 0.66 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.7 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.71 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.7 pyrazinamide
sigE 1364835 c.423C>G synonymous_variant 0.73 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.73 pyrazinamide
sigE 1364862 c.450C>G synonymous_variant 0.76 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.76 pyrazinamide
sigE 1364866 p.Ala152Ser missense_variant 0.76 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.7 pyrazinamide
sigE 1364904 p.Asp164Glu missense_variant 0.69 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.54 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 0.52 pyrazinamide
sigE 1364934 c.522G>A synonymous_variant 0.52 pyrazinamide
sigE 1364935 p.Gln175Glu missense_variant 0.52 pyrazinamide
sigE 1364949 c.537C>T synonymous_variant 0.48 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.48 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 0.5 pyrazinamide
sigE 1364961 c.549A>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>C synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
sigE 1364967 c.555C>T synonymous_variant 0.53 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.59 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 0.59 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.59 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.56 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.5 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.53 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.47 pyrazinamide
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.41 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.47 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.47 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.54 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.56 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472044 n.199G>C non_coding_transcript_exon_variant 0.6 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.6 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.65 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.67 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.62 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.64 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.52 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.57 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.54 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.49 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.54 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.52 capreomycin Uncertain significance
linezolid
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1473981 n.324delGinsTT non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.58 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.61 capreomycin Uncertain significance
linezolid
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474104 n.447G>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.634_649delTTTCCTCTCCGGAGGAinsC non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.5 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.5 capreomycin
linezolid
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.64 capreomycin Uncertain significance
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474429 n.772G>C non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474431 n.774_775delGCinsTTTGGG non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474435 n.780_783delGAAT non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.62 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.63 capreomycin
linezolid
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.65 capreomycin Uncertain significance
linezolid
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1474959 n.1302C>T non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474962 n.1306delG non_coding_transcript_exon_variant 0.55 capreomycin
linezolid
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.57 capreomycin
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.53 capreomycin
linezolid
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.54 capreomycin
linezolid
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.61 capreomycin
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.75 capreomycin
linezolid
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.74 capreomycin Uncertain significance
linezolid
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475271 n.1614A>C non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475273 n.1616T>A non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.76 capreomycin
linezolid
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.78 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.74 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.67 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.68 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.74 capreomycin
linezolid Uncertain significance
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.78 capreomycin
linezolid
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.87 capreomycin Uncertain significance
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.7 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.56 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.47 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.47 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.45 capreomycin
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.45 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.48 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.48 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.59 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.59 capreomycin
linezolid
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.58 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.56 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.56 capreomycin
linezolid
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.68 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.73 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.72 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.72 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.63 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.6 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.41 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.38 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.39 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.36 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.29 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.29 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.28 capreomycin
linezolid
inhA 1674368 p.Ala56Glu missense_variant 0.4 isoniazid
ethionamide
inhA 1674379 c.178C>T synonymous_variant 0.43 isoniazid
ethionamide
inhA 1674382 p.Leu61Ile missense_variant 0.41 isoniazid
ethionamide
inhA 1674387 c.186A>G synonymous_variant 0.4 isoniazid
ethionamide
inhA 1674399 c.198A>G synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674415 p.Ala72Asn missense_variant 0.41 isoniazid
ethionamide
inhA 1674419 p.Ser73Thr missense_variant 0.4 isoniazid
ethionamide
inhA 1674421 c.220T>C synonymous_variant 0.4 isoniazid
ethionamide
inhA 1674427 p.Gly76Gln missense_variant 0.36 isoniazid
ethionamide
inhA 1674440 p.Glu80Ala missense_variant 0.38 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674443 p.Ala81Glu missense_variant 0.38 isoniazid
ethionamide
inhA 1674450 c.249G>C synonymous_variant 0.4 isoniazid
ethionamide
inhA 1674452 p.Ala84Glu missense_variant 0.4 isoniazid
ethionamide
inhA 1674480 c.279T>C synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674486 c.285T>C synonymous_variant 0.49 isoniazid
ethionamide
inhA 1674489 c.288G>C synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674507 c.306G>C synonymous_variant 0.5 isoniazid
ethionamide
inhA 1674537 c.336C>G synonymous_variant 0.57 isoniazid
ethionamide
inhA 1674542 p.Ala114Glu missense_variant 0.57 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 0.6 isoniazid
ethionamide
inhA 1674555 c.354G>A synonymous_variant 0.59 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.6 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 0.6 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 0.6 isoniazid
ethionamide
inhA 1674624 c.423A>C synonymous_variant 0.74 isoniazid
ethionamide
inhA 1674627 c.426T>G synonymous_variant 0.74 isoniazid
ethionamide
inhA 1674630 c.429C>G synonymous_variant 0.75 isoniazid
ethionamide
inhA 1674636 c.435C>G synonymous_variant 0.76 isoniazid
ethionamide
inhA 1674654 c.453G>C synonymous_variant 0.79 isoniazid
ethionamide
inhA 1674693 c.492C>G synonymous_variant 0.81 isoniazid
ethionamide
inhA 1674703 c.502T>C synonymous_variant 0.79 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 0.76 isoniazid
ethionamide
inhA 1674741 c.540C>G synonymous_variant 0.73 isoniazid
ethionamide
inhA 1674742 p.Lys181Pro missense_variant 0.71 isoniazid
ethionamide
inhA 1674745 p.Tyr182His missense_variant 0.73 isoniazid Uncertain significance
ethionamide Uncertain significance
inhA 1674750 c.549T>C synonymous_variant 0.73 isoniazid
ethionamide
inhA 1674756 c.555T>C synonymous_variant 0.74 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
inhA 1674771 c.570C>G synonymous_variant 0.75 isoniazid
ethionamide
inhA 1674774 c.573A>G synonymous_variant 0.71 isoniazid
ethionamide
inhA 1674876 c.675C>G synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674879 c.678T>C synonymous_variant 0.62 isoniazid
ethionamide
inhA 1674903 c.702T>C synonymous_variant 0.53 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 0.53 isoniazid
ethionamide
inhA 1674909 c.708G>C synonymous_variant 0.53 isoniazid
ethionamide
inhA 1674915 c.714C>G synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 0.42 isoniazid
ethionamide
inhA 1674957 c.756G>C synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674963 c.762G>C synonymous_variant 0.47 isoniazid
ethionamide
inhA 1674966 c.765T>C synonymous_variant 0.39 isoniazid
ethionamide
inhA 1674967 p.Asp256Thr missense_variant 0.39 isoniazid
ethionamide
rpsA 1833554 p.Thr5Ala missense_variant 0.6 pyrazinamide Uncertain significance
rpsA 1833568 c.27G>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.62 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.61 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.69 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.65 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.65 pyrazinamide
rpsA 1833724 c.183C>G synonymous_variant 0.68 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.69 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 0.71 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.73 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 0.66 pyrazinamide
rpsA 1833790 c.249T>A synonymous_variant 0.66 pyrazinamide
rpsA 1833799 c.258C>G synonymous_variant 0.63 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 0.63 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.63 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.65 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.64 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.61 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.62 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.63 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.62 pyrazinamide
rpsA 1833940 c.399C>G synonymous_variant 0.56 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.55 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.54 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.55 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.6 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.59 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.72 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.73 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 0.71 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.71 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.7 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.71 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.71 pyrazinamide
rpsA 1834201 c.660C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.69 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.7 pyrazinamide
rpsA 1834261 c.720A>C synonymous_variant 0.71 pyrazinamide
rpsA 1834264 c.723G>C synonymous_variant 0.72 pyrazinamide
rpsA 1834297 c.756C>G synonymous_variant 0.76 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.74 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.78 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834435 c.894G>C synonymous_variant 0.76 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.72 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.73 pyrazinamide
rpsA 1834474 c.933C>G synonymous_variant 0.75 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.74 pyrazinamide
rpsA 1834498 c.957C>T synonymous_variant 0.72 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.64 pyrazinamide
rpsA 1834555 c.1014T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834558 c.1017C>G synonymous_variant 0.67 pyrazinamide
rpsA 1834594 c.1053C>T synonymous_variant 0.62 pyrazinamide
rpsA 1834606 c.1065C>G synonymous_variant 0.61 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.62 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.62 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.61 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.61 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 0.65 pyrazinamide
rpsA 1834669 c.1128G>C synonymous_variant 0.63 pyrazinamide
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.62 pyrazinamide
rpsA 1834726 c.1185C>A synonymous_variant 0.68 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.67 pyrazinamide
rpsA 1834733 p.Ala398Pro missense_variant 0.67 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.6 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.56 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.5 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.5 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.47 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 0.69 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 0.67 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.67 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.67 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.67 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.63 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.61 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.61 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.58 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 0.5 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.55 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.47 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2064963 c.-235G>C upstream_gene_variant 0.41 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064972 c.-244T>C upstream_gene_variant 0.39 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064978 c.-250G>C upstream_gene_variant 0.39 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064979 c.-253_-251delGGCinsCGT upstream_gene_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064984 c.-256A>G upstream_gene_variant 0.37 kanamycin
capreomycin
streptomycin
amikacin
bacA 2064993 c.-265T>C upstream_gene_variant 0.45 kanamycin
capreomycin
streptomycin
amikacin
ndh 2101812 p.Ile411Val missense_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2101825 c.1218G>C synonymous_variant 0.31 isoniazid
delamanid
ethionamide
ndh 2101830 p.Ile405Val missense_variant 0.3 isoniazid
delamanid
ethionamide
ndh 2101834 c.1209C>T synonymous_variant 0.3 isoniazid
delamanid Not assoc w R - Interim
ethionamide
ndh 2101838 p.Ala402Val missense_variant 0.31 isoniazid Uncertain significance
delamanid
ethionamide Uncertain significance
ndh 2101872 p.Ile391Phe missense_variant 0.31 isoniazid
delamanid
ethionamide
ndh 2101873 p.Phe390Leu missense_variant 0.31 isoniazid
delamanid
ethionamide
ndh 2101885 c.1158G>A synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2101888 p.Val385Leu missense_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2101894 c.1149T>C synonymous_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2101906 c.1137G>C synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2101915 c.1128T>C synonymous_variant 0.36 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2101918 c.1123_1125delAGGinsCGC synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2101924 c.1119T>G synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2101930 c.1113C>A synonymous_variant 0.4 isoniazid
delamanid
ethionamide
ndh 2101939 c.1104A>C synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2101960 c.1083A>G synonymous_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2101966 c.1077T>G synonymous_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2101972 c.1071G>C synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2101978 p.Asn355Asp missense_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2101988 p.Ala352Gly missense_variant 0.37 isoniazid
delamanid
ethionamide
ndh 2101990 c.1053G>T synonymous_variant 0.31 isoniazid
delamanid
ethionamide
ndh 2102009 p.Ser345Asn missense_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102020 c.1023A>G synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2102023 c.1020G>C synonymous_variant 0.33 isoniazid Not assoc w R - Interim
delamanid
ethionamide
ndh 2102026 c.1017G>C synonymous_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2102050 c.993T>C synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102053 c.990G>C synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102059 c.984T>C synonymous_variant 0.4 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102065 c.978G>C synonymous_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2102068 c.975T>C synonymous_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2102076 p.Met323Leu missense_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102077 c.966T>C synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102083 p.Val320Ile missense_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102092 c.951G>C synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102098 c.945G>C synonymous_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102103 p.Tyr314His missense_variant 0.39 isoniazid
delamanid
ethionamide
ndh 2102104 c.939G>C synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102110 c.933T>C synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102131 p.Gln304Lys missense_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2102140 c.903C>G synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102149 c.894C>T synonymous_variant 0.32 isoniazid Not assoc w R - Interim
delamanid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
ndh 2102158 c.885T>C synonymous_variant 0.32 isoniazid
delamanid
ethionamide
ndh 2102162 p.Arg294Thr missense_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102164 c.879A>G synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102167 c.876A>G synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102176 c.867T>G synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102182 c.859_861delAGGinsCGC synonymous_variant 0.36 isoniazid
delamanid
ethionamide
ndh 2102190 c.853T>C synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102192 p.Arg284Pro missense_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2102194 c.849T>C synonymous_variant 0.33 isoniazid
delamanid
ethionamide
ndh 2102203 c.840T>A synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102206 c.837G>C synonymous_variant 0.35 isoniazid
delamanid
ethionamide
ndh 2102212 c.831G>C synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102218 c.825C>G synonymous_variant 0.38 isoniazid
delamanid
ethionamide
ndh 2102233 c.810G>A synonymous_variant 0.39 isoniazid Not assoc w R - Interim
delamanid
ethionamide Not assoc w R - Interim
PPE35 2169775 p.Ala280Thr missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517947 c.-168C>T upstream_gene_variant 0.45 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.44 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.47 isoniazid
kasA 2517992 c.-123C>G upstream_gene_variant 0.46 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.36 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.38 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.33 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.3 isoniazid
kasA 2518035 c.-80C>G upstream_gene_variant 0.3 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.29 isoniazid
kasA 2518053 c.-62_-60delATTinsCTG upstream_gene_variant 0.28 isoniazid
kasA 2518059 c.-56_-54delTCGinsACC upstream_gene_variant 0.28 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 0.29 isoniazid
kasA 2518076 c.-39C>T upstream_gene_variant 1.0 isoniazid
kasA 2518079 c.-36T>C upstream_gene_variant 0.3 isoniazid
kasA 2518088 c.-27T>C upstream_gene_variant 0.27 isoniazid
kasA 2518089 c.-26C>A upstream_gene_variant 0.27 isoniazid
kasA 2518094 c.-21G>A upstream_gene_variant 0.27 isoniazid
kasA 2518103 c.-12G>A upstream_gene_variant 0.26 isoniazid
kasA 2518110 c.-5T>A upstream_gene_variant 0.27 isoniazid
kasA 2518121 p.Gln3Lys missense_variant 0.26 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.24 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.43 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.5 isoniazid
kasA 2518540 c.426T>G synonymous_variant 0.5 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.49 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.5 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.5 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.53 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.57 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.55 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.52 isoniazid
kasA 2518621 c.507G>A synonymous_variant 0.6 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.7 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.75 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.79 isoniazid
kasA 2518687 c.573C>T synonymous_variant 0.84 isoniazid
kasA 2518696 c.582C>G synonymous_variant 0.82 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.87 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.84 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.84 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.88 isoniazid
kasA 2518741 c.627G>C synonymous_variant 0.86 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.83 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.76 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.71 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.66 isoniazid
kasA 2518795 c.681C>G synonymous_variant 0.64 isoniazid
kasA 2518816 c.702C>A