Run ID: SRR3675235
Sample name:
Date: 2024-03-25T21:57:53.172842
Number of reads: 283627
Percentage reads mapped: 11.03
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.96 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.96 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | c.346_348delCACinsGG | Assoc w R | High-level resistance |
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.508_510delGTGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.730_732delAACinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.766_768delGCTinsCC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.838_840delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 491290 | c.508_510delGTGinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491512 | c.730_732delAACinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491548 | c.766_768delGCTinsCC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491620 | c.838_840delATCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| katG | 2155764 | c.346_348delCACinsGG | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 753 | c.753C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 767 | p.Val256Ala | missense_variant | 1.0 | isoniazid | |
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7126 | c.-176G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7135 | c.-167G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7153 | c.-149G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7159 | c.1920C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7162 | c.1923C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7165 | c.-137C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7168 | c.-134C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7210 | p.Asp657Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7213 | c.-89G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7216 | c.-86G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7225 | c.-77T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7234 | c.1995C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7243 | c.-59G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7355 | c.54T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7397 | c.96G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7406 | c.105G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7412 | c.111C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7433 | c.132G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7454 | c.153G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7569 | p.Ala90Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7592 | c.291G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7613 | c.312G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7637 | c.336C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7706 | c.405C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7709 | c.408G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7769 | c.468C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7775 | c.474C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7790 | c.489G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7796 | c.495G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7802 | c.501C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7841 | c.540C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7847 | c.546G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8174 | c.873C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8191 | p.Ala297Gly | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8210 | c.909G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8219 | c.918T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8222 | c.921C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8225 | c.924T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8235 | c.934_936delTTAinsCG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8240 | c.939C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8246 | c.945C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8247 | c.946_948delATCinsGG | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8253 | p.Ile318Leu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 0.82 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8456 | c.1155C>T | synonymous_variant | 0.82 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 0.83 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 0.86 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8471 | c.1170T>C | synonymous_variant | 0.9 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8477 | c.1176C>T | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8480 | c.1179C>T | synonymous_variant | 0.91 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8513 | c.1212C>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 0.92 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8535 | p.Glu412Gln | missense_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | p.Asp415Glu | missense_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8571 | c.1270C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8633 | c.1332C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8645 | c.1344C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8649 | p.Arg450Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8663 | c.1362C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8696 | c.1395G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8699 | c.1398A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8705 | c.1404C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8906 | c.1605C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9017 | c.1716C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9293 | c.1992G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9324 | c.2023_2025delTCGinsAGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9341 | c.2040C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044_2046delAGGinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9353 | c.2052G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9356 | c.2055G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9374 | c.2073G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9407 | c.2106C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491248 | p.Arg156Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491255 | p.Lys158Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491271 | c.489C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491307 | c.525C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491310 | c.528C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491313 | c.531C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491316 | c.534C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491321 | p.Ala180Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491346 | c.564C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491352 | c.570C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491355 | c.573C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491367 | c.585G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491370 | c.588C>G | synonymous_variant | 0.87 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491490 | c.708C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491499 | c.717G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491508 | c.726A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491523 | c.741G>C | synonymous_variant | 0.44 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 0.44 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491536 | c.754C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491547 | c.765A>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491562 | c.780C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491563 | c.781_783delAGCinsTCG | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491571 | c.789C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491595 | c.813C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491631 | c.849C>T | synonymous_variant | 0.69 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575692 | c.345G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575725 | c.378C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575744 | p.Ala133Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 575749 | c.402C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575764 | c.417C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575776 | c.429C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575782 | c.435G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575795 | p.Ile150Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575800 | c.453G>C | synonymous_variant | 0.97 | ethionamide | |
| isoniazid | ||||||
| mshA | 575803 | c.456C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575893 | c.546C>G | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| mshA | 575905 | c.558G>A | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575906 | c.559_561delGCAinsTC | frameshift_variant&missense_variant | 0.86 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575916 | p.Asp190Ala | missense_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575920 | c.573C>T | synonymous_variant | 0.86 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575925 | p.Gly193Ala | missense_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575929 | c.582C>G | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575935 | c.588G>A | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| mshA | 575945 | p.Thr200Ala | missense_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| mshA | 575950 | c.603C>G | synonymous_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| ccsA | 620619 | c.729G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620631 | c.741T>C | synonymous_variant | 0.91 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620694 | c.804C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620715 | c.825C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620742 | c.852G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620764 | c.874_876delGCCinsTG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620781 | c.891C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620783 | p.Ala298Val | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620793 | c.903G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620796 | c.906C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| nusG | 734403 | c.150C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734472 | c.219T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734478 | c.225C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734499 | c.246G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734571 | c.318C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760082 | c.276C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760088 | c.282C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760104 | c.298_300delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760136 | c.330G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760139 | c.333A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760178 | c.372G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760181 | c.375T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760244 | c.438G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760298 | c.492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760316 | c.510C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760325 | c.519G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760334 | c.528G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760357 | p.Thr184Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760406 | c.600G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760407 | p.Ser201Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760415 | c.609C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760457 | c.651C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760463 | c.657C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760478 | c.672C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760502 | c.696C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760541 | c.735G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760595 | c.789C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760596 | p.Thr264Pro | missense_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760721 | c.915C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760748 | c.942C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760751 | c.945G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760755 | c.949_951delCATinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 760759 | p.Val318Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760764 | p.Glu320Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 760769 | c.963C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760784 | c.978G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760877 | c.1071G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760883 | c.1077G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760887 | p.Thr361Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760910 | c.1104C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760916 | c.1110C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760919 | c.1113C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761012 | c.1206C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761054 | c.1248G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761063 | c.1257C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761084 | c.1278C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761087 | c.1281C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761088 | c.1282_1284delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761111 | c.1305C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761147 | c.1341C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761165 | c.1359G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761213 | c.1407G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761217 | p.Pro471Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761234 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761288 | c.1482G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761318 | c.1512G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761345 | c.1539G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761367 | p.Glu521Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761374 | p.Val523Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761552 | c.1746G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761555 | c.1749G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761600 | c.1794T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761669 | c.1863C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761675 | c.1869G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761708 | c.1902C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761712 | p.Val636Ile | missense_variant | 1.0 | rifampicin | |
| rpoB | 761718 | c.1912_1913delGCinsT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761722 | p.Glu639Gly | missense_variant | 0.88 | rifampicin | Uncertain significance |
| rpoB | 761727 | p.Ser641Gly | missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926_1927delCGinsGCA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761736 | p.Ile644Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761785 | p.Thr660Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761847 | c.2041_2043delTGCinsCT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761864 | c.2058G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761867 | c.2061C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761868 | c.2062_2064delGACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761892 | p.Ile696Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761915 | p.Asp703Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761921 | c.2115C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762047 | c.2241G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762137 | c.2331C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762158 | c.2352G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762233 | c.2427G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762245 | c.2439G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762284 | c.2478G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762287 | c.2481C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762308 | c.2502G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762341 | c.2535G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 762350 | c.2544C>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.95 | rifampicin | |
| rpoB | 762368 | c.2562G>A | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 762374 | c.-996G>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.95 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.96 | rifampicin | |
| rpoC | 762443 | c.-927G>C | upstream_gene_variant | 0.96 | rifampicin | |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 762452 | c.2646G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762491 | c.2685T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoB | 762515 | c.2709C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762557 | c.-813G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762833 | c.3027C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762839 | c.-531G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762879 | c.3073_3075delATGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 762920 | c.3114C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 762959 | c.3153G>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763004 | c.3198G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763007 | c.3201C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763053 | c.3247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763103 | c.-267G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763130 | c.3324G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763133 | c.-237G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763136 | c.3330C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763142 | c.-228C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763160 | c.-210G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763190 | c.-180C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763199 | c.-171G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763205 | c.-165G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763206 | c.-164_-163delAGinsTC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763217 | c.-153G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763227 | p.Leu1141Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 763232 | c.-138C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763235 | p.Glu1143Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 763241 | p.Glu1145Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763259 | c.-111G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763375 | c.6C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763423 | p.Glu18Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 763430 | c.61_63delAGGinsCT | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763433 | c.64_66delCAAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763443 | p.Tyr25Phe | missense_variant | 1.0 | rifampicin | |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763468 | c.99G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763492 | c.123G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763558 | c.189C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763600 | c.231C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763615 | c.246G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763618 | c.249C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763660 | c.291T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>A | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763709 | c.340C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763717 | c.348T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763723 | c.354G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763732 | c.363C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763747 | c.378G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763765 | c.396T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 0.98 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763831 | c.462A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763837 | c.468G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763840 | c.471G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763861 | c.492C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763882 | c.513G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763900 | c.531G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763921 | c.552G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763924 | c.555G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763933 | c.564C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763969 | c.600C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763978 | c.609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763991 | p.Ile208Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764029 | p.Glu220Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 764032 | p.Asp221Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764084 | p.Asn239Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 764089 | c.720C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764102 | p.Val245Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 764153 | p.Gln262Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 764161 | c.792G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764182 | p.Asp271Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | c.826_828delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764207 | p.Val280Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764215 | c.846A>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764217 | p.Asn283Ser | missense_variant | 0.94 | rifampicin | |
| rpoC | 764227 | c.858G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764239 | c.870T>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764254 | c.885G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764257 | c.888G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764263 | c.894G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764293 | c.924G>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 764297 | p.Met310Leu | missense_variant | 0.93 | rifampicin | |
| rpoC | 764344 | c.975C>T | synonymous_variant | 0.86 | rifampicin | |
| rpoC | 764353 | c.984G>T | synonymous_variant | 0.88 | rifampicin | Not assoc w R - Interim |
| rpoC | 764365 | c.996C>T | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764371 | c.1002G>C | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764387 | c.1018T>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036_1038delAGGinsCC | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoC | 764435 | c.1066_1068delAGGinsCA | frameshift_variant&missense_variant | 0.93 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764485 | c.1116G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764491 | c.1122G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764500 | c.1131C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764524 | c.1155C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764527 | c.1158C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764536 | c.1167G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764605 | c.1236G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764611 | c.1242G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764623 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764701 | c.1332C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764707 | c.1338G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764713 | c.1344G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764746 | c.1377G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
| rpoC | 764803 | c.1434C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764827 | c.1458G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764869 | c.1500C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764875 | c.1506C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764912 | p.Met515Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 764935 | c.1566T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | c.2014_2016delATGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765403 | c.2034G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765404 | p.Leu679Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765425 | p.Lys686Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765445 | c.2076G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765452 | p.Ala695Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765466 | c.2097C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765480 | p.Tyr704Phe | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765496 | c.2127C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765778 | c.2409C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765779 | c.2410_2412delGACinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765800 | p.Phe811Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765814 | c.2445A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765817 | c.2448G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765823 | c.2454C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765871 | c.2502T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765904 | c.2535C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765908 | c.2539C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765940 | c.2571A>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765946 | c.2577C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765947 | c.2578T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 765952 | c.2583G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 765961 | c.2592G>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 765962 | c.2593T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766579 | c.3210C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766618 | c.3249G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766624 | c.3255G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766634 | p.Phe1089Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 766638 | p.Lys1090Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766658 | c.3289_3291delCGGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766675 | c.3306C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766690 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766694 | c.3325_3327delCAGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766714 | c.3345G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766717 | c.3348C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766720 | c.3351C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766741 | c.3372G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766771 | c.3402G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766775 | p.Arg1136Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766807 | c.3438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766837 | c.3468G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766981 | c.3612T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767008 | c.3639G>A | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 767020 | c.3651C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767104 | c.3735C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767105 | c.3736_3738delAACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767138 | c.3769C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767162 | p.Asn1265Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 767167 | c.3798C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767174 | p.Asn1269Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767197 | c.3828G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| mmpL5 | 775814 | c.2667C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775817 | c.2664T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mmpL5 | 775829 | c.2652C>G | synonymous_variant | 0.73 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775834 | p.Ala883Ser | missense_variant | 0.44 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775838 | c.2643G>C | synonymous_variant | 0.47 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775847 | c.2634G>T | synonymous_variant | 0.63 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mmpL5 | 775851 | p.Ser877Thr | missense_variant | 0.46 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775853 | c.2628C>T | synonymous_variant | 0.35 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775856 | c.2625T>C | synonymous_variant | 0.92 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775862 | c.2619G>C | synonymous_variant | 0.43 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775865 | c.2616T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775877 | c.2604C>G | synonymous_variant | 0.37 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775883 | c.2596_2598delATCinsTG | frameshift_variant&missense_variant | 0.64 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775886 | c.2595A>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775892 | c.2589C>T | synonymous_variant | 0.41 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775904 | c.2577G>A | synonymous_variant | 0.66 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.59 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775915 | p.Ala856Ser | missense_variant | 0.67 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775916 | c.2565T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775919 | c.2560_2562delCTGinsGC | frameshift_variant&missense_variant | 0.58 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775922 | c.2559G>A | synonymous_variant | 0.34 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.55 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775940 | c.2541C>T | synonymous_variant | 0.58 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775951 | c.2530C>T | synonymous_variant | 0.81 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.77 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775970 | c.2511G>C | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.76 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775981 | p.Leu834Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 775994 | c.2485_2487delATCinsCG | frameshift_variant&missense_variant | 0.95 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 775997 | c.2484T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776000 | c.2479_2481delCTGinsAC | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776005 | p.Ile826Leu | missense_variant | 0.95 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776009 | c.2472A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776030 | c.2451G>C | synonymous_variant | 0.95 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776039 | c.2442C>A | synonymous_variant | 0.9 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776047 | c.2434C>T | synonymous_variant | 0.85 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776053 | c.2428T>C | synonymous_variant | 0.89 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776075 | c.2406C>G | synonymous_variant | 0.77 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776081 | c.2400G>C | synonymous_variant | 0.85 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776084 | c.2397C>G | synonymous_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 776087 | c.2394C>G | synonymous_variant | 0.82 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781732 | c.174_177delGAGT | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781739 | c.180_181insCGGC | frameshift_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781742 | c.183C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781772 | c.213C>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781814 | c.255C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781817 | c.258G>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781829 | c.270G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781838 | c.279G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781841 | c.282C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781859 | c.300T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781901 | c.342C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800543 | c.-266C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800570 | c.-239C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800574 | c.-235_-234delGTinsAC | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800579 | c.-230C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800594 | c.-215C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800597 | c.-212A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800603 | c.-206G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800633 | c.-176T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800645 | c.-164C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800678 | c.-131C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800684 | c.-125G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800702 | c.-107G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800735 | c.-74C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800856 | c.48A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800862 | c.54C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800873 | p.Arg22Lys | missense_variant | 1.0 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800880 | c.72A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800892 | c.84G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800895 | c.87C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800904 | c.96G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800921 | p.Arg38Leu | missense_variant | 1.0 | linezolid | |
| rplC | 800928 | c.120C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800931 | c.123G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800964 | c.156G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801205 | p.Arg133Ala | missense_variant | 1.0 | linezolid | |
| rplC | 801210 | c.402T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801220 | p.Ser138Ala | missense_variant | 1.0 | linezolid | |
| rplC | 801231 | c.423C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801237 | c.429G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801252 | c.444G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801267 | c.459A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801281 | p.Ala158Gly | missense_variant | 1.0 | linezolid | |
| rplC | 801285 | c.477G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801307 | c.499_501delGCCinsTG | frameshift_variant&missense_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801315 | c.507G>T | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304562 | c.1632G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304567 | p.Phe546Tyr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304571 | c.1641G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304671 | p.Val581Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304675 | p.Gly582Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304694 | c.1764A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304715 | c.1785G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304751 | c.1821C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364640 | c.228G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364643 | c.231C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364644 | p.Lys78Gln | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364650 | p.Thr80Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364661 | c.249C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364667 | c.255T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364679 | c.267T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364682 | c.270G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364691 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364709 | c.297T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364712 | c.300T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364721 | c.309C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364724 | c.312C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364751 | c.339C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364847 | c.435G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364865 | c.453G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364867 | p.Ala152Gly | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364871 | c.459C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364877 | c.465G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364883 | c.471G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364898 | c.486C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364922 | p.Glu170Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364925 | c.513C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364931 | c.519C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364950 | c.538_540delGCAinsTG | frameshift_variant&stop_gained | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364962 | c.550_552delCCTinsGC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461137 | c.93C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461155 | c.111C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461159 | p.Val39Ile | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| atpE | 1461167 | c.123G>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461170 | c.126A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461179 | c.135G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461182 | c.138A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461224 | c.180T>G | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472106 | n.261G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Not assoc w R | |||||
| amikacin | Not assoc w R | |||||
| rrs | 1472446 | n.601T>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472452 | n.607G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473110 | n.1265T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473111 | n.1266A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473291 | n.1446_1447insT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1475991 | n.2334T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476099 | n.2442A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476105 | n.2448G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476160 | n.2503T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476256 | n.2599A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476540 | n.2883C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476664 | n.3007T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476665 | n.3008T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476674 | n.3017T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476679 | n.3022T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476725 | n.3068C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476731 | n.3074G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476746 | n.3089T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476747 | n.3090C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476754 | n.3097G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673682 | c.-520G>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| inhA | 1673703 | c.-499C>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673708 | c.270_271delCC | frameshift_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673714 | c.275_276insT | frameshift_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673717 | c.278_279insA | frameshift_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673724 | c.-478A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673730 | c.-472C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673745 | c.-457G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673748 | c.-454A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673749 | p.Lys104Arg | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673760 | p.Lys107Asn | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673772 | c.-430C>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673778 | c.-424C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673784 | c.-418G>T | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673787 | c.-415G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673799 | c.-403T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673802 | c.-400A>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673808 | c.-394A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673877 | c.-325C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673905 | p.Ser156Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673916 | c.-286A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673917 | p.Val160Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673922 | c.-280T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673931 | c.-271C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673941 | c.502_504delGCCinsTG | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673952 | c.-250G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673955 | c.-247G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673961 | c.-241A>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1673962 | p.Asn175Gly | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673967 | c.-235G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1673973 | c.-229G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| inhA | 1673976 | c.-226T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| fabG1 | 1674006 | p.Asp189Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674024 | c.-178T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833589 | c.48A>C | synonymous_variant | 0.92 | pyrazinamide | |
| rpsA | 1833595 | c.54T>G | synonymous_variant | 0.92 | pyrazinamide | |
| rpsA | 1833596 | p.Ser19Ala | missense_variant | 0.92 | pyrazinamide | |
| rpsA | 1833616 | c.75A>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1833628 | c.87G>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833634 | c.93G>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833664 | c.123C>A | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833676 | c.135A>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833679 | c.138G>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833685 | c.144G>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833694 | c.153G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833697 | c.156C>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833703 | c.162C>T | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833709 | c.168C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833724 | c.183C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833730 | c.189C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833733 | c.192C>T | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833734 | p.Ala65Ser | missense_variant | 0.97 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833808 | c.267G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833829 | c.288A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833862 | c.321G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833894 | p.Ala118Glu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833904 | c.363G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833970 | c.429G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833976 | c.435C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833991 | c.450C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834009 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834012 | c.471G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834154 | c.613_615delAACinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834168 | c.627C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834169 | p.Thr210Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834213 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834234 | c.693G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834246 | c.705G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834252 | c.711C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834279 | c.738C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834345 | c.804C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834361 | c.820T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834396 | c.855G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834498 | c.957C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834513 | c.972C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834520 | p.Ala327Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834554 | c.1014_1015delTG | frameshift_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834558 | c.1017_1018insAG | frameshift_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834606 | c.1065C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834666 | c.1125G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834667 | p.Ala376Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834753 | c.1212T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834774 | c.1233C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834776 | p.Ala412Glu | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834829 | c.1288_1290delGCGinsAC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853375 | c.-231G>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853417 | c.-189G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853441 | c.-165C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 1.0 | linezolid | |
| katG | 2155674 | c.438G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155680 | c.432G>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155696 | p.Ala139Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155742 | p.Gly124Arg | missense_variant | 1.0 | isoniazid | |
| katG | 2155747 | p.Ala122Gly | missense_variant | 1.0 | isoniazid | |
| katG | 2155749 | c.363C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155752 | c.360C>T | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155769 | p.Ile115Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155770 | c.342C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155782 | c.330C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 0.95 | isoniazid | |
| kasA | 2517959 | c.-156C>T | upstream_gene_variant | 0.95 | isoniazid | |
| kasA | 2517962 | c.-153C>G | upstream_gene_variant | 0.95 | isoniazid | |
| kasA | 2517968 | c.-147T>C | upstream_gene_variant | 0.94 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.93 | isoniazid | |
| kasA | 2517980 | c.-135C>T | upstream_gene_variant | 0.93 | isoniazid | |
| kasA | 2517989 | c.-126T>G | upstream_gene_variant | 0.95 | isoniazid | |
| kasA | 2517993 | c.-122G>T | upstream_gene_variant | 0.95 | isoniazid | |
| kasA | 2518726 | c.612G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518732 | c.618C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518756 | c.642G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518780 | p.Glu222Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518785 | p.Glu224Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518787 | c.673_675delCGGinsGT | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518792 | c.678C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518813 | c.699C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518816 | c.702C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518843 | c.729T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518847 | p.Leu245Met | missense_variant | 1.0 | isoniazid | |
| kasA | 2518853 | p.Leu247Ile | missense_variant | 1.0 | isoniazid | |
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783371 | c.672A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783386 | c.657G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783419 | c.624G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | p.Pro206Lys | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783446 | c.597A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2681 | 2996350 | c.-389C>G | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996354 | c.-385C>T | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996360 | p.Met86Leu | missense_variant | 1.0 | capreomycin | |
| Rv2680 | 2996366 | c.262_264delTATinsCC | frameshift_variant&missense_variant | 1.0 | capreomycin | Uncertain significance |
| Rv2681 | 2996374 | c.-365G>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996381 | c.277_279delTCCinsGG | frameshift_variant&missense_variant | 1.0 | capreomycin | Uncertain significance |
| Rv2680 | 2996386 | p.Asp94Glu | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996389 | c.-350A>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996401 | c.-338T>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996404 | p.Ile100Met | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996407 | c.-332C>T | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996410 | c.-329G>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996419 | c.-320T>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996420 | p.Val106Ile | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996440 | c.-299G>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996443 | c.-296T>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996446 | c.342A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| Rv2681 | 2996449 | c.-290C>T | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996458 | c.-281C>A | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996461 | c.-278G>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996470 | c.-269G>A | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2752c | 3065022 | c.1170G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065058 | c.1134C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065061 | c.1131C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065070 | c.1122C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065079 | c.1113T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065082 | c.1110G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065085 | c.1105_1107delAGGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065109 | c.1081_1083delAGAinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065126 | p.Ser356Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065130 | c.1062A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065142 | c.1050A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065154 | c.1038G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065160 | c.1032C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065166 | c.1026C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065925 | c.267G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065947 | p.Gly82Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065955 | c.235_237delTTGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065958 | c.234G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065961 | c.231G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065967 | c.225G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065972 | p.Ile74Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065976 | p.Asp72Glu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065979 | c.213T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065982 | c.210G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065988 | c.204A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065994 | c.198T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065997 | c.195C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066002 | p.Met64Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066018 | c.174T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyA | 3073920 | c.552C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073926 | c.546G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073962 | c.510G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073971 | c.501C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625243 | c.-333T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625252 | c.1362G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625255 | c.-345T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625258 | c.-348G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625264 | c.1350C>T | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625285 | c.-375G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625291 | c.-381A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625297 | c.-387C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625657 | c.-747C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625663 | c.-753G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625711 | c.903C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625732 | c.882C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625735 | c.-825C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625753 | p.Ala287Gln | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625770 | c.-860C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625801 | c.-891G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625804 | c.808_810delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625828 | c.-918G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625845 | p.Ser257Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625852 | c.-942A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625855 | c.759G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626774 | c.574_576delAGGinsCT | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626786 | c.-173A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626792 | c.-179G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877647 | c.861C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877671 | c.837C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | c.831G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877683 | c.825G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877695 | c.813C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877728 | c.780C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877731 | c.777G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877734 | c.774G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877749 | c.759C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877785 | c.723C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877848 | c.660C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877856 | c.652T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877875 | c.633T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877878 | c.630G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877887 | c.621G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877893 | c.615C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | c.600T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877926 | c.582G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877971 | p.Asp179Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877986 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877995 | c.513G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878019 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878034 | c.474A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878040 | c.468T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878046 | c.462T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878050 | p.Arg153Lys | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878061 | c.447G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878127 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878143 | p.Gly122Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878145 | c.363C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878197 | p.Glu104Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878238 | c.270C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878244 | c.264G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878247 | c.261G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878301 | c.207C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878310 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878352 | c.156C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878373 | c.135G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| ddn | 3986615 | c.-229C>A | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986616 | c.-228_-227delAGinsGC | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986622 | c.-222C>T | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986633 | c.-211C>T | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986661 | c.-183C>A | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986667 | c.-177_-175delCTCinsACG | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4038410 | c.2295C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038419 | c.2286T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038434 | c.2271G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038462 | p.Ala748Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038474 | p.Ser744Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038479 | c.2226C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038489 | p.Ala739Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038519 | p.Arg729Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038533 | p.Arg724Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038536 | c.2169C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038551 | c.2154C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038563 | c.2142C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038584 | c.2121G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038587 | c.2118C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038602 | c.2103G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038647 | c.2058T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038660 | c.2044_2045delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038679 | p.Pro676Ala | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038698 | c.2007C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038725 | c.1980C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038767 | c.1938G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038770 | c.1935C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038776 | c.1929G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038779 | c.1926C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038842 | c.1863G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038890 | c.1815G>A | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038905 | c.1800A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038911 | c.1794G>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038917 | c.1788C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038941 | c.1764G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>T | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039064 | c.1641C>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039067 | c.1638G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039079 | c.1626C>G | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039091 | c.1614G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>T | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039100 | c.1605C>T | synonymous_variant | 0.97 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039118 | c.1587C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | c.1536A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039187 | c.1518G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039241 | c.1464G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039310 | c.1395A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039313 | c.1392C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039320 | p.Ala462Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039352 | c.1353C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039361 | c.1344C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039394 | c.1311G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039397 | c.1308A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039454 | c.1251A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039472 | c.1233G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039478 | c.1227G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039487 | c.1218G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039541 | c.1164C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039559 | c.1146C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039570 | p.Met379Leu | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039574 | p.Ala377Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039589 | c.1116G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039592 | c.1113G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039649 | c.1056G>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039652 | c.1053G>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039670 | c.1035G>C | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.93 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039742 | c.963C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039802 | c.903G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039823 | c.882T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039829 | c.874_876delTTGinsCC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039832 | c.873C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039883 | c.822G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039889 | c.816G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039949 | c.756G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039985 | c.720G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040003 | c.702G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040042 | c.663C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040087 | c.618G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040126 | c.579C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040306 | c.399G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040309 | c.396C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040324 | c.381G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040335 | c.370C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040336 | c.369G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040345 | c.360C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040366 | c.339C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040390 | c.315C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040433 | c.271_272delAGinsTC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040441 | c.264C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040444 | c.261C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040462 | c.243C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040468 | c.237G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040477 | c.228G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040495 | c.210C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040546 | c.159G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040591 | c.114C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040594 | c.111G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040600 | c.105A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040603 | c.102T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040618 | c.87C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040648 | c.57G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040654 | c.51G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| glpK | 4138565 | c.1191G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138634 | c.1122G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138643 | c.1113A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138661 | c.1095T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138670 | c.1086G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138696 | p.Pro354Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | ||||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138697 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138703 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138727 | c.1029C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138747 | c.1009C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138763 | c.993G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138769 | c.987G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138778 | c.978C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138781 | c.975G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138799 | c.957T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138808 | c.948G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138817 | c.937_939delGCTinsTG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138822 | p.Asn312Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138823 | c.933G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138829 | c.927A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138847 | c.909A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4240717 | c.855T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240828 | c.966G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247401 | c.888T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247407 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247426 | p.Gly305Gln | missense_variant | 1.0 | ethambutol | |
| embB | 4247434 | c.921C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247437 | c.924A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247440 | c.927C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247449 | c.936C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247455 | c.942C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247464 | c.951C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247511 | p.Tyr333Phe | missense_variant | 1.0 | ethambutol | |
| embB | 4247527 | c.1014G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247536 | c.1023C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247555 | c.1042_1044delCTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247578 | c.1065_1066insATCTGT | conservative_inframe_insertion | 1.0 | ethambutol | |
| embB | 4247581 | c.1069_1074delGCCGGG | conservative_inframe_deletion | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247629 | c.1116C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248088 | c.1575C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248112 | c.1599C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248118 | c.1605T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248130 | c.1617G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248133 | c.1620C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248142 | c.1629T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630_1632delTTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248158 | p.Cys549Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248163 | c.1650G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248167 | p.Thr552Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248170 | p.Ala553Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4248173 | p.Val554Leu | missense_variant | 1.0 | ethambutol | |
| embB | 4248199 | c.1686A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248205 | c.1692C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248220 | c.1707A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248225 | p.Ala571Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
