Run ID: ERR4814536
Sample name:
Date: 2024-04-15T04:36:03.849147
Number of reads: 3755701
Percentage reads mapped: 60.42
Median coverage: 70.0
Strain: M.canetti;lineage2.1;lineage3
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage3 | East-African-Indian | RD750 | 0.89 |
lineage2.1 | East-Asian (non-Beijing) | None | 0.06 |
M.canetti | M.canetti | None | 0.08 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
p.Ser450Leu | Assoc w R | |||
rpoC | p.Leu527Val | Uncertain significance | Mutation from literature | |
isoniazid | katG | p.Ile335Thr | Mutation from literature | |
p.Ser315Thr | Assoc w R | High-level resistance | ||
c.496_498delGTTinsAC | Assoc w R | High-level resistance | ||
ethambutol | embA | c.-12C>T | Uncertain significance | Mutation from literature |
embB | p.His312Arg | Mutation from literature | ||
p.Ala388Gly | Mutation from literature | |||
p.Asn399Asp | Mutation from literature | |||
pyrazinamide | ||||
streptomycin | rpsL | p.Lys43Arg | Assoc w R | |
rrs | n.462C>T | Uncertain significance | Mutation from literature | |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.730_732delAACinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
c.838_840delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiC | c.550_552delCAAinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1039_1041delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1948_1950delCGCinsAG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 491512 | c.730_732delAACinsGG | frameshift_variant&missense_variant | 0.39 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491620 | c.838_840delATCinsGG | frameshift_variant&missense_variant | 0.27 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 0.37 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
rpoB | 761155 | p.Ser450Leu | missense_variant | 0.55 | rifampicin | Assoc w R | |
rpoC | 764948 | p.Leu527Val | missense_variant | 0.68 | rifampicin | Uncertain significance | Mutation from literature |
rpsL | 781687 | p.Lys43Arg | missense_variant | 0.66 | streptomycin | Assoc w R | |
fbiC | 1303480 | c.550_552delCAAinsGG | frameshift_variant&missense_variant | 0.28 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 0.38 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 0.35 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303969 | c.1039_1041delGTTinsAC | frameshift_variant&missense_variant | 0.56 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304878 | c.1948_1950delCGCinsAG | frameshift_variant&missense_variant | 0.28 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 0.39 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.35 | streptomycin | Uncertain significance | Mutation from literature |
katG | 2155108 | p.Ile335Thr | missense_variant | 0.24 | isoniazid | Mutation from literature | |
katG | 2155168 | p.Ser315Thr | missense_variant | 0.99 | isoniazid | Assoc w R | High-level resistance |
katG | 2155614 | c.496_498delGTTinsAC | frameshift_variant&missense_variant | 0.21 | isoniazid | Assoc w R | High-level resistance |
embA | 4243221 | c.-12C>T | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
embB | 4247448 | p.His312Arg | missense_variant | 0.42 | ethambutol | Mutation from literature | |
embB | 4247676 | p.Ala388Gly | missense_variant | 0.21 | ethambutol | Mutation from literature | |
embB | 4247708 | p.Asn399Asp | missense_variant | 0.28 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 180 | c.180T>C | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
dnaA | 571 | c.571T>C | synonymous_variant | 0.34 | isoniazid | |
dnaA | 576 | c.576G>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 591 | c.591C>G | synonymous_variant | 0.39 | isoniazid | |
dnaA | 600 | c.600T>C | synonymous_variant | 0.36 | isoniazid | |
dnaA | 609 | c.609C>G | synonymous_variant | 0.34 | isoniazid | |
dnaA | 610 | c.610C>T | synonymous_variant | 0.4 | isoniazid | |
dnaA | 636 | c.636C>G | synonymous_variant | 0.31 | isoniazid | |
dnaA | 645 | c.645A>G | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 654 | c.654A>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.28 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.28 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.27 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.29 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.35 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.31 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.32 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.24 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.2 | isoniazid | |
dnaA | 843 | c.843T>C | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
dnaA | 846 | c.846T>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 876 | c.876C>G | synonymous_variant | 0.2 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 0.2 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.29 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.35 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.42 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.41 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1164 | c.1164A>T | synonymous_variant | 0.31 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.33 | isoniazid | Not assoc w R - Interim |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.32 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.3 | isoniazid | |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.31 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.33 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.37 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.38 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.41 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.36 | isoniazid | |
dnaA | 1293 | c.1293T>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1302 | c.1302C>G | synonymous_variant | 0.37 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1461 | c.1461C>A | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1464 | c.1464T>C | synonymous_variant | 0.28 | isoniazid | |
dnaA | 1470 | c.1470C>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 1473 | c.1473T>C | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 1485 | c.1485A>G | synonymous_variant | 0.19 | isoniazid | |
gyrB | 5339 | p.Ile34Val | missense_variant | 0.96 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrB | 5806 | c.567C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5809 | c.570C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5815 | c.576C>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5824 | c.585A>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 5848 | c.609G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6123 | p.Ala295Gly | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6133 | c.894G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrB | 6148 | c.909C>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6169 | c.930C>G | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6209 | c.970C>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6217 | c.978G>C | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.29 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6325 | c.-977C>G | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6727 | c.-575G>T | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.33 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6778 | c.-524C>T | upstream_gene_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.32 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6824 | c.1585C>T | synonymous_variant | 0.36 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>G | upstream_gene_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6911 | p.Asn558His | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.36 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7487 | c.186C>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7490 | c.189C>T | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7517 | c.216G>A | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7538 | c.237G>A | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7571 | c.270G>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7607 | c.306C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7622 | c.321C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7683 | c.382A>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7710 | c.409T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7760 | c.459C>T | synonymous_variant | 0.47 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.45 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.38 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7835 | c.534A>G | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7838 | c.537C>G | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7859 | c.558A>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7883 | c.582G>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7884 | c.583_585delCGTinsGC | frameshift_variant&missense_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7898 | p.Asp199Glu | missense_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7919 | p.Glu206Asp | missense_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7923 | p.His208Tyr | missense_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7928 | p.Asp209Glu | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8078 | c.777A>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8090 | c.789C>G | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8174 | c.873C>G | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.46 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.43 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8351 | c.1050C>T | synonymous_variant | 0.38 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 0.35 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.35 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8442 | c.1141C>T | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8462 | c.1161A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8498 | c.1197C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8537 | c.1236G>A | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8552 | c.1251C>G | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8556 | p.Ala419Gln | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8562 | c.1261C>T | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8645 | c.1344C>G | synonymous_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8796 | c.1495_1497delATCinsGG | frameshift_variant&missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 0.41 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 0.39 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 0.37 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8918 | c.1617C>G | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8945 | c.1644G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8948 | p.Leu549Phe | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8951 | c.1650G>A | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.28 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 0.19 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9062 | c.1761C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9065 | c.1764C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9074 | c.1773G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9227 | c.1926C>G | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9233 | c.1932C>T | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.35 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9278 | c.1977G>C | synonymous_variant | 0.31 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9281 | c.1980C>G | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9311 | c.2010C>T | synonymous_variant | 0.4 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.4 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.39 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.37 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.32 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9629 | c.2328C>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9630 | p.Val777Ile | missense_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9635 | c.2334T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9644 | c.2343T>C | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9647 | c.2346C>T | synonymous_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9650 | c.2349G>C | synonymous_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9665 | c.2364A>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9666 | p.Arg789Gly | missense_variant | 0.31 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9674 | c.2373T>C | synonymous_variant | 0.34 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9677 | c.2376C>T | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9701 | c.2400T>C | synonymous_variant | 0.34 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9704 | c.2403T>C | synonymous_variant | 0.33 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9708 | c.2407T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9722 | c.2421C>T | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9734 | c.2433A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.18 | isoniazid | |
Rv0010c | 13906 | c.-348C>T | upstream_gene_variant | 0.19 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 0.21 | isoniazid | |
fgd1 | 490794 | c.12G>C | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490797 | c.15G>A | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490800 | c.18A>C | synonymous_variant | 0.19 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 490803 | c.21T>A | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490833 | c.51G>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490842 | c.60C>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490851 | c.69A>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490887 | c.105G>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490902 | c.120T>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>A | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491137 | p.Glu119Gln | missense_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Glu | missense_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491166 | c.384G>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491196 | c.414A>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 0.45 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 0.46 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.4 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491319 | c.537G>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491331 | c.549G>A | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 0.29 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491472 | c.690A>G | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491502 | c.720G>A | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491508 | c.726A>G | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491509 | c.727T>C | synonymous_variant | 0.39 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491532 | c.750G>T | synonymous_variant | 0.42 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491583 | c.801G>A | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491595 | c.813C>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
mshA | 574616 | c.-732G>C | upstream_gene_variant | 0.21 | ethionamide | |
isoniazid | ||||||
mshA | 574625 | c.-723C>G | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 574650 | c.-698A>C | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 574655 | c.-693C>G | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | ||||||
mshA | 574664 | c.-684G>C | upstream_gene_variant | 0.2 | ethionamide | |
isoniazid | ||||||
mshA | 575084 | c.-264T>C | upstream_gene_variant | 0.18 | ethionamide | |
isoniazid | ||||||
mshA | 575536 | c.189T>C | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
mshA | 575542 | c.195C>G | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
mshA | 575561 | p.Met72Val | missense_variant | 0.2 | ethionamide | |
isoniazid | ||||||
mshA | 575569 | c.222A>G | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
mshA | 575571 | p.Ser75Thr | missense_variant | 0.19 | ethionamide | |
isoniazid | ||||||
mshA | 575575 | c.228G>C | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
mshA | 575587 | c.240C>A | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
mshA | 575590 | c.243T>C | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
mshA | 575593 | c.246G>C | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
mshA | 575623 | c.276C>G | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575629 | c.282A>C | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
mshA | 575635 | c.288A>C | synonymous_variant | 0.24 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575638 | c.291T>C | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
mshA | 575641 | c.294A>G | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
mshA | 575648 | p.Val101Gln | missense_variant | 0.28 | ethionamide | |
isoniazid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575665 | c.318G>C | synonymous_variant | 0.32 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575689 | c.342G>C | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.31 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.41 | ethionamide | |
isoniazid | ||||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.41 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.43 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.45 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 0.46 | ethionamide | |
isoniazid | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 0.42 | ethionamide | |
isoniazid | ||||||
mshA | 575878 | c.531A>G | synonymous_variant | 0.38 | ethionamide | |
isoniazid | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 0.33 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
ccsA | 619502 | c.-389_-388delAAinsCG | upstream_gene_variant | 0.24 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 0.26 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619531 | c.-360T>G | upstream_gene_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 0.28 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619558 | c.-333G>C | upstream_gene_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619564 | c.-327C>G | upstream_gene_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.47 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.45 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.48 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.54 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619627 | c.-264C>G | upstream_gene_variant | 0.47 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619633 | c.-258G>A | upstream_gene_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619648 | c.-243C>G | upstream_gene_variant | 0.43 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619654 | c.-237A>C | upstream_gene_variant | 0.42 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619655 | c.-236A>G | upstream_gene_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619669 | c.-222G>C | upstream_gene_variant | 0.33 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>C | upstream_gene_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619697 | c.-194A>C | upstream_gene_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620198 | p.Gln103Leu | missense_variant | 0.26 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620245 | c.355T>C | synonymous_variant | 0.27 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620249 | p.Ser120Cys | missense_variant | 0.26 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620257 | p.Ile123Val | missense_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620265 | c.375C>G | synonymous_variant | 0.24 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620269 | p.Val127Ile | missense_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620275 | c.385C>T | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>C | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.32 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>G | synonymous_variant | 0.36 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.41 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.39 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.4 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.4 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620433 | c.543C>G | synonymous_variant | 0.34 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>C | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 0.29 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 0.3 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620460 | c.570T>C | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620461 | p.Val191Ile | missense_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620481 | c.591T>G | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620482 | p.Val198Leu | missense_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620607 | c.717T>G | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620619 | c.729G>C | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620622 | c.732G>C | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620631 | c.741T>C | synonymous_variant | 0.25 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 0.35 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 0.34 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620703 | c.813G>C | synonymous_variant | 0.35 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620710 | c.820_822delGTGinsAC | frameshift_variant&missense_variant | 0.31 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 0.28 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 0.25 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620730 | c.840C>T | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 0.17 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620745 | c.855G>C | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 0.24 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620784 | c.894C>G | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620787 | c.897C>G | synonymous_variant | 0.23 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620809 | c.919C>T | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620829 | c.939G>C | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656582 | p.Leu297Met | missense_variant | 0.16 | ethionamide | |
Rv0565c | 657081 | c.390G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657219 | p.Ala84Val | missense_variant | 0.18 | ethionamide | |
Rv0565c | 657222 | c.249C>G | synonymous_variant | 0.18 | ethionamide | |
Rv0565c | 657231 | c.238_240delATCinsGG | frameshift_variant&missense_variant | 0.21 | ethionamide | Uncertain significance |
Rv0565c | 657237 | c.234A>G | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 657242 | p.Glu77Lys | missense_variant | 0.35 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.31 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.29 | ethionamide | |
Rv0565c | 657291 | c.180C>G | synonymous_variant | 0.3 | ethionamide | |
Rv0565c | 657300 | c.171C>T | synonymous_variant | 0.28 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 0.17 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 0.17 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.24 | ethionamide | |
Rv0565c | 657656 | c.-186C>T | upstream_gene_variant | 0.22 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 0.21 | ethionamide | |
Rv0565c | 657690 | c.-220C>A | upstream_gene_variant | 0.17 | ethionamide | |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 0.15 | isoniazid | |
hadA | 731741 | c.-189G>A | upstream_gene_variant | 0.17 | isoniazid | |
hadA | 731753 | c.-177A>G | upstream_gene_variant | 0.18 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 0.23 | isoniazid | |
hadA | 732304 | c.375C>T | synonymous_variant | 0.25 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 0.26 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 0.26 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 0.3 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.35 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.36 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.39 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.37 | isoniazid | |
hadA | 732389 | p.Ser154Thr | missense_variant | 0.37 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.31 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.31 | isoniazid | |
nusG | 734078 | c.-176C>A | upstream_gene_variant | 0.19 | rifampicin | |
nusG | 734144 | c.-110G>C | upstream_gene_variant | 0.18 | rifampicin | |
nusG | 734147 | c.-107T>C | upstream_gene_variant | 0.18 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 0.19 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 0.22 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 0.21 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.2 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.23 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.24 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
nusG | 734481 | c.228C>G | synonymous_variant | 0.27 | rifampicin | |
nusG | 734499 | c.246G>C | synonymous_variant | 0.39 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.37 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
nusG | 734595 | c.342C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
nusG | 734634 | c.381G>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734703 | c.450T>C | synonymous_variant | 0.25 | rifampicin | |
nusG | 734709 | c.456T>G | synonymous_variant | 0.21 | rifampicin | |
nusG | 734715 | c.462G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734718 | c.465G>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734719 | p.Ser156Ala | missense_variant | 0.2 | rifampicin | |
nusG | 734726 | p.Arg158Lys | missense_variant | 0.22 | rifampicin | |
nusG | 734732 | p.Ala160Val | missense_variant | 0.19 | rifampicin | |
nusG | 734754 | c.501G>C | synonymous_variant | 0.33 | rifampicin | |
nusG | 734757 | c.504T>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
nusG | 734778 | c.525G>C | synonymous_variant | 0.34 | rifampicin | |
nusG | 734781 | c.528A>G | synonymous_variant | 0.3 | rifampicin | |
nusG | 734792 | p.Val180Ala | missense_variant | 0.25 | rifampicin | |
nusG | 734794 | p.Val181Ile | missense_variant | 0.26 | rifampicin | Uncertain significance |
nusG | 734820 | c.567A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
nusG | 734826 | c.573A>G | synonymous_variant | 0.29 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
nusG | 734832 | c.579C>G | synonymous_variant | 0.3 | rifampicin | |
nusG | 734841 | c.588G>A | synonymous_variant | 0.3 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 0.27 | rifampicin | |
nusG | 734853 | c.600A>C | synonymous_variant | 0.27 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 0.28 | rifampicin | |
nusG | 734865 | c.612G>C | synonymous_variant | 0.31 | rifampicin | |
nusG | 734882 | p.Ala210Gly | missense_variant | 0.28 | rifampicin | |
nusG | 734886 | c.633A>G | synonymous_variant | 0.28 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 0.28 | rifampicin | |
nusG | 734910 | c.657C>G | synonymous_variant | 0.21 | rifampicin | |
nusG | 734940 | c.687G>A | synonymous_variant | 0.16 | rifampicin | |
rpoB | 759606 | c.-201T>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoB | 759746 | c.-61C>T | upstream_gene_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 760106 | c.300G>T | synonymous_variant | 0.25 | rifampicin | |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760118 | c.312T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.37 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.46 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.52 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.39 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.38 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.36 | rifampicin | |
rpoB | 760340 | c.534G>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.35 | rifampicin | Uncertain significance |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.33 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.32 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.27 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 0.28 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.35 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>G | synonymous_variant | 0.32 | rifampicin | |
rpoB | 760721 | c.915C>G | synonymous_variant | 0.3 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 0.21 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760845 | p.Thr347Pro | missense_variant | 0.25 | rifampicin | |
rpoB | 760859 | c.1053T>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.34 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.29 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.46 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.46 | rifampicin | |
rpoB | 761171 | c.1365C>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 761183 | c.1377T>G | synonymous_variant | 0.44 | rifampicin | |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.4 | rifampicin | |
rpoB | 761213 | c.1407G>A | synonymous_variant | 0.38 | rifampicin | |
rpoB | 761222 | c.1416G>C | synonymous_variant | 0.36 | rifampicin | |
rpoB | 761231 | c.1425C>G | synonymous_variant | 0.34 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 761301 | c.1495C>A | synonymous_variant | 0.51 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.34 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.22 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.32 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsG | frameshift_variant&synonymous_variant | 0.24 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.31 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.32 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.3 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.24 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.26 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.24 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.28 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.27 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761847 | p.Cys681Ser | missense_variant | 0.18 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.17 | rifampicin | |
rpoB | 761930 | c.2124G>A | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.4 | rifampicin | |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.46 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.45 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.2 | rifampicin | Uncertain significance |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>G | synonymous_variant | 0.41 | rifampicin | |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.35 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.27 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.19 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 762374 | c.-996G>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoC | 762380 | c.-990T>G | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 762434 | c.2628T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoB | 762490 | p.Val895Asp | missense_variant | 0.17 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.25 | rifampicin | |
rpoC | 762521 | c.-849C>G | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.24 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.26 | rifampicin | |
rpoB | 762799 | p.Ala998Gly | missense_variant | 0.18 | rifampicin | Uncertain significance |
rpoB | 762857 | c.3051C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.46 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.45 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.63 | rifampicin | Not assoc w R |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763076 | c.-294C>G | upstream_gene_variant | 0.41 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.32 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.25 | rifampicin | |
rpoB | 763206 | p.Ser1134Cys | missense_variant | 0.16 | rifampicin | |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 763441 | c.72C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 763658 | c.289_291delCTTinsTG | frameshift_variant&missense_variant | 0.26 | rifampicin | |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>A | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763768 | c.399C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.23 | rifampicin | |
rpoC | 763783 | c.414G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763819 | c.450G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763831 | c.462A>G | synonymous_variant | 0.22 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.21 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.4 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.39 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 763960 | c.591T>C | synonymous_variant | 0.42 | rifampicin | Not assoc w R - Interim |
rpoC | 763967 | p.Gly200Ser | missense_variant | 0.4 | rifampicin | |
rpoC | 763978 | c.609C>G | synonymous_variant | 0.42 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 0.22 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764161 | c.792G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Gln | missense_variant | 0.34 | rifampicin | |
rpoC | 764203 | c.834G>T | synonymous_variant | 0.35 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764282 | c.913_915delTCGinsAGC | synonymous_variant | 0.3 | rifampicin | |
rpoC | 764320 | c.951C>G | synonymous_variant | 0.34 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 0.33 | rifampicin | |
rpoC | 764405 | c.1036A>C | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.34 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 764470 | c.1101C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 0.29 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>C | synonymous_variant | 0.5 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 0.48 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.5 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.44 | rifampicin | Not assoc w R - Interim |
rpoC | 764779 | c.1410G>A | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.37 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.37 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.49 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.46 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.41 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R |
rpoC | 765034 | c.1665T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765073 | c.1704G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765085 | c.1716T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>A | synonymous_variant | 0.38 | rifampicin | Not assoc w R - Interim |
rpoC | 765287 | c.1918C>T | synonymous_variant | 0.31 | rifampicin | |
rpoC | 765292 | c.1923G>T | synonymous_variant | 0.32 | rifampicin | |
rpoC | 765298 | c.1929G>C | synonymous_variant | 0.34 | rifampicin | |
rpoC | 765300 | p.Val644Ala | missense_variant | 0.35 | rifampicin | Uncertain significance |
rpoC | 765319 | c.1950A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 0.32 | rifampicin | Uncertain significance |
rpoC | 765330 | p.Ser654Asn | missense_variant | 0.33 | rifampicin | Uncertain significance |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.38 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.35 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.37 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 0.25 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.39 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.43 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 0.4 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.44 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.38 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.41 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 765985 | c.2616C>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766009 | c.2640G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.42 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.43 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.48 | rifampicin | |
rpoC | 766069 | c.2700G>A | synonymous_variant | 0.44 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.4 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.29 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.4 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.31 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.36 | rifampicin | Not assoc w R - Interim |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.32 | rifampicin | |
rpoC | 766531 | c.3162G>T | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.24 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.26 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 766594 | c.3225G>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766597 | c.3228C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 766607 | c.3238_3240delATCinsCG | frameshift_variant&missense_variant | 0.3 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766666 | c.3297C>G | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766738 | c.3369G>T | synonymous_variant | 0.34 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.38 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>C | synonymous_variant | 0.39 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.4 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.41 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.33 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766978 | c.3609C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.19 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767074 | c.3705T>C | synonymous_variant | 0.27 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>G | synonymous_variant | 0.25 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 767167 | c.3798C>G | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 0.3 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 767221 | c.3852C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.21 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.22 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776030 | c.2451G>C | synonymous_variant | 0.19 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781608 | c.49_51delAGTinsGC | frameshift_variant&missense_variant | 0.21 | streptomycin | Uncertain significance |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.36 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.31 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.34 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.33 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.26 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.27 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.28 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.36 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.41 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.35 | linezolid | |
rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.38 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.37 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.26 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.27 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 0.32 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.33 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.31 | linezolid | |
rplC | 800794 | c.-15_-9delAGATTGGinsGAGTT | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.29 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.28 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.32 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.32 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.3 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 0.28 | linezolid | |
rplC | 800877 | c.69A>C | synonymous_variant | 0.25 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 0.24 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 0.29 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 0.3 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.31 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 0.31 | linezolid | |
rplC | 800939 | p.Arg44Gln | missense_variant | 0.3 | linezolid | |
rplC | 800946 | c.138T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 800955 | c.147C>G | synonymous_variant | 0.31 | linezolid | |
rplC | 800967 | c.159C>G | synonymous_variant | 0.29 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 0.26 | linezolid | Not assoc w R - Interim |
rplC | 800982 | c.174C>T | synonymous_variant | 0.25 | linezolid | |
rplC | 800985 | c.177A>G | synonymous_variant | 0.22 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801150 | c.342G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 0.19 | linezolid | |
rplC | 801156 | c.348T>A | synonymous_variant | 0.19 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 0.32 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.33 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 0.37 | linezolid | |
rplC | 801228 | c.420T>C | synonymous_variant | 0.35 | linezolid | |
rplC | 801246 | c.438C>G | synonymous_variant | 0.33 | linezolid | |
rplC | 801249 | c.441T>G | synonymous_variant | 0.37 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.35 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 0.26 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 0.23 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 0.17 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.19 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.22 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.27 | linezolid | |
rplC | 801396 | c.588T>C | synonymous_variant | 0.28 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.27 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.27 | linezolid | |
rplC | 801417 | c.609T>C | synonymous_variant | 0.23 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.21 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.17 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
fbiC | 1303455 | c.525C>G | synonymous_variant | 0.24 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303464 | c.534A>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303470 | c.540T>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303476 | c.546G>C | synonymous_variant | 0.29 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303560 | c.630G>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303638 | c.708A>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303660 | p.Val244Thr | missense_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.32 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303701 | c.771C>G | synonymous_variant | 0.43 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 0.33 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 0.37 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.49 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.45 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.48 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.51 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.52 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303881 | c.951G>C | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303920 | c.990C>G | synonymous_variant | 0.53 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303923 | c.993C>T | synonymous_variant | 0.56 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303929 | c.999G>C | synonymous_variant | 0.6 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>C | synonymous_variant | 0.55 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303973 | p.Gly348Ala | missense_variant | 0.59 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303981 | p.Val351Ile | missense_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303995 | c.1065C>T | synonymous_variant | 0.62 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304001 | c.1071C>G | synonymous_variant | 0.57 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304040 | c.1110C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304049 | c.1119T>G | synonymous_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304058 | c.1128G>A | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304059 | c.1129C>T | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304080 | p.Ala384Ser | missense_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304545 | p.Val539Thr | missense_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.35 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304628 | c.1698G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.25 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.38 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304790 | c.1860C>G | synonymous_variant | 0.37 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.4 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.41 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.54 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 0.61 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 0.65 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>G | synonymous_variant | 0.83 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.66 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304872 | c.1942_1944delAGCinsTCG | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304877 | c.1947T>C | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.34 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304934 | c.2004C>G | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.36 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304991 | c.2061G>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | c.2065T>C | synonymous_variant | 0.3 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.29 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>A | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305027 | c.2097G>A | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305297 | c.2367G>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305300 | c.2370A>G | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305303 | c.2373T>C | synonymous_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305311 | p.Arg794Gln | missense_variant | 0.31 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305336 | c.2406T>C | synonymous_variant | 0.42 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305381 | c.2451G>C | synonymous_variant | 0.47 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305397 | p.Glu823Gln | missense_variant | 0.44 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>G | synonymous_variant | 0.38 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305420 | c.2490C>G | synonymous_variant | 0.28 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305423 | c.2493T>C | synonymous_variant | 0.27 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305430 | p.Val834Thr | missense_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305444 | c.2514A>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305453 | c.2523C>G | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364679 | c.267T>C | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364691 | c.279T>C | synonymous_variant | 0.23 | pyrazinamide | |
sigE | 1364712 | c.300T>C | synonymous_variant | 0.27 | pyrazinamide | |
sigE | 1364718 | c.306C>T | synonymous_variant | 0.26 | pyrazinamide | |
sigE | 1364727 | c.315C>T | synonymous_variant | 0.24 | pyrazinamide | |
sigE | 1364736 | c.324T>C | synonymous_variant | 0.24 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364742 | c.330A>G | synonymous_variant | 0.25 | pyrazinamide | |
sigE | 1364748 | c.336G>C | synonymous_variant | 0.27 | pyrazinamide | |
sigE | 1364767 | c.355A>C | synonymous_variant | 0.19 | pyrazinamide | |
sigE | 1364784 | c.372C>G | synonymous_variant | 0.28 | pyrazinamide | |
sigE | 1364790 | c.378T>C | synonymous_variant | 0.3 | pyrazinamide | |
sigE | 1364802 | c.390C>A | synonymous_variant | 0.29 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.33 | pyrazinamide | |
sigE | 1364820 | c.408A>G | synonymous_variant | 0.34 | pyrazinamide | |
sigE | 1364835 | c.423C>G | synonymous_variant | 0.38 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.4 | pyrazinamide | |
sigE | 1364862 | c.450C>G | synonymous_variant | 0.4 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.38 | pyrazinamide | |
sigE | 1364866 | c.454_456delGCTinsTG | frameshift_variant&missense_variant | 0.37 | pyrazinamide | Uncertain significance |
sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 0.26 | pyrazinamide | Uncertain significance |
sigE | 1364904 | p.Asp164Glu | missense_variant | 0.25 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364928 | c.516C>T | synonymous_variant | 0.15 | pyrazinamide | |
atpE | 1461113 | c.69C>T | synonymous_variant | 0.15 | bedaquiline | |
atpE | 1461132 | p.Val30Ile | missense_variant | 0.18 | bedaquiline | |
atpE | 1461149 | c.105T>G | synonymous_variant | 0.22 | bedaquiline | |
atpE | 1461150 | c.106_108delATCinsGT | frameshift_variant&missense_variant | 0.22 | bedaquiline | |
atpE | 1461159 | p.Val39Ile | missense_variant | 0.24 | bedaquiline | Uncertain significance |
atpE | 1461185 | c.141G>C | synonymous_variant | 0.33 | bedaquiline | |
atpE | 1461189 | c.145C>T | synonymous_variant | 0.29 | bedaquiline | |
atpE | 1461194 | c.150C>T | synonymous_variant | 0.31 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 0.31 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 0.25 | bedaquiline | |
atpE | 1461224 | c.180T>C | synonymous_variant | 0.22 | bedaquiline | |
atpE | 1461233 | c.189A>G | synonymous_variant | 0.19 | bedaquiline | |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.36 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.25 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.28 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.32 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472030 | n.185G>A | non_coding_transcript_exon_variant | 0.32 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.32 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.33 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>C | non_coding_transcript_exon_variant | 0.34 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.37 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.36 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.32 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472866 | n.1021C>T | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.29 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.29 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.32 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.3 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.36 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473290 | n.1445delCinsTTT | non_coding_transcript_exon_variant | 0.48 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.33 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.52 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.68 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473944 | n.287G>A | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1473945 | n.288T>C | non_coding_transcript_exon_variant | 0.67 | capreomycin | |
linezolid | ||||||
rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 0.73 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.37 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.38 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1475206 | n.1549C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475209 | n.1552G>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.39 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.65 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.48 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.42 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.34 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.45 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476755 | n.3098G>A | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 0.26 | capreomycin | |
linezolid | ||||||
rrl | 1476770 | n.3113T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1476771 | n.3114G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
inhA | 1673574 | c.-628C>G | upstream_gene_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1673580 | c.-622T>C | upstream_gene_variant | 0.24 | ethionamide | |
isoniazid | Uncertain significance | |||||
inhA | 1673589 | c.-613A>G | upstream_gene_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1673607 | c.-595T>C | upstream_gene_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1673610 | c.-592C>T | upstream_gene_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1673616 | c.-586A>G | upstream_gene_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1673619 | c.-583T>C | upstream_gene_variant | 0.22 | ethionamide | |
isoniazid | ||||||
fabG1 | 1673633 | p.Ser65Asn | missense_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1673646 | c.-556T>C | upstream_gene_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674280 | c.79C>A | synonymous_variant | 0.15 | ethionamide | |
isoniazid | ||||||
inhA | 1674285 | c.84A>G | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1674303 | c.102C>G | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1674307 | c.106C>T | synonymous_variant | 0.26 | ethionamide | |
isoniazid | ||||||
inhA | 1674315 | c.114C>G | synonymous_variant | 0.37 | ethionamide | |
isoniazid | ||||||
inhA | 1674321 | c.120G>C | synonymous_variant | 0.39 | ethionamide | |
isoniazid | ||||||
inhA | 1674342 | c.141T>C | synonymous_variant | 0.35 | ethionamide | |
isoniazid | ||||||
inhA | 1674352 | p.Thr51Val | missense_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674368 | p.Ala56Glu | missense_variant | 0.24 | ethionamide | |
isoniazid | ||||||
inhA | 1674379 | c.178C>T | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674382 | p.Leu61Ile | missense_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674387 | c.186A>G | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674399 | c.198A>G | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674461 | p.Lys87Arg | missense_variant | 0.27 | ethionamide | |
isoniazid | ||||||
inhA | 1674480 | c.279T>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674486 | c.285T>C | synonymous_variant | 0.33 | ethionamide | |
isoniazid | ||||||
inhA | 1674489 | c.288G>C | synonymous_variant | 0.35 | ethionamide | |
isoniazid | ||||||
inhA | 1674507 | c.306G>C | synonymous_variant | 0.33 | ethionamide | |
isoniazid | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.37 | ethionamide | |
isoniazid | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.35 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
inhA | 1674564 | c.363C>T | synonymous_variant | 0.29 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.3 | ethionamide | |
isoniazid | ||||||
inhA | 1674624 | c.423A>C | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
inhA | 1674627 | c.426T>G | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
inhA | 1674630 | c.429C>G | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 0.29 | ethionamide | |
isoniazid | ||||||
inhA | 1674639 | c.438C>T | synonymous_variant | 0.32 | ethionamide | |
isoniazid | ||||||
inhA | 1674654 | c.453G>C | synonymous_variant | 0.36 | ethionamide | |
isoniazid | ||||||
inhA | 1674693 | c.492C>G | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1674703 | c.502T>C | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674718 | c.517A>C | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1674879 | c.678T>C | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674903 | c.702T>C | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1674904 | c.703_705delGCGinsCC | frameshift_variant&missense_variant | 0.27 | ethionamide | |
isoniazid | ||||||
inhA | 1674909 | c.708G>C | synonymous_variant | 0.28 | ethionamide | |
isoniazid | ||||||
inhA | 1674915 | c.714C>G | synonymous_variant | 0.31 | ethionamide | |
isoniazid | ||||||
inhA | 1674942 | c.741T>C | synonymous_variant | 0.33 | ethionamide | |
isoniazid | ||||||
inhA | 1674957 | c.756G>C | synonymous_variant | 0.3 | ethionamide | |
isoniazid | ||||||
inhA | 1674963 | c.762G>C | synonymous_variant | 0.25 | ethionamide | |
isoniazid | ||||||
inhA | 1674966 | c.765T>C | synonymous_variant | 0.23 | ethionamide | |
isoniazid | ||||||
inhA | 1674967 | p.Asp256Thr | missense_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674993 | c.792G>C | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674994 | p.His265Ser | missense_variant | 0.21 | ethionamide | |
isoniazid | ||||||
rpsA | 1833367 | c.-175G>T | upstream_gene_variant | 0.16 | pyrazinamide | |
rpsA | 1833541 | c.-1T>C | upstream_gene_variant | 0.26 | pyrazinamide | |
rpsA | 1833554 | p.Thr5Ala | missense_variant | 0.31 | pyrazinamide | Uncertain significance |
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.34 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1833790 | c.249T>A | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833799 | c.258C>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833862 | c.321G>T | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834097 | c.556_557delTCinsAG | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834261 | c.720A>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834297 | c.756C>G | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.38 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.45 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.45 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.44 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.37 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834498 | c.957C>T | synonymous_variant | 0.39 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.32 | pyrazinamide | |
rpsA | 1834558 | c.1017C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834606 | c.1065C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.33 | pyrazinamide | |
rpsA | 1834666 | c.1125G>C | synonymous_variant | 0.4 | pyrazinamide | |
rpsA | 1834669 | c.1128G>C | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834688 | c.1147_1149delAGTinsTCC | synonymous_variant | 0.38 | pyrazinamide | |
rpsA | 1834726 | c.1185C>A | synonymous_variant | 0.43 | pyrazinamide | |
rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834733 | p.Ala398Pro | missense_variant | 0.41 | pyrazinamide | |
rpsA | 1834753 | c.1212T>C | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834765 | c.1224A>G | synonymous_variant | 0.46 | pyrazinamide | |
rpsA | 1834780 | c.1239A>G | synonymous_variant | 0.41 | pyrazinamide | |
rpsA | 1834786 | c.1245A>G | synonymous_variant | 0.42 | pyrazinamide | |
rpsA | 1834789 | c.1248T>C | synonymous_variant | 0.36 | pyrazinamide | |
rpsA | 1834792 | c.1251G>C | synonymous_variant | 0.37 | pyrazinamide | |
tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 0.34 | linezolid | |
tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 0.31 | linezolid | |
tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 0.35 | linezolid | |
tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 0.36 | linezolid | |
tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 0.36 | linezolid | |
tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 0.48 | linezolid | |
tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.46 | linezolid | |
tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 0.46 | linezolid | |
tsnR | 1853447 | c.-159C>G | upstream_gene_variant | 0.48 | linezolid | |
tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 0.48 | linezolid | |
tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 0.5 | linezolid | |
tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 0.46 | linezolid | |
tsnR | 1853484 | c.-122_-121delAGinsGC | upstream_gene_variant | 0.47 | linezolid | |
tsnR | 1853495 | c.-111G>C | upstream_gene_variant | 0.43 | linezolid | |
tsnR | 1853498 | c.-108G>C | upstream_gene_variant | 0.41 | linezolid | |
tsnR | 1853531 | c.-75A>G | upstream_gene_variant | 0.28 | linezolid | |
tsnR | 1853540 | c.-66A>G | upstream_gene_variant | 0.23 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917951 | c.12T>C | synonymous_variant | 0.19 | capreomycin | |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
tlyA | 1917981 | c.42G>C | synonymous_variant | 0.18 | capreomycin | |
tlyA | 1918464 | c.525C>G | synonymous_variant | 0.19 | capreomycin | |
tlyA | 1918476 | c.537A>C | synonymous_variant | 0.22 | capreomycin | |
tlyA | 1918477 | p.Leu180Met | missense_variant | 0.22 | capreomycin | |
bacA | 2064912 | c.-184A>G | upstream_gene_variant | 0.21 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064933 | c.-205A>G | upstream_gene_variant | 0.22 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064936 | c.-208C>A | upstream_gene_variant | 0.2 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064945 | c.-217G>A | upstream_gene_variant | 0.22 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064948 | c.-220G>C | upstream_gene_variant | 0.21 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064963 | c.-235G>C | upstream_gene_variant | 0.22 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
bacA | 2064972 | c.-244T>C | upstream_gene_variant | 0.21 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
ndh | 2101960 | c.1083A>G | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101966 | c.1077T>G | synonymous_variant | 0.22 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101972 | c.1071G>C | synonymous_variant | 0.21 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2101978 | c.1063_1065delAACinsGT | frameshift_variant&missense_variant | 0.2 | ethionamide | Uncertain significance |
delamanid | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
ndh | 2101988 | p.Ala352Gly | missense_variant | 0.23 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102009 | p.Ser345Asn | missense_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102020 | c.1023A>G | synonymous_variant | 0.23 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102023 | c.1020G>C | synonymous_variant | 0.23 | ethionamide | |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2102026 | c.1017G>C | synonymous_variant | 0.26 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102050 | c.993T>C | synonymous_variant | 0.28 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102053 | c.990G>C | synonymous_variant | 0.28 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102059 | c.984T>C | synonymous_variant | 0.23 | ethionamide | Not assoc w R - Interim |
delamanid | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2102065 | c.978G>C | synonymous_variant | 0.22 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102068 | c.975T>C | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102076 | p.Met323Leu | missense_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102077 | c.966T>C | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102083 | c.958_960delGTGinsAC | frameshift_variant&missense_variant | 0.24 | ethionamide | Uncertain significance |
delamanid | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
ndh | 2102092 | c.951G>C | synonymous_variant | 0.23 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102098 | c.945G>C | synonymous_variant | 0.27 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102103 | p.Tyr314His | missense_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102104 | c.939G>C | synonymous_variant | 0.23 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102110 | c.933T>C | synonymous_variant | 0.24 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102133 | p.Gln304Lys | missense_variant | 0.15 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102218 | c.825C>G | synonymous_variant | 0.19 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102233 | c.810G>A | synonymous_variant | 0.33 | ethionamide | Not assoc w R - Interim |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2102242 | c.801G>A | synonymous_variant | 0.35 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102305 | c.738T>C | synonymous_variant | 0.29 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102317 | c.726A>G | synonymous_variant | 0.22 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102596 | c.447C>G | synonymous_variant | 0.18 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102599 | c.444T>C | synonymous_variant | 0.22 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102604 | p.Leu147Val | missense_variant | 0.25 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102608 | c.433_435delTTGinsCC | frameshift_variant&missense_variant | 0.24 | ethionamide | Uncertain significance |
delamanid | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Not assoc w R |
katG | 2155020 | c.1092C>T | synonymous_variant | 0.21 | isoniazid | |
katG | 2155029 | c.1083C>G | synonymous_variant | 0.23 | isoniazid | |
katG | 2155032 | c.1080T>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
katG | 2155054 | p.Tyr353Phe | missense_variant | 0.35 | isoniazid | |
katG | 2155056 | c.1056A>G | synonymous_variant | 0.34 | isoniazid | |
katG | 2155062 | c.1050T>C | synonymous_variant | 0.36 | isoniazid | |
katG | 2155065 | c.1047C>G | synonymous_variant | 0.35 | isoniazid | |
katG | 2155068 | c.1044T>C | synonymous_variant | 0.35 | isoniazid | |
katG | 2155071 | c.1041T>C | synonymous_variant | 0.35 | isoniazid | |
katG | 2155080 | c.1032G>C | synonymous_variant | 0.34 | isoniazid | |
katG | 2155113 | c.999C>G | synonymous_variant | 0.2 | isoniazid | |
katG | 2155590 | c.522A>G | synonymous_variant | 0.2 | isoniazid | |
katG | 2155617 | c.495T>C | synonymous_variant | 0.21 | isoniazid | Not assoc w R - Interim |
katG | 2155632 | c.480A>C | synonymous_variant | 0.29 | isoniazid | |
katG | 2155637 | p.Leu159Ile | missense_variant | 0.31 | isoniazid | |
katG | 2155641 | p.Lys157Asn | missense_variant | 0.32 | isoniazid | Uncertain significance |
katG | 2155677 | c.435C>G | synonymous_variant | 0.26 | isoniazid | |
katG | 2155680 | c.432G>C | synonymous_variant | 0.26 | isoniazid | |
katG | 2155691 | c.421T>C | synonymous_variant | 0.24 | isoniazid | |
katG | 2155695 | p.Ala139Val | missense_variant | 0.22 | isoniazid | |
katG | 2155701 | c.411C>T | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
katG | 2155704 | c.408C>G | synonymous_variant | 0.23 | isoniazid | |
katG | 2155716 | c.396T>C | synonymous_variant | 0.21 | isoniazid | |
katG | 2155722 | c.390G>C | synonymous_variant | 0.22 | isoniazid | |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
pncA | 2289047 | c.195C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R |
pncA | 2289365 | c.-125delC | upstream_gene_variant | 1.0 | pyrazinamide | |
pncA | 2289991 | c.-750G>C | upstream_gene_variant | 0.24 | pyrazinamide | |
pncA | 2289994 | c.-753A>G | upstream_gene_variant | 0.24 | pyrazinamide | |
pncA | 2289997 | c.-756G>C | upstream_gene_variant | 0.27 | pyrazinamide | |
pncA | 2290006 | c.-765T>C | upstream_gene_variant | 0.26 | pyrazinamide | |
pncA | 2290009 | c.-768A>G | upstream_gene_variant | 0.25 | pyrazinamide | |
pncA | 2290015 | c.-774A>C | upstream_gene_variant | 0.24 | pyrazinamide | |
pncA | 2290027 | c.-786G>A | upstream_gene_variant | 0.23 | pyrazinamide | |
kasA | 2517947 | c.-168C>T | upstream_gene_variant | 0.48 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.4 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.33 | isoniazid | |
kasA | 2517992 | c.-123C>G | upstream_gene_variant | 0.33 | isoniazid | |
kasA | 2518019 | c.-96A>G | upstream_gene_variant | 0.25 | isoniazid | |
kasA | 2518025 | c.-90G>C | upstream_gene_variant | 0.25 | isoniazid | |
kasA | 2518031 | c.-84G>T | upstream_gene_variant | 0.2 | isoniazid | |
kasA | 2518162 | c.48G>A | synonymous_variant | 0.16 | isoniazid | |
kasA | 2518174 | c.60A>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518190 | p.Ser26Ala | missense_variant | 0.25 | isoniazid | |
kasA | 2518199 | p.Ile29Val | missense_variant | 0.25 | isoniazid | |
kasA | 2518222 | c.108G>A | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518223 | c.109_111delTTGinsCC | frameshift_variant&missense_variant | 0.21 | isoniazid | |
kasA | 2518234 | c.120G>A | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518483 | c.369C>G | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.27 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518540 | c.426T>G | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.34 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.35 | isoniazid | |
kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 0.34 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.44 | isoniazid | |
kasA | 2518621 | c.507G>A | synonymous_variant | 0.49 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.51 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.5 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.47 | isoniazid | |
kasA | 2518687 | c.573C>T | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.49 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.37 | isoniazid | |
kasA | 2518717 | c.603C>T | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.32 | isoniazid | |
kasA | 2518741 | c.627G>C | synonymous_variant | 0.33 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2518768 | c.654C>G | synonymous_variant | 0.43 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.48 | isoniazid | |
kasA | 2518792 | c.678C>G | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518822 | c.708C>G | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.4 | isoniazid | |
kasA | 2518855 | c.741C>G | synonymous_variant | 0.41 | isoniazid | |
kasA | 2518864 | c.750G>C | synonymous_variant | 0.36 | isoniazid | |
kasA | 2518879 | c.765A>G | synonymous_variant | 0.3 | isoniazid | |
kasA | 2518885 | c.771T>C | synonymous_variant | 0.27 | isoniazid | |
kasA | 2518898 | c.784T>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518910 | p.Leu266Met | missense_variant | 0.18 | isoniazid | |
kasA | 2519095 | c.981C>G | synonymous_variant | 0.2 | isoniazid | |
kasA | 2519098 | c.984C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2519104 | c.990T>A | synonymous_variant | 0.16 | isoniazid | |
kasA | 2519111 | p.Gln333Glu | missense_variant | 0.18 | isoniazid | |
kasA | 2519116 | c.1002C>G | synonymous_variant | 0.21 | isoniazid | |
kasA | 2519125 | c.1011C>T | synonymous_variant | 0.2 | isoniazid | |
kasA | 2519137 | c.1023T>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2519146 | c.1032C>A | synonymous_variant | 0.23 | isoniazid | |
kasA | 2519167 | c.1053T>C | synonymous_variant | 0.28 | isoniazid | |
kasA | 2519173 | c.1059C>G | synonymous_variant | 0.31 | isoniazid | |
kasA | 2519176 | c.1062G>A | synonymous_variant | 0.3 | isoniazid | |
kasA | 2519197 | c.1083G>C | synonymous_variant | 0.3 | isoniazid | |
kasA | 2519215 | c.1101C>T | synonymous_variant | 0.27 | isoniazid | |
kasA | 2519221 | c.1107G>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2519225 | c.1111C>T | synonymous_variant | 0.18 | isoniazid | |
ahpC | 2726105 | c.-88G>A | upstream_gene_variant | 1.0 | isoniazid | Not assoc w R |
ahpC | 2726288 | c.96C>T | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
ahpC | 2726354 | c.162G>C | synonymous_variant | 0.18 | isoniazid | |
ahpC | 2726357 | c.165A>G | synonymous_variant | 0.19 | isoniazid | Not assoc w R - Interim |
ahpC | 2726564 | c.372C>T | synonymous_variant | 0.17 | isoniazid | Not assoc w R - Interim |
ahpC | 2726579 | c.387T>C | synonymous_variant | 0.22 | isoniazid | |
ahpC | 2726591 | c.399C>G | synonymous_variant | 0.28 | isoniazid | |
ahpC | 2726593 | p.Val134Ala | missense_variant | 0.28 | isoniazid | |
ahpC | 2726600 | c.408T>C | synonymous_variant | 0.32 | isoniazid | |
ahpC | 2726612 | c.420C>G | synonymous_variant | 0.36 | isoniazid | |
ahpC | 2726638 | p.Ala149Val | missense_variant | 0.3 | isoniazid | |
ahpC | 2726645 | c.453C>G | synonymous_variant | 0.28 | isoniazid | |
ahpC | 2726657 | c.465A>C | synonymous_variant | 0.25 | isoniazid | Not assoc w R - Interim |
ahpC | 2726669 | p.Asp159Glu | missense_variant | 0.25 | isoniazid | |
ahpC | 2726672 | c.480G>A | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
ahpC | 2726681 | c.489A>G | synonymous_variant | 0.21 | isoniazid | |
ahpC | 2726687 | c.495C>G | synonymous_variant | 0.19 | isoniazid | |
folC | 2746979 | p.Ala207Asp | missense_variant | 0.17 | para-aminosalicylic_acid | |
folC | 2746987 | c.612T>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
folC | 2747007 | p.Ser198Cys | missense_variant | 0.16 | para-aminosalicylic_acid | |
folC | 2747023 | c.576C>G | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
folC | 2747032 | c.567A>C | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
folC | 2747040 | p.Ile187Val | missense_variant | 0.26 | para-aminosalicylic_acid | |
folC | 2747059 | c.540T>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
folC | 2747065 | c.534C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
folC | 2747086 | c.513A>C | synonymous_variant | 0.31 | para-aminosalicylic_acid | |
folC | 2747089 | c.510G>C | synonymous_variant | 0.3 | para-aminosalicylic_acid | |
folC | 2747098 | c.501C>G | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
folC | 2747101 | c.498G>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
folC | 2747107 | c.492G>C | synonymous_variant | 0.29 | para-aminosalicylic_acid | |
folC | 2747110 | c.489T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
folC | 2747113 | c.486C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
folC | 2747116 | c.483G>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
folC | 2747275 | c.324T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
folC | 2747281 | c.318A>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
folC | 2747289 | p.Pro104Ala | missense_variant | 0.25 | para-aminosalicylic_acid | |
folC | 2747290 | c.309A>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
folC | 2747293 | c.306G>A | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
folC | 2747302 | c.297A>G | synonymous_variant | 0.34 | para-aminosalicylic_acid | |
folC | 2747314 | c.285A>C | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
folC | 2747317 | c.282C>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
folC | 2747355 | p.Val82Ile | missense_variant | 0.28 | para-aminosalicylic_acid | |
folC | 2747359 | c.240C>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
folC | 2747362 | c.237G>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
Rv2477c | 2782447 | c.1596C>T | synonymous_variant | 0.3 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782450 | c.1593C>G | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782453 | c.1590C>A | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 0.36 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782498 | c.1545C>T | synonymous_variant | 0.59 | ethambutol | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R | |||||
Rv2477c | 2782510 | c.1533G>C | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782528 | c.1515G>C | synonymous_variant | 0.4 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782537 | c.1506T>G | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782549 | c.1494T>C | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2782558 | c.1485T>C | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782561 | c.1482G>C | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782567 | c.1476C>G | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783020 | c.1023G>C | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.23 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783062 | c.981C>G | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.32 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.32 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.35 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783110 | c.933C>A | synonymous_variant | 0.46 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.47 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.49 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783158 | c.885A>G | synonymous_variant | 0.44 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.41 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.37 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783203 | c.840C>T | synonymous_variant | 0.38 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>T | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783235 | c.808T>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783243 | p.Thr267Ser | missense_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783247 | c.796T>C | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783254 | c.789A>G | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783302 | c.741A>G | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783320 | c.723C>T | synonymous_variant | 0.29 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783332 | c.711T>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783350 | c.693T>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783353 | c.690T>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783359 | c.684G>A | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783362 | c.681G>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783365 | c.678C>T | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783373 | p.Glu224Gln | missense_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>C | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783416 | c.625_627delATCinsGG | frameshift_variant&missense_variant | 0.2 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783422 | c.621T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783425 | c.616_618delCCCinsGG | frameshift_variant&missense_variant | 0.19 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783434 | c.609C>G | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783473 | c.570A>G | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783485 | c.558G>C | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783494 | c.549C>G | synonymous_variant | 0.23 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783502 | c.541T>C | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.32 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783548 | c.495T>C | synonymous_variant | 0.35 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783551 | c.492G>A | synonymous_variant | 0.35 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783563 | c.480A>G | synonymous_variant | 0.34 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||