Run ID: ERR2693245
Sample name:
Date: 2024-04-15T04:20:28.378030
Number of reads: 700961
Percentage reads mapped: 35.29
Median coverage: 25.0
Strain: La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4.3.2.1 | Euro-American (LAM) | RD761 | 0.07 |
| lineage4.6.4 | Euro-American | None | 0.11 |
| lineage3.1.2.2 | East-African-Indian | RD750 | 0.07 |
| lineage4 | Euro-American | None | 0.79 |
| lineage2.1 | East-Asian (non-Beijing) | None | 0.08 |
| lineage4.8.1 | Euro-American (mainly T) | RD219 | 0.07 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.87 |
| La1.7.1 | M.bovis | None | 0.09 |
| La3 | M.orygis | None | 0.17 |
| La1.6 | M.bovis | None | 0.2 |
| M.canetti | M.canetti | None | 0.05 |
| La1.7.X-unk4 | M.bovis | None | 0.08 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | c.496_498delGTTinsAC | Assoc w R | High-level resistance |
| ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
| p.Tyr384Asn | Mutation from literature | |||
| p.Ala388Gly | Mutation from literature | |||
| pyrazinamide | ||||
| streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | pepQ | c.592_594delGCCinsCG | Assoc w R - Interim | |
| para-aminosalicylic_acid | ||||
| delamanid | fgd1 | c.301_303delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| c.730_732delAACinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiC | c.391_393delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.916_918delTTCinsAG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiA | c.598_600delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.607_609delCTGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.772_774delACGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| fbiB | c.88_90delAGCinsGT | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
| c.343_345delCGGinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| c.391_393delACCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
| bedaquiline | pepQ | c.592_594delGCCinsCG | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV |
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| fgd1 | 491083 | c.301_303delGTTinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fgd1 | 491512 | c.730_732delAACinsGG | frameshift_variant&missense_variant | 0.92 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303321 | c.391_393delGTTinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiC | 1303846 | c.916_918delTTCinsAG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
| katG | 2155614 | c.496_498delGTTinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
| pepQ | 2859825 | c.592_594delGCCinsCG | frameshift_variant&synonymous_variant | 1.0 | clofazimine | Assoc w R - Interim | |
| bedaquiline | Assoc w R - Interim | Includes data from one site that only submitted resistant strains, which may have inflated the PPV | |||||
| fbiA | 3641140 | c.598_600delATCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiA | 3641149 | c.607_609delCTGinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiA | 3641314 | c.772_774delACGinsGC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiB | 3641622 | c.88_90delAGCinsGT | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiB | 3641877 | c.343_345delCGGinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| fbiB | 3641925 | c.391_393delACCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
| delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
| embB | 4247580 | p.Ala356Val | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
| embB | 4247663 | p.Tyr384Asn | missense_variant | 1.0 | ethambutol | Mutation from literature | |
| embB | 4247676 | p.Ala388Gly | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 1035 | c.1035A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1051 | c.1051_1053delCTCinsTG | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| dnaA | 1059 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1077 | c.1077A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1113 | c.1113A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1122 | c.1122C>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1125 | c.1125G>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1128 | c.1128G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1149 | c.1149C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1153 | c.1153T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1161 | c.1161A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1164 | c.1164A>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1167 | c.1167A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1176 | c.1176A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1203 | c.1203T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1210 | p.Ala404Ser | missense_variant | 1.0 | isoniazid | |
| dnaA | 1220 | p.Asn407Ser | missense_variant | 1.0 | isoniazid | |
| dnaA | 1236 | c.1236C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1254 | c.1254T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1278 | c.1278T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1284 | c.1284C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1293 | c.1293T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1299 | c.1299G>C | synonymous_variant | 0.94 | isoniazid | Not assoc w R - Interim |
| dnaA | 1302 | c.1302C>G | synonymous_variant | 0.94 | isoniazid | |
| dnaA | 1314 | c.1314A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1317 | c.1317A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1323 | c.1323C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1335 | c.1335G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1338 | c.1338T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1341 | c.1341G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1347 | c.1347C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1353 | c.1353T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1356 | c.1356T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1359 | c.1359G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1368 | c.1368T>C | synonymous_variant | 1.0 | isoniazid | |
| gyrB | 6070 | c.831C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6073 | c.834T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6084 | c.846delC | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 6091 | c.853dupC | frameshift_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrB | 6100 | c.861G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6103 | c.864G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6121 | c.882C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6130 | c.891T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6209 | c.970C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6223 | c.984G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6229 | c.990G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6247 | c.1008G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6250 | c.1011A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6262 | c.1023G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6304 | c.-998C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6310 | c.-992G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6313 | c.-989C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6316 | c.-986G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 6337 | c.1098G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6355 | c.-947G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6403 | c.-899T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6415 | c.-887G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6676 | c.-626T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6685 | c.1446C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6772 | c.1533C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6778 | c.-524C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6805 | c.1566G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6808 | c.1569C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6850 | c.-452C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6869 | c.-433T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6878 | c.1639T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6881 | c.1642T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6901 | c.-401G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6902 | c.1663_1665delCTCinsTG | frameshift_variant&missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | ||||||
| gyrA | 6910 | c.-392G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6913 | c.1674C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6919 | c.1680T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6931 | c.1692A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6943 | c.-359G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6952 | c.1713C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6970 | c.-332C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6973 | c.-329G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6994 | c.-308C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7006 | c.-296T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7010 | c.-292C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7021 | c.-281G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7033 | c.-269G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7078 | c.-224A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7081 | c.-221T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7412 | c.111C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7499 | c.198G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7520 | c.219G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7559 | c.258G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7565 | c.264C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7577 | c.276C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7760 | c.459C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7784 | c.483A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7832 | c.531G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8321 | c.1020C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8342 | c.1041G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8360 | c.1059G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8399 | c.1098T>C | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8402 | p.Asp367Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8423 | c.1122G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8438 | c.1137C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8459 | c.1158G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8468 | c.1167C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8510 | c.1209G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8537 | c.1236G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8555 | c.1254G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8573 | c.1272G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8595 | p.Ala432Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8603 | c.1302A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8618 | c.1317G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8633 | c.1332C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8637 | c.1336C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8684 | c.1383G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8717 | c.1416C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8738 | c.1437G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8740 | p.Arg480His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8751 | p.Ala484Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8783 | c.1482G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8796 | p.Ile499Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8816 | c.1515C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8828 | c.1527T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8939 | c.1638T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8946 | c.1645T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8954 | c.1653G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8965 | c.1664_1665insG | frameshift_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8968 | c.1668delG | frameshift_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8981 | c.1680G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 0.95 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9056 | c.1755C>G | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9062 | c.1761C>T | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9074 | c.1773G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9104 | c.1803C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9119 | c.1818A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9131 | c.1830G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9134 | c.1833C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9153 | p.Thr618Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9167 | c.1866C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9175 | p.Leu625Pro | missense_variant | 0.7 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9179 | c.1878C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9188 | c.1887C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9191 | c.1890G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9218 | c.1917C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9251 | c.1950G>C | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 0.97 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9257 | c.1956C>T | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9275 | c.1974G>A | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9276 | c.1975C>T | synonymous_variant | 0.96 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9299 | c.1998G>A | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9300 | c.1999_2001delGCCinsTG | frameshift_variant&missense_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9335 | c.2034G>T | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9344 | c.2043C>T | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 490777 | c.-6G>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490781 | c.-2T>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490794 | c.12G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490797 | c.15G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490800 | c.18A>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 490803 | c.21T>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490806 | c.24C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490812 | c.30A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490815 | c.33G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490851 | c.69A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490868 | p.Ala29Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490887 | c.105G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490896 | c.114C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490902 | c.120T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490911 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490917 | c.135C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490926 | c.144C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490962 | c.180T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 490998 | c.216T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491022 | c.240C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491031 | c.249C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491038 | p.Ile86Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491063 | p.Gly94Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491082 | c.300T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491091 | c.309T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491137 | p.Glu119Gln | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491144 | p.Ala121Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491169 | c.387C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491219 | p.Asp146Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491226 | c.444C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491229 | c.447C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491283 | p.Asp167Glu | missense_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491292 | c.510G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491295 | c.513C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fgd1 | 491296 | p.Val172Ile | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491302 | p.Ile174Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491331 | c.549G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491340 | c.558C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491343 | c.561C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491349 | c.567T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491355 | c.573C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491391 | c.609C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491393 | p.Thr204Lys | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491397 | p.Glu205Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491415 | c.633A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491418 | c.636A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491421 | c.639A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491430 | c.648T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491436 | c.654T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491442 | c.660A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491443 | p.Ser221Asn | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491453 | p.Gly224Asp | missense_variant | 1.0 | clofazimine | Uncertain significance |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fgd1 | 491472 | c.690A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491493 | c.711C>G | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491496 | c.714C>T | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491499 | c.717G>T | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491508 | c.726A>G | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491509 | c.727T>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491517 | c.735C>T | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491526 | c.744T>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491542 | c.760T>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491547 | c.765A>C | synonymous_variant | 0.93 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491550 | c.768T>C | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491559 | c.777G>A | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491574 | c.792C>T | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491583 | c.801G>A | synonymous_variant | 0.94 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491610 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491620 | p.Ile280Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491640 | c.858G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491658 | c.876A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491661 | c.879C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491673 | c.891A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491679 | c.897A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fgd1 | 491686 | p.Thr302Glu | missense_variant | 0.9 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| mshA | 574640 | c.-708G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 574650 | c.-698A>C | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| mshA | 574664 | c.-684G>C | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| mshA | 574673 | c.-675A>G | upstream_gene_variant | 0.92 | ethionamide | |
| isoniazid | ||||||
| mshA | 574679 | c.-669C>T | upstream_gene_variant | 0.87 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 574683 | c.-665T>C | upstream_gene_variant | 0.88 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574688 | c.-660G>C | upstream_gene_variant | 0.88 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 574694 | c.-654C>G | upstream_gene_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| mshA | 574712 | c.-636A>G | upstream_gene_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| mshA | 574718 | c.-630A>G | upstream_gene_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| mshA | 574724 | c.-624T>C | upstream_gene_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| mshA | 574731 | c.-617A>G | upstream_gene_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| mshA | 574739 | c.-609T>C | upstream_gene_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| mshA | 574742 | c.-606G>A | upstream_gene_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| mshA | 574763 | c.-585T>C | upstream_gene_variant | 0.89 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 574782 | c.-566C>G | upstream_gene_variant | 0.83 | ethionamide | |
| isoniazid | ||||||
| mshA | 574792 | c.-556_-555delTCinsCG | upstream_gene_variant | 0.8 | ethionamide | |
| isoniazid | ||||||
| mshA | 575042 | c.-306T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575051 | c.-297A>G | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 575052 | c.-296G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575060 | c.-288G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575063 | c.-285T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575072 | c.-276G>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575075 | c.-273T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| mshA | 575084 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575087 | c.-261C>G | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575102 | c.-246G>A | upstream_gene_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575512 | c.165A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575521 | c.174A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575530 | c.183C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575536 | c.189T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575542 | c.195C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575560 | c.213C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575561 | p.Met72Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575571 | p.Ser75Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575587 | c.240C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575590 | c.243T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575629 | c.282A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575632 | c.285G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575635 | c.288A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575641 | c.294A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575647 | c.300G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575649 | p.Val101Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575659 | c.312A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575665 | c.318G>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575689 | c.342G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575695 | c.348C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575704 | c.357T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575779 | c.432A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575785 | c.438T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575786 | p.Tyr147His | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575824 | c.477T>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575875 | c.528C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575887 | c.540G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575896 | c.549G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575908 | c.561A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575920 | c.573C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575944 | c.597T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575950 | c.603C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575965 | c.618C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| mshA | 575977 | c.630G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575980 | c.633T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575984 | c.637T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 575992 | c.645C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576001 | c.654C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576007 | c.660A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576012 | p.Arg222Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576017 | p.Val224Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576026 | c.679_681delCTTinsAC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| mshA | 576032 | p.Gly229His | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576046 | c.699A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576049 | c.702A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576070 | c.723T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| mshA | 576077 | c.730C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R | |||||
| ccsA | 620133 | c.243G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620139 | c.249C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620145 | c.255T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620160 | c.270A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620167 | p.Ala93Thr | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620170 | p.Cys94Ser | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620173 | p.Val95Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620187 | c.297C>G | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620198 | p.Gln103Leu | missense_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620256 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620257 | p.Ile123Leu | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620269 | p.Val127Ile | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620275 | c.385C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620283 | c.393T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620284 | p.Ala132Pro | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620288 | p.Arg133Gln | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620295 | c.405G>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620307 | c.417C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620319 | c.429C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620352 | c.462C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620361 | c.471C>T | synonymous_variant | 0.97 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620367 | c.477T>C | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620373 | c.483C>G | synonymous_variant | 0.96 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620385 | c.495G>C | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620388 | c.498A>G | synonymous_variant | 0.95 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620409 | c.519C>G | synonymous_variant | 0.94 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620415 | c.525T>C | synonymous_variant | 0.93 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620433 | c.543C>G | synonymous_variant | 0.91 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620631 | c.741T>C | synonymous_variant | 0.8 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620659 | c.769_771delCGCinsAG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620664 | c.774C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620710 | c.820_822delGTGinsAC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620715 | c.825C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620742 | c.852G>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620748 | c.858T>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620758 | c.868_870delCGCinsAG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620766 | c.876C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620769 | c.879C>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620784 | c.894C>G | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620787 | c.897C>A | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| kanamycin | ||||||
| ccsA | 620808 | c.918T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| amikacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| Rv0565c | 656304 | c.1167T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656358 | c.1113T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656364 | c.1107T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656367 | c.1104G>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656370 | c.1101T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656380 | p.Glu364Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656391 | c.1078_1080delCTCinsAG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656396 | p.Ser359Gly | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656403 | c.1068C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656412 | c.1059T>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656418 | c.1053A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656423 | c.1048T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656447 | p.Ile342Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656448 | c.1023T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656454 | c.1017G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656457 | c.1014T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656469 | c.1002T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656476 | p.Lys332Ala | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656481 | c.990A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656484 | c.987T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656487 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656502 | c.969C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 656511 | c.960T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 656539 | p.Ser311Asp | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656542 | p.Thr310Ser | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 656546 | p.Ile309Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 656924 | p.Ile183Val | missense_variant | 0.93 | ethionamide | |
| Rv0565c | 656926 | p.Lys182Arg | missense_variant | 0.93 | ethionamide | |
| Rv0565c | 657303 | c.168C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657317 | c.154C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657324 | c.147C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657342 | c.129T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657347 | c.124A>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657348 | c.123A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657369 | c.100_102delCAGinsGC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657381 | c.90A>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657385 | p.Ile29Ser | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 732130 | c.201C>G | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732133 | c.204G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732134 | p.Ala69Ser | missense_variant | 1.0 | isoniazid | |
| hadA | 732151 | c.222T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732154 | c.225G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732164 | p.Thr79Val | missense_variant | 1.0 | isoniazid | |
| hadA | 732167 | p.Ala80Thr | missense_variant | 1.0 | isoniazid | |
| hadA | 732172 | p.Glu81Asp | missense_variant | 1.0 | isoniazid | |
| hadA | 732173 | p.Ala82Gln | missense_variant | 1.0 | isoniazid | |
| hadA | 732190 | c.261A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732209 | p.Glu94Gln | missense_variant | 1.0 | isoniazid | |
| hadA | 732214 | c.285A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| hadA | 732234 | p.Lys102Arg | missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732238 | c.309G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732250 | c.321C>G | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732253 | c.324T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732259 | c.330T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732279 | p.Gly117Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732319 | c.390G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732328 | p.Asp133Glu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732329 | c.400_402delCTCinsAT | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| hadA | 732334 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732369 | p.Gly147Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732389 | p.Ser154Thr | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
| nusG | 734129 | c.-125G>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734147 | c.-107T>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734156 | c.-98C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734173 | c.-81C>G | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734175 | c.-79_-77delGGTinsCTC | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734180 | c.-74T>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734183 | c.-71C>T | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734186 | c.-68G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| nusG | 734193 | c.-61A>G | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734205 | c.-49A>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734224 | c.-30_-26delGCTCGinsCATTGC | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734233 | c.-21T>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734236 | c.-18C>T | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734370 | c.117A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734409 | c.156T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734460 | c.207G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734466 | c.213G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734470 | c.217_219delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734502 | c.249G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734566 | c.313C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734595 | c.342C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734610 | c.357C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734625 | c.372T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734640 | c.387C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734643 | c.390G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734652 | c.399T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734655 | c.402G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734658 | c.405A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| nusG | 734661 | c.408A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734664 | c.411T>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734673 | c.420A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734676 | c.423G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734679 | c.426C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734680 | c.427_429delGCCinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734703 | c.450T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734709 | c.456T>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734715 | c.462G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734717 | p.Gly155Ala | missense_variant | 1.0 | rifampicin | |
| nusG | 734719 | c.466_468delTCGinsGC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| nusG | 734726 | p.Arg158Lys | missense_variant | 1.0 | rifampicin | |
| nusG | 734733 | c.480T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734757 | c.504T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734762 | p.Ala170Val | missense_variant | 1.0 | rifampicin | |
| nusG | 734764 | p.Ala171Thr | missense_variant | 1.0 | rifampicin | |
| nusG | 734781 | c.528A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734784 | c.531G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734792 | p.Val180Ala | missense_variant | 1.0 | rifampicin | |
| nusG | 734800 | p.Val183Ile | missense_variant | 1.0 | rifampicin | |
| nusG | 734814 | c.561G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734826 | c.573A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734841 | c.588G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734865 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734870 | p.Ser206Asn | missense_variant | 1.0 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734913 | c.660C>G | synonymous_variant | 0.93 | rifampicin | |
| nusG | 734931 | c.678A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 759606 | c.-201T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759647 | c.-160T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759656 | c.-151A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759657 | c.-150G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759659 | c.-148T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759665 | c.-141delT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759671 | c.-136G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759672 | c.-135G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759681 | c.-125_-124delGT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759715 | c.-92_-91delGAinsT | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759726 | c.-81A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759732 | c.-75C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759741 | c.-66_-65insA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 759748 | c.-59_-58insC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760073 | c.267G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760091 | c.285G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760101 | c.295T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760106 | c.300G>T | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760115 | c.309C>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R |
| rpoB | 760118 | c.312T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 0.95 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 760172 | c.366G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760181 | c.375T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760184 | c.378A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760223 | c.417T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760283 | c.477G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760307 | c.501T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760313 | c.507G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 760361 | c.555T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 0.95 | rifampicin | Uncertain significance |
| rpoB | 760424 | c.618C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760454 | c.648C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760514 | c.708C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760528 | p.Gln241Arg | missense_variant | 0.97 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 0.97 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 0.97 | rifampicin | Uncertain significance |
| rpoB | 760591 | p.Val262Ala | missense_variant | 0.96 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoB | 760646 | c.840C>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760845 | c.1039_1041delACCinsGA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 760856 | c.1050C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760862 | c.1056G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760934 | c.1128C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760958 | c.1152G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761133 | c.1327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761150 | c.1344A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761171 | c.1365C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761180 | c.1374A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761196 | c.1390C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761207 | c.1401C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761273 | c.1467T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761309 | c.1503C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761333 | c.1527G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761336 | c.1530C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761339 | c.1533C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761345 | c.1539G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761348 | c.1542C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761357 | c.1551G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761375 | c.1569G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761505 | c.1699_1701delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761540 | c.1734C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761552 | c.1746G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761720 | c.1915_1916delGA | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 761724 | p.Glu640Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761728 | c.1923_1924insCC | frameshift_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761819 | c.2013G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761840 | c.2034C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 0.97 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761876 | c.2070C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761906 | c.2100C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761913 | c.2107_2109delGACinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761921 | c.2115C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761948 | c.2142G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761969 | c.2163G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762011 | c.2205G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762020 | c.2214G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762023 | c.2217C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762029 | c.2223C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762119 | c.2313C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762149 | c.2343G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762218 | c.2412T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762297 | c.2491C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762490 | p.Val895Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 762521 | c.-849C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762729 | p.Gln975Lys | missense_variant | 0.8 | rifampicin | |
| rpoC | 762734 | c.-636G>A | upstream_gene_variant | 0.8 | rifampicin | |
| rpoB | 762736 | p.Ala977Glu | missense_variant | 0.8 | rifampicin | |
| rpoB | 762753 | c.2947T>C | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| rpoC | 762758 | c.-612G>C | upstream_gene_variant | 0.86 | rifampicin | |
| rpoB | 762760 | p.Cys985Ser | missense_variant | 0.86 | rifampicin | Uncertain significance |
| rpoC | 762770 | c.-600C>G | upstream_gene_variant | 0.94 | rifampicin | |
| rpoB | 762785 | p.Asp993Glu | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 0.96 | rifampicin | |
| rpoB | 762799 | p.Ala998Gly | missense_variant | 0.96 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | p.Met1003Val | missense_variant | 0.97 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762836 | c.3030C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763052 | c.-318G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763076 | c.-294C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763082 | c.-288C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763094 | c.3288G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763184 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763202 | c.-168A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763268 | c.-102C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763408 | c.39T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763430 | c.61A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763441 | c.72C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763537 | c.168C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763573 | c.204G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763600 | c.231C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763648 | c.279C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763666 | c.297G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763708 | c.339G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763714 | c.345G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763768 | c.399C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763790 | c.421_423delGAGinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763813 | c.444C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763816 | c.447C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
| rpoC | 763851 | p.Ala161Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 763855 | c.486C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763871 | p.Gly168Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763927 | c.558C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763948 | c.579G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763963 | c.594C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763978 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764071 | c.702G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764110 | c.741C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764203 | c.834G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764206 | p.Asp279Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 764217 | p.Asn283Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 764245 | c.876C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764257 | c.888G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764269 | c.900G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764272 | c.903G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764338 | c.969G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764339 | c.970C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764429 | c.1060C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764438 | c.1069_1071delCTGinsTA | frameshift_variant&stop_gained | 1.0 | rifampicin | |
| rpoC | 764443 | c.1074C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764455 | c.1086G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764467 | c.1098C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764533 | c.1164C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764551 | c.1182G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764581 | c.1212T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764651 | c.1282_1284delTCGinsAGC | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764656 | c.1287C>T | synonymous_variant | 0.93 | rifampicin | |
| rpoC | 764695 | c.1326T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764749 | c.1380G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764830 | c.1461C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764851 | c.1482C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764858 | c.1489_1491delTTGinsCA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764861 | c.1492C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764867 | c.1498_1500delCGCinsAG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764875 | c.1506C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764878 | c.1509C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764881 | c.1512G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764885 | c.1516_1518delCGGinsAA | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 764893 | c.1524T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764983 | c.1614T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764986 | c.1617C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 765006 | c.1638_1642delTTTGA | frameshift_variant | 1.0 | rifampicin | |
| rpoC | 765013 | c.1644_1645insTCTCG | frameshift_variant | 1.0 | rifampicin | |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765052 | c.1683C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765079 | c.1710T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765247 | c.1878C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765278 | c.1909C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765292 | c.1923G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765307 | c.1938C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765326 | p.His653Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765346 | c.1977C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765349 | c.1980T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765583 | c.2214G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765612 | p.His748Arg | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765673 | p.Asp768Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765787 | c.2418C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765823 | c.2454C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765934 | c.2565C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765985 | c.2616C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766009 | c.2640G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766027 | c.2658G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766054 | c.2685C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766063 | c.2694C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766081 | c.2712T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766084 | c.2715A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766085 | p.Pro906Ala | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766141 | c.2772C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766142 | c.2773C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766148 | p.Thr927Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766168 | c.2799C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766178 | p.Ile937Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 766185 | p.Glu939Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 766189 | c.2820T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766193 | c.2824_2826delCAAinsGG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoC | 766204 | c.2835C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766207 | c.2838T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766211 | p.Glu948Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 766216 | c.2847T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766222 | c.2853T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766231 | c.2862T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766234 | c.2865T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766237 | c.2868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766240 | c.2871T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766243 | c.2874C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766258 | c.2889T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766270 | c.2901G>C | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 766274 | p.Ala969Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 766280 | p.Ser971Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766285 | c.2916C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766312 | c.2943T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766345 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766447 | c.3078T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766486 | c.3117A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766504 | c.3135G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766531 | c.3162G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766540 | p.Asp1057Glu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766582 | c.3213C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766591 | c.3222A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766597 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 766627 | c.3258G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766658 | p.Arg1097Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766861 | c.3492G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766915 | p.Asp1182Glu | missense_variant | 0.96 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766923 | p.Glu1185Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 766931 | c.3562_3564delGCAinsTG | frameshift_variant&stop_gained | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766978 | c.3609C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767032 | c.3663G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767152 | c.3783T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767158 | c.3789T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767188 | c.3819G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767242 | p.Gln1291His | missense_variant | 1.0 | rifampicin | |
| rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781608 | c.49_51delAGTinsGC | frameshift_variant&missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781628 | c.69T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781682 | c.123T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781709 | c.150G>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781820 | c.261G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781835 | c.276T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800576 | c.-233C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800600 | c.-209G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800684 | c.-125G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800690 | c.-119C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800799 | c.-10_-8delGGAinsC | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800874 | c.66A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800880 | c.72A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800889 | c.81C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800907 | c.99C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800967 | c.159C>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800970 | c.162T>C | synonymous_variant | 0.97 | linezolid | Not assoc w R - Interim |
| rplC | 800973 | c.165C>T | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
| rplC | 800982 | c.174C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800985 | c.177A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801004 | p.Leu66Val | missense_variant | 1.0 | linezolid | |
| rplC | 801009 | c.201A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801027 | c.219C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801039 | c.231A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801045 | c.237A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801134 | p.Gly109Ala | missense_variant | 1.0 | linezolid | |
| rplC | 801137 | p.Ser110Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801147 | c.339T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801153 | c.345G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801171 | c.363A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801174 | c.366T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801201 | c.393C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801222 | c.414T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801264 | c.456C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801267 | c.459A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801270 | c.462T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801276 | c.468G>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801288 | c.480G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801315 | c.507G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801339 | c.531T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
| rplC | 801396 | c.588T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801400 | c.592_594delGTTinsAC | frameshift_variant&missense_variant | 1.0 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801426 | c.618C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801432 | c.624C>G | synonymous_variant | 1.0 | linezolid | |
| fbiC | 1303268 | p.Lys113Arg | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303272 | c.342A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303275 | c.345C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303281 | c.351A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303285 | p.Ser119Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303288 | p.Ser120Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303292 | p.Thr121Met | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303297 | p.Met123Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303332 | c.402A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303335 | c.405T>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303464 | c.534A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303480 | p.Gln184Glu | missense_variant | 0.91 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303492 | c.562T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303501 | c.571C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303614 | c.684C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303623 | c.693C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303638 | c.708A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303660 | p.Val244Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303695 | c.765T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303731 | c.801A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303732 | p.Ser268Pro | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303749 | c.819G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303752 | c.822A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303755 | c.825T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303789 | p.Ile287Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303794 | c.864A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303809 | c.879G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303818 | c.888C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303821 | c.891C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303854 | c.924T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303860 | c.930A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303869 | c.939T>C | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1303884 | c.954T>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303905 | c.975G>C | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303920 | c.990C>G | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303935 | c.1005G>A | synonymous_variant | 0.98 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303947 | c.1017T>C | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303956 | c.1026A>G | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303961 | p.Arg344Leu | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303965 | c.1035G>A | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303969 | p.Val347Ile | missense_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303989 | c.1059C>T | synonymous_variant | 0.97 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1303998 | c.1068T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304001 | c.1071C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304004 | c.1074A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304022 | c.1092T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304031 | c.1101C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304058 | p.Glu376Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304067 | c.1137G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304070 | c.1140C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304091 | p.Asp387Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304096 | p.Val389Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304115 | c.1185A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304127 | c.1197A>C | synonymous_variant | 0.96 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304133 | c.1203G>C | synonymous_variant | 0.92 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304136 | c.1206C>G | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304169 | c.1239T>C | synonymous_variant | 0.96 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304172 | c.1242G>T | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304184 | c.1254G>C | synonymous_variant | 0.95 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304199 | c.1269C>G | synonymous_variant | 0.88 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304205 | c.1275C>T | synonymous_variant | 0.86 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304232 | c.1302G>C | synonymous_variant | 0.82 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304607 | c.1677C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304637 | c.1707G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304671 | p.Val581Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304675 | p.Gly582Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304691 | c.1761G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304694 | c.1764A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304724 | c.1794A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1304727 | c.1797A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304742 | c.1812T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304748 | c.1818T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304757 | c.1827A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304778 | c.1848T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304784 | c.1854T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304787 | c.1857T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304799 | c.1869G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304808 | c.1878C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304823 | c.1893C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304853 | c.1923C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304869 | c.1939C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304883 | p.Glu651Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304910 | c.1980G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304913 | c.1983G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304916 | c.1986T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304925 | c.1995G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304940 | c.2010A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304970 | c.2040G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304976 | c.2046G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304983 | c.2053C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1304995 | c.2065T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305021 | c.2091C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305033 | c.2103T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305042 | c.2112A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305045 | c.2115A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305066 | c.2136T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305069 | c.2139G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305074 | p.Ser715Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305078 | c.2148A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305090 | c.2160C>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305096 | c.2166T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305099 | c.2169T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305114 | p.Asp728Glu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305117 | c.2187T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305126 | c.2196T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiC | 1305135 | c.2205C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305150 | c.2220C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305154 | c.2224T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305159 | c.2229G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305177 | c.2247A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305181 | c.2251T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305186 | c.2256C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305195 | c.2265T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305201 | c.2271G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305204 | c.2274C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305215 | p.Ser762Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305228 | c.2298C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305231 | c.2301C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305237 | c.2307A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305243 | c.2313T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305244 | c.2314T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305273 | c.2343C>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305276 | c.2346G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305282 | c.2352T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305297 | c.2367G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiC | 1305343 | p.Asn805Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| sigE | 1364661 | c.249C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364667 | c.255T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364676 | c.264C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364691 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364712 | c.300T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364766 | c.354C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364772 | c.360G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364796 | c.384G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364799 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364802 | c.390C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364805 | c.393C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364808 | c.396C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364811 | c.399A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364814 | c.402C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364838 | c.426C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364847 | c.435G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364898 | c.486C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364910 | c.498G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364952 | c.540A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364958 | c.546G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364961 | c.549A>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364962 | c.550_552delCCTinsGC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| sigE | 1364968 | c.556C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364976 | c.564T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364980 | c.568T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364984 | p.Ala191Asp | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364989 | c.577C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1365006 | c.594T>C | synonymous_variant | 0.95 | pyrazinamide | |
| sigE | 1365012 | c.600G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365015 | c.603G>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365033 | c.621G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365036 | c.624T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1365042 | c.630G>C | synonymous_variant | 1.0 | pyrazinamide | |
| atpE | 1460813 | c.-232C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460816 | c.-229T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460828 | c.-217C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460831 | c.-214T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460832 | c.-213C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460837 | c.-208C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460840 | c.-205A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1461068 | c.24C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461097 | p.Ala18Gly | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461101 | c.57T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461107 | c.63C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461119 | c.75T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
| atpE | 1461137 | c.93C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461150 | c.106_108delATCinsGT | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| atpE | 1461155 | c.111C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461159 | p.Val39Ile | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| atpE | 1461182 | c.138A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461189 | c.145C>T | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461197 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461212 | c.168C>G | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
| atpE | 1461224 | c.180T>C | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471508 | n.-338T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472019 | n.174G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472028 | n.183A>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472040 | n.195T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472045 | n.200T>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Not assoc w R | |||||
| rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474040 | n.383G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474060 | n.403G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474089 | n.432C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474249 | n.592G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474289 | n.632C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474292 | n.635T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474293 | n.637_651delCCTCTCCGGAGGAGG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474552 | n.895C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474950 | n.1293G>A | non_coding_transcript_exon_variant | 0.93 | capreomycin | |
| linezolid | ||||||
| rrl | 1474952 | n.1296_1300delCATCC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474961 | n.1304T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474962 | n.1305T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474963 | n.1306G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474964 | n.1307T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474967 | n.1311_1315delGGGTG | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474997 | n.1340A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475006 | n.1349A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475213 | n.1556C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1475253 | n.1596T>G | non_coding_transcript_exon_variant | 0.95 | capreomycin | |
| linezolid | ||||||
| rrl | 1475273 | n.1616T>G | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1475276 | n.1619T>C | non_coding_transcript_exon_variant | 0.94 | capreomycin | |
| linezolid | ||||||
| rrl | 1475289 | n.1632G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475363 | n.1706C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475366 | n.1709G>A | non_coding_transcript_exon_variant | 0.96 | capreomycin | |
| linezolid | ||||||
| rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475409 | n.1752T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475532 | n.1875A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475606 | n.1949T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475616 | n.1959A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475617 | n.1960C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475625 | n.1968G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475626 | n.1969T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475639 | n.1982C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475655 | n.1998T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475883 | n.2226A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476035 | n.2378G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476103 | n.2446C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476105 | n.2448G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476106 | n.2449A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476110 | n.2453G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476256 | n.2599A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476583 | n.2926G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1674237 | c.36T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674239 | p.Ser13Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674243 | c.42A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674249 | c.48C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674279 | c.78A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674285 | c.84A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674300 | c.99C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674304 | c.103_105delCAGinsGA | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674315 | c.114C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674342 | c.141T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674352 | p.Thr51Ala | missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | ||||||
| inhA | 1674364 | c.164_165dupCG | frameshift_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674368 | c.169_170delAA | frameshift_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674387 | c.186A>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674406 | p.Glu69Lys | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674416 | p.Ala72Asp | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674419 | p.Ser73Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674421 | c.220_222delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674425 | p.Ala75Gly | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674428 | p.Gly76Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674443 | p.Ala81Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674450 | c.249G>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674452 | p.Ala84Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674471 | c.270G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674486 | c.285T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674489 | c.288G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674503 | p.Thr101Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674550 | p.Ser117Ala | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674570 | c.369G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674576 | c.375T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674628 | p.Ser143Gly | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674654 | c.453G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674660 | c.459G>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674663 | c.462G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674714 | c.513C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674726 | c.525G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674729 | c.528G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674750 | c.549T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674765 | c.564C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674771 | c.570C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674777 | c.576C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674792 | c.591G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674816 | c.615T>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674825 | c.624C>T | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | Not assoc w R - Interim | |||||
| inhA | 1674846 | c.645C>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674849 | p.Gln216His | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674876 | c.675C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674879 | c.678T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674883 | c.682_684delATCinsCG | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674903 | c.702T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674904 | c.703_705delGCGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674933 | c.732G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674939 | c.738G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674942 | c.741T>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674945 | p.Asp248Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674957 | c.756G>A | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674966 | c.765T>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674967 | p.Asp256Thr | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674970 | p.Ile257Val | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674993 | c.792G>C | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674994 | p.His265Ser | missense_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| rpsA | 1833256 | c.-286C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833265 | c.-277A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833268 | c.-274C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833271 | c.-271G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833273 | c.-269G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833280 | c.-262G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833283 | c.-259C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833295 | c.-247C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833331 | c.-211G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833517 | c.-24delC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833541 | c.-1T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833554 | p.Thr5Ala | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1833578 | p.Val13Ile | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833613 | c.72C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833625 | c.84A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833673 | c.132C>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833742 | c.201A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833787 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833817 | c.276C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833859 | c.318C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833971 | c.430C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834009 | c.468C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834012 | c.471G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834051 | c.510G>A | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834099 | c.558C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834108 | c.567C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834189 | c.648G>C | synonymous_variant | 0.9 | pyrazinamide | |
| rpsA | 1834192 | c.651C>G | synonymous_variant | 0.9 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834262 | c.721_723delTCGinsAGT | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834378 | c.837T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834417 | c.876G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834474 | c.933C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834528 | c.987T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834606 | c.1065C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834619 | c.1078T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834654 | p.Glu371Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834696 | c.1155C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834733 | p.Ala398Ser | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834747 | c.1206A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834751 | c.1210_1212delCTTinsTG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834788 | p.Ala416Gly | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834852 | c.1311C>G | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853360 | c.-246G>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 0.97 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853441 | c.-165C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853444 | c.-162C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853447 | c.-159C>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853450 | c.-156G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853459 | c.-147G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853462 | c.-144A>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853468 | c.-138C>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853477 | c.-129T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853485 | c.-121G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853489 | c.-117C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853492 | c.-114G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853498 | c.-108G>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853928 | p.Gln108Arg | missense_variant | 1.0 | linezolid | |
| tsnR | 1853941 | c.336G>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853942 | p.Thr113Ala | missense_variant | 1.0 | linezolid | |
| tsnR | 1853954 | p.Arg117Gly | missense_variant | 1.0 | linezolid | |
| tsnR | 1853968 | c.363C>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853971 | c.366G>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1853978 | c.373_375delGTAinsCG | frameshift_variant&missense_variant | 1.0 | linezolid | Uncertain significance |
| tsnR | 1854004 | c.399T>C | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1854007 | c.402C>G | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1854024 | p.Ala140Gly | missense_variant | 1.0 | linezolid | |
| tsnR | 1854030 | p.Arg142His | missense_variant | 1.0 | linezolid | |
| tsnR | 1854034 | c.429C>T | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1854043 | c.438A>G | synonymous_variant | 1.0 | linezolid | |
| tsnR | 1854058 | c.453T>C | synonymous_variant | 1.0 | linezolid | |
| bacA | 2064189 | c.540G>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064192 | c.535_537delGAAinsAC | frameshift_variant&missense_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| bacA | 2064207 | c.522C>T | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064210 | c.519A>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064223 | p.Arg169Lys | missense_variant | 1.0 | streptomycin | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| bacA | 2064240 | c.487_489delCAAinsGC | frameshift_variant&missense_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| bacA | 2064243 | c.486A>C | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064251 | p.His160Asn | missense_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064253 | p.His159Ala | missense_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064258 | c.471A>G | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064267 | c.460_462delAGGinsCC | frameshift_variant&missense_variant | 1.0 | streptomycin | Uncertain significance |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| bacA | 2064281 | p.Ile150Val | missense_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064285 | c.444C>A | synonymous_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064915 | c.-187G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064927 | c.-199G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064932 | c.-204C>T | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064936 | c.-208C>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064948 | c.-220G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064952 | c.-224T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064969 | c.-241T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064972 | c.-244T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064978 | c.-250G>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064979 | c.-253_-251delGGCinsCT | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064984 | c.-256A>G | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2064993 | c.-265T>C | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| bacA | 2065005 | c.-277C>T | upstream_gene_variant | 1.0 | streptomycin | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| ndh | 2101711 | c.1332G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101726 | c.1317A>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101732 | c.1311T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101735 | c.1308A>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101768 | c.1275C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101771 | c.1272T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101774 | c.1269T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101777 | c.1266C>G | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101783 | c.1260T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101795 | c.1248G>C | synonymous_variant | 0.98 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101804 | c.1239T>G | synonymous_variant | 0.98 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101838 | p.Ala402Val | missense_variant | 0.99 | ethionamide | Uncertain significance |
| delamanid | ||||||
| isoniazid | Uncertain significance | |||||
| ndh | 2101858 | p.Ile395Met | missense_variant | 0.99 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101873 | c.1170T>C | synonymous_variant | 0.98 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101888 | c.1153_1155delGTTinsCG | frameshift_variant&missense_variant | 0.98 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2101891 | c.1152C>G | synonymous_variant | 0.98 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2101912 | c.1131G>C | synonymous_variant | 0.98 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101920 | c.1123A>C | synonymous_variant | 0.99 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101924 | c.1119T>G | synonymous_variant | 0.99 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101936 | c.1107G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101939 | c.1104A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101960 | c.1083A>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101970 | p.Glu358Ala | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101980 | p.Asn355Asp | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101984 | c.1059C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101988 | p.Ala352Gly | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2101990 | c.1053G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102009 | p.Ser345Asn | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102020 | c.1023A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102023 | c.1020G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102026 | c.1017G>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102050 | c.993T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102059 | c.984T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102065 | c.978G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102068 | c.975T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102077 | c.966T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102083 | c.960G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102086 | c.957G>C | synonymous_variant | 0.96 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102098 | c.945G>C | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102101 | c.940_942delTACinsCT | frameshift_variant&missense_variant | 0.94 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102110 | c.931_933delATTinsGC | frameshift_variant&missense_variant | 0.94 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102122 | c.921C>G | synonymous_variant | 0.95 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102131 | c.910_912delCAAinsAG | frameshift_variant&synonymous_variant | 0.95 | ethionamide | Uncertain significance |
| delamanid | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102140 | c.903C>G | synonymous_variant | 0.96 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102158 | c.885T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102162 | p.Arg294Ser | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102164 | c.879A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102167 | c.876A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102176 | c.867T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102193 | p.Arg284Gly | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102194 | c.849T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102201 | p.Ser281Gln | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102203 | c.840T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102206 | c.837G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102209 | c.834C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102212 | c.831G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102221 | c.822G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102230 | c.813G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102247 | p.Val266Ile | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102269 | c.774C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102287 | c.756C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102311 | c.732G>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102317 | c.726A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102320 | c.723G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102341 | c.702C>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102344 | c.699T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102366 | p.Ala226Glu | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Uncertain significance | |||||
| ndh | 2102377 | c.666A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102382 | c.661C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102389 | c.654G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102392 | c.651C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102401 | c.642T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102407 | c.636T>C | synonymous_variant | 0.97 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102425 | c.618G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102443 | c.600A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102446 | c.597C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102454 | c.589T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102455 | c.588G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102461 | c.582G>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102469 | c.574C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102590 | c.453A>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102593 | c.450C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102610 | c.433T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102623 | c.420C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102626 | c.417G>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102635 | c.408C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102638 | c.405A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102653 | c.390T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102668 | c.375T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102671 | c.372T>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102680 | c.363T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102683 | c.360T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102712 | p.Pro111Ser | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102718 | p.Gln109Glu | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102728 | c.315T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102737 | p.Glu102Asp | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102740 | c.303G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102743 | c.300C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102746 | c.297C>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102750 | p.Cys98Thr | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102755 | p.Gly96Asn | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102771 | p.His91Gly | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102787 | c.256T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102791 | c.252A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102800 | c.243T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102809 | c.234G>A | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102812 | c.231T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102830 | c.213G>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102842 | c.201A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102857 | c.186T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102872 | c.171A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102883 | c.160C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102884 | c.159G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102893 | c.150G>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102899 | c.144T>C | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102919 | c.124C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| delamanid | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| ndh | 2102929 | c.114T>C | synonymous_variant | 0.96 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102934 | p.Asp37Asn | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102938 | p.Arg35His | missense_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102944 | c.99C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102959 | c.84C>T | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| ndh | 2102962 | c.81A>G | synonymous_variant | 1.0 | ethionamide | |
| delamanid | ||||||
| isoniazid | ||||||
| katG | 2155590 | c.522A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155596 | c.516G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155617 | c.495T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155632 | c.480A>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155637 | p.Leu159Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155641 | p.Lys157Asn | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155676 | c.436C>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155696 | p.Ala139Val | missense_variant | 1.0 | isoniazid | |
| katG | 2155704 | c.408C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155722 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
| pncA | 2289871 | c.-630T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289874 | c.-633C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289880 | c.-639T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289906 | c.-665T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289913 | c.-672T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289916 | c.-675A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289920 | c.-679C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289940 | c.-699C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289943 | c.-702T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289948 | c.-707C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289949 | c.-708A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289961 | c.-720C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289964 | c.-723C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289970 | c.-729C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289994 | c.-753A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2289997 | c.-756G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290006 | c.-765T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290009 | c.-768A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290015 | c.-774A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290030 | c.-791_-789delAATinsCC | upstream_gene_variant | 0.97 | pyrazinamide | |
| pncA | 2290034 | c.-794_-793delGCinsAG | upstream_gene_variant | 0.97 | pyrazinamide | |
| pncA | 2290042 | c.-801T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290072 | c.-831T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290075 | c.-834C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290084 | c.-843T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290087 | c.-846T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290102 | c.-861G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290108 | c.-867C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| pncA | 2290114 | c.-873T>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| kasA | 2517956 | c.-159G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518162 | c.48G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518172 | c.58_60delACAinsGG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518195 | c.81G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518226 | p.Ala38Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2518245 | p.His44Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518279 | c.165T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518282 | c.168A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518283 | c.169_171delGCGinsCC | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518297 | c.183C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518300 | c.186T>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518312 | p.Asp66Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518316 | p.Val68Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518323 | p.Ser70Asn | missense_variant | 1.0 | isoniazid | |
| kasA | 2518475 | c.361A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518483 | c.369C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518492 | c.378C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518571 | p.Val153Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518579 | c.465T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518594 | c.480C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518603 | c.489G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518627 | c.513T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518642 | c.528A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518645 | c.531G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518657 | c.543G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518663 | c.549T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518681 | c.567C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518697 | p.Cys195Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518717 | c.603C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518795 | c.681C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518798 | c.684G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518843 | c.729T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518849 | c.735G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518855 | c.741C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518877 | p.Lys255Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518885 | c.771T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518893 | p.Lys260Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518898 | c.784T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518906 | c.792A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518907 | c.793T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518912 | c.798G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518921 | c.807T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518939 | c.825T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518942 | c.828T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518960 | c.846C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518966 | c.852T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518967 | c.853_855delGTTinsAG | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2518978 | c.864T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518990 | c.876T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518993 | c.879C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519008 | c.894C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519011 | c.897G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519012 | c.898_900delTTGinsCA | frameshift_variant&missense_variant | 1.0 | isoniazid | |
| kasA | 2519017 | c.903G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519020 | c.906G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519021 | p.Ala303Lys | missense_variant | 1.0 | isoniazid | |
| kasA | 2519026 | c.912C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519027 | p.Ile305Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2519062 | c.948T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519072 | p.Ala320Thr | missense_variant | 1.0 | isoniazid | |
| kasA | 2519077 | c.963G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519107 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519110 | p.Asp332Glu | missense_variant | 1.0 | isoniazid | |
| kasA | 2519112 | p.Gln333Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2519137 | c.1023T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519152 | c.1038G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519167 | c.1053T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519173 | c.1059C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519176 | c.1062G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519179 | c.1065G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519182 | c.1068G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519191 | c.1077G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519192 | c.1078C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519197 | c.1083G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519200 | c.1086G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519203 | c.1089C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519215 | c.1101C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519221 | c.1107G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519224 | c.1110C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519239 | c.1125A>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519263 | c.1149C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519266 | c.1152C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519272 | c.1158C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519281 | c.1167G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519287 | c.1173T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519295 | p.Tyr394Phe | missense_variant | 1.0 | isoniazid | |
| kasA | 2519299 | c.1185C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519305 | c.1191A>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519306 | p.Val398Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2519323 | c.1209G>A | synonymous_variant | 1.0 | isoniazid | |
| eis | 2715649 | c.-317C>G | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715652 | c.-320T>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715663 | c.-331C>G | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715665 | c.-333A>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715673 | c.-343_-341delCTTinsGC | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715677 | c.-346_-345delCAinsGG | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715698 | c.-366T>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715706 | c.-374G>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715709 | c.-377C>T | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715715 | c.-383G>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715718 | c.-386T>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715724 | c.-392T>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715734 | c.-402T>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715742 | c.-410T>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715748 | c.-416A>C | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715759 | c.-427G>A | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| eis | 2715760 | c.-430_-428delTCAinsCGC | upstream_gene_variant | 1.0 | amikacin | |
| kanamycin | ||||||
| ahpC | 2726348 | c.156T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726357 | c.165A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726366 | c.174G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726378 | c.186T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726397 | p.Ser69Gly | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726408 | c.216T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726432 | c.240C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726441 | c.249G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726444 | c.252G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726447 | c.255T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726453 | c.261T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726467 | p.Ala92Val | missense_variant | 1.0 | isoniazid | |
| ahpC | 2726471 | c.279T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726483 | c.291T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726493 | c.301_303delAACinsGG | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
| ahpC | 2726582 | c.390G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726591 | c.399C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726600 | c.408T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726621 | c.429G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726627 | c.435G>A | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726633 | c.441C>T | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726636 | c.444G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726639 | c.447C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726645 | c.453C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726651 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726657 | c.465A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726660 | c.468C>A | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726669 | c.477T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726681 | c.489A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726687 | c.495C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726693 | c.501C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726696 | c.504C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726699 | c.507G>A | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726705 | c.513C>T | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726717 | c.525A>C | synonymous_variant | 1.0 | isoniazid | |
| folC | 2746307 | p.Arg431Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746330 | p.Glu423Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746333 | c.1264_1266delGGCinsCG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746336 | c.1263C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746351 | c.1248C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746360 | c.1239T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746378 | c.1221G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746390 | c.1209G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746400 | p.Ser400Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746566 | p.Ala345Thr | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746584 | c.1015T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746594 | c.1005T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746609 | c.990T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746612 | c.987C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746617 | p.Ala328Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746624 | c.975C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746627 | p.Asp324Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746631 | p.Gly323Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746642 | c.957T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746657 | c.942T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746663 | c.936T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746675 | c.922_924delTCCinsGG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746678 | c.921T>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746684 | c.915C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746687 | c.910_912delCTCinsGG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746691 | p.Val303Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746714 | c.885T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746728 | c.871T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746734 | p.Ile289Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746744 | c.855T>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746759 | c.840G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746765 | c.834A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746771 | c.828A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746777 | c.822T>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746785 | p.Val272Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746791 | p.Ile270Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746793 | p.Gln269Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746795 | c.804A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746798 | c.799_801delCGGinsGC | frameshift_variant&synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746801 | c.796_798delCTAinsTG | frameshift_variant&synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746813 | c.786A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746819 | c.780T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746836 | p.Ser255Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746837 | c.762G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746857 | p.Glu248Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746957 | c.642G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746975 | c.624T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746979 | p.Ala207Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746981 | c.618T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746990 | p.Asp203Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2746999 | c.600T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747002 | c.597T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747007 | p.Ser198Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747011 | c.588G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747023 | c.576C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747032 | c.567A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747036 | p.Asn188Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747059 | c.540T>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747062 | c.537A>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747070 | p.Met177Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747074 | c.525G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747086 | c.513A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747089 | c.510G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747107 | c.492G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747110 | c.489T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747113 | c.486C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747116 | c.483G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747137 | c.462G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747302 | c.297A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747341 | c.258C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747359 | c.240C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747365 | c.234G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747371 | c.228C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747395 | c.204T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747407 | c.192T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747412 | p.Ser63Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747414 | p.Arg62Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747419 | c.180C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747442 | c.157T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747443 | c.156G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747467 | p.Asp44Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747473 | p.Arg42Lys | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747482 | c.117G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| Rv2477c | 2782393 | c.1650C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782399 | c.1644T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782405 | c.1638A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782408 | c.1635T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782414 | p.Asp543Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782420 | c.1623T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782426 | c.1617G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782432 | c.1611G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782444 | c.1599G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782475 | p.Phe523Tyr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782481 | p.Lys521Arg | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782483 | c.1560G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782501 | c.1542T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782504 | c.1539G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782522 | c.1521G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782531 | c.1512C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782537 | c.1506T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782540 | c.1503T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782555 | c.1488G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782558 | p.Ile495Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782567 | c.1476C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782587 | p.Leu486Met | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782591 | c.1452T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782594 | c.1449T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782597 | c.1446G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782606 | c.1437T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782612 | c.1431T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782615 | c.1428G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782621 | c.1422T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782633 | c.1410G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782639 | c.1404A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782651 | c.1392T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782656 | c.1387C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782675 | c.1368G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782680 | c.1363T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782684 | c.1359T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782702 | c.1341G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782705 | c.1338G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782714 | c.1329A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782720 | c.1323T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782741 | c.1302G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782744 | c.1299A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782750 | c.1293T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782822 | c.1221G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782828 | c.1215T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2782837 | c.1206C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782847 | p.Arg399Lys | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782849 | c.1194G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782861 | c.1182T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782864 | c.1179T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782867 | p.Ala392Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782879 | c.1164C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782882 | c.1161T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782913 | p.Ser377Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782927 | p.Thr372Gln | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782948 | c.1095A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782957 | c.1086A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2782969 | c.1074A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782981 | c.1062G>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2782990 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783017 | c.1026C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783020 | c.1023G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783059 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783077 | c.966T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783128 | c.915C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783134 | c.909G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783140 | c.903C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783158 | c.885A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783167 | c.876G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783179 | c.864G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783182 | c.861C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783200 | c.843G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783214 | p.Ala277Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783215 | c.828G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783221 | c.822G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783230 | c.813T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783235 | c.808T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783247 | c.796T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783254 | c.789A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783263 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783278 | c.765A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783286 | p.Ala253Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783287 | c.756C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783290 | c.753G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783299 | c.744A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783302 | c.741A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783308 | c.735G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783311 | c.732T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783329 | c.714G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783335 | c.708C>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783338 | c.705C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783341 | c.702C>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783347 | c.696C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783371 | c.672A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783395 | c.648T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783407 | c.636C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783422 | c.621T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783425 | c.618C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783432 | p.Ser204Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783440 | c.603T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783520 | c.523T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783557 | c.486T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783569 | c.474C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783593 | c.450T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783620 | c.423C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783659 | p.Glu128Asp | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783674 | c.369T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783680 | c.363G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.98 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783779 | c.264T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | c.244_246delGACinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| kanamycin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| Rv2477c | 2783815 | c.228A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | p.Asp61Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783872 | c.171G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783883 | c.160T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783884 | c.159T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783914 | c.129T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Phe | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| kanamycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2784366 | c.-324G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784375 | c.-333T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784378 | c.-336A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784381 | c.-339T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784390 | c.-348G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784396 | c.-354A>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784414 | c.-372A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784426 | c.-386_-384delTTGinsCA | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784429 | c.-387A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784432 | c.-390A>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784441 | c.-399G>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784452 | c.-410C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784454 | c.-412G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784456 | c.-414A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784465 | c.-423T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784477 | c.-435T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784501 | c.-459T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784510 | c.-470_-468delAGCinsGCG | upstream_gene_variant | 0.94 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784516 | c.-474C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784519 | c.-477G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784528 | c.-486T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| Rv2477c | 2784558 | c.-516A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| kanamycin | ||||||
| rifampicin | ||||||
| amikacin | ||||||
| pepQ | 2859306 | c.1113T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859318 | c.1101A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859432 | c.987T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859438 | c.981T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859468 | c.951G>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859471 | c.948A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859486 | c.933A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859489 | p.Val310Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859492 | c.927G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859498 | c.921C>A | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859510 | c.909T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859513 | c.906A>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859525 | c.894T>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859528 | c.891T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859534 | c.885A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859539 | c.880C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859540 | c.879A>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859546 | c.873T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859552 | p.His289Gln | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859574 | p.Ala282Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859584 | p.Gln279Lys | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859591 | c.828A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859594 | c.825T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859618 | c.801T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859623 | p.Pro266Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859625 | p.Leu265Arg | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859635 | p.Gln262Glu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859639 | c.780T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859646 | p.Gln258Arg | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859648 | c.771A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859660 | c.759G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859667 | p.Gln251Arg | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859678 | c.741A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859691 | c.727_728insGTAAGGCCG | conservative_inframe_insertion | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859704 | c.715T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859711 | c.708C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859723 | c.696T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| bedaquiline | ||||||
| pepQ | 2859732 | c.687C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859735 | c.684G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859747 | c.672C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859765 | c.654G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859778 | p.Val214Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859781 | p.Gln213Ala | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859786 | c.633G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859793 | p.Asp209Gly | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859801 | c.618G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859834 | c.585T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| pepQ | 2859852 | c.567A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859855 | c.564G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859864 | c.555T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859870 | c.549T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859873 | c.546T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859886 | p.Ala178Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859908 | p.Gln171Glu | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859909 | c.510G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859912 | c.507A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859918 | c.501A>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859921 | c.498C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859924 | c.495G>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859942 | c.477C>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859950 | c.469T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859951 | c.468C>T | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859966 | c.453T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859972 | c.447A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859975 | c.444A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859984 | c.435A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2859987 | c.432A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860001 | p.Leu140Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860344 | p.Ser25Thr | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860349 | p.Ile24Val | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860359 | c.60T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860364 | c.55T>C | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860369 | c.49_50delTCinsAG | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860375 | p.Ala15Gly | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860377 | p.Ile14Met | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860383 | c.36A>G | synonymous_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860392 | p.Lys9Asn | missense_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860446 | c.-28T>C | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860447 | c.-29A>G | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860448 | c.-30C>T | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| pepQ | 2860456 | c.-39_-38delAGinsCC | upstream_gene_variant | 1.0 | clofazimine | |
| bedaquiline | ||||||
| Rv2680 | 2996587 | c.483G>A | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| Rv2681 | 2996593 | c.-146T>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996608 | c.-131A>G | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996614 | c.-125G>A | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996617 | c.-122A>G | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996638 | p.Asp178Glu | missense_variant | 1.0 | capreomycin | |
| Rv2680 | 2996639 | c.535_537delCTGinsGC | frameshift_variant&missense_variant | 1.0 | capreomycin | Uncertain significance |
| Rv2681 | 2996644 | c.-95C>G | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996646 | p.Ala181Val | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996650 | c.-89T>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996654 | p.Gln184Lys | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996671 | c.-68C>G | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996674 | c.-65G>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996677 | c.-62G>A | upstream_gene_variant | 0.94 | capreomycin | |
| Rv2681 | 2996683 | c.-56G>C | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996686 | c.-53C>G | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996692 | c.-47G>A | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2681 | 2996698 | c.-41A>G | upstream_gene_variant | 1.0 | capreomycin | |
| Rv2680 | 2996699 | p.Ala199Thr | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996895 | p.Pro53Ser | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996900 | c.162C>T | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996906 | c.168A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996918 | c.180G>A | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996921 | c.183G>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996940 | p.Gly68Asn | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996945 | c.207C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996969 | c.231G>C | synonymous_variant | 0.97 | capreomycin | |
| Rv2681 | 2996974 | p.Glu79Gly | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2996987 | c.249A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2996990 | c.252G>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997013 | p.Gly92Ala | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997021 | c.283T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997028 | p.Val97Ala | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997033 | p.Ala99Arg | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997038 | c.300G>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997053 | c.315C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997054 | p.Ser106Gly | missense_variant | 1.0 | capreomycin | Uncertain significance |
| Rv2681 | 2997060 | p.Asn108Asp | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997065 | c.327G>A | synonymous_variant | 0.97 | capreomycin | |
| Rv2681 | 2997092 | c.354T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997101 | c.363T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997104 | c.366C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997116 | c.378T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997122 | c.384A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
| Rv2681 | 2997125 | c.387G>A | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997128 | c.390A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997134 | c.396A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997149 | c.411T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997155 | c.417G>A | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997158 | c.420C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997173 | c.435T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997176 | c.438A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2752c | 3064566 | c.1626G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064584 | c.1608G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064596 | c.1596G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064599 | c.1593A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064602 | c.1590T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064628 | p.Asn522Asp | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3064635 | c.1557G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064640 | c.1552T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064642 | p.Ser517Gln | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064644 | c.1548A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064653 | c.1539A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064659 | c.1533G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064664 | p.Lys510Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064677 | c.1515A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064896 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064914 | c.1278T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3064932 | c.1260T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064941 | c.1249_1251delCAAinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3064947 | c.1245A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064950 | c.1242C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3064955 | p.Thr413Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064958 | p.Ser412Arg | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3064959 | c.1233C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064962 | c.1230C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3064980 | c.1212C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3064998 | c.1194A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065004 | c.1188G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065324 | p.Ala290Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065334 | c.858C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065337 | c.855T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065346 | p.Ala282Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065352 | c.840A>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065355 | c.837A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065901 | c.291A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065908 | p.Lys95Arg | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065916 | c.276T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065947 | p.Gly82Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065955 | c.235_237delTTGinsCA | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065963 | c.229C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3065979 | c.213T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065988 | c.204A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3065993 | p.Val67Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| Rv2752c | 3065994 | c.198T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066002 | p.Met64Leu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066015 | c.177G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066018 | c.174T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066024 | c.168T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066039 | p.Gly51Thr | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066042 | c.150T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066050 | p.Leu48Met | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066054 | c.138T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066066 | c.126T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066071 | c.121T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066074 | c.118C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066075 | c.117A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066087 | c.105A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| Rv2752c | 3066432 | c.-241T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066459 | c.-268T>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066465 | c.-274G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066468 | c.-277C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066471 | c.-280A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066477 | c.-286C>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066480 | c.-291_-289delGCCinsTT | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066486 | c.-295G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066513 | c.-322C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066522 | c.-331C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066531 | c.-340C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066601 | c.-410C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066618 | c.-427A>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066663 | c.-472G>A | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066675 | c.-485_-484delCGinsTC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066681 | c.-490G>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066687 | c.-496G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066696 | c.-505T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066707 | c.-516A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066715 | c.-524A>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066744 | c.-553C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066747 | c.-558_-556delCAAinsATC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066756 | c.-567_-565delCGGinsACC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066771 | c.-580C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066774 | c.-583T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066780 | c.-589C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066807 | c.-616T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066819 | c.-630_-628delTGTinsGCC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066822 | c.-631T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066839 | c.-648A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066846 | c.-655G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066855 | c.-664T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066867 | c.-676T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066876 | c.-685T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066879 | c.-688T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066891 | c.-700G>T | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066900 | c.-709A>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066905 | c.-714T>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066906 | c.-715C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066909 | c.-719_-718delCCinsTG | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066912 | c.-721G>C | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066925 | c.-735_-734delATinsCG | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066933 | c.-743_-742delGGinsAC | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| Rv2752c | 3066966 | c.-775C>G | upstream_gene_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| thyX | 3067223 | c.723G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067244 | p.Thr234Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067249 | p.Thr233Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067250 | c.694_696delGTGinsAC | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067253 | c.693G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067277 | c.669C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067282 | p.Val222Met | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067284 | p.Ala221Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067304 | c.642A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067316 | c.630A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067373 | c.573C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067406 | c.540A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067442 | c.504C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.487_489delCGCinsAG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067462 | c.484C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067463 | c.481_483delATCinsGG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067470 | p.Asn159Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067475 | c.469_471delCAAinsGG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067479 | p.Asp156Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067515 | p.Ser144Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067530 | p.Ala139Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067535 | c.411C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067541 | c.405C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067545 | p.Glu134Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067550 | c.396G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067556 | p.His130Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067559 | c.387C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067565 | p.Asp127Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067570 | p.Ala126Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067577 | p.Glu123Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067586 | c.360C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067610 | p.Lys112Asn | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067613 | c.333G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067616 | c.330C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067619 | c.327A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067631 | c.315C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067634 | c.310_312delCTCinsTG | frameshift_variant&synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067643 | c.303C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067652 | c.294T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067658 | c.288C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067673 | c.273C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067694 | c.252G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067718 | c.228C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067721 | c.225T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067739 | c.207T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067742 | c.204A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067761 | p.Arg62Lys | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067874 | c.72C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067883 | c.63C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067886 | c.60A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067889 | c.57C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067894 | c.52T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067898 | p.Asp16Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067915 | c.31C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067925 | c.21G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073874 | p.Ile200Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073887 | p.Ser195Gly | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073892 | c.580T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073893 | c.579C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074001 | c.471C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074010 | c.462C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074031 | c.441T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074056 | p.Glu139Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074061 | p.Glu137Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074076 | c.396C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074088 | c.384C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074097 | c.375C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074106 | c.366T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074120 | c.352T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074130 | c.342G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074254 | p.His73Arg | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074274 | c.198T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074285 | c.187T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074286 | c.186T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyA | 3074292 | c.180G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074305 | p.Ala56Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074307 | c.165A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074313 | c.159A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074322 | c.150C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074325 | c.147A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074334 | c.138T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074349 | c.123T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074360 | c.112T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074361 | c.111T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074397 | c.75A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074415 | c.57C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074418 | c.54A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074423 | p.Pro17Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074426 | p.Thr16Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074433 | c.39A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074442 | c.28_30delTTCinsCG | frameshift_variant&missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074463 | c.9A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| ald | 3087240 | p.Ala141Ser | missense_variant | 1.0 | cycloserine | |
| ald | 3087251 | c.432T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087254 | c.435C>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087257 | c.438T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087260 | c.441C>T | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087272 | c.453A>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087281 | c.462G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087284 | c.465C>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087290 | c.471T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087311 | c.492C>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087318 | c.499_501delGAAinsAG | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| ald | 3087321 | c.502_504delCCGinsGC | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| ald | 3087545 | c.726A>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087641 | c.822T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087659 | c.840G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087666 | p.Tyr283His | missense_variant | 1.0 | cycloserine | |
| ald | 3087671 | c.852C>T | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087698 | c.879G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087704 | c.885T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087726 | p.Ala303Ser | missense_variant | 1.0 | cycloserine | |
| ald | 3087729 | p.Ser304Ala | missense_variant | 1.0 | cycloserine | |
| ald | 3087751 | p.Tyr311Phe | missense_variant | 1.0 | cycloserine | |
| ald | 3087779 | c.960T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087786 | p.Glu323Lys | missense_variant | 1.0 | cycloserine | |
| ald | 3087791 | c.972T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087800 | c.981T>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087809 | c.990G>A | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087815 | c.996G>A | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087825 | p.Asn336Asp | missense_variant | 1.0 | cycloserine | |
| ald | 3087830 | c.1011G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087833 | c.1014A>T | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087836 | c.1017A>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087840 | c.1021_1023delAAAinsCT | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| ald | 3087845 | c.1026T>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087860 | p.Glu347Asp | missense_variant | 1.0 | cycloserine | |
| fbiD | 3339246 | c.129C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiD | 3339256 | c.139T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiD | 3339607 | p.Pro164Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiD | 3339642 | c.525T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| Rv3236c | 3612694 | c.421_423delCGTinsGC | frameshift_variant&synonymous_variant | 1.0 | pyrazinamide | Uncertain significance |
| Rv3236c | 3612708 | c.409T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612712 | c.405G>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612721 | c.396G>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612730 | c.387C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| Rv3236c | 3612736 | c.381T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612757 | p.Gly120Ala | missense_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612760 | c.357C>G | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612769 | c.348T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612772 | c.345T>A | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612786 | c.331T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612787 | c.330T>G | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612796 | c.321G>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612805 | c.312T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612811 | c.306G>A | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612829 | c.288T>C | synonymous_variant | 1.0 | pyrazinamide | |
| Rv3236c | 3612838 | c.279G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| Rv3236c | 3612841 | c.276G>C | synonymous_variant | 1.0 | pyrazinamide | |
| lpqB | 3623372 | c.1539G>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R | |||||
| lpqB | 3623379 | p.Ala511Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623388 | p.Thr508Ile | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623393 | c.1518A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623411 | c.1500T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623432 | c.1479G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623442 | p.Ser490Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623444 | c.1467T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623450 | c.1461G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623468 | c.1443T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3623480 | c.1431C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623484 | p.Phe476Tyr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623492 | c.1419T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623512 | p.Gly467Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623532 | p.Gly460Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623561 | c.1350T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623570 | c.1341A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623573 | c.1338T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623576 | c.1335T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623580 | p.Asn444Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623587 | p.Ala442Pro | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623591 | c.1320G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623598 | p.Arg438Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623602 | p.Ser437Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623614 | p.Thr433Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623615 | c.1296G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623627 | c.1284T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623633 | c.1278G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623645 | c.1266G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623648 | c.1263A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623654 | p.Asp419Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623660 | c.1251A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623666 | c.1245A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623676 | p.Val412Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623682 | p.Thr410Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623684 | c.1227T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623723 | c.1188C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623731 | p.Ser394Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623736 | p.Ser392Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623739 | p.His391Arg | missense_variant | 0.96 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3623756 | c.1155G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623782 | p.Val377Ile | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3623789 | c.1122T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624002 | c.909G>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624014 | c.897T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624026 | c.885G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624032 | c.879T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624041 | p.Glu290Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624050 | c.861C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624077 | c.834G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624089 | c.822C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624094 | c.817A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624100 | c.811T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624101 | c.810C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624107 | c.804C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624125 | c.786A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624155 | c.756G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624158 | c.753G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624166 | p.Met249Leu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624167 | c.744C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624173 | c.738A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624176 | c.735G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624194 | c.717C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624200 | c.711A>G | synonymous_variant | 0.94 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624204 | p.Ser236Asn | missense_variant | 0.93 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624209 | c.702A>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624212 | c.699C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624224 | c.687T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624320 | c.591G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624323 | c.588G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624339 | p.Arg191His | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624389 | c.522C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624407 | c.504C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624416 | c.495G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624422 | c.489G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624425 | p.Glu162Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624428 | c.483A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624452 | c.459T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624455 | c.456G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624464 | c.447A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624470 | c.441T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624476 | c.435C>A | synonymous_variant | 0.97 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624482 | c.429T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624485 | p.Asp142Gly | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Not assoc w R | |||||
| lpqB | 3624518 | c.393T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624527 | p.Gln128Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624530 | c.381T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624542 | c.369G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624545 | c.366T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624551 | c.360G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624557 | c.354T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624560 | c.351G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624563 | c.348C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624572 | c.339C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624575 | c.336T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624594 | p.Val106Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624603 | p.Lys103Arg | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624605 | c.306G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624612 | p.Ser100Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624614 | c.297A>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624623 | c.288C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624629 | c.282G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624646 | c.265T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624649 | c.262T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624680 | c.231T>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624686 | c.223_225delGAAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624701 | c.210T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624707 | c.204G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624722 | c.189C>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624728 | c.183C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624749 | c.162G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624755 | c.154_156delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| lpqB | 3624770 | c.141T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624776 | c.135T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624783 | p.Ser43Thr | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624788 | c.123A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3624797 | c.114T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624807 | p.Val35Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624812 | c.99T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624815 | c.96A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3624824 | c.87A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625060 | c.-150G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Not assoc w R | |||||
| lpqB | 3625066 | c.-156G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625080 | c.-170C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625090 | c.-180C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625095 | p.Glu507Gln | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625102 | c.-192A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625117 | c.-207T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625134 | c.-224T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625135 | c.1479A>G | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625141 | c.-231T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625149 | p.Val489Ile | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625161 | c.-251T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625162 | c.1452T>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625183 | c.-273G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625186 | c.-276T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625189 | c.1425A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625195 | c.-285A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625201 | c.-291T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625222 | c.1392T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625240 | c.-330T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625243 | c.-333T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625255 | c.-345T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625258 | c.-348G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625267 | c.1347T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625270 | c.-360G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625279 | c.-369C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625285 | c.-375G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625291 | c.-381A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625294 | c.-384C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625298 | p.Ala439Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625301 | p.Ala438Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625327 | c.-417A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625345 | c.-435T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625351 | c.1263T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625357 | c.-447T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625366 | c.-456C>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625372 | c.-462A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625375 | c.-465A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625381 | c.-471T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625387 | c.-477T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625426 | c.-516G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625431 | c.-521T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625438 | c.-528T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625465 | c.-555T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625471 | c.-561C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625478 | p.Asn379Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625480 | c.1132_1134delAACinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | Uncertain significance |
| rifampicin | Uncertain significance | |||||
| lpqB | 3625483 | c.-573C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625486 | c.-576G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625489 | c.-579A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625497 | c.1117T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625501 | c.-591C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625510 | c.-600T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625513 | c.-603G>C | upstream_gene_variant | 0.97 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625528 | c.-618G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625537 | c.-627T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625543 | c.-633G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625569 | c.1045T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625592 | p.Ser341Asn | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 0.98 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625675 | c.-765G>C | upstream_gene_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.98 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625717 | c.-807C>T | upstream_gene_variant | 0.96 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625720 | c.894G>C | synonymous_variant | 0.97 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 0.96 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.98 | bedaquiline | |
| rifampicin | Uncertain significance | |||||
| mtrB | 3625762 | c.852A>G | synonymous_variant | 0.98 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 0.98 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 0.98 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625867 | c.747A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| lpqB | 3625891 | c.-981G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625912 | c.702G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625915 | c.699G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625920 | c.694C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625927 | c.687T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625930 | c.684C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625942 | c.672C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625945 | c.669A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625951 | c.663A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625955 | p.Leu220Ala | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625967 | p.Ala216Ile | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625978 | c.636T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625988 | p.Thr209Gln | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3625999 | c.615A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626009 | p.Ala202Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626017 | c.597T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626029 | c.585A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626035 | c.579G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626048 | p.Arg189Gln | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626054 | p.Leu187Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626062 | c.552T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626065 | c.549G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626070 | p.Ile182Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626077 | c.537C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626086 | c.528C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626092 | c.522T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626095 | p.Glu173Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626101 | p.Gln171His | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626125 | c.489C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626131 | c.483G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626308 | c.306T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626317 | c.297A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626320 | c.294C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626332 | c.282T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626349 | p.Ser89Gly | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626353 | c.261C>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626362 | c.252A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626377 | p.Asp79Glu | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626383 | c.231G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626386 | c.228G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626390 | p.Arg75Lys | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626400 | p.Ile72Val | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626404 | c.210C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626407 | c.207C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626410 | c.204T>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626413 | c.201T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626437 | c.177T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626443 | c.171T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626449 | c.165G>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626455 | c.159C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626458 | c.156C>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626463 | c.151C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626470 | c.144A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626491 | c.123G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626500 | c.114G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626723 | c.627C>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626729 | c.-116G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626732 | c.-119A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626735 | c.-122C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626852 | c.-239G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626857 | c.-244T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626879 | c.-266G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626882 | c.468G>C | synonymous_variant | 1.0 | bedaquiline | Not assoc w R - Interim |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3626888 | c.460_462delTTGinsCA | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626891 | c.-278G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3626915 | c.-302C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626924 | c.-311G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3626939 | p.Glu137Asp | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3626996 | c.-383G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627011 | c.-398T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627059 | c.-446G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627101 | c.-488C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627170 | c.-557C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627173 | c.-560G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrA | 3627188 | c.160_162delTTAinsCG | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627212 | c.-599C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627218 | c.-605G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627227 | c.123T>C | synonymous_variant | 1.0 | bedaquiline | |
| rifampicin | Not assoc w R - Interim | |||||
| mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627236 | c.-623T>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627287 | c.-674C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627296 | c.-683T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627301 | c.-688T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627343 | p.Thr3Ser | missense_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrB | 3627377 | c.-764G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627857 | c.-508G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| mtrA | 3627863 | c.-514G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| rifampicin | ||||||
| fbiB | 3640839 | c.-696C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640850 | p.Glu103Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640854 | c.-681C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640857 | c.-678G>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640866 | c.-669T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640901 | p.Gln120Arg | missense_variant | 1.0 | clofazimine | Uncertain significance |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fbiB | 3640911 | c.-624C>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640914 | c.-621C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640917 | c.-618G>A | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640920 | c.-615A>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640930 | p.Glu130Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640935 | c.-600C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640938 | c.-597A>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640944 | c.-591T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640962 | c.-573C>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640965 | c.-570C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640966 | c.-569T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3640974 | c.432T>G | synonymous_variant | 0.92 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiA | 3640979 | p.Thr146Ser | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640983 | c.-552C>T | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640989 | c.-546T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640995 | c.-540A>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3640998 | c.-537C>A | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641001 | c.-534T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641004 | c.-531A>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641073 | c.-462T>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641097 | c.-438T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641100 | c.-435T>A | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641103 | c.-432T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641112 | c.-423T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3641118 | p.Lys192Asn | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3641119 | p.Ser193Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641127 | c.-408T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3641128 | p.Ala196Thr | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3641164 | p.Ile208Val | missense_variant | 1.0 | clofazimine | Uncertain significance |
| pretomanid | ||||||
| delamanid | Uncertain significance | |||||
| fbiA | 3641170 | p.Met210Leu | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641184 | c.-351T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641187 | c.-348T>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3641200 | p.Ile220Val | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641220 | c.-315C>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641226 | c.-309G>C | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiA | 3641286 | c.744C>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
| pretomanid | ||||||
| delamanid | Not assoc w R - Interim | |||||
| fbiA | 3641288 | p.Glu249Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641328 | c.-207T>G | upstream_gene_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641606 | c.72T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641627 | c.93C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641642 | c.108G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641645 | c.111A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641648 | c.114G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641654 | c.120A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641663 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641678 | c.144T>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641846 | c.312G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641880 | p.Ser116Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641885 | c.351G>A | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641888 | c.354A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641909 | c.375T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641918 | c.384T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641924 | c.390A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641928 | c.394T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641933 | c.399C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641945 | c.411C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641961 | p.Thr143Asp | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641987 | c.453C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641993 | c.459A>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3641999 | c.465C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642630 | p.Thr366Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642634 | p.Asp367Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642656 | c.1122G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642662 | c.1128C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642668 | c.1134A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642677 | c.1143A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642680 | c.1146A>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642683 | c.1149C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642684 | c.1150T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642694 | p.Ala387Gly | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642701 | c.1167C>G | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642704 | c.1170G>T | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642719 | c.1185T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642743 | c.1209T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642749 | c.1215T>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642763 | p.Asp410Ala | missense_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| fbiB | 3642770 | c.1236G>C | synonymous_variant | 1.0 | clofazimine | |
| pretomanid | ||||||
| delamanid | ||||||
| alr | 3840221 | c.1200G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840230 | c.1191T>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840233 | c.1188A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840236 | c.1185A>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840239 | c.1182G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840244 | p.Ser393Gly | missense_variant | 1.0 | cycloserine | |
| alr | 3840248 | c.1173C>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840274 | p.Val383Leu | missense_variant | 1.0 | cycloserine | |
| alr | 3840275 | c.1146T>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840278 | c.1143T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840287 | c.1134C>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840293 | c.1128T>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840296 | c.1125G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840305 | c.1116T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840309 | p.Arg371Ala | missense_variant | 1.0 | cycloserine | |
| alr | 3840312 | p.Ile370Thr | missense_variant | 1.0 | cycloserine | |
| alr | 3840328 | c.1093T>C | synonymous_variant | 0.95 | cycloserine | |
| alr | 3840329 | c.1092T>C | synonymous_variant | 0.95 | cycloserine | |
| alr | 3840356 | c.1063_1065delCTTinsGC | frameshift_variant&missense_variant | 0.96 | cycloserine | |
| alr | 3840360 | p.Pro354Gln | missense_variant | 0.96 | cycloserine | |
| alr | 3840380 | c.1039_1041delATGinsCC | frameshift_variant&missense_variant | 0.96 | cycloserine | |
| alr | 3840407 | c.1014G>C | synonymous_variant | 0.95 | cycloserine | |
| alr | 3840416 | c.1003_1005delTGCinsCG | frameshift_variant&missense_variant | 0.94 | cycloserine | |
| alr | 3840419 | c.1002A>G | synonymous_variant | 0.94 | cycloserine | |
| alr | 3840422 | c.997_999delAGAinsGG | frameshift_variant&synonymous_variant | 0.94 | cycloserine | |
| alr | 3840460 | p.Ser321Thr | missense_variant | 1.0 | cycloserine | |
| alr | 3840476 | c.945A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840482 | c.939T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840512 | c.909C>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840515 | p.Pro302Asp | missense_variant | 1.0 | cycloserine | |
| alr | 3840518 | c.903G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840523 | p.Ile300Val | missense_variant | 1.0 | cycloserine | |
| alr | 3840527 | c.894A>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840533 | c.888G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840539 | c.882G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840551 | c.870G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840554 | c.865_867delGCGinsAC | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| alr | 3840557 | c.864T>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840562 | p.Ile287Val | missense_variant | 1.0 | cycloserine | |
| alr | 3840575 | c.846G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840578 | c.843T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840584 | c.837T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840593 | c.828C>G | synonymous_variant | 0.95 | cycloserine | |
| alr | 3840941 | c.480C>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840944 | c.477T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840959 | c.462G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840971 | c.450G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840974 | c.447C>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3840994 | p.His143Asp | missense_variant | 1.0 | cycloserine | |
| alr | 3840997 | c.424T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841001 | c.420A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841010 | c.411A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841013 | c.408C>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841018 | p.Leu135Val | missense_variant | 1.0 | cycloserine | |
| alr | 3841028 | c.393G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841033 | p.Val130Ile | missense_variant | 1.0 | cycloserine | |
| alr | 3841036 | p.Gln129Glu | missense_variant | 1.0 | cycloserine | |
| alr | 3841055 | c.366C>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841064 | c.357C>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841094 | c.325_327delGTGinsAC | frameshift_variant&missense_variant | 1.0 | cycloserine | |
| alr | 3841100 | c.321A>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841106 | c.315T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841109 | c.312C>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841112 | c.309T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841115 | c.306T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841127 | c.294A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841130 | c.291G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841133 | c.288G>A | synonymous_variant | 1.0 | cycloserine | |
| rpoA | 3877503 | c.1005G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877567 | p.Ser314Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877569 | c.939G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877587 | c.921A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877677 | p.Ala277Ser | missense_variant | 0.96 | rifampicin | |
| rpoA | 3877685 | c.823C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877875 | c.633T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877889 | p.Ala207Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877896 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877909 | p.Asn200Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877950 | c.558C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878046 | c.462T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878094 | c.414C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878130 | c.378C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878160 | c.348C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878163 | c.345C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878199 | c.309T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878256 | c.252G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878292 | c.216T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878361 | c.147G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878409 | c.99C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878430 | c.78G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878454 | c.54A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878480 | p.Ser10Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878484 | c.24C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878490 | c.18C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878714 | c.-207C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878722 | c.-215C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878725 | c.-220_-218delCTAinsTG | upstream_gene_variant | 0.92 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878749 | c.-242G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878761 | c.-254G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878769 | c.-262C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878779 | c.-272C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878785 | c.-278T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878791 | c.-284C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878806 | c.-299C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878821 | c.-314G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878830 | c.-323G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878833 | c.-326C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878836 | c.-331_-329delAAGinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878869 | c.-362G>A | upstream_gene_variant | 0.97 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878935 | c.-428C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878938 | c.-431T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878953 | c.-446C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878976 | c.-469A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878995 | c.-488A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879002 | c.-497_-496delGA | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879007 | c.-501_-500insTC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879037 | c.-530G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879130 | c.-623A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879202 | c.-695T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879229 | c.-722A>G | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986627 | c.-217C>T | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986636 | c.-208C>T | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986637 | c.-207C>T | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986654 | c.-190C>A | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 1.0 | delamanid | |
| pretomanid | ||||||
| clpC1 | 4038212 | c.2493T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038239 | c.2466T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038248 | c.2457C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038271 | p.Pro812Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038272 | c.2433T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038278 | c.2427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038302 | c.2403C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038308 | c.2397G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038314 | c.2391T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038347 | c.2358G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038356 | c.2349T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038359 | c.2346A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038395 | c.2310C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038433 | c.2272C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038460 | p.Leu749Met | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038494 | c.2211G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038499 | p.Ser736Gly | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038559 | p.Ile716Val | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038560 | p.Asp715Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038587 | c.2118C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038755 | c.1950G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038815 | c.1890G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039031 | c.1674T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039037 | c.1668T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039046 | c.1659C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039103 | c.1602T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039268 | c.1437C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039277 | c.1428C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039295 | c.1410A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039304 | c.1401G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039319 | c.1386T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039331 | c.1374C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039337 | p.Thr456Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039346 | c.1359G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039391 | c.1314T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039406 | c.1299G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039463 | c.1242C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039466 | c.1239T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039469 | c.1236T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039484 | c.1221T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039517 | c.1188C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039556 | c.1149G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039574 | c.1129_1131delGCGinsTC | frameshift_variant&missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039610 | c.1095G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039616 | c.1089G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039621 | c.1084C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039661 | c.1044T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039679 | c.1026C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039682 | c.1023C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039760 | c.945T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039769 | c.936C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039790 | c.915C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039823 | c.882T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039904 | c.801A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039913 | c.792C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039916 | c.789T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039925 | c.780C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039934 | c.771G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039979 | c.726C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039991 | c.714G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4040090 | c.615T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040153 | c.552A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040201 | c.504C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040207 | c.498T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040210 | c.495G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040213 | c.490_492delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040219 | c.486C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040225 | c.480A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040228 | c.477G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040234 | c.471C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040237 | c.468C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040277 | c.427_428delTCinsAG | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040279 | c.426C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040336 | c.369G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040423 | c.282A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040426 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040444 | c.261C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040477 | c.228G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040480 | c.225T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040486 | c.219G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040528 | c.177G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040567 | c.138C>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040570 | c.135C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040585 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040591 | c.114C>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040596 | c.109C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040600 | c.105A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040654 | c.51G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4041008 | c.-304C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| clpC1 | 4041011 | c.-307C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044093 | c.189A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044120 | c.162A>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044123 | c.159T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044126 | c.156T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044138 | c.144T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044150 | c.132A>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044159 | c.123C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044162 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044165 | c.117G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044188 | c.94T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044195 | c.87T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044237 | c.45G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044240 | c.42G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044264 | c.18G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044270 | c.12G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044656 | c.-375G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044662 | c.-381C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044668 | c.-387G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044671 | c.-390G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044677 | c.-396T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044682 | c.-401C>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044686 | c.-405C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044692 | c.-411G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044713 | c.-432G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044725 | c.-444C>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044737 | c.-456T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044752 | c.-471T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044755 | c.-474G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044779 | c.-500_-498delCTAinsTGC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044785 | c.-504C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044788 | c.-507G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044809 | c.-528C>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044818 | c.-539_-537delCCGinsGC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044822 | c.-541G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044844 | c.-563T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044848 | c.-567T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044854 | c.-573A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044895 | c.-614A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044896 | c.-615T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044899 | c.-618A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044904 | c.-623A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044908 | c.-628_-627delCTinsTG | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044914 | c.-633A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044917 | c.-636G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044927 | c.-646C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044929 | c.-648G>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044935 | c.-655_-654delAAinsTG | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044953 | c.-673_-672delCGinsTC | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044959 | c.-678C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044962 | c.-681C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044965 | c.-684T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044977 | c.-696T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044989 | c.-708T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045000 | c.-719A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045028 | c.-747C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045034 | c.-753A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045055 | c.-774T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045063 | c.-782T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045064 | c.-783G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045067 | c.-786C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045073 | c.-792C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045076 | c.-795A>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045088 | c.-807T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045094 | c.-813T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045097 | c.-816T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| glpK | 4138323 | p.Arg478Gln | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4138328 | c.1428T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138334 | c.1422G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138337 | p.Ala473Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138349 | c.1407G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138364 | c.1392G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138367 | c.1389G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138376 | p.Val460Ala | missense_variant | 1.0 | ethambutol | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| streptomycin | Not assoc w R | |||||
| levofloxacin | Not assoc w R | |||||
| rifampicin | Not assoc w R | |||||
| isoniazid | Not assoc w R | |||||
| glpK | 4138379 | c.1377T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138382 | c.1374A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138385 | c.1371A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138418 | c.1338T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138424 | c.1332T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138429 | c.1327T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138442 | c.1314C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138451 | c.1305T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138464 | p.Gly431Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138466 | c.1290C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138469 | c.1287C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138472 | c.1284G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138475 | c.1281C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138478 | c.1278T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138481 | c.1275G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138495 | p.Gln421Glu | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138496 | c.1260G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138502 | c.1254T>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138511 | c.1245C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138514 | c.1242A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138517 | p.Glu413Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138523 | c.1233C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138535 | c.1221T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138547 | c.1209C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138568 | c.1188A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138610 | c.1146C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138628 | c.1128T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138634 | c.1122G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138654 | c.1102C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138670 | c.1086G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138681 | p.Met359Val | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138682 | c.1074C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138685 | c.1071C>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138696 | p.Pro354Ala | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138703 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138709 | c.1047G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138714 | p.Ala348Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138715 | c.1041G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138730 | c.1026C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138772 | c.984G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138796 | c.960A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138817 | c.939T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138829 | c.927A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138832 | c.924C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138835 | c.921C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4138841 | c.915G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138847 | c.909A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138858 | p.Asn300His | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138859 | c.897T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138862 | c.894G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138871 | c.885C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138877 | c.879A>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138880 | c.876T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138889 | c.867G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4138898 | c.858T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139339 | c.417G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139554 | p.Ala68Ser | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139570 | c.186G>A | synonymous_variant | 0.93 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139576 | c.180G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139581 | p.Asn59Asp | missense_variant | 1.0 | ethambutol | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| rifampicin | Uncertain significance | |||||
| isoniazid | Uncertain significance | |||||
| glpK | 4139588 | c.168G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139600 | c.156G>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139603 | c.153C>G | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139608 | p.Leu50Met | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139630 | c.126C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139636 | c.120C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| levofloxacin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| glpK | 4139642 | c.114G>A | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139648 | c.108T>C | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139653 | p.His35Asp | missense_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| glpK | 4139663 | c.93C>T | synonymous_variant | 1.0 | ethambutol | |
| moxifloxacin | ||||||
| streptomycin | ||||||
| levofloxacin | ||||||
| rifampicin | ||||||
| isoniazid | ||||||
| embC | 4238975 | c.-888A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4238986 | c.-877_-876delCAinsAG | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4238999 | c.-864C>G | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4239023 | c.-840C>A | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239027 | c.-836A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239032 | c.-831T>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4239033 | c.-830C>A | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239057 | c.-806A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239062 | c.-801C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239065 | c.-798G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239068 | c.-795A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239069 | c.-794_-792delTCAinsAG | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239076 | c.-787C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239079 | c.-784_-783delCAinsGG | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239083 | c.-780C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239125 | c.-738C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239129 | c.-734C>T | upstream_gene_variant | 0.92 | ethambutol | |
| embC | 4239350 | c.-513G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239383 | c.-480C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239398 | c.-465G>T | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239401 | c.-462A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239404 | c.-459G>A | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4239407 | c.-456C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239408 | c.-455G>A | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4239413 | c.-450C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239426 | c.-437_-435delCCAinsGC | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239432 | c.-431A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239437 | c.-426T>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4239451 | c.-412G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239466 | c.-397_-396delGCinsCA | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239469 | c.-394G>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4239475 | c.-388_-387delGGinsAA | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239479 | c.-384C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239482 | c.-381C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239486 | c.-377T>A | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239512 | c.-351G>C | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4239516 | c.-347T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239524 | c.-339C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4240065 | p.Ala68Glu | missense_variant | 1.0 | ethambutol | |
| embC | 4240069 | c.207T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240078 | c.216A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240090 | c.228C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240105 | c.243C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240111 | c.249C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240120 | c.258C>G | synonymous_variant | 0.94 | ethambutol | |
| embC | 4240141 | c.279A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240154 | c.293_301delAGAACACCG | disruptive_inframe_deletion | 1.0 | ethambutol | |
| embC | 4240165 | c.305_307delAGA | disruptive_inframe_deletion | 1.0 | ethambutol | |
| embC | 4240178 | c.316T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240183 | c.321A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240201 | c.339G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240204 | c.342T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240211 | p.Val117Ile | missense_variant | 1.0 | ethambutol | |
| embC | 4240216 | c.354T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240228 | c.366G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240229 | c.367_369delCTGinsAC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4240234 | c.372A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240237 | c.375G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240258 | c.396T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240264 | c.402G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240267 | c.405T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240270 | c.408T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240273 | c.411C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240277 | p.Leu139Val | missense_variant | 1.0 | ethambutol | |
| embC | 4240292 | c.430C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240297 | c.435T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240313 | p.Thr151Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240318 | c.456T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240325 | c.463T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240330 | c.468A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240348 | c.486T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240642 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240655 | p.Ala265Pro | missense_variant | 1.0 | ethambutol | |
| embC | 4240660 | c.798C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240669 | c.807G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240685 | p.Thr275Gly | missense_variant | 1.0 | ethambutol | |
| embC | 4240690 | c.828G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240693 | c.831T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240780 | c.918T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240786 | c.924C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240789 | c.927T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240807 | c.945C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240816 | c.954C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240819 | c.957A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240828 | c.966G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240831 | c.969T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240858 | c.996G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240867 | c.1005T>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240870 | c.1008T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240879 | c.1017G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240885 | c.1023T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240897 | c.1035C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240898 | c.1036C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240911 | p.Ala350Val | missense_variant | 1.0 | ethambutol | |
| embC | 4240921 | c.1059C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240936 | c.1074A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240957 | c.1095C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240960 | c.1098G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240966 | c.1104G>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240969 | c.1107C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4240979 | p.Thr373Gln | missense_variant | 1.0 | ethambutol | |
| embC | 4240990 | c.1128A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241002 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241107 | c.1245G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241203 | c.1341T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241230 | c.1368A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241411 | p.Ile517Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241449 | c.1587C>A | synonymous_variant | 0.95 | ethambutol | |
| embC | 4241455 | c.1593C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241470 | c.1608C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241479 | c.1617C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241496 | p.Ala545Gly | missense_variant | 1.0 | ethambutol | |
| embC | 4241498 | p.Val546Ile | missense_variant | 1.0 | ethambutol | |
| embC | 4241501 | p.Ser547Thr | missense_variant | 1.0 | ethambutol | |
| embC | 4241518 | c.1656A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241521 | c.1659T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241530 | c.1668C>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241536 | c.1674A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241539 | c.1677T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241542 | c.1680C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241545 | c.1683T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241548 | c.1686T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241551 | c.1689A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241567 | p.Ile569Val | missense_variant | 1.0 | ethambutol | |
| embC | 4242171 | p.Thr770Ser | missense_variant | 1.0 | ethambutol | |
| embC | 4242176 | p.Pro772Ser | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4242179 | p.Leu773Val | missense_variant | 1.0 | ethambutol | |
| embC | 4242199 | c.2337C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242202 | c.2340C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242203 | c.2341C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242208 | c.2346T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242217 | c.2355C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242220 | c.2358A>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4242245 | p.Thr795Arg | missense_variant | 1.0 | ethambutol | |
| embA | 4242647 | c.-586C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242652 | c.-581C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242653 | p.Ala931Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4242658 | c.-575A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242667 | c.-566C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242674 | p.Ser938Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4242688 | c.-545G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242689 | p.Val943Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4242694 | c.-539G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242695 | c.-538T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242710 | c.2848_2850delCAGinsGA | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embC | 4242715 | c.2853T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4242739 | c.-494C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242742 | c.-491C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242745 | c.-488A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242748 | c.-485A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4242764 | p.Val968Leu | missense_variant | 0.93 | ethambutol | |
| embA | 4242823 | c.-410G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242826 | c.-407G>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4242832 | c.-401A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4244135 | p.Glu301Asp | missense_variant | 1.0 | ethambutol | |
| embA | 4244198 | c.966C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244207 | c.975C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244567 | c.1335C>G | synonymous_variant | 0.9 | ethambutol | |
| embA | 4244585 | c.1353A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244588 | c.1356G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244611 | p.Ala460Val | missense_variant | 1.0 | ethambutol | |
| embA | 4244615 | c.1383G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244616 | p.Ala462Ser | missense_variant | 1.0 | ethambutol | |
| embA | 4244633 | c.1401C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244645 | c.1413T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244648 | c.1416G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244649 | p.Asp473Ser | missense_variant | 1.0 | ethambutol | |
| embA | 4244669 | c.1437G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244675 | c.1443A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244681 | c.1449A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244708 | c.1476C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244726 | p.Asp498Glu | missense_variant | 1.0 | ethambutol | |
| embA | 4244728 | p.Phe499Trp | missense_variant | 1.0 | ethambutol | |
| embA | 4244747 | c.1515T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244756 | c.1524G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244764 | p.Val511Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4244771 | c.1539G>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244780 | c.1548C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244783 | c.1551C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244792 | c.1560G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244802 | p.Leu524Met | missense_variant | 1.0 | ethambutol | |
| embA | 4244823 | p.Val531Met | missense_variant | 1.0 | ethambutol | |
| embA | 4244829 | c.1597_1599delTTCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4244843 | c.1611G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244855 | c.1623G>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244856 | p.Ala542Pro | missense_variant | 1.0 | ethambutol | |
| embA | 4244861 | c.1629G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244867 | c.1635C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244873 | c.1641C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244879 | c.1647C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244885 | c.1653A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244897 | c.1665T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4244900 | c.1668G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244918 | c.1686G>A | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244921 | c.1689C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244933 | c.1701A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244936 | c.1704C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244970 | p.Leu580Val | missense_variant | 1.0 | ethambutol | |
| embA | 4244978 | c.1746G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244980 | p.Val583Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4244982 | c.1750T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244987 | c.1755T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244999 | c.1767G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245005 | c.1773C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245006 | c.1774_1776delTTTinsCG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245020 | c.1788T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245023 | c.1791A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245026 | c.1794T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245029 | c.1797T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245032 | c.1800A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245041 | c.1809C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245053 | c.1821G>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245056 | c.1824C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245078 | p.Trp616Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245083 | c.1851A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245092 | c.1860C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245093 | c.1861_1863delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245101 | c.1869G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245108 | p.Tyr626Asp | missense_variant | 1.0 | ethambutol | |
| embA | 4245114 | p.Gly628Asn | missense_variant | 1.0 | ethambutol | |
| embA | 4245125 | c.1893G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245128 | c.1896G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245145 | p.Gln638Pro | missense_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245153 | p.Ile641Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245158 | c.1926C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245161 | c.1929C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245206 | c.1974A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245217 | p.Ala662Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245233 | c.2001G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245257 | c.2025A>G | synonymous_variant | 0.96 | ethambutol | |
| embA | 4245263 | c.2031A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245282 | c.2050_2052delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245285 | c.2053T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245293 | c.2061T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245296 | c.2064G>C | synonymous_variant | 0.96 | ethambutol | |
| embA | 4245299 | c.2067A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245315 | p.Val695Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4245327 | p.Ala699Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245338 | c.2106C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245340 | p.Gly703Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245345 | p.Met705Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245355 | p.Ala708Gly | missense_variant | 1.0 | ethambutol | |
| embA | 4245449 | c.2217G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245461 | c.2229C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245472 | p.Ala747Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245477 | p.Met749Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245489 | p.Val753Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245497 | c.2265C>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245509 | c.2277A>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245513 | p.Asp761Tyr | missense_variant | 1.0 | ethambutol | |
| embB | 4245518 | c.-996A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245524 | c.2292G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245527 | c.-987C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245530 | c.-984T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245531 | p.Ile767Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245535 | p.Ser768Asn | missense_variant | 1.0 | ethambutol | |
| embA | 4245569 | p.Glu779Asp | missense_variant | 1.0 | ethambutol | |
| embB | 4245575 | c.-939C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245593 | c.-921C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245594 | p.Ser788Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4245620 | c.-894T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245623 | c.-891G>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245641 | c.2409C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4245643 | p.Ala804Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245648 | p.Ile806Phe | missense_variant | 1.0 | ethambutol | |
| embA | 4245652 | p.Thr807Ser | missense_variant | 1.0 | ethambutol | |
| embA | 4245674 | c.2442A>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245677 | c.-837G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245692 | c.-822G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245693 | c.2461_2463delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4245719 | c.-795G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245725 | c.-789A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245726 | c.-788T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245737 | c.-777A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245740 | c.-774T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245743 | c.-771C>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245764 | c.-750G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245767 | c.-747G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245772 | p.Asn847Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4245782 | c.-732C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245785 | c.2553G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4245788 | c.-726C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245795 | p.Ala855Thr | missense_variant | 1.0 | ethambutol | |
| embA | 4245805 | p.Gln858Arg | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4245809 | c.-705A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4245815 | c.-699C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4245820 | p.Ser863Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4245833 | c.-681G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246184 | c.-330A>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246187 | c.-327C>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246205 | c.-309A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246211 | c.-303T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246217 | c.-297G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246220 | c.2988T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246223 | c.-291C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246235 | c.3003G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4246244 | c.-270G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246250 | c.-264G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246259 | c.-255G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246268 | c.-246G>A | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246277 | c.-237G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246280 | c.-234G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246292 | c.-222A>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246299 | p.Ser1023Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4246305 | p.Ser1025Glu | missense_variant | 1.0 | ethambutol | |
| embB | 4246316 | c.-198T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246352 | c.-162G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246359 | c.3127_3129delGCCinsTG | frameshift_variant&missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4246373 | c.-141T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246376 | c.-138G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246385 | c.-129T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embB | 4246400 | c.-114G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246413 | p.His1061Tyr | missense_variant | 1.0 | ethambutol | |
| embA | 4246419 | c.3187C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embA | 4246435 | p.Gln1068Arg | missense_variant | 1.0 | ethambutol | |
| embB | 4246439 | c.-75T>G | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4246442 | c.3210A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247437 | c.924A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247491 | c.978G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247550 | p.Ala346Asp | missense_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247567 | c.1054C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247602 | c.1089G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247629 | c.1116C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247632 | c.1119C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247645 | p.Glu378Thr | missense_variant | 1.0 | ethambutol | |
| embB | 4247650 | c.1137C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247656 | c.1143A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247657 | p.Pro382Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4247662 | c.1149C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247674 | c.1161G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247684 | c.1171T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247816 | p.Val435Ile | missense_variant | 0.93 | ethambutol | |
| embB | 4247821 | c.1308T>C | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247827 | c.1314C>G | synonymous_variant | 0.93 | ethambutol | |
| embB | 4247830 | c.1317A>G | synonymous_variant | 0.93 | ethambutol | Not assoc w R - Interim |
| embB | 4247836 | c.1323A>C | synonymous_variant | 0.94 | ethambutol | Not assoc w R - Interim |
| embB | 4247842 | c.1329T>C | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247857 | c.1344C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247881 | c.1368G>C | synonymous_variant | 0.96 | ethambutol | |
| embB | 4247887 | c.1374C>T | synonymous_variant | 0.96 | ethambutol | Not assoc w R - Interim |
| embB | 4247893 | c.1380C>T | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247897 | c.1384_1386delATGinsGC | frameshift_variant&missense_variant | 0.95 | ethambutol | |
| embB | 4247905 | c.1392G>A | synonymous_variant | 0.96 | ethambutol | |
| embB | 4247914 | c.1401G>C | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| embB | 4247916 | p.Arg468His | missense_variant | 0.96 | ethambutol | Uncertain significance |
| embB | 4247920 | c.1407T>C | synonymous_variant | 0.96 | ethambutol | |
| embB | 4247940 | p.Leu476Trp | missense_variant | 0.96 | ethambutol | |
| embB | 4247945 | c.1432T>C | synonymous_variant | 0.96 | ethambutol | |
| embB | 4247951 | c.1438_1440delTCGinsGC | frameshift_variant&missense_variant | 0.95 | ethambutol | |
| embB | 4247957 | p.Met482Leu | missense_variant | 0.95 | ethambutol | |
| embB | 4247965 | c.1452C>G | synonymous_variant | 0.95 | ethambutol | |
| embB | 4247971 | c.1458C>T | synonymous_variant | 0.95 | ethambutol | Not assoc w R - Interim |
| embB | 4247972 | p.Thr487Ser | missense_variant | 0.95 | ethambutol | |
| embB | 4247983 | c.1470G>C | synonymous_variant | 0.96 | ethambutol | |
| embB | 4248007 | c.1494C>T | synonymous_variant | 0.95 | ethambutol | |
| embB | 4248011 | p.Ser500Arg | missense_variant | 0.95 | ethambutol | |
| embB | 4248014 | p.Thr501Ala | missense_variant | 0.95 | ethambutol | Uncertain significance |
| embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4248041 | p.Ala510Asn | missense_variant | 1.0 | ethambutol | |
| embB | 4248044 | c.1531_1533delAAAinsGG | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248055 | c.1542G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248118 | c.1605T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248121 | c.1608G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248133 | c.1620C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248143 | c.1630_1632delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248157 | c.1644A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248173 | p.Val554Met | missense_variant | 1.0 | ethambutol | |
| embB | 4248178 | c.1665C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248206 | c.1693_1695delAGCinsGT | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248252 | p.Gly580Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248277 | c.1764G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248283 | c.1770C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248322 | c.1809G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248343 | c.1830G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248349 | c.1836G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248350 | c.1837T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248355 | c.1842A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248358 | c.1845C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248361 | c.1848A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248362 | p.Ser617Lys | missense_variant | 1.0 | ethambutol | |
| embB | 4248382 | c.1869C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249417 | c.2904A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249420 | c.2907G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249423 | p.Asp970Glu | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4249432 | c.2919A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249441 | c.2928A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249444 | c.2931T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249447 | c.2934G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249454 | p.Thr981Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4249459 | c.2946G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249486 | c.2973T>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249487 | c.2974T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249498 | c.2985G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249504 | c.2991G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249521 | p.Ala1003Val | missense_variant | 1.0 | ethambutol | |
| embB | 4249525 | c.3012T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249529 | p.Ile1006Val | missense_variant | 1.0 | ethambutol | |
| embB | 4249532 | p.Ala1007Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4249537 | c.3024A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249543 | c.3030G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249558 | c.3045A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249573 | c.3060T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249580 | p.Leu1023Met | missense_variant | 1.0 | ethambutol | |
| embB | 4249594 | c.3081G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249600 | c.3087A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249609 | c.3096T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249627 | c.3114G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249640 | c.3127T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4249661 | p.Ala1050Ser | missense_variant | 1.0 | ethambutol | |
| embB | 4249666 | c.3153C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249675 | c.3162C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4249686 | p.Ala1058Gly | missense_variant | 1.0 | ethambutol | |
| embB | 4249690 | c.3177C>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267235 | c.1602G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267244 | c.1593T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267247 | c.1590G>A | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267253 | c.1584T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267256 | c.1581C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267262 | c.1575T>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4267266 | p.Ala524Gly | missense_variant | 1.0 | ethambutol | |
| aftB | 4267268 | c.1569T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267283 | c.1554C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267290 | p.Ala516Gln | missense_variant | 1.0 | ethambutol | |
| aftB | 4267297 | c.1540T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267301 | c.1536C>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267305 | p.Val511Ala | missense_variant | 1.0 | ethambutol | |
| aftB | 4267309 | c.1528C>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267316 | c.1521A>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267330 | c.1507C>A | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4267337 | c.1500C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268369 | c.468C>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268386 | c.451T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268389 | c.448C>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268390 | c.447G>A | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268396 | c.441T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268404 | c.433T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268406 | p.Val144Thr | missense_variant | 1.0 | ethambutol | |
| aftB | 4268444 | c.393C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268450 | c.387A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268455 | p.Val128Leu | missense_variant | 1.0 | ethambutol | |
| aftB | 4268461 | p.Ile126Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4268462 | c.375T>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268465 | c.372A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4268470 | c.367C>T | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268480 | c.357G>C | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4268483 | c.354T>G | synonymous_variant | 1.0 | ethambutol | |
| aftB | 4269027 | c.-191C>G | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269033 | c.-197T>C | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269042 | c.-206G>C | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269051 | c.783C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4269060 | c.-224G>C | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269075 | c.757_759delATTinsGC | frameshift_variant&missense_variant | 1.0 | ethambutol | |
| ubiA | 4269099 | c.728_735delACAGCGGGinsCGGGA | missense_variant&disruptive_inframe_deletion | 1.0 | ethambutol | |
| ubiA | 4269110 | c.723dupC | frameshift_variant | 1.0 | ethambutol | |
| aftB | 4269114 | c.-278C>T | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269123 | c.-287T>G | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269143 | p.Leu231Val | missense_variant | 1.0 | ethambutol | |
| ubiA | 4269144 | c.690C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4269153 | c.-317C>G | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269171 | c.-335C>G | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269177 | c.657G>A | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| aftB | 4269549 | c.-713C>T | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269555 | c.-719C>G | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269561 | c.-725G>C | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269564 | c.-728G>C | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269573 | c.-737A>G | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269594 | c.-758A>C | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269606 | c.228T>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
| aftB | 4269612 | c.-776T>C | upstream_gene_variant | 1.0 | ethambutol | |
| aftB | 4269621 | c.-785C>G | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269627 | p.Val69Thr | missense_variant | 1.0 | ethambutol | |
| ubiA | 4269632 | p.Ala68Ser | missense_variant | 1.0 | ethambutol | |
| aftB | 4269639 | c.-803C>G | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269647 | p.Ser63Cys | missense_variant | 1.0 | ethambutol | |
| aftB | 4269660 | c.-824C>T | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269665 | p.Met57Val | missense_variant | 1.0 | ethambutol | |
| aftB | 4269666 | c.-830G>C | upstream_gene_variant | 1.0 | ethambutol | |
| ubiA | 4269688 | p.Val49Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
