TB-Profiler result

Run: SRR5341470
Summary

Run ID: SRR5341470

Sample name:

Date: 2024-04-15T00:59:05.689126

Number of reads: 350881

Percentage reads mapped: 14.74

Median coverage: 2.0

Strain: lineage4.9;lineage9

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage9 Lineage 9 None 0.06
lineage3.1.2.2 East-African-Indian RD750 0.11
lineage4 Euro-American None 0.85
lineage4.9 Euro-American (H37Rv-like) None 0.94
La1.7.1 M.bovis None 0.14
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG p.Ile335Thr Mutation from literature
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
p.Asn399Asp Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1177_1179delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155107 p.Ile335Thr missense_variant 1.0 isoniazid Mutation from literature
fbiB 3642711 c.1177_1179delCTGinsGA frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 1.0 ethambutol Uncertain significance Mutation from literature
embB 4247708 p.Asn399Asp missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 21 c.21A>T synonymous_variant 1.0 isoniazid
dnaA 24 c.24C>T synonymous_variant 1.0 isoniazid
dnaA 30 c.30C>G synonymous_variant 1.0 isoniazid
dnaA 33 c.33A>C synonymous_variant 1.0 isoniazid
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCT frameshift_variant&synonymous_variant 1.0 isoniazid Uncertain significance
dnaA 819 c.819C>T synonymous_variant 1.0 isoniazid
dnaA 822 c.822A>G synonymous_variant 1.0 isoniazid
dnaA 828 c.828T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 1.0 isoniazid
dnaA 837 c.837A>G synonymous_variant 1.0 isoniazid
dnaA 840 c.840G>A synonymous_variant 1.0 isoniazid
dnaA 846 c.846T>C synonymous_variant 1.0 isoniazid
dnaA 849 c.849A>G synonymous_variant 1.0 isoniazid
dnaA 852 c.852G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 1.0 isoniazid
dnaA 885 c.885T>C synonymous_variant 1.0 isoniazid
dnaA 891 c.891C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 897 c.897A>G synonymous_variant 1.0 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 1.0 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 1.0 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 1.0 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 1.0 isoniazid
dnaA 1078 c.1078_1080delCTCinsTG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 1092 c.1092T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1095 c.1095C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 1.0 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 1.0 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 1.0 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 1.0 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 1.0 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 1.0 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 1.0 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 1.0 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 1.0 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1299 c.1299G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1302 c.1302C>G synonymous_variant 1.0 isoniazid
dnaA 1428 c.1428C>G synonymous_variant 1.0 isoniazid
dnaA 1434 c.1434C>A synonymous_variant 1.0 isoniazid
dnaA 1437 c.1437G>A synonymous_variant 1.0 isoniazid
dnaA 1441 c.1441C>T synonymous_variant 1.0 isoniazid
dnaA 1446 c.1446C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1461 c.1461C>A synonymous_variant 1.0 isoniazid
dnaA 1467 c.1467G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1473 c.1473T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 1497 c.1497T>G synonymous_variant 1.0 isoniazid
dnaA 1500 c.1500C>G synonymous_variant 1.0 isoniazid
dnaA 1506 c.1506T>A synonymous_variant 1.0 isoniazid
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6148 c.909C>A synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6316 c.-986G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6358 c.1119C>G synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6361 c.-941G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6362 c.1123_1125delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6382 c.-920A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6674 c.1435_1437delCTTinsTG frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 1.0 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6949 c.-353A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7066 c.-236G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7069 c.-233C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7075 c.-227T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7174 c.-128C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7322 c.21G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7325 c.24delTinsAGGC conservative_inframe_insertion&synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7334 c.33G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7335 p.Leu12Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7349 c.48A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7361 c.60C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 c.61_63delGAGinsCA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7643 c.342C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7646 c.345C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 1.0 levofloxacin
moxifloxacin
gyrA 7820 c.519G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8694 c.1393C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8840 c.1539C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8888 c.1587C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9128 c.1827C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9167 c.1866C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9315 c.2014C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9326 c.2025G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490917 c.135C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490983 c.201G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490988 p.Leu69Gln missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491136 c.354C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491175 c.393G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491178 c.396G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
mshA 574616 c.-732G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574640 c.-708G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574646 c.-702G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575072 c.-276G>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575081 c.-267A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575087 c.-261C>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575109 c.-239G>T upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575114 c.-234G>A upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575117 c.-231T>C upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575118 c.-230A>G upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575123 c.-225A>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575124 c.-224_-222delGGGinsCT upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575144 c.-204T>G upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575153 c.-195C>A upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575161 c.-187_-186delTTinsCC upstream_gene_variant 1.0 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 1.0 ethionamide
isoniazid
mshA 575779 p.Glu144Asp missense_variant 1.0 ethionamide
isoniazid
mshA 575780 c.433_435delCCGinsGC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575821 c.474G>C synonymous_variant 0.93 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575851 c.504C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620238 c.348G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620685 c.795G>A synonymous_variant 1.0 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620781 c.891C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 657210 c.261C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
Rv0565c 657213 c.258C>T synonymous_variant 1.0 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 1.0 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 1.0 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 1.0 ethionamide Uncertain significance
Rv0565c 657252 c.219G>C synonymous_variant 1.0 ethionamide
Rv0565c 657255 c.216G>A synonymous_variant 1.0 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 1.0 ethionamide
Rv0565c 657294 c.177C>A synonymous_variant 1.0 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657659 c.-189G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657668 c.-198C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657695 c.-225C>G upstream_gene_variant 1.0 ethionamide
hadA 731698 c.-232T>G upstream_gene_variant 0.9 isoniazid
hadA 731708 c.-222G>A upstream_gene_variant 0.93 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.94 isoniazid
hadA 731726 c.-204C>G upstream_gene_variant 0.96 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.96 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.97 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 1.0 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 1.0 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 1.0 isoniazid
hadA 732305 c.376_378delATCinsGG frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 1.0 isoniazid
hadA 732319 c.390G>A synonymous_variant 1.0 isoniazid
hadA 732321 p.Glu131Ala missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Ile missense_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 1.0 isoniazid
hadA 732396 p.Gly156Ala missense_variant 1.0 isoniazid
hadA 732398 p.Ala157Thr missense_variant 1.0 isoniazid
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 1.0 rifampicin
nusG 734520 c.267C>A synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734545 p.Lys98Gln missense_variant 1.0 rifampicin
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734820 c.567A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734826 c.573A>G synonymous_variant 1.0 rifampicin
nusG 734829 c.576C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734841 c.588G>T synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734870 p.Ser206Asn missense_variant 1.0 rifampicin
nusG 734895 c.642A>G synonymous_variant 1.0 rifampicin
nusG 734910 c.657C>G synonymous_variant 1.0 rifampicin
nusG 734913 c.660C>G synonymous_variant 1.0 rifampicin
nusG 734931 c.678A>T synonymous_variant 1.0 rifampicin
nusG 734940 c.687G>A synonymous_variant 1.0 rifampicin
nusG 734943 c.690G>C synonymous_variant 1.0 rifampicin
rpoB 760056 c.250_252delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760070 c.264T>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760109 c.303C>T synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760118 c.312T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760145 c.339C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>A synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760295 c.489C>T synonymous_variant 1.0 rifampicin
rpoB 760307 c.501T>C synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.96 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760358 c.552C>G synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 1.0 rifampicin
rpoB 760403 c.597C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>T synonymous_variant 1.0 rifampicin
rpoB 760414 p.Gly203Asp missense_variant 1.0 rifampicin
rpoB 760418 c.612G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>G synonymous_variant 1.0 rifampicin
rpoB 760520 c.714C>G synonymous_variant 1.0 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760526 c.720G>A synonymous_variant 1.0 rifampicin
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 1.0 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760601 c.795C>T synonymous_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760622 c.816C>T synonymous_variant 1.0 rifampicin
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 1.0 rifampicin
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760757 c.951T>C synonymous_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>G synonymous_variant 1.0 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760937 c.1131G>A synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 1.0 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 1.0 rifampicin
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 1.0 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 1.0 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 1.0 rifampicin
rpoB 761192 c.1386C>G synonymous_variant 1.0 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 1.0 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 1.0 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 1.0 rifampicin
rpoB 761432 c.1626C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761435 c.1629T>C synonymous_variant 1.0 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 1.0 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 1.0 rifampicin
rpoB 761452 p.Val549Glu missense_variant 1.0 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 1.0 rifampicin
rpoB 761465 c.1659G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761471 c.1665C>T synonymous_variant 1.0 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 1.0 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 1.0 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 1.0 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 1.0 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>A synonymous_variant 1.0 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 1.0 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 1.0 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 1.0 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>T synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 1.0 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 1.0 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762431 c.2625C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 1.0 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762563 c.-807G>A upstream_gene_variant 1.0 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 1.0 rifampicin
rpoB 762789 p.Leu995Met missense_variant 1.0 rifampicin Uncertain significance
rpoC 762794 c.-576C>G upstream_gene_variant 1.0 rifampicin
rpoB 762795 p.Asp997Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762813 p.Met1003Val missense_variant 1.0 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762902 c.-468C>T upstream_gene_variant 1.0 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 1.0 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 1.0 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763241 c.-129G>A upstream_gene_variant 1.0 rifampicin
rpoC 763250 c.-120C>T upstream_gene_variant 1.0 rifampicin
rpoC 763253 c.-117G>T upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 1.0 rifampicin
rpoC 763265 c.-105G>A upstream_gene_variant 1.0 rifampicin
rpoC 763351 c.-19T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763352 c.-18T>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoC 763402 c.33C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763414 c.45T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 1.0 rifampicin
rpoC 763444 c.75T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763636 c.267T>C synonymous_variant 1.0 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763726 c.357C>T synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763771 c.402C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763780 c.411C>G synonymous_variant 1.0 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 1.0 rifampicin
rpoC 763801 c.432C>G synonymous_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 1.0 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763936 c.567C>G synonymous_variant 1.0 rifampicin
rpoC 763939 c.570G>A synonymous_variant 1.0 rifampicin
rpoC 763951 c.582G>A synonymous_variant 1.0 rifampicin
rpoC 763963 c.594C>G synonymous_variant 1.0 rifampicin
rpoC 763967 p.Gly200Ser missense_variant 1.0 rifampicin
rpoC 763972 c.603C>T synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655T>C synonymous_variant 1.0 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>G synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764159 c.790C>T synonymous_variant 1.0 rifampicin
rpoC 764167 c.798G>A synonymous_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 1.0 rifampicin
rpoC 764215 c.846A>C synonymous_variant 0.97 rifampicin
rpoC 764218 c.849C>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>A synonymous_variant 1.0 rifampicin
rpoC 764246 c.877_879delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>G synonymous_variant 1.0 rifampicin
rpoC 764365 c.996C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 1.0 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 1.0 rifampicin
rpoC 764605 c.1236G>A synonymous_variant 1.0 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 1.0 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 1.0 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 1.0 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 1.0 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765278 c.1909C>T synonymous_variant 1.0 rifampicin
rpoC 765283 c.1914C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765292 c.1923G>T synonymous_variant 1.0 rifampicin
rpoC 765300 p.Val644Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 1.0 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 1.0 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 1.0 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765391 c.2022C>T synonymous_variant 1.0 rifampicin
rpoC 765406 c.2037G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.97 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 1.0 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 1.0 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 1.0 rifampicin
rpoC 765625 c.2256C>T synonymous_variant 1.0 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765670 c.2301C>T synonymous_variant 1.0 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 1.0 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 1.0 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 1.0 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 1.0 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 1.0 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766061 p.Val898Ile missense_variant 1.0 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 1.0 rifampicin
rpoC 766093 c.2724C>A synonymous_variant 1.0 rifampicin
rpoC 766095 p.Thr909Ser missense_variant 1.0 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 1.0 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 1.0 rifampicin
rpoC 766309 c.2940G>A synonymous_variant 1.0 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 1.0 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 1.0 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 1.0 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 1.0 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 1.0 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 1.0 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 1.0 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.96 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.96 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.97 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.97 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 1.0 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 1.0 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 1.0 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.95 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.92 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 0.91 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.94 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.95 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.96 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 1.0 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 1.0 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 1.0 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 1.0 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>G synonymous_variant 1.0 rifampicin
rpoC 766996 c.3627C>G synonymous_variant 1.0 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 1.0 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 1.0 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 1.0 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 1.0 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>G synonymous_variant 1.0 rifampicin
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 1.0 rifampicin
mmpL5 775975 c.2506T>C synonymous_variant 0.91 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.91 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.92 clofazimine
bedaquiline
rpsL 781571 c.12C>T synonymous_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781616 c.57C>T synonymous_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781718 c.159C>G synonymous_variant 1.0 streptomycin
rpsL 781721 c.162C>T synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781736 c.177T>C synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>G synonymous_variant 1.0 streptomycin
rpsL 781793 c.234G>C synonymous_variant 1.0 streptomycin
rpsL 781808 c.249C>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781835 c.276T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781883 c.324G>A synonymous_variant 1.0 streptomycin
rpsL 781886 c.327C>T synonymous_variant 1.0 streptomycin
rpsL 781892 c.333A>G synonymous_variant 1.0 streptomycin
rpsL 781898 c.339A>T synonymous_variant 1.0 streptomycin
rpsL 781916 c.357T>C synonymous_variant 1.0 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 1.0 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 1.0 streptomycin
rplC 800516 c.-293G>T upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 1.0 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 1.0 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 801222 c.414T>C synonymous_variant 1.0 linezolid
rplC 801228 c.420T>C synonymous_variant 1.0 linezolid
rplC 801231 c.423C>T synonymous_variant 1.0 linezolid
rplC 801246 c.438C>T synonymous_variant 1.0 linezolid
rplC 801255 c.447C>A synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801270 c.462T>C synonymous_variant 1.0 linezolid
rplC 801273 c.465C>G synonymous_variant 1.0 linezolid
rplC 801279 c.471G>C synonymous_variant 1.0 linezolid
rplC 801285 c.477G>A synonymous_variant 1.0 linezolid
rplC 801309 c.501C>G synonymous_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303538 p.Arg203Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303596 c.666G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303629 c.699C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304502 c.1572G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304532 c.1602G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304541 c.1611C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304631 c.1701C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304925 c.1995G>A synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304928 c.1998T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
sigE 1364703 c.291G>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 1.0 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364745 c.333C>T synonymous_variant 1.0 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364751 c.339C>G synonymous_variant 1.0 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.93 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
embR 1416310 c.1038G>C synonymous_variant 1.0 ethambutol
embR 1416313 c.1035A>G synonymous_variant 1.0 ethambutol
embR 1416316 c.1032C>G synonymous_variant 1.0 ethambutol
embR 1416330 p.Val340Ile missense_variant 1.0 ethambutol
embR 1416332 p.Tyr339Phe missense_variant 1.0 ethambutol
embR 1416335 p.Asn338Ser missense_variant 1.0 ethambutol
embR 1416343 c.1005G>C synonymous_variant 1.0 ethambutol
embR 1416364 c.984C>T synonymous_variant 1.0 ethambutol
atpE 1460807 c.-238C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460816 c.-229T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460828 c.-217C>T upstream_gene_variant 1.0 bedaquiline
atpE 1460831 c.-214T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460840 c.-205A>G upstream_gene_variant 1.0 bedaquiline
atpE 1460855 c.-190T>C upstream_gene_variant 1.0 bedaquiline
atpE 1460858 c.-187C>G upstream_gene_variant 1.0 bedaquiline
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472463 n.618G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.98 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.97 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473417 n.-241C>T upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473420 n.-238A>G upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473421 n.-237G>A upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473437 n.-221T>C upstream_gene_variant 1.0 capreomycin
linezolid
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473676 n.19G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473918 n.261C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473943 n.286G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473981 n.324delGinsAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473994 n.337C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Not assoc w R
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474011 n.354G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474018 n.361G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474030 n.373G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474089 n.432C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474100 n.443C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474110 n.453A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474409 n.756_774delACCCACACGCGCATACGCG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474433 n.776G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474435 n.779_783delTGAAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474995 n.1338T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475007 n.1350C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475018 n.1361G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475401 n.1745delC non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475404 n.1747A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475405 n.1748A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475453 n.1796T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475480 n.1823A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475487 n.1830C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475616 n.1959A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673505 c.-697A>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673517 c.-685G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673524 c.-678C>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673565 c.-637G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674507 c.306G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674537 c.336C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674588 c.387G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 1.0 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 0.94 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 0.93 ethionamide
isoniazid
inhA 1674687 c.486G>A synonymous_variant 0.9 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674820 c.619_621delCTCinsTG frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674888 c.687C>T synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 0.97 ethionamide
isoniazid
inhA 1674939 c.738G>A synonymous_variant 0.95 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674942 c.741T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 1.0 ethionamide
isoniazid
inhA 1675006 c.805_807delCTCinsTG frameshift_variant&missense_variant 0.91 ethionamide
isoniazid
rpsA 1833532 c.-10A>C upstream_gene_variant 1.0 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833895 c.354G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833964 c.423C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833970 c.429G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834603 c.1062G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 1.0 pyrazinamide
tsnR 1853369 c.-237C>T upstream_gene_variant 0.96 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.96 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.96 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.95 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.95 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 0.95 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.95 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 1.0 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 1.0 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 1.0 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 1.0 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 1.0 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 1.0 linezolid
tsnR 1853493 c.-113G>A upstream_gene_variant 1.0 linezolid
ndh 2101795 c.1248G>C synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101813 c.1230G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101825 c.1218G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101837 p.Ala402Val missense_variant 1.0 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2101879 c.1164C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101890 p.Val385Leu missense_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102632 c.411C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102638 c.405A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102674 c.369G>A synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102677 c.366C>G synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 1.0 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 1.0 ethionamide
delamanid
isoniazid
katG 2155026 c.1086C>G synonymous_variant 1.0 isoniazid
katG 2155047 c.1065C>G synonymous_variant 1.0 isoniazid
katG 2155054 p.Tyr353Phe missense_variant 1.0 isoniazid
katG 2155056 c.1056A>G synonymous_variant 1.0 isoniazid
katG 2155062 c.1050T>C synonymous_variant 1.0 isoniazid
katG 2155068 c.1044T>G synonymous_variant 1.0 isoniazid
katG 2155071 c.1041T>G synonymous_variant 1.0 isoniazid
katG 2155080 c.1032G>C synonymous_variant 1.0 isoniazid
katG 2155083 c.1029G>C synonymous_variant 1.0 isoniazid
katG 2155086 c.1026G>A synonymous_variant 1.0 isoniazid
katG 2155119 c.993T>C synonymous_variant 1.0 isoniazid
katG 2155131 c.981A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
katG 2155134 c.978G>C synonymous_variant 1.0 isoniazid
katG 2155140 c.972C>G synonymous_variant 1.0 isoniazid
katG 2155626 c.486G>C synonymous_variant 1.0 isoniazid
katG 2155632 c.480A>G synonymous_variant 1.0 isoniazid
katG 2155637 p.Leu159Ile missense_variant 1.0 isoniazid
katG 2155641 p.Lys157Asn missense_variant 1.0 isoniazid Uncertain significance
katG 2155656 c.456G>A synonymous_variant 1.0 isoniazid
katG 2155661 p.Val151Ile missense_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517983 c.-132T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 1.0 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 1.0 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 1.0 isoniazid
kasA 2518040 c.-75G>T upstream_gene_variant 1.0 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 1.0 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 1.0 isoniazid
kasA 2518053 c.-62_-60delATTinsCG upstream_gene_variant 1.0 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 1.0 isoniazid
kasA 2518199 p.Ile29Val missense_variant 1.0 isoniazid
kasA 2518219 c.105T>C synonymous_variant 1.0 isoniazid
kasA 2518220 c.106C>T synonymous_variant 1.0 isoniazid
kasA 2518245 p.His44Arg missense_variant 1.0 isoniazid
kasA 2518248 p.Ala45Val missense_variant 1.0 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 1.0 isoniazid
kasA 2518273 c.159G>A synonymous_variant 1.0 isoniazid
kasA 2518768 c.654C>G synonymous_variant 1.0 isoniazid
kasA 2518783 c.669T>C synonymous_variant 1.0 isoniazid
kasA 2518789 c.675G>C synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>A synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>C synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518840 c.726C>G synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>G synonymous_variant 1.0 isoniazid
kasA 2518846 c.732G>C synonymous_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518879 c.765A>G synonymous_variant 1.0 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 1.0 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 1.0 isoniazid
folC 2747086 c.513A>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 1.0 para-aminosalicylic_acid
folC 2747098 c.501C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 1.0 para-aminosalicylic_acid
folC 2747122 c.477G>A synonymous_variant 1.0 para-aminosalicylic_acid
Rv2477c 2783314 c.729C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783320 c.723C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783347 c.696C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783427 p.Pro206Ala missense_variant 0.96 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783431 c.612C>T synonymous_variant 0.96 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783437 c.606G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783458 c.585G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.96 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783578 c.465G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783602 c.441G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783623 c.420G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783632 c.411C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783764 c.277_279delATGinsCA frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783788 c.255T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783794 c.249G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783827 c.216C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783881 c.160_162delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783884 c.159T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783968 c.75G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
pepQ 2859723 c.696T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline
pepQ 2859732 c.687C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859735 c.684G>C synonymous_variant 1.0 clofazimine
bedaquiline
Rv2680 2996058 c.-47C>A upstream_gene_variant 1.0 capreomycin
Rv2680 2996060 c.-45T>C upstream_gene_variant 1.0 capreomycin
Rv2680 2996061 c.-44C>G upstream_gene_variant 1.0 capreomycin
Rv2680 2996084 c.-21A>G upstream_gene_variant 0.73 capreomycin
Rv2680 2996109 p.Thr2Asn missense_variant 1.0 capreomycin
Rv2680 2996111 p.Ser3Arg missense_variant 1.0 capreomycin
Rv2752c 3064989 c.1203G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065040 c.1150_1152delCTCinsTG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065049 c.1143G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065061 c.1131C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065073 c.1119C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065097 c.1095C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1062A>G synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065154 c.1038G>A synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065190 c.1000_1002delATCinsGG frameshift_variant&missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065199 c.993T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065205 c.987T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065210 c.982T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065223 c.969T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065957 c.235T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065963 c.229C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066437 c.-246G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-268T>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066513 c.-322C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066527 c.-336C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066597 c.-406C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066617 c.-426G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066644 c.-453T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066647 c.-456G>A upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066654 c.-463G>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066676 c.-485C>T upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066696 c.-505T>C upstream_gene_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067325 c.621A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067337 c.609C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067340 c.606G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067349 c.597G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067355 c.591A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067358 c.588C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067379 c.567C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067385 c.561C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067394 c.552G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067400 c.546C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067406 c.540A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073854 c.618C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073887 p.Ser195Asp missense_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073944 c.528C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
thyA 3074056 p.Glu139Pro missense_variant 1.0 para-aminosalicylic_acid
thyA 3074070 c.402C>T synonymous_variant 1.0 para-aminosalicylic_acid
lpqB 3624356 c.555C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624371 c.540T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624377 c.534C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624389 c.522C>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624419 c.492C>T synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624422 c.489G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624425 p.Glu162Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3624428 c.483A>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624437 c.474G>A synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3625147 c.-237C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625213 c.-303C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.92 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.92 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 0.94 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625690 c.-780T>G upstream_gene_variant 0.95 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625699 c.915C>T synonymous_variant 0.95 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625717 c.-807C>T upstream_gene_variant 0.96 bedaquiline
rifampicin
mtrB 3625747 c.867G>C synonymous_variant 0.96 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625783 c.-873C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625801 c.-891G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625849 c.-939T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625870 c.-960C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626362 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626368 c.246G>A synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626377 p.Asp79Glu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626383 p.Ala77Gly missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626389 p.Arg75Lys missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626404 c.210C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626407 c.207C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626437 c.177T>C synonymous_variant 0.93 bedaquiline
rifampicin
mtrB 3626443 c.171T>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626451 c.163C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626455 c.159C>G synonymous_variant 1.0 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626750 c.-137T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626849 c.-236C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626954 c.-341C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626996 c.-383G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627023 c.-410C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627137 c.211_213delTTGinsCA frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627143 c.-530G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.162A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627197 c.-584T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627218 c.-605G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
fbiB 3642662 c.1128C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642683 c.1149C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642695 c.1161G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642707 c.1173C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642710 c.1176G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
alr 3840994 p.His143Asp missense_variant 0.93 cycloserine
alr 3840997 c.424T>C synonymous_variant 0.94 cycloserine
alr 3841001 c.420A>G synonymous_variant 0.94 cycloserine
alr 3841013 c.408C>G synonymous_variant 0.96 cycloserine
alr 3841018 p.Leu135Val missense_variant 0.96 cycloserine
alr 3841033 p.Val130Ile missense_variant 0.95 cycloserine
alr 3841036 p.Gln129Glu missense_variant 0.95 cycloserine
alr 3841037 c.384G>C synonymous_variant 0.95 cycloserine
alr 3841055 c.366C>G synonymous_variant 0.96 cycloserine
alr 3841079 c.342T>C synonymous_variant 1.0 cycloserine
alr 3841088 c.333C>T synonymous_variant 1.0 cycloserine
alr 3841100 c.321A>G synonymous_variant 1.0 cycloserine
alr 3841106 c.315T>C synonymous_variant 1.0 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 1.0 rifampicin
rpoA 3877506 p.Gly334Ala missense_variant 1.0 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 1.0 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877587 c.921A>C synonymous_variant 1.0 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 1.0 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 1.0 rifampicin
rpoA 3877638 c.870T>G synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877677 p.Ala277Ser missense_variant 1.0 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877685 c.823C>T synonymous_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877758 c.750G>C synonymous_variant 1.0 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877815 c.693C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877830 c.678C>T synonymous_variant 0.93 rifampicin
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877851 c.657C>T synonymous_variant 1.0 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877865 c.643C>T synonymous_variant 1.0 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 1.0 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 1.0 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 1.0 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877968 c.540C>G synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 1.0 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 1.0 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 1.0 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.95 rifampicin
rpoA 3878043 c.465G>C synonymous_variant 0.95 rifampicin
rpoA 3878046 c.462T>G synonymous_variant 0.95 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.95 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.94 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.93 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.93 rifampicin
rpoA 3878076 c.432C>T synonymous_variant 0.9 rifampicin
rpoA 3878145 c.363C>G synonymous_variant 1.0 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878166 c.342C>G synonymous_variant 1.0 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 1.0 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878229 c.279C>G synonymous_variant 1.0 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878295 c.213A>G synonymous_variant 1.0 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>C synonymous_variant 1.0 rifampicin
rpoA 3878334 c.174T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.95 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.96 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.96 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.96 rifampicin
rpoA 3878384 c.124C>T synonymous_variant 0.96 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.96 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoA 3878415 c.93C>T synonymous_variant 0.98 rifampicin
rpoA 3878418 c.90C>T synonymous_variant 0.97 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 1.0 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 1.0 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 1.0 rifampicin
rpoA 3878471 p.Val13Leu missense_variant 1.0 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 1.0 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 1.0 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 1.0 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 1.0 rifampicin
rpoA 3878665 c.-158A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878685 c.-178C>T upstream_gene_variant 1.0 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878713 c.-206G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878761 c.-254G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878764 c.-257A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878776 c.-269G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878779 c.-274_-272delATCinsGT upstream_gene_variant 1.0 rifampicin
rpoA 3878788 c.-281G>T upstream_gene_variant 1.0 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 1.0 rifampicin
rpoA 3878869 c.-362G>C upstream_gene_variant 1.0 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878889 c.-382A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878894 c.-387A>G upstream_gene_variant 1.0 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 1.0 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878923 c.-417_-416delGCinsCG upstream_gene_variant 1.0 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878953 c.-446C>G upstream_gene_variant 1.0 rifampicin
rpoA 3878962 c.-455G>A upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 1.0 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 1.0 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879037 c.-530G>A upstream_gene_variant 1.0 rifampicin
rpoA 3879049 c.-542A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 1.0 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879117 c.-610C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879145 c.-638G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 1.0 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 1.0 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 1.0 rifampicin
rpoA 3879178 c.-671T>G upstream_gene_variant 1.0 rifampicin
rpoA 3879187 c.-680C>T upstream_gene_variant 1.0 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 1.0 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 1.0 rifampicin
ddn 3986630 c.-214C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986636 c.-208C>G upstream_gene_variant 1.0 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 1.0 delamanid
pretomanid
clpC1 4038347 c.2358G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038425 c.2280C>A synonymous_variant 1.0 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 1.0 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 1.0 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 1.0 pyrazinamide
clpC1 4038491 c.2214C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038502 p.Ile735Val missense_variant 1.0 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038518 c.2187G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 1.0 pyrazinamide
clpC1 4038537 p.Thr723Ser missense_variant 1.0 pyrazinamide
clpC1 4038539 c.2166G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038569 c.2136C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038575 c.2130C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038620 c.2085G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038692 c.2013C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038701 c.2004G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038809 c.1896G>A synonymous_variant 1.0 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038893 c.1812C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039025 c.1680C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039119 c.1585_1586delTCinsAG synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039193 c.1512C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039243 c.1462C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039259 c.1446G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039262 c.1443C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039268 c.1437C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1384_1386delGCTinsAA frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039361 c.1344C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>A synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039526 c.1179G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039532 c.1173C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039553 c.1152C>A synonymous_variant 1.0 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039576 p.Ala377Ser missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039583 c.1122C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039748 c.957G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039955 c.750G>T synonymous_variant 1.0 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039964 c.741C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040000 c.705C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040015 c.690G>A synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040195 c.510G>T synonymous_variant 1.0 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040309 c.396C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 1.0 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040471 c.234T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040495 c.210C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040525 c.180C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 1.0 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040588 c.117T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 1.0 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040662 c.43C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040669 c.36C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040695 c.10C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040711 c.-7G>A upstream_gene_variant 1.0 pyrazinamide
panD 4044138 c.144T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044150 c.132A>G synonymous_variant 1.0 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044159 c.123C>T synonymous_variant 1.0 pyrazinamide
panD 4044162 c.120A>G synonymous_variant 1.0 pyrazinamide
panD 4044165 c.117G>A synonymous_variant 1.0 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
panD 4044180 c.102C>T synonymous_variant 1.0 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 1.0 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 1.0 pyrazinamide
panD 4044225 c.57C>T synonymous_variant 1.0 pyrazinamide
panD 4044231 p.Cys17Gln missense_variant 1.0 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 1.0 pyrazinamide
panD 4044264 c.18G>C synonymous_variant 1.0 pyrazinamide
panD 4045000 c.-719A>T upstream_gene_variant 1.0 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 1.0 pyrazinamide
panD 4045022 c.-742_-741delTCinsCG upstream_gene_variant 1.0 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 1.0 pyrazinamide
glpK 4138340 c.1416G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138352 c.1404C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138360 c.1396T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138370 c.1386C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138376 p.Val460Ala missense_variant 1.0 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138382 c.1374A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138385 c.1371A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138397 c.1359C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138427 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138550 c.1206C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138583 c.1173G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138640 c.1116C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138702 p.Gln352Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138706 c.1050C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138714 p.Ala348Ser missense_variant 0.95 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138715 c.1041G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138751 c.1005T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139120 p.Asp212Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139143 c.613T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139150 c.606G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139156 c.600C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139176 p.Val194Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139215 c.541T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139223 p.Thr178Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139230 p.Pro176Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139231 c.525A>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139588 c.168G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139597 c.159C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139609 c.145_147delATCinsGG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139630 c.126C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139633 c.123C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139652 p.His35Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139657 c.99T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
embC 4240726 c.864G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240729 c.867C>G synonymous_variant 1.0 ethambutol
embC 4240747 c.885C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240759 c.897C>G synonymous_variant 1.0 ethambutol
embC 4240765 c.903C>G synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240813 p.Phe317Leu missense_variant 1.0 ethambutol
embC 4240819 c.957A>C synonymous_variant 1.0 ethambutol
embC 4240822 c.960C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4240831 c.969T>G synonymous_variant 1.0 ethambutol
embC 4240843 c.981C>T synonymous_variant 1.0 ethambutol
embC 4241095 c.1233C>T synonymous_variant 1.0 ethambutol
embC 4241101 c.1239G>C synonymous_variant 1.0 ethambutol
embC 4241121 p.Ser420Asn missense_variant 1.0 ethambutol
embC 4241137 c.1275G>C synonymous_variant 1.0 ethambutol
embC 4241146 c.1284C>G synonymous_variant 1.0 ethambutol
embC 4241153 p.Ile431Val missense_variant 1.0 ethambutol Uncertain significance
embC 4241158 c.1296T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241161 c.1299C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embC 4241162 c.1300T>C synonymous_variant 1.0 ethambutol
embA 4245078 p.Trp616Val missense_variant 1.0 ethambutol
embA 4245083 c.1851A>C synonymous_variant 1.0 ethambutol
embA 4245089 c.1857G>C synonymous_variant 1.0 ethambutol
embA 4245093 p.Ile621Val missense_variant 1.0 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 1.0 ethambutol
embA 4245125 c.1893G>C synonymous_variant 1.0 ethambutol
embA 4245137 c.1905T>C synonymous_variant 1.0 ethambutol
embB 4247425 c.912G>C synonymous_variant 1.0 ethambutol
embB 4247437 c.924A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247452 c.939C>G synonymous_variant 1.0 ethambutol
embB 4247470 c.957T>C synonymous_variant 1.0 ethambutol
embB 4247497 c.984T>C synonymous_variant 1.0 ethambutol
embB 4247500 c.987C>G synonymous_variant 1.0 ethambutol
embB 4247506 c.993C>G synonymous_variant 1.0 ethambutol
embB 4247512 c.999T>C synonymous_variant 1.0 ethambutol
embB 4247527 c.1014G>C synonymous_variant 1.0 ethambutol
embB 4247539 c.1026T>C synonymous_variant 1.0 ethambutol
embB 4247550 p.Ala346Asp missense_variant 1.0 ethambutol
embB 4247554 c.1041T>C synonymous_variant 1.0 ethambutol
embB 4247566 c.1053C>G synonymous_variant 1.0 ethambutol
embB 4247572 c.1059A>C synonymous_variant 1.0 ethambutol
embB 4247590 c.1077A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 1.0 ethambutol
embB 4247677 c.1164C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4247684 c.1171T>C synonymous_variant 1.0 ethambutol
embB 4247722 c.1209G>T synonymous_variant 1.0 ethambutol
embB 4247725 c.1212G>C synonymous_variant 1.0 ethambutol
embB 4247729 p.Gly406Pro missense_variant 1.0 ethambutol
embB 4247753 p.Val414Ile missense_variant 1.0 ethambutol Uncertain significance
embB 4248007 c.1494C>A synonymous_variant 1.0 ethambutol
embB 4248035 p.Val508Ile missense_variant 1.0 ethambutol
embB 4248041 p.Ala510Thr missense_variant 1.0 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 1.0 ethambutol
embB 4248055 c.1542G>C synonymous_variant 1.0 ethambutol
embB 4248064 c.1551G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 1.0 ethambutol
embB 4248085 c.1572T>C synonymous_variant 1.0 ethambutol
embB 4248097 c.1584C>G synonymous_variant 1.0 ethambutol
embB 4248118 c.1605T>G synonymous_variant 1.0 ethambutol
embB 4248127 c.1614G>C synonymous_variant 1.0 ethambutol
embB 4248130 c.1617G>C synonymous_variant 1.0 ethambutol
embB 4248133 c.1620C>A synonymous_variant 1.0 ethambutol
embB 4248139 c.1626C>G synonymous_variant 1.0 ethambutol
embB 4248142 c.1629T>C synonymous_variant 1.0 ethambutol
embB 4248143 c.1630T>C synonymous_variant 1.0 ethambutol
embB 4248146 c.1633_1635delATCinsCG frameshift_variant&missense_variant 1.0 ethambutol
embB 4248149 p.Thr546Ser missense_variant 1.0 ethambutol
embB 4248157 c.1644A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248161 c.1648C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248169 c.1656C>G synonymous_variant 1.0 ethambutol
embB 4248190 c.1677G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embB 4248200 p.Ile563Val missense_variant 1.0 ethambutol
embB 4248206 p.Ser565Gly missense_variant 1.0 ethambutol Uncertain significance
embB 4248211 c.1698G>A synonymous_variant 1.0 ethambutol
embB 4248220 c.1707A>C synonymous_variant 1.0 ethambutol
embB 4248241 c.1728C>T synonymous_variant 1.0 ethambutol
embB 4248277 c.1764G>C synonymous_variant 1.0 ethambutol
embB 4248298 c.1785C>T synonymous_variant 1.0 ethambutol