TB-Profiler result

Run: ERR124636

Summary

Run ID: ERR124636

Sample name:

Date: 2024-10-04T01:36:20.603814

Number of reads: 836590

Percentage reads mapped: 7.5

Median coverage: 0.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.96
lineage4.9 Euro-American (H37Rv-like) None 0.83
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 693 c.693A>C synonymous_variant 1.0 isoniazid
dnaA 702 c.702C>G synonymous_variant 1.0 isoniazid
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 0.96 isoniazid
dnaA 753 c.753C>T synonymous_variant 0.96 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.96 isoniazid
dnaA 767 p.Val256Ala missense_variant 0.96 isoniazid
dnaA 769 p.Ala257Ser missense_variant 0.96 isoniazid Uncertain significance
dnaA 783 c.783C>T synonymous_variant 0.96 isoniazid Not assoc w R - Interim
dnaA 1220 p.Asn407Thr missense_variant 1.0 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 1.0 isoniazid
dnaA 1236 c.1236C>T synonymous_variant 1.0 isoniazid
dnaA 1237 p.Ala413Thr missense_variant 1.0 isoniazid Uncertain significance
dnaA 1243 p.Thr415Ala missense_variant 1.0 isoniazid Uncertain significance
dnaA 1254 c.1254T>G synonymous_variant 1.0 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 1.0 isoniazid
dnaA 1275 p.Asp425Glu missense_variant 1.0 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 1.0 isoniazid
dnaA 1281 c.1281C>G synonymous_variant 1.0 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 1.0 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 1.0 isoniazid
dnaA 1314 c.1314A>T synonymous_variant 1.0 isoniazid
dnaA 1317 c.1317A>G synonymous_variant 1.0 isoniazid
dnaA 1329 c.1329A>C synonymous_variant 1.0 isoniazid
dnaA 1332 c.1332A>T synonymous_variant 1.0 isoniazid
dnaA 1338 c.1338T>C synonymous_variant 1.0 isoniazid
dnaA 1341 c.1341G>C synonymous_variant 1.0 isoniazid
dnaA 1347 c.1347C>T synonymous_variant 1.0 isoniazid
dnaA 1353 c.1353T>C synonymous_variant 1.0 isoniazid
dnaA 1356 c.1356T>A synonymous_variant 1.0 isoniazid
gyrB 5320 c.81C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5326 c.87T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5329 c.90C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5341 c.102T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5344 c.105C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5347 c.108G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5359 c.120C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 5363 c.124_126delTTAinsCTG synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5374 c.135C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5377 c.138T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 5386 c.147G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 5389 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6086 p.Thr283Pro missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6097 c.858G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6100 c.861G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6109 c.870G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6123 p.Ala295Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6130 c.891T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6133 c.894G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6175 c.936G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6181 c.942C>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6184 c.945C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6196 c.957C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 6532 c.-770C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6547 c.-755T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6550 c.-752A>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6551 c.1312T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6571 c.-731T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6577 c.1338T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6583 c.-719G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6589 c.-713G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6601 c.-701A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6607 c.-695T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6628 c.-674C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6685 c.-617C>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6727 c.-575G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6808 c.1569C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6811 c.1572C>T synonymous_variant 0.98 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 6838 c.-464C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6841 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6844 c.-458T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6853 c.-449A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6856 c.1617T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6859 c.1620T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6869 c.-433T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6872 c.-430_-428delTTGinsCTC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6878 c.1639T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6881 c.-421_-419delTTGinsCTC upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6896 p.Arg553Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6910 c.-392G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6911 p.Asn558His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6916 c.-386G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6919 c.1680T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6925 c.-377T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6926 c.1687T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6931 c.-371A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6934 c.-368A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6963 c.1724_1725insT frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6966 c.1728delT frameshift_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6970 p.Asp577Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7075 c.-227T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7078 c.-224A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7081 c.-221T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7090 c.-212C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7100 c.1861T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7108 c.-194G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7123 c.-179C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7126 c.-176G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7159 c.1920C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7162 c.1923C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7165 c.-137C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7168 c.-134C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7210 p.Asp657Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7234 c.1995C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7343 c.42G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7355 c.54T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7397 c.96G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7406 c.105G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7418 c.117C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>A synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7442 c.141G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7463 c.162G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7565 c.264C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 0.99 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7601 c.300C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7613 c.312G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7622 c.321C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 7709 c.408G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7739 c.438C>T synonymous_variant 0.98 levofloxacin
moxifloxacin Not assoc w R - Interim
gyrA 7763 c.462T>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7769 c.468C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7784 c.483A>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7796 c.495G>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7802 c.501C>G synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7859 c.558A>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 7886 c.585T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7901 c.600G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7906 p.Phe202Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8174 c.873C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8191 p.Ala297Gly missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8210 c.909G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 p.Ile328Leu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8327 c.1026C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8354 c.1053G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8366 c.1065G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8372 c.1071G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8408 c.1107A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8433 p.Thr378Arg missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8456 c.1155C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8471 c.1170T>C synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8510 c.1209G>A synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8513 c.1212C>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.96 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 8535 p.Glu412Gln missense_variant 0.95 levofloxacin
moxifloxacin
gyrA 8546 p.Asp415Glu missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8571 c.1270C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8810 c.1509A>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8816 c.1515C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8840 c.1539C>T synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.99 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8876 c.1575C>T synonymous_variant 0.99 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9213 p.Thr638Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9251 c.1950G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9324 c.2023_2025delTCGinsAGT synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044_2046delAGGinsCGC synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9353 c.2052G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9407 c.2106C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9419 c.2118T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9420 p.Ile707Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9644 c.2343T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9650 c.2349G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9656 c.2355C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9662 c.2361G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9668 c.2367C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 9683 c.2382G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9689 c.2388G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9701 c.2400T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9707 c.2406G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9716 c.2415T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9738 p.Leu813Ile missense_variant 0.94 levofloxacin
moxifloxacin
gyrA 9743 c.2442C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9746 c.2445C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 491043 c.261T>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491049 c.267T>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491055 c.273C>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491064 c.282A>G synonymous_variant 0.92 pretomanid
delamanid
clofazimine
fgd1 491067 c.285C>T synonymous_variant 0.92 pretomanid
delamanid
clofazimine Not assoc w R - Interim
fgd1 491073 c.291C>T synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491077 p.Asn99Gly missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491082 c.300T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491085 c.303T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491091 c.309T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491115 c.333G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491121 c.339A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491133 c.351A>C synonymous_variant 0.46 pretomanid
delamanid
clofazimine
fgd1 491137 p.GluGlyAla119IleGlyGlu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491166 c.384G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491184 c.402A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491259 c.477T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491283 p.Asp167Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491286 c.504G>C synonymous_variant 0.98 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491290 p.Val170Ile missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491295 c.513C>G synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491310 c.528C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491313 c.531C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491316 c.534C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491321 p.Ala180Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491346 c.564C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491349 c.567T>C synonymous_variant 1.0 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fgd1 491364 c.582T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491367 c.585G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491499 c.717G>C synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fgd1 491500 p.Glu240Lys missense_variant 0.95 pretomanid
delamanid
clofazimine
fgd1 491508 c.726A>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fgd1 491512 p.Asn244Glu missense_variant 0.97 pretomanid
delamanid
clofazimine
fgd1 491523 c.741G>C synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fgd1 491526 c.744T>C synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fgd1 491542 c.760T>C synonymous_variant 0.99 pretomanid
delamanid
clofazimine
fgd1 491547 c.765A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491563 c.781_783delAGCinsTCG synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491595 c.813C>T synonymous_variant 0.99 pretomanid
delamanid
clofazimine
fgd1 491610 c.828A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491616 c.834A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491620 p.Ile280Val missense_variant 1.0 pretomanid
delamanid
clofazimine
fgd1 491649 c.867C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
mshA 575659 c.312A>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575662 c.315C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575689 c.342G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575692 c.345G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575704 c.357T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575705 c.358T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575725 c.378C>G synonymous_variant 0.98 isoniazid
ethionamide
mshA 575734 c.387T>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575744 p.Ala133Thr missense_variant 1.0 isoniazid Uncertain significance
ethionamide
mshA 575749 c.402C>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575764 c.417C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575771 p.Val142Thr missense_variant 1.0 isoniazid
ethionamide
mshA 575776 c.429C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575782 c.435G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575785 c.438T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575795 p.Ile150Val missense_variant 1.0 isoniazid
ethionamide
mshA 575800 c.453G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575803 c.456C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
mshA 575821 c.474G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575842 c.495G>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575864 c.517T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575893 c.546C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575905 c.558G>A synonymous_variant 0.94 isoniazid
ethionamide
mshA 575906 p.Ala187Ser missense_variant 1.0 isoniazid
ethionamide
mshA 575916 p.Asp190Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575920 c.573C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575929 c.582C>G synonymous_variant 1.0 isoniazid
ethionamide
mshA 575935 c.588G>A synonymous_variant 1.0 isoniazid
ethionamide
mshA 575939 c.592C>T synonymous_variant 1.0 isoniazid
ethionamide
mshA 575944 c.597T>C synonymous_variant 1.0 isoniazid
ethionamide
mshA 575945 p.Thr200Ala missense_variant 1.0 isoniazid
ethionamide
mshA 575950 c.603C>G synonymous_variant 1.0 isoniazid
ethionamide
ccsA 620307 c.417C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620311 p.Leu141Val missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620316 c.426G>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin
amikacin Not assoc w R - Interim
ccsA 620340 c.450C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620346 c.456C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620356 c.466_468delCTCinsTTG synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620362 p.Ala158Ser missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620367 c.477T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620385 c.495G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620388 c.498A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620397 c.507C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620412 c.522T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620415 c.525T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
ccsA 620421 c.531G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620427 c.537C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620436 c.546T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620439 c.549T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620442 c.552G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620445 c.555A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620454 c.564C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620463 c.573C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620598 c.708C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620604 c.714C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620605 p.Val239Ile missense_variant 1.0 kanamycin Uncertain significance
capreomycin
amikacin Uncertain significance
ccsA 620619 c.729G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620631 c.741T>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620649 c.759A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620652 c.762C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620661 c.771C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620670 c.780C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620694 c.804C>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620698 p.Val270Ile missense_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620715 c.825C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620730 c.840C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620733 c.843G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620736 c.846G>A synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620739 c.849A>G synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620742 c.852G>C synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620757 c.867C>T synonymous_variant 1.0 kanamycin
capreomycin
amikacin
ccsA 620764 p.Ala292Ser missense_variant 1.0 kanamycin
capreomycin
amikacin
Rv0565c 657601 c.-131A>T upstream_gene_variant 0.83 ethionamide
Rv0565c 657636 c.-167_-166delAGinsTC upstream_gene_variant 0.95 ethionamide
Rv0565c 657639 c.-169C>G upstream_gene_variant 0.95 ethionamide
Rv0565c 657649 c.-179G>A upstream_gene_variant 0.96 ethionamide
Rv0565c 657670 c.-200A>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 0.96 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 0.97 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.99 ethionamide
Rv0565c 657703 c.-233C>A upstream_gene_variant 0.98 ethionamide
Rv0565c 657722 c.-254_-252delAACinsCAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
hadA 731732 c.-198G>A upstream_gene_variant 1.0 isoniazid
hadA 731753 c.-177A>G upstream_gene_variant 1.0 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 1.0 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 1.0 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 1.0 isoniazid
hadA 731810 c.-120G>C upstream_gene_variant 1.0 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 1.0 isoniazid
hadA 731823 c.-107_-105delCTGinsATC upstream_gene_variant 1.0 isoniazid
hadA 731840 c.-90G>C upstream_gene_variant 1.0 isoniazid
hadA 732238 c.309G>C synonymous_variant 1.0 isoniazid
hadA 732241 c.312C>T synonymous_variant 1.0 isoniazid
hadA 732250 c.321C>G synonymous_variant 1.0 isoniazid
hadA 732257 p.Asp110His missense_variant 1.0 isoniazid
hadA 732262 c.333G>C synonymous_variant 1.0 isoniazid
hadA 732268 c.339T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
hadA 732269 p.Glu114Lys missense_variant 1.0 isoniazid
hadA 732284 p.Gln119Asp missense_variant 1.0 isoniazid
hadA 732308 p.Val127Ile missense_variant 1.0 isoniazid
hadA 732314 p.Asn129Asp missense_variant 1.0 isoniazid
hadA 732319 p.Glu130Asp missense_variant 1.0 isoniazid
hadA 732320 p.Glu131Lys missense_variant 1.0 isoniazid
hadA 732329 p.Leu134Val missense_variant 1.0 isoniazid Uncertain significance
hadA 732334 c.405G>C synonymous_variant 1.0 isoniazid
hadA 732341 p.Thr138Ala missense_variant 1.0 isoniazid
hadA 732346 c.417T>C synonymous_variant 1.0 isoniazid
nusG 734407 p.Val52Ile missense_variant 0.8 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.96 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.96 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.98 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.97 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.97 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.97 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.99 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
nusG 734571 c.318C>G synonymous_variant 1.0 rifampicin
nusG 734580 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734589 c.336G>C synonymous_variant 1.0 rifampicin
nusG 734841 c.588G>C synonymous_variant 0.91 rifampicin
nusG 734847 c.594T>C synonymous_variant 0.91 rifampicin
nusG 734850 c.597C>G synonymous_variant 1.0 rifampicin
nusG 734853 c.600A>G synonymous_variant 1.0 rifampicin
nusG 734854 c.601T>C synonymous_variant 1.0 rifampicin
nusG 734859 c.606G>C synonymous_variant 1.0 rifampicin
nusG 734863 p.Thr204Ser missense_variant 1.0 rifampicin
nusG 734886 c.633A>G synonymous_variant 1.0 rifampicin
rpoB 760082 c.276C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760088 c.282C>G synonymous_variant 1.0 rifampicin
rpoB 760091 c.285G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760104 c.298_300delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.96 rifampicin
rpoB 760118 c.312T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760136 c.330G>A synonymous_variant 1.0 rifampicin
rpoB 760139 c.333A>T synonymous_variant 1.0 rifampicin
rpoB 760142 c.336C>G synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760325 c.519G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760331 c.525G>C synonymous_variant 1.0 rifampicin
rpoB 760334 c.528G>T synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760357 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760463 c.657C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760585 p.Asn260Ser missense_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760595 c.789C>T synonymous_variant 1.0 rifampicin
rpoB 760596 p.Thr264Pro missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 1.0 rifampicin
rpoB 760751 c.945G>C synonymous_variant 0.96 rifampicin
rpoB 760755 p.His317Asn missense_variant 1.0 rifampicin
rpoB 760759 p.Val318Ala missense_variant 1.0 rifampicin
rpoB 760764 p.Glu320Gln missense_variant 1.0 rifampicin
rpoB 760769 c.963C>G synonymous_variant 1.0 rifampicin
rpoB 760784 c.978G>T synonymous_variant 0.98 rifampicin
rpoB 760793 c.987A>G synonymous_variant 1.0 rifampicin
rpoB 760805 c.999G>C synonymous_variant 1.0 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 1.0 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 1.0 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760859 c.1053T>C synonymous_variant 1.0 rifampicin
rpoB 760862 c.1056G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760877 c.1071G>C synonymous_variant 1.0 rifampicin
rpoB 760883 c.1077G>C synonymous_variant 1.0 rifampicin
rpoB 760886 c.1080A>G synonymous_variant 1.0 rifampicin
rpoB 760887 p.Thr361Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 760910 c.1104C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760919 c.1113C>T synonymous_variant 1.0 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760958 c.1152G>C synonymous_variant 1.0 rifampicin
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760997 c.1191G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761111 c.1305C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761213 c.1407G>C synonymous_variant 1.0 rifampicin
rpoB 761217 p.Pro471Ser missense_variant 1.0 rifampicin
rpoB 761234 c.1428G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 0.99 rifampicin
rpoB 761288 c.1482G>T synonymous_variant 0.99 rifampicin
rpoB 761318 c.1512G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 761330 c.1524G>C synonymous_variant 0.99 rifampicin
rpoB 761345 c.1539G>C synonymous_variant 0.98 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.98 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.98 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 0.98 rifampicin
rpoB 761374 p.Val523Asp missense_variant 0.98 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.98 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.96 rifampicin
rpoB 761435 c.1629T>C synonymous_variant 0.9 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761552 c.1746G>C synonymous_variant 1.0 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761708 c.1902C>T synonymous_variant 1.0 rifampicin
rpoB 761712 p.Val636Ile missense_variant 1.0 rifampicin
rpoB 761736 p.Ile644Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 1.0 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 1.0 rifampicin
rpoB 761785 p.Thr660Ser missense_variant 1.0 rifampicin
rpoB 761791 p.Arg662His missense_variant 1.0 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 1.0 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 1.0 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761867 c.2061C>G synonymous_variant 1.0 rifampicin
rpoB 761868 p.Asp688Gln missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>T synonymous_variant 1.0 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.97 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.97 rifampicin
rpoB 761892 p.Ile696Val missense_variant 0.97 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.95 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.95 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.95 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 0.95 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.95 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.96 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.95 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761954 c.2148C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762014 c.2208C>T synonymous_variant 0.99 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762284 c.2478G>T synonymous_variant 0.99 rifampicin
rpoB 762287 c.2481C>T synonymous_variant 1.0 rifampicin
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762350 c.2544C>T synonymous_variant 1.0 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.99 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.99 rifampicin Uncertain significance
rpoB 762515 c.2709C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762533 c.-837T>C upstream_gene_variant 1.0 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 1.0 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 1.0 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 1.0 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 1.0 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 1.0 rifampicin
rpoB 762812 c.3006C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762814 p.Met1003Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 762816 c.-554_-552delCTCinsTTG upstream_gene_variant 1.0 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 762920 c.3114C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763053 c.3247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 1.0 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763190 c.-180C>T upstream_gene_variant 1.0 rifampicin
rpoC 763199 c.-171G>C upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-163delAGinsTC upstream_gene_variant 1.0 rifampicin
rpoC 763217 c.-153G>C upstream_gene_variant 1.0 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 1.0 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 1.0 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 1.0 rifampicin
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763408 c.39T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 1.0 rifampicin
rpoC 763414 c.45T>C synonymous_variant 1.0 rifampicin
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCGT synonymous_variant 1.0 rifampicin
rpoC 763433 p.Gln22Asn missense_variant 1.0 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 1.0 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>T synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763558 c.189C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763600 c.231C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763615 c.246G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 1.0 rifampicin
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763675 c.306C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763732 c.363C>T synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763747 c.378G>A synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763792 p.Glu141Asp missense_variant 0.99 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.99 rifampicin
rpoC 763831 c.462A>G synonymous_variant 0.99 rifampicin
rpoC 763837 c.468G>C synonymous_variant 0.99 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.99 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.99 rifampicin
rpoC 763861 c.492C>T synonymous_variant 0.99 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.99 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.98 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.99 rifampicin
rpoC 763882 c.513G>A synonymous_variant 0.99 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763921 c.552G>C synonymous_variant 0.99 rifampicin
rpoC 763924 c.555G>A synonymous_variant 0.99 rifampicin
rpoC 763930 c.561G>A synonymous_variant 0.99 rifampicin
rpoC 763933 c.564C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763940 p.Ala191Ser missense_variant 0.99 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 0.96 rifampicin
rpoC 763947 p.Ala193Val missense_variant 0.95 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 0.98 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.98 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 0.98 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764040 p.Ser224Thr missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764071 c.702G>C synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764089 c.720C>G synonymous_variant 1.0 rifampicin
rpoC 764098 c.729A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764102 p.Val245Gln missense_variant 1.0 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764161 c.792G>C synonymous_variant 1.0 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764195 c.826_828delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 p.Asp279Glu missense_variant 1.0 rifampicin
rpoC 764207 p.Val280Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 764215 c.846A>C synonymous_variant 1.0 rifampicin
rpoC 764217 p.Asn283Ser missense_variant 1.0 rifampicin
rpoC 764227 c.858G>T synonymous_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764254 c.885G>C synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764266 c.897T>C synonymous_variant 1.0 rifampicin
rpoC 764272 c.903G>C synonymous_variant 1.0 rifampicin
rpoC 764278 c.909A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764293 c.924G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764297 p.Met310Leu missense_variant 1.0 rifampicin
rpoC 764344 c.975C>T synonymous_variant 1.0 rifampicin
rpoC 764353 c.984G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 1.0 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764605 c.1236G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764623 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764701 c.1332C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764716 c.1347G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764803 c.1434C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 1.0 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 1.0 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764935 c.1566T>C synonymous_variant 1.0 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1644delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765016 c.1647C>T synonymous_variant 1.0 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>C synonymous_variant 1.0 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765338 p.Gln657Lys missense_variant 1.0 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765357 p.Met663Thr missense_variant 1.0 rifampicin
rpoC 765361 c.1992C>G synonymous_variant 1.0 rifampicin
rpoC 765383 p.Met672Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 765403 c.2034G>C synonymous_variant 1.0 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 1.0 rifampicin
rpoC 765445 c.2076G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765452 p.Ala695Arg missense_variant 1.0 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765480 p.Tyr704Phe missense_variant 1.0 rifampicin Uncertain significance
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 1.0 rifampicin
rpoC 765533 p.Tyr722His missense_variant 1.0 rifampicin Uncertain significance
rpoC 765544 c.2175C>T synonymous_variant 1.0 rifampicin
rpoC 765547 c.2178C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765548 c.2179_2181delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 1.0 rifampicin
rpoC 765562 c.2193G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765577 c.2208G>T synonymous_variant 1.0 rifampicin
rpoC 765591 p.Arg741Gln missense_variant 1.0 rifampicin
rpoC 765596 p.Lys743Gln missense_variant 0.83 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 1.0 rifampicin
rpoC 765778 c.2409C>G synonymous_variant 1.0 rifampicin
rpoC 765779 p.Asp804Lys missense_variant 1.0 rifampicin
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765800 p.Phe811Leu missense_variant 1.0 rifampicin
rpoC 765811 c.2442T>G synonymous_variant 1.0 rifampicin
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765817 c.2448G>C synonymous_variant 1.0 rifampicin
rpoC 765823 c.2454C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765871 c.2502T>C synonymous_variant 1.0 rifampicin
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 765908 c.2539C>T synonymous_variant 1.0 rifampicin
rpoC 765934 c.2565C>T synonymous_variant 1.0 rifampicin
rpoC 765940 c.2571A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 1.0 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766309 c.2940G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766312 c.2943T>C synonymous_variant 0.92 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.88 rifampicin
rpoC 766345 c.2976T>C synonymous_variant 0.96 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 766363 c.2994G>C synonymous_variant 0.96 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.91 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.96 rifampicin
rpoC 766390 c.3021C>T synonymous_variant 0.95 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766675 c.3306C>T synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766694 p.Gln1109Asp missense_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766717 c.3348C>G synonymous_variant 1.0 rifampicin
rpoC 766720 c.3351C>T synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766837 c.3468G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766858 c.3489C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 1.0 rifampicin
rpoC 766867 c.3498C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>C synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766981 c.3612T>C synonymous_variant 0.99 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767008 c.3639G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767020 c.3651C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 p.Asn1246Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767138 c.3769C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767158 c.3789T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767162 p.Asn1265Ala missense_variant 0.99 rifampicin
rpoC 767167 c.3798C>T synonymous_variant 0.99 rifampicin
rpoC 767174 p.Asn1269Asp missense_variant 0.99 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.99 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 1.0 rifampicin
rpoC 767272 c.3903C>T synonymous_variant 1.0 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 1.0 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775817 c.2664T>C synonymous_variant 0.92 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
mmpL5 775835 c.2646C>G synonymous_variant 0.47 bedaquiline
clofazimine
mmpL5 775847 c.2634G>A synonymous_variant 0.42 bedaquiline
clofazimine
mmpL5 775851 p.Ser877Thr missense_variant 0.54 bedaquiline
clofazimine
mmpL5 775856 c.2625T>C synonymous_variant 0.94 bedaquiline
clofazimine
mmpL5 775862 c.2619G>C synonymous_variant 0.36 bedaquiline
clofazimine
mmpL5 775865 c.2616T>C synonymous_variant 0.98 bedaquiline
clofazimine
mmpL5 775877 c.2604C>G synonymous_variant 0.59 bedaquiline
clofazimine
mmpL5 775883 p.Ile866Leu missense_variant 0.59 bedaquiline
clofazimine
mmpL5 775886 c.2595A>G synonymous_variant 0.98 bedaquiline
clofazimine
mmpL5 775892 c.2589C>T synonymous_variant 0.68 bedaquiline
clofazimine
mmpL5 775909 p.Leu858Phe missense_variant 0.79 bedaquiline
clofazimine
mmpL5 775915 p.Ala856Ser missense_variant 0.81 bedaquiline
clofazimine
mmpL5 775916 c.2565T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 775921 c.2560C>T synonymous_variant 0.7 bedaquiline
clofazimine
mmpL5 775924 c.2557C>T synonymous_variant 0.72 bedaquiline
clofazimine Not assoc w R - Interim
mmpL5 775940 c.2541C>T synonymous_variant 0.33 bedaquiline
clofazimine
mmpL5 775951 c.2530C>T synonymous_variant 0.88 bedaquiline
clofazimine
mmpL5 775955 p.Ile842Val missense_variant 0.54 bedaquiline
clofazimine
mmpL5 775964 p.Ala839Ser missense_variant 0.46 bedaquiline
clofazimine
mmpL5 775970 c.2511G>C synonymous_variant 0.43 bedaquiline
clofazimine
mmpL5 775973 p.Leu836Ile missense_variant 0.44 bedaquiline
clofazimine
mmpL5 775981 p.Leu834Met missense_variant 1.0 bedaquiline
clofazimine
mmpL5 775994 p.Ile829Leu missense_variant 0.83 bedaquiline
clofazimine
mmpL5 775997 c.2484T>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776000 p.Leu827Ile missense_variant 0.87 bedaquiline
clofazimine
mmpL5 776005 p.Ile826Leu missense_variant 0.93 bedaquiline
clofazimine
mmpL5 776009 c.2472A>G synonymous_variant 0.67 bedaquiline
clofazimine
mmpL5 776030 c.2451G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776053 c.2428T>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776066 c.2415C>G synonymous_variant 0.4 bedaquiline
clofazimine
mmpL5 776072 c.2409C>G synonymous_variant 0.47 bedaquiline
clofazimine
mmpL5 776075 c.2406C>G synonymous_variant 0.52 bedaquiline
clofazimine
mmpL5 776081 c.2400G>C synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776084 c.2397C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776087 c.2394C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776100 p.Thr794Leu missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776120 c.2361C>T synonymous_variant 0.48 bedaquiline
clofazimine
mmpL5 776129 c.2352C>G synonymous_variant 0.43 bedaquiline
clofazimine
mmpL5 776132 p.Ala783Ser missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776135 p.Ser782Ala missense_variant 0.79 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776654 c.1827A>C synonymous_variant 0.69 bedaquiline
clofazimine
mmpL5 776664 p.Thr606Ser missense_variant 0.35 bedaquiline
clofazimine
mmpL5 776672 p.Val603Ile missense_variant 0.36 bedaquiline
clofazimine
mmpL5 776675 c.1806G>A synonymous_variant 0.45 bedaquiline
clofazimine
mmpL5 776681 p.Leu600Ile missense_variant 0.71 bedaquiline
clofazimine
mmpL5 776693 p.Val596Met missense_variant 0.71 bedaquiline
clofazimine
mmpL5 776704 p.Asp593Asn missense_variant 0.71 bedaquiline
clofazimine
mmpL5 776715 p.Lys589Pro missense_variant 1.0 bedaquiline
clofazimine
mmpL5 776728 p.Phe585Leu missense_variant 0.69 bedaquiline
clofazimine
mmpL5 776733 p.Ser583Asn missense_variant 1.0 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 776741 c.1740C>G synonymous_variant 1.0 bedaquiline
clofazimine
mmpL5 776744 c.1737C>G synonymous_variant 0.38 bedaquiline
clofazimine
mmpL5 778213 p.Ala90Ser missense_variant 0.9 bedaquiline
clofazimine
mmpL5 778225 p.Asp86His missense_variant 0.9 bedaquiline
clofazimine
mmpL5 778226 p.Gly85Phe missense_variant 0.9 bedaquiline
clofazimine
mmpL5 778232 p.Glu83Asp missense_variant 0.9 bedaquiline
clofazimine
mmpL5 778243 p.Lys80Gln missense_variant 0.9 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 778249 p.Ile78Val missense_variant 0.9 bedaquiline
clofazimine
mmpL5 778251 p.His77Arg missense_variant 0.9 bedaquiline
clofazimine
mmpR5 778253 c.-737T>C upstream_gene_variant 0.9 bedaquiline
clofazimine
mmpL5 778261 p.Ser74Ala missense_variant 0.9 bedaquiline
clofazimine
mmpL5 778267 p.Met72Val missense_variant 0.9 bedaquiline
clofazimine
mmpL5 778278 p.Ala68Glu missense_variant 0.83 bedaquiline
clofazimine
mmpL5 778286 c.195C>T synonymous_variant 0.8 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R - Interim
rpsL 781559 c.-1G>C upstream_gene_variant 1.0 streptomycin
rpsL 781572 p.Gln5Asn missense_variant 1.0 streptomycin
rpsL 781595 c.36T>C synonymous_variant 1.0 streptomycin
rpsL 781598 c.39G>C synonymous_variant 1.0 streptomycin
rpsL 781605 p.Ile16Val missense_variant 1.0 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781649 c.90T>C synonymous_variant 1.0 streptomycin
rpsL 781655 c.96T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781709 c.150G>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781732 c.174_177delGAGT frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781739 c.180_181insCGGC frameshift_variant 1.0 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781772 c.213C>T synonymous_variant 0.99 streptomycin Not assoc w R - Interim
rpsL 781808 c.249C>T synonymous_variant 0.99 streptomycin
rpsL 781814 c.255C>T synonymous_variant 0.99 streptomycin
rpsL 781817 c.258G>T synonymous_variant 0.99 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.99 streptomycin
rpsL 781832 c.273T>C synonymous_variant 0.99 streptomycin
rpsL 781838 c.279G>C synonymous_variant 0.99 streptomycin
rpsL 781841 c.282C>T synonymous_variant 0.99 streptomycin
rpsL 781859 c.300T>G synonymous_variant 0.98 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.98 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.99 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.99 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.99 streptomycin
rpsL 781898 c.339A>C synonymous_variant 0.99 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.99 streptomycin
rpsL 781907 c.348T>C synonymous_variant 0.99 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.99 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.98 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800543 c.-266C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.99 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>G upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 0.96 linezolid
rplC 800603 c.-206G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 1.0 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 1.0 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>G synonymous_variant 1.0 linezolid
rplC 800921 p.Arg38Leu missense_variant 1.0 linezolid
rplC 800928 c.120C>T synonymous_variant 0.97 linezolid
rplC 800931 c.123G>C synonymous_variant 0.97 linezolid
rplC 800937 c.129A>G synonymous_variant 0.97 linezolid
rplC 800946 c.138T>C synonymous_variant 0.97 linezolid
rplC 800949 c.141T>C synonymous_variant 0.98 linezolid
rplC 800964 c.156G>C synonymous_variant 0.98 linezolid
rplC 800985 c.177A>G synonymous_variant 0.98 linezolid
rplC 801003 c.195G>C synonymous_variant 0.96 linezolid
rplC 801004 p.Leu66Val missense_variant 0.95 linezolid
rplC 801009 c.201A>C synonymous_variant 0.95 linezolid
rplC 801012 c.204T>C synonymous_variant 0.95 linezolid
rplC 801019 p.Thr71Ala missense_variant 0.95 linezolid
rplC 801027 c.219C>G synonymous_variant 1.0 linezolid
rplC 801039 c.231A>G synonymous_variant 1.0 linezolid
rplC 801171 c.363A>G synonymous_variant 1.0 linezolid
rplC 801174 c.366T>C synonymous_variant 1.0 linezolid
rplC 801195 c.387G>T synonymous_variant 1.0 linezolid
rplC 801205 p.Arg133Ala missense_variant 1.0 linezolid
rplC 801210 c.402T>C synonymous_variant 1.0 linezolid
rplC 801220 p.Ser138Ala missense_variant 1.0 linezolid
rplC 801231 c.423C>T synonymous_variant 1.0 linezolid
rplC 801237 c.429G>A synonymous_variant 1.0 linezolid
rplC 801252 c.444G>C synonymous_variant 1.0 linezolid
rplC 801264 c.456C>T synonymous_variant 1.0 linezolid
rplC 801267 c.459A>C synonymous_variant 1.0 linezolid
rplC 801276 c.468G>C synonymous_variant 1.0 linezolid
rplC 801281 p.Ala158Gly missense_variant 1.0 linezolid
rplC 801285 c.477G>C synonymous_variant 1.0 linezolid
rplC 801307 p.Ala167Ser missense_variant 1.0 linezolid
rplC 801312 c.504G>C synonymous_variant 1.0 linezolid
rplC 801315 c.507G>T synonymous_variant 1.0 linezolid
rplC 801324 c.516T>C synonymous_variant 1.0 linezolid
fbiC 1303509 c.579G>C synonymous_variant 0.68 pretomanid
delamanid
clofazimine
fbiC 1303512 c.582T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303531 p.Met201Leu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303536 c.606G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303539 c.609G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303545 c.615A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303548 c.618G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303551 c.621G>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303554 c.624G>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303581 c.651G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303584 c.654C>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303587 c.657G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303593 c.663G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303602 c.672A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303611 c.681G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303612 p.Leu228Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303629 c.699C>T synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1303632 c.702T>C synonymous_variant 0.95 pretomanid
delamanid
clofazimine
fbiC 1303644 c.714G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304505 c.1575G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304515 p.Ala529Thr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304526 c.1596T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304533 c.1603T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304541 c.1611C>A synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304544 c.1614T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304546 p.Val539Ala missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304559 p.Glu543Asp missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304562 c.1632G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304567 p.Phe546Tyr missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304571 c.1641G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304580 c.1650T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304613 c.1683T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304634 c.1704C>G synonymous_variant 0.99 pretomanid
delamanid
clofazimine
fbiC 1304640 c.1710A>C synonymous_variant 0.99 pretomanid
delamanid
clofazimine
fbiC 1304646 c.1716T>C synonymous_variant 0.99 pretomanid
delamanid
clofazimine
fbiC 1304670 c.1740G>C synonymous_variant 0.99 pretomanid
delamanid
clofazimine
fbiC 1304671 p.Val581Thr missense_variant 0.98 pretomanid
delamanid
clofazimine
fbiC 1304675 p.Gly582Asp missense_variant 0.99 pretomanid
delamanid
clofazimine
fbiC 1304694 c.1764A>G synonymous_variant 0.99 pretomanid
delamanid
clofazimine
fbiC 1304715 c.1785G>T synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fbiC 1304724 c.1794A>G synonymous_variant 0.97 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fbiC 1304742 c.1812T>C synonymous_variant 0.98 pretomanid
delamanid
clofazimine
fbiC 1304751 c.1821C>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304757 c.1827A>G synonymous_variant 0.97 pretomanid
delamanid
clofazimine
fbiC 1304760 c.1830G>C synonymous_variant 0.94 pretomanid
delamanid
clofazimine
fbiC 1304769 c.1839C>G synonymous_variant 0.96 pretomanid
delamanid
clofazimine
fbiC 1304772 c.1842C>T synonymous_variant 0.96 pretomanid
delamanid Not assoc w R - Interim
clofazimine Not assoc w R - Interim
fbiC 1304958 c.2028T>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304991 c.2061G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304994 c.2064A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1304995 p.Leu689Glu missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305004 p.Glu692Asn missense_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305007 p.Ile693Val missense_variant 1.0 pretomanid
delamanid Uncertain significance
clofazimine Uncertain significance
fbiC 1305015 c.2085G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305033 c.2103T>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305039 c.2109G>C synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305042 c.2112A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
fbiC 1305045 c.2115A>G synonymous_variant 1.0 pretomanid
delamanid
clofazimine
sigE 1364640 c.228G>C synonymous_variant 0.94 pyrazinamide
sigE 1364643 c.231C>T synonymous_variant 0.94 pyrazinamide
sigE 1364644 p.Lys78Gln missense_variant 0.94 pyrazinamide
sigE 1364650 p.Thr80Ala missense_variant 0.96 pyrazinamide Uncertain significance
sigE 1364661 c.249C>A synonymous_variant 0.98 pyrazinamide
sigE 1364682 c.270G>A synonymous_variant 0.99 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.99 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 1.0 pyrazinamide
sigE 1364778 c.366G>C synonymous_variant 1.0 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364796 c.384G>A synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364814 c.402C>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.98 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.97 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.97 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 0.97 pyrazinamide
sigE 1364871 c.459C>T synonymous_variant 0.97 pyrazinamide
sigE 1364877 c.465G>T synonymous_variant 0.97 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.98 pyrazinamide
sigE 1364887 c.475_477delTTAinsCTG synonymous_variant 0.98 pyrazinamide
sigE 1364898 c.486C>T synonymous_variant 0.98 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.97 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.97 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 1.0 pyrazinamide
sigE 1364931 c.519C>T synonymous_variant 1.0 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 1.0 pyrazinamide
sigE 1364956 c.544C>T synonymous_variant 1.0 pyrazinamide
sigE 1364962 p.Pro184Ala missense_variant 1.0 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
atpE 1461132 p.Val30Ile missense_variant 0.88 bedaquiline
atpE 1461137 c.93C>G synonymous_variant 0.88 bedaquiline
atpE 1461149 c.105T>G synonymous_variant 0.94 bedaquiline
atpE 1461155 c.111C>G synonymous_variant 0.93 bedaquiline
atpE 1461159 p.Val39Ile missense_variant 0.93 bedaquiline Uncertain significance
atpE 1461167 c.123G>T synonymous_variant 0.94 bedaquiline
atpE 1461170 c.126A>G synonymous_variant 0.95 bedaquiline
atpE 1461179 c.135G>C synonymous_variant 0.95 bedaquiline
atpE 1461182 c.138A>G synonymous_variant 0.95 bedaquiline
atpE 1461185 c.141G>C synonymous_variant 0.98 bedaquiline
atpE 1461197 c.153A>C synonymous_variant 1.0 bedaquiline
atpE 1461219 c.175T>C synonymous_variant 1.0 bedaquiline
atpE 1461224 c.180T>G synonymous_variant 1.0 bedaquiline
atpE 1461227 c.183G>A synonymous_variant 0.98 bedaquiline
atpE 1461230 c.186G>C synonymous_variant 0.97 bedaquiline
atpE 1461233 c.189A>G synonymous_variant 1.0 bedaquiline
atpE 1461251 c.207G>C synonymous_variant 1.0 bedaquiline
atpE 1461254 c.210T>C synonymous_variant 1.0 bedaquiline
rrs 1471845 n.-1G>T upstream_gene_variant 0.83 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.99 kanamycin
capreomycin
streptomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472041 n.196C>T non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.95 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Not assoc w R
streptomycin Uncertain significance
amikacin Not assoc w R
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472846 n.1001C>A non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.99 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.98 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin
amikacin Uncertain significance
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 kanamycin Uncertain significance
capreomycin Uncertain significance
streptomycin Uncertain significance
amikacin Uncertain significance
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473696 n.39T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473697 n.40C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473811 n.154_155insT non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473814 n.158delT non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473829 n.172G>T non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsAA non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473935 n.278C>T non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473945 n.288T>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473946 n.289A>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474091 n.434C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1474096 n.439C>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1474102 n.446_449delAGTA non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474108 n.451C>G non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474110 n.453_454insCGGTG non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474716 n.1059_1063delAAAGCinsCCAAGAGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.92 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.95 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.96 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.99 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.99 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476747 n.3090C>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476754 n.3097G>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
inhA 1673703 c.-499C>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673708 c.-493_-492delCC upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673714 c.-488_-487insT upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673717 c.-485_-484insA upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673724 c.-478A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673730 c.-472C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673745 c.-457G>A upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673748 c.-454A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673749 c.-453_-452delAAinsCG upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673760 c.-442G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673778 c.-424C>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673784 c.-418G>T upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673787 c.-415G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673799 c.-403T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673802 c.-400A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1673808 c.-394A>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674006 c.-196T>G upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674037 c.-165_-164delCAinsGC upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674042 c.-160G>C upstream_gene_variant 1.0 isoniazid Uncertain significance
ethionamide
inhA 1674045 c.-157G>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674049 c.-153_-151delCAAinsGAC upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674060 c.-142A>C upstream_gene_variant 1.0 isoniazid
ethionamide
inhA 1674331 p.Leu44Met missense_variant 1.0 isoniazid
ethionamide
inhA 1674334 p.Arg45Lys missense_variant 1.0 isoniazid
ethionamide
inhA 1674342 c.141T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674352 p.Thr51Ala missense_variant 1.0 isoniazid
ethionamide Uncertain significance
inhA 1674361 c.160C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674365 c.165_166delGG frameshift_variant 1.0 isoniazid
ethionamide
inhA 1674371 c.170delAinsGCC frameshift_variant&missense_variant 1.0 isoniazid
ethionamide
inhA 1674375 c.174C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674384 c.183C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674399 c.198A>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674522 c.321G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674534 c.333G>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674537 c.336C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674543 c.342G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674549 c.348G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674550 p.Ser117Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674573 c.372G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674576 c.375T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674579 c.378G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674582 c.381T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674585 c.384T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674589 p.Met130Leu missense_variant 1.0 isoniazid
ethionamide
inhA 1674600 c.399G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674601 p.Leu134Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674651 c.450C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674656 p.Ser152Thr missense_variant 1.0 isoniazid
ethionamide
inhA 1674660 c.459G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674663 c.462G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674672 c.471C>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674690 c.489C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674702 c.501G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674703 c.502_504delTTGinsCTC synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674718 c.517A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674729 c.528G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674742 p.Lys181Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674745 p.Tyr182Ala missense_variant 1.0 isoniazid
ethionamide
inhA 1674753 c.552G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674774 c.573A>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674777 c.576C>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674780 c.579T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674789 c.588G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674792 c.591G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674795 c.594G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674801 c.600T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674804 c.603G>C synonymous_variant 1.0 isoniazid
ethionamide Not assoc w R - Interim
inhA 1674855 c.654C>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674858 c.657G>A synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674876 c.675C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674879 c.678T>G synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674904 p.Ala235Pro missense_variant 1.0 isoniazid
ethionamide
inhA 1674924 c.723G>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674930 c.729C>T synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674934 c.733C>T synonymous_variant 0.98 isoniazid
ethionamide
inhA 1674942 c.741T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674949 p.Leu250Met missense_variant 1.0 isoniazid
ethionamide
inhA 1674954 c.753G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674957 c.756G>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674963 c.762G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
ethionamide
inhA 1674966 c.765T>C synonymous_variant 1.0 isoniazid
ethionamide
inhA 1674967 p.Asp256Thr missense_variant 1.0 isoniazid
ethionamide
rpsA 1833547 c.6G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>T synonymous_variant 0.98 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833730 c.189C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833733 c.192C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 0.99 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.99 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833976 c.435C>T synonymous_variant 0.99 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.99 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 p.Asn205Gln missense_variant 1.0 pyrazinamide
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834168 c.627C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834246 c.705G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834252 c.711C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834297 c.756C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834345 c.804C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834396 c.855G>T synonymous_variant 0.99 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 0.99 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.96 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 0.99 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.98 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834756 c.1215G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 1.0 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834774 c.1233C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 1.0 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834829 p.Ala430Thr missense_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTCG upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>T upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 1.0 linezolid
ndh 2102638 c.405A>T synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102644 c.399A>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102668 c.375T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102671 c.372T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102677 c.366C>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102680 c.363T>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102683 c.360T>G synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102686 c.357G>A synonymous_variant 1.0 isoniazid
delamanid
ethionamide
ndh 2102694 p.Val117Ile missense_variant 1.0 isoniazid Uncertain significance
delamanid Uncertain significance
ethionamide Uncertain significance
ndh 2102698 c.345G>C synonymous_variant 1.0 isoniazid
delamanid
ethionamide
katG 2155659 p.Val151Leu missense_variant 1.0 isoniazid
katG 2155668 c.444G>C synonymous_variant 1.0 isoniazid
katG 2155674 c.438G>C synonymous_variant 1.0 isoniazid
katG 2155680 c.432G>A synonymous_variant 1.0 isoniazid
katG 2155691 c.421T>C synonymous_variant 1.0 isoniazid
katG 2155696 p.Ala139Val missense_variant 1.0 isoniazid
katG 2155716 c.396T>G synonymous_variant 1.0 isoniazid
katG 2155722 c.390G>C synonymous_variant 1.0 isoniazid
katG 2155728 c.384G>C synonymous_variant 1.0 isoniazid
katG 2155742 p.Gly124Arg missense_variant 1.0 isoniazid
katG 2155747 p.Ala122Gly missense_variant 1.0 isoniazid
katG 2155749 c.363C>T synonymous_variant 0.94 isoniazid Not assoc w R - Interim
katG 2155752 c.360C>T synonymous_variant 1.0 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517980 c.-135C>T upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 1.0 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 1.0 isoniazid
kasA 2518564 c.450C>G synonymous_variant 0.91 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.91 isoniazid
kasA 2518573 c.459G>C synonymous_variant 0.91 isoniazid
kasA 2518574 p.Ile154Ala missense_variant 0.91 isoniazid
kasA 2518582 c.468G>C synonymous_variant 0.91 isoniazid
kasA 2518583 p.Gln157Glu missense_variant 0.91 isoniazid
kasA 2518588 c.474T>C synonymous_variant 0.91 isoniazid
kasA 2518591 c.477G>C synonymous_variant 0.91 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518612 c.498C>T synonymous_variant 1.0 isoniazid
kasA 2518624 c.510C>G synonymous_variant 1.0 isoniazid
kasA 2518636 c.522C>A synonymous_variant 1.0 isoniazid
kasA 2518639 c.525G>T synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518656 p.Ala181Gly missense_variant 1.0 isoniazid
kasA 2518663 c.549T>C synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518684 c.570C>G synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Phe missense_variant 1.0 isoniazid
kasA 2518697 p.Cys195Val missense_variant 1.0 isoniazid
kasA 2518708 c.594C>G synonymous_variant 0.95 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.93 isoniazid
kasA 2518715 p.Pro201Gly missense_variant 0.94 isoniazid
kasA 2518726 c.612G>A synonymous_variant 0.97 isoniazid
kasA 2518732 c.618C>G synonymous_variant 0.97 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.98 isoniazid
kasA 2518756 c.642G>C synonymous_variant 0.98 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 0.98 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.98 isoniazid
kasA 2518785 p.Glu224Ala missense_variant 0.98 isoniazid
kasA 2518787 p.Arg225Gly missense_variant 0.98 isoniazid
kasA 2518792 c.678C>G synonymous_variant 0.98 isoniazid
kasA 2518795 c.681C>T synonymous_variant 0.98 isoniazid
kasA 2518813 c.699C>T synonymous_variant 1.0 isoniazid
kasA 2518816 c.702C>T synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518843 c.729T>C synonymous_variant 1.0 isoniazid
kasA 2518847 p.Leu245Met missense_variant 1.0 isoniazid
kasA 2518853 p.Leu247Ile missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.97 isoniazid
kasA 2518877 p.Lys255Leu missense_variant 1.0 isoniazid
kasA 2518898 c.784T>C synonymous_variant 1.0 isoniazid
kasA 2518903 c.789C>T synonymous_variant 1.0 isoniazid
kasA 2518906 c.792A>G synonymous_variant 1.0 isoniazid
kasA 2518907 c.793T>C synonymous_variant 1.0 isoniazid
kasA 2518910 p.Leu266Met missense_variant 1.0 isoniazid
kasA 2518936 c.822C>G synonymous_variant 1.0 isoniazid
Rv2477c 2782453 c.1590C>T synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782483 c.1560G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782501 c.1542T>C synonymous_variant 1.0 kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
rifampicin Not assoc w R - Interim
ethambutol
amikacin Not assoc w R - Interim
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782549 c.1494T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
amikacin
Rv2477c 2782555 c.1486_1488delTCGinsAGC synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2782558 c.1485T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783335 c.708C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783344 c.699C>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783386 c.657G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783446 c.597A>G synonymous_variant 1.0 kanamycin
levofloxacin
moxifloxacin
streptomycin
rifampicin
ethambutol
amikacin
Rv2477c 2783456