TB-Profiler result

Run: ERR4798648
Summary

Run ID: ERR4798648

Sample name:

Date: 2024-04-15T18:50:13.107909

Number of reads: 1022798

Percentage reads mapped: 27.16

Median coverage: 17.0

Strain: lineage3.1.2.2

Spoligotype:

Drug-resistance: MDR-TB

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3 East-African-Indian RD750 0.54
lineage3.1.2 East-African-Indian RD750 0.88
lineage3.1.2.2 East-African-Indian RD750 0.14
La1.7.1 M.bovis None 0.11
lineage3.1 East-African-Indian RD750 0.42
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid katG p.Ile335Thr Mutation from literature
c.949_951delATCinsCG Assoc w R High-level resistance
p.Ser315Thr Assoc w R High-level resistance
c.493_495delATTinsCC Assoc w R High-level resistance
ethambutol embB p.Ala356Val Uncertain significance Mutation from literature
p.Tyr384Asn Mutation from literature
p.Gln497Arg Assoc w R
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.166_168delTCCinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC c.532_534delGCAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.799_801delCTAinsTG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.820_822delTTAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.859_861delATCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.895_897delGAAinsCG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.916_918delTTCinsGT Assoc w R - Interim Confers DLM-PMD cross-resistance
c.952_954delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.1195_1197delGTAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.2401_2403delGAAinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiB c.1177_1179delCTGinsGA Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490948 c.166_168delTCCinsGG frameshift_variant&missense_variant 0.85 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 0.8 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.87 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
fbiC 1303462 c.532_534delGCAinsTG frameshift_variant&stop_gained 0.77 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 0.85 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303729 c.799_801delCTAinsTG frameshift_variant&stop_gained 0.91 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303750 c.820_822delTTAinsCG frameshift_variant&missense_variant 0.83 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303789 c.859_861delATCinsGT frameshift_variant&missense_variant 0.86 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303825 c.895_897delGAAinsCG frameshift_variant&missense_variant 0.76 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303846 c.916_918delTTCinsGT frameshift_variant&missense_variant 0.55 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303882 c.952_954delGTTinsAC frameshift_variant&missense_variant 0.6 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1304125 c.1195_1197delGTAinsAC frameshift_variant&missense_variant 0.5 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1305331 c.2401_2403delGAAinsAC frameshift_variant&missense_variant 0.5 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
katG 2155107 p.Ile335Thr missense_variant 0.45 isoniazid Mutation from literature
katG 2155161 c.949_951delATCinsCG frameshift_variant&missense_variant 0.47 isoniazid Assoc w R High-level resistance
katG 2155168 p.Ser315Thr missense_variant 0.52 isoniazid Assoc w R High-level resistance
katG 2155617 c.493_495delATTinsCC frameshift_variant&missense_variant 0.53 isoniazid Assoc w R High-level resistance
fbiB 3642711 c.1177_1179delCTGinsGA frameshift_variant&missense_variant 0.67 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
embB 4247580 p.Ala356Val missense_variant 0.78 ethambutol Uncertain significance Mutation from literature
embB 4247663 p.Tyr384Asn missense_variant 0.55 ethambutol Mutation from literature
embB 4248003 p.Gln497Arg missense_variant 0.35 ethambutol Assoc w R
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 741 c.741T>C synonymous_variant 0.65 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>A synonymous_variant 0.7 isoniazid
dnaA 756 c.756T>C synonymous_variant 0.72 isoniazid
dnaA 771 c.771A>G synonymous_variant 0.75 isoniazid
dnaA 777 c.777A>G synonymous_variant 0.76 isoniazid
dnaA 792 c.792C>T synonymous_variant 0.74 isoniazid
dnaA 795 c.795A>C synonymous_variant 0.74 isoniazid Not assoc w R - Interim
dnaA 805 c.805_807delTTGinsCT frameshift_variant&synonymous_variant 0.75 isoniazid Uncertain significance
dnaA 819 c.819C>T synonymous_variant 0.75 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.75 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.76 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.78 isoniazid
dnaA 840 c.840G>A synonymous_variant 0.77 isoniazid
dnaA 846 c.846T>C synonymous_variant 0.77 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.77 isoniazid
dnaA 852 c.852G>A synonymous_variant 0.77 isoniazid Not assoc w R - Interim
dnaA 876 c.876C>G synonymous_variant 0.84 isoniazid
dnaA 885 c.885T>C synonymous_variant 0.83 isoniazid
dnaA 891 c.891C>T synonymous_variant 0.85 isoniazid Not assoc w R - Interim
dnaA 897 c.897A>G synonymous_variant 0.81 isoniazid
dnaA 903 c.903C>G synonymous_variant 0.81 isoniazid Not assoc w R - Interim
dnaA 909 c.909A>G synonymous_variant 0.81 isoniazid
dnaA 912 c.912T>G synonymous_variant 0.8 isoniazid
dnaA 918 c.918C>G synonymous_variant 0.79 isoniazid
dnaA 921 c.921A>G synonymous_variant 0.8 isoniazid Not assoc w R - Interim
dnaA 936 c.936C>G synonymous_variant 0.76 isoniazid
dnaA 939 c.939C>G synonymous_variant 0.78 isoniazid
dnaA 942 c.942C>G synonymous_variant 0.83 isoniazid
dnaA 945 c.945G>A synonymous_variant 0.83 isoniazid
dnaA 955 c.955A>C synonymous_variant 0.81 isoniazid
dnaA 963 c.963C>G synonymous_variant 0.8 isoniazid
dnaA 966 c.966T>C synonymous_variant 0.8 isoniazid
dnaA 969 c.969G>A synonymous_variant 0.8 isoniazid
dnaA 975 c.975G>C synonymous_variant 0.75 isoniazid
dnaA 976 c.976C>T synonymous_variant 0.83 isoniazid Not assoc w R - Interim
dnaA 984 c.984T>C synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 990 c.990A>C synonymous_variant 0.86 isoniazid
dnaA 996 c.996A>G synonymous_variant 0.87 isoniazid
dnaA 1008 c.1008G>A synonymous_variant 0.86 isoniazid Not assoc w R - Interim
dnaA 1020 c.1020C>G synonymous_variant 0.8 isoniazid
dnaA 1023 c.1023C>T synonymous_variant 0.8 isoniazid
dnaA 1024 c.1024T>C synonymous_variant 0.82 isoniazid
dnaA 1029 c.1029C>T synonymous_variant 0.85 isoniazid
dnaA 1050 c.1050G>C synonymous_variant 0.84 isoniazid
dnaA 1068 c.1068T>C synonymous_variant 0.87 isoniazid
dnaA 1074 c.1074C>G synonymous_variant 0.86 isoniazid
dnaA 1078 c.1078_1080delCTCinsTG frameshift_variant&missense_variant 0.86 isoniazid Uncertain significance
dnaA 1092 c.1092T>C synonymous_variant 0.87 isoniazid Not assoc w R - Interim
dnaA 1095 c.1095C>T synonymous_variant 0.84 isoniazid Not assoc w R - Interim
dnaA 1104 c.1104T>C synonymous_variant 0.85 isoniazid
dnaA 1119 c.1119G>A synonymous_variant 0.83 isoniazid
dnaA 1125 c.1125G>A synonymous_variant 0.82 isoniazid Not assoc w R - Interim
dnaA 1137 c.1137C>T synonymous_variant 0.76 isoniazid Not assoc w R - Interim
dnaA 1140 c.1140C>G synonymous_variant 0.75 isoniazid
dnaA 1149 c.1149C>G synonymous_variant 0.73 isoniazid Not assoc w R - Interim
dnaA 1152 c.1152A>C synonymous_variant 0.73 isoniazid
dnaA 1153 c.1153T>C synonymous_variant 0.73 isoniazid
dnaA 1161 c.1161A>G synonymous_variant 0.79 isoniazid
dnaA 1164 c.1164A>G synonymous_variant 0.76 isoniazid
dnaA 1167 c.1167A>G synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 1173 c.1173C>T synonymous_variant 0.81 isoniazid
dnaA 1177 p.Ala393Ser missense_variant 0.81 isoniazid
dnaA 1180 c.1180C>T synonymous_variant 0.79 isoniazid Not assoc w R - Interim
dnaA 1191 c.1191T>C synonymous_variant 0.8 isoniazid
dnaA 1197 c.1197T>G synonymous_variant 0.8 isoniazid
dnaA 1200 c.1200C>G synonymous_variant 0.78 isoniazid
dnaA 1203 c.1203T>C synonymous_variant 0.76 isoniazid
dnaA 1215 c.1215C>T synonymous_variant 0.72 isoniazid
dnaA 1220 p.Asn407Ser missense_variant 0.73 isoniazid
dnaA 1230 c.1230A>G synonymous_variant 0.69 isoniazid
dnaA 1254 c.1254T>C synonymous_variant 0.68 isoniazid
dnaA 1263 c.1263C>G synonymous_variant 0.62 isoniazid
dnaA 1266 c.1266A>G synonymous_variant 0.6 isoniazid
dnaA 1278 c.1278T>C synonymous_variant 0.59 isoniazid
dnaA 1287 c.1287A>G synonymous_variant 0.57 isoniazid
dnaA 1293 c.1293T>G synonymous_variant 0.55 isoniazid
gyrB 5359 c.120C>G synonymous_variant 0.54 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 5362 c.123T>C synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 5363 c.124_126delTTAinsCG frameshift_variant&missense_variant 0.47 levofloxacin Uncertain significance
moxifloxacin
gyrB 5371 c.132T>C synonymous_variant 0.5 levofloxacin
moxifloxacin
gyrB 6115 c.876A>G synonymous_variant 0.47 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrB 6190 c.951A>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrB 6238 c.999G>A synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.79 levofloxacin
moxifloxacin
gyrB 6253 c.1014G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 0.8 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6280 c.1041T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrB 6299 c.1060C>T synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 0.74 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6316 c.-986G>C upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 6331 c.-971A>G upstream_gene_variant 0.71 levofloxacin
moxifloxacin
gyrA 6700 c.-602T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.79 levofloxacin
moxifloxacin
gyrA 6706 c.-596G>A upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.85 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6733 c.-569G>A upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrA 6769 c.-533C>T upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6787 c.-515G>A upstream_gene_variant 0.73 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 0.69 levofloxacin
moxifloxacin
gyrB 6802 c.1563G>A synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6911 p.Asn558His missense_variant 0.9 levofloxacin
moxifloxacin
gyrB 6931 c.1692A>G synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6934 c.-368A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6949 c.-353A>G upstream_gene_variant 0.88 levofloxacin
moxifloxacin
gyrA 6955 c.-347G>A upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6967 c.-335T>C upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6970 c.-332C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6976 c.-326A>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6982 c.-320A>C upstream_gene_variant 0.86 levofloxacin
moxifloxacin
gyrA 6985 c.-317C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6994 c.-308C>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 6997 c.-305G>A upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7000 c.-302C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7003 c.-299C>T upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7006 c.-296T>G upstream_gene_variant 0.8 levofloxacin
moxifloxacin
gyrA 7007 c.-295C>T upstream_gene_variant 0.75 levofloxacin
moxifloxacin
gyrB 7023 p.Leu595Gln missense_variant 0.78 levofloxacin
moxifloxacin
gyrA 7030 c.-272C>G upstream_gene_variant 0.32 levofloxacin
moxifloxacin
gyrA 7048 c.-254G>A upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrB 7051 p.Glu604Asp missense_variant 0.64 levofloxacin
moxifloxacin
gyrB 7057 c.1818C>T synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7060 c.1821T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7090 c.-212C>T upstream_gene_variant 0.44 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 0.47 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 0.55 levofloxacin
moxifloxacin
gyrA 7129 c.-173T>G upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 0.45 levofloxacin
moxifloxacin
gyrA 7136 c.-166T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7147 c.-155G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7153 c.-149G>T upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrB 7156 c.1917C>T synonymous_variant 0.5 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7174 c.-128C>T upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.47 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.5 levofloxacin
moxifloxacin
gyrA 7201 c.-101G>A upstream_gene_variant 0.53 levofloxacin
moxifloxacin
gyrA 7213 c.-89G>C upstream_gene_variant 0.54 levofloxacin
moxifloxacin
gyrB 7216 c.1977G>C synonymous_variant 0.64 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7225 c.-77T>C upstream_gene_variant 0.64 levofloxacin
moxifloxacin
gyrA 7362 c.61_63delGAGinsCA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7422 c.121C>T synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 0.81 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7469 c.168C>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7472 c.171T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 0.84 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7490 c.189C>G synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7502 c.201C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 7526 c.225G>T synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>C synonymous_variant 0.83 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7601 c.300C>G synonymous_variant 0.86 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7626 c.325C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7643 c.342C>T synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7646 c.345C>T synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7655 c.354G>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 0.85 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7679 c.378G>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7700 c.399G>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 7706 c.405C>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 7725 c.424C>T synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.77 levofloxacin
moxifloxacin
gyrA 7763 c.462T>C synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7769 c.468C>T synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7793 c.492G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 0.76 levofloxacin
moxifloxacin
gyrA 7820 c.519G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 7832 c.531G>T synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 7868 c.567C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 7883 c.582G>C synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 7884 c.583_585delCGTinsGC frameshift_variant&missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 7892 c.591G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7898 p.Asp199Glu missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 7901 c.600G>T synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7904 c.603G>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 7919 p.Glu206Asp missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 7922 c.621T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 7923 p.His208Tyr missense_variant 0.63 levofloxacin
moxifloxacin
gyrA 7940 c.639G>A synonymous_variant 0.61 levofloxacin
moxifloxacin
gyrA 7942 p.Glu214Ala missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 7946 c.645C>G synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7947 c.646C>T synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 7963 p.Gly221Glu missense_variant 0.55 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 0.44 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.54 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.57 levofloxacin
moxifloxacin
gyrA 8189 c.888G>C synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8192 c.891C>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8201 c.900C>G synonymous_variant 0.63 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8207 c.906T>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 0.61 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8222 c.921C>T synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8225 c.924T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8231 c.930C>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8234 c.933T>G synonymous_variant 0.59 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 0.59 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 0.65 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8270 c.969G>C synonymous_variant 0.58 levofloxacin
moxifloxacin
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 0.54 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 0.52 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8324 c.1023T>C synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>G synonymous_variant 0.59 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 0.59 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8360 c.1059G>A synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8372 c.1071G>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 8375 c.1074G>C synonymous_variant 0.67 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 0.67 levofloxacin
moxifloxacin
gyrA 8391 p.Tyr364Leu missense_variant 0.61 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 0.6 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8402 p.Asp367Glu missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8408 c.1107A>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8417 c.1116C>G synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 8420 c.1119T>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8423 c.1122G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8426 c.1125G>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8429 c.1128C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8442 c.1141C>T synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8450 c.1149G>A synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 0.69 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 8480 c.1179C>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 0.66 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8492 c.1191G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8504 c.1203G>C synonymous_variant 0.63 levofloxacin
moxifloxacin
gyrA 8516 c.1215T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 0.62 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 8531 c.1230G>T synonymous_variant 0.69 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8535 p.Glu412Gln missense_variant 0.7 levofloxacin
moxifloxacin
gyrA 8543 c.1242C>T synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 0.75 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8555 c.1254G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 0.81 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8585 c.1284C>T synonymous_variant 0.84 levofloxacin
moxifloxacin
gyrA 8588 c.1287G>A synonymous_variant 0.83 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8642 c.1341A>G synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8655 p.Ile452Val missense_variant 0.9 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8678 c.1377G>A synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 8694 c.1393C>T synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8711 c.1410A>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 8717 c.1416C>G synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8720 c.1419G>A synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 8747 c.1446A>G synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 0.53 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8840 c.1539C>G synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 0.65 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 0.68 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 0.7 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>T synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 8888 c.1587C>G synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.85 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>G synonymous_variant 0.82 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 8933 c.1632G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8936 c.1635G>A synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.82 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.84 levofloxacin
moxifloxacin
gyrA 8983 p.Cys561Ser missense_variant 0.87 levofloxacin
moxifloxacin
gyrA 8987 c.1686C>G synonymous_variant 0.88 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>G synonymous_variant 0.89 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 0.86 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9003 c.1702C>T synonymous_variant 0.86 levofloxacin
moxifloxacin
gyrA 9023 c.1722A>C synonymous_variant 0.84 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9029 c.1728T>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9032 c.1731T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9035 c.1734G>C synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9038 c.1737C>G synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9050 p.Asp583Glu missense_variant 0.62 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9051 c.1750T>C synonymous_variant 0.62 levofloxacin
moxifloxacin
gyrA 9062 c.1761C>A synonymous_variant 0.64 levofloxacin
moxifloxacin
gyrA 9071 c.1770G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9074 c.1773G>C synonymous_variant 0.68 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>T synonymous_variant 0.72 levofloxacin
moxifloxacin
gyrA 9089 c.1788G>C synonymous_variant 0.74 levofloxacin
moxifloxacin
gyrA 9101 c.1800A>G synonymous_variant 0.73 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9104 c.1803C>A synonymous_variant 0.73 levofloxacin
moxifloxacin
gyrA 9110 c.1809G>A synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9128 c.1827C>A synonymous_variant 0.76 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9143 c.1842T>C synonymous_variant 0.69 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9147 p.Gly616Ser missense_variant 0.74 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 0.71 levofloxacin
moxifloxacin
gyrA 9161 c.1860C>G synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9164 c.1863G>C synonymous_variant 0.71 levofloxacin
moxifloxacin
gyrA 9167 c.1866C>T synonymous_variant 0.67 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 0.71 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9183 p.Arg628Lys missense_variant 0.69 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9230 c.1929T>C synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 0.77 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9252 p.Val651Ile missense_variant 0.79 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9266 c.1965C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 0.75 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 0.76 levofloxacin
moxifloxacin
gyrA 9291 c.1990C>T synonymous_variant 0.78 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 0.78 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9308 p.Asp669Glu missense_variant 0.79 levofloxacin
moxifloxacin
gyrA 9315 c.2014C>T synonymous_variant 0.79 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9326 c.2025G>T synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9338 c.2037G>A synonymous_variant 0.8 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 0.79 levofloxacin
moxifloxacin
gyrA 9383 c.2082T>C synonymous_variant 0.7 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>C synonymous_variant 0.65 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9395 c.2094G>C synonymous_variant 0.55 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9398 c.2097T>C synonymous_variant 0.56 levofloxacin
moxifloxacin
fgd1 490851 c.69A>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 490854 c.72C>G synonymous_variant 0.48 clofazimine
pretomanid
delamanid
fgd1 490857 c.75C>G synonymous_variant 0.5 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>A synonymous_variant 0.63 clofazimine
pretomanid
delamanid
fgd1 490887 c.105G>C synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 490890 c.108C>G synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fgd1 490899 c.117C>T synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fgd1 490921 p.Gln47Glu missense_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 490929 c.147C>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 490932 c.150T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 490971 c.189A>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490980 p.Asn66Lys missense_variant 0.85 clofazimine
pretomanid
delamanid
fgd1 490983 c.201G>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 490988 p.Leu69Gln missense_variant 0.87 clofazimine
pretomanid
delamanid
fgd1 490995 c.213C>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491007 c.225G>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491040 c.258C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491052 c.270C>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491058 c.276C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>C synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 0.8 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491070 c.288G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491077 p.Asn99Asp missense_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491082 c.300T>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491097 c.315G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491109 c.327G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fgd1 491110 p.Ala110Ser missense_variant 0.8 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491136 c.354C>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fgd1 491144 p.Ala121Glu missense_variant 0.81 clofazimine
pretomanid
delamanid
fgd1 491166 c.384G>T synonymous_variant 0.74 clofazimine
pretomanid
delamanid
fgd1 491168 p.Phe129Tyr missense_variant 0.67 clofazimine
pretomanid
delamanid
fgd1 491175 c.393G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491178 c.396G>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>C synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 0.6 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Leu missense_variant 0.57 clofazimine
pretomanid
delamanid
fgd1 491223 c.441C>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 0.56 clofazimine
pretomanid
delamanid
mshA 574607 c.-741G>A upstream_gene_variant 0.42 ethionamide
isoniazid
mshA 574610 c.-738G>A upstream_gene_variant 0.44 ethionamide
isoniazid
mshA 574616 c.-732G>C upstream_gene_variant 0.5 ethionamide
isoniazid
mshA 574640 c.-708G>A upstream_gene_variant 0.62 ethionamide
isoniazid
mshA 574646 c.-702G>A upstream_gene_variant 0.62 ethionamide
isoniazid
mshA 574650 c.-698A>C upstream_gene_variant 0.62 ethionamide
isoniazid
mshA 574667 c.-681G>A upstream_gene_variant 0.61 ethionamide
isoniazid
mshA 574673 c.-675A>G upstream_gene_variant 0.59 ethionamide
isoniazid
mshA 574676 c.-672G>C upstream_gene_variant 0.59 ethionamide
isoniazid
mshA 574683 c.-665T>C upstream_gene_variant 0.59 ethionamide
isoniazid Uncertain significance
mshA 574688 c.-660G>C upstream_gene_variant 0.54 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 574694 c.-654C>G upstream_gene_variant 0.55 ethionamide
isoniazid
mshA 574712 c.-636A>G upstream_gene_variant 0.53 ethionamide
isoniazid
mshA 574718 c.-630A>G upstream_gene_variant 0.5 ethionamide
isoniazid
mshA 574721 c.-627C>A upstream_gene_variant 0.5 ethionamide
isoniazid
mshA 574724 c.-624T>C upstream_gene_variant 0.52 ethionamide
isoniazid
mshA 574727 c.-621G>C upstream_gene_variant 0.52 ethionamide
isoniazid
mshA 574731 c.-617A>G upstream_gene_variant 0.56 ethionamide
isoniazid
mshA 574739 c.-609T>C upstream_gene_variant 0.56 ethionamide
isoniazid
mshA 575009 c.-339T>C upstream_gene_variant 0.43 ethionamide
isoniazid
mshA 575011 c.-337G>A upstream_gene_variant 0.47 ethionamide
isoniazid
mshA 575022 c.-326C>T upstream_gene_variant 0.53 ethionamide
isoniazid
mshA 575034 c.-314_-312delTTAinsCG upstream_gene_variant 0.6 ethionamide
isoniazid
mshA 575042 c.-306T>C upstream_gene_variant 0.68 ethionamide
isoniazid
mshA 575051 c.-297A>G upstream_gene_variant 0.68 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575052 c.-296G>C upstream_gene_variant 0.68 ethionamide
isoniazid
mshA 575072 c.-276G>C upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 575075 c.-273T>C upstream_gene_variant 0.77 ethionamide
isoniazid Uncertain significance
mshA 575081 c.-267A>G upstream_gene_variant 0.77 ethionamide
isoniazid
mshA 575087 c.-261C>G upstream_gene_variant 0.8 ethionamide
isoniazid
mshA 575109 c.-239G>T upstream_gene_variant 0.82 ethionamide
isoniazid
mshA 575114 c.-234G>A upstream_gene_variant 0.79 ethionamide
isoniazid Uncertain significance
mshA 575117 c.-231T>C upstream_gene_variant 0.79 ethionamide
isoniazid
mshA 575118 c.-230A>G upstream_gene_variant 0.79 ethionamide
isoniazid Uncertain significance
mshA 575123 c.-225A>G upstream_gene_variant 0.79 ethionamide
isoniazid
mshA 575124 c.-224_-222delGGGinsCT upstream_gene_variant 0.79 ethionamide
isoniazid
mshA 575144 c.-204T>G upstream_gene_variant 0.79 ethionamide
isoniazid
mshA 575153 c.-195C>A upstream_gene_variant 0.83 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575161 c.-187_-186delTTinsCC upstream_gene_variant 0.81 ethionamide
isoniazid
mshA 575192 c.-156A>C upstream_gene_variant 0.64 ethionamide
isoniazid
mshA 575575 c.228G>A synonymous_variant 0.71 ethionamide
isoniazid
mshA 575576 c.229C>T synonymous_variant 0.71 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575588 c.241_243delCGTinsAG frameshift_variant&missense_variant 0.75 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575596 c.249C>T synonymous_variant 0.75 ethionamide
isoniazid
mshA 575605 c.258G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575608 c.261G>A synonymous_variant 0.79 ethionamide
isoniazid Not assoc w R - Interim
mshA 575620 c.273G>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575629 c.282A>C synonymous_variant 0.75 ethionamide
isoniazid
mshA 575635 c.288A>C synonymous_variant 0.79 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575641 c.294A>G synonymous_variant 0.79 ethionamide
isoniazid
mshA 575647 c.300G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575649 c.302_303insA frameshift_variant 0.79 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575654 p.Val103Leu missense_variant 0.75 ethionamide
isoniazid
mshA 575665 c.318G>C synonymous_variant 0.78 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575695 c.348C>G synonymous_variant 0.82 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 0.85 ethionamide
isoniazid
mshA 575705 c.358T>C synonymous_variant 0.85 ethionamide
isoniazid
mshA 575713 c.366G>A synonymous_variant 0.82 ethionamide
isoniazid
mshA 575719 c.372C>T synonymous_variant 0.8 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575734 c.387T>G synonymous_variant 0.83 ethionamide
isoniazid
mshA 575746 c.399C>G synonymous_variant 0.81 ethionamide
isoniazid
mshA 575767 c.420G>A synonymous_variant 0.81 ethionamide
isoniazid
mshA 575771 p.Val142Ser missense_variant 0.81 ethionamide
isoniazid
mshA 575779 p.Glu144Asp missense_variant 0.81 ethionamide
isoniazid
mshA 575780 c.433_435delCCGinsGC frameshift_variant&missense_variant 0.81 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575821 c.474G>C synonymous_variant 0.78 ethionamide
isoniazid
mshA 575824 c.477T>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.8 ethionamide
isoniazid
mshA 575845 c.498C>G synonymous_variant 0.82 ethionamide
isoniazid
mshA 575848 c.501C>T synonymous_variant 0.82 ethionamide
isoniazid
mshA 575851 c.504C>G synonymous_variant 0.83 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.82 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 0.79 ethionamide
isoniazid
mshA 575887 c.540G>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 575890 c.543C>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 0.8 ethionamide
isoniazid
mshA 575899 c.552G>A synonymous_variant 0.8 ethionamide
isoniazid
mshA 575916 p.Asp190Val missense_variant 0.83 ethionamide
isoniazid
mshA 575924 p.Gly193Ser missense_variant 0.8 ethionamide
isoniazid
mshA 575935 c.588G>T synonymous_variant 0.79 ethionamide
isoniazid
mshA 575944 c.597T>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 575945 p.Thr200Ala missense_variant 0.74 ethionamide
isoniazid
mshA 575950 c.603C>G synonymous_variant 0.72 ethionamide
isoniazid
mshA 575953 c.606G>T synonymous_variant 0.73 ethionamide
isoniazid
mshA 575965 c.618C>G synonymous_variant 0.73 ethionamide
isoniazid Not assoc w R - Interim
mshA 575968 c.621C>G synonymous_variant 0.71 ethionamide
isoniazid
ccsA 619507 c.-384A>G upstream_gene_variant 0.57 capreomycin
amikacin
kanamycin
ccsA 619516 c.-375C>G upstream_gene_variant 0.45 capreomycin
amikacin
kanamycin
ccsA 619525 c.-366C>T upstream_gene_variant 0.45 capreomycin
amikacin
kanamycin
ccsA 619531 c.-360T>C upstream_gene_variant 0.45 capreomycin
amikacin
kanamycin
ccsA 619534 c.-357G>A upstream_gene_variant 0.45 capreomycin
amikacin
kanamycin
ccsA 619537 c.-354A>G upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619540 c.-351C>G upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619543 c.-348C>G upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619544 c.-347A>C upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619552 c.-339A>G upstream_gene_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 619555 c.-336C>T upstream_gene_variant 0.41 capreomycin
amikacin
kanamycin
ccsA 619561 c.-330G>C upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619564 c.-327C>G upstream_gene_variant 0.4 capreomycin
amikacin
kanamycin
ccsA 619570 c.-321G>C upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619573 c.-318G>C upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619574 c.-317G>A upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619579 c.-312G>C upstream_gene_variant 0.43 capreomycin
amikacin
kanamycin
ccsA 619588 c.-303C>G upstream_gene_variant 0.47 capreomycin
amikacin
kanamycin
ccsA 619591 c.-300G>C upstream_gene_variant 0.47 capreomycin
amikacin
kanamycin
ccsA 619594 c.-297G>A upstream_gene_variant 0.47 capreomycin
amikacin
kanamycin
ccsA 619624 c.-267C>T upstream_gene_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620238 c.348G>C synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.72 capreomycin
amikacin
kanamycin
ccsA 620249 p.Ser120Cys missense_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620253 c.363G>C synonymous_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620254 c.364_366delCTCinsTG frameshift_variant&missense_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.71 capreomycin
amikacin
kanamycin
ccsA 620284 c.394_396delGCGinsCA frameshift_variant&missense_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620291 p.Tyr134Phe missense_variant 0.67 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.6 capreomycin
amikacin
kanamycin
ccsA 620317 c.427_429delGTCinsCG frameshift_variant&missense_variant 0.58 capreomycin
amikacin
kanamycin
ccsA 620325 c.435G>C synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620343 c.453G>C synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>T synonymous_variant 0.58 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.58 capreomycin
amikacin
kanamycin
ccsA 620367 c.477T>C synonymous_variant 0.5 capreomycin
amikacin
kanamycin
ccsA 620373 c.483C>G synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620376 c.486G>C synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620388 c.498A>C synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620389 c.499C>T synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620394 c.504G>A synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620400 c.510C>T synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620412 c.522T>C synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620415 c.525T>C synonymous_variant 0.46 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620418 c.528G>C synonymous_variant 0.46 capreomycin
amikacin
kanamycin
ccsA 620430 c.540C>T synonymous_variant 0.35 capreomycin
amikacin
kanamycin
ccsA 620433 c.543C>G synonymous_variant 0.36 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620436 c.546T>C synonymous_variant 0.36 capreomycin
amikacin
kanamycin
ccsA 620439 c.549T>C synonymous_variant 0.4 capreomycin
amikacin
kanamycin
ccsA 620442 c.552G>C synonymous_variant 0.38 capreomycin
amikacin
kanamycin
ccsA 620445 c.555A>C synonymous_variant 0.44 capreomycin
amikacin
kanamycin
ccsA 620448 c.558C>T synonymous_variant 0.42 capreomycin
amikacin
kanamycin
ccsA 620598 c.708C>G synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 0.48 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 0.52 capreomycin
amikacin
kanamycin
ccsA 620613 c.723C>G synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 0.58 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 0.64 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 0.63 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 0.61 capreomycin
amikacin
kanamycin
ccsA 620661 c.771C>G synonymous_variant 0.66 capreomycin
amikacin
kanamycin
ccsA 620685 c.795G>A synonymous_variant 0.74 capreomycin Not assoc w R - Interim
amikacin
kanamycin Not assoc w R - Interim
ccsA 620698 p.Val270Ile missense_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 0.78 capreomycin
amikacin
kanamycin
ccsA 620715 c.825C>T synonymous_variant 0.79 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>A synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620742 c.852G>C synonymous_variant 0.8 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>C synonymous_variant 0.81 capreomycin
amikacin
kanamycin
ccsA 620778 c.888T>C synonymous_variant 0.75 capreomycin
amikacin
kanamycin
ccsA 620781 c.891C>G synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620783 p.Ala298Val missense_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620787 c.897C>A synonymous_variant 0.69 capreomycin
amikacin
kanamycin
ccsA 620796 c.906C>G synonymous_variant 0.7 capreomycin
amikacin
kanamycin
ccsA 620829 c.939G>C synonymous_variant 0.62 capreomycin
amikacin
kanamycin
ccsA 620835 c.945C>G synonymous_variant 0.58 capreomycin
amikacin
kanamycin
ccsA 620844 c.954C>T synonymous_variant 0.54 capreomycin
amikacin
kanamycin
ccsA 620853 c.963G>C synonymous_variant 0.48 capreomycin Not assoc w R - Interim
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
Rv0565c 657183 c.288G>A synonymous_variant 0.68 ethionamide
Rv0565c 657189 c.282C>A synonymous_variant 0.68 ethionamide
Rv0565c 657193 p.Met93Thr missense_variant 0.68 ethionamide
Rv0565c 657196 p.Asp92Ala missense_variant 0.68 ethionamide
Rv0565c 657200 p.Thr91Ala missense_variant 0.68 ethionamide Uncertain significance
Rv0565c 657210 c.261C>T synonymous_variant 0.67 ethionamide Not assoc w R - Interim
Rv0565c 657213 c.258C>T synonymous_variant 0.64 ethionamide
Rv0565c 657219 p.Ala84Val missense_variant 0.67 ethionamide
Rv0565c 657233 p.Ile80Val missense_variant 0.72 ethionamide
Rv0565c 657240 c.229_231delGAAinsAG frameshift_variant&synonymous_variant 0.72 ethionamide Uncertain significance
Rv0565c 657252 c.219G>C synonymous_variant 0.74 ethionamide
Rv0565c 657255 c.216G>A synonymous_variant 0.74 ethionamide
Rv0565c 657259 p.Tyr71Phe missense_variant 0.74 ethionamide
Rv0565c 657294 c.177C>A synonymous_variant 0.75 ethionamide
Rv0565c 657306 c.165C>T synonymous_variant 0.69 ethionamide
Rv0565c 657312 c.159C>T synonymous_variant 0.62 ethionamide
Rv0565c 657318 c.153T>C synonymous_variant 0.62 ethionamide
Rv0565c 657324 c.147C>G synonymous_variant 0.59 ethionamide
Rv0565c 657668 c.-198C>T upstream_gene_variant 0.82 ethionamide
Rv0565c 657678 c.-208A>C upstream_gene_variant 0.87 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 0.83 ethionamide
Rv0565c 657695 c.-225C>G upstream_gene_variant 0.86 ethionamide
Rv0565c 657725 c.-255G>A upstream_gene_variant 0.96 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 0.96 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 0.92 ethionamide
hadA 731686 c.-244_-243insATGT upstream_gene_variant 0.6 isoniazid
hadA 731689 c.-240_-237delAGAC upstream_gene_variant 0.6 isoniazid
hadA 731695 c.-235C>T upstream_gene_variant 0.6 isoniazid
hadA 731698 c.-232T>G upstream_gene_variant 0.65 isoniazid
hadA 731708 c.-222G>A upstream_gene_variant 0.68 isoniazid
hadA 731711 c.-219T>C upstream_gene_variant 0.68 isoniazid
hadA 731726 c.-204C>G upstream_gene_variant 0.75 isoniazid
hadA 731729 c.-201C>T upstream_gene_variant 0.75 isoniazid
hadA 731753 c.-177A>C upstream_gene_variant 0.78 isoniazid
hadA 731756 c.-174C>T upstream_gene_variant 0.77 isoniazid
hadA 731774 c.-156T>C upstream_gene_variant 0.75 isoniazid
hadA 731786 c.-144C>G upstream_gene_variant 0.75 isoniazid
hadA 731789 c.-141A>G upstream_gene_variant 0.75 isoniazid
hadA 731807 c.-123C>T upstream_gene_variant 0.71 isoniazid
hadA 731819 c.-111G>C upstream_gene_variant 0.7 isoniazid
hadA 731843 c.-87T>C upstream_gene_variant 0.76 isoniazid
hadA 731852 c.-78A>G upstream_gene_variant 0.67 isoniazid
hadA 732305 c.376_378delATCinsGG frameshift_variant&missense_variant 0.67 isoniazid Uncertain significance
hadA 732308 p.Val127Ile missense_variant 0.67 isoniazid
hadA 732314 p.Asn129Asp missense_variant 0.67 isoniazid
hadA 732319 c.390G>A synonymous_variant 0.67 isoniazid
hadA 732321 p.Glu131Ala missense_variant 0.67 isoniazid
hadA 732329 p.Leu134Ile missense_variant 0.69 isoniazid
hadA 732346 c.417T>C synonymous_variant 0.72 isoniazid
hadA 732378 c.450_452dupAGA disruptive_inframe_insertion 0.77 isoniazid
hadA 732396 p.Gly156Ala missense_variant 0.79 isoniazid
hadA 732398 p.Ala157Thr missense_variant 0.79 isoniazid
nusG 734120 c.-134T>C upstream_gene_variant 0.43 rifampicin Uncertain significance
nusG 734129 c.-125G>C upstream_gene_variant 0.56 rifampicin
nusG 734142 c.-112_-110delGCGinsATA upstream_gene_variant 0.67 rifampicin
nusG 734147 c.-107T>C upstream_gene_variant 0.62 rifampicin
nusG 734150 c.-104G>C upstream_gene_variant 0.62 rifampicin
nusG 734153 c.-101C>A upstream_gene_variant 0.7 rifampicin
nusG 734171 c.-83_-82insG upstream_gene_variant 0.67 rifampicin
nusG 734175 c.-79G>T upstream_gene_variant 0.67 rifampicin
nusG 734177 c.-76delG upstream_gene_variant 0.67 rifampicin
nusG 734183 c.-71C>T upstream_gene_variant 0.67 rifampicin
nusG 734186 c.-68G>C upstream_gene_variant 0.67 rifampicin Uncertain significance
nusG 734203 c.-51_-50delTGinsCC upstream_gene_variant 0.67 rifampicin
nusG 734205 c.-49A>C upstream_gene_variant 0.67 rifampicin
nusG 734208 c.-46T>C upstream_gene_variant 0.67 rifampicin
nusG 734403 c.150C>T synonymous_variant 0.71 rifampicin
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 0.7 rifampicin
nusG 734421 c.168A>C synonymous_variant 0.79 rifampicin
nusG 734424 c.171G>C synonymous_variant 0.77 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.8 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.83 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.83 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734478 c.225C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.85 rifampicin
nusG 734520 c.267C>A synonymous_variant 0.91 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.86 rifampicin
rpoB 760056 c.250_252delCTCinsTG frameshift_variant&missense_variant 0.64 rifampicin
rpoB 760070 c.264T>G synonymous_variant 0.68 rifampicin
rpoB 760091 c.285G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760101 c.295T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 760109 c.303C>T synonymous_variant 0.71 rifampicin
rpoB 760112 c.306T>C synonymous_variant 0.72 rifampicin
rpoB 760118 c.312T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760121 c.315T>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 760130 p.Asp108Glu missense_variant 0.74 rifampicin Uncertain significance
rpoB 760139 c.333A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoB 760142 c.336C>G synonymous_variant 0.73 rifampicin
rpoB 760145 c.339C>G synonymous_variant 0.74 rifampicin
rpoB 760181 c.375T>A synonymous_variant 0.78 rifampicin
rpoB 760184 c.378A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760235 c.429T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 0.81 rifampicin
rpoB 760295 c.489C>T synonymous_variant 0.85 rifampicin
rpoB 760307 c.501T>C synonymous_variant 0.84 rifampicin
rpoB 760310 c.504G>C synonymous_variant 0.85 rifampicin
rpoB 760328 c.522G>C synonymous_variant 0.85 rifampicin
rpoB 760331 c.525G>C synonymous_variant 0.85 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.84 rifampicin
rpoB 760340 c.534G>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 760358 c.552C>G synonymous_variant 0.82 rifampicin
rpoB 760361 c.555T>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.81 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 0.82 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.81 rifampicin
rpoB 760403 c.597C>T synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 760412 c.606C>T synonymous_variant 0.79 rifampicin
rpoB 760414 p.Gly203Asp missense_variant 0.79 rifampicin
rpoB 760418 c.612G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 760424 c.618C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760472 c.666C>T synonymous_variant 0.86 rifampicin
rpoB 760475 c.669A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 0.87 rifampicin
rpoB 760484 c.678A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 760493 c.687C>G synonymous_variant 0.91 rifampicin
rpoB 760520 c.714C>G synonymous_variant 0.92 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 0.96 rifampicin Uncertain significance
rpoB 760526 c.720G>A synonymous_variant 0.96 rifampicin
rpoB 760532 c.726T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 0.95 rifampicin
rpoB 760547 c.741G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.96 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.93 rifampicin
rpoB 760601 c.795C>T synonymous_variant 0.94 rifampicin
rpoB 760611 c.805T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 760622 c.816C>T synonymous_variant 0.93 rifampicin
rpoB 760646 c.840C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 760649 c.843G>C synonymous_variant 0.91 rifampicin
rpoB 760655 c.849A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 0.9 rifampicin
rpoB 760674 c.868T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoB 760748 c.942C>G synonymous_variant 0.72 rifampicin
rpoB 760757 c.951T>C synonymous_variant 0.72 rifampicin
rpoB 760759 p.Val318Ala missense_variant 0.72 rifampicin
rpoB 760769 c.963C>G synonymous_variant 0.73 rifampicin
rpoB 760793 c.987A>G synonymous_variant 0.75 rifampicin
rpoB 760805 c.999G>C synonymous_variant 0.78 rifampicin
rpoB 760817 c.1011A>G synonymous_variant 0.67 rifampicin
rpoB 760820 c.1014T>C synonymous_variant 0.65 rifampicin
rpoB 760826 c.1020C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760830 c.1024T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760841 c.1035T>C synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoB 760845 c.1039_1041delACCinsCG frameshift_variant&missense_variant 0.64 rifampicin
rpoB 760856 c.1050C>G synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>G synonymous_variant 0.8 rifampicin
rpoB 760919 c.1113C>G synonymous_variant 0.8 rifampicin
rpoB 760925 c.1119T>C synonymous_variant 0.8 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoB 760931 c.1125C>G synonymous_variant 0.77 rifampicin
rpoB 760937 c.1131G>A synonymous_variant 0.79 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 0.88 rifampicin
rpoB 760982 c.1176G>T synonymous_variant 0.88 rifampicin
rpoB 760985 c.1179G>T synonymous_variant 0.88 rifampicin
rpoB 760991 c.1185G>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>T synonymous_variant 0.87 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.88 rifampicin
rpoB 761027 c.1221A>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.89 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.89 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.89 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761168 c.1362C>G synonymous_variant 0.91 rifampicin
rpoB 761180 c.1374A>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>G synonymous_variant 0.9 rifampicin
rpoB 761192 c.1386C>G synonymous_variant 0.88 rifampicin
rpoB 761195 c.1389G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761240 c.1434C>T synonymous_variant 0.84 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>C synonymous_variant 0.83 rifampicin
rpoB 761261 c.1455G>T synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 0.85 rifampicin
rpoB 761327 c.1521A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>T synonymous_variant 0.84 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 0.85 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 0.83 rifampicin
rpoB 761374 p.Val523Glu missense_variant 0.82 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.87 rifampicin
rpoB 761432 c.1626C>T synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 761435 c.1629T>C synonymous_variant 0.86 rifampicin
rpoB 761438 c.1632G>C synonymous_variant 0.86 rifampicin
rpoB 761444 c.1638T>C synonymous_variant 0.82 rifampicin
rpoB 761452 p.Val549Glu missense_variant 0.81 rifampicin
rpoB 761457 p.Pro551Ser missense_variant 0.81 rifampicin
rpoB 761465 c.1659G>A synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoB 761471 c.1665C>T synonymous_variant 0.81 rifampicin
rpoB 761477 c.1671C>T synonymous_variant 0.83 rifampicin
rpoB 761492 c.1686G>C synonymous_variant 0.81 rifampicin
rpoB 761504 c.1698C>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoB 761510 c.1704T>C synonymous_variant 0.87 rifampicin
rpoB 761531 c.1725C>G synonymous_variant 0.86 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.88 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>A synonymous_variant 0.9 rifampicin
rpoB 761648 c.1842T>C synonymous_variant 0.88 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 0.91 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.9 rifampicin
rpoB 761723 c.1917_1919delAGAinsC frameshift_variant&missense_variant 0.9 rifampicin
rpoB 761732 c.1926C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.89 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 0.91 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.88 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.87 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.88 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.88 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.89 rifampicin
rpoB 761828 c.2022C>T synonymous_variant 0.87 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.88 rifampicin
rpoB 761837 c.2031C>T synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 761848 p.Cys681Ser missense_variant 0.86 rifampicin
rpoB 761852 c.2046C>G synonymous_variant 0.86 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.85 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 0.87 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.89 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 0.89 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 0.87 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 0.87 rifampicin
rpoB 761913 c.2107_2109delGACinsCA frameshift_variant&missense_variant 0.87 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 0.87 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.88 rifampicin
rpoB 761930 c.2124G>C synonymous_variant 0.89 rifampicin
rpoB 761954 c.2148C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762008 c.2202C>G synonymous_variant 0.88 rifampicin
rpoB 762014 c.2208C>T synonymous_variant 0.86 rifampicin
rpoB 762047 c.2241G>A synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.87 rifampicin Uncertain significance
rpoB 762131 c.2325C>G synonymous_variant 0.86 rifampicin
rpoB 762134 c.2328C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 762143 c.2337T>C synonymous_variant 0.87 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 762233 c.2427G>T synonymous_variant 0.93 rifampicin
rpoB 762254 c.2448T>G synonymous_variant 0.92 rifampicin
rpoB 762257 c.2451C>G synonymous_variant 0.92 rifampicin
rpoB 762266 c.2460T>C synonymous_variant 0.93 rifampicin
rpoB 762281 c.2475G>A synonymous_variant 0.94 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 0.89 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 0.88 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.89 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 0.89 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 0.91 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 0.87 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 0.86 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 0.86 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 0.87 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762431 c.2625C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.85 rifampicin
rpoB 762510 c.2704_2706delGCCinsCG frameshift_variant&missense_variant 0.85 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.82 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.82 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.82 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.81 rifampicin
rpoC 762563 c.-807G>A upstream_gene_variant 0.74 rifampicin
rpoB 762827 c.3021G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoB 762833 c.3027C>T synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoB 762857 c.3051C>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoB 762860 c.3054G>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 762902 c.-468C>T upstream_gene_variant 0.79 rifampicin
rpoC 762917 c.-453C>T upstream_gene_variant 0.8 rifampicin
rpoB 762929 c.3123G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>G upstream_gene_variant 0.91 rifampicin
rpoB 762995 c.3189G>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>C synonymous_variant 1.0 rifampicin Not assoc w R
rpoB 763034 c.3228C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.96 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 763082 c.3276C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoB 763166 c.3360A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 0.78 rifampicin
rpoC 763202 c.-168A>C upstream_gene_variant 0.74 rifampicin
rpoC 763205 c.-165G>T upstream_gene_variant 0.73 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.73 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.74 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 763241 c.-129G>A upstream_gene_variant 0.71 rifampicin
rpoC 763250 c.-120C>T upstream_gene_variant 0.73 rifampicin
rpoC 763253 c.-117G>T upstream_gene_variant 0.72 rifampicin
rpoC 763262 c.-108C>A upstream_gene_variant 0.69 rifampicin
rpoC 763265 c.-105G>A upstream_gene_variant 0.69 rifampicin
rpoC 763402 c.33C>T synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763409 c.40_42delCTTinsTG frameshift_variant&missense_variant 0.5 rifampicin
rpoC 763414 c.45T>G synonymous_variant 0.5 rifampicin Not assoc w R - Interim
rpoC 763441 c.72C>T synonymous_variant 0.7 rifampicin
rpoC 763444 c.75T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.84 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763618 c.249C>T synonymous_variant 0.96 rifampicin
rpoC 763636 c.267T>C synonymous_variant 0.96 rifampicin
rpoC 763660 c.291T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763669 c.300C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763703 c.334_336delTCGinsAGC synonymous_variant 0.94 rifampicin
rpoC 763709 c.340C>T synonymous_variant 0.94 rifampicin
rpoC 763714 c.345G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763726 c.357C>T synonymous_variant 0.93 rifampicin
rpoC 763732 c.363C>G synonymous_variant 0.92 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.92 rifampicin
rpoC 763744 c.375G>C synonymous_variant 0.92 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 763771 c.402C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 763780 c.411C>G synonymous_variant 0.89 rifampicin
rpoC 763792 p.Glu141Asp missense_variant 0.87 rifampicin
rpoC 763801 c.432C>G synonymous_variant 0.88 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 0.88 rifampicin
rpoC 763851 p.Ala161Gly missense_variant 0.84 rifampicin
rpoC 763855 c.486C>T synonymous_variant 0.82 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.83 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.82 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 0.81 rifampicin
rpoC 763879 c.510A>G synonymous_variant 0.81 rifampicin
rpoC 763888 c.519G>C synonymous_variant 0.81 rifampicin
rpoC 763891 c.522G>C synonymous_variant 0.78 rifampicin
rpoC 763894 c.525A>G synonymous_variant 0.8 rifampicin
rpoC 763936 c.567C>G synonymous_variant 0.78 rifampicin
rpoC 763939 c.570G>A synonymous_variant 0.8 rifampicin
rpoC 763951 c.582G>A synonymous_variant 0.83 rifampicin
rpoC 763963 c.594C>G synonymous_variant 0.84 rifampicin
rpoC 763967 p.Gly200Ser missense_variant 0.84 rifampicin
rpoC 763972 c.603C>T synonymous_variant 0.85 rifampicin
rpoC 763987 c.618C>T synonymous_variant 0.85 rifampicin
rpoC 763996 c.627T>C synonymous_variant 0.87 rifampicin
rpoC 764005 c.636G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 0.91 rifampicin
rpoC 764024 c.655T>C synonymous_variant 0.94 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.89 rifampicin
rpoC 764044 c.675T>G synonymous_variant 0.88 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.89 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.88 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764101 c.732C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764140 c.771C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764159 c.790C>T synonymous_variant 0.88 rifampicin
rpoC 764167 c.798G>A synonymous_variant 0.87 rifampicin
rpoC 764188 c.819A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764195 p.Ser276Ile missense_variant 0.89 rifampicin
rpoC 764215 c.846A>C synonymous_variant 0.88 rifampicin
rpoC 764218 c.849C>T synonymous_variant 0.87 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>A synonymous_variant 0.87 rifampicin
rpoC 764246 c.877_879delCTCinsTG frameshift_variant&missense_variant 0.87 rifampicin
rpoC 764263 c.894G>C synonymous_variant 0.82 rifampicin
rpoC 764266 c.897T>C synonymous_variant 0.83 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764317 c.948C>G synonymous_variant 0.77 rifampicin
rpoC 764320 c.951C>G synonymous_variant 0.77 rifampicin
rpoC 764365 c.996C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 0.79 rifampicin
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.79 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.75 rifampicin
rpoC 764428 c.1059G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.78 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 0.78 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 0.77 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.82 rifampicin Not assoc w R - Interim
rpoC 764497 c.1128A>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 764503 c.1134G>C synonymous_variant 0.88 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764554 c.1185C>T synonymous_variant 0.82 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.83 rifampicin
rpoC 764593 c.1224C>T synonymous_variant 0.81 rifampicin
rpoC 764605 c.1236G>A synonymous_variant 0.81 rifampicin
rpoC 764626 c.1257C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764668 c.1299C>T synonymous_variant 0.8 rifampicin Not assoc w R - Interim
rpoC 764686 c.1317C>T synonymous_variant 0.81 rifampicin
rpoC 764752 c.1383G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764782 c.1413C>T synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.74 rifampicin
rpoC 764803 c.1434C>G synonymous_variant 0.75 rifampicin
rpoC 764809 c.1440C>T synonymous_variant 0.74 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 764887 c.1518G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.78 rifampicin
rpoC 764896 c.1527C>T synonymous_variant 0.79 rifampicin
rpoC 764902 c.1533C>T synonymous_variant 0.79 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 0.79 rifampicin
rpoC 764923 c.1554A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 764932 c.1563C>G synonymous_variant 0.77 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765007 c.1638T>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.71 rifampicin Not assoc w R - Interim
rpoC 765013 c.1644C>T synonymous_variant 0.7 rifampicin Not assoc w R - Interim
rpoC 765019 c.1650A>G synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.68 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.67 rifampicin Not assoc w R - Interim
rpoC 765053 c.1684_1686delTCCinsAGT synonymous_variant 0.67 rifampicin
rpoC 765065 c.1696C>T synonymous_variant 0.63 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 0.63 rifampicin
rpoC 765079 c.1710T>C synonymous_variant 0.63 rifampicin
rpoC 765082 c.1713G>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765089 c.1720T>C synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>A synonymous_variant 0.63 rifampicin Not assoc w R - Interim
rpoC 765121 c.1752G>T synonymous_variant 0.56 rifampicin
rpoC 765292 c.1923G>T synonymous_variant 0.67 rifampicin
rpoC 765300 p.Val644Ala missense_variant 0.67 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoC 765328 p.His653Gln missense_variant 0.76 rifampicin Uncertain significance
rpoC 765330 p.Ser654Asn missense_variant 0.76 rifampicin Uncertain significance
rpoC 765334 c.1965C>T synonymous_variant 0.74 rifampicin
rpoC 765343 c.1974G>A synonymous_variant 0.76 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 0.74 rifampicin Not assoc w R - Interim
rpoC 765367 c.1998C>G synonymous_variant 0.76 rifampicin
rpoC 765370 c.2001G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765383 p.Met672Leu missense_variant 0.8 rifampicin Uncertain significance
rpoC 765391 c.2022C>T synonymous_variant 0.82 rifampicin
rpoC 765406 c.2037G>T synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoC 765409 c.2040T>C synonymous_variant 0.85 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 0.87 rifampicin
rpoC 765421 c.2052C>G synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765452 c.2083_2085delGCCinsTG frameshift_variant&missense_variant 0.86 rifampicin
rpoC 765466 c.2097C>T synonymous_variant 0.85 rifampicin
rpoC 765478 c.2109T>C synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 0.89 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765517 c.2148C>G synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoC 765529 c.2160C>T synonymous_variant 0.91 rifampicin
rpoC 765541 c.2172C>G synonymous_variant 0.88 rifampicin
rpoC 765553 c.2184C>T synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 765556 c.2187G>C synonymous_variant 0.9 rifampicin
rpoC 765562 c.2193G>C synonymous_variant 0.89 rifampicin
rpoC 765578 c.2209C>T synonymous_variant 0.89 rifampicin
rpoC 765622 p.Glu751Asp missense_variant 0.87 rifampicin
rpoC 765625 c.2256C>T synonymous_variant 0.86 rifampicin
rpoC 765628 c.2259G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 765658 c.2289C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 765670 c.2301C>T synonymous_variant 0.86 rifampicin
rpoC 765700 c.2331T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 765728 p.Gln787Lys missense_variant 0.81 rifampicin
rpoC 765734 c.2365T>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765739 c.2370G>C synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoC 765752 p.Asp795Ser missense_variant 0.77 rifampicin
rpoC 765772 c.2403C>G synonymous_variant 0.73 rifampicin
rpoC 765784 c.2415C>G synonymous_variant 0.72 rifampicin
rpoC 765790 c.2421C>T synonymous_variant 0.72 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 0.74 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 0.74 rifampicin
rpoC 765814 c.2445A>G synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoC 765826 c.2457T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765883 c.2514C>G synonymous_variant 0.76 rifampicin
rpoC 765886 c.2517C>G synonymous_variant 0.77 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.77 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.85 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.79 rifampicin
rpoC 765994 c.2625A>T synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoC 766012 c.2643C>G synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoC 766021 c.2652G>C synonymous_variant 0.8 rifampicin
rpoC 766061 p.Val898Ile missense_variant 0.69 rifampicin
rpoC 766082 p.Ala905Gln missense_variant 0.67 rifampicin
rpoC 766093 c.2724C>A synonymous_variant 0.7 rifampicin
rpoC 766095 p.Thr909Ser missense_variant 0.7 rifampicin
rpoC 766105 c.2736C>T synonymous_variant 0.68 rifampicin
rpoC 766123 c.2754C>A synonymous_variant 0.71 rifampicin
rpoC 766129 c.2760C>G synonymous_variant 0.7 rifampicin
rpoC 766135 c.2766G>A synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoC 766141 c.2772C>T synonymous_variant 0.58 rifampicin
rpoC 766142 c.2773C>T synonymous_variant 0.58 rifampicin Not assoc w R - Interim
rpoC 766147 c.2778C>T synonymous_variant 0.44 rifampicin
rpoC 766148 p.Thr927Ala missense_variant 0.47 rifampicin Uncertain significance
rpoC 766270 c.2901G>C synonymous_variant 0.62 rifampicin
rpoC 766273 c.2904T>C synonymous_variant 0.62 rifampicin
rpoC 766274 p.Ala969Thr missense_variant 0.62 rifampicin
rpoC 766280 c.2911_2913delAGCinsGT frameshift_variant&missense_variant 0.64 rifampicin
rpoC 766288 c.2919C>G synonymous_variant 0.74 rifampicin
rpoC 766309 c.2940G>A synonymous_variant 0.85 rifampicin
rpoC 766315 c.2946C>G synonymous_variant 0.85 rifampicin
rpoC 766321 c.2952C>G synonymous_variant 0.83 rifampicin
rpoC 766348 c.2979A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoC 766369 c.3000C>G synonymous_variant 0.84 rifampicin
rpoC 766381 c.3012C>T synonymous_variant 0.89 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.89 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.91 rifampicin
rpoC 766402 c.3033C>G synonymous_variant 0.92 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766426 c.3057C>T synonymous_variant 0.9 rifampicin
rpoC 766456 c.3087C>G synonymous_variant 0.86 rifampicin
rpoC 766486 c.3117A>G synonymous_variant 0.85 rifampicin
rpoC 766492 c.3123T>C synonymous_variant 0.85 rifampicin
rpoC 766522 c.3153C>G synonymous_variant 0.82 rifampicin
rpoC 766528 c.3159T>C synonymous_variant 0.83 rifampicin
rpoC 766530 p.Arg1054Gln missense_variant 0.83 rifampicin
rpoC 766549 c.3180G>C synonymous_variant 0.83 rifampicin
rpoC 766573 c.3204T>C synonymous_variant 0.86 rifampicin
rpoC 766585 c.3216T>C synonymous_variant 0.84 rifampicin
rpoC 766594 c.3225G>C synonymous_variant 0.87 rifampicin
rpoC 766607 p.Ile1080Leu missense_variant 0.91 rifampicin
rpoC 766630 c.3261G>T synonymous_variant 0.86 rifampicin
rpoC 766660 c.3291G>A synonymous_variant 0.93 rifampicin
rpoC 766666 c.3297C>G synonymous_variant 0.93 rifampicin
rpoC 766672 c.3303T>C synonymous_variant 0.93 rifampicin
rpoC 766700 c.3331C>T synonymous_variant 0.92 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 0.9 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 0.92 rifampicin
rpoC 766738 c.3369G>C synonymous_variant 0.93 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 0.93 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 0.93 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766774 c.3405T>C synonymous_variant 0.94 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766801 c.3432C>G synonymous_variant 0.91 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.92 rifampicin
rpoC 766876 c.3507C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGC frameshift_variant&missense_variant 0.92 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 0.9 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 0.9 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 0.9 rifampicin
rpoC 766903 c.3534C>T synonymous_variant 0.91 rifampicin
rpoC 766918 c.3549C>T synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 766933 c.3564A>G synonymous_variant 0.86 rifampicin
rpoC 766945 c.3576A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 766963 c.3594T>G synonymous_variant 0.9 rifampicin
rpoC 766996 c.3627C>G synonymous_variant 0.92 rifampicin
rpoC 767002 c.3633G>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.88 rifampicin
rpoC 767014 c.3645G>C synonymous_variant 0.88 rifampicin
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.88 rifampicin
rpoC 767059 c.3690T>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.91 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.93 rifampicin
rpoC 767158 c.3789T>A synonymous_variant 0.9 rifampicin
rpoC 767167 c.3798C>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.92 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767221 c.3852C>G synonymous_variant 0.87 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>G synonymous_variant 0.7 rifampicin
rpoC 767264 p.Ala1299Gln missense_variant 0.67 rifampicin
rpoC 767278 c.3909T>C synonymous_variant 0.65 rifampicin
rpoC 767281 c.3912C>G synonymous_variant 0.65 rifampicin Not assoc w R - Interim
rpoC 767284 c.3915C>T synonymous_variant 0.65 rifampicin
mmpL5 775639 p.Ile948Val missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 0.69 clofazimine
bedaquiline
mmpL5 775864 p.Ala873Ser missense_variant 0.62 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 0.62 clofazimine
bedaquiline
mmpL5 775874 c.2607C>G synonymous_variant 0.64 clofazimine
bedaquiline
mmpL5 775909 p.Leu858Phe missense_variant 0.75 clofazimine
bedaquiline
mmpL5 775910 c.2571G>A synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 775921 c.2560C>T synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775940 c.2541C>T synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 775943 c.2538C>G synonymous_variant 0.71 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.71 clofazimine
bedaquiline
mmpL5 775975 c.2506T>C synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 0.77 clofazimine
bedaquiline
mmpL5 775997 c.2484T>C synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 776000 c.2479_2481delCTGinsAC frameshift_variant&missense_variant 0.63 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776009 c.2472A>G synonymous_variant 0.75 clofazimine
bedaquiline
mmpL5 776030 c.2451G>T synonymous_variant 0.65 clofazimine
bedaquiline
rpsL 781134 c.-426T>C upstream_gene_variant 0.57 streptomycin
rpsL 781138 c.-422C>G upstream_gene_variant 0.55 streptomycin
rpsL 781143 c.-417T>C upstream_gene_variant 0.6 streptomycin
rpsL 781152 c.-408G>A upstream_gene_variant 0.58 streptomycin
rpsL 781164 c.-396T>C upstream_gene_variant 0.53 streptomycin
rpsL 781170 c.-390G>C upstream_gene_variant 0.5 streptomycin
rpsL 781173 c.-387A>G upstream_gene_variant 0.5 streptomycin
rpsL 781174 c.-386C>T upstream_gene_variant 0.5 streptomycin
rpsL 781185 c.-375T>C upstream_gene_variant 0.58 streptomycin
rpsL 781188 c.-372G>C upstream_gene_variant 0.62 streptomycin
rpsL 781189 c.-371T>C upstream_gene_variant 0.62 streptomycin
rpsL 781206 c.-354C>T upstream_gene_variant 0.67 streptomycin
rpsL 781209 c.-351C>G upstream_gene_variant 0.67 streptomycin
rpsL 781224 c.-336T>C upstream_gene_variant 0.62 streptomycin
rpsL 781234 c.-326G>C upstream_gene_variant 0.58 streptomycin
rpsL 781616 c.57C>T synonymous_variant 0.68 streptomycin
rpsL 781628 c.69T>C synonymous_variant 0.72 streptomycin Not assoc w R - Interim
rpsL 781655 c.96T>C synonymous_variant 0.76 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.77 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.84 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.88 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.88 streptomycin
rpsL 781721 c.162C>T synonymous_variant 0.88 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.88 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.89 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.91 streptomycin
rpsL 781754 c.195G>C synonymous_variant 0.91 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.91 streptomycin
rpsL 781766 c.207C>T synonymous_variant 0.92 streptomycin Not assoc w R - Interim
rpsL 781772 c.213C>G synonymous_variant 0.92 streptomycin
rpsL 781793 c.234G>C synonymous_variant 0.92 streptomycin
rpsL 781808 c.249C>T synonymous_variant 0.94 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.9 streptomycin
rpsL 781835 c.276T>C synonymous_variant 0.89 streptomycin Not assoc w R - Interim
rpsL 781859 c.300T>G synonymous_variant 0.84 streptomycin
rpsL 781865 c.306G>C synonymous_variant 0.83 streptomycin
rpsL 781868 c.309T>C synonymous_variant 0.83 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.84 streptomycin
rpsL 781883 c.324G>A synonymous_variant 0.83 streptomycin
rpsL 781886 c.327C>T synonymous_variant 0.83 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.82 streptomycin
rpsL 781898 c.339A>T synonymous_variant 0.82 streptomycin
rpsL 781916 c.357T>C synonymous_variant 0.83 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.85 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.85 streptomycin
rplC 800252 c.-557C>A upstream_gene_variant 0.74 linezolid
rplC 800272 c.-537C>T upstream_gene_variant 0.74 linezolid
rplC 800278 c.-531_-528delAAGCinsGA upstream_gene_variant 0.74 linezolid
rplC 800287 c.-522G>T upstream_gene_variant 0.74 linezolid
rplC 800292 c.-517C>T upstream_gene_variant 0.74 linezolid
rplC 800299 c.-510G>C upstream_gene_variant 0.76 linezolid
rplC 800303 c.-506T>A upstream_gene_variant 0.74 linezolid
rplC 800304 c.-505T>C upstream_gene_variant 0.74 linezolid
rplC 800306 c.-503A>G upstream_gene_variant 0.77 linezolid Uncertain significance
rplC 800307 c.-502T>C upstream_gene_variant 0.76 linezolid
rplC 800312 c.-497A>C upstream_gene_variant 0.76 linezolid
rplC 800329 c.-480C>T upstream_gene_variant 0.72 linezolid
rplC 800341 c.-468G>C upstream_gene_variant 0.6 linezolid
rplC 800344 c.-465_-464insG upstream_gene_variant 0.55 linezolid
rplC 800358 c.-450delT upstream_gene_variant 0.52 linezolid
rplC 800386 c.-423T>C upstream_gene_variant 0.43 linezolid
rplC 800516 c.-293G>T upstream_gene_variant 0.83 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 0.84 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 0.85 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 0.85 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 0.85 linezolid
rplC 800582 c.-227C>T upstream_gene_variant 0.85 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 0.86 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 0.84 linezolid
rplC 800621 c.-188G>A upstream_gene_variant 0.86 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 0.86 linezolid
rplC 800648 c.-161A>G upstream_gene_variant 0.82 linezolid
rplC 800654 c.-155T>C upstream_gene_variant 0.81 linezolid
rplC 800693 c.-116A>G upstream_gene_variant 0.71 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 0.71 linezolid
rplC 800714 c.-95C>T upstream_gene_variant 0.74 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 0.74 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 0.76 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 0.68 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 0.68 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 0.68 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 0.7 linezolid
rplC 800798 c.-11_-8delTGGAinsC upstream_gene_variant 0.62 linezolid
rplC 800806 c.-3G>T upstream_gene_variant 0.5 linezolid
rplC 800807 c.-2_-1insT upstream_gene_variant 0.5 linezolid
rplC 800814 c.6A>G synonymous_variant 0.5 linezolid
rplC 800815 c.7C>A synonymous_variant 0.53 linezolid
rplC 800820 c.12G>A synonymous_variant 0.5 linezolid
rplC 800829 c.21C>G synonymous_variant 0.5 linezolid
rplC 800844 c.36T>C synonymous_variant 0.59 linezolid
rplC 800856 c.48A>G synonymous_variant 0.56 linezolid
rplC 800865 c.57A>G synonymous_variant 0.48 linezolid
rplC 800867 p.Ser20Asn missense_variant 0.48 linezolid
rplC 800872 c.64_66delAGAinsCG frameshift_variant&synonymous_variant 0.44 linezolid
rplC 800877 c.69A>C synonymous_variant 0.44 linezolid
rplC 800880 c.72A>G synonymous_variant 0.44 linezolid
rplC 800901 c.93C>G synonymous_variant 0.4 linezolid
rplC 801171 c.363A>G synonymous_variant 0.77 linezolid
rplC 801180 c.372C>G synonymous_variant 0.73 linezolid
rplC 801195 c.387G>C synonymous_variant 0.86 linezolid
rplC 801201 c.393C>T synonymous_variant 0.86 linezolid
rplC 801207 c.399C>T synonymous_variant 0.82 linezolid
rplC 801210 c.402T>C synonymous_variant 0.82 linezolid
rplC 801222 c.414T>C synonymous_variant 0.82 linezolid
rplC 801228 c.420T>C synonymous_variant 0.8 linezolid
rplC 801231 c.423C>T synonymous_variant 0.81 linezolid
rplC 801246 c.438C>T synonymous_variant 0.84 linezolid
rplC 801255 c.447C>A synonymous_variant 0.83 linezolid
rplC 801267 c.459A>C synonymous_variant 0.83 linezolid
rplC 801270 c.462T>C synonymous_variant 0.83 linezolid
rplC 801273 c.465C>G synonymous_variant 0.84 linezolid
rplC 801279 c.471G>C synonymous_variant 0.84 linezolid
rplC 801285 c.477G>A synonymous_variant 0.79 linezolid
rplC 801309 c.501C>G synonymous_variant 0.75 linezolid
rplC 801312 c.504G>C synonymous_variant 0.75 linezolid
rplC 801324 c.516T>C synonymous_variant 0.73 linezolid
rplC 801330 c.522G>T synonymous_variant 0.73 linezolid
rplC 801333 c.525G>C synonymous_variant 0.71 linezolid
rplC 801339 c.531T>G synonymous_variant 0.69 linezolid
rplC 801341 p.Leu178Gln missense_variant 0.69 linezolid
rplC 801348 c.540T>G synonymous_variant 0.68 linezolid
rplC 801349 p.Leu181Val missense_variant 0.68 linezolid
rplC 801357 c.549T>C synonymous_variant 0.71 linezolid
rplC 801372 c.564G>A synonymous_variant 0.7 linezolid
rplC 801385 c.577C>T synonymous_variant 0.59 linezolid
rplC 801402 c.594T>C synonymous_variant 0.33 linezolid
rplC 801405 c.597T>C synonymous_variant 0.35 linezolid
fbiC 1303417 p.Gly163Ser missense_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1303422 c.492A>G synonymous_variant 0.32 clofazimine
pretomanid
delamanid
fbiC 1303425 c.495G>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303431 c.501T>C synonymous_variant 0.38 clofazimine
pretomanid
delamanid
fbiC 1303437 c.507C>G synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303441 c.511T>C synonymous_variant 0.4 clofazimine
pretomanid
delamanid
fbiC 1303449 c.519C>T synonymous_variant 0.69 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303470 c.540T>G synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303506 c.576C>T synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303534 p.Ser202Ala missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303538 p.Arg203Leu missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1303575 c.645G>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303578 c.648G>A synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303596 c.666G>C synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303605 c.675C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303608 c.678G>A synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303617 c.687C>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303620 c.690C>T synonymous_variant 0.91 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303629 c.699C>T synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 0.89 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303661 p.Val244Ala missense_variant 0.9 clofazimine
pretomanid
delamanid
fbiC 1303674 c.744C>G synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1303686 c.756C>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303704 c.774T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303708 c.778T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303732 p.Ser268Ala missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303737 c.807G>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1303746 c.816T>C synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303755 c.825T>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1303779 c.849G>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303782 c.852C>T synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1303785 c.855G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1303788 c.858T>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1303800 c.870G>C synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1303812 c.882C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1303818 c.888C>G synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1303844 p.Ala305Gly missense_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303854 c.924T>C synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303860 c.930A>T synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiC 1303869 c.939T>C synonymous_variant 0.55 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303881 c.951G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303890 c.960G>C synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303893 c.963G>A synonymous_variant 0.6 clofazimine
pretomanid
delamanid
fbiC 1303905 c.975G>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304019 c.1089C>T synonymous_variant 0.79 clofazimine
pretomanid
delamanid
fbiC 1304022 c.1092T>C synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304046 c.1116C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304055 c.1125C>T synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304061 c.1131G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304063 p.Ala378Asp missense_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304068 p.Val380Ile missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304085 c.1155C>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304087 p.Tyr386Phe missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304091 c.1161C>T synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304092 p.Met388Leu missense_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304104 c.1174C>T synonymous_variant 0.72 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304109 c.1179C>T synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304112 c.1182G>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304115 c.1185A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304133 c.1203G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304136 c.1206C>G synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304139 c.1209G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304142 c.1212G>C synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiC 1304481 c.1551T>G synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304496 c.1566T>A synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 0.8 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304502 c.1572G>C synonymous_variant 0.81 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304532 c.1602G>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304541 c.1611C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304544 c.1614T>C synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304546 p.Val539Ala missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 0.92 clofazimine
pretomanid
delamanid
fbiC 1304574 c.1644C>G synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304610 c.1680C>G synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>A synonymous_variant 0.83 clofazimine
pretomanid
delamanid
fbiC 1304625 c.1695C>T synonymous_variant 0.8 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 0.75 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304672 p.Val581Ala missense_variant 0.65 clofazimine
pretomanid
delamanid
fbiC 1304674 p.Gly582Gln missense_variant 0.63 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>A synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.62 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304797 p.Ala623Asn missense_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.66 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 0.75 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304853 c.1923C>G synonymous_variant 0.76 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304856 c.1926C>G synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304868 c.1938G>C synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304871 c.1941G>T synonymous_variant 0.76 clofazimine
pretomanid
delamanid
fbiC 1304872 c.1942_1943delAGinsTC synonymous_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304875 p.Ile649Val missense_variant 0.78 clofazimine
pretomanid
delamanid
fbiC 1304883 c.1953G>A synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304893 p.Gly655Ser missense_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304915 p.Asp662Gly missense_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304928 c.1998T>C synonymous_variant 0.91 clofazimine
pretomanid
delamanid
fbiC 1304934 c.2004C>G synonymous_variant 0.88 clofazimine
pretomanid
delamanid
fbiC 1304937 c.2007G>C synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304946 c.2016G>C synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304955 c.2025G>A synonymous_variant 0.87 clofazimine
pretomanid
delamanid
fbiC 1304958 c.2028T>G synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304982 c.2052G>A synonymous_variant 0.86 clofazimine
pretomanid
delamanid
fbiC 1304991 c.2061G>C synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304994 c.2064A>G synonymous_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1304995 p.Leu689Met missense_variant 0.84 clofazimine
pretomanid
delamanid
fbiC 1305006 c.2076A>G synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1305012 c.2082G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1305015 c.2085G>C synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1305021 c.2091C>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fbiC 1305033 c.2103T>C synonymous_variant 0.77 clofazimine
pretomanid
delamanid
fbiC 1305039 c.2109G>A synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305042 c.2112A>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305045 c.2115A>G synonymous_variant 0.72 clofazimine
pretomanid
delamanid
fbiC 1305354 c.2424C>T synonymous_variant 0.52 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305357 c.2427C>G synonymous_variant 0.52 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1305361 c.2431C>T synonymous_variant 0.54 clofazimine
pretomanid
delamanid
fbiC 1305393 c.2463T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305397 p.Glu823Gln missense_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305405 c.2475A>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiC 1305414 c.2484G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305417 c.2487C>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305423 c.2493T>G synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305426 c.2496G>A synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305427 c.2497C>T synonymous_variant 0.56 clofazimine
pretomanid
delamanid
fbiC 1305435 c.2505G>C synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1305444 c.2514A>G synonymous_variant 0.64 clofazimine
pretomanid
delamanid
fbiC 1305446 p.Gly839Ala missense_variant 0.64 clofazimine Uncertain significance
pretomanid
delamanid Uncertain significance
sigE 1364667 c.255T>C synonymous_variant 0.38 pyrazinamide
sigE 1364671 c.259C>T synonymous_variant 0.38 pyrazinamide
sigE 1364676 c.264C>G synonymous_variant 0.38 pyrazinamide
sigE 1364677 c.265_267delCGTinsAA frameshift_variant&missense_variant 0.4 pyrazinamide Uncertain significance
sigE 1364691 c.279T>C synonymous_variant 0.48 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 0.52 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.58 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 0.62 pyrazinamide
sigE 1364726 p.Asn105Ser missense_variant 0.62 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.59 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.59 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.61 pyrazinamide
sigE 1364745 c.333C>T synonymous_variant 0.61 pyrazinamide
sigE 1364746 c.334C>T synonymous_variant 0.61 pyrazinamide Not assoc w R - Interim
sigE 1364751 c.339C>G synonymous_variant 0.62 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.62 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.61 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.63 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 0.75 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 0.76 pyrazinamide
sigE 1364802 c.390C>A synonymous_variant 0.76 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.81 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.83 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.89 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.92 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.92 pyrazinamide
sigE 1364868 c.456T>C synonymous_variant 0.92 pyrazinamide
sigE 1364871 c.459C>G synonymous_variant 0.92 pyrazinamide
sigE 1364874 c.462C>T synonymous_variant 0.93 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 0.93 pyrazinamide
sigE 1364889 c.477A>G synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364892 c.480C>G synonymous_variant 0.94 pyrazinamide
sigE 1364913 c.501C>G synonymous_variant 0.96 pyrazinamide
sigE 1364919 c.507T>C synonymous_variant 0.93 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.93 pyrazinamide
sigE 1364928 c.516C>T synonymous_variant 0.93 pyrazinamide
sigE 1364952 c.540A>C synonymous_variant 0.9 pyrazinamide
sigE 1364958 c.546G>C synonymous_variant 0.89 pyrazinamide
sigE 1364961 c.549A>G synonymous_variant 0.89 pyrazinamide
sigE 1364964 c.552T>G synonymous_variant 0.89 pyrazinamide
sigE 1364967 c.555C>T synonymous_variant 0.89 pyrazinamide
sigE 1364973 c.561G>A synonymous_variant 0.89 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
sigE 1364984 p.Ala191Asp missense_variant 0.89 pyrazinamide
sigE 1364988 c.576G>A synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
sigE 1365003 c.591T>C synonymous_variant 0.85 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.85 pyrazinamide
sigE 1365019 c.607C>T synonymous_variant 0.82 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.77 pyrazinamide
sigE 1365033 c.621G>A synonymous_variant 0.75 pyrazinamide
sigE 1365042 c.630G>C synonymous_variant 0.69 pyrazinamide
sigE 1365051 c.639G>A synonymous_variant 0.67 pyrazinamide
embR 1416238 c.1110C>G synonymous_variant 0.39 ethambutol
embR 1416241 c.1107T>C synonymous_variant 0.37 ethambutol
embR 1416247 c.1101C>T synonymous_variant 0.35 ethambutol
embR 1416256 p.Asn364Lys missense_variant 0.41 ethambutol
embR 1416259 c.1089G>C synonymous_variant 0.41 ethambutol
embR 1416262 c.1086G>C synonymous_variant 0.41 ethambutol
embR 1416266 p.Val361Ala missense_variant 0.41 ethambutol
embR 1416274 c.1074C>G synonymous_variant 0.41 ethambutol
embR 1416280 c.1068A>G synonymous_variant 0.41 ethambutol
embR 1416285 p.Glu355Gln missense_variant 0.43 ethambutol
embR 1416289 c.1059G>A synonymous_variant 0.43 ethambutol
embR 1416301 c.1047C>A synonymous_variant 0.43 ethambutol
embR 1416310 c.1038G>C synonymous_variant 0.41 ethambutol
embR 1416313 c.1035A>G synonymous_variant 0.41 ethambutol
embR 1416316 c.1032C>G synonymous_variant 0.41 ethambutol
embR 1416330 p.Val340Ile missense_variant 0.47 ethambutol
embR 1416332 p.Tyr339Phe missense_variant 0.47 ethambutol
embR 1416335 p.Asn338Ser missense_variant 0.47 ethambutol
embR 1416343 c.1005G>C synonymous_variant 0.47 ethambutol
embR 1416364 c.984C>T synonymous_variant 0.5 ethambutol
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.56 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.6 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.56 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.67 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.68 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.71 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.8 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.81 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.85 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.7 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.7 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472445 n.601_604delTCTC non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472451 n.606_607insCGGG non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472460 n.615T>C non_coding_transcript_exon_variant 0.64 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.64 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 0.75 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472686 n.841G>A non_coding_transcript_exon_variant 0.78 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.92 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.92 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTT non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.83 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1473797 n.140G>T non_coding_transcript_exon_variant 0.91 capreomycin
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.8 capreomycin
linezolid
rrl 1473831 n.174G>A non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474061 n.404T>C non_coding_transcript_exon_variant 0.6 capreomycin
linezolid
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.79 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.77 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.83 capreomycin Uncertain significance
linezolid
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1475604 n.1947A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.91 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.93 capreomycin
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.83 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475999 n.2342G>T non_coding_transcript_exon_variant 0.83 capreomycin
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>C non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476047 n.2390G>A non_coding_transcript_exon_variant 0.82 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.82 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476077 n.2420T>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.71 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.69 capreomycin
linezolid
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476105 n.2448_2449delGAinsT non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.8 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.88 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.87 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.92 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.9 capreomycin
linezolid
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.89 capreomycin Uncertain significance
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.85 capreomycin
linezolid
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.84 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.84 capreomycin
linezolid
rrl 1476750 n.3093T>C non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.77 capreomycin
linezolid
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.79 capreomycin
linezolid
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.67 capreomycin
linezolid
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.64 capreomycin
linezolid
inhA 1673499 c.-703T>C upstream_gene_variant 0.59 ethionamide
isoniazid Uncertain significance
inhA 1673505 c.-697A>T upstream_gene_variant 0.6 ethionamide
isoniazid
inhA 1673517 c.-685G>C upstream_gene_variant 0.63 ethionamide
isoniazid
inhA 1673524 c.-678C>T upstream_gene_variant 0.63 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 0.66 ethionamide
isoniazid
inhA 1673565 c.-637G>C upstream_gene_variant 0.65 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 0.61 ethionamide
isoniazid Uncertain significance
inhA 1673589 c.-613A>G upstream_gene_variant 0.65 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 0.65 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 0.65 ethionamide
isoniazid
inhA 1673604 c.-598G>C upstream_gene_variant 0.65 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 0.65 ethionamide
isoniazid
fabG1 1673615 p.Glu59Val missense_variant 0.67 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 0.55 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 0.58 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 0.57 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 0.57 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 0.55 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 0.57 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 0.67 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673697 c.-505G>C upstream_gene_variant 0.65 ethionamide
isoniazid
fabG1 1673710 c.271_273delCTAinsAC frameshift_variant&missense_variant 0.65 ethionamide
isoniazid
fabG1 1673716 p.Ala93Lys missense_variant 0.65 ethionamide
isoniazid
inhA 1673724 c.-478A>C upstream_gene_variant 0.71 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1673730 c.-472C>G upstream_gene_variant 0.65 ethionamide
isoniazid
fabG1 1673733 p.Met98Ile missense_variant 0.65 ethionamide
isoniazid
inhA 1673745 c.-457G>A upstream_gene_variant 0.62 ethionamide
isoniazid
inhA 1673748 c.-454A>G upstream_gene_variant 0.62 ethionamide
isoniazid
fabG1 1673749 p.Lys104Arg missense_variant 0.62 ethionamide
isoniazid
fabG1 1673758 p.Lys107Glu missense_variant 0.66 ethionamide
isoniazid
inhA 1673784 c.-418G>C upstream_gene_variant 0.72 ethionamide
isoniazid
inhA 1673793 c.-409G>A upstream_gene_variant 0.74 ethionamide
isoniazid
inhA 1673799 c.-403T>C upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673802 c.-400A>G upstream_gene_variant 0.73 ethionamide
isoniazid
inhA 1673808 c.-394A>G upstream_gene_variant 0.74 ethionamide
isoniazid
fabG1 1673829 p.Asn130Lys missense_variant 0.7 ethionamide
isoniazid
fabG1 1673830 p.Lys131Arg missense_variant 0.7 ethionamide
isoniazid
inhA 1673838 c.-364T>C upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673841 c.-361A>G upstream_gene_variant 0.7 ethionamide
isoniazid
fabG1 1673844 p.Met135Ile missense_variant 0.68 ethionamide
isoniazid
inhA 1673847 c.-355A>C upstream_gene_variant 0.7 ethionamide
isoniazid
inhA 1673853 c.-349A>C upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673856 c.-346T>G upstream_gene_variant 0.71 ethionamide
isoniazid
inhA 1673865 c.-337C>G upstream_gene_variant 0.72 ethionamide
isoniazid
fabG1 1673870 p.Ser144Met missense_variant 0.74 ethionamide
isoniazid
inhA 1673877 c.-325C>T upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1673901 c.-301A>C upstream_gene_variant 0.79 ethionamide
isoniazid
inhA 1673904 c.-298C>G upstream_gene_variant 0.79 ethionamide
isoniazid
fabG1 1673905 p.Ser156Ala missense_variant 0.79 ethionamide
isoniazid
inhA 1673916 c.-286A>C upstream_gene_variant 0.8 ethionamide
isoniazid
fabG1 1673917 p.Val160Leu missense_variant 0.8 ethionamide
isoniazid
inhA 1673922 c.-280T>C upstream_gene_variant 0.8 ethionamide
isoniazid
inhA 1673925 c.-277C>G upstream_gene_variant 0.79 ethionamide
isoniazid
fabG1 1673941 p.Ala168Ser missense_variant 0.78 ethionamide
isoniazid
inhA 1673946 c.-256C>G upstream_gene_variant 0.78 ethionamide
isoniazid
inhA 1673955 c.-247G>C upstream_gene_variant 0.74 ethionamide
isoniazid
fabG1 1674006 p.Asp189Glu missense_variant 0.67 ethionamide
isoniazid
inhA 1674015 c.-187C>G upstream_gene_variant 0.62 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.7 ethionamide
isoniazid
inhA 1674489 c.288G>T synonymous_variant 0.77 ethionamide
isoniazid
inhA 1674507 c.306G>A synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 0.72 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674537 c.336C>A synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674540 c.339C>T synonymous_variant 0.72 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.72 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.7 ethionamide
isoniazid
inhA 1674555 c.354G>A synonymous_variant 0.7 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674561 c.360C>T synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674585 c.384T>C synonymous_variant 0.81 ethionamide
isoniazid
inhA 1674588 c.387G>A synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674589 p.Met130Leu missense_variant 0.82 ethionamide
isoniazid
inhA 1674601 p.Leu134Val missense_variant 0.83 ethionamide
isoniazid
inhA 1674618 c.417C>T synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674624 c.423A>T synonymous_variant 0.79 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674655 c.454_456delAGCinsTCG synonymous_variant 0.74 ethionamide
isoniazid
inhA 1674669 c.468G>C synonymous_variant 0.76 ethionamide
isoniazid
inhA 1674687 c.486G>A synonymous_variant 0.79 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674690 c.489C>G synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674693 c.492C>T synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674696 c.495G>A synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 0.78 ethionamide
isoniazid
inhA 1674717 c.516C>T synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674729 c.528G>A synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674745 p.Tyr182Ala missense_variant 0.86 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 0.85 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674765 c.564C>T synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674774 c.573A>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674777 c.576C>A synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674792 c.591G>C synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674801 c.600T>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674820 c.619_621delCTCinsTG frameshift_variant&missense_variant 0.86 ethionamide
isoniazid
inhA 1674828 c.627G>A synonymous_variant 0.86 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 0.89 ethionamide
isoniazid
inhA 1674870 c.669T>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674876 c.675C>G synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674879 c.678T>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674888 c.687C>T synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 0.87 ethionamide
isoniazid
inhA 1674909 c.708G>C synonymous_variant 0.87 ethionamide
isoniazid
inhA 1674915 c.714C>G synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674939 c.738G>A synonymous_variant 0.88 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674942 c.741T>C synonymous_variant 0.9 ethionamide
isoniazid
inhA 1674966 c.765T>C synonymous_variant 0.89 ethionamide
isoniazid
inhA 1674967 p.Asp256Thr missense_variant 0.89 ethionamide
isoniazid
inhA 1674993 c.792G>C synonymous_variant 0.82 ethionamide
isoniazid
inhA 1674994 p.His265Ser missense_variant 0.82 ethionamide
isoniazid
inhA 1675006 c.805_807delCTCinsTG frameshift_variant&missense_variant 0.74 ethionamide
isoniazid
rpsA 1833256 c.-286C>G upstream_gene_variant 0.88 pyrazinamide
rpsA 1833262 c.-280T>C upstream_gene_variant 0.88 pyrazinamide
rpsA 1833273 c.-269G>A upstream_gene_variant 0.9 pyrazinamide
rpsA 1833277 c.-265C>G upstream_gene_variant 0.95 pyrazinamide
rpsA 1833283 c.-259C>G upstream_gene_variant 0.81 pyrazinamide
rpsA 1833288 c.-254_-253delTGinsCC upstream_gene_variant 0.8 pyrazinamide
rpsA 1833304 c.-238C>G upstream_gene_variant 0.75 pyrazinamide
rpsA 1833310 c.-232T>C upstream_gene_variant 0.75 pyrazinamide
rpsA 1833319 c.-223C>G upstream_gene_variant 0.75 pyrazinamide
rpsA 1833340 c.-202G>C upstream_gene_variant 0.75 pyrazinamide
rpsA 1833343 c.-199G>C upstream_gene_variant 0.75 pyrazinamide
rpsA 1833352 c.-190C>G upstream_gene_variant 0.69 pyrazinamide
rpsA 1833356 c.-186_-185delAGinsTC upstream_gene_variant 0.64 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>T synonymous_variant 0.71 pyrazinamide
rpsA 1833595 c.54T>C synonymous_variant 0.7 pyrazinamide
rpsA 1833613 c.72C>A synonymous_variant 0.77 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 0.77 pyrazinamide
rpsA 1833661 c.120A>G synonymous_variant 0.83 pyrazinamide
rpsA 1833667 c.126C>G synonymous_variant 0.82 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1833724 c.183C>G synonymous_variant 0.73 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 0.74 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 0.8 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
rpsA 1833790 c.249T>C synonymous_variant 0.8 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 0.81 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.84 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.85 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.84 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.84 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.84 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.84 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.87 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.88 pyrazinamide
rpsA 1833859 c.318C>T synonymous_variant 0.87 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.88 pyrazinamide
rpsA 1833895 c.354G>C synonymous_variant 0.86 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.85 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.82 pyrazinamide
rpsA 1833964 c.423C>T synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
rpsA 1833970 c.429G>A synonymous_variant 0.8 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.83 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.81 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.81 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.71 pyrazinamide
rpsA 1834105 c.564C>T synonymous_variant 0.71 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.77 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 0.77 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 0.78 pyrazinamide
rpsA 1834177 c.636A>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>G synonymous_variant 0.8 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834195 c.654G>C synonymous_variant 0.84 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834225 c.684C>G synonymous_variant 0.84 pyrazinamide
rpsA 1834231 c.690T>G synonymous_variant 0.84 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 0.91 pyrazinamide
rpsA 1834297 c.756C>T synonymous_variant 0.91 pyrazinamide
rpsA 1834303 c.762T>G synonymous_variant 0.91 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 0.91 pyrazinamide
rpsA 1834336 c.795C>G synonymous_variant 0.9 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
rpsA 1834357 c.816T>C synonymous_variant 0.89 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 0.88 pyrazinamide
rpsA 1834396 c.855G>T synonymous_variant 0.89 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 0.87 pyrazinamide
rpsA 1834423 c.882G>T synonymous_variant 0.87 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 0.85 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 0.85 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 0.85 pyrazinamide
rpsA 1834477 c.936C>T synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
rpsA 1834489 c.948T>C synonymous_variant 0.86 pyrazinamide
rpsA 1834519 c.978G>C synonymous_variant 0.82 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 0.84 pyrazinamide
rpsA 1834555 c.1014T>G synonymous_variant 0.83 pyrazinamide
rpsA 1834603 c.1062G>A synonymous_variant 0.78 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.77 pyrazinamide
rpsA 1834612 c.1071G>A synonymous_variant 0.77 pyrazinamide Not assoc w R - Interim
rpsA 1834633 c.1092A>G synonymous_variant 0.76 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 0.75 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 0.73 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 0.76 pyrazinamide
rpsA 1834699 p.Glu386Asp missense_variant 0.71 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.81 pyrazinamide
rpsA 1834747 c.1206A>G synonymous_variant 0.86 pyrazinamide
rpsA 1834751 c.1210_1212delCTTinsAG frameshift_variant&missense_variant 0.9 pyrazinamide Uncertain significance
rpsA 1834756 c.1215G>A synonymous_variant 0.9 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.95 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 0.9 pyrazinamide
rpsA 1834766 p.Lys409Ala missense_variant 0.9 pyrazinamide
rpsA 1834775 p.Ala412Gln missense_variant 0.9 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.91 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.88 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.88 pyrazinamide
rpsA 1834813 c.1272G>T synonymous_variant 0.88 pyrazinamide
tsnR 1853369 c.-237C>T upstream_gene_variant 0.88 linezolid
tsnR 1853370 c.-236_-234delGCAinsTG upstream_gene_variant 0.86 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 0.86 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 0.86 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 0.88 linezolid
tsnR 1853393 c.-213C>T upstream_gene_variant 0.88 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 0.88 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.93 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.9 linezolid
tsnR 1853441 c.-165C>G upstream_gene_variant 0.85 linezolid
tsnR 1853447 c.-159C>G upstream_gene_variant 0.82 linezolid
tsnR 1853450 c.-156G>A upstream_gene_variant 0.82 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 0.82 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 0.78 linezolid
tsnR 1853468 c.-138C>G upstream_gene_variant 0.74 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 0.72 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 0.73 linezolid
tsnR 1853485 c.-121G>C upstream_gene_variant 0.73 linezolid
tsnR 1853493 c.-113G>A upstream_gene_variant 0.72 linezolid
tsnR 1853507 c.-99G>A upstream_gene_variant 0.68 linezolid
tsnR 1853510 c.-96G>C upstream_gene_variant 0.68 linezolid
tsnR 1853522 c.-84C>G upstream_gene_variant 0.72 linezolid
tsnR 1853528 c.-78G>C upstream_gene_variant 0.74 linezolid
tsnR 1853538 c.-68_-66delGAAinsAG upstream_gene_variant 0.67 linezolid
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917951 c.12T>C synonymous_variant 0.58 capreomycin
tlyA 1917957 c.18C>T synonymous_variant 0.58 capreomycin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
tlyA 1917981 c.42G>C synonymous_variant 0.54 capreomycin
tlyA 1917984 c.45C>T synonymous_variant 0.5 capreomycin
tlyA 1917985 c.46C>T synonymous_variant 0.5 capreomycin
tlyA 1917990 c.51G>A synonymous_variant 0.5 capreomycin
tlyA 1917996 c.57A>C synonymous_variant 0.5 capreomycin
tlyA 1917999 c.60T>C synonymous_variant 0.5 capreomycin
tlyA 1918002 c.63A>G synonymous_variant 0.5 capreomycin
tlyA 1918008 c.69C>G synonymous_variant 0.54 capreomycin
tlyA 1918011 c.72G>C synonymous_variant 0.54 capreomycin
tlyA 1918029 c.90C>G synonymous_variant 0.54 capreomycin
tlyA 1918035 c.96G>C synonymous_variant 0.54 capreomycin
tlyA 1918036 p.Arg33Ser missense_variant 0.54 capreomycin
tlyA 1918047 c.108G>C synonymous_variant 0.64 capreomycin
tlyA 1918048 p.Leu37Met missense_variant 0.64 capreomycin
ndh 2101756 c.1287G>C synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2101768 c.1275C>G synonymous_variant 0.69 ethionamide
delamanid
isoniazid
ndh 2101771 c.1272T>C synonymous_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2101774 c.1269T>C synonymous_variant 0.73 ethionamide
delamanid
isoniazid
ndh 2101777 c.1266C>G synonymous_variant 0.73 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101783 c.1260T>G synonymous_variant 0.8 ethionamide
delamanid
isoniazid
ndh 2101795 c.1248G>C synonymous_variant 0.88 ethionamide
delamanid
isoniazid
ndh 2101804 c.1239T>G synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101813 c.1230G>A synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101825 c.1218G>A synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101837 p.Ala402Val missense_variant 0.91 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2101858 p.Ile395Met missense_variant 0.93 ethionamide
delamanid
isoniazid
ndh 2101873 c.1170T>C synonymous_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101879 c.1164C>T synonymous_variant 0.91 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2101890 p.Val385Leu missense_variant 0.91 ethionamide
delamanid
isoniazid
ndh 2101894 c.1149T>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101897 c.1146C>T synonymous_variant 0.9 ethionamide
delamanid
isoniazid
ndh 2101906 c.1137G>C synonymous_variant 0.87 ethionamide
delamanid
isoniazid
ndh 2101912 c.1131G>C synonymous_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2101915 c.1128T>C synonymous_variant 0.86 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2101920 c.1123A>C synonymous_variant 0.86 ethionamide
delamanid
isoniazid
ndh 2101924 c.1119T>G synonymous_variant 0.82 ethionamide
delamanid
isoniazid
ndh 2101930 c.1113C>G synonymous_variant 0.81 ethionamide
delamanid
isoniazid
ndh 2101939 c.1104A>C synonymous_variant 0.76 ethionamide
delamanid
isoniazid
ndh 2101954 c.1089G>A synonymous_variant 0.59 ethionamide
delamanid
isoniazid
ndh 2102599 c.444T>C synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102604 c.439T>C synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2102608 c.433_435delTTGinsCC frameshift_variant&missense_variant 0.4 ethionamide Uncertain significance
delamanid Uncertain significance
isoniazid Uncertain significance
ndh 2102617 c.426C>T synonymous_variant 0.42 ethionamide
delamanid
isoniazid Not assoc w R - Interim
ndh 2102632 c.411C>T synonymous_variant 0.43 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102638 c.405A>G synonymous_variant 0.43 ethionamide
delamanid
isoniazid
ndh 2102644 c.399A>G synonymous_variant 0.48 ethionamide
delamanid
isoniazid
ndh 2102671 c.372T>G synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102674 c.369G>A synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102677 c.366C>G synonymous_variant 0.4 ethionamide
delamanid
isoniazid
ndh 2102683 c.360T>C synonymous_variant 0.42 ethionamide
delamanid
isoniazid
ndh 2102686 c.357G>C synonymous_variant 0.42 ethionamide
delamanid
isoniazid
ndh 2102700 c.343C>T synonymous_variant 0.39 ethionamide
delamanid
isoniazid
ndh 2102715 p.Thr110Pro missense_variant 0.82 ethionamide Uncertain significance
delamanid
isoniazid Uncertain significance
ndh 2102824 c.219G>T synonymous_variant 0.38 ethionamide
delamanid
isoniazid
ndh 2102836 c.207T>C synonymous_variant 0.46 ethionamide
delamanid
isoniazid
ndh 2102842 c.201A>G synonymous_variant 0.46 ethionamide
delamanid
isoniazid
ndh 2102845 c.198A>C synonymous_variant 0.48 ethionamide
delamanid
isoniazid
ndh 2102857 c.186T>C synonymous_variant 0.48 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102863 c.180C>T synonymous_variant 0.5 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102869 c.174G>T synonymous_variant 0.52 ethionamide
delamanid
isoniazid
ndh 2102872 c.171A>G synonymous_variant 0.53 ethionamide
delamanid
isoniazid
ndh 2102878 c.165G>C synonymous_variant 0.53 ethionamide
delamanid
isoniazid
ndh 2102883 c.160C>T synonymous_variant 0.53 ethionamide
delamanid
isoniazid
ndh 2102895 c.148C>T synonymous_variant 0.57 ethionamide Not assoc w R - Interim
delamanid Not assoc w R - Interim
isoniazid Not assoc w R - Interim
ndh 2102902 c.141C>G synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2102908 c.135C>G synonymous_variant 0.57 ethionamide
delamanid
isoniazid
ndh 2102914 c.129C>T synonymous_variant 0.56 ethionamide
delamanid
isoniazid
ndh 2102919 c.124C>T synonymous_variant 0.56 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102929 c.114T>C synonymous_variant 0.58 ethionamide
delamanid
isoniazid
ndh 2102938 p.Arg35His missense_variant 0.62 ethionamide
delamanid
isoniazid
ndh 2102959 c.84C>T synonymous_variant 0.65 ethionamide
delamanid
isoniazid
ndh 2102962 c.81A>C synonymous_variant 0.64 ethionamide
delamanid
isoniazid
ndh 2102971 c.72C>T synonymous_variant 0.5 ethionamide
delamanid
isoniazid
katG 2155071 c.1041T>G synonymous_variant 0.45 isoniazid
katG 2155080 c.1032G>C synonymous_variant 0.56 isoniazid
katG 2155083 c.1029G>C synonymous_variant 0.54 isoniazid
katG 2155086 c.1026G>A synonymous_variant 0.52 isoniazid
katG 2155119 c.993T>C synonymous_variant 0.45 isoniazid
katG 2155131 c.981A>G synonymous_variant 0.47 isoniazid Not assoc w R - Interim
katG 2155134 c.978G>C synonymous_variant 0.48 isoniazid
katG 2155140 c.972C>G synonymous_variant 0.5 isoniazid
katG 2155144 p.Asn323Pro missense_variant 0.47 isoniazid
katG 2155152 c.960A>G synonymous_variant 0.47 isoniazid
katG 2155155 c.957C>G synonymous_variant 0.47 isoniazid
katG 2155185 c.927T>C synonymous_variant 0.43 isoniazid
katG 2155188 p.Thr308Lys missense_variant 0.43 isoniazid
katG 2155191 c.921A>C synonymous_variant 0.43 isoniazid
katG 2155203 c.909G>C synonymous_variant 0.45 isoniazid
katG 2155614 c.498T>G synonymous_variant 0.53 isoniazid
katG 2155626 c.486G>C synonymous_variant 0.56 isoniazid
katG 2155632 c.480A>G synonymous_variant 0.56 isoniazid
katG 2155637 p.Leu159Ile missense_variant 0.59 isoniazid
katG 2155641 p.Lys157Asn missense_variant 0.59 isoniazid Uncertain significance
katG 2155656 c.456G>A synonymous_variant 0.6 isoniazid
katG 2155661 p.Val151Ile missense_variant 0.58 isoniazid
katG 2155680 c.432G>T synonymous_variant 0.72 isoniazid
katG 2155691 c.421T>C synonymous_variant 0.64 isoniazid
katG 2155695 c.417C>G synonymous_variant 0.64 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.7 isoniazid
kasA 2517950 c.-165C>G upstream_gene_variant 0.69 isoniazid
kasA 2517962 c.-153C>G upstream_gene_variant 0.7 isoniazid
kasA 2517965 c.-150C>T upstream_gene_variant 0.7 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 0.72 isoniazid
kasA 2517983 c.-132T>C upstream_gene_variant 0.7 isoniazid
kasA 2517989 c.-126T>G upstream_gene_variant 0.72 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 0.7 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.64 isoniazid
kasA 2518025 c.-90G>C upstream_gene_variant 0.59 isoniazid
kasA 2518031 c.-84G>T upstream_gene_variant 0.59 isoniazid
kasA 2518034 c.-81T>C upstream_gene_variant 0.57 isoniazid
kasA 2518040 c.-75G>T upstream_gene_variant 0.59 isoniazid
kasA 2518041 c.-74T>C upstream_gene_variant 0.59 isoniazid
kasA 2518049 c.-66G>C upstream_gene_variant 0.57 isoniazid
kasA 2518053 c.-62_-60delATTinsCG upstream_gene_variant 0.59 isoniazid
kasA 2518073 c.-42T>G upstream_gene_variant 0.59 isoniazid
kasA 2518085 c.-30C>T upstream_gene_variant 0.52 isoniazid
kasA 2518132 c.18C>T synonymous_variant 0.61 isoniazid
kasA 2518138 c.24T>C synonymous_variant 0.63 isoniazid
kasA 2518146 p.Phe11Tyr missense_variant 0.67 isoniazid
kasA 2518152 p.Ser13Asn missense_variant 0.68 isoniazid
kasA 2518162 c.48G>A synonymous_variant 0.81 isoniazid
kasA 2518169 p.Val19Leu missense_variant 0.81 isoniazid
kasA 2518172 c.58_60delACAinsGG frameshift_variant&missense_variant 0.81 isoniazid
kasA 2518190 p.Ser26Ala missense_variant 0.88 isoniazid
kasA 2518199 p.Ile29Val missense_variant 0.91 isoniazid
kasA 2518219 c.105T>C synonymous_variant 0.88 isoniazid
kasA 2518220 c.106C>T synonymous_variant 0.84 isoniazid
kasA 2518245 p.His44Arg missense_variant 0.88 isoniazid
kasA 2518248 p.Ala45Val missense_variant 0.88 isoniazid
kasA 2518261 p.Glu49Asp missense_variant 0.88 isoniazid
kasA 2518273 c.159G>A synonymous_variant 0.86 isoniazid
kasA 2518279 p.Asp55Glu missense_variant 0.8 isoniazid
kasA 2518282 c.168A>G synonymous_variant 0.8 isoniazid
kasA 2518283 p.Ala57Pro missense_variant 0.8 isoniazid
kasA 2518289 p.Lys59Gln missense_variant 0.75 isoniazid
kasA 2518297 c.183C>T synonymous_variant 0.81 isoniazid
kasA 2518492 c.378C>T synonymous_variant 0.67 isoniazid
kasA 2518504 c.390T>C synonymous_variant 0.67 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 0.7 isoniazid
kasA 2518519 c.405G>C synonymous_variant 0.71 isoniazid
kasA 2518528 c.414C>G synonymous_variant 0.74 isoniazid
kasA 2518534 c.420G>C synonymous_variant 0.74 isoniazid
kasA 2518561 c.447T>C synonymous_variant 0.83 isoniazid
kasA 2518567 c.453G>C synonymous_variant 0.82 isoniazid
kasA 2518570 c.456G>C synonymous_variant 0.82 isoniazid
kasA 2518573 c.459G>C synonymous_variant 0.82 isoniazid
kasA 2518574 p.Ile154Val missense_variant 0.82 isoniazid
kasA 2518582 c.468G>C synonymous_variant 0.78 isoniazid
kasA 2518583 c.469_471delCAGinsGA frameshift_variant&missense_variant 0.78 isoniazid
kasA 2518594 c.480C>T synonymous_variant 0.83 isoniazid
kasA 2518597 c.483C>G synonymous_variant 0.82 isoniazid
kasA 2518606 c.492G>C synonymous_variant 0.84 isoniazid
kasA 2518609 p.Met165Ile missense_variant 0.85 isoniazid
kasA 2518636 c.522C>A synonymous_variant 0.93 isoniazid
kasA 2518639 c.525G>C synonymous_variant 0.92 isoniazid
kasA 2518642 c.528A>G synonymous_variant 0.92 isoniazid
kasA 2518645 c.531G>C synonymous_variant 0.88 isoniazid
kasA 2518651 c.537C>G synonymous_variant 0.89 isoniazid
kasA 2518657 c.543G>C synonymous_variant 0.9 isoniazid
kasA 2518663 c.549T>C synonymous_variant 0.94 isoniazid
kasA 2518672 c.558G>C synonymous_variant 0.94 isoniazid
kasA 2518678 c.564C>T synonymous_variant 0.93 isoniazid
kasA 2518681 c.567C>T synonymous_variant 0.93 isoniazid
kasA 2518684 c.570C>G synonymous_variant 0.93 isoniazid
kasA 2518687 p.Asp191Glu missense_variant 0.93 isoniazid
kasA 2518693 c.579C>G synonymous_variant 0.9 isoniazid
kasA 2518702 c.588C>T synonymous_variant 0.91 isoniazid
kasA 2518711 c.597A>G synonymous_variant 0.91 isoniazid
kasA 2518714 c.600A>C synonymous_variant 0.89 isoniazid
kasA 2518717 c.603C>G synonymous_variant 0.86 isoniazid
kasA 2518723 c.609G>A synonymous_variant 0.88 isoniazid
kasA 2518735 c.621C>T synonymous_variant 0.88 isoniazid
kasA 2518747 c.633C>G synonymous_variant 0.87 isoniazid
kasA 2518768 c.654C>G synonymous_variant 0.83 isoniazid
kasA 2518783 c.669T>C synonymous_variant 0.82 isoniazid
kasA 2518789 c.675G>C synonymous_variant 0.82 isoniazid
kasA 2518795 c.681C>A synonymous_variant 0.82 isoniazid
kasA 2518798 c.684G>C synonymous_variant 0.82 isoniazid
kasA 2518825 c.711T>C synonymous_variant 0.81 isoniazid
kasA 2518840 c.726C>G synonymous_variant 0.79 isoniazid
kasA 2518843 c.729T>G synonymous_variant 0.79 isoniazid
kasA 2518846 c.732G>C synonymous_variant 0.79 isoniazid
kasA 2518855 c.741C>G synonymous_variant 0.78 isoniazid
kasA 2518864 c.750G>C synonymous_variant 0.76 isoniazid
kasA 2518879 c.765A>G synonymous_variant 0.76 isoniazid
kasA 2518885 c.771T>C synonymous_variant 0.75 isoniazid
kasA 2518894 c.780G>A synonymous_variant 0.71 isoniazid
kasA 2518898 c.784T>C synonymous_variant 0.71 isoniazid
kasA 2518906 c.792A>G synonymous_variant 0.69 isoniazid
kasA 2518907 c.793T>C synonymous_variant 0.69 isoniazid
kasA 2518910 p.Leu266Met missense_variant 0.69 isoniazid
kasA 2518915 c.801T>C synonymous_variant 0.69 isoniazid
kasA 2518930 c.816G>C synonymous_variant 0.67 isoniazid
kasA 2518939 c.825T>C synonymous_variant 0.62 isoniazid
kasA 2519044 c.930G>A synonymous_variant 0.58 isoniazid
kasA 2519056 c.942G>A synonymous_variant 0.74 isoniazid
kasA 2519062 c.948T>G synonymous_variant 0.74 isoniazid
kasA 2519072 p.Ala320Thr missense_variant 0.74 isoniazid
kasA 2519077 c.963G>A synonymous_variant 0.74 isoniazid
kasA 2519095 c.981C>G synonymous_variant 0.74 isoniazid
kasA 2519098 c.984C>T synonymous_variant 0.76 isoniazid
kasA 2519104 c.990T>A synonymous_variant 0.76 isoniazid
kasA 2519107 c.993T>C synonymous_variant 0.78 isoniazid
kasA 2519110 p.Asp332Glu missense_variant 0.78 isoniazid
kasA 2519112 p.Gln333Arg missense_variant 0.78 isoniazid
kasA 2519119 c.1005G>C synonymous_variant 0.78 isoniazid
kasA 2519134 c.1020G>A synonymous_variant 0.83 isoniazid
kasA 2519137 c.1023T>G synonymous_variant 0.83 isoniazid
kasA 2519140 c.1026G>A synonymous_variant 0.83 isoniazid
kasA 2519146 c.1032C>A synonymous_variant 0.86 isoniazid
kasA 2519152 c.1038G>C synonymous_variant 0.86 isoniazid
kasA 2519161 c.1047G>A synonymous_variant 0.88 isoniazid
kasA 2519167 c.1053T>G synonymous_variant 0.9 isoniazid
kasA 2519209 c.1095C>T synonymous_variant 0.79 isoniazid
kasA 2519215 c.1101C>T synonymous_variant 0.8 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 0.84 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 0.92 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 0.92 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 0.86 isoniazid
kasA 2519258 c.1144_1146delCTTinsTG frameshift_variant&missense_variant 0.86 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 0.86 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 0.8 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 0.8 isoniazid
kasA 2519273 p.Gly387Ser missense_variant 0.8 isoniazid
kasA 2519278 c.1164A>G synonymous_variant 0.8 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 0.8 isoniazid
kasA 2519287 c.1173T>C synonymous_variant 0.8 isoniazid
kasA 2519293 c.1179T>C synonymous_variant 0.8 isoniazid
kasA 2519295 p.Tyr394Phe missense_variant 0.8 isoniazid
kasA 2519305 c.1191A>G synonymous_variant 0.75 isoniazid
kasA 2519306 p.Val398Ile missense_variant 0.75 isoniazid
kasA 2519317 c.1203G>A synonymous_variant 0.75 isoniazid
kasA 2519338 c.1224T>C synonymous_variant 0.71 isoniazid
kasA 2519344 c.1230G>C synonymous_variant 0.67 isoniazid
kasA 2519347 c.1233T>C synonymous_variant 0.71 isoniazid
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0 isoniazid Not assoc w R
ahpC 2726600 c.408T>C synonymous_variant 0.38 isoniazid
ahpC 2726627 c.435G>A synonymous_variant 0.52 isoniazid
ahpC 2726645 c.453C>G synonymous_variant 0.52 isoniazid
ahpC 2726654 c.462G>C synonymous_variant 0.52 isoniazid Not assoc w R - Interim
ahpC 2726657 c.465A>G synonymous_variant 0.55 isoniazid
ahpC 2726660 c.468C>T synonymous_variant 0.55 isoniazid
ahpC 2726669 c.477T>C synonymous_variant 0.55 isoniazid
ahpC 2726675 c.483A>G synonymous_variant 0.55 isoniazid
ahpC 2726681 c.489A>G synonymous_variant 0.58 isoniazid
ahpC 2726687 c.495C>G synonymous_variant 0.65 isoniazid
ahpC 2726690 c.498C>T synonymous_variant 0.65 isoniazid
ahpC 2726693 c.501C>T synonymous_variant 0.61 isoniazid
ahpC 2726696 c.504C>G synonymous_variant 0.61 isoniazid
ahpC 2726699 c.507G>A synonymous_variant 0.61 isoniazid
ahpC 2726717 c.525A>C synonymous_variant 0.61 isoniazid
folC 2747023 c.576C>G synonymous_variant 0.57 para-aminosalicylic_acid
folC 2747032 c.567A>G synonymous_variant 0.64 para-aminosalicylic_acid
folC 2747047 c.552C>T synonymous_variant 0.67 para-aminosalicylic_acid
folC 2747053 c.546C>T synonymous_variant 0.67 para-aminosalicylic_acid
folC 2747062 c.537A>T synonymous_variant 0.67 para-aminosalicylic_acid
folC 2747086 c.513A>C synonymous_variant 0.65 para-aminosalicylic_acid
folC 2747089 c.510G>C synonymous_variant 0.6 para-aminosalicylic_acid
folC 2747092 p.Asp169Glu missense_variant 0.62 para-aminosalicylic_acid
folC 2747098 c.501C>G synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747107 c.492G>C synonymous_variant 0.62 para-aminosalicylic_acid
folC 2747110 c.489T>C synonymous_variant 0.62 para-aminosalicylic_acid
folC 2747113 c.486C>G synonymous_variant 0.62 para-aminosalicylic_acid
folC 2747132 p.Thr156Val missense_variant 0.59 para-aminosalicylic_acid
folC 2747134 c.465C>G synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747137 c.462G>C synonymous_variant 0.59 para-aminosalicylic_acid
folC 2747161 c.438C>T synonymous_variant 0.5 para-aminosalicylic_acid
Rv2477c 2783278 c.765A>G synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783281 c.762G>C synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783311 c.732T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>A synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783320 c.723C>T synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783332 c.711T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783347 c.696C>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783427 p.Pro206Ala missense_variant 0.86 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783431 c.612C>T synonymous_variant 0.86 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783437 c.606G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783458 c.585G>C synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 0.85 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783512 c.531A>G synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783527 c.516A>G synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783535 c.508C>T synonymous_variant 0.87 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783542 c.501G>A synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783548 c.495T>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783563 c.480A>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783572 c.471A>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783578 c.465G>A synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783602 c.441G>A synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783623 c.420G>A synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783628 p.Ala139Ser missense_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783632 c.411C>G synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783656 c.387G>C synonymous_variant 0.85 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783691 c.352C>T synonymous_variant 0.81 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783700 p.Thr115Ser missense_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 0.88 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783719 c.324A>G synonymous_variant 0.89 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783743 c.300C>G synonymous_variant 0.86 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783751 p.Ile98Val missense_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783758 p.Asp95Glu missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783761 c.282G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783764 c.277_279delATGinsCA frameshift_variant&missense_variant 0.8 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783788 c.255T>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783794 c.249G>A synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783797 p.Asp82Glu missense_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783806 c.237G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783821 p.Gln74Leu missense_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783827 c.216C>T synonymous_variant 0.76 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783833 c.210G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783836 c.207C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783843 p.Gly67Asp missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783846 p.Thr66Asn missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783857 c.186C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783860 c.183T>C synonymous_variant 0.78 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783881 c.160_162delTTGinsCC frameshift_variant&missense_variant 0.85 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783884 c.159T>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783920 c.123G>T synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783938 c.105T>C synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783956 p.Tyr29Phe missense_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783962 c.81T>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783968 c.75G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783971 c.72G>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783980 c.63C>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783992 c.51T>C synonymous_variant 0.72 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2784051 c.-9C>A upstream_gene_variant 0.4 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2681 2996974 p.Glu79Gly missense_variant 0.38 capreomycin
Rv2681 2996987 c.249A>G synonymous_variant 0.48 capreomycin
Rv2681 2997011 c.273C>T synonymous_variant 0.5 capreomycin
Rv2681 2997013 p.Gly92Val missense_variant 0.5 capreomycin
Rv2681 2997021 c.283T>C synonymous_variant 0.49 capreomycin
Rv2681 2997028 p.Val97Ala missense_variant 0.49 capreomycin
Rv2681 2997033 p.Ala99Arg missense_variant 0.49 capreomycin
Rv2681 2997038 c.300G>C synonymous_variant 0.49 capreomycin
Rv2681 2997053 c.315C>G synonymous_variant 0.5 capreomycin
Rv2681 2997054 p.Ser106Gly missense_variant 0.49 capreomycin Uncertain significance
Rv2681 2997060 p.Asn108Asp missense_variant 0.5 capreomycin
Rv2681 2997078 p.Ser114Ala missense_variant 0.55 capreomycin Uncertain significance
Rv2681 2997089 c.351G>A synonymous_variant 0.52 capreomycin
Rv2681 2997092 c.354T>C synonymous_variant 0.5 capreomycin
Rv2681 2997101 c.363T>C synonymous_variant 0.44 capreomycin
Rv2681 2997104 c.366C>G synonymous_variant 0.39 capreomycin
Rv2681 2997116 c.378T>C synonymous_variant 0.36 capreomycin
Rv2681 2997122 c.384A>C synonymous_variant 0.38 capreomycin
Rv2752c 3064989 c.1203G>C synonymous_variant 0.52 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3064998 c.1194A>C synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065040 c.1150_1152delCTCinsTG frameshift_variant&synonymous_variant 0.71 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065049 c.1143G>A synonymous_variant 0.74 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065055 c.1137T>G synonymous_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065064 c.1128G>C synonymous_variant 0.8 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>A synonymous_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065073 c.1119C>G synonymous_variant 0.8 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065085 c.1105_1107delAGGinsCC frameshift_variant&missense_variant 0.83 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065097 c.1095C>T synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065109 c.1081_1083delAGAinsCG frameshift_variant&missense_variant 0.86 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065130 c.1062A>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>C synonymous_variant 0.9 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065154 c.1038G>A synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065190 c.1000_1002delATCinsGG frameshift_variant&missense_variant 0.91 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065199 c.993T>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065205 c.987T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065210 c.982T>C synonymous_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065223 c.969T>C synonymous_variant 0.86 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065229 c.963G>C synonymous_variant 0.82 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065235 c.957G>C synonymous_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065268 c.924A>G synonymous_variant 0.74 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065550 c.642G>C synonymous_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065556 c.636G>T synonymous_variant 0.43 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065562 c.630T>G synonymous_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065580 c.612G>C synonymous_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065595 p.Leu199Phe missense_variant 0.38 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065601 c.591C>T synonymous_variant 0.45 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065614 p.Asp193Gly missense_variant 0.5 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065625 c.567G>A synonymous_variant 0.58 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065637 c.555A>G synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065640 c.552T>C synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065649 c.543T>G synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065659 p.Pro178Leu missense_variant 0.47 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065661 c.531A>G synonymous_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065664 c.526_528delTTGinsCA frameshift_variant&missense_variant 0.47 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065667 c.525A>G synonymous_variant 0.47 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065675 p.Phe173Leu missense_variant 0.44 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065946 p.Gly82Ala missense_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065949 c.243C>T synonymous_variant 0.77 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065957 c.235T>C synonymous_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065963 c.229C>T synonymous_variant 0.82 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065979 c.213T>C synonymous_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 0.83 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065997 c.195C>G synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066006 c.186G>C synonymous_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066017 c.175C>T synonymous_variant 0.87 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066040 p.Gly51Thr missense_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 0.89 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 p.Leu48Met missense_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>G synonymous_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066071 c.121T>C synonymous_variant 0.76 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066081 c.111G>C synonymous_variant 0.56 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066084 c.108C>T synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 0.53 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3066096 c.96G>C synonymous_variant 0.53 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066350 c.-159T>C upstream_gene_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066351 c.-160G>C upstream_gene_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066354 c.-163G>C upstream_gene_variant 0.75 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066365 c.-174C>T upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066366 c.-175C>G upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066387 c.-196G>A upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066399 c.-210_-208delATTinsGC upstream_gene_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066402 c.-211C>T upstream_gene_variant 0.88 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066420 c.-229C>G upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066423 c.-232C>T upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066426 c.-235T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066429 c.-238G>A upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066432 c.-241T>C upstream_gene_variant 0.85 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066437 c.-246G>A upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066459 c.-268T>G upstream_gene_variant 0.84 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066465 c.-276_-274delGGGinsAC upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066471 c.-280A>G upstream_gene_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066474 c.-283G>C upstream_gene_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066477 c.-286C>T upstream_gene_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066480 c.-291_-289delGCCinsTT upstream_gene_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066483 c.-292T>C upstream_gene_variant 0.81 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066501 c.-310G>C upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066513 c.-322C>G upstream_gene_variant 0.83 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066527 c.-336C>T upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066543 c.-352C>A upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066549 c.-358T>C upstream_gene_variant 0.76 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066560 c.-369C>T upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066567 c.-376C>A upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066573 c.-382G>C upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066579 c.-388A>G upstream_gene_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066583 c.-392C>G upstream_gene_variant 0.78 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066597 c.-406C>T upstream_gene_variant 0.8 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066603 c.-412A>G upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066612 c.-421G>A upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066617 c.-426G>A upstream_gene_variant 0.77 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066618 c.-427A>G upstream_gene_variant 0.79 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066633 c.-442T>C upstream_gene_variant 0.73 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066644 c.-453T>C upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066647 c.-456G>A upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066654 c.-463G>C upstream_gene_variant 0.71 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066676 c.-485C>T upstream_gene_variant 0.65 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066685 c.-495_-494delGGinsCC upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066687 c.-496G>T upstream_gene_variant 0.61 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066696 c.-505T>C upstream_gene_variant 0.58 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
thyX 3067652 c.294T>C synonymous_variant 0.69 para-aminosalicylic_acid
thyX 3067661 c.285C>A synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067676 c.270C>G synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067679 p.Cys89Leu missense_variant 0.8 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 0.8 para-aminosalicylic_acid
thyX 3067693 p.Ile85Val missense_variant 0.76 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 0.76 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 0.84 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 0.68 para-aminosalicylic_acid
thyX 3067739 c.207T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyX 3067742 c.204A>C synonymous_variant 0.72 para-aminosalicylic_acid
thyX 3067761 p.Arg62Lys missense_variant 0.64 para-aminosalicylic_acid
thyX 3067765 p.Leu61Ile missense_variant 0.6 para-aminosalicylic_acid
thyX 3067793 c.153T>C synonymous_variant 0.54 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 0.4 para-aminosalicylic_acid
thyX 3067841 c.105G>T synonymous_variant 0.38 para-aminosalicylic_acid
thyA 3073743 c.729T>C synonymous_variant 0.6 para-aminosalicylic_acid
thyA 3073752 p.Glu240Asp missense_variant 0.64 para-aminosalicylic_acid
thyA 3073761 c.711A>G synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073770 c.700_702delGACinsCT frameshift_variant&missense_variant 0.67 para-aminosalicylic_acid
thyA 3073776 c.696A>T synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073781 p.Leu231Phe missense_variant 0.67 para-aminosalicylic_acid
thyA 3073782 c.690A>C synonymous_variant 0.67 para-aminosalicylic_acid
thyA 3073787 p.Lys229Glu missense_variant 0.69 para-aminosalicylic_acid
thyA 3073794 c.678A>G synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3073818 c.652_654delCTGinsAC frameshift_variant&missense_variant 0.74 para-aminosalicylic_acid
thyA 3073824 c.648A>C synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3073827 c.645A>G synonymous_variant 0.71 para-aminosalicylic_acid
thyA 3073830 p.Glu214Asp missense_variant 0.71 para-aminosalicylic_acid
thyA 3073836 c.636C>T synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.74 para-aminosalicylic_acid
thyA 3073854 c.618C>T synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.73 para-aminosalicylic_acid
thyA 3073887 p.Ser195Asp missense_variant 0.71 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3073905 c.567C>G synonymous_variant 0.78 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.81 para-aminosalicylic_acid
thyA 3073944 c.528C>T synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.86 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.83 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 0.82 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 0.88 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.85 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.84 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.77 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.81 para-aminosalicylic_acid
lpqB 3623381 p.Ala510Ile missense_variant 0.73 bedaquiline
rifampicin
lpqB 3623388 p.Thr508Asn missense_variant 0.79 bedaquiline
rifampicin
lpqB 3623393 c.1518A>G synonymous_variant 0.79 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623424 p.Ser496Tyr missense_variant 0.83 bedaquiline
rifampicin
lpqB 3623428 c.1483T>C synonymous_variant 0.75 bedaquiline
rifampicin
lpqB 3623429 c.1482G>C synonymous_variant 0.67 bedaquiline
rifampicin
lpqB 3623438 c.1471_1473delTCGinsAC frameshift_variant&missense_variant 0.64 bedaquiline
rifampicin Uncertain significance
lpqB 3623442 p.Ser490Asn missense_variant 0.64 bedaquiline
rifampicin
lpqB 3623444 c.1467T>C synonymous_variant 0.64 bedaquiline
rifampicin
lpqB 3623461 c.1450C>T synonymous_variant 0.64 bedaquiline
rifampicin
lpqB 3623465 c.1446G>C synonymous_variant 0.64 bedaquiline
rifampicin
lpqB 3623468 c.1443T>C synonymous_variant 0.64 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3623480 c.1431C>G synonymous_variant 0.5 bedaquiline
rifampicin
lpqB 3623483 p.Phe476Tyr missense_variant 0.47 bedaquiline
rifampicin
lpqB 3623489 c.1422C>G synonymous_variant 0.53 bedaquiline
rifampicin
lpqB 3623492 c.1419T>G synonymous_variant 0.53 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3623987 c.924G>C synonymous_variant 0.59 bedaquiline
rifampicin
lpqB 3624008 c.903T>C synonymous_variant 0.74 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624023 c.888G>C synonymous_variant 0.82 bedaquiline
rifampicin
lpqB 3624032 c.879T>C synonymous_variant 0.86 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3624035 c.874_876delAGGinsCA frameshift_variant&missense_variant 0.78 bedaquiline
rifampicin Uncertain significance
lpqB 3624041 p.Glu290Asp missense_variant 0.78 bedaquiline
rifampicin
lpqB 3624050 c.861C>G synonymous_variant 0.78 bedaquiline
rifampicin
lpqB 3624053 c.858C>G synonymous_variant 0.78 bedaquiline
rifampicin
lpqB 3624061 p.Ala284Thr missense_variant 0.78 bedaquiline
rifampicin
lpqB 3624077 c.834G>C synonymous_variant 0.72 bedaquiline
rifampicin
lpqB 3624080 c.829_831delAGGinsCC frameshift_variant&missense_variant 0.69 bedaquiline
rifampicin Uncertain significance
lpqB 3624092 c.817_819delAGGinsCA frameshift_variant&missense_variant 0.63 bedaquiline
rifampicin Uncertain significance
lpqB 3624101 c.810C>G synonymous_variant 0.68 bedaquiline
rifampicin
lpqB 3624107 c.804C>T synonymous_variant 0.68 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624113 c.798G>A synonymous_variant 0.69 bedaquiline
rifampicin
lpqB 3624116 c.795A>G synonymous_variant 0.69 bedaquiline
rifampicin
lpqB 3624125 c.786A>G synonymous_variant 0.57 bedaquiline
rifampicin
lpqB 3624242 c.669A>G synonymous_variant 0.37 bedaquiline
rifampicin
lpqB 3624245 c.666A>G synonymous_variant 0.37 bedaquiline
rifampicin
lpqB 3624254 c.657T>G synonymous_variant 0.4 bedaquiline
rifampicin
lpqB 3624272 c.639G>C synonymous_variant 0.6 bedaquiline
rifampicin
lpqB 3624276 p.Arg212His missense_variant 0.62 bedaquiline
rifampicin
lpqB 3624290 c.621C>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624293 c.618A>G synonymous_variant 0.47 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624296 c.615T>G synonymous_variant 0.47 bedaquiline
rifampicin
lpqB 3624299 c.612G>C synonymous_variant 0.64 bedaquiline
rifampicin
lpqB 3624308 c.603A>G synonymous_variant 0.58 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624311 c.600C>G synonymous_variant 0.58 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624316 p.Val199Ile missense_variant 0.58 bedaquiline
rifampicin
lpqB 3624317 c.594C>G synonymous_variant 0.58 bedaquiline
rifampicin
lpqB 3624320 c.591G>A synonymous_variant 0.58 bedaquiline
rifampicin
lpqB 3624323 c.588G>C synonymous_variant 0.58 bedaquiline
rifampicin
lpqB 3624331 c.580C>T synonymous_variant 0.58 bedaquiline
rifampicin
lpqB 3624339 p.Arg191His missense_variant 0.58 bedaquiline
rifampicin
lpqB 3624346 p.Ser189Ala missense_variant 0.7 bedaquiline
rifampicin
lpqB 3624347 c.564G>C synonymous_variant 0.7 bedaquiline
rifampicin
lpqB 3624356 c.555C>T synonymous_variant 0.62 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624569 c.342C>T synonymous_variant 0.65 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3624572 c.339C>G synonymous_variant 0.67 bedaquiline
rifampicin
lpqB 3624575 c.336T>C synonymous_variant 0.68 bedaquiline
rifampicin
lpqB 3624581 c.330A>C synonymous_variant 0.73 bedaquiline
rifampicin
lpqB 3624594 p.Val106Ala missense_variant 0.73 bedaquiline
rifampicin
lpqB 3624603 p.Lys103Arg missense_variant 0.73 bedaquiline
rifampicin
lpqB 3624605 c.306G>A synonymous_variant 0.73 bedaquiline
rifampicin
lpqB 3624613 p.Ser100Gly missense_variant 0.74 bedaquiline
rifampicin
lpqB 3624614 c.297A>G synonymous_variant 0.71 bedaquiline
rifampicin
lpqB 3624635 c.276C>T synonymous_variant 0.69 bedaquiline
rifampicin
lpqB 3624646 c.265T>C synonymous_variant 0.61 bedaquiline
rifampicin
lpqB 3624649 c.262T>C synonymous_variant 0.61 bedaquiline
rifampicin
lpqB 3624652 p.Ala87Ser missense_variant 0.59 bedaquiline
rifampicin
lpqB 3624656 c.255C>T synonymous_variant 0.56 bedaquiline
rifampicin
lpqB 3624671 c.238_240delGCCinsTG frameshift_variant&missense_variant 0.63 bedaquiline
rifampicin Uncertain significance
lpqB 3624680 c.231T>C synonymous_variant 0.61 bedaquiline
rifampicin
lpqB 3624686 c.223_225delGAAinsCG frameshift_variant&missense_variant 0.61 bedaquiline
rifampicin Uncertain significance
lpqB 3624695 c.216C>T synonymous_variant 0.65 bedaquiline
rifampicin
lpqB 3624701 c.210T>G synonymous_variant 0.65 bedaquiline
rifampicin
lpqB 3624713 c.198C>T synonymous_variant 0.61 bedaquiline
rifampicin
mtrB 3625095 p.Glu507Gln missense_variant 0.77 bedaquiline
rifampicin
lpqB 3625096 c.-186C>T upstream_gene_variant 0.77 bedaquiline
rifampicin
lpqB 3625117 c.-207T>G upstream_gene_variant 0.79 bedaquiline
rifampicin
lpqB 3625123 c.-213T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625138 c.-228C>G upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625147 c.-237C>G upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3625162 c.1452T>C synonymous_variant 0.9 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625183 c.-273G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625186 c.-276T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625189 c.1425A>G synonymous_variant 0.93 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625195 c.-285A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625198 c.-288C>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625201 c.-291T>C upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625207 c.-297C>G upstream_gene_variant 0.9 bedaquiline
rifampicin
lpqB 3625213 c.-303C>T upstream_gene_variant 0.9 bedaquiline
rifampicin
mtrB 3625222 c.1392T>C synonymous_variant 0.89 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625234 c.-324G>A upstream_gene_variant 0.88 bedaquiline
rifampicin
lpqB 3625240 c.-330T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625243 c.-333T>C upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625251 c.-341C>T upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625255 c.-345T>G upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625262 p.Tyr451Phe missense_variant 0.88 bedaquiline
rifampicin
mtrB 3625264 c.1350C>T synonymous_variant 0.88 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625267 c.1347T>C synonymous_variant 0.88 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625273 c.-363C>G upstream_gene_variant 0.87 bedaquiline
rifampicin
lpqB 3625285 c.-375G>C upstream_gene_variant 0.86 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3625301 p.Ala438Gly missense_variant 0.75 bedaquiline
rifampicin
lpqB 3625648 c.-738T>C upstream_gene_variant 0.88 bedaquiline
rifampicin
mtrB 3625656 c.958T>C synonymous_variant 0.83 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 0.85 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625690 c.-780T>G upstream_gene_variant 0.8 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3625699 c.915C>T synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625717 c.-807C>T upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3625747 c.867G>C synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625762 c.-852A>C upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3625765 c.849C>G synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625783 c.-873C>T upstream_gene_variant 0.82 bedaquiline
rifampicin
lpqB 3625801 c.-891G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625849 c.-939T>C upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3625852 c.762A>G synonymous_variant 0.84 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625864 c.-954T>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3625867 c.747A>G synonymous_variant 0.82 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625870 c.-960C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3625876 c.738G>C synonymous_variant 0.79 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625909 c.-999T>C upstream_gene_variant 0.69 bedaquiline
rifampicin
mtrB 3625912 c.702G>C synonymous_variant 0.68 bedaquiline
rifampicin
mtrB 3625915 c.699G>C synonymous_variant 0.64 bedaquiline
rifampicin
mtrB 3625927 c.687T>C synonymous_variant 0.61 bedaquiline
rifampicin
mtrB 3626332 c.282T>C synonymous_variant 0.6 bedaquiline
rifampicin
mtrB 3626344 c.270G>C synonymous_variant 0.65 bedaquiline
rifampicin
mtrB 3626349 p.Ser89Gly missense_variant 0.67 bedaquiline
rifampicin
mtrB 3626353 c.261C>G synonymous_variant 0.7 bedaquiline
rifampicin
mtrB 3626362 c.252A>C synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626368 c.246G>A synonymous_variant 0.67 bedaquiline
rifampicin
mtrB 3626377 p.Asp79Glu missense_variant 0.67 bedaquiline
rifampicin
mtrB 3626383 p.Ala77Gly missense_variant 0.68 bedaquiline
rifampicin
mtrB 3626389 p.Arg75Lys missense_variant 0.71 bedaquiline
rifampicin
mtrB 3626400 p.Ile72Val missense_variant 0.67 bedaquiline
rifampicin
mtrB 3626404 c.210C>T synonymous_variant 0.67 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626407 c.207C>G synonymous_variant 0.64 bedaquiline
rifampicin
mtrB 3626437 c.177T>C synonymous_variant 0.5 bedaquiline
rifampicin
mtrB 3626443 c.171T>G synonymous_variant 0.44 bedaquiline
rifampicin
mtrB 3626470 c.144A>C synonymous_variant 0.48 bedaquiline
rifampicin
mtrB 3626684 c.-71G>A upstream_gene_variant 0.48 bedaquiline
rifampicin
mtrB 3626704 c.-91C>T upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3626750 c.-137T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrA 3626759 c.591T>C synonymous_variant 0.73 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626773 c.-160C>T upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrA 3626774 c.574_576delAGGinsCC frameshift_variant&missense_variant 0.72 bedaquiline
rifampicin
mtrA 3626777 c.573C>T synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626780 c.-167T>C upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3626783 c.-170C>G upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626792 c.558G>T synonymous_variant 0.71 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626798 c.-185T>A upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrA 3626804 c.546A>G synonymous_variant 0.72 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626825 c.525T>A synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626843 c.-230G>A upstream_gene_variant 0.71 bedaquiline
rifampicin
mtrA 3626846 c.504G>A synonymous_variant 0.7 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626849 c.-236C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3626858 c.-245A>G upstream_gene_variant 0.67 bedaquiline
rifampicin
mtrB 3626876 c.-263A>G upstream_gene_variant 0.64 bedaquiline
rifampicin
mtrB 3626885 c.-272A>G upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrB 3626890 c.-277T>C upstream_gene_variant 0.63 bedaquiline
rifampicin
mtrB 3626903 c.-290T>C upstream_gene_variant 0.66 bedaquiline
rifampicin
mtrA 3626912 c.438T>C synonymous_variant 0.72 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626924 c.-311G>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3626927 c.-314G>A upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3626930 c.-317A>G upstream_gene_variant 0.68 bedaquiline
rifampicin
mtrB 3626933 c.-320C>T upstream_gene_variant 0.7 bedaquiline
rifampicin
mtrB 3626942 c.-329A>C upstream_gene_variant 0.72 bedaquiline
rifampicin
mtrB 3626954 c.-341C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626957 c.-344G>C upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3626969 c.-356C>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3626996 c.-383G>A upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3627023 c.-410C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 0.81 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627080 c.270T>C synonymous_variant 0.83 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627098 c.252A>C synonymous_variant 0.77 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627101 c.-488C>G upstream_gene_variant 0.76 bedaquiline
rifampicin
mtrB 3627104 c.-491C>G upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3627110 c.-497G>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627122 c.-509T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrA 3627137 c.211_213delTTGinsCA frameshift_variant&missense_variant 0.78 bedaquiline
rifampicin
mtrB 3627143 c.-530G>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3627181 c.-568T>C upstream_gene_variant 0.74 bedaquiline
rifampicin
mtrB 3627182 c.-569T>C upstream_gene_variant 0.75 bedaquiline
rifampicin
mtrA 3627187 c.163T>C synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3627188 c.162A>G synonymous_variant 0.75 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627197 c.-584T>C upstream_gene_variant 0.77 bedaquiline
rifampicin
mtrB 3627203 c.-590C>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627209 c.-596G>A upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627212 c.-599C>T upstream_gene_variant 0.8 bedaquiline
rifampicin
mtrB 3627218 c.-605G>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrB 3627233 c.-620T>G upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrB 3627236 c.-623T>C upstream_gene_variant 0.79 bedaquiline
rifampicin
mtrA 3627239 c.111C>T synonymous_variant 0.79 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3627254 c.-641C>T upstream_gene_variant 0.81 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 0.85 bedaquiline
rifampicin
mtrB 3627272 c.-659G>C upstream_gene_variant 0.83 bedaquiline
rifampicin
mtrB 3627278 c.-665G>T upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627287 c.-674C>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrB 3627296 c.-683T>G upstream_gene_variant 0.82 bedaquiline
rifampicin
mtrA 3627299 c.49_51delTTGinsCC frameshift_variant&missense_variant 0.81 bedaquiline
rifampicin
mtrB 3627317 c.-704T>C upstream_gene_variant 0.78 bedaquiline
rifampicin
mtrA 3627343 p.Thr3Ser missense_variant 0.73 bedaquiline
rifampicin
fbiB 3642614 c.1080C>T synonymous_variant 0.46 clofazimine
pretomanid
delamanid
fbiB 3642620 c.1086T>C synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiB 3642626 c.1092C>A synonymous_variant 0.53 clofazimine
pretomanid
delamanid
fbiB 3642634 p.Asp367Ala missense_variant 0.59 clofazimine
pretomanid
delamanid
fbiB 3642662 c.1128C>G synonymous_variant 0.55 clofazimine
pretomanid
delamanid
fbiB 3642668 c.1134A>T synonymous_variant 0.68 clofazimine
pretomanid
delamanid
fbiB 3642677 c.1143A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiB 3642680 c.1146A>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiB 3642683 c.1149C>G synonymous_variant 0.71 clofazimine
pretomanid
delamanid
fbiB 3642695 c.1161G>C synonymous_variant 0.73 clofazimine
pretomanid
delamanid
fbiB 3642707 c.1173C>G synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiB 3642710 c.1176G>C synonymous_variant 0.67 clofazimine
pretomanid
delamanid
fbiB 3642743 c.1209T>C synonymous_variant 0.61 clofazimine
pretomanid
delamanid
fbiB 3642749 c.1215T>C synonymous_variant 0.59 clofazimine
pretomanid
delamanid
fbiB 3642758 c.1224C>G synonymous_variant 0.57 clofazimine
pretomanid
delamanid
fbiB 3642767 c.1233G>A synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3642770 c.1236G>C synonymous_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3642772 p.Asp413Gly missense_variant 0.52 clofazimine
pretomanid
delamanid
fbiB 3642775 c.1241_1242insACG disruptive_inframe_insertion 0.52 clofazimine
pretomanid
delamanid
fbiB 3642778 c.1245_1247delAGT disruptive_inframe_deletion 0.55 clofazimine
pretomanid
delamanid
fbiB 3642785 c.1251C>T synonymous_variant 0.52 clofazimine
pretomanid
delamanid
alr 3840458 c.963G>C synonymous_variant 0.67 cycloserine
alr 3840467 c.952_954delGTGinsAC frameshift_variant&missense_variant 0.71 cycloserine
alr 3840470 c.951C>G synonymous_variant 0.71 cycloserine
alr 3840476 c.945A>C synonymous_variant 0.74 cycloserine
alr 3840502 p.Leu307Val missense_variant 0.76 cycloserine
alr 3840503 p.Asn306Thr missense_variant 0.76 cycloserine
alr 3840515 p.Pro302Glu missense_variant 0.72 cycloserine
alr 3840518 c.903G>C synonymous_variant 0.72 cycloserine
alr 3840523 p.Ile300Val missense_variant 0.76 cycloserine
alr 3840527 c.894A>C synonymous_variant 0.74 cycloserine
alr 3840534 p.Gly296Ala missense_variant 0.79 cycloserine
alr 3840542 c.879G>A synonymous_variant 0.81 cycloserine
alr 3840548 c.873G>A synonymous_variant 0.85 cycloserine
alr 3840551 c.870G>T synonymous_variant 0.86 cycloserine
alr 3840554 c.867G>C synonymous_variant 0.84 cycloserine
alr 3840562 p.Ile287Val missense_variant 0.82 cycloserine
alr 3840566 c.855A>G synonymous_variant 0.82 cycloserine
alr 3840574 c.847C>T synonymous_variant 0.84 cycloserine
alr 3840578 c.843T>G synonymous_variant 0.84 cycloserine
alr 3840599 c.822G>C synonymous_variant 0.83 cycloserine
alr 3840605 c.814_816delGTGinsCA frameshift_variant&missense_variant 0.74 cycloserine
alr 3840620 c.801T>C synonymous_variant 0.68 cycloserine
alr 3840624 p.Leu266Arg missense_variant 0.63 cycloserine
alr 3840626 p.Ala265Glu missense_variant 0.6 cycloserine
alr 3840632 c.789A>G synonymous_variant 0.6 cycloserine
alr 3840635 c.786G>C synonymous_variant 0.63 cycloserine
alr 3840638 c.783C>T synonymous_variant 0.6 cycloserine
alr 3840641 c.780A>G synonymous_variant 0.63 cycloserine
alr 3840644 c.777G>C synonymous_variant 0.55 cycloserine
alr 3840647 c.774T>C synonymous_variant 0.55 cycloserine
alr 3840662 c.759G>C synonymous_variant 0.5 cycloserine
alr 3840673 p.Leu250Met missense_variant 0.43 cycloserine
alr 3840680 c.739_741delACGinsGC frameshift_variant&missense_variant 0.42 cycloserine
alr 3840950 c.471G>A synonymous_variant 0.55 cycloserine
alr 3840957 p.Thr155Ser missense_variant 0.55 cycloserine
alr 3840965 c.456G>C synonymous_variant 0.54 cycloserine
alr 3840968 c.453G>C synonymous_variant 0.54 cycloserine
alr 3840971 c.450G>A synonymous_variant 0.54 cycloserine
alr 3840974 c.447C>A synonymous_variant 0.54 cycloserine
alr 3840980 c.441G>T synonymous_variant 0.54 cycloserine
alr 3840989 c.432G>C synonymous_variant 0.58 cycloserine
alr 3840994 p.His143Asp missense_variant 0.59 cycloserine
alr 3840997 c.424T>C synonymous_variant 0.62 cycloserine
alr 3841001 c.420A>G synonymous_variant 0.65 cycloserine
alr 3841013 c.408C>G synonymous_variant 0.71 cycloserine
alr 3841018 p.Leu135Val missense_variant 0.73 cycloserine
alr 3841033 p.Val130Ile missense_variant 0.7 cycloserine
alr 3841036 p.Gln129Glu missense_variant 0.7 cycloserine
alr 3841037 c.384G>C synonymous_variant 0.7 cycloserine
alr 3841055 c.366C>G synonymous_variant 0.67 cycloserine
alr 3841079 c.342T>C synonymous_variant 0.64 cycloserine
alr 3841088 c.333C>T synonymous_variant 0.61 cycloserine
alr 3841100 c.321A>G synonymous_variant 0.59 cycloserine
alr 3841106 c.315T>C synonymous_variant 0.57 cycloserine
alr 3841112 p.Asp103Ala missense_variant 0.56 cycloserine
alr 3841115 c.306T>G synonymous_variant 0.58 cycloserine
alr 3841124 c.297G>A synonymous_variant 0.58 cycloserine
alr 3841127 c.294A>G synonymous_variant 0.58 cycloserine
alr 3841148 c.273C>G synonymous_variant 0.5 cycloserine
alr 3841154 c.267C>G synonymous_variant 0.43 cycloserine
rpoA 3877494 p.Glu338Asp missense_variant 0.55 rifampicin Uncertain significance
rpoA 3877503 c.1005G>C synonymous_variant 0.61 rifampicin
rpoA 3877506 p.Gly334Ala missense_variant 0.61 rifampicin
rpoA 3877515 c.993G>C synonymous_variant 0.65 rifampicin
rpoA 3877557 c.951C>G synonymous_variant 0.69 rifampicin Not assoc w R - Interim
rpoA 3877587 c.921A>C synonymous_variant 0.76 rifampicin
rpoA 3877613 p.Ile299Val missense_variant 0.82 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 0.8 rifampicin
rpoA 3877638 c.870T>G synonymous_variant 0.83 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877677 p.Ala277Ser missense_variant 0.78 rifampicin
rpoA 3877680 c.828G>C synonymous_variant 0.76 rifampicin Not assoc w R - Interim
rpoA 3877685 c.823C>T synonymous_variant 0.76 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 0.78 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 0.79 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3877737 c.771G>C synonymous_variant 0.88 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3877758 c.750G>C synonymous_variant 0.9 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877776 c.732T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877815 c.693C>T synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3877851 c.657C>T synonymous_variant 0.91 rifampicin
rpoA 3877857 c.651G>A synonymous_variant 0.9 rifampicin
rpoA 3877865 c.643C>T synonymous_variant 0.89 rifampicin
rpoA 3877866 c.642G>C synonymous_variant 0.89 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoA 3877887 c.621G>C synonymous_variant 0.88 rifampicin
rpoA 3877900 p.Ser203Thr missense_variant 0.87 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 0.85 rifampicin Not assoc w R - Interim
rpoA 3877908 p.Asn200Ser missense_variant 0.84 rifampicin
rpoA 3877920 c.588G>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
rpoA 3877962 c.546G>T synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3877968 c.540C>G synonymous_variant 0.83 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878001 c.507A>G synonymous_variant 0.83 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.84 rifampicin
rpoA 3878025 c.483C>T synonymous_variant 0.84 rifampicin
rpoA 3878028 c.480G>C synonymous_variant 0.84 rifampicin
rpoA 3878031 c.477T>C synonymous_variant 0.85 rifampicin
rpoA 3878043 c.465G>C synonymous_variant 0.85 rifampicin
rpoA 3878046 c.462T>G synonymous_variant 0.85 rifampicin
rpoA 3878055 c.453A>G synonymous_variant 0.85 rifampicin
rpoA 3878061 c.447G>C synonymous_variant 0.79 rifampicin
rpoA 3878067 c.441C>G synonymous_variant 0.79 rifampicin
rpoA 3878070 c.438T>C synonymous_variant 0.79 rifampicin
rpoA 3878082 c.426T>C synonymous_variant 0.78 rifampicin
rpoA 3878097 c.411G>A synonymous_variant 0.83 rifampicin
rpoA 3878103 c.405A>G synonymous_variant 0.83 rifampicin
rpoA 3878106 c.402G>C synonymous_variant 0.82 rifampicin
rpoA 3878115 c.393G>A synonymous_variant 0.84 rifampicin
rpoA 3878118 c.390T>C synonymous_variant 0.84 rifampicin
rpoA 3878130 c.378C>G synonymous_variant 0.81 rifampicin
rpoA 3878145 c.363C>G synonymous_variant 0.76 rifampicin
rpoA 3878157 c.351C>G synonymous_variant 0.74 rifampicin
rpoA 3878166 c.342C>G synonymous_variant 0.73 rifampicin
rpoA 3878169 c.339G>C synonymous_variant 0.73 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878187 c.321C>G synonymous_variant 0.75 rifampicin
rpoA 3878193 c.315T>C synonymous_variant 0.75 rifampicin Not assoc w R - Interim
rpoA 3878205 c.303T>C synonymous_variant 0.81 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 0.84 rifampicin Not assoc w R - Interim
rpoA 3878229 c.279C>G synonymous_variant 0.88 rifampicin
rpoA 3878247 c.261G>C synonymous_variant 0.87 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 0.88 rifampicin
rpoA 3878264 p.Ser82Gly missense_variant 0.89 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 0.93 rifampicin Uncertain significance
rpoA 3878295 c.213A>G synonymous_variant 0.91 rifampicin
rpoA 3878298 c.210A>G synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878304 c.204G>C synonymous_variant 0.9 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>C synonymous_variant 0.92 rifampicin
rpoA 3878334 c.174T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoA 3878346 c.162T>C synonymous_variant 0.93 rifampicin
rpoA 3878364 c.144A>C synonymous_variant 0.94 rifampicin
rpoA 3878370 c.138T>C synonymous_variant 0.94 rifampicin
rpoA 3878376 c.132G>C synonymous_variant 0.94 rifampicin
rpoA 3878384 c.124C>T synonymous_variant 0.94 rifampicin
rpoA 3878385 c.123C>G synonymous_variant 0.94 rifampicin
rpoA 3878391 c.117T>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoA 3878418 c.90C>T synonymous_variant 0.93 rifampicin
rpoA 3878442 c.66G>C synonymous_variant 0.92 rifampicin
rpoA 3878454 c.54A>G synonymous_variant 0.93 rifampicin
rpoA 3878458 p.Asn17Ser missense_variant 0.93 rifampicin
rpoA 3878471 p.Val13Leu missense_variant 0.91 rifampicin
rpoA 3878472 p.Asp12Glu missense_variant 0.91 rifampicin
rpoA 3878484 c.24C>A synonymous_variant 0.96 rifampicin
rpoA 3878490 c.18C>A synonymous_variant 0.95 rifampicin
rpoA 3878496 c.12A>T synonymous_variant 0.94 rifampicin
rpoA 3878685 c.-178C>T upstream_gene_variant 0.85 rifampicin
rpoA 3878698 c.-191A>G upstream_gene_variant 0.78 rifampicin
rpoA 3878713 c.-206G>C upstream_gene_variant 0.79 rifampicin
rpoA 3878725 c.-218A>G upstream_gene_variant 0.77 rifampicin
rpoA 3878742 c.-235G>A upstream_gene_variant 0.85 rifampicin
rpoA 3878746 c.-239A>G upstream_gene_variant 0.85 rifampicin Uncertain significance
rpoA 3878761 c.-254G>A upstream_gene_variant 0.84 rifampicin Uncertain significance
rpoA 3878764 c.-257A>G upstream_gene_variant 0.84 rifampicin
rpoA 3878776 c.-269G>C upstream_gene_variant 0.82 rifampicin
rpoA 3878779 c.-274_-272delATCinsGT upstream_gene_variant 0.82 rifampicin
rpoA 3878788 c.-281G>T upstream_gene_variant 0.83 rifampicin
rpoA 3878803 c.-296G>C upstream_gene_variant 0.81 rifampicin Uncertain significance
rpoA 3878809 c.-302T>C upstream_gene_variant 0.8 rifampicin
rpoA 3878824 c.-317G>C upstream_gene_variant 0.83 rifampicin
rpoA 3878833 c.-326C>G upstream_gene_variant 0.81 rifampicin
rpoA 3878836 c.-329G>C upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoA 3878842 c.-335G>C upstream_gene_variant 0.82 rifampicin
rpoA 3878853 c.-346G>A upstream_gene_variant 0.82 rifampicin
rpoA 3878869 c.-362G>C upstream_gene_variant 0.83 rifampicin
rpoA 3878878 c.-371T>C upstream_gene_variant 0.84 rifampicin Uncertain significance
rpoA 3878881 c.-374C>G upstream_gene_variant 0.82 rifampicin
rpoA 3878889 c.-382A>G upstream_gene_variant 0.8 rifampicin
rpoA 3878894 c.-387A>G upstream_gene_variant 0.8 rifampicin
rpoA 3878909 c.-402A>C upstream_gene_variant 0.86 rifampicin
rpoA 3878914 c.-407T>C upstream_gene_variant 0.84 rifampicin Uncertain significance
rpoA 3878923 c.-417_-416delGCinsCG upstream_gene_variant 0.86 rifampicin
rpoA 3878947 c.-440G>C upstream_gene_variant 0.82 rifampicin Uncertain significance
rpoA 3878953 c.-446C>G upstream_gene_variant 0.84 rifampicin
rpoA 3878962 c.-455G>A upstream_gene_variant 0.86 rifampicin Uncertain significance
rpoA 3878968 c.-461T>C upstream_gene_variant 0.86 rifampicin Uncertain significance
rpoA 3878974 c.-469_-467delATCinsGG upstream_gene_variant 0.84 rifampicin
rpoA 3878995 c.-488A>G upstream_gene_variant 0.81 rifampicin
rpoA 3878998 c.-491C>G upstream_gene_variant 0.8 rifampicin Uncertain significance
rpoA 3879001 c.-494C>T upstream_gene_variant 0.8 rifampicin
rpoA 3879004 c.-499_-497delAAGinsCGC upstream_gene_variant 0.76 rifampicin
rpoA 3879013 c.-506A>G upstream_gene_variant 0.81 rifampicin
rpoA 3879016 c.-509A>G upstream_gene_variant 0.82 rifampicin
rpoA 3879022 c.-515G>C upstream_gene_variant 0.84 rifampicin
rpoA 3879037 c.-530G>A upstream_gene_variant 0.88 rifampicin
rpoA 3879049 c.-542A>G upstream_gene_variant 0.89 rifampicin
rpoA 3879079 c.-572A>G upstream_gene_variant 0.88 rifampicin
rpoA 3879088 c.-581A>C upstream_gene_variant 0.86 rifampicin
rpoA 3879094 c.-587T>C upstream_gene_variant 0.85 rifampicin
rpoA 3879117 c.-610C>T upstream_gene_variant 0.8 rifampicin
rpoA 3879121 c.-614T>G upstream_gene_variant 0.82 rifampicin
rpoA 3879127 c.-620T>C upstream_gene_variant 0.81 rifampicin
rpoA 3879145 c.-638G>C upstream_gene_variant 0.84 rifampicin
rpoA 3879148 c.-641G>C upstream_gene_variant 0.86 rifampicin
rpoA 3879154 c.-647T>C upstream_gene_variant 0.88 rifampicin
rpoA 3879160 c.-653A>G upstream_gene_variant 0.89 rifampicin
rpoA 3879178 c.-671T>G upstream_gene_variant 0.82 rifampicin
rpoA 3879190 c.-683C>G upstream_gene_variant 0.76 rifampicin
rpoA 3879202 c.-695T>C upstream_gene_variant 0.7 rifampicin
rpoA 3879208 c.-701C>G upstream_gene_variant 0.72 rifampicin
rpoA 3879222 c.-715T>C upstream_gene_variant 0.67 rifampicin
rpoA 3879226 c.-719G>C upstream_gene_variant 0.7 rifampicin
rpoA 3879229 c.-722A>G upstream_gene_variant 0.7 rifampicin
rpoA 3879232 c.-725A>G upstream_gene_variant 0.68 rifampicin
ddn 3986630 c.-214C>G upstream_gene_variant 0.7 delamanid
pretomanid
ddn 3986636 c.-208C>G upstream_gene_variant 0.71 delamanid
pretomanid
ddn 3986648 c.-196C>G upstream_gene_variant 0.65 delamanid
pretomanid
ddn 3986665 c.-179G>C upstream_gene_variant 0.53 delamanid
pretomanid
clpC1 4038271 p.Pro812Ala missense_variant 0.57 pyrazinamide
clpC1 4038272 c.2433T>C synonymous_variant 0.57 pyrazinamide
clpC1 4038278 c.2427T>C synonymous_variant 0.55 pyrazinamide
clpC1 4038281 c.2424C>T synonymous_variant 0.57 pyrazinamide
clpC1 4038287 c.2418C>T synonymous_variant 0.6 pyrazinamide Not assoc w R
clpC1 4038293 c.2412G>C synonymous_variant 0.63 pyrazinamide
clpC1 4038302 p.Thr801Lys missense_variant 0.67 pyrazinamide
clpC1 4038305 c.2400C>G synonymous_variant 0.67 pyrazinamide
clpC1 4038310 p.Val799Leu missense_variant 0.67 pyrazinamide
clpC1 4038314 c.2391T>G synonymous_variant 0.67 pyrazinamide
clpC1 4038317 c.2388G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038320 c.2385G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038329 p.Glu792Asp missense_variant 0.67 pyrazinamide
clpC1 4038338 c.2367C>T synonymous_variant 0.67 pyrazinamide
clpC1 4038347 c.2358G>C synonymous_variant 0.67 pyrazinamide
clpC1 4038356 c.2349T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038359 c.2346A>G synonymous_variant 0.76 pyrazinamide
clpC1 4038368 c.2337T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038388 c.2317T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038398 c.2307G>T synonymous_variant 0.78 pyrazinamide
clpC1 4038403 c.2302T>C synonymous_variant 0.78 pyrazinamide Not assoc w R - Interim
clpC1 4038425 c.2280C>A synonymous_variant 0.78 pyrazinamide
clpC1 4038444 p.Ala754Lys missense_variant 0.85 pyrazinamide
clpC1 4038446 c.2259T>C synonymous_variant 0.85 pyrazinamide
clpC1 4038456 p.Val750Glu missense_variant 0.86 pyrazinamide
clpC1 4038486 p.Gly740Asn missense_variant 0.92 pyrazinamide
clpC1 4038491 c.2214C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038502 p.Ile735Val missense_variant 0.91 pyrazinamide
clpC1 4038508 c.2197C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038518 c.2187G>T synonymous_variant 0.88 pyrazinamide
clpC1 4038530 p.Glu725Asp missense_variant 0.87 pyrazinamide
clpC1 4038537 p.Thr723Ser missense_variant 0.87 pyrazinamide
clpC1 4038539 c.2166G>C synonymous_variant 0.87 pyrazinamide
clpC1 4038569 c.2136C>T synonymous_variant 0.88 pyrazinamide
clpC1 4038575 c.2130C>G synonymous_variant 0.89 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.86 pyrazinamide
clpC1 4038620 c.2085G>A synonymous_variant 0.8 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.8 pyrazinamide
clpC1 4038653 c.2052C>T synonymous_variant 0.82 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.81 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 0.8 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 0.8 pyrazinamide
clpC1 4038668 c.2037G>C synonymous_variant 0.76 pyrazinamide
clpC1 4038671 c.2034T>C synonymous_variant 0.78 pyrazinamide
clpC1 4038677 c.2028G>C synonymous_variant 0.78 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038692 c.2013C>G synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4038695 c.2010C>G synonymous_variant 0.74 pyrazinamide
clpC1 4038698 c.2007C>T synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4038701 c.2004G>C synonymous_variant 0.71 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 0.74 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 0.76 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 0.78 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 0.73 pyrazinamide Not assoc w R - Interim
clpC1 4038773 c.1932T>C synonymous_variant 0.72 pyrazinamide
clpC1 4038782 c.1923G>T synonymous_variant 0.74 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4038809 c.1896G>A synonymous_variant 0.79 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038875 c.1830C>G synonymous_variant 0.86 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.89 pyrazinamide Not assoc w R - Interim
clpC1 4038893 c.1812C>T synonymous_variant 0.89 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.83 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.83 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.82 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 0.78 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 0.79 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 0.78 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4038989 c.1716T>C synonymous_variant 0.81 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4039004 c.1701C>G synonymous_variant 0.8 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 0.79 pyrazinamide
clpC1 4039025 c.1680C>G synonymous_variant 0.78 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039085 c.1620A>G synonymous_variant 0.81 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 0.78 pyrazinamide
clpC1 4039106 c.1599G>T synonymous_variant 0.79 pyrazinamide
clpC1 4039112 c.1593C>A synonymous_variant 0.8 pyrazinamide
clpC1 4039119 c.1585_1586delTCinsAG synonymous_variant 0.76 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 0.75 pyrazinamide
clpC1 4039124 c.1581C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 0.77 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 0.76 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 0.83 pyrazinamide
clpC1 4039172 c.1533A>G synonymous_variant 0.86 pyrazinamide
clpC1 4039178 c.1527G>C synonymous_variant 0.84 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 0.84 pyrazinamide
clpC1 4039190 c.1515C>G synonymous_variant 0.84 pyrazinamide
clpC1 4039193 c.1512C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039223 c.1482C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039226 c.1479T>C synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4039238 c.1467C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039243 c.1462C>T synonymous_variant 0.87 pyrazinamide
clpC1 4039259 c.1446G>A synonymous_variant 0.87 pyrazinamide
clpC1 4039262 c.1443C>T synonymous_variant 0.87 pyrazinamide Not assoc w R - Interim
clpC1 4039268 c.1437C>T synonymous_variant 0.87 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 0.93 pyrazinamide
clpC1 4039304 c.1401G>A synonymous_variant 0.92 pyrazinamide
clpC1 4039313 c.1392C>T synonymous_variant 0.91 pyrazinamide
clpC1 4039319 c.1384_1386delGCTinsAA frameshift_variant&missense_variant 0.9 pyrazinamide
clpC1 4039322 c.1383T>C synonymous_variant 0.88 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 0.9 pyrazinamide
clpC1 4039338 p.Thr456Gln missense_variant 0.88 pyrazinamide
clpC1 4039361 c.1344C>A synonymous_variant 0.86 pyrazinamide
clpC1 4039382 c.1323C>T synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039391 c.1314T>G synonymous_variant 0.84 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039412 c.1293T>A synonymous_variant 0.8 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 0.8 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 0.8 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 0.77 pyrazinamide
clpC1 4039454 c.1251A>G synonymous_variant 0.74 pyrazinamide Not assoc w R - Interim
clpC1 4039463 c.1242C>G synonymous_variant 0.74 pyrazinamide
clpC1 4039466 c.1239T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 0.74 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 0.77 pyrazinamide
clpC1 4039481 c.1224T>G synonymous_variant 0.8 pyrazinamide Not assoc w R - Interim
clpC1 4039484 c.1221T>G synonymous_variant 0.8 pyrazinamide
clpC1 4039508 c.1197G>C synonymous_variant 0.79 pyrazinamide
clpC1 4039526 c.1179G>A synonymous_variant 0.82 pyrazinamide
clpC1 4039532 c.1173C>T synonymous_variant 0.83 pyrazinamide
clpC1 4039553 c.1152C>A synonymous_variant 0.84 pyrazinamide
clpC1 4039562 c.1143C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039565 c.1140G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039576 p.Ala377Ser missense_variant 0.87 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4039583 c.1122C>T synonymous_variant 0.88 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039670 c.1035G>C synonymous_variant 0.93 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039724 c.981A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.87 pyrazinamide
clpC1 4039739 c.966C>G synonymous_variant 0.85 pyrazinamide
clpC1 4039742 c.963C>T synonymous_variant 0.85 pyrazinamide
clpC1 4039748 c.957G>A synonymous_variant 0.87 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 0.87 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 0.87 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039775 c.930G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 0.88 pyrazinamide
clpC1 4039781 c.924G>C synonymous_variant 0.88 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.88 pyrazinamide
clpC1 4039796 c.909C>T synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4039805 c.900C>G synonymous_variant 0.86 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 0.82 pyrazinamide
clpC1 4039820 c.885T>C synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4039826 c.879C>G synonymous_variant 0.88 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 0.87 pyrazinamide
clpC1 4039832 c.873C>T synonymous_variant 0.89 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 0.89 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 0.89 pyrazinamide
clpC1 4039931 c.774T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039937 c.768G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039943 c.762G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 0.86 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 0.86 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 0.86 pyrazinamide
clpC1 4039955 c.750G>T synonymous_variant 0.84 pyrazinamide
clpC1 4039958 c.747G>C synonymous_variant 0.83 pyrazinamide
clpC1 4039964 c.741C>T synonymous_variant 0.81 pyrazinamide
clpC1 4040000 c.705C>T synonymous_variant 0.84 pyrazinamide
clpC1 4040015 c.690G>A synonymous_variant 0.84 pyrazinamide Not assoc w R - Interim
clpC1 4040021 c.684A>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 0.84 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 0.83 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.81 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040105 c.600C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 0.86 pyrazinamide Not assoc w R - Interim
clpC1 4040162 c.543G>C synonymous_variant 0.85 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 0.84 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040195 c.510G>T synonymous_variant 0.83 pyrazinamide
clpC1 4040200 c.505T>C synonymous_variant 0.82 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 0.82 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040207 c.498T>C synonymous_variant 0.82 pyrazinamide
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.88 pyrazinamide
clpC1 4040225 c.480A>C synonymous_variant 0.97 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 0.97 pyrazinamide
clpC1 4040231 c.474C>T synonymous_variant 0.94 pyrazinamide
clpC1 4040246 c.459C>G synonymous_variant 0.97 pyrazinamide
clpC1 4040249 c.456A>G synonymous_variant 0.95 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 0.9 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 0.88 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 0.85 pyrazinamide
clpC1 4040309 c.396C>T synonymous_variant 0.88 pyrazinamide
clpC1 4040342 c.363C>G synonymous_variant 0.8 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 0.79 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.79 pyrazinamide
clpC1 4040363 c.342A>C synonymous_variant 0.79 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.79 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.75 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.78 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.77 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.76 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4040419 c.286C>T synonymous_variant 0.65 pyrazinamide
clpC1 4040423 c.282A>G synonymous_variant 0.64 pyrazinamide Not assoc w R - Interim
clpC1 4040426 c.279T>C synonymous_variant 0.64 pyrazinamide
clpC1 4040431 c.274T>C synonymous_variant 0.72 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.7 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.68 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.66 pyrazinamide
clpC1 4040462 c.243C>T synonymous_variant 0.64 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.64 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.67 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>C synonymous_variant 0.71 pyrazinamide Not assoc w R - Interim
clpC1 4040486 c.219G>C synonymous_variant 0.8 pyrazinamide
clpC1 4040495 c.210C>A synonymous_variant 0.82 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040525 c.180C>T synonymous_variant 0.82 pyrazinamide Not assoc w R - Interim
clpC1 4040528 c.177G>C synonymous_variant 0.82 pyrazinamide
clpC1 4040531 c.174T>C synonymous_variant 0.82 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040537 c.168G>C synonymous_variant 0.79 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.81 pyrazinamide Not assoc w R - Interim
clpC1 4040561 c.144A>G synonymous_variant 0.84 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.83 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.82 pyrazinamide
clpC1 4040582 c.123G>C synonymous_variant 0.79 pyrazinamide Not assoc w R - Interim
clpC1 4040588 c.117T>C synonymous_variant 0.75 pyrazinamide
clpC1 4040591 c.114C>T synonymous_variant 0.75 pyrazinamide
clpC1 4040597 c.108C>T synonymous_variant 0.75 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCG frameshift_variant&missense_variant 0.75 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.73 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.73 pyrazinamide
clpC1 4040654 c.51G>A synonymous_variant 0.5 pyrazinamide
clpC1 4040657 c.48T>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040662 c.43C>T synonymous_variant 0.48 pyrazinamide Not assoc w R - Interim
clpC1 4040669 c.36C>G synonymous_variant 0.48 pyrazinamide
clpC1 4040675 c.30C>G synonymous_variant 0.5 pyrazinamide Not assoc w R - Interim
clpC1 4040695 c.10C>A synonymous_variant 0.45 pyrazinamide
panD 4044150 c.132A>G synonymous_variant 0.62 pyrazinamide
panD 4044156 c.126A>G synonymous_variant 0.62 pyrazinamide Not assoc w R - Interim
panD 4044159 c.123C>T synonymous_variant 0.59 pyrazinamide
panD 4044165 c.117G>A synonymous_variant 0.59 pyrazinamide
panD 4044177 c.105C>G synonymous_variant 0.65 pyrazinamide Not assoc w R - Interim
panD 4044180 c.102C>T synonymous_variant 0.67 pyrazinamide
panD 4044188 c.94T>C synonymous_variant 0.71 pyrazinamide
panD 4044195 c.87T>C synonymous_variant 0.71 pyrazinamide
panD 4044225 c.57C>T synonymous_variant 0.73 pyrazinamide
panD 4044231 p.Cys17Gln missense_variant 0.62 pyrazinamide
panD 4044237 c.45G>C synonymous_variant 0.62 pyrazinamide
panD 4044264 c.18G>C synonymous_variant 0.58 pyrazinamide
panD 4044881 c.-600T>C upstream_gene_variant 0.78 pyrazinamide
panD 4044895 c.-614A>G upstream_gene_variant 0.74 pyrazinamide
panD 4044896 c.-615T>C upstream_gene_variant 0.74 pyrazinamide
panD 4044899 c.-618A>G upstream_gene_variant 0.74 pyrazinamide
panD 4044902 c.-623_-621delACGinsGC upstream_gene_variant 0.78 pyrazinamide
panD 4044908 c.-628_-627delCTinsTG upstream_gene_variant 0.74 pyrazinamide
panD 4044914 c.-633A>G upstream_gene_variant 0.74 pyrazinamide
panD 4044917 c.-636G>C upstream_gene_variant 0.7 pyrazinamide
panD 4044923 c.-642A>G upstream_gene_variant 0.65 pyrazinamide
panD 4044927 c.-646C>G upstream_gene_variant 0.67 pyrazinamide
panD 4044929 c.-648G>C upstream_gene_variant 0.67 pyrazinamide
panD 4044935 c.-655_-654delAAinsTG upstream_gene_variant 0.64 pyrazinamide
panD 4044953 c.-673_-672delCGinsTT upstream_gene_variant 0.71 pyrazinamide
panD 4044956 c.-675C>G upstream_gene_variant 0.71 pyrazinamide
panD 4044962 c.-681C>G upstream_gene_variant 0.64 pyrazinamide
panD 4044965 c.-684T>C upstream_gene_variant 0.74 pyrazinamide
panD 4044977 c.-696T>C upstream_gene_variant 0.76 pyrazinamide
panD 4045000 c.-719A>T upstream_gene_variant 0.74 pyrazinamide
panD 4045001 c.-720G>C upstream_gene_variant 0.69 pyrazinamide
panD 4045022 c.-742_-741delTCinsCG upstream_gene_variant 0.52 pyrazinamide
panD 4045028 c.-747C>G upstream_gene_variant 0.5 pyrazinamide
panD 4045034 c.-753A>G upstream_gene_variant 0.52 pyrazinamide
panD 4045052 c.-771G>C upstream_gene_variant 0.46 pyrazinamide
panD 4045063 c.-782T>C upstream_gene_variant 0.44 pyrazinamide
panD 4045067 c.-786C>G upstream_gene_variant 0.46 pyrazinamide
panD 4045070 c.-789C>T upstream_gene_variant 0.46 pyrazinamide
panD 4045073 c.-792C>G upstream_gene_variant 0.46 pyrazinamide
panD 4045076 c.-795A>C upstream_gene_variant 0.46 pyrazinamide
panD 4045088 c.-807T>G upstream_gene_variant 0.43 pyrazinamide
panD 4045094 c.-813T>G upstream_gene_variant 0.35 pyrazinamide
panD 4045097 c.-816T>G upstream_gene_variant 0.35 pyrazinamide
panD 4045105 c.-824T>C upstream_gene_variant 0.35 pyrazinamide
glpK 4138280 c.1474_1476delGACinsAT frameshift_variant&synonymous_variant 0.59 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138288 p.Thr490Ala missense_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138292 c.1464A>G synonymous_variant 0.62 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138301 c.1455G>A synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138307 c.1449G>A synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138310 p.Arg482Gln missense_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138316 c.1440C>T synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138331 c.1425C>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138338 p.Ala473Asp missense_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138340 c.1416G>C synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138352 c.1404C>G synonymous_variant 0.62 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138360 c.1396T>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138370 c.1386C>T synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138376 p.Val460Ala missense_variant 0.5 ethambutol Not assoc w R
moxifloxacin Not assoc w R
streptomycin Not assoc w R
levofloxacin Not assoc w R
rifampicin Not assoc w R
isoniazid Not assoc w R
glpK 4138379 c.1377T>C synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138382 c.1374A>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138385 c.1371A>G synonymous_variant 0.52 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138397 c.1359C>G synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138418 c.1338T>C synonymous_variant 0.63 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138427 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.48 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138433 c.1323C>T synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138442 c.1314C>T synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138451 c.1305T>C synonymous_variant 0.45 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138457 p.Asp433Glu missense_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138472 c.1284G>T synonymous_variant 0.45 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138478 c.1278T>C synonymous_variant 0.43 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138481 c.1275G>T synonymous_variant 0.43 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138490 c.1266G>T synonymous_variant 0.41 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138493 c.1261_1263delCAGinsGA frameshift_variant&missense_variant 0.41 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138496 c.1260G>T synonymous_variant 0.42 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138502 c.1254T>G synonymous_variant 0.5 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138511 c.1245C>T synonymous_variant 0.58 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138514 c.1242A>C synonymous_variant 0.58 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138517 c.1239A>G synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138529 c.1227G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138535 c.1221T>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138550 c.1206C>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138568 c.1188A>C synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138574 c.1182G>T synonymous_variant 0.73 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138580 c.1176C>T synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138583 c.1173G>C synonymous_variant 0.74 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138596 p.Phe387Tyr missense_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138598 c.1158G>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138631 c.1125C>G synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138640 c.1116C>T synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 0.83 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 0.84 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>G synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138702 p.Gln352Glu missense_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>T synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138706 c.1050C>G synonymous_variant 0.8 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138714 p.Ala348Ser missense_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138715 c.1041G>A synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138751 c.1005T>C synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.999A>G synonymous_variant 0.82 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139120 p.Asp212Glu missense_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139132 c.624A>C synonymous_variant 0.74 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139143 c.613T>C synonymous_variant 0.72 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139150 c.606G>C synonymous_variant 0.69 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139156 c.600C>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139165 c.591A>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139168 c.588T>C synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139176 p.Val194Ile missense_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139177 c.579T>C synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139183 c.573T>G synonymous_variant 0.77 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139186 c.570G>C synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139215 c.541T>C synonymous_variant 0.83 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139223 p.Thr178Ser missense_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139230 p.Pro176Ala missense_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139231 c.525A>C synonymous_variant 0.81 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139243 c.513A>G synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139249 c.507C>T synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139255 c.501G>A synonymous_variant 0.79 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139261 c.495C>G synonymous_variant 0.79 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139270 c.486C>G synonymous_variant 0.71 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139273 c.483A>G synonymous_variant 0.7 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139276 c.480T>C synonymous_variant 0.61 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139282 c.474T>C synonymous_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139285 c.469_471delGAAinsCG frameshift_variant&missense_variant 0.63 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139297 c.459G>A synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139302 c.454C>T synonymous_variant 0.67 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139312 c.444T>C synonymous_variant 0.65 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139601 p.Arg52Gln missense_variant 0.6 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139609 c.145_147delATCinsGG frameshift_variant&missense_variant 0.57 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4139630 c.126C>T synonymous_variant 0.59 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139633 c.123C>G synonymous_variant 0.57 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139648 c.108T>C synonymous_variant 0.54 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139652 p.His35Gly missense_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139657 c.99T>C synonymous_variant 0.55 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
embC 4240525 c.663C>G synonymous_variant 0.54 ethambutol
embC 4240657 c.795G>C synonymous_variant 0.43 ethambutol
embC 4240660 c.798C>G synonymous_variant 0.53 ethambutol
embC 4240671 p.Thr270Ile missense_variant 0.55 ethambutol Not assoc w R
embC 4240678 c.816T>C synonymous_variant 0.53 ethambutol
embC 4240681 c.819G>C synonymous_variant 0.53 ethambutol
embC 4240685 p.Thr275Ala missense_variant 0.59 ethambutol
embC 4240690 c.828G>C synonymous_variant 0.56 ethambutol
embC 4240693 c.831T>C synonymous_variant 0.56 ethambutol
embC 4240698 p.Ala279Gly missense_variant 0.56 ethambutol
embC 4240726 c.864G>C synonymous_variant 0.71 ethambutol Not assoc w R - Interim
embC 4240729 c.867C>G synonymous_variant 0.71 ethambutol
embC 4240747 c.885C>T synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embC 4240759 c.897C>G synonymous_variant 0.81 ethambutol
embC 4240765 c.903C>G synonymous_variant 0.8 ethambutol
embC 4240783 c.921G>C synonymous_variant 0.87 ethambutol
embC 4240789 c.927T>C synonymous_variant 0.93 ethambutol
embC 4240795 c.933C>G synonymous_variant 0.93 ethambutol
embC 4241185 c.1323G>C synonymous_variant 0.68 ethambutol
embC 4241188 c.1326C>T synonymous_variant 0.71 ethambutol
embC 4241194 c.1332C>G synonymous_variant 0.74 ethambutol
embC 4241197 c.1335G>C synonymous_variant 0.74 ethambutol
embC 4241200 c.1338C>T synonymous_variant 0.74 ethambutol
embC 4241203 c.1341T>C synonymous_variant 0.74 ethambutol
embC 4241206 c.1344G>C synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embC 4241221 c.1359C>T synonymous_variant 0.76 ethambutol
embC 4241224 c.1362G>A synonymous_variant 0.68 ethambutol
embC 4241230 c.1368A>G synonymous_variant 0.67 ethambutol
embC 4241233 c.1371G>C synonymous_variant 0.65 ethambutol
embC 4241236 c.1374C>G synonymous_variant 0.69 ethambutol
embC 4241239 c.1377C>T synonymous_variant 0.65 ethambutol
embC 4241240 c.1378_1380delCTGinsAT frameshift_variant&missense_variant 0.65 ethambutol
embC 4241248 c.1386G>C synonymous_variant 0.65 ethambutol
embC 4241251 c.1389T>C synonymous_variant 0.65 ethambutol
embC 4241255 c.1393A>C synonymous_variant 0.65 ethambutol
embC 4241259 p.Arg466Gln missense_variant 0.61 ethambutol Uncertain significance
embC 4241266 c.1404C>G synonymous_variant 0.65 ethambutol
embC 4241272 c.1410A>G synonymous_variant 0.61 ethambutol
embC 4241275 c.1413A>G synonymous_variant 0.61 ethambutol
embC 4241279 p.Val473Leu missense_variant 0.61 ethambutol
embC 4241284 c.1422G>A synonymous_variant 0.61 ethambutol
embA 4245041 c.1809C>G synonymous_variant 0.41 ethambutol
embA 4245056 c.1824C>G synonymous_variant 0.47 ethambutol
embA 4245060 c.1828T>C synonymous_variant 0.5 ethambutol
embA 4245063 c.1831C>T synonymous_variant 0.5 ethambutol
embA 4245078 p.Trp616Val missense_variant 0.47 ethambutol
embA 4245083 c.1851A>C synonymous_variant 0.5 ethambutol
embA 4245089 c.1857G>C synonymous_variant 0.57 ethambutol
embA 4245093 p.Ile621Val missense_variant 0.53 ethambutol Uncertain significance
embA 4245101 c.1869G>C synonymous_variant 0.61 ethambutol
embA 4245125 c.1893G>C synonymous_variant 0.79 ethambutol
embA 4245137 c.1905T>C synonymous_variant 0.79 ethambutol
embA 4245149 c.1917C>G synonymous_variant 0.83 ethambutol
embA 4245182 c.1950T>C synonymous_variant 0.77 ethambutol
embA 4245183 c.1951C>T synonymous_variant 0.76 ethambutol
embA 4245186 p.Thr652Ala missense_variant 0.76 ethambutol
embA 4245189 c.1957C>T synonymous_variant 0.76 ethambutol
embA 4245198 p.Leu656Ala missense_variant 0.76 ethambutol
embA 4245206 c.1974A>C synonymous_variant 0.76 ethambutol
embA 4245207 c.1975T>C synonymous_variant 0.76 ethambutol
embA 4245215 c.1983A>C synonymous_variant 0.76 ethambutol
embA 4245222 p.Tyr664Leu missense_variant 0.72 ethambutol
embA 4245245 c.2013C>G synonymous_variant 0.81 ethambutol
embA 4245257 c.2025A>G synonymous_variant 0.67 ethambutol
embA 4245258 p.Val676Ile missense_variant 0.63 ethambutol Uncertain significance
embA 4245263 c.2031A>G synonymous_variant 0.63 ethambutol Not assoc w R - Interim
embA 4245266 p.Asp678Glu missense_variant 0.6 ethambutol
embA 4245268 p.Asn679Ser missense_variant 0.6 ethambutol
embA 4245285 c.2053T>C synonymous_variant 0.53 ethambutol
embA 4245453 p.Ala741Thr missense_variant 0.53 ethambutol
embA 4245461 c.2229C>A synonymous_variant 0.56 ethambutol
embA 4245471 p.Ala747Leu missense_variant 0.53 ethambutol
embA 4245477 p.Met749Leu missense_variant 0.5 ethambutol
embA 4245497 c.2265C>G synonymous_variant 0.53 ethambutol
embA 4245501 p.Ala757Thr missense_variant 0.53 ethambutol
embB 4246253 c.-261C>T upstream_gene_variant 0.5 ethambutol
embA 4246277 c.3045G>A synonymous_variant 0.56 ethambutol Not assoc w R - Interim
embA 4246278 p.Ala1016Ser missense_variant 0.56 ethambutol Uncertain significance
embA 4246290 p.Leu1020Gly missense_variant 0.5 ethambutol
embA 4246296 p.Gln1022Glu missense_variant 0.5 ethambutol
embA 4246299 p.Ser1023Ala missense_variant 0.53 ethambutol
embA 4246302 p.Ser1024Gly missense_variant 0.53 ethambutol
embA 4246305 p.Ser1025Glu missense_variant 0.53 ethambutol
embA 4246308 c.3076_3078delACCinsGG frameshift_variant&missense_variant 0.59 ethambutol Uncertain significance
embB 4246316 c.-198T>C upstream_gene_variant 0.56 ethambutol
embA 4246335 p.Ala1035Thr missense_variant 0.5 ethambutol
embB 4246338 c.-176C>T upstream_gene_variant 0.45 ethambutol
embA 4246341 c.3109_3111delCTGinsTA frameshift_variant&stop_gained 0.45 ethambutol Uncertain significance
embB 4246355 c.-159G>C upstream_gene_variant 0.45 ethambutol
embA 4246359 c.3127_3129delGCCinsTG frameshift_variant&missense_variant 0.45 ethambutol Uncertain significance
embB 4246364 c.-150G>C upstream_gene_variant 0.45 ethambutol
embB 4246368 c.-146C>T upstream_gene_variant 0.43 ethambutol
embB 4246373 c.-141T>C upstream_gene_variant 0.4 ethambutol
embB 4246376 c.-138G>C upstream_gene_variant 0.4 ethambutol
embB 4247425 c.912G>C synonymous_variant 0.37 ethambutol
embB 4247437 c.924A>G synonymous_variant 0.47 ethambutol Not assoc w R - Interim
embB 4247452 c.939C>G synonymous_variant 0.54 ethambutol
embB 4247470 c.957T>C synonymous_variant 0.66 ethambutol
embB 4247497 c.984T>C synonymous_variant 0.72 ethambutol
embB 4247500 c.987C>G synonymous_variant 0.72 ethambutol
embB 4247506 c.993C>G synonymous_variant 0.71 ethambutol
embB 4247512 c.999T>C synonymous_variant 0.7 ethambutol
embB 4247527 c.1014G>C synonymous_variant 0.74 ethambutol
embB 4247539 c.1026T>C synonymous_variant 0.73 ethambutol
embB 4247550 p.Ala346Asp missense_variant 0.74 ethambutol
embB 4247554 c.1041T>C synonymous_variant 0.76 ethambutol
embB 4247566 c.1053C>G synonymous_variant 0.78 ethambutol
embB 4247572 c.1059A>C synonymous_variant 0.76 ethambutol
embB 4247590 c.1077A>G synonymous_variant 0.78 ethambutol Not assoc w R - Interim
embB 4247629 c.1116C>G synonymous_variant 0.69 ethambutol
embB 4247632 c.1119C>G synonymous_variant 0.68 ethambutol
embB 4247638 c.1125G>C synonymous_variant 0.59 ethambutol
embB 4247645 p.Glu378Thr missense_variant 0.5 ethambutol
embB 4247648 c.1135_1137delGCCinsTG frameshift_variant&missense_variant 0.5 ethambutol
embB 4247656 c.1143A>G synonymous_variant 0.5 ethambutol
embB 4247657 p.Pro382Ala missense_variant 0.5 ethambutol
embB 4247662 c.1149C>G synonymous_variant 0.55 ethambutol
embB 4247677 c.1164C>G synonymous_variant 0.57 ethambutol Not assoc w R - Interim
embB 4247684 c.1171T>C synonymous_variant 0.6 ethambutol
embB 4247983 c.1470G>C synonymous_variant 0.52 ethambutol
embB 4248007 c.1494C>A synonymous_variant 0.62 ethambutol
embB 4248035 p.Val508Ile missense_variant 0.62 ethambutol
embB 4248041 p.Ala510Thr missense_variant 0.65 ethambutol Uncertain significance
embB 4248044 p.Lys511Ala missense_variant 0.65 ethambutol
embB 4248055 c.1542G>C synonymous_variant 0.67 ethambutol
embB 4248064 c.1551G>C synonymous_variant 0.63 ethambutol Not assoc w R - Interim
embB 4248070 c.1557T>C synonymous_variant 0.63 ethambutol
embB 4248085 c.1572T>C synonymous_variant 0.72 ethambutol
embB 4248097 c.1584C>G synonymous_variant 0.74 ethambutol
embB 4248118 c.1605T>G synonymous_variant 0.72 ethambutol
embB 4248127 c.1614G>C synonymous_variant 0.74 ethambutol
embB 4248130 c.1617G>C synonymous_variant 0.69 ethambutol
embB 4248133 c.1620C>A synonymous_variant 0.68 ethambutol
embB 4248139 c.1626C>G synonymous_variant 0.69 ethambutol
embB 4248142 c.1629T>C synonymous_variant 0.71 ethambutol
embB 4248143 c.1630T>C synonymous_variant 0.71 ethambutol
embB 4248146 c.1633_1635delATCinsCG frameshift_variant&missense_variant 0.71 ethambutol
embB 4248149 p.Thr546Ser missense_variant 0.71 ethambutol
embB 4248157 c.1644A>G synonymous_variant 0.76 ethambutol Not assoc w R - Interim
embB 4248161 c.1648C>T synonymous_variant 0.74 ethambutol Not assoc w R - Interim
embB 4248169 c.1656C>G synonymous_variant 0.78 ethambutol
embB 4248190 c.1677G>C synonymous_variant 0.81 ethambutol Not assoc w R - Interim
embB 4248200 p.Ile563Val missense_variant 0.82 ethambutol
embB 4248206 p.Ser565Gly missense_variant 0.84 ethambutol Uncertain significance
embB 4248211 c.1698G>A synonymous_variant 0.84 ethambutol
embB 4248220 c.1707A>C synonymous_variant 0.83 ethambutol
embB 4248241 c.1728C>T synonymous_variant 0.82 ethambutol
embB 4248277 c.1764G>C synonymous_variant 0.79 ethambutol
embB 4248298 c.1785C>T synonymous_variant 0.71 ethambutol
embB 4248304 c.1791G>C synonymous_variant 0.68 ethambutol
embB 4248316 c.1803C>G synonymous_variant 0.57 ethambutol
aftB 4268123 c.712_714delAGTinsGC frameshift_variant&synonymous_variant 0.63 ethambutol Uncertain significance
aftB 4268126 c.711G>C synonymous_variant 0.63 ethambutol
aftB 4268129 c.708T>G synonymous_variant 0.61 ethambutol
aftB 4268132 c.705G>C synonymous_variant 0.61 ethambutol
aftB 4268138 c.699A>G synonymous_variant 0.58 ethambutol
aftB 4268144 c.693T>C synonymous_variant 0.64 ethambutol
aftB 4268168 p.Ala223Gly missense_variant 0.68 ethambutol
aftB 4268177 c.658_660delTTGinsCT frameshift_variant&missense_variant 0.65 ethambutol Uncertain significance
aftB 4268180 c.655_657delTTCinsCG frameshift_variant&missense_variant 0.65 ethambutol Uncertain significance
aftB 4268194 p.Leu215Val missense_variant 0.67 ethambutol
aftB 4268206 p.Val211Leu missense_variant 0.65 ethambutol
aftB 4268207 c.630C>G synonymous_variant 0.65 ethambutol
aftB 4268213 c.624T>C synonymous_variant 0.67 ethambutol
aftB 4268222 c.615G>A synonymous_variant 0.56 ethambutol
aftB 4268225 c.612G>C synonymous_variant 0.55 ethambutol
aftB 4268228 c.609C>G synonymous_variant 0.55 ethambutol
aftB 4268231 p.Ile202Thr missense_variant 0.55 ethambutol
aftB 4268236 c.601T>C synonymous_variant 0.5 ethambutol
aftB 4268255 c.582G>C synonymous_variant 0.48 ethambutol
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 capreomycin Not assoc w R
amikacin Not assoc w R
kanamycin Not assoc w R