Run ID: ERR323033
Sample name:
Date: 2024-05-17T14:14:45.436004
Number of reads: 1219331
Percentage reads mapped: 22.93
Median coverage: 19.0
Strain: La3;M.canetti;lineage2.1;lineage4.9
Spoligotype:
Drug-resistance: MDR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage6.1.3 | West-Africa 2 | RD702 | 0.12 |
lineage2.1 | East-Asian (non-Beijing) | None | 0.22 |
lineage1.1.1 | Indo-Oceanic | RD239 | 0.07 |
lineage6.2.3 | West-Africa 2 | RD702 | 0.17 |
lineage4.9 | Euro-American (H37Rv-like) | None | 0.85 |
La3 | M.orygis | None | 0.3 |
M.canetti | M.canetti | None | 0.25 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | katG | p.Ile335Thr | Mutation from literature | |
c.949_951delATCinsCG | Assoc w R | High-level resistance | ||
c.496_498delGTTinsAC | Assoc w R | High-level resistance | ||
c.300_301delGC | Assoc w R | High-level resistance | ||
c.296_297insTG | Assoc w R | High-level resistance | ||
ethambutol | embB | p.His312Arg | Mutation from literature | |
p.Tyr384Asn | Mutation from literature | |||
p.Ala388Gly | Mutation from literature | |||
p.Asn399Asp | Mutation from literature | |||
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | tlyA | c.-2_1delGCGinsCGGA | Assoc w R | |
c.4_6delGCAinsTT | Assoc w R | |||
kanamycin | ||||
cycloserine | ||||
ethionamide | ethA | c.478_480delCCGinsAC | Assoc w R | |
c.460_462delTCGinsGC | Assoc w R | |||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fgd1 | c.730_732delAACinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
c.838_840delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
fbiC | c.550_552delCAAinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |
c.604_606delTCGinsGC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.859_861delATCinsGG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1039_1041delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.1948_1950delCGCinsAG | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
c.2401_2403delGAAinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance | ||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
fgd1 | 491512 | c.730_732delAACinsGG | frameshift_variant&missense_variant | 0.98 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fgd1 | 491620 | c.838_840delATCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
fbiC | 1303480 | c.550_552delCAAinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303534 | c.604_606delTCGinsGC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303789 | c.859_861delATCinsGG | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1303969 | c.1039_1041delGTTinsAC | frameshift_variant&missense_variant | 1.0 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1304878 | c.1948_1950delCGCinsAG | frameshift_variant&missense_variant | 0.94 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
fbiC | 1305331 | c.2401_2403delGAAinsAC | frameshift_variant&missense_variant | 0.96 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 1.0 | streptomycin | Uncertain significance | Mutation from literature |
tlyA | 1917938 | c.-2_1delGCGinsCGGA | frameshift_variant&synonymous_variant | 1.0 | capreomycin | Assoc w R | |
tlyA | 1917943 | c.4_6delGCAinsTT | frameshift_variant&missense_variant | 1.0 | capreomycin | Assoc w R | |
katG | 2155108 | p.Ile335Thr | missense_variant | 1.0 | isoniazid | Mutation from literature | |
katG | 2155161 | c.949_951delATCinsCG | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
katG | 2155614 | c.496_498delGTTinsAC | frameshift_variant&missense_variant | 1.0 | isoniazid | Assoc w R | High-level resistance |
katG | 2155810 | c.300_301delGC | frameshift_variant | 0.95 | isoniazid | Assoc w R | High-level resistance |
katG | 2155815 | c.296_297insTG | frameshift_variant | 0.95 | isoniazid | Assoc w R | High-level resistance |
embB | 4247448 | p.His312Arg | missense_variant | 1.0 | ethambutol | Mutation from literature | |
embB | 4247663 | p.Tyr384Asn | missense_variant | 1.0 | ethambutol | Mutation from literature | |
embB | 4247676 | p.Ala388Gly | missense_variant | 1.0 | ethambutol | Mutation from literature | |
embB | 4247708 | p.Asn399Asp | missense_variant | 1.0 | ethambutol | Mutation from literature | |
ethA | 4326994 | c.478_480delCCGinsAC | frameshift_variant&missense_variant | 1.0 | ethionamide | Assoc w R | |
ethA | 4327012 | c.460_462delTCGinsGC | frameshift_variant&missense_variant | 1.0 | ethionamide | Assoc w R |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 498 | c.498C>G | synonymous_variant | 0.9 | isoniazid | |
dnaA | 504 | c.504T>C | synonymous_variant | 0.95 | isoniazid | |
dnaA | 510 | c.510T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 522 | c.522T>C | synonymous_variant | 0.98 | isoniazid | Not assoc w R - Interim |
dnaA | 525 | c.525T>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 534 | c.534T>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 540 | c.540C>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 543 | c.543C>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 571 | c.571T>C | synonymous_variant | 0.99 | isoniazid | |
dnaA | 576 | c.576G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 582 | c.582A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 591 | c.591C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 600 | c.600T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 609 | c.609C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 610 | c.610C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 636 | c.636C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 645 | c.645A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 654 | c.654A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 660 | c.660G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 663 | c.663A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 669 | c.669C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 672 | c.672T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 675 | c.675C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 678 | c.678A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 682 | c.682_684delTTGinsCC | frameshift_variant&missense_variant | 1.0 | isoniazid | Uncertain significance |
dnaA | 690 | c.690G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 693 | c.693A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 705 | c.705A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.98 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.98 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.98 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.96 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.97 | isoniazid | |
dnaA | 843 | c.843T>C | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 846 | c.846T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 876 | c.876C>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 877 | c.877T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 909 | c.909A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 912 | c.912T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 918 | c.918C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 921 | c.921A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 927 | c.927G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 933 | c.933C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 942 | c.942C>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 945 | c.945G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 955 | c.955A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 963 | c.963C>G | synonymous_variant | 0.93 | isoniazid | |
dnaA | 966 | c.966T>C | synonymous_variant | 0.93 | isoniazid | |
dnaA | 975 | c.975G>C | synonymous_variant | 0.93 | isoniazid | |
dnaA | 984 | c.984T>C | synonymous_variant | 0.85 | isoniazid | Not assoc w R - Interim |
dnaA | 990 | c.990A>G | synonymous_variant | 0.8 | isoniazid | Not assoc w R - Interim |
dnaA | 993 | c.993A>G | synonymous_variant | 0.8 | isoniazid | |
dnaA | 996 | c.996A>C | synonymous_variant | 0.8 | isoniazid | Not assoc w R - Interim |
dnaA | 1002 | c.1002G>A | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1005 | c.1005G>C | synonymous_variant | 0.8 | isoniazid | |
dnaA | 1008 | c.1008G>A | synonymous_variant | 0.8 | isoniazid | Not assoc w R - Interim |
dnaA | 1020 | c.1020C>G | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1024 | c.1024T>C | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1035 | c.1035A>G | synonymous_variant | 0.88 | isoniazid | |
dnaA | 1047 | c.1047A>G | synonymous_variant | 0.88 | isoniazid | |
dnaA | 1050 | c.1050G>C | synonymous_variant | 0.89 | isoniazid | |
dnaA | 1053 | c.1053C>G | synonymous_variant | 0.9 | isoniazid | Not assoc w R - Interim |
dnaA | 1059 | c.1059C>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1068 | c.1068T>C | synonymous_variant | 0.94 | isoniazid | |
dnaA | 1071 | c.1071C>G | synonymous_variant | 0.94 | isoniazid | |
dnaA | 1074 | c.1074C>G | synonymous_variant | 0.91 | isoniazid | |
dnaA | 1092 | c.1092T>C | synonymous_variant | 0.96 | isoniazid | Not assoc w R - Interim |
dnaA | 1098 | c.1098A>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1104 | c.1104T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1110 | c.1110T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1122 | c.1122C>A | synonymous_variant | 0.97 | isoniazid | Not assoc w R - Interim |
dnaA | 1125 | c.1125G>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.99 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.99 | isoniazid | Not assoc w R - Interim |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1177 | p.Ala393Ser | missense_variant | 1.0 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1197 | c.1197T>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1204 | c.1204C>T | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 1.0 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1293 | c.1293T>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1302 | c.1302C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1317 | c.1317A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1329 | c.1329A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1332 | c.1332A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1335 | c.1335G>A | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1338 | c.1338T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1353 | c.1353T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1356 | c.1356T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
dnaA | 1365 | c.1365C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1371 | c.1371T>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1375 | c.1375T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1383 | c.1383A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1389 | c.1389C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1392 | c.1392A>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1395 | c.1395G>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1404 | c.1404T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1407 | c.1407T>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1416 | c.1416C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1419 | c.1419C>G | synonymous_variant | 1.0 | isoniazid | |
dnaA | 1431 | c.1431A>G | synonymous_variant | 0.98 | isoniazid | |
dnaA | 1461 | c.1461C>A | synonymous_variant | 0.97 | isoniazid | |
dnaA | 1464 | c.1464T>C | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1470 | c.1470C>G | synonymous_variant | 0.96 | isoniazid | |
dnaA | 1473 | c.1473T>C | synonymous_variant | 0.96 | isoniazid | Not assoc w R - Interim |
dnaA | 1485 | c.1485A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1488 | c.1488A>G | synonymous_variant | 0.95 | isoniazid | |
dnaA | 1503 | c.1503C>T | synonymous_variant | 0.93 | isoniazid | |
gyrB | 5782 | c.543A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5788 | c.549G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5791 | c.552A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5806 | c.567C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5809 | c.570C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5815 | c.576C>A | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5824 | c.585A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5827 | c.588G>A | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5848 | c.609G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5863 | c.624G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5873 | c.634A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5882 | c.643_645delCAAinsAC | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | Uncertain significance | |||||
gyrB | 5887 | p.Asp216Glu | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 5902 | c.663A>G | synonymous_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6086 | p.Thr283Pro | missense_variant | 0.9 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6091 | c.852G>C | synonymous_variant | 0.94 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6100 | c.861G>C | synonymous_variant | 0.96 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6115 | c.876A>G | synonymous_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6123 | p.Ala295Gly | missense_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6127 | c.888G>C | synonymous_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6133 | c.894G>C | synonymous_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6136 | c.897G>A | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6148 | c.909C>G | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6169 | c.930C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6190 | c.951A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6209 | c.970C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6217 | c.978G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6259 | p.Asp340Glu | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6298 | c.1059C>T | synonymous_variant | 0.98 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 6325 | c.-977C>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6361 | c.-941G>A | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6379 | c.-923C>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6382 | c.-920A>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6388 | c.-914T>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6400 | c.-902C>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6403 | c.-899T>C | upstream_gene_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6415 | c.-887G>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6427 | c.-875T>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6598 | c.-704C>G | upstream_gene_variant | 0.92 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6602 | c.-700C>T | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6610 | c.-692C>G | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6613 | c.-689A>C | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6616 | c.-686A>G | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6634 | c.-668T>C | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6637 | c.-665T>G | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6640 | c.-662A>C | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6652 | c.-650C>G | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6727 | c.-575G>T | upstream_gene_variant | 0.99 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.99 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.99 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.99 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6778 | c.-524C>T | upstream_gene_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6790 | c.-512C>T | upstream_gene_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.98 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6824 | c.1585C>T | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.98 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.98 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6911 | p.Asn558His | missense_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.97 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.96 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6931 | c.-371A>T | upstream_gene_variant | 0.95 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6937 | c.1698G>A | synonymous_variant | 0.93 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 6941 | c.-361C>T | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.93 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 6955 | c.-347G>A | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 6982 | c.-320A>C | upstream_gene_variant | 0.92 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7000 | c.-302C>G | upstream_gene_variant | 0.94 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7006 | c.-296T>G | upstream_gene_variant | 0.95 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 7012 | c.1773G>C | synonymous_variant | 0.95 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7018 | c.-284G>C | upstream_gene_variant | 0.95 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7021 | c.-281G>C | upstream_gene_variant | 0.95 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7033 | c.-269G>C | upstream_gene_variant | 0.95 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 7051 | p.Glu604Asp | missense_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 7057 | c.1818C>T | synonymous_variant | 0.93 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 7060 | c.1821T>C | synonymous_variant | 0.93 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7066 | c.-236G>C | upstream_gene_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7078 | c.-224A>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7081 | c.-221T>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 7093 | c.1854T>C | synonymous_variant | 0.92 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7099 | c.-203G>A | upstream_gene_variant | 0.9 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7108 | c.-194G>A | upstream_gene_variant | 0.92 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7147 | c.-155G>C | upstream_gene_variant | 0.9 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7165 | c.-137C>G | upstream_gene_variant | 0.96 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7178 | c.-124T>C | upstream_gene_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 7198 | c.1959C>A | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrB | 7216 | c.1977G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7225 | c.-77T>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7237 | c.-65C>T | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7243 | c.-59G>A | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrB | 7246 | c.2007T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7252 | c.-50G>C | upstream_gene_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7355 | c.54T>C | synonymous_variant | 0.95 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7475 | c.174A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7487 | c.186C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7490 | c.189C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7571 | c.270G>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7607 | c.306C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7626 | c.325C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7637 | c.336C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7676 | c.375G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7683 | c.382A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7697 | c.396C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7728 | c.427_429delAGGinsCC | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7760 | c.459C>T | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7799 | c.498A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7838 | c.537C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7862 | c.561C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7883 | c.582G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7884 | c.583_585delCGTinsGC | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7892 | c.591G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7898 | p.Asp199Glu | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7919 | p.Glu206Asp | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7923 | p.His208Tyr | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7928 | p.Asp209Glu | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7942 | p.Glu214Ala | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7955 | c.654G>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 7958 | c.657C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7963 | p.Gly221Glu | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7970 | c.669T>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7976 | c.675C>A | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7979 | c.678G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7992 | p.Ala231Ser | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 7997 | c.696A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8036 | c.735A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8039 | c.738T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8054 | c.753T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8057 | c.756A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8069 | c.768T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8078 | c.777A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8090 | c.789C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8096 | c.795T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8099 | c.798T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8174 | c.873C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.99 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8234 | c.933T>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8235 | c.934_936delTTAinsCG | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8283 | c.982_984delATCinsCG | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8327 | c.1026C>A | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8420 | c.1119T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8423 | c.1122G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8442 | c.1141C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8453 | c.1152A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8462 | c.1161A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8486 | c.1185T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8489 | c.1188A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8498 | c.1197C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8519 | c.1218A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8537 | c.1236G>A | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8552 | c.1251C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8556 | p.Ala419Gln | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8562 | c.1261C>T | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8576 | c.1275C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8597 | c.1296C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8603 | c.1302A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8645 | c.1344C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8717 | c.1416C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8720 | c.1419G>A | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8732 | c.1431G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8735 | c.1434C>T | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8765 | p.Asp488Glu | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
gyrA | 8779 | p.Asp493Ala | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8786 | c.1485T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8796 | c.1495_1497delATCinsGG | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8801 | c.1500G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8852 | c.1551T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8858 | c.1557T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8867 | c.1566A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8870 | c.1569G>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8873 | c.1572A>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8945 | c.1644G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8951 | c.1650G>A | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.99 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
gyrA | 9023 | c.1722A>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9029 | c.1728T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9062 | c.1761C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9068 | c.1767G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9071 | c.1770G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9074 | c.1773G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9080 | c.1779G>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9099 | c.1798_1800delTTAinsCG | frameshift_variant&missense_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9104 | c.1803C>G | synonymous_variant | 0.91 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9119 | c.1818A>G | synonymous_variant | 0.92 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9122 | c.1821C>G | synonymous_variant | 0.92 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9161 | c.1860C>T | synonymous_variant | 0.93 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9164 | c.1863G>C | synonymous_variant | 0.94 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9182 | c.1881T>C | synonymous_variant | 0.97 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9191 | c.1890G>C | synonymous_variant | 0.97 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9200 | c.1899A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9227 | c.1926C>G | synonymous_variant | 0.98 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9230 | c.1929T>C | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9233 | c.1932C>T | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9242 | c.1941A>C | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.99 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9278 | c.1977G>C | synonymous_variant | 0.98 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9281 | c.1980C>G | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9284 | c.1983T>C | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.98 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9311 | c.2010C>T | synonymous_variant | 0.98 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9413 | c.2112G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9605 | c.2304C>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9611 | p.Asp770Glu | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9626 | c.2325T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9629 | c.2328C>G | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9630 | p.Val777Ile | missense_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9650 | c.2349G>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9665 | c.2364A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9666 | p.Arg789Gly | missense_variant | 1.0 | moxifloxacin | Uncertain significance |
levofloxacin | Uncertain significance | |||||
gyrA | 9674 | c.2373T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9701 | c.2400T>C | synonymous_variant | 1.0 | moxifloxacin | Not assoc w R - Interim |
levofloxacin | Not assoc w R - Interim | |||||
gyrA | 9704 | c.2403T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9708 | c.2407T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9722 | c.2421C>T | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9734 | c.2433A>G | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
gyrA | 9738 | c.2437T>C | synonymous_variant | 1.0 | moxifloxacin | |
levofloxacin | ||||||
Rv0010c | 13879 | c.-321T>G | upstream_gene_variant | 0.94 | isoniazid | |
Rv0010c | 13890 | c.-332T>C | upstream_gene_variant | 0.97 | isoniazid | |
Rv0010c | 13893 | c.-335T>G | upstream_gene_variant | 0.97 | isoniazid | |
Rv0010c | 13903 | c.-345A>G | upstream_gene_variant | 0.98 | isoniazid | |
Rv0010c | 13909 | c.-351G>C | upstream_gene_variant | 0.98 | isoniazid | |
fgd1 | 490803 | c.21T>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490812 | c.30A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490815 | c.33G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490827 | c.45C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490833 | c.51G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490842 | c.60C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490851 | c.69A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490887 | c.105G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490902 | c.120T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490905 | c.123T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490911 | c.129T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490917 | c.135C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 490962 | c.180T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491038 | p.Ile86Val | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491043 | c.261T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491049 | c.267T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491063 | p.Gly94Ala | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491137 | p.Glu119Gln | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491166 | c.384G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491286 | c.504G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491292 | c.510G>C | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491295 | c.513C>G | synonymous_variant | 0.97 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491296 | p.Val172Ile | missense_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491319 | c.537G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491331 | c.549G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491349 | c.567T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491364 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491367 | c.585G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491453 | p.Gly224Asp | missense_variant | 1.0 | clofazimine | Uncertain significance |
pretomanid | ||||||
delamanid | Uncertain significance | |||||
fgd1 | 491472 | c.690A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491502 | c.720G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491508 | c.726A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491509 | c.727T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491526 | c.744T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491532 | c.750G>T | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fgd1 | 491542 | c.760T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491547 | c.765A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491550 | c.768T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491583 | c.801G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491595 | c.813C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491601 | c.819T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491610 | c.828A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491616 | c.834A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491643 | c.861G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
mshA | 574616 | c.-732G>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574625 | c.-723C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574650 | c.-698A>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574655 | c.-693C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574664 | c.-684G>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574671 | c.-677_-675delGCAinsCTG | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574676 | c.-672G>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574683 | c.-665T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 574688 | c.-660G>C | upstream_gene_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 574694 | c.-654C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 574700 | c.-648C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575081 | c.-267A>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575084 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575117 | c.-231T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575118 | c.-230A>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | Uncertain significance | |||||
mshA | 575123 | c.-225A>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575124 | c.-224_-222delGGGinsCC | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575137 | c.-211C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575144 | c.-204T>C | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575153 | c.-195C>G | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575154 | c.-194_-192delGTGinsCC | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575161 | c.-187_-186delTTinsCC | upstream_gene_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575521 | c.174A>C | synonymous_variant | 0.9 | ethionamide | |
isoniazid | ||||||
mshA | 575527 | c.180G>C | synonymous_variant | 0.91 | ethionamide | |
isoniazid | ||||||
mshA | 575536 | c.189T>C | synonymous_variant | 0.89 | ethionamide | |
isoniazid | ||||||
mshA | 575542 | c.195C>G | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575561 | p.Met72Val | missense_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575569 | c.222A>G | synonymous_variant | 0.88 | ethionamide | |
isoniazid | ||||||
mshA | 575571 | p.Ser75Thr | missense_variant | 0.88 | ethionamide | |
isoniazid | ||||||
mshA | 575575 | c.228G>C | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575587 | c.240C>A | synonymous_variant | 0.91 | ethionamide | |
isoniazid | ||||||
mshA | 575590 | c.243T>C | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575593 | c.246G>C | synonymous_variant | 0.92 | ethionamide | |
isoniazid | ||||||
mshA | 575623 | c.276C>G | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575629 | c.282A>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575635 | c.288A>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575638 | c.291T>C | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575641 | c.294A>G | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575648 | p.Val101Gln | missense_variant | 0.94 | ethionamide | |
isoniazid | ||||||
mshA | 575659 | c.312A>G | synonymous_variant | 0.93 | ethionamide | |
isoniazid | ||||||
mshA | 575665 | c.318G>C | synonymous_variant | 0.96 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575689 | c.342G>C | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575695 | c.348C>G | synonymous_variant | 0.98 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 575704 | c.357T>C | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575705 | c.358T>C | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575713 | c.366G>A | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575734 | c.387T>G | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575737 | c.390T>C | synonymous_variant | 0.96 | ethionamide | |
isoniazid | ||||||
mshA | 575746 | c.399C>G | synonymous_variant | 0.98 | ethionamide | |
isoniazid | ||||||
mshA | 575767 | c.420G>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575771 | p.Val142Ser | missense_variant | 0.95 | ethionamide | |
isoniazid | ||||||
mshA | 575779 | c.432A>G | synonymous_variant | 0.99 | ethionamide | |
isoniazid | ||||||
mshA | 575821 | c.474G>C | synonymous_variant | 0.99 | ethionamide | |
isoniazid | ||||||
mshA | 575824 | c.477T>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575878 | c.531A>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575884 | c.537G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 575893 | c.546C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576163 | c.816A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576184 | c.837A>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576193 | c.846T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576197 | c.850C>T | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576205 | c.858G>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
mshA | 576211 | c.864C>G | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576214 | c.867G>A | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576215 | c.868T>C | synonymous_variant | 1.0 | ethionamide | |
isoniazid | ||||||
mshA | 576233 | c.886_888delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
isoniazid | Uncertain significance | |||||
mshA | 576247 | c.900A>G | synonymous_variant | 0.94 | ethionamide | |
isoniazid | ||||||
ccsA | 619502 | c.-389_-388delAAinsCG | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619507 | c.-384A>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619531 | c.-360T>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619535 | c.-356_-354delCAAinsGCG | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619552 | c.-339A>G | upstream_gene_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619555 | c.-336C>G | upstream_gene_variant | 0.88 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619558 | c.-333G>C | upstream_gene_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619564 | c.-327C>G | upstream_gene_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619570 | c.-321G>C | upstream_gene_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619574 | c.-317G>A | upstream_gene_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619579 | c.-312G>C | upstream_gene_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619591 | c.-300G>C | upstream_gene_variant | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619627 | c.-264C>G | upstream_gene_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619633 | c.-258G>A | upstream_gene_variant | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619634 | c.-257T>A | upstream_gene_variant | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619648 | c.-243C>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619654 | c.-237A>C | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619655 | c.-236A>G | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619669 | c.-222G>C | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619672 | c.-219A>C | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619697 | c.-194_-192delAGGinsCC | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619947 | c.57C>G | synonymous_variant | 0.9 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619953 | c.63C>G | synonymous_variant | 0.9 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 619969 | p.Val27Ile | missense_variant | 0.9 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R | |||||
kanamycin | Uncertain significance | |||||
ccsA | 620153 | p.Ile88Thr | missense_variant | 0.82 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620157 | c.267G>C | synonymous_variant | 0.82 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620160 | c.270A>G | synonymous_variant | 0.82 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620169 | c.279G>C | synonymous_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620173 | c.283_285delGTCinsCG | frameshift_variant&missense_variant | 0.83 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620198 | p.Gln103Leu | missense_variant | 0.86 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620245 | c.355T>C | synonymous_variant | 0.96 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620249 | p.Ser120Cys | missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620254 | c.364_366delCTCinsTG | frameshift_variant&missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620257 | p.Ile123Val | missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620265 | c.375C>G | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620269 | p.Val127Ile | missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620275 | c.385C>T | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620283 | c.393T>C | synonymous_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620284 | p.Ala132Pro | missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.95 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>C | synonymous_variant | 0.97 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 0.98 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.99 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620433 | c.543C>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620436 | c.546T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620439 | c.549T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620445 | c.555A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620460 | c.570T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620461 | p.Val191Ile | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620481 | c.591T>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620482 | p.Val198Leu | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620490 | c.600A>C | synonymous_variant | 1.0 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620495 | p.Arg202Pro | missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620589 | c.699G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620598 | c.708C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620607 | c.717T>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620619 | c.729G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620622 | c.732G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620631 | c.741T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620703 | c.813G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620710 | c.820_822delGTGinsAC | frameshift_variant&missense_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620718 | c.828G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620721 | c.831G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620730 | c.840C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620734 | c.844C>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620745 | c.855G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620748 | c.858T>A | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620784 | c.894C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620787 | c.897C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620809 | c.919C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620829 | c.939G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620835 | c.945C>G | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620838 | c.948C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620844 | c.954C>T | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620847 | c.957G>C | synonymous_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 656031 | c.1440A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656037 | c.1434G>A | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656052 | c.1419A>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656073 | c.1396_1398delTTGinsCC | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 656085 | c.1386A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656088 | c.1383A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656091 | c.1380T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656097 | c.1374G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656112 | c.1359C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656118 | c.1353C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656265 | c.1206G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656268 | p.Met401Ile | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656277 | c.1194C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656289 | c.1182C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656298 | c.1173G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656304 | c.1167T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656511 | c.960T>C | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656526 | p.Glu315Asp | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656535 | c.936C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656539 | p.Ser311Ala | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656568 | c.903G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656582 | p.Leu297Met | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656583 | c.888A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656589 | c.882T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656604 | c.867G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656832 | c.639G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656838 | c.633A>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656841 | c.630G>A | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656853 | c.618A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656859 | p.Glu204Ala | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656865 | c.606G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656872 | p.Thr200Ser | missense_variant | 1.0 | ethionamide | |
Rv0565c | 656876 | c.595C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
Rv0565c | 656880 | c.591C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656883 | c.586_588delATCinsCG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 656889 | c.582A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 656901 | c.570C>A | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657160 | p.Glu104Arg | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657171 | c.300T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657189 | c.282C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657192 | p.Met93Thr | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657196 | p.Asp92Ala | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657219 | p.Ala84Val | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657222 | c.249C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657231 | c.238_240delATCinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657237 | c.234A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657242 | p.Glu77Lys | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 1.0 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657291 | c.180C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657300 | c.171C>T | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657318 | c.153T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657324 | c.147C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657327 | c.144C>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657342 | c.129T>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657347 | c.124A>C | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657348 | c.123A>G | synonymous_variant | 1.0 | ethionamide | |
Rv0565c | 657357 | c.112_114delACCinsGG | frameshift_variant&missense_variant | 1.0 | ethionamide | Uncertain significance |
Rv0565c | 657563 | c.-93T>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657571 | c.-101T>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657572 | c.-102A>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657578 | c.-108T>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657592 | c.-122A>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657596 | c.-126G>C | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657602 | c.-132C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657632 | c.-162G>A | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657639 | c.-169C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657641 | c.-171C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657656 | c.-186C>T | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657719 | c.-249C>G | upstream_gene_variant | 1.0 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 1.0 | ethionamide | |
hadA | 728303 | c.-3626_*5892del | transcript_ablation | 0.95 | isoniazid | Uncertain significance |
hadA | 731732 | c.-198G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731741 | c.-189G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731747 | c.-183T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731753 | c.-177A>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731792 | c.-138G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731801 | c.-129C>G | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731816 | c.-114G>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731833 | c.-97T>A | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731840 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
hadA | 731962 | c.33T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 731968 | c.39G>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 731971 | c.42T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 731980 | c.51C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
hadA | 732004 | c.75T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732016 | c.87C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
hadA | 732025 | c.96T>G | synonymous_variant | 1.0 | isoniazid | |
hadA | 732028 | c.99A>G | synonymous_variant | 1.0 | isoniazid | |
hadA | 732238 | c.309G>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732253 | c.324T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732259 | c.330T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732268 | c.339T>G | synonymous_variant | 1.0 | isoniazid | |
hadA | 732270 | p.Glu114Val | missense_variant | 1.0 | isoniazid | |
hadA | 732272 | p.Ala115Ser | missense_variant | 1.0 | isoniazid | |
hadA | 732295 | c.366G>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732304 | c.375C>T | synonymous_variant | 1.0 | isoniazid | |
hadA | 732305 | p.Ile126Val | missense_variant | 1.0 | isoniazid | |
hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
hadA | 732329 | p.Leu134Val | missense_variant | 1.0 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 1.0 | isoniazid | |
hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
hadA | 732389 | p.Ser154Thr | missense_variant | 1.0 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
nusG | 734078 | c.-176C>A | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734093 | c.-161A>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734102 | c.-152G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734111 | c.-143A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734114 | c.-140A>G | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734120 | c.-134T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734129 | c.-125G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734132 | c.-122G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734135 | c.-119G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734144 | c.-110G>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734147 | c.-107T>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734173 | c.-81C>G | upstream_gene_variant | 0.91 | rifampicin | |
nusG | 734180 | c.-74T>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734183 | c.-71C>T | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734186 | c.-68G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734205 | c.-49A>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734208 | c.-46T>C | upstream_gene_variant | 1.0 | rifampicin | |
nusG | 734340 | c.87T>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734349 | c.96C>T | synonymous_variant | 1.0 | rifampicin | |
nusG | 734352 | c.99T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734370 | c.117A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734373 | c.120G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734376 | c.123G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734407 | c.154_156delGTTinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
nusG | 734421 | c.168A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734424 | c.171G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734442 | c.189G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734481 | c.228C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734499 | c.246G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734595 | c.342C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734634 | c.381G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734643 | c.390G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734652 | c.399T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734655 | c.402G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734658 | c.405A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
nusG | 734661 | c.408A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734664 | c.411T>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734673 | c.420A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734679 | c.426C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734680 | c.427_429delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
nusG | 734703 | c.450T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734709 | c.456T>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734715 | c.462G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734718 | c.465G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734719 | p.Ser156Ala | missense_variant | 1.0 | rifampicin | |
nusG | 734726 | p.Arg158Lys | missense_variant | 1.0 | rifampicin | |
nusG | 734732 | p.Ala160Val | missense_variant | 1.0 | rifampicin | |
nusG | 734754 | c.501G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734757 | c.504T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734778 | c.525G>C | synonymous_variant | 0.96 | rifampicin | |
nusG | 734781 | c.528A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734792 | p.Val180Ala | missense_variant | 1.0 | rifampicin | |
nusG | 734794 | p.Val181Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
nusG | 734820 | c.567A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734826 | c.573A>G | synonymous_variant | 0.99 | rifampicin | |
nusG | 734829 | c.576C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
nusG | 734832 | c.579C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734841 | c.588G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734847 | c.594T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734853 | c.600A>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734854 | c.601T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734865 | c.612G>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734882 | p.Ala210Gly | missense_variant | 1.0 | rifampicin | |
nusG | 734886 | c.633A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734931 | c.678A>G | synonymous_variant | 1.0 | rifampicin | |
nusG | 734940 | c.687G>A | synonymous_variant | 1.0 | rifampicin | |
nusG | 734949 | c.696T>C | synonymous_variant | 1.0 | rifampicin | |
nusG | 734950 | p.Gly233Ser | missense_variant | 1.0 | rifampicin | |
rpoB | 759644 | c.-163T>A | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 759647 | c.-160T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760070 | c.264T>G | synonymous_variant | 0.92 | rifampicin | |
rpoB | 760088 | c.282C>G | synonymous_variant | 0.89 | rifampicin | |
rpoB | 760091 | c.285G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 760101 | c.295T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 760106 | c.300G>T | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760112 | c.306T>C | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760118 | c.312T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
rpoB | 760121 | c.315T>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoB | 760130 | p.Asp108Glu | missense_variant | 0.97 | rifampicin | Uncertain significance |
rpoB | 760139 | c.333A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 760142 | c.336C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 760340 | c.534G>C | synonymous_variant | 0.99 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760406 | c.600G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760634 | c.828T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760655 | c.849A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760718 | c.912C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760721 | c.915C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760751 | c.945G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760757 | c.951T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760759 | p.Val318Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 760763 | c.957C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760769 | c.963C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760775 | c.969G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760776 | c.970_972delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760845 | p.Thr347Pro | missense_variant | 0.99 | rifampicin | |
rpoB | 760859 | c.1053T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760869 | p.Val355Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761171 | c.1365C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761183 | c.1377T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761213 | c.1407G>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761222 | c.1416G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761231 | c.1425C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761301 | c.1495C>A | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 1.0 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761723 | c.1917_1919delAGAinsG | frameshift_variant&synonymous_variant | 1.0 | rifampicin | |
rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.98 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761847 | p.Cys681Ser | missense_variant | 0.98 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761864 | c.2058G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.96 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.97 | rifampicin | |
rpoB | 761906 | c.2100C>G | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761909 | c.2103T>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761912 | c.2106T>C | synonymous_variant | 0.98 | rifampicin | |
rpoB | 761915 | p.Asp703Glu | missense_variant | 0.98 | rifampicin | |
rpoB | 761916 | p.Asp704Asn | missense_variant | 0.98 | rifampicin | |
rpoB | 761930 | c.2124G>A | synonymous_variant | 0.99 | rifampicin | |
rpoB | 761948 | c.2142G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 761954 | c.2148C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 761999 | c.2193G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762008 | c.2202C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762140 | c.2334G>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>G | synonymous_variant | 0.99 | rifampicin | |
rpoB | 762254 | c.2448T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.98 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 762374 | c.-996G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762380 | c.-990T>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762404 | c.2598T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.99 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 762443 | c.-927G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762489 | p.Val895Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.91 | rifampicin | |
rpoB | 762510 | c.2704_2706delGCCinsCG | frameshift_variant&missense_variant | 0.88 | rifampicin | |
rpoC | 762521 | c.-849C>G | upstream_gene_variant | 0.98 | rifampicin | |
rpoC | 762533 | c.-837T>C | upstream_gene_variant | 0.98 | rifampicin | |
rpoC | 762536 | c.-834T>C | upstream_gene_variant | 0.97 | rifampicin | |
rpoC | 762537 | c.-833T>C | upstream_gene_variant | 0.97 | rifampicin | |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.97 | rifampicin | |
rpoC | 762581 | c.-789T>C | upstream_gene_variant | 0.94 | rifampicin | |
rpoC | 762582 | c.-788T>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762785 | p.Asp993Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762788 | c.2982G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 762794 | c.-576C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762799 | p.Ala998Gly | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762830 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762831 | c.3025_3026delAGinsTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762836 | c.-534C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762863 | c.3057T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 762929 | c.3123G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763076 | c.-294C>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763202 | c.-168A>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763205 | c.-165G>C | upstream_gene_variant | 1.0 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoB | 763268 | c.3462C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763402 | c.33C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763441 | c.72C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 763658 | c.289_291delCTTinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 763675 | c.306C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763709 | c.340C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763714 | c.345G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763768 | c.399C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763783 | c.414G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763819 | c.450G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763831 | c.462A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 1.0 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763960 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 763967 | p.Gly200Ser | missense_variant | 1.0 | rifampicin | |
rpoC | 763978 | c.609C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764161 | c.792G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 764203 | c.834G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 764282 | c.913_915delTCGinsAGC | synonymous_variant | 0.98 | rifampicin | |
rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764387 | c.1018_1020delTTGinsCC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764470 | c.1101C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764503 | c.1134G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764560 | c.1191T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764566 | c.1197C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764576 | c.1207_1208delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764581 | c.1212T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764779 | c.1410G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764968 | c.1599T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765034 | c.1665T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765041 | c.1672T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765047 | c.1678T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765073 | c.1704G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765076 | c.1707A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765079 | c.1710T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765085 | c.1716T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765103 | c.1734G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765326 | p.His653Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765349 | c.1980T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 1.0 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765541 | c.2172C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765578 | c.2209C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 1.0 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.99 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 765985 | c.2616C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.99 | rifampicin | Not assoc w R - Interim |
rpoC | 766009 | c.2640G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.99 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766069 | c.2700G>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 766096 | c.2727G>C | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766129 | c.2760C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766135 | c.2766G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766141 | c.2772C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766142 | c.2773C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766258 | c.2889T>C | synonymous_variant | 0.94 | rifampicin | |
rpoC | 766270 | c.2901G>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766273 | c.2904T>C | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766274 | p.Ala969Thr | missense_variant | 0.95 | rifampicin | |
rpoC | 766279 | c.2910C>G | synonymous_variant | 0.86 | rifampicin | |
rpoC | 766280 | p.Ser971Gly | missense_variant | 0.91 | rifampicin | |
rpoC | 766309 | c.2940G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
rpoC | 766312 | c.2943T>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766315 | c.2946C>G | synonymous_variant | 0.95 | rifampicin | |
rpoC | 766327 | c.2958C>G | synonymous_variant | 0.96 | rifampicin | |
rpoC | 766345 | c.2976T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766348 | c.2979A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 766363 | c.2994G>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766381 | c.3012C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766384 | c.3015A>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766444 | c.3075C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
rpoC | 766489 | c.3120G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766531 | c.3162G>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766549 | c.3180G>C | synonymous_variant | 0.98 | rifampicin | |
rpoC | 766573 | c.3204T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 766583 | c.3214_3216delGGTinsAC | frameshift_variant&missense_variant | 0.99 | rifampicin | |
rpoC | 766588 | c.3219G>A | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766591 | c.3222A>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 766607 | c.3238_3240delATCinsCG | frameshift_variant&missense_variant | 0.99 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766738 | c.3369G>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766942 | c.3573C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 766978 | c.3609C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 766996 | c.3627C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767074 | c.3705T>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>G | synonymous_variant | 0.99 | rifampicin | |
rpoC | 767158 | c.3789T>G | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767191 | c.3822C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767206 | c.3837C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
rpoC | 767209 | c.3840T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767212 | c.3843G>C | synonymous_variant | 1.0 | rifampicin | |
rpoC | 767221 | c.3852C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767230 | c.3861G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767233 | c.3864T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767263 | c.3894T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
rpoC | 767264 | p.Ala1299Gln | missense_variant | 1.0 | rifampicin | |
rpoC | 767275 | c.3906T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 767278 | c.3909T>C | synonymous_variant | 0.97 | rifampicin | |
rpoC | 767281 | c.3912C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
rpoC | 767284 | c.3915C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775856 | c.2625T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775864 | p.Ala873Ser | missense_variant | 0.68 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775865 | c.2616T>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775883 | c.2596_2598delATCinsTG | frameshift_variant&missense_variant | 0.73 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775886 | c.2595A>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775898 | c.2583G>A | synonymous_variant | 0.85 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775901 | c.2580G>A | synonymous_variant | 0.7 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775904 | c.2577G>A | synonymous_variant | 0.7 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.97 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775912 | c.2569C>A | synonymous_variant | 0.7 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775915 | p.Ala856Ser | missense_variant | 0.3 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.74 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.86 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775970 | c.2511G>C | synonymous_variant | 0.73 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775991 | c.2490G>A | synonymous_variant | 0.83 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775997 | c.2484T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776000 | c.2479_2481delCTGinsAC | frameshift_variant&missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776005 | p.Ile826Leu | missense_variant | 0.83 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776053 | c.2428T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776056 | p.Val809Leu | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776060 | c.2421C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776063 | c.2418C>T | synonymous_variant | 0.8 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776072 | c.2409C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776076 | p.Ala802Phe | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776084 | c.2397C>G | synonymous_variant | 0.8 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776102 | c.2377_2379delATCinsGG | frameshift_variant&missense_variant | 0.67 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776654 | c.1827A>T | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776665 | p.Thr606Ala | missense_variant | 1.0 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776678 | c.1803G>C | synonymous_variant | 0.94 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776693 | c.1788C>G | synonymous_variant | 0.71 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776735 | c.1744_1746delCGCinsAA | frameshift_variant&missense_variant | 0.29 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 776738 | p.Ile581Met | missense_variant | 0.61 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776744 | c.1737C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776753 | c.1728T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777143 | c.1338G>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777158 | c.1323C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777164 | c.1317C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777170 | c.1311T>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777173 | c.1308C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777176 | p.Glu435Asp | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777179 | c.1302G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777188 | c.1293T>C | synonymous_variant | 0.97 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777191 | c.1290C>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777194 | c.1287A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777203 | c.1278G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777206 | c.1275A>G | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777214 | p.Ala423Thr | missense_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777245 | c.1236G>C | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777251 | c.1230C>A | synonymous_variant | 1.0 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777254 | c.1227G>C | synonymous_variant | 0.9 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777268 | c.1213C>T | synonymous_variant | 0.9 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 777269 | c.1212T>G | synonymous_variant | 0.9 | clofazimine | |
bedaquiline | ||||||
rpsL | 781209 | c.-351C>G | upstream_gene_variant | 1.0 | streptomycin | |
rpsL | 781224 | c.-336T>C | upstream_gene_variant | 1.0 | streptomycin | |
rpsL | 781230 | c.-330T>C | upstream_gene_variant | 1.0 | streptomycin | |
rpsL | 781233 | c.-327G>C | upstream_gene_variant | 1.0 | streptomycin | |
rpsL | 781234 | c.-326G>T | upstream_gene_variant | 1.0 | streptomycin | |
rpsL | 781240 | c.-320A>T | upstream_gene_variant | 1.0 | streptomycin | |
rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781608 | c.49_51delAGTinsGC | frameshift_variant&missense_variant | 1.0 | streptomycin | Uncertain significance |
rpsL | 781631 | c.72G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.98 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.99 | linezolid | |
rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.99 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.99 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800794 | c.-15_-9delAGATTGGinsGAGTT | upstream_gene_variant | 1.0 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 1.0 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
rplC | 800874 | c.66A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800877 | c.69A>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800880 | c.72A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800889 | c.81C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800907 | c.99C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800916 | c.108A>G | synonymous_variant | 0.98 | linezolid | |
rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800939 | p.Arg44Gln | missense_variant | 1.0 | linezolid | |
rplC | 800946 | c.138T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800949 | c.141T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 800955 | c.147C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800967 | c.159C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800970 | c.162T>C | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
rplC | 800982 | c.174C>T | synonymous_variant | 1.0 | linezolid | |
rplC | 800985 | c.177A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 800994 | c.186C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801004 | p.Leu66Val | missense_variant | 1.0 | linezolid | |
rplC | 801105 | c.297A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801109 | c.301T>C | synonymous_variant | 1.0 | linezolid | Not assoc w R - Interim |
rplC | 801114 | c.306C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801127 | p.Ala107Thr | missense_variant | 1.0 | linezolid | |
rplC | 801132 | c.324T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801147 | c.339T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801150 | c.342G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801153 | c.345G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801156 | c.348T>A | synonymous_variant | 1.0 | linezolid | |
rplC | 801171 | c.363A>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801228 | c.420T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801246 | c.438C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801249 | c.441T>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 1.0 | linezolid | |
rplC | 801267 | c.459A>T | synonymous_variant | 1.0 | linezolid | |
rplC | 801270 | c.462T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801276 | c.468G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801279 | c.471G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801282 | c.474G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801300 | c.492C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801301 | c.493C>A | synonymous_variant | 1.0 | linezolid | |
rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801336 | c.528C>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 1.0 | linezolid | |
rplC | 801396 | c.588T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801417 | c.609T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 1.0 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 1.0 | linezolid | |
rplC | 801461 | c.653G>A | splice_region_variant&stop_retained_variant | 1.0 | linezolid | |
fbiC | 1303455 | c.525C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303464 | c.534A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303476 | c.546G>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303509 | c.579G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303560 | c.630G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303602 | c.672A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303611 | c.681G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303614 | c.684C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303617 | c.687C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303638 | c.708A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303660 | p.Val244Thr | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303695 | c.765T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303701 | c.771C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303728 | c.798G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303731 | c.801A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303732 | p.Ser268Ala | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303749 | c.819G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303752 | c.822A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1303755 | c.825T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303785 | c.855G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303881 | c.951G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.9 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303920 | c.990C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303923 | c.993C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303929 | c.999G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303973 | p.Gly348Ala | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303981 | p.Val351Ile | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303995 | c.1065C>T | synonymous_variant | 0.99 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304001 | c.1071C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304040 | c.1110C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304049 | c.1119T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304058 | c.1128G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304059 | c.1129C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304064 | c.1134G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304067 | c.1137G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304080 | p.Ala384Ser | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304091 | p.Asp387Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304092 | p.Met388Leu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304097 | c.1167G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304517 | c.1587C>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304520 | c.1590A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304523 | c.1593G>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304526 | c.1596T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304544 | c.1614T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304545 | p.Val539Thr | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304565 | c.1635C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304568 | c.1638T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304574 | c.1644C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304580 | c.1650T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304613 | c.1683T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304628 | c.1698G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304634 | c.1704C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304640 | c.1710A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304646 | c.1716T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304658 | c.1728C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304670 | c.1740G>T | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304671 | p.Val581Thr | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304675 | p.Gly582Glu | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304691 | c.1761G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304694 | c.1764A>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304703 | c.1773C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304715 | c.1785G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304724 | c.1794A>G | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304790 | c.1860C>G | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304808 | c.1878C>G | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304811 | c.1881C>G | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304817 | c.1887T>C | synonymous_variant | 0.99 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304829 | c.1899T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304832 | c.1902C>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304853 | c.1923C>G | synonymous_variant | 0.98 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304872 | c.1942_1944delAGCinsTCG | synonymous_variant | 0.92 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304877 | c.1947T>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304925 | c.1995G>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304928 | c.1998T>C | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304934 | c.2004C>G | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304937 | c.2007G>C | synonymous_variant | 0.93 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304940 | c.2010A>G | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304946 | c.2016G>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304958 | c.2028T>G | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304991 | c.2061G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304995 | c.2065T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305006 | c.2076A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305012 | c.2082G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305021 | c.2091C>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305027 | c.2097G>A | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305033 | c.2103T>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305276 | c.2346G>C | synonymous_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305279 | p.His783Gln | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305282 | c.2352T>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305297 | c.2367G>C | synonymous_variant | 0.97 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305300 | c.2370A>G | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305303 | c.2373T>C | synonymous_variant | 0.95 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305311 | p.Arg794Gln | missense_variant | 0.96 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305336 | c.2406T>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305381 | c.2451G>C | synonymous_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305397 | p.Glu823Gln | missense_variant | 0.98 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>G | synonymous_variant | 1.0 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305420 | c.2490C>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305423 | c.2493T>C | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305430 | p.Val834Thr | missense_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305444 | c.2514A>G | synonymous_variant | 1.0 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305453 | c.2523C>G | synonymous_variant | 0.94 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364661 | c.249C>G | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364667 | c.255T>C | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364676 | c.264C>G | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364679 | c.267T>C | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364691 | c.279T>C | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364712 | c.300T>C | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364718 | c.306C>T | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364727 | c.315C>T | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364736 | c.324T>C | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
sigE | 1364742 | c.330A>G | synonymous_variant | 0.95 | pyrazinamide | |
sigE | 1364748 | c.336G>C | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364763 | c.351T>C | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364767 | c.355A>C | synonymous_variant | 0.97 | pyrazinamide | |
sigE | 1364784 | c.372C>G | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364802 | c.390C>A | synonymous_variant | 0.98 | pyrazinamide | |
sigE | 1364811 | c.399A>G | synonymous_variant | 0.96 | pyrazinamide | |
sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364835 | c.423C>G | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364862 | c.450C>G | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364866 | c.454_456delGCTinsTG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
sigE | 1364887 | c.475_477delTTAinsCG | frameshift_variant&missense_variant | 1.0 | pyrazinamide | Uncertain significance |
sigE | 1364904 | p.Asp164Glu | missense_variant | 1.0 | pyrazinamide | |
sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
sigE | 1364928 | c.516C>T | synonymous_variant | 0.9 | pyrazinamide | |
Rv1258c | 1406612 | c.729G>A | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406636 | c.705C>G | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406641 | p.Thr234Ala | missense_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406648 | c.693T>C | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406653 | p.Met230Leu | missense_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406657 | c.684C>G | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406660 | c.681C>G | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406668 | c.673T>C | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406669 | c.672A>G | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
Rv1258c | 1406690 | c.651C>G | synonymous_variant | 1.0 | streptomycin | |
isoniazid | ||||||
pyrazinamide | ||||||
atpE | 1460816 | c.-229T>C | upstream_gene_variant | 0.96 | bedaquiline | |
atpE | 1460831 | c.-214T>C | upstream_gene_variant | 0.96 | bedaquiline | |
atpE | 1460840 | c.-205A>G | upstream_gene_variant | 0.96 | bedaquiline | |
atpE | 1460852 | c.-193C>G | upstream_gene_variant | 0.95 | bedaquiline | |
atpE | 1460855 | c.-190T>C | upstream_gene_variant | 0.95 | bedaquiline | |
atpE | 1460858 | c.-187C>G | upstream_gene_variant | 0.95 | bedaquiline | |
atpE | 1461097 | p.Ala18Gly | missense_variant | 0.94 | bedaquiline | |
atpE | 1461101 | c.57T>C | synonymous_variant | 0.94 | bedaquiline | |
atpE | 1461107 | c.63C>G | synonymous_variant | 0.95 | bedaquiline | |
atpE | 1461113 | c.69C>T | synonymous_variant | 0.96 | bedaquiline | |
atpE | 1461132 | p.Val30Ile | missense_variant | 1.0 | bedaquiline | |
atpE | 1461149 | c.105T>G | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461150 | c.106_108delATCinsGT | frameshift_variant&missense_variant | 1.0 | bedaquiline | |
atpE | 1461159 | p.Val39Ile | missense_variant | 1.0 | bedaquiline | Uncertain significance |
atpE | 1461185 | c.141G>C | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461189 | c.145C>T | synonymous_variant | 0.99 | bedaquiline | |
atpE | 1461194 | c.150C>T | synonymous_variant | 0.99 | bedaquiline | |
atpE | 1461197 | c.153A>G | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461219 | c.175T>C | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461224 | c.180T>C | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461233 | c.189A>G | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461254 | c.210T>C | synonymous_variant | 1.0 | bedaquiline | |
atpE | 1461275 | c.231T>C | synonymous_variant | 1.0 | bedaquiline | |
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472030 | n.185G>A | non_coding_transcript_exon_variant | 0.98 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472044 | n.199G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.99 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473290 | n.1445delCinsTTT | non_coding_transcript_exon_variant | 0.95 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrl | 1473668 | n.11C>T | non_coding_transcript_exon_variant | 0.92 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473944 | n.287G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473945 | n.288T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
linezolid |