TB-Profiler result

Run: ERR3797048
Summary

Run ID: ERR3797048

Sample name:

Date: 2024-03-26T15:56:56.084536

Number of reads: 299376

Percentage reads mapped: 11.5

Median coverage: 1.0

Strain: La3;lineage4.9

Spoligotype:

Drug-resistance: Other

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 0.98
lineage4.9 Euro-American (H37Rv-like) None 0.93
La3 M.orygis None 0.14
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fbiC c.550_552delCAAinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.595_597delTCGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fbiC 1303480 c.550_552delCAAinsGG frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fbiC 1303525 c.595_597delTCGinsAC frameshift_variant&missense_variant 1.0 delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 624 c.624C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 636 c.636C>G synonymous_variant 1.0 isoniazid
dnaA 639 c.639C>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 645 c.645A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 651 c.651G>C synonymous_variant 1.0 isoniazid
dnaA 654 c.654A>G synonymous_variant 1.0 isoniazid
dnaA 663 c.663A>C synonymous_variant 1.0 isoniazid
dnaA 666 c.666C>G synonymous_variant 1.0 isoniazid
dnaA 672 c.672T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 678 c.678A>G synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 690 c.690G>C synonymous_variant 1.0 isoniazid
dnaA 693 c.693A>C synonymous_variant 1.0 isoniazid
dnaA 699 c.699G>A synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 702 c.702C>G synonymous_variant 1.0 isoniazid
dnaA 705 c.705A>G synonymous_variant 1.0 isoniazid
dnaA 708 c.708T>C synonymous_variant 1.0 isoniazid
dnaA 741 c.741T>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 750 c.750C>G synonymous_variant 1.0 isoniazid
dnaA 767 p.Val256Ala missense_variant 1.0 isoniazid
dnaA 769 c.769_771delGCAinsTG frameshift_variant&stop_gained 0.94 isoniazid Uncertain significance
dnaA 777 c.777A>G synonymous_variant 1.0 isoniazid
dnaA 783 c.783C>T synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 792 c.792C>T synonymous_variant 1.0 isoniazid
dnaA 795 c.795A>C synonymous_variant 1.0 isoniazid Not assoc w R - Interim
dnaA 799 c.799_801delGTGinsAC frameshift_variant&missense_variant 1.0 isoniazid Uncertain significance
dnaA 805 c.805_807delTTGinsCC frameshift_variant&missense_variant 0.93 isoniazid Uncertain significance
dnaA 813 c.813C>T synonymous_variant 0.93 isoniazid
dnaA 822 c.822A>G synonymous_variant 0.93 isoniazid
dnaA 828 c.828T>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 831 c.831A>G synonymous_variant 0.93 isoniazid
dnaA 837 c.837A>G synonymous_variant 0.93 isoniazid
dnaA 840 p.Glu280Asp missense_variant 0.93 isoniazid
dnaA 843 c.843T>C synonymous_variant 0.93 isoniazid Not assoc w R - Interim
dnaA 846 c.846T>C synonymous_variant 0.93 isoniazid
dnaA 849 c.849A>G synonymous_variant 0.94 isoniazid
gyrB 6139 c.900G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6172 c.933C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAC frameshift_variant&missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6265 c.1026C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6268 c.1029C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6295 c.1056A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6301 c.1062G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6307 c.1068T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6565 c.-737G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6571 c.-731T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6583 c.-719G>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6590 p.Arg451Ser missense_variant 0.97 levofloxacin
moxifloxacin
gyrA 6610 c.-692C>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6613 c.-689A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6616 c.-686A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6619 c.-683T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6622 c.-680C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6634 c.-668T>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6637 c.-665T>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6640 c.-662A>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6643 c.-659A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6652 c.-650C>T upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>C upstream_gene_variant 0.98 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>C upstream_gene_variant 0.96 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 0.95 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrB 6775 c.1536G>C synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6793 c.1554T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6794 c.1555_1557delATCinsCG frameshift_variant&missense_variant 0.93 levofloxacin Uncertain significance
moxifloxacin
gyrB 6798 p.Gly520Ala missense_variant 0.93 levofloxacin Not assoc w R
moxifloxacin Uncertain significance
gyrA 7084 c.-218A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7093 c.1854T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7099 c.-203G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7100 c.1861T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7129 c.-173T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7132 c.-170T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7141 c.-161T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7144 c.-158A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7150 c.-152G>A upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 7153 c.1914G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7168 c.-134C>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 7177 c.-125G>A upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrA 7178 c.-124T>C upstream_gene_variant 0.94 levofloxacin
moxifloxacin
gyrB 7186 c.1947C>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 7210 p.Asp657Glu missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7421 c.120G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7424 c.123G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7499 c.198G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7506 c.205_207delAGCinsGA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7532 c.231T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7547 c.246C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7569 p.Ala90Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7607 c.306C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7613 c.312G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7694 c.393A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7697 c.396C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7706 c.405C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7715 c.414G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCT frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7778 c.477G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7793 c.492G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7799 c.498A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7814 c.513C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7835 c.534A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7841 c.540C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7847 c.546G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7992 c.691_693delGCCinsTA frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7997 c.696A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8020 p.Thr240Ile missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8022 p.Ala241His missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8035 p.Lys245Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8039 c.738T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8048 c.747C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8054 c.753T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8057 c.756A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8066 c.765A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8069 c.768T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8076 c.775_777delGTAinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8090 c.789C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8099 c.798T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8106 c.805_807delCTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8111 c.810G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8168 c.867A>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8177 c.876A>C synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8852 c.1551T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8885 c.1584C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 8897 c.1596T>C synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8915 c.1614A>G synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8918 c.1617C>G synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8924 c.1623C>T synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 8930 c.1629C>T synonymous_variant 0.94 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8939 c.1638T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 0.93 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 0.91 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 0.9 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9017 c.1716C>A synonymous_variant 0.9 levofloxacin
moxifloxacin
gyrA 9068 c.1767G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9080 c.1779G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9086 c.1785C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9089 c.1788G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9099 c.1798_1800delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9113 c.1812C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9122 c.1821C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9134 c.1833C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9141 c.1840_1842delATTinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9145 p.Arg615Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9147 p.Gly616Ser missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9153 p.Thr618Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9179 c.1878C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9191 c.1890G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9197 c.1896G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9248 c.1947G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9257 c.1956C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9266 p.Asp655Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9284 c.1983T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9293 c.1992G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9299 c.1998G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9311 c.2010C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9318 c.2017C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 9324 c.2023_2025delTCGinsAGT synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9356 c.2055G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
mshA 575842 c.495G>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575884 c.537G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575893 c.546C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575917 c.570C>T synonymous_variant 1.0 ethionamide
isoniazid
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620712 c.822G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620718 c.828G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 657722 c.-252C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-263_-262delAGinsGA upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
nusG 734439 c.186C>G synonymous_variant 1.0 rifampicin
nusG 734451 c.198G>C synonymous_variant 1.0 rifampicin
nusG 734454 c.201A>G synonymous_variant 1.0 rifampicin
nusG 734460 c.207G>C synonymous_variant 1.0 rifampicin
nusG 734472 c.219T>C synonymous_variant 1.0 rifampicin
nusG 734475 c.222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734484 c.231C>T synonymous_variant 1.0 rifampicin
nusG 734508 c.255C>G synonymous_variant 1.0 rifampicin
nusG 734532 c.279A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 1.0 rifampicin
rpoB 760172 c.366G>C synonymous_variant 1.0 rifampicin
rpoB 760181 c.375T>G synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760199 c.393C>G synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760244 c.438G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760274 c.468G>A synonymous_variant 1.0 rifampicin
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760287 p.Ile161Val missense_variant 1.0 rifampicin
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>T synonymous_variant 1.0 rifampicin
rpoB 760337 c.531C>G synonymous_variant 0.94 rifampicin
rpoB 760340 c.534G>C synonymous_variant 1.0 rifampicin
rpoB 760343 c.537G>C synonymous_variant 1.0 rifampicin
rpoB 760353 p.Glu183Ser missense_variant 1.0 rifampicin
rpoB 760356 p.Thr184Ser missense_variant 1.0 rifampicin Uncertain significance
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760368 p.Ser188Ala missense_variant 1.0 rifampicin
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760380 p.Thr192Asp missense_variant 1.0 rifampicin
rpoB 760400 c.594G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760418 c.612G>A synonymous_variant 0.95 rifampicin
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 760475 c.669A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>T synonymous_variant 1.0 rifampicin
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760502 c.696C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760535 c.729C>G synonymous_variant 1.0 rifampicin
rpoB 760541 c.735G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760561 c.757_758delCG frameshift_variant 1.0 rifampicin
rpoB 760567 p.Ser254Trp missense_variant 1.0 rifampicin
rpoB 760568 c.762_763insGC frameshift_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760601 c.795C>T synonymous_variant 1.0 rifampicin
rpoB 760610 c.804G>C synonymous_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760625 c.819C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760634 c.828T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760715 c.909C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760724 c.918T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760928 c.1122G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761063 c.1257C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761084 c.1278C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 1.0 rifampicin
rpoB 761132 c.1326G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761147 c.1341C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761165 c.1359G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761171 c.1365C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761217 c.1411_1413delCCGinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761264 c.1458C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>T synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761339 c.1533C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761345 c.1539G>C synonymous_variant 1.0 rifampicin
rpoB 761346 p.Val514Thr missense_variant 1.0 rifampicin
rpoB 761354 c.1548C>T synonymous_variant 1.0 rifampicin
rpoB 761357 c.1551G>C synonymous_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761367 p.Glu521Gln missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Asp missense_variant 1.0 rifampicin
rpoB 761393 c.1587G>A synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761406 c.1600_1602delGTGinsAC frameshift_variant&missense_variant 0.92 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.9 rifampicin
rpoB 761555 c.1749G>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 761570 c.1764T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761606 c.1800C>G synonymous_variant 0.96 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>T synonymous_variant 1.0 rifampicin
rpoB 761681 c.1875G>A synonymous_variant 0.97 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 0.97 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 0.97 rifampicin
rpoB 761693 c.1887G>C synonymous_variant 0.97 rifampicin
rpoB 761705 c.1899C>T synonymous_variant 0.97 rifampicin
rpoB 761712 p.Val636Ile missense_variant 0.97 rifampicin
rpoB 761723 p.Glu639Asp missense_variant 0.96 rifampicin Not assoc w R
rpoB 761724 c.1918_1920delGAAinsAG frameshift_variant&missense_variant 0.96 rifampicin
rpoB 761728 p.Ser641Thr missense_variant 0.96 rifampicin
rpoB 761732 c.1926C>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoB 761735 c.1929C>G synonymous_variant 0.96 rifampicin
rpoB 761741 c.1935G>A synonymous_variant 0.96 rifampicin
rpoB 761747 c.1941G>T synonymous_variant 0.96 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 1.0 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.96 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.96 rifampicin
rpoB 761785 p.Thr660Ser missense_variant 0.96 rifampicin
rpoB 761789 c.1983G>C synonymous_variant 0.96 rifampicin
rpoB 761791 p.Arg662Gln missense_variant 0.92 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 1.0 rifampicin
rpoB 761834 c.2028T>G synonymous_variant 1.0 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 1.0 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 1.0 rifampicin
rpoB 761862 c.2056_2058delGCGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761867 c.2061C>A synonymous_variant 1.0 rifampicin
rpoB 761868 c.2062_2064delGACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761873 c.2067A>C synonymous_variant 1.0 rifampicin
rpoB 761891 c.2085G>C synonymous_variant 1.0 rifampicin
rpoB 761892 p.Ile696Leu missense_variant 1.0 rifampicin
rpoB 761903 c.2097T>C synonymous_variant 1.0 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 1.0 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 0.95 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 1.0 rifampicin
rpoB 761955 p.Ile717Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761972 c.2166C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762002 c.2196C>G synonymous_variant 1.0 rifampicin
rpoB 762008 c.2202C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762047 c.2241G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 1.0 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 1.0 rifampicin
rpoB 762137 c.2331C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762140 c.2334G>C synonymous_variant 1.0 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 1.0 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762156 c.2350_2352delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 0.98 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762245 c.2439G>T synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762296 c.2490G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 1.0 rifampicin
rpoB 762359 c.2553C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoB 762369 c.2563T>C synonymous_variant 1.0 rifampicin
rpoC 762374 c.-996G>C upstream_gene_variant 1.0 rifampicin
rpoC 762380 c.-990T>C upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762410 c.-960T>C upstream_gene_variant 1.0 rifampicin
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762434 c.-936T>C upstream_gene_variant 1.0 rifampicin
rpoC 762443 c.-927G>C upstream_gene_variant 1.0 rifampicin
rpoB 762449 c.2643C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 762507 c.2701_2703delCTTinsAG frameshift_variant&missense_variant 0.97 rifampicin
rpoB 762510 p.Ala902Pro missense_variant 0.97 rifampicin Uncertain significance
rpoC 762533 c.-837T>C upstream_gene_variant 0.95 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.95 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.95 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.94 rifampicin
rpoC 762557 c.-813G>C upstream_gene_variant 0.93 rifampicin
rpoC 762560 c.-810A>T upstream_gene_variant 0.93 rifampicin
rpoC 762563 c.-807G>T upstream_gene_variant 0.93 rifampicin
rpoC 762854 c.-516G>C upstream_gene_variant 1.0 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762863 c.3057T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762879 p.Met1025Leu missense_variant 1.0 rifampicin Uncertain significance
rpoC 762896 c.-474G>C upstream_gene_variant 1.0 rifampicin
rpoB 762899 c.3093G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762917 c.3111C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762923 c.3117C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762959 c.3153G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762962 c.3156C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762983 c.-387C>T upstream_gene_variant 1.0 rifampicin
rpoB 762989 c.3183G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763034 c.-336C>T upstream_gene_variant 0.97 rifampicin
rpoB 763053 c.3247_3249delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763076 c.-294C>G upstream_gene_variant 1.0 rifampicin
rpoC 763079 c.-291C>G upstream_gene_variant 1.0 rifampicin
rpoB 763082 c.3276C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763103 c.-267G>C upstream_gene_variant 1.0 rifampicin
rpoB 763115 c.3309T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763130 c.3324G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763133 c.-237G>C upstream_gene_variant 1.0 rifampicin
rpoB 763136 c.3330C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763142 c.-228C>G upstream_gene_variant 1.0 rifampicin
rpoC 763160 c.-210G>T upstream_gene_variant 1.0 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763169 c.-201A>G upstream_gene_variant 1.0 rifampicin
rpoC 763181 c.-189G>C upstream_gene_variant 1.0 rifampicin
rpoC 763187 c.-183C>G upstream_gene_variant 1.0 rifampicin
rpoC 763202 c.-168A>G upstream_gene_variant 1.0 rifampicin
rpoC 763205 c.-165G>C upstream_gene_variant 1.0 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCG upstream_gene_variant 1.0 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763227 p.Leu1141Met missense_variant 1.0 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 1.0 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 1.0 rifampicin
rpoB 763241 p.Glu1145Asp missense_variant 1.0 rifampicin
rpoC 763375 c.6C>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763411 c.42T>C synonymous_variant 1.0 rifampicin
rpoC 763414 c.45T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763423 p.Glu18Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 763430 c.61_63delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763433 c.64_66delCAAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 1.0 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763495 c.126G>A synonymous_variant 1.0 rifampicin
rpoC 763528 c.159G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763531 c.162G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763633 c.264T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763696 c.327T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763699 c.330G>C synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763708 c.339G>C synonymous_variant 1.0 rifampicin
rpoC 763709 c.340C>T synonymous_variant 1.0 rifampicin
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 0.97 rifampicin
rpoC 763747 c.378G>A synonymous_variant 0.96 rifampicin
rpoC 763765 c.396T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763781 p.Ser138Ala missense_variant 0.96 rifampicin
rpoC 763790 p.Glu141Thr missense_variant 0.95 rifampicin
rpoC 763795 p.Glu142Asp missense_variant 0.95 rifampicin
rpoC 763807 c.438T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 0.94 rifampicin
rpoC 763822 c.453C>G synonymous_variant 0.92 rifampicin
rpoC 763825 c.456G>A synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 763836 p.Ala156Val missense_variant 0.92 rifampicin
rpoC 763840 c.471G>C synonymous_variant 0.92 rifampicin
rpoC 763844 p.Arg159Lys missense_variant 0.92 rifampicin
rpoC 763858 c.489A>G synonymous_variant 0.92 rifampicin
rpoC 763860 p.Asp164Ala missense_variant 0.93 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 0.94 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>T synonymous_variant 1.0 rifampicin
rpoC 763891 c.522G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763903 c.534G>A synonymous_variant 1.0 rifampicin
rpoC 763925 p.Ala186Arg missense_variant 1.0 rifampicin
rpoC 763930 p.Glu187Asp missense_variant 1.0 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 763945 c.576T>C synonymous_variant 1.0 rifampicin
rpoC 763947 p.Ala193Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763969 c.600C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 1.0 rifampicin
rpoC 763987 c.618C>T synonymous_variant 1.0 rifampicin
rpoC 763991 c.622_624delATCinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764011 c.642T>C synonymous_variant 1.0 rifampicin
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 0.95 rifampicin
rpoC 764029 p.Glu220Asp missense_variant 0.95 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 0.95 rifampicin
rpoC 764040 p.Ser224Thr missense_variant 0.97 rifampicin
rpoC 764044 c.675T>C synonymous_variant 0.97 rifampicin
rpoC 764059 c.690G>T synonymous_variant 0.97 rifampicin
rpoC 764071 c.702G>C synonymous_variant 0.97 rifampicin
rpoC 764077 c.708C>G synonymous_variant 0.97 rifampicin
rpoC 764083 c.714A>G synonymous_variant 0.97 rifampicin
rpoC 764084 p.Asn239Val missense_variant 0.97 rifampicin
rpoC 764098 c.729A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764126 p.Thr253Glu missense_variant 0.96 rifampicin
rpoC 764131 c.762T>C synonymous_variant 0.96 rifampicin
rpoC 764132 p.Ala255Ser missense_variant 0.96 rifampicin
rpoC 764143 c.774G>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 764153 p.Gln262Lys missense_variant 0.96 rifampicin
rpoC 764161 c.792G>C synonymous_variant 0.96 rifampicin
rpoC 764169 p.Asn267Thr missense_variant 1.0 rifampicin
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 764213 p.Arg282Lys missense_variant 1.0 rifampicin Uncertain significance
rpoC 764227 c.858G>C synonymous_variant 1.0 rifampicin
rpoC 764239 c.870T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764242 c.873C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 1.0 rifampicin
rpoC 764257 c.888G>C synonymous_variant 1.0 rifampicin
rpoC 764263 c.894G>C synonymous_variant 1.0 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.95 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764377 c.1008C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018_1020delTTGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764395 c.1026C>T synonymous_variant 0.97 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764410 c.1041G>C synonymous_variant 0.97 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764435 c.1066_1068delAGGinsCA frameshift_variant&missense_variant 0.97 rifampicin
rpoC 764452 c.1083T>C synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>G synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764530 c.1161C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>C synonymous_variant 1.0 rifampicin
rpoC 764575 c.1206T>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 0.98 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 0.98 rifampicin
rpoC 764605 c.1236G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764611 c.1242G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764626 c.1257C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764662 c.1293G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764677 c.1308C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 0.98 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764719 c.1350G>A synonymous_variant 0.98 rifampicin
rpoC 764746 c.1377G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764800 c.1431G>A synonymous_variant 1.0 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 1.0 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>T synonymous_variant 0.98 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.97 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764911 c.1542A>G synonymous_variant 0.97 rifampicin
rpoC 764912 p.Met515Gln missense_variant 0.97 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.97 rifampicin
rpoC 764948 c.1579T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>C synonymous_variant 0.96 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.95 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.95 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765040 c.1671T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 765070 c.1701G>T synonymous_variant 0.92 rifampicin
rpoC 765379 c.2010G>T synonymous_variant 1.0 rifampicin
rpoC 765383 c.2014_2016delATGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 765403 c.2034G>C synonymous_variant 1.0 rifampicin
rpoC 765404 p.Leu679Lys missense_variant 1.0 rifampicin
rpoC 765409 c.2040T>C synonymous_variant 1.0 rifampicin
rpoC 765412 c.2043T>C synonymous_variant 1.0 rifampicin
rpoC 765425 p.Lys686Ala missense_variant 0.94 rifampicin
rpoC 765434 p.His689Phe missense_variant 0.94 rifampicin
rpoC 765444 p.Val692Ala missense_variant 0.95 rifampicin Uncertain significance
rpoC 765454 c.2085C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765466 c.2097C>T synonymous_variant 0.95 rifampicin
rpoC 765469 c.2100G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765493 c.2124G>C synonymous_variant 0.95 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765508 c.2139C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 765841 c.2472G>C synonymous_variant 0.85 rifampicin
rpoC 765861 p.Phe831Tyr missense_variant 0.94 rifampicin Uncertain significance
rpoC 765875 p.Val836Ile missense_variant 0.95 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 0.95 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765934 c.2565C>T synonymous_variant 0.96 rifampicin
rpoC 765937 c.2568T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765940 c.2571A>T synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 0.95 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765952 c.2583G>C synonymous_variant 0.96 rifampicin
rpoC 765961 c.2592G>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593T>C synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766690 c.3321G>C synonymous_variant 1.0 rifampicin
rpoC 766693 c.3324C>G synonymous_variant 1.0 rifampicin
rpoC 766702 c.3333G>C synonymous_variant 1.0 rifampicin
rpoC 766711 c.3342C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766712 c.3343_3345delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766747 c.3378C>T synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766777 c.3408C>G synonymous_variant 1.0 rifampicin
rpoC 766798 c.3429C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766807 c.3438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766876 c.3507C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766883 c.3514_3516delTCGinsGA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766894 c.3525T>C synonymous_variant 1.0 rifampicin
rpoC 766895 c.3526T>C synonymous_variant 1.0 rifampicin
rpoC 766900 c.3531T>C synonymous_variant 1.0 rifampicin
rpoC 766909 c.3540G>C synonymous_variant 1.0 rifampicin
rpoC 766911 p.Ile1181Thr missense_variant 1.0 rifampicin
rpoC 766915 p.Asp1182Glu missense_variant 1.0 rifampicin
rpoC 766921 c.3552G>C synonymous_variant 1.0 rifampicin
rpoC 766931 c.3562_3564delGCAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766935 p.Glu1189Ala missense_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766948 c.3579G>T synonymous_variant 1.0 rifampicin
rpoC 766951 c.3582G>C synonymous_variant 1.0 rifampicin
rpoC 766961 p.Gly1198Asn missense_variant 1.0 rifampicin
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767059 c.3690T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767105 c.3736_3738delAACinsCG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767167 c.3798C>T synonymous_variant 1.0 rifampicin
rpoC 767173 c.3804C>A synonymous_variant 1.0 rifampicin
rpoC 767174 p.Asn1269His missense_variant 1.0 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 1.0 rifampicin
rpoC 767191 c.3822C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767197 c.3828G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>C synonymous_variant 1.0 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
mmpL5 775814 c.2667C>G synonymous_variant 0.78 clofazimine
bedaquiline
mmpL5 775817 c.2664T>C synonymous_variant 0.96 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775826 c.2655G>T synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775832 c.2647_2649delGCCinsTA frameshift_variant&missense_variant 0.39 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775835 c.2646C>G synonymous_variant 0.47 clofazimine
bedaquiline
mmpL5 775847 c.2634G>T synonymous_variant 0.86 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mmpL5 775851 p.Ser877Thr missense_variant 0.68 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775862 c.2619G>C synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 0.97 clofazimine
bedaquiline
mmpL5 775883 c.2596_2598delATCinsCG frameshift_variant&missense_variant 0.98 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775886 c.2595A>C synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775889 c.2592C>G synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 775901 c.2580G>A synonymous_variant 0.38 clofazimine
bedaquiline
mmpL5 775907 c.2572_2574delCTCinsTG frameshift_variant&synonymous_variant 0.45 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775910 c.2569_2571delCGGinsAA frameshift_variant&missense_variant 0.38 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775916 c.2565T>C synonymous_variant 0.98 clofazimine
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.45 clofazimine
bedaquiline
mmpL5 775949 c.2532G>C synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775955 c.2524_2526delATCinsGG frameshift_variant&missense_variant 0.79 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775961 c.2520C>G synonymous_variant 0.97 clofazimine
bedaquiline
mmpL5 775975 p.Leu836Met missense_variant 0.76 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775982 p.Trp833Phe missense_variant 0.54 clofazimine
bedaquiline
mmpL5 775991 c.2490G>A synonymous_variant 0.68 clofazimine
bedaquiline
mmpL5 776017 p.Ile822Val missense_variant 0.87 clofazimine
bedaquiline
mmpL5 776018 c.2463G>T synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 776021 c.2458_2460delGTGinsAC frameshift_variant&missense_variant 0.87 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776024 c.2457G>C synonymous_variant 0.73 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.85 clofazimine
bedaquiline
mmpL5 776039 c.2442C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776045 c.2436G>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 776048 c.2433G>C synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 776053 p.Leu810Val missense_variant 1.0 clofazimine
bedaquiline
rpsL 781572 c.13_15delCAGinsAC frameshift_variant&missense_variant 0.94 streptomycin Uncertain significance
rpsL 781595 c.36T>C synonymous_variant 0.96 streptomycin
rpsL 781598 c.39G>C synonymous_variant 0.96 streptomycin
rpsL 781605 p.Ile16Val missense_variant 0.96 streptomycin Uncertain significance
rpsL 781608 p.Ser17Ala missense_variant 0.96 streptomycin
rpsL 781616 c.57C>G synonymous_variant 1.0 streptomycin
rpsL 781628 c.69T>C synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781631 c.72G>C synonymous_variant 1.0 streptomycin
rpsL 781652 c.93T>C synonymous_variant 1.0 streptomycin
rpsL 781658 c.99A>G synonymous_variant 1.0 streptomycin
rpsL 781664 c.105C>T synonymous_variant 1.0 streptomycin
rpsL 781682 c.123T>C synonymous_variant 1.0 streptomycin
rpsL 781715 c.156T>C synonymous_variant 1.0 streptomycin
rpsL 781728 c.169T>C synonymous_variant 1.0 streptomycin
rpsL 781735 p.Ser59Thr missense_variant 1.0 streptomycin
rpsL 781737 p.Gln60Gly missense_variant 1.0 streptomycin
rpsL 781742 c.183C>T synonymous_variant 1.0 streptomycin
rpsL 781751 c.192G>C synonymous_variant 1.0 streptomycin
rpsL 781754 c.195G>C synonymous_variant 1.0 streptomycin
rpsL 781760 c.201T>C synonymous_variant 1.0 streptomycin
rpsL 781766 c.207C>T synonymous_variant 1.0 streptomycin Not assoc w R - Interim
rpsL 781769 c.210G>A synonymous_variant 1.0 streptomycin
rpsL 781805 c.246G>C synonymous_variant 1.0 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781829 c.270G>C synonymous_variant 0.97 streptomycin
rpsL 781832 c.273T>G synonymous_variant 0.97 streptomycin
rpsL 781853 c.294C>T synonymous_variant 0.97 streptomycin
rpsL 781859 c.300T>C synonymous_variant 0.97 streptomycin Not assoc w R - Interim
rpsL 781868 c.309T>C synonymous_variant 0.97 streptomycin
rpsL 781871 c.312G>C synonymous_variant 0.97 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.97 streptomycin
rpsL 781901 c.342C>T synonymous_variant 0.96 streptomycin
rpsL 781916 c.357T>G synonymous_variant 0.96 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.95 streptomycin Uncertain significance
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.95 streptomycin
rplC 800537 c.-272C>T upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800564 c.-245C>T upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800579 c.-230C>T upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800585 c.-224T>A upstream_gene_variant 1.0 linezolid
rplC 800588 c.-221C>A upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800639 c.-170C>T upstream_gene_variant 1.0 linezolid
rplC 800645 c.-164C>G upstream_gene_variant 1.0 linezolid
rplC 800648 c.-161A>C upstream_gene_variant 1.0 linezolid
rplC 800651 c.-158G>A upstream_gene_variant 1.0 linezolid
rplC 800678 c.-131C>T upstream_gene_variant 1.0 linezolid
rplC 800684 c.-125G>A upstream_gene_variant 1.0 linezolid
rplC 800690 c.-119C>G upstream_gene_variant 1.0 linezolid
rplC 800693 c.-116A>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>C upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106_-104delTTGinsCT upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800744 c.-65G>C upstream_gene_variant 1.0 linezolid
rplC 800745 c.-64_-62delCTCinsTG upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
fbiC 1303464 c.534A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303470 c.540T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303476 c.546G>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1303479 c.549G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303488 c.558G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303503 c.573G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303521 c.591C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303536 c.606G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303542 c.612C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303548 c.618G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303551 c.621G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 0.93 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304502 c.1572G>C synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304508 p.Glu526Asp missense_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304511 c.1581C>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304532 c.1602G>A synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304544 p.Asp538Glu missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304567 p.Phe546Tyr missense_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 0.96 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304634 c.1704C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304655 c.1725C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304658 c.1728C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304671 p.Val581Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304751 c.1821C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304769 c.1839C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304790 c.1860C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304823 c.1893C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304826 c.1896G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304829 c.1899T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
sigE 1364640 c.228G>C synonymous_variant 0.93 pyrazinamide
sigE 1364667 c.255T>C synonymous_variant 0.95 pyrazinamide
sigE 1364670 c.258G>A synonymous_variant 0.95 pyrazinamide
sigE 1364679 c.267T>C synonymous_variant 0.96 pyrazinamide
sigE 1364685 c.273C>T synonymous_variant 0.96 pyrazinamide
sigE 1364691 c.279T>C synonymous_variant 0.93 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 0.91 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 0.91 pyrazinamide
sigE 1364715 c.303G>C synonymous_variant 0.91 pyrazinamide
sigE 1364719 p.Ser103Ala missense_variant 0.91 pyrazinamide
sigE 1364724 c.312C>T synonymous_variant 0.91 pyrazinamide
sigE 1364733 p.His107Gln missense_variant 0.92 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 0.92 pyrazinamide
sigE 1364760 c.348C>G synonymous_variant 0.95 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 0.95 pyrazinamide
sigE 1364767 c.355A>C synonymous_variant 0.95 pyrazinamide
sigE 1364782 c.370_372delGTCinsCG frameshift_variant&missense_variant 0.95 pyrazinamide Uncertain significance
sigE 1364790 c.378T>C synonymous_variant 0.96 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 0.96 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 0.96 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 0.94 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 0.96 pyrazinamide
sigE 1364856 c.444C>G synonymous_variant 0.98 pyrazinamide
sigE 1364865 c.453G>C synonymous_variant 0.98 pyrazinamide
sigE 1364866 c.454_456delGCTinsAC frameshift_variant&missense_variant 0.98 pyrazinamide Uncertain significance
sigE 1364877 c.465G>C synonymous_variant 0.98 pyrazinamide Not assoc w R - Interim
sigE 1364883 c.471G>A synonymous_variant 0.98 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 0.98 pyrazinamide Uncertain significance
sigE 1364913 c.501C>G synonymous_variant 0.98 pyrazinamide
sigE 1364919 p.Asp169Glu missense_variant 0.98 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 0.98 pyrazinamide
sigE 1364925 c.513C>G synonymous_variant 0.98 pyrazinamide
sigE 1364931 c.519C>G synonymous_variant 0.98 pyrazinamide
sigE 1364950 c.538_540delGCAinsTG frameshift_variant&stop_gained 0.97 pyrazinamide Uncertain significance
sigE 1364961 c.549A>C synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
sigE 1364964 c.552T>G synonymous_variant 0.97 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 1.0 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 1.0 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 1.0 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.94 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.94 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.94 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.92 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.9 pyrazinamide
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472028 n.183A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472031 n.186G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472032 n.187G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472041 n.196C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472042 n.197T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Not assoc w R
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472290 n.445C>A non_coding_transcript_exon_variant 0.95 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472313 n.468delGinsCA non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.94 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472324 n.479G>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472847 n.1002G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472860 n.1015C>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.97 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.93 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.93 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Not assoc w R
capreomycin Not assoc w R
amikacin Not assoc w R
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.95 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473811 n.154C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474287 n.630_635delTCCTTTinsCTCGACTTG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474294 n.638_649delCTCTCCGGAGGA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1673505 c.-697A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673517 c.-685G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673523 c.-679G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673529 c.-673G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673535 c.-667A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673541 c.-661G>A upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673547 c.-655T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673568 c.-634C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673571 c.-631C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673580 c.-622T>C upstream_gene_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1673583 c.-619A>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673589 c.-613A>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673595 c.-607A>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673596 p.Lys53Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673607 c.-595T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673613 c.-589C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673615 p.Glu59Val missense_variant 1.0 ethionamide
isoniazid
inhA 1673622 c.-580C>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673633 p.Ser65Asn missense_variant 1.0 ethionamide
isoniazid
fabG1 1673637 p.Asp66Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673646 c.-556T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673649 c.-553C>G upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1673657 p.Thr73Lys missense_variant 1.0 ethionamide
isoniazid
fabG1 1673660 p.Ala74Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1673664 c.-538A>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673667 c.-535A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1673679 c.-523T>C upstream_gene_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
fabG1 1674006 p.Asp189Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674018 c.-184G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674024 c.-178T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674030 c.-172G>T upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674033 c.-169T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674037 p.Gln200Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674042 c.-160G>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674049 p.Gln204Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674054 c.-148T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674060 c.-142A>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674063 c.-139G>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674075 c.-127C>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674079 p.Pro214Ala missense_variant 1.0 ethionamide
isoniazid
fabG1 1674083 p.Ala215Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674090 c.-112C>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674096 c.-106G>T upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674098 p.Val220Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674123 c.-79T>C upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674126 c.-76G>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674127 p.Ser230Gly missense_variant 1.0 ethionamide
isoniazid
inhA 1674132 c.-70T>C upstream_gene_variant 1.0 ethionamide
isoniazid
fabG1 1674136 p.Ser233Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674141 c.-61T>G upstream_gene_variant 1.0 ethionamide
isoniazid
inhA 1674531 c.330C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674534 c.333G>C synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674540 c.339C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674546 c.345T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674570 c.369G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674708 c.507G>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674714 c.513C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674726 c.525G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674741 c.540C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674742 p.Lys181Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674746 p.Tyr182Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674762 c.561T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674771 c.570C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
rpsA 1833578 p.Val13Ile missense_variant 1.0 pyrazinamide
rpsA 1833589 c.48A>T synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833596 p.Ser19Ala missense_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833625 c.84A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833703 c.162C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833739 c.198C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833742 c.201A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833760 c.219C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833802 c.261A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833808 c.267G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833811 c.270G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 0.96 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 0.96 pyrazinamide
rpsA 1833838 c.297G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 0.96 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 0.97 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 0.97 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 0.97 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 1.0 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833991 c.450C>A synonymous_variant 1.0 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834012 c.471G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834069 c.528G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834096 c.555G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834099 c.558C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 0.97 pyrazinamide
rpsA 1834108 c.567C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834135 c.594G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 0.96 pyrazinamide
rpsA 1834153 c.612_613delTAinsCCAGCTC frameshift_variant&missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1834157 c.616_621delTTGCAAinsC frameshift_variant&synonymous_variant 0.96 pyrazinamide Uncertain significance
rpsA 1834165 c.624A>G synonymous_variant 0.96 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 0.96 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
rpsA 1834213 c.672G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834279 c.738C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834298 p.Gln253Thr missense_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834361 c.820T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834417 c.876G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834483 c.942G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 1.0 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834540 c.999G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834543 c.1002C>G synonymous_variant 0.95 pyrazinamide
rpsA 1834546 c.1005T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834552 c.1011G>T synonymous_variant 1.0 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 1.0 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834666 c.1125G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834667 p.Ala376Ser missense_variant 1.0 pyrazinamide
rpsA 1834690 c.1149T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834700 p.Gln387Ala missense_variant 1.0 pyrazinamide
rpsA 1834705 c.1164C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834738 p.Glu399Asp missense_variant 1.0 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834759 c.1218A>C synonymous_variant 0.98 pyrazinamide
rpsA 1834765 p.Glu408Asp missense_variant 1.0 pyrazinamide
rpsA 1834775 p.Ala412Thr missense_variant 1.0 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834810 c.1269C>T synonymous_variant 1.0 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236_-234delGCAinsTC upstream_gene_variant 1.0 linezolid
tsnR 1853375 c.-231G>C upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>T upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853417 c.-189G>C upstream_gene_variant 0.94 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 0.94 linezolid
tsnR 1853429 c.-177G>C upstream_gene_variant 0.93 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 0.93 linezolid
tsnR 1853444 c.-162C>T upstream_gene_variant 0.92 linezolid
ndh 2102860 c.183G>C synonymous_variant 0.9 ethionamide Not assoc w R - Interim
delamanid
isoniazid Not assoc w R - Interim
ndh 2102899 c.144T>C synonymous_variant 0.9 ethionamide
delamanid
isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 1.0 isoniazid
kasA 2517965 c.-150C>G upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 1.0 isoniazid
kasA 2517993 c.-122G>T upstream_gene_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518534 c.420G>C synonymous_variant 1.0 isoniazid
kasA 2518564 c.450C>T synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518570 c.456G>C synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>C synonymous_variant 1.0 isoniazid
kasA 2518582 c.468G>C synonymous_variant 1.0 isoniazid
kasA 2518583 p.Gln157Glu missense_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>T synonymous_variant 1.0 isoniazid
kasA 2518606 c.492G>C synonymous_variant 1.0 isoniazid
kasA 2518609 p.Met165Ile missense_variant 1.0 isoniazid
kasA 2518612 c.498C>G synonymous_variant 1.0 isoniazid
kasA 2518630 c.516G>C synonymous_variant 1.0 isoniazid
kasA 2518636 c.522C>T synonymous_variant 1.0 isoniazid
kasA 2518644 p.Ala177Gly missense_variant 1.0 isoniazid
kasA 2518651 c.537C>A synonymous_variant 1.0 isoniazid
kasA 2518657 c.543G>A synonymous_variant 1.0 isoniazid
kasA 2518672 c.558G>C synonymous_variant 1.0 isoniazid
kasA 2518678 c.564C>T synonymous_variant 1.0 isoniazid
kasA 2518687 c.573C>T synonymous_variant 1.0 isoniazid
kasA 2518688 p.Val192Ile missense_variant 1.0 isoniazid
kasA 2518696 c.582C>G synonymous_variant 1.0 isoniazid
kasA 2518702 c.588C>T synonymous_variant 1.0 isoniazid
kasA 2518711 c.597A>G synonymous_variant 1.0 isoniazid
kasA 2518714 c.600A>T synonymous_variant 1.0 isoniazid
kasA 2518715 p.Pro201Ala missense_variant 1.0 isoniazid
kasA 2518747 c.633C>G synonymous_variant 1.0 isoniazid
kasA 2518756 c.642G>T synonymous_variant 1.0 isoniazid
kasA 2518759 c.645C>G synonymous_variant 1.0 isoniazid
kasA 2518780 p.Glu222Asp missense_variant 1.0 isoniazid
kasA 2518783 c.669T>G synonymous_variant 0.96 isoniazid
kasA 2518786 c.672G>A synonymous_variant 1.0 isoniazid
kasA 2518787 c.673_675delCGGinsGT frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518792 c.678C>T synonymous_variant 1.0 isoniazid
kasA 2518795 c.681C>G synonymous_variant 1.0 isoniazid
kasA 2518798 c.684G>T synonymous_variant 1.0 isoniazid
kasA 2518811 c.697_699delGACinsAT frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518822 c.708C>G synonymous_variant 1.0 isoniazid
kasA 2518825 c.711T>C synonymous_variant 1.0 isoniazid
kasA 2518828 c.714G>C synonymous_variant 1.0 isoniazid
kasA 2518849 c.735G>C synonymous_variant 1.0 isoniazid
kasA 2518853 p.Leu247Val missense_variant 1.0 isoniazid
kasA 2518864 c.750G>C synonymous_variant 1.0 isoniazid
kasA 2518877 p.Lys255Leu missense_variant 1.0 isoniazid
kasA 2518885 c.771T>C synonymous_variant 1.0 isoniazid
Rv2477c 2782528 c.1515G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782537 c.1506T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782540 c.1503T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782960 c.1083C>G synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782966 c.1077C>T synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782969 c.1074A>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782972 c.1071G>C synonymous_variant 0.9 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782981 c.1062G>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782984 c.1059T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782987 c.1056C>G synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2782990 c.1053C>T synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783002 c.1041T>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783008 c.1035C>A synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783013 c.1030T>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783014 p.Ser343Thr missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783020 c.1023G>C synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783047 p.Asp332Glu missense_variant 0.94 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 0.94 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783083 c.960G>C synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783086 p.Asn319Ser missense_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783128 c.915C>T synonymous_variant 0.91 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783371 c.672A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783410 c.633G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783419 c.624G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783422 c.621T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783425 p.Pro206Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783432 p.Ser204Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783440 c.603T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783456 p.Gln196Met missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783461 c.582T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783464 c.579A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783467 c.576G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783473 c.570A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783485 c.558G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783499 c.544T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783502 c.541T>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783593 c.450T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783605 c.438T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783611 c.432C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783620 c.421_423delCTCinsTG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783626 c.415_417delGCGinsTC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783634 p.Leu137Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783641 c.402G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783651 p.His131Ala missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783659 c.384A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783662 c.381G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783665 c.378A>G synonymous_variant 0.92 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783672 p.Arg124Gln missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783674 c.369T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783683 c.360A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783689 c.354G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783695 c.348C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783718 c.325T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859735 c.684G>C synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859747 c.672C>G synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859750 c.669C>G synonymous_variant 0.92 clofazimine
bedaquiline
pepQ 2859771 c.648T>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859774 c.645C>T synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859778 p.Val214Asp missense_variant 0.93 clofazimine
bedaquiline
pepQ 2859780 p.Gln213Ala missense_variant 0.93 clofazimine
bedaquiline
pepQ 2859786 c.633G>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859792 c.627C>T synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859798 c.621G>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859804 c.615C>T synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859828 c.591G>C synonymous_variant 0.93 clofazimine
bedaquiline
pepQ 2859833 p.Ala196Thr missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859834 c.585T>C synonymous_variant 1.0 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
pepQ 2859852 c.567A>C synonymous_variant 1.0 clofazimine
bedaquiline
Rv2752c 3063370 c.1671_*1144del frameshift_variant&stop_lost&splice_region_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065025 c.1167G>T synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065048 c.1144C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065070 c.1122C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065073 c.1119C>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065079 c.1113T>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065085 c.1105_1107delAGGinsCT frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065088 c.1104A>G synonymous_variant 0.92 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065091 c.1101A>G synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065094 c.1098C>G synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065097 c.1095C>T synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065106 c.1086C>G synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065109 c.1081_1083delAGAinsCG frameshift_variant&missense_variant 0.92 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065120 p.Ile358Val missense_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065130 c.1062A>G synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065133 c.1059T>C synonymous_variant 0.94 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065142 c.1050A>C synonymous_variant 0.95 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065151 c.1041G>C synonymous_variant 0.95 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065172 c.1020G>C synonymous_variant 0.93 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065178 c.1014G>C synonymous_variant 0.92 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065181 c.1011G>C synonymous_variant 0.91 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065186 c.1006T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065187 c.1003_1005delGTGinsAC frameshift_variant&missense_variant 0.9 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065193 c.999C>G synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065199 c.993T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065202 c.990T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065205 c.987T>C synonymous_variant 0.9 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065229 c.963G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065232 c.960T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065241 c.951A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065249 c.943T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065900 p.Pro98Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065901 c.291A>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065917 p.Phe92His missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065922 c.270T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065925 c.267G>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065928 c.264G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065947 p.Gly82Ala missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065955 c.235_237delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065979 c.213T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065982 c.210G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
Rv2752c 3065987 p.Asp69Asn missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065988 c.204A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3065993 p.Val67Ile missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
levofloxacin
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3065994 c.198T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066002 p.Met64Leu missense_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066018 c.174T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066024 c.168T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066039 c.153C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066042 c.150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066045 c.147T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066050 c.142T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066051 c.141G>A synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066054 c.138T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066066 c.126T>C synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066069 c.121_123delTTGinsCC frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
Rv2752c 3066075 c.117A>G synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066084 c.108C>T synonymous_variant 1.0 ethambutol
moxifloxacin
levofloxacin
rifampicin
isoniazid
Rv2752c 3066087 c.105A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
thyA 3073881 c.591C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073887 p.Ser195Gly missense_variant 1.0 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073920 c.552C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073953 c.519T>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073959 c.513T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073968 c.504C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073983 c.489C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073993 c.478_479delAGinsTC synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073999 p.Arg158Lys missense_variant 1.0 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074034 c.438T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074046 c.426G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 1.0 para-aminosalicylic_acid
mtrB 3625222 c.1392T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625240 c.-330T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625243 c.-333T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625255 c.-345T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625263 p.Tyr451His missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625264 c.1350C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3625267 c.1347T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625270 c.-360G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625279 c.-369C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625282 c.-372C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625291 c.-381A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625313 p.Arg434Glu missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625336 c.-426C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625345 c.-435T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625351 c.1263T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625558 c.-648C>T upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3625562 p.Asn351Ala missense_variant 0.91 bedaquiline
rifampicin
lpqB 3625564 c.-654C>G upstream_gene_variant 0.91 bedaquiline
rifampicin
mtrB 3625569 c.1045T>C synonymous_variant 0.92 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625579 c.-669A>G upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625585 c.-675G>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625588 c.-678G>A upstream_gene_variant 0.93 bedaquiline
rifampicin
mtrB 3625592 p.Ser341Asn missense_variant 0.93 bedaquiline
rifampicin
lpqB 3625594 c.-684T>C upstream_gene_variant 0.93 bedaquiline
rifampicin
lpqB 3625615 c.-705G>C upstream_gene_variant 0.95 bedaquiline
rifampicin
mtrB 3625623 p.Thr331Ala missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625624 c.-714C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625630 c.-720C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625636 p.Ala326Glu missense_variant 1.0 bedaquiline
rifampicin
mtrB 3625648 c.964_966delTATinsCC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625656 c.958T>C synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625675 c.-765G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625687 c.-777G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625690 c.-780T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625696 c.-786A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625699 c.915C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3625750 c.862_864delCAGinsAC frameshift_variant&missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625755 p.Ala287Thr missense_variant 1.0 bedaquiline
rifampicin Uncertain significance
lpqB 3625762 c.-852A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625806 c.808A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625822 c.-912C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625837 c.777C>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
lpqB 3625840 c.-930A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3625845 p.Ser257Thr missense_variant 1.0 bedaquiline
rifampicin
lpqB 3625864 c.-954T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
lpqB 3625879 c.-969G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626705 c.-92G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626711 p.Thr213Gln missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626723 c.-110C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626726 c.-113T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626729 p.Lys207Thr missense_variant 1.0 bedaquiline
rifampicin
mtrB 3626732 c.-119A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626749 c.601C>T synonymous_variant 1.0 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
mtrB 3626750 c.-137T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626773 c.-160C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626776 c.-163A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3626786 c.564A>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrA 3626789 c.561C>T synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3626792 c.-179G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626798 c.-185T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626804 c.-191A>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626810 c.-197A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626831 c.-218T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626972 c.-359A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626987 c.-374C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3626996 c.-383G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627002 c.-389G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627008 c.-395G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627011 c.-398T>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627017 c.-404G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627041 c.307_309delATCinsGG frameshift_variant&missense_variant 1.0 bedaquiline
rifampicin
mtrB 3627059 c.-446G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627062 c.-449G>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627068 c.282T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627074 c.-461G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627080 c.270T>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627083 c.-470G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627098 c.252A>C synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627104 c.-491C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrA 3627119 c.231T>G synonymous_variant 1.0 bedaquiline
rifampicin Not assoc w R - Interim
mtrB 3627122 c.-509T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627128 c.-515T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627139 c.-526T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627143 c.-530G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627167 c.-554T>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627170 c.-557C>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627242 c.-629C>A upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627251 c.-638G>C upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627263 c.-650C>T upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627266 c.-653A>G upstream_gene_variant 1.0 bedaquiline
rifampicin
mtrB 3627272 c.-659G>T upstream_gene_variant 1.0 bedaquiline
rifampicin
rpoA 3877584 c.924C>G synonymous_variant 1.0 rifampicin
rpoA 3877587 c.921A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877593 c.915C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877596 c.912G>C synonymous_variant 1.0 rifampicin
rpoA 3877602 c.906C>T synonymous_variant 1.0 rifampicin
rpoA 3877617 c.891G>C synonymous_variant 1.0 rifampicin
rpoA 3877638 c.870T>G synonymous_variant 1.0 rifampicin
rpoA 3877656 c.852T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877662 c.846C>T synonymous_variant 1.0 rifampicin
rpoA 3877668 c.840A>G synonymous_variant 1.0 rifampicin
rpoA 3877674 c.834C>T synonymous_variant 1.0 rifampicin
rpoA 3877679 p.Ala277Ser missense_variant 1.0 rifampicin
rpoA 3877686 c.822A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877692 c.816G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877704 c.804G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877728 c.780C>G synonymous_variant 1.0 rifampicin
rpoA 3877734 c.774G>C synonymous_variant 1.0 rifampicin
rpoA 3877737 c.771G>C synonymous_variant 1.0 rifampicin
rpoA 3877743 c.765T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877749 c.759C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877758 c.750G>C synonymous_variant 1.0 rifampicin
rpoA 3877764 c.744C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877770 c.738A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877773 c.735G>C synonymous_variant 1.0 rifampicin
rpoA 3877776 c.732T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877785 c.723C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877836 c.672A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877839 c.669G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877848 c.660C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877856 c.652T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877857 c.651G>A synonymous_variant 1.0 rifampicin
rpoA 3877860 c.648C>T synonymous_variant 0.97 rifampicin
rpoA 3877872 c.636C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoA 3877875 c.633T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877881 c.627G>C synonymous_variant 1.0 rifampicin
rpoA 3877887 c.621G>C synonymous_variant 1.0 rifampicin
rpoA 3877893 c.615C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877900 p.Ser203Thr missense_variant 1.0 rifampicin
rpoA 3877905 c.603A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877920 c.588G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877923 c.585C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877926 c.582G>C synonymous_variant 1.0 rifampicin
rpoA 3877934 c.574C>T synonymous_variant 1.0 rifampicin
rpoA 3877962 c.546G>C synonymous_variant 1.0 rifampicin
rpoA 3877971 p.Asp179Glu missense_variant 1.0 rifampicin Uncertain significance
rpoA 3877986 c.522G>C synonymous_variant 1.0 rifampicin
rpoA 3877989 c.519A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3877995 c.513G>C synonymous_variant 1.0 rifampicin
rpoA 3878001 c.507A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878157 c.351C>G synonymous_variant 1.0 rifampicin
rpoA 3878160 c.348C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878184 c.324C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878193 c.315T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878197 p.Glu104Ala missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878205 c.303T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878217 c.291A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878244 c.264G>A synonymous_variant 1.0 rifampicin
rpoA 3878256 c.252G>C synonymous_variant 1.0 rifampicin
rpoA 3878262 c.244_246delAGCinsGT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoA 3878271 c.237T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878283 p.Glu75Asp missense_variant 1.0 rifampicin Uncertain significance
rpoA 3878292 c.216T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878298 c.210A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878301 c.207C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878310 c.198G>C synonymous_variant 1.0 rifampicin
rpoA 3878313 c.195G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878322 c.186A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878331 c.177A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoA 3878337 c.171T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
clpC1 4038551 c.2154C>G synonymous_variant 0.85 pyrazinamide
clpC1 4038587 c.2118C>T synonymous_variant 0.93 pyrazinamide
clpC1 4038596 c.2109A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038605 c.2100G>A synonymous_variant 0.94 pyrazinamide
clpC1 4038613 p.Asn698His missense_variant 0.94 pyrazinamide
clpC1 4038614 c.2091C>T synonymous_variant 0.94 pyrazinamide
clpC1 4038620 p.Gln695Leu missense_variant 0.94 pyrazinamide
clpC1 4038623 c.2082A>G synonymous_variant 0.94 pyrazinamide
clpC1 4038640 p.Asp689Asn missense_variant 0.95 pyrazinamide
clpC1 4038647 c.2058T>G synonymous_variant 0.96 pyrazinamide
clpC1 4038658 p.Lys683Gln missense_variant 0.94 pyrazinamide
clpC1 4038661 p.Ser682Thr missense_variant 1.0 pyrazinamide
clpC1 4038662 c.2043T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038671 c.2034T>A synonymous_variant 1.0 pyrazinamide
clpC1 4038677 c.2026_2028delCCGinsGT frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4038683 c.2022T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038701 c.2004G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038704 c.2001T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038707 c.1998C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038710 c.1995G>C synonymous_variant 0.92 pyrazinamide
clpC1 4038713 c.1992T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038721 c.1984C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038740 c.1965G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038749 c.1956C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038755 c.1950G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038773 c.1932T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038779 c.1926C>G synonymous_variant 1.0 pyrazinamide
clpC1 4038782 c.1923G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038790 c.1915C>T synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4038794 p.Ser637Thr missense_variant 0.92 pyrazinamide
clpC1 4038812 c.1893T>C synonymous_variant 0.94 pyrazinamide
clpC1 4038815 c.1890G>C synonymous_variant 0.95 pyrazinamide
clpC1 4038830 c.1875C>T synonymous_variant 0.94 pyrazinamide
clpC1 4038836 c.1869G>C synonymous_variant 0.94 pyrazinamide
clpC1 4038839 c.1866G>T synonymous_variant 0.93 pyrazinamide
clpC1 4038842 c.1863G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038845 c.1860G>T synonymous_variant 0.94 pyrazinamide
clpC1 4038857 c.1846_1848delCGCinsAG frameshift_variant&missense_variant 0.93 pyrazinamide
clpC1 4038860 c.1843_1845delCGGinsAA frameshift_variant&missense_variant 0.93 pyrazinamide
clpC1 4038878 c.1827A>G synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4038905 c.1800A>C synonymous_variant 0.96 pyrazinamide
clpC1 4038908 c.1797C>G synonymous_variant 0.96 pyrazinamide
clpC1 4038911 c.1794G>T synonymous_variant 0.96 pyrazinamide
clpC1 4038914 c.1791G>C synonymous_variant 0.96 pyrazinamide
clpC1 4038917 c.1788C>T synonymous_variant 0.96 pyrazinamide
clpC1 4038923 c.1782A>G synonymous_variant 0.96 pyrazinamide
clpC1 4038941 c.1764G>C synonymous_variant 1.0 pyrazinamide
clpC1 4038953 c.1752A>G synonymous_variant 1.0 pyrazinamide
clpC1 4038956 c.1749T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038965 c.1740T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038971 c.1734T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038974 c.1731T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4038980 c.1725C>T synonymous_variant 1.0 pyrazinamide
clpC1 4038989 c.1716T>C synonymous_variant 1.0 pyrazinamide
clpC1 4038997 c.1708T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039001 p.Asn568Ala missense_variant 1.0 pyrazinamide
clpC1 4039022 c.1683A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039064 c.1641C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039067 c.1638G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039073 c.1632C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039079 c.1626C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039085 c.1620A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039091 c.1614G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039097 c.1608G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039112 c.1593C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039121 c.1584T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039142 c.1563A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039145 c.1560G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039169 p.Glu512Asp missense_variant 1.0 pyrazinamide
clpC1 4039183 c.1522T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039187 c.1518G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039208 c.1497C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039274 c.1431G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039286 c.1419T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039292 c.1413C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039295 c.1410A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039298 c.1407T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039310 c.1395A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039313 c.1392C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039319 c.1386T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039322 c.1383T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039328 c.1377A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039337 p.Thr456Gln missense_variant 1.0 pyrazinamide
clpC1 4039346 c.1359G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039352 c.1353C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039359 p.Ser449Asn missense_variant 1.0 pyrazinamide
clpC1 4039382 c.1323C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039385 c.1320C>T synonymous_variant 1.0 pyrazinamide
clpC1 4039391 c.1314T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039394 c.1311G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039397 c.1308A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039409 c.1296T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039412 c.1293T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039415 p.Glu430Asp missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039430 c.1275T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039436 c.1269G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039442 c.1263A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039448 c.1257A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039466 c.1239T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039469 c.1236T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039472 c.1233G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039481 c.1224T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039484 c.1221T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039487 c.1218G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039517 c.1188C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039556 c.1149G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039570 p.Met379Leu missense_variant 1.0 pyrazinamide Uncertain significance
clpC1 4039571 c.1134G>A synonymous_variant 1.0 pyrazinamide
clpC1 4039574 p.Ala377Gly missense_variant 1.0 pyrazinamide
clpC1 4039577 c.1128T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4039586 c.1119G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039604 c.1101G>A synonymous_variant 0.98 pyrazinamide
clpC1 4039610 c.1095G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039616 c.1089G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039622 c.1083C>T synonymous_variant 0.97 pyrazinamide
clpC1 4039649 c.1056G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039652 c.1053G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039664 c.1041G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039682 c.1023C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039694 c.1011G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039700 c.1005C>T synonymous_variant 0.97 pyrazinamide Not assoc w R - Interim
clpC1 4039724 c.981A>G synonymous_variant 0.98 pyrazinamide
clpC1 4039733 c.972G>C synonymous_variant 0.98 pyrazinamide
clpC1 4039748 c.957G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039751 c.954A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039757 c.948A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039760 c.945T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039766 c.939T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039769 c.936C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039778 c.927A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4039817 c.888A>T synonymous_variant 1.0 pyrazinamide
clpC1 4039820 c.885T>G synonymous_variant 1.0 pyrazinamide
clpC1 4039823 c.882T>A synonymous_variant 1.0 pyrazinamide
clpC1 4039831 c.874T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039832 c.873C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039850 c.855T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039865 c.840T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039898 c.807C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039904 c.801A>G synonymous_variant 1.0 pyrazinamide
clpC1 4039934 c.771G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039946 c.759A>C synonymous_variant 1.0 pyrazinamide
clpC1 4039949 c.756G>C synonymous_variant 1.0 pyrazinamide
clpC1 4039952 c.753T>C synonymous_variant 1.0 pyrazinamide
clpC1 4039979 c.726C>G synonymous_variant 1.0 pyrazinamide
clpC1 4039991 c.714G>C synonymous_variant 0.98 pyrazinamide
clpC1 4040015 c.690G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040021 c.684A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040024 c.681A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040033 c.672G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040042 c.663C>T synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040057 c.648C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040087 c.618G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 1.0 pyrazinamide
clpC1 4040093 c.612C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040141 c.564C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040144 c.561G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040147 c.558A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040153 c.552A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040159 c.546G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040162 c.543G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040165 c.540G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040171 c.534C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040189 c.516C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040192 c.513C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040195 c.510G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040198 c.505_507delTTGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide
clpC1 4040201 c.504C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040204 c.501G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040207 c.498T>G synonymous_variant 1.0 pyrazinamide
clpC1 4040213 p.Ser164Asn missense_variant 1.0 pyrazinamide
clpC1 4040216 c.489C>T synonymous_variant 1.0 pyrazinamide
clpC1 4040228 c.477G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040234 c.471C>A synonymous_variant 1.0 pyrazinamide
clpC1 4040258 c.447G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040267 c.438A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040273 c.432T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040279 c.426C>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
clpC1 4040291 c.414G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040312 c.393G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040315 c.390G>A synonymous_variant 1.0 pyrazinamide
clpC1 4040324 c.381G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040330 c.375C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040345 c.360C>G synonymous_variant 1.0 pyrazinamide
clpC1 4040348 c.357G>C synonymous_variant 1.0 pyrazinamide
clpC1 4040354 c.351A>G synonymous_variant 1.0 pyrazinamide
clpC1 4040357 c.348T>C synonymous_variant 0.95 pyrazinamide
clpC1 4040363 c.342A>T synonymous_variant 0.95 pyrazinamide
clpC1 4040369 c.336C>G synonymous_variant 0.96 pyrazinamide
clpC1 4040375 c.330G>C synonymous_variant 0.96 pyrazinamide
clpC1 4040380 c.325T>C synonymous_variant 0.96 pyrazinamide
clpC1 4040387 c.318A>G synonymous_variant 0.96 pyrazinamide
clpC1 4040393 c.312G>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040411 c.294T>C synonymous_variant 0.96 pyrazinamide Not assoc w R - Interim
clpC1 4040423 c.282A>G synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040431 c.274T>C synonymous_variant 0.94 pyrazinamide
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.93 pyrazinamide
clpC1 4040435 c.270G>C synonymous_variant 0.93 pyrazinamide
clpC1 4040441 c.264C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040444 c.261C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040450 c.255A>G synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040456 c.249C>T synonymous_variant 0.93 pyrazinamide Not assoc w R - Interim
clpC1 4040459 c.246C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040462 c.243C>G synonymous_variant 0.93 pyrazinamide
clpC1 4040465 c.240T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040471 c.234T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
clpC1 4040480 c.225T>G synonymous_variant 0.95 pyrazinamide
clpC1 4040522 c.183T>C synonymous_variant 0.95 pyrazinamide Not assoc w R - Interim
clpC1 4040531 c.174T>C synonymous_variant 0.93 pyrazinamide
clpC1 4040534 c.171A>G synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040540 c.165G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040543 c.162C>T synonymous_variant 0.92 pyrazinamide
clpC1 4040546 c.159G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040551 c.154T>C synonymous_variant 0.92 pyrazinamide Not assoc w R - Interim
clpC1 4040558 c.147G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040561 c.144A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040564 c.141G>A synonymous_variant 0.92 pyrazinamide
clpC1 4040573 c.132T>A synonymous_variant 0.92 pyrazinamide
clpC1 4040579 c.126A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040582 c.123G>T synonymous_variant 0.92 pyrazinamide
clpC1 4040585 c.120A>G synonymous_variant 0.92 pyrazinamide
clpC1 4040588 c.117T>C synonymous_variant 0.92 pyrazinamide
clpC1 4040594 c.111G>C synonymous_variant 0.92 pyrazinamide
clpC1 4040600 c.103_105delTTAinsCC frameshift_variant&missense_variant 0.92 pyrazinamide
clpC1 4040603 c.102T>G synonymous_variant 0.92 pyrazinamide
clpC1 4040606 c.99T>C synonymous_variant 0.92 pyrazinamide
glpK 4138556 c.1200G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138568 c.1188A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138606 c.1150T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138616 c.1140G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138622 c.1134C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138625 c.1131G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138634 c.1122G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138643 c.1113A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138646 c.1110G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138654 c.1102C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4138661 c.1095T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138670 c.1086G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138676 c.1080T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138681 p.Met359Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138682 c.1074C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138694 p.Pro354Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138703 c.1053C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138714 p.Ala348Ser missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138718 c.1038T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138724 c.1032A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138727 c.1029C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138733 c.1023C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138754 c.1002C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138757 c.997_999delCTAinsTG frameshift_variant&synonymous_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
rifampicin Uncertain significance
isoniazid Uncertain significance
glpK 4138775 c.981C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138781 c.975G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138784 c.972G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138790 c.966G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138802 c.954G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138811 c.945C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138817 c.939T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138822 p.Asn312Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138829 c.927A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4138835 c.921C>T synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin
rifampicin Not assoc w R - Interim
isoniazid Not assoc w R - Interim
glpK 4139553 p.Ala68Val missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139573 c.183C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139603 c.153C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
glpK 4139608 p.Leu50Met missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
rifampicin
isoniazid
embC 4240750 c.888C>T synonymous_variant 1.0 ethambutol Not assoc w R
embC 4240771 c.909G>A synonymous_variant 1.0 ethambutol
embC 4240777 p.Glu305Asp missense_variant 1.0 ethambutol
embC 4240780 c.918T>C synonymous_variant 1.0 ethambutol
embC 4240783 c.921G>C synonymous_variant 1.0 ethambutol
embC 4240786 c.924C>T synonymous_variant 1.0 ethambutol
embC 4240789 c.927T>C synonymous_variant 1.0 ethambutol
embC 4240819 c.957A>G synonymous_variant 0.92 ethambutol
embC 4240822 c.960C>G synonymous_variant 0.92 ethambutol
embC 4240828 c.966G>C synonymous_variant 0.92 ethambutol
embC 4240831 c.969T>G synonymous_variant 0.92 ethambutol
embC 4241039 p.Asp393Asn missense_variant 1.0 ethambutol
embC 4241047 c.1185C>A synonymous_variant 1.0 ethambutol
embC 4241050 c.1188T>G synonymous_variant 1.0 ethambutol
embC 4241053 c.1191G>C synonymous_variant 1.0 ethambutol
embC 4241059 c.1197G>A synonymous_variant 1.0 ethambutol
embC 4241072 c.1210_1212delCTGinsGC frameshift_variant&missense_variant 1.0 ethambutol
embC 4241101 c.1239G>C synonymous_variant 1.0 ethambutol
embC 4241107 c.1245G>C synonymous_variant 1.0 ethambutol
embC 4241109 p.Ala416Gly missense_variant 1.0 ethambutol
embC 4241116 c.1254C>G synonymous_variant 1.0 ethambutol
embA 4242469 c.-763_*2872del transcript_ablation 0.94 ethambutol Uncertain significance
embA 4245772 p.Asn847Thr missense_variant 1.0 ethambutol
embA 4245776 c.2544G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
embA 4245784 p.Thr851Lys missense_variant 1.0 ethambutol
embB 4245806 c.-708G>A upstream_gene_variant 1.0 ethambutol
embA 4245807 c.2575_2577delTTAinsCG frameshift_variant&missense_variant 1.0 ethambutol Uncertain significance
embA 4245820 p.Ser863Thr missense_variant 1.0 ethambutol
embA 4245840 p.Val870Thr missense_variant 1.0 ethambutol
embB 4245845 c.-669T>C upstream_gene_variant 1.0 ethambutol
embA 4245846 p.Ser872Ala missense_variant 1.0 ethambutol
embB 4245854 c.-660C>G upstream_gene_variant 1.0 ethambutol
embA 4245868 p.Ser879Phe missense_variant 1.0 ethambutol
embA 4245873 p.Lys881Glu missense_variant 1.0 ethambutol
embA 4245892 p.Ile887Asn missense_variant 1.0 ethambutol