Run ID: SRR1172310
Sample name:
Date: 2024-10-04T23:29:31.874109
Number of reads: 476816
Percentage reads mapped: 15.51
Median coverage: 5.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: HR-TB
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage3.1.2.2 | East-African-Indian | RD750 | 0.09 |
| lineage4 | Euro-American | None | 0.84 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 0.88 |
| La1.7.1 | M.bovis | None | 0.14 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | katG | p.Ile335Thr | Mutation from literature | |
| p.Ile317Leu | Mutation from literature | |||
| ethambutol | embB | p.Ala356Val | Uncertain significance | Mutation from literature |
| p.Asn399Asp | Mutation from literature | |||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| katG | 2155107 | p.Ile335Thr | missense_variant | 1.0 | isoniazid | Mutation from literature | |
| katG | 2155161 | p.Ile317Leu | missense_variant | 1.0 | isoniazid | Mutation from literature | |
| embB | 4247580 | p.Ala356Val | missense_variant | 1.0 | ethambutol | Uncertain significance | Mutation from literature |
| embB | 4247708 | p.Asn399Asp | missense_variant | 1.0 | ethambutol | Mutation from literature |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| dnaA | 21 | c.21A>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 24 | c.24C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 30 | c.30C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 33 | c.33A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 705 | c.705A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 708 | c.708T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 714 | c.714C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 741 | c.741T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 750 | c.750C>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 756 | c.756T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 771 | c.771A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 777 | c.777A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 792 | c.792C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 795 | c.795A>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 805 | c.805_807delTTGinsCTT | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 819 | c.819C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 822 | c.822A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 828 | c.828T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 831 | c.831A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 837 | c.837A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 840 | c.840G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 846 | c.846T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 849 | c.849A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 852 | c.852G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 876 | c.876C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 885 | c.885T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 891 | c.891C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 897 | c.897A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 903 | c.903C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 936 | c.936C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 939 | c.939C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 942 | c.942C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 945 | c.945G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 975 | c.975G>C | synonymous_variant | 0.8 | isoniazid | |
| dnaA | 984 | c.984T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 990 | c.990A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 996 | c.996A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1008 | c.1008G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1020 | c.1020C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1023 | c.1023C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1024 | c.1024T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1029 | c.1029C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1050 | c.1050G>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1068 | c.1068T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1074 | c.1074C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1078 | c.1078_1080delCTCinsTTG | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1092 | c.1092T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1095 | c.1095C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1104 | c.1104T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1119 | c.1119G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1125 | c.1125G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1197 | c.1197T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1200 | c.1200C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1203 | c.1203T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1215 | c.1215C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1220 | p.Asn407Ser | missense_variant | 1.0 | isoniazid | |
| dnaA | 1230 | c.1230A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1254 | c.1254T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1263 | c.1263C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1266 | c.1266A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1278 | c.1278T>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1287 | c.1287A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1293 | c.1293T>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1299 | c.1299_1302delGCCCinsCCCG | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1311 | c.1311C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1317 | c.1317A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1392 | c.1392A>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1413 | c.1413A>C | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1416 | c.1416C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1428 | c.1428C>G | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1434 | c.1434C>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1437 | c.1437G>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1441 | c.1441C>T | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1446 | c.1446C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1461 | c.1461C>A | synonymous_variant | 1.0 | isoniazid | |
| dnaA | 1467 | c.1467G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| dnaA | 1473 | c.1473T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| gyrB | 5314 | c.75C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 5326 | c.87T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5329 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5338 | c.99C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5341 | c.102T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5344 | c.105C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5359 | c.120C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrB | 5362 | c.123T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5363 | c.124_126delTTAinsCTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5371 | c.132T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 5396 | p.Ala53Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6091 | c.852G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6106 | c.867C>A | synonymous_variant | 0.88 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6115 | c.876A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6122 | p.Ala295Ser | missense_variant | 0.85 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6127 | c.888G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6172 | c.933C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6190 | c.951A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6214 | c.975G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6238 | c.999G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6242 | p.Arg335Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6265 | c.1026C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6280 | c.1041T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6286 | c.1047T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6292 | c.1053G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6298 | c.1059C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6307 | c.1068T>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6316 | c.-986G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6326 | p.Ser363Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6331 | c.-971A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6674 | c.-628_-626delCTTinsTTG | upstream_gene_variant | 0.87 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6733 | c.-569G>A | upstream_gene_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6745 | c.1506T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6751 | c.-551G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6769 | c.-533C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6775 | c.1536G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6787 | c.-515G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6793 | c.1554T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6797 | p.Gly520Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6802 | c.1563G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6811 | c.1572C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6824 | c.1585C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 6911 | p.Asn558His | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 6931 | c.1692A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6949 | c.-353A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6955 | c.-347G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6967 | c.-335T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6970 | c.-332C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6976 | c.-326A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6985 | c.-317C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6994 | c.-308C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 6997 | c.-305G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7023 | p.Leu595Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7048 | c.-254G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7051 | p.Glu604Asp | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7057 | c.1818C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrB | 7060 | c.1821T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7066 | c.-236G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7069 | c.-233C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7075 | c.-227T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7076 | c.-226_-224delCTAinsTTG | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7081 | c.-221T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7093 | c.1854T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7141 | c.-161T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7150 | c.-152G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7153 | c.-149G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrB | 7156 | c.1917C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7174 | c.-128C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7177 | c.-125G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7201 | c.-101G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7213 | c.-89G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7307 | c.6A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7322 | c.21G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7325 | c.24delTinsAGGC | conservative_inframe_insertion&synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7334 | c.33G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7335 | p.Leu12Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7349 | c.48A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7361 | c.60C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7412 | c.111C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7422 | c.121C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7433 | c.132G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7502 | c.201C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7526 | c.225G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7547 | c.246C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7626 | c.325C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7643 | c.342C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7646 | c.345C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7655 | c.354G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7661 | c.360C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7670 | c.369A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7676 | c.375G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7679 | c.378G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7697 | c.396C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7706 | c.405C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7725 | c.424C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7763 | c.462T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7769 | c.468C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7793 | c.492G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7797 | c.496_498delCTAinsTTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7820 | c.519G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7832 | c.531G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7835 | c.534A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7859 | c.558A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7865 | c.564T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7868 | c.567C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8168 | c.867A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8189 | c.888G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8192 | c.891C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8198 | c.897T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8201 | c.900C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8207 | c.906T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8253 | p.Ile318Leu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8267 | c.966G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8270 | c.969G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8283 | p.Ile328Leu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8288 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8294 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8324 | c.1023T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8339 | c.1038A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8340 | p.Ala347Ser | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8360 | c.1059G>A | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8372 | c.1071G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8504 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8516 | c.1215T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8519 | c.1218A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8520 | c.1219C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8531 | c.1230G>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8535 | p.Glu412Gln | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8543 | c.1242C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8546 | c.1245T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8555 | c.1254G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8561 | c.1260A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8585 | c.1284C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8588 | c.1287G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8619 | c.1318T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8624 | c.1323G>T | synonymous_variant | 0.97 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8627 | c.1326C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8633 | c.1332C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8636 | c.1335A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8642 | c.1341A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8655 | p.Ile452Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8672 | c.1371A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8678 | c.1377G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8798 | c.1497C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8810 | c.1509A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8813 | p.Asp504Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8818 | p.Ser506Asn | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 8829 | c.1528T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8840 | c.1539C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8873 | c.1572A>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8888 | c.1587C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8897 | c.1596T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8903 | c.1602T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8915 | c.1614A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 8983 | p.Cys561Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8987 | c.1686C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8990 | c.1689C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8996 | c.1695T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 8998 | p.Leu566Trp | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9003 | c.1702C>T | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9023 | c.1722A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9029 | c.1728T>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9032 | c.1731T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9035 | c.1734G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 9038 | c.1737C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9050 | p.Asp583Glu | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9051 | c.1750T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9062 | c.1761C>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9071 | c.1770G>C | synonymous_variant | 0.94 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9074 | c.1773G>C | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9080 | c.1779G>T | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9089 | c.1788G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9128 | c.1827C>A | synonymous_variant | 0.91 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 0.93 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9147 | p.Gly616Ser | missense_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9153 | p.Thr618Glu | missense_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9161 | c.1860C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9167 | c.1866C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9182 | c.1881T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9183 | p.Arg628Lys | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9197 | c.1896G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9236 | c.1935G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9248 | c.1947G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9266 | c.1965C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9287 | c.1986G>C | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9291 | c.1990C>T | synonymous_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 0.94 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9308 | p.Asp669Glu | missense_variant | 0.93 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9315 | c.2014C>T | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9326 | c.2025G>T | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9338 | c.2037G>A | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9341 | c.2040C>G | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9345 | c.2044A>C | synonymous_variant | 0.96 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9398 | c.2097T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9626 | c.2325T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9629 | c.2328C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9630 | p.Val777Ile | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9635 | c.2334T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9638 | c.2337C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9644 | c.2343T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9650 | c.2349G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9662 | c.2361G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9665 | c.2364A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9668 | c.2367C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9674 | c.2373T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9683 | c.2382G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| fgd1 | 490899 | c.117C>T | synonymous_variant | 0.86 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490905 | c.123T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490911 | c.129T>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490917 | c.135C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490921 | p.Gln47Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490929 | c.147C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490932 | c.150T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490948 | p.Ser56Ala | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490971 | c.189A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490974 | c.192T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490980 | p.Asn66Lys | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490983 | c.201G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490988 | p.Leu69Gln | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490995 | c.213C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 490998 | c.216T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491007 | c.225G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491013 | c.231C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491016 | c.234C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491144 | p.Ala121Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491166 | c.384G>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491168 | p.Phe129Tyr | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491175 | c.393G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491178 | c.396G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491181 | c.399T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491191 | p.Gly137Arg | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fgd1 | 491196 | c.414A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| mshA | 574607 | c.-741G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574610 | c.-738G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574616 | c.-732G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574640 | c.-708G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574646 | c.-702G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574650 | c.-698A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574667 | c.-681G>A | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574673 | c.-675A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574676 | c.-672G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574683 | c.-665T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 574688 | c.-660G>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 574694 | c.-654C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574712 | c.-636A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 574718 | c.-630A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575022 | c.-326C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575034 | c.-314_-312delTTAinsCTG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575042 | c.-306T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575051 | c.-297A>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 575052 | c.-296G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575072 | c.-276G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575075 | c.-273T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 575081 | c.-267A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575087 | c.-261C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575109 | c.-239G>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575114 | c.-234G>A | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 575117 | c.-231T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575118 | c.-230A>G | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| mshA | 575123 | c.-225A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575124 | c.-224_-222delGGGinsCGT | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575144 | c.-204T>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575153 | c.-195C>A | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| mshA | 575161 | c.-187_-186delTTinsCC | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575704 | c.357T>C | synonymous_variant | 0.91 | isoniazid | |
| ethionamide | ||||||
| mshA | 575705 | c.358T>C | synonymous_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| mshA | 575713 | c.366G>A | synonymous_variant | 0.92 | isoniazid | |
| ethionamide | ||||||
| mshA | 575719 | c.372C>T | synonymous_variant | 0.93 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| mshA | 575734 | c.387T>G | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| mshA | 575746 | c.399C>G | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| mshA | 575767 | c.420G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575771 | p.Val142Ser | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575779 | p.Glu144Asp | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575780 | p.Pro145Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575821 | c.474G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575824 | c.477T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575842 | c.495G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575845 | c.498C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575848 | c.501C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575851 | c.504C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575864 | c.517T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575884 | c.537G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575887 | c.540G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575890 | c.543C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575899 | c.552G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| mshA | 575916 | p.Asp190Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| ccsA | 619624 | c.-267C>T | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619634 | c.-257_-255delTCCinsGTG | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619654 | c.-237A>G | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619669 | c.-222G>C | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619672 | c.-219A>C | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 619684 | c.-207G>A | upstream_gene_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620238 | c.348G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620245 | c.355T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620249 | p.Ser120Cys | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620253 | c.363G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620254 | c.364_366delCTCinsTTG | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620263 | p.Gly125Ser | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620271 | c.381C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620388 | c.498A>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620389 | c.499C>T | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620598 | c.708C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620607 | c.717T>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620613 | c.723C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620631 | c.741T>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620649 | c.759A>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620661 | c.771C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620685 | c.795G>A | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| capreomycin | Not assoc w R - Interim | |||||
| amikacin | ||||||
| ccsA | 620698 | p.Val270Ile | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620712 | c.822G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620721 | c.831G>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620733 | c.843G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620739 | c.849A>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620742 | c.852G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620748 | c.858T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620778 | c.888T>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620781 | c.891C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620783 | p.Ala298Val | missense_variant | 0.97 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620787 | c.897C>A | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620796 | c.906C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620829 | c.939G>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620835 | c.945C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| Rv0565c | 657183 | c.288G>A | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657189 | c.282C>A | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657193 | p.Met93Thr | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657196 | p.Asp92Ala | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657200 | p.Thr91Ala | missense_variant | 1.0 | ethionamide | Uncertain significance |
| Rv0565c | 657210 | c.261C>T | synonymous_variant | 1.0 | ethionamide | Not assoc w R - Interim |
| Rv0565c | 657213 | c.258C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657219 | p.Ala84Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657233 | p.Ile80Val | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657240 | p.Glu77Lys | missense_variant | 0.98 | ethionamide | |
| Rv0565c | 657252 | c.219G>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657255 | c.216G>A | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 1.0 | ethionamide | |
| Rv0565c | 657294 | c.177C>A | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657306 | c.165C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657312 | c.159C>T | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657318 | c.153T>C | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657324 | c.147C>G | synonymous_variant | 1.0 | ethionamide | |
| Rv0565c | 657644 | c.-174G>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657659 | c.-189G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657668 | c.-198C>T | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657678 | c.-208A>C | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657695 | c.-225C>G | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657704 | c.-234G>A | upstream_gene_variant | 1.0 | ethionamide | |
| Rv0565c | 657725 | c.-255G>A | upstream_gene_variant | 1.0 | ethionamide | |
| hadA | 731686 | c.-244_-243insATGT | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731689 | c.-240_-237delAGAC | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731695 | c.-235C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731698 | c.-232T>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731708 | c.-222G>A | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731711 | c.-219T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731726 | c.-204C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731729 | c.-201C>T | upstream_gene_variant | 0.96 | isoniazid | |
| hadA | 731753 | c.-177A>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731756 | c.-174C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731774 | c.-156T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731786 | c.-144C>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731789 | c.-141A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731807 | c.-123C>T | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731819 | c.-111G>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731843 | c.-87T>C | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 731852 | c.-78A>G | upstream_gene_variant | 1.0 | isoniazid | |
| hadA | 732305 | p.Ile126Val | missense_variant | 1.0 | isoniazid | |
| hadA | 732308 | p.Val127Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732314 | p.Asn129Asp | missense_variant | 1.0 | isoniazid | |
| hadA | 732319 | c.390G>A | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732321 | p.Glu131Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732329 | p.Leu134Ile | missense_variant | 1.0 | isoniazid | |
| hadA | 732346 | c.417T>C | synonymous_variant | 1.0 | isoniazid | |
| hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 1.0 | isoniazid | |
| hadA | 732396 | p.Gly156Ala | missense_variant | 1.0 | isoniazid | |
| hadA | 732398 | p.Ala157Thr | missense_variant | 1.0 | isoniazid | |
| nusG | 734078 | c.-176C>G | upstream_gene_variant | 0.75 | rifampicin | Uncertain significance |
| nusG | 734093 | c.-161A>G | upstream_gene_variant | 0.9 | rifampicin | |
| nusG | 734111 | c.-143A>G | upstream_gene_variant | 0.92 | rifampicin | |
| nusG | 734114 | c.-140A>G | upstream_gene_variant | 0.92 | rifampicin | |
| nusG | 734120 | c.-134T>C | upstream_gene_variant | 0.92 | rifampicin | Uncertain significance |
| nusG | 734129 | c.-125G>C | upstream_gene_variant | 1.0 | rifampicin | |
| nusG | 734364 | c.111G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734367 | c.114C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734370 | c.117A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734373 | c.120G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734403 | c.150C>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734407 | p.Val52Ile | missense_variant | 1.0 | rifampicin | |
| nusG | 734421 | c.168A>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734424 | c.171G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734439 | c.186C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734451 | c.198G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734454 | c.201A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734472 | c.219T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734475 | c.222T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734478 | c.225C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| nusG | 734499 | c.246G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734520 | c.267C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734532 | c.279A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734541 | c.288A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734559 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734580 | c.327T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734589 | c.336G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734595 | c.342C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734596 | c.343T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734610 | c.357C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734826 | c.573A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734829 | c.576C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| nusG | 734841 | c.588G>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734853 | c.600A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734854 | c.601T>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734870 | p.Ser206Asn | missense_variant | 1.0 | rifampicin | |
| nusG | 734895 | c.642A>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734910 | c.657C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734913 | c.660C>G | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734931 | c.678A>T | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734940 | c.687G>A | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734943 | c.690G>C | synonymous_variant | 1.0 | rifampicin | |
| nusG | 734950 | p.Gly233Thr | missense_variant | 1.0 | rifampicin | |
| mmaA3 | 737834 | p.His106Tyr | missense_variant | 0.93 | isoniazid | |
| mmaA3 | 737841 | c.309A>G | synonymous_variant | 0.93 | isoniazid | |
| mmaA3 | 737844 | c.306G>C | synonymous_variant | 0.93 | isoniazid | |
| mmaA3 | 737856 | c.294C>G | synonymous_variant | 0.86 | isoniazid | |
| mmaA3 | 737877 | p.Arg91Lys | missense_variant | 0.91 | isoniazid | |
| mmaA3 | 737889 | c.261T>C | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 737898 | c.252C>G | synonymous_variant | 0.95 | isoniazid | |
| mmaA3 | 737919 | p.Val77Ile | missense_variant | 1.0 | isoniazid | |
| mmaA3 | 737931 | c.219A>T | synonymous_variant | 1.0 | isoniazid | |
| mmaA3 | 738333 | c.-184C>G | upstream_gene_variant | 1.0 | isoniazid | |
| mmaA3 | 738339 | c.-190G>C | upstream_gene_variant | 1.0 | isoniazid | |
| mmaA3 | 738346 | c.-198_-197delCTinsGC | upstream_gene_variant | 1.0 | isoniazid | |
| mmaA3 | 738348 | c.-199G>C | upstream_gene_variant | 1.0 | isoniazid | |
| rpoB | 760056 | c.250_252delCTCinsTTG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760070 | c.264T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760091 | c.285G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760101 | c.295T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760109 | c.303C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760112 | c.306T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760118 | c.312T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760121 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760130 | p.Asp108Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760139 | c.333A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760142 | c.336C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760145 | c.339C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760181 | c.375T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760196 | c.390C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760244 | c.438G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760274 | c.468G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760295 | c.489C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760307 | c.501T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760310 | c.504G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760328 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760331 | c.525G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760337 | c.531C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760340 | c.534G>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| rpoB | 760358 | c.552C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760361 | c.555T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760370 | c.564C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760376 | p.Asp190Glu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760380 | p.Thr192Leu | missense_variant | 1.0 | rifampicin | |
| rpoB | 760403 | c.597C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760412 | c.606C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760418 | c.612G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760424 | c.618C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760430 | c.624T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760457 | c.651C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760472 | c.666C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760475 | c.669A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760478 | c.672C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760481 | c.675G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760484 | c.678A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760493 | c.687C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760520 | c.714C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760522 | p.Ser239Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760526 | c.720G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760532 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760533 | p.Val243Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 760547 | c.741G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760563 | p.Arg253Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 760591 | p.Val262Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760601 | c.795C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760611 | c.805T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760622 | c.816C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760646 | c.840C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760649 | c.843G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760655 | c.849A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 760661 | c.855A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760667 | c.861G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760670 | c.864G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760674 | c.868T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760679 | c.873A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760683 | c.877T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760724 | c.918T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760730 | c.924T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760748 | c.942C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760757 | c.951T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760759 | p.Val318Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 760769 | c.963C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760793 | c.987A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760805 | c.999G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760817 | c.1011A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760820 | c.1014T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760826 | c.1020C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760830 | c.1024T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760841 | c.1035T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760845 | p.Thr347Pro | missense_variant | 1.0 | rifampicin | |
| rpoB | 760856 | c.1050C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760886 | c.1080A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760892 | c.1086C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760916 | c.1110C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760931 | c.1125C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760937 | c.1131G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 760973 | c.1167G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760982 | c.1176G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760985 | c.1179G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760991 | c.1185G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761006 | c.1200C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761015 | c.1209G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761036 | c.1230G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761037 | c.1231T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761051 | c.1245G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761057 | c.1251G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761060 | c.1254C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761063 | c.1257C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761096 | c.1290G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761097 | c.1291_1293delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761102 | c.1296A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761132 | c.1326G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761133 | c.1327_1329delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761150 | c.1344A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761168 | c.1362C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoB | 761180 | c.1374A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761189 | c.1383T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761192 | c.1386C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761195 | c.1389G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761198 | c.1392G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761240 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761261 | c.1455G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761264 | c.1458C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761345 | c.1539G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761362 | p.Ser519Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761374 | p.Val523Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761423 | c.1617T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761432 | c.1626C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761435 | c.1629T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761438 | c.1632G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761444 | c.1638T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761452 | p.Val549Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761457 | p.Pro551Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761465 | c.1659G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761471 | c.1665C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761477 | c.1671C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761492 | c.1686G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761504 | c.1698C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761510 | c.1704T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761531 | c.1725C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761558 | c.1752C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761666 | c.1860G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761723 | c.1917_1919delAGAinsC | frameshift_variant&missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761735 | c.1929C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761750 | c.1944G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761765 | c.1959T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761772 | p.His656Ala | missense_variant | 1.0 | rifampicin | |
| rpoB | 761778 | p.Asn658Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761791 | p.Arg662His | missense_variant | 1.0 | rifampicin | |
| rpoB | 761813 | c.2007T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761828 | c.2022C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761834 | c.2028T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761837 | c.2031C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761848 | p.Cys681Ser | missense_variant | 1.0 | rifampicin | |
| rpoB | 761852 | c.2046C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761858 | c.2052G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761873 | c.2067A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761885 | c.2079T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761891 | c.2085G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761909 | c.2103T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761912 | c.2106T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761913 | p.Asp703Gln | missense_variant | 1.0 | rifampicin | |
| rpoB | 761916 | p.Asp704Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761921 | c.2115C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761930 | c.2124G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762008 | c.2202C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762014 | c.2208C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoB | 762047 | c.2241G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762053 | c.2247T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762062 | c.2256T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762065 | c.2259T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762083 | c.2277T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762086 | c.2280G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762101 | c.2295C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762114 | p.Ile770Val | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762131 | c.2325C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762134 | c.2328C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762143 | c.2337T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762167 | c.2361T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762185 | c.2379G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762233 | c.2427G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762254 | c.2448T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762257 | c.2451C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762266 | c.2460T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762281 | c.2475G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762284 | c.2478G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762293 | c.2487T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762317 | c.2511A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762338 | c.2532T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762341 | c.2535G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762395 | c.-975G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762398 | c.-972T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762401 | c.-969G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762404 | c.2598T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762410 | c.-960T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762416 | c.2610A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762431 | c.2625C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762449 | c.2643C>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762470 | c.2664G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762491 | c.2685T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762509 | c.-861T>G | upstream_gene_variant | 0.98 | rifampicin | |
| rpoB | 762510 | p.Ala902Pro | missense_variant | 0.98 | rifampicin | Uncertain significance |
| rpoC | 762533 | c.-837T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762536 | c.-834T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762537 | c.-833T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762551 | c.-819C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762563 | c.-807G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762581 | c.-789T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762587 | c.-783G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762776 | c.-594C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762782 | c.2976T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762789 | p.Leu995Met | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 762794 | c.-576C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762795 | p.Asp997Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 762812 | c.3006C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762813 | p.Met1003Val | missense_variant | 1.0 | rifampicin | |
| rpoB | 762818 | c.3012C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762827 | c.3021G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762833 | c.3027C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762857 | c.3051C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762860 | c.3054G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762902 | c.-468C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762917 | c.-453C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762929 | c.3123G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 762962 | c.3156C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 762983 | c.-387C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 762995 | c.3189G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763031 | c.3225T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 763034 | c.-336C>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763040 | c.3234C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763070 | c.3264T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763082 | c.3276C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763085 | c.3279C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763115 | c.3309T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 763127 | c.3321G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763142 | c.-228C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763166 | c.3360A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763169 | c.-201A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763202 | c.-168A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763205 | c.-165G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763226 | c.-144A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoB | 763238 | c.3432T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763241 | c.-129G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763250 | c.-120C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763253 | c.-117G>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763262 | c.-108C>A | upstream_gene_variant | 0.94 | rifampicin | |
| rpoC | 763265 | c.-105G>A | upstream_gene_variant | 0.93 | rifampicin | |
| rpoC | 763402 | c.33C>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763409 | c.40_42delCTTinsTTG | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763414 | c.45T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763441 | c.72C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 763444 | c.75T>C | synonymous_variant | 0.96 | rifampicin | Not assoc w R - Interim |
| rpoC | 763456 | c.87A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763486 | c.117T>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763528 | c.159G>A | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763546 | c.177A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763570 | c.201G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763594 | c.225C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763603 | c.234C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763618 | c.249C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763636 | c.267T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763669 | c.300C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763675 | c.306C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763703 | c.334_336delTCGinsAGC | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763709 | c.340C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 763714 | c.345G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 763726 | c.357C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763732 | c.363C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763741 | c.372C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763744 | c.375G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763765 | c.396T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 763771 | c.402C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763780 | c.411C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763792 | p.Glu141Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763801 | c.432C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763807 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 763836 | p.Ala156Val | missense_variant | 1.0 | rifampicin | |
| rpoC | 763851 | p.Ala161Gly | missense_variant | 1.0 | rifampicin | |
| rpoC | 763855 | c.486C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763858 | c.489A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763872 | p.Gly168Ala | missense_variant | 1.0 | rifampicin | |
| rpoC | 763876 | p.Glu169Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 763879 | c.510A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763888 | c.519G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763891 | c.522G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763894 | c.525A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763936 | c.567C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763939 | c.570G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763951 | c.582G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763963 | c.594C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763967 | p.Gly200Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 763972 | c.603C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763987 | c.618C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763996 | c.627T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764005 | c.636G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764040 | p.Ser224Thr | missense_variant | 1.0 | rifampicin | |
| rpoC | 764044 | c.675T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764059 | c.690G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764140 | c.771C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764159 | c.790C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764167 | c.798G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764188 | c.819A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764195 | p.Ser276Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 764215 | c.846A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764218 | c.849C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764242 | c.873C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764245 | c.876C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764246 | c.877_879delCTCinsTTG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764263 | c.894G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764266 | c.897T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764278 | c.909A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764293 | c.924G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764317 | c.948C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764320 | c.951C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764377 | c.1008C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764405 | c.1036_1038delAGGinsCGC | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764428 | c.1059G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764536 | c.1167G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764554 | c.1185C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764575 | c.1206T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764578 | c.1209C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764593 | c.1224C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764605 | c.1236G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764626 | c.1257C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764668 | c.1299C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764686 | c.1317C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764782 | c.1413C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764797 | c.1428G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764803 | c.1434C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 764858 | c.1489T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764887 | c.1518G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoC | 764888 | c.1519_1521delTTGinsCTC | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 764896 | c.1527C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764902 | c.1533C>T | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764911 | c.1542A>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 764923 | c.1554A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 764932 | c.1563C>G | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764948 | c.1579T>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 764968 | c.1599T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765007 | c.1638T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765008 | c.1639T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765013 | c.1644C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765019 | c.1650A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765040 | c.1671T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765082 | c.1713G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765089 | c.1720T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765208 | c.1839T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765223 | c.1854G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765233 | p.Ala622Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 765247 | c.1878C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765248 | c.1879T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765251 | c.1882_1884delAGCinsTCG | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765278 | c.1909C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765283 | c.1914C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765292 | c.1923G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765300 | p.Val644Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765316 | c.1947G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765319 | c.1950A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765328 | p.His653Gln | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765330 | p.Ser654Asn | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765334 | c.1965C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765343 | c.1974G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765352 | c.1983G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765367 | c.1998C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765370 | c.2001G>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765383 | p.Met672Leu | missense_variant | 0.98 | rifampicin | Uncertain significance |
| rpoC | 765406 | c.2037G>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765409 | c.2040T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765412 | c.2043T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765421 | c.2052C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765452 | p.Ala695Ser | missense_variant | 0.98 | rifampicin | |
| rpoC | 765466 | c.2097C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765478 | c.2109T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765493 | c.2124G>C | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765499 | c.2130C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765508 | c.2139C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765517 | c.2148C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 765529 | c.2160C>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765541 | c.2172C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 765553 | c.2184C>T | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 765556 | c.2187G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765562 | c.2193G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765578 | c.2209C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 765622 | p.Glu751Asp | missense_variant | 1.0 | rifampicin | |
| rpoC | 765625 | c.2256C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765658 | c.2289C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765700 | c.2331T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765728 | p.Gln787Lys | missense_variant | 1.0 | rifampicin | |
| rpoC | 765734 | c.2365T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765739 | c.2370G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765752 | p.Asp795Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 765772 | c.2403C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765784 | c.2415C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765790 | c.2421C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765793 | c.2424C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765796 | c.2427C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765811 | c.2442T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765814 | c.2445A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765826 | c.2457T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765835 | c.2466C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765883 | c.2514C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765886 | c.2517C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765892 | c.2523T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766012 | c.2643C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766021 | c.2652G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766061 | p.Val898Ile | missense_variant | 1.0 | rifampicin | |
| rpoC | 766082 | p.Ala905Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766093 | c.2724C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766095 | p.Thr909Ser | missense_variant | 1.0 | rifampicin | |
| rpoC | 766105 | c.2736C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766123 | c.2754C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766129 | c.2760C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766288 | c.2919C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766309 | c.2940G>A | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 766315 | c.2946C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766321 | c.2952C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766348 | c.2979A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766369 | c.3000C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766381 | c.3012C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766384 | c.3015A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766393 | c.3024C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766402 | c.3033C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766408 | c.3039C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766426 | c.3057C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766456 | c.3087C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766486 | c.3117A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766492 | c.3123T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766522 | c.3153C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766528 | c.3159T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766530 | p.Arg1054Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 766549 | c.3180G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766573 | c.3204T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766585 | c.3216T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766594 | c.3225G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766607 | p.Ile1080Leu | missense_variant | 0.98 | rifampicin | |
| rpoC | 766630 | c.3261G>T | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766660 | c.3291G>A | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766666 | c.3297C>G | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766700 | c.3331C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766733 | c.3364C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766738 | c.3369G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766741 | c.3372G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766747 | c.3378C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766750 | c.3381C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 766798 | c.3429C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 766801 | c.3432C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 766843 | c.3474T>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766876 | c.3507C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766883 | p.Ser1172Ala | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 766894 | c.3525T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766895 | c.3526T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766900 | c.3531T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766903 | c.3534C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766918 | c.3549C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766930 | c.3561G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766933 | c.3564A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766945 | c.3576A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766963 | c.3594T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766996 | c.3627C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767002 | c.3633G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767014 | c.3645G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767033 | c.3664_3666delTCGinsAGT | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767059 | c.3690T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767062 | c.3693C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767098 | c.3729T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767119 | c.3750A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767134 | c.3765C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767158 | c.3789T>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 767167 | c.3798C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 767180 | p.Ala1271Gln | missense_variant | 1.0 | rifampicin | |
| rpoC | 767191 | c.3822C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767206 | c.3837C>G | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767209 | c.3840T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767221 | c.3852C>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoC | 767230 | c.3861G>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767233 | c.3864T>C | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoC | 767263 | c.3894T>G | synonymous_variant | 0.95 | rifampicin | |
| rpoC | 767264 | p.Ala1299Gln | missense_variant | 0.95 | rifampicin | |
| rpoC | 767278 | c.3909T>C | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 767281 | c.3912C>G | synonymous_variant | 0.94 | rifampicin | Not assoc w R - Interim |
| rpoC | 767284 | c.3915C>T | synonymous_variant | 0.94 | rifampicin | |
| mmpL5 | 775864 | p.Ala873Ser | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775865 | c.2616T>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775874 | c.2607C>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775883 | p.Ile866Leu | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775886 | c.2595A>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775889 | c.2592C>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775909 | p.Leu858Phe | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775910 | c.2571G>A | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775916 | c.2565T>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775921 | c.2560C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775937 | c.2544G>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775943 | c.2538C>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775946 | c.2535C>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775951 | c.2530C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775961 | c.2520C>G | synonymous_variant | 0.96 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.93 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775975 | c.2506T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775981 | p.Leu834Met | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 775997 | c.2484T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776000 | p.Leu827Ile | missense_variant | 0.79 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776009 | c.2472A>G | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776030 | c.2451G>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776036 | c.2445G>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776039 | c.2442C>G | synonymous_variant | 0.62 | bedaquiline | |
| clofazimine | ||||||
| mmpL5 | 776056 | p.Val809Leu | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| rpsL | 781571 | c.12C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781595 | c.36T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781598 | c.39G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781605 | p.Ile16Val | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781608 | p.Ser17Ala | missense_variant | 1.0 | streptomycin | |
| rpsL | 781616 | c.57C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781628 | c.69T>C | synonymous_variant | 0.97 | streptomycin | Not assoc w R - Interim |
| rpsL | 781655 | c.96T>C | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781658 | c.99A>G | synonymous_variant | 0.97 | streptomycin | |
| rpsL | 781682 | c.123T>C | synonymous_variant | 0.98 | streptomycin | |
| rpsL | 781715 | c.156T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781718 | c.159C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781721 | c.162C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781728 | c.169T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781751 | c.192G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781754 | c.195G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781760 | c.201T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781766 | c.207C>T | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781772 | c.213C>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781793 | c.234G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781808 | c.249C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781832 | c.273T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781835 | c.276T>C | synonymous_variant | 1.0 | streptomycin | Not assoc w R - Interim |
| rpsL | 781859 | c.300T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781865 | c.306G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781883 | c.324G>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781886 | c.327C>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| rpsL | 781933 | c.374G>A | splice_region_variant&stop_retained_variant | 1.0 | streptomycin | |
| rplC | 800516 | c.-293G>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800540 | c.-269T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800546 | c.-263T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800567 | c.-242A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800579 | c.-230C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800582 | c.-227C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800612 | c.-197A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800618 | c.-191T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800621 | c.-188G>A | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800627 | c.-182C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800648 | c.-161A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800654 | c.-155T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800693 | c.-116A>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800703 | c.-106T>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800714 | c.-95C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800715 | c.-94A>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800723 | c.-86C>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800744 | c.-65G>C | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800745 | c.-64_-62delCTCinsTTG | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800759 | c.-50C>T | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800762 | c.-47T>G | upstream_gene_variant | 1.0 | linezolid | |
| rplC | 800814 | c.6A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800815 | c.7C>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800820 | c.12G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800829 | c.21C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800844 | c.36T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800856 | c.48A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800865 | c.57A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800867 | p.Ser20Asn | missense_variant | 1.0 | linezolid | |
| rplC | 800872 | c.64_66delAGAinsCGG | synonymous_variant | 1.0 | linezolid | |
| rplC | 800877 | c.69A>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800880 | c.72A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800901 | c.93C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800910 | c.102C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 800913 | c.105G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 800916 | c.108A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800919 | c.111C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 800931 | c.123G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 800934 | c.126C>G | synonymous_variant | 0.92 | linezolid | |
| rplC | 800937 | c.129A>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801279 | c.471G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801285 | c.477G>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801309 | c.501C>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801312 | c.504G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801324 | c.516T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801330 | c.522G>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801333 | c.525G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801339 | c.531T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801341 | p.Leu178Gln | missense_variant | 1.0 | linezolid | |
| rplC | 801348 | c.540T>G | synonymous_variant | 1.0 | linezolid | |
| rplC | 801349 | p.Leu181Val | missense_variant | 1.0 | linezolid | |
| rplC | 801357 | c.549T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801372 | c.564G>A | synonymous_variant | 0.95 | linezolid | |
| rplC | 801385 | c.577C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801402 | c.594T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801405 | c.597T>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801408 | c.600C>A | synonymous_variant | 1.0 | linezolid | |
| rplC | 801423 | c.615G>C | synonymous_variant | 1.0 | linezolid | |
| rplC | 801426 | c.618C>T | synonymous_variant | 1.0 | linezolid | |
| rplC | 801427 | p.Met207Val | missense_variant | 1.0 | linezolid | |
| rplC | 801437 | p.Ser210Thr | missense_variant | 1.0 | linezolid | |
| fbiC | 1303441 | c.511T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303449 | c.519C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303462 | p.Ala178Ser | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303470 | c.540T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303480 | p.Gln184Glu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303488 | c.558G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303506 | c.576C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303512 | c.582T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303534 | p.Ser202Ala | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303538 | p.Arg203Leu | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303545 | c.615A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303575 | c.645G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303578 | c.648G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303584 | c.654C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303596 | c.666G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303605 | c.675C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303608 | c.678G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303614 | c.684C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303617 | c.687C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303620 | c.690C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1303629 | c.699C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303632 | c.702T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303659 | c.729T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303661 | p.Val244Ala | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303674 | c.744C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303686 | c.756C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303704 | c.774T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303708 | c.778T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303729 | c.799_801delCTAinsTTG | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1303737 | c.807G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304496 | c.1566T>A | synonymous_variant | 0.92 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304499 | c.1569T>G | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304502 | c.1572G>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304526 | c.1596T>G | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304532 | c.1602G>C | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304533 | c.1603T>C | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304541 | c.1611C>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304544 | c.1614T>C | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304546 | p.Val539Ala | missense_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304565 | c.1635C>G | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304568 | c.1638T>C | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304574 | c.1644C>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304580 | c.1650T>C | synonymous_variant | 0.97 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304610 | c.1680C>G | synonymous_variant | 0.96 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304613 | c.1683T>A | synonymous_variant | 0.96 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304625 | c.1695C>T | synonymous_variant | 0.97 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304634 | c.1704C>G | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304640 | c.1710A>C | synonymous_variant | 0.94 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304646 | c.1716T>C | synonymous_variant | 0.93 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304658 | c.1728C>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304670 | c.1740G>C | synonymous_variant | 0.9 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304811 | c.1881C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304817 | c.1887T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304823 | c.1893C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304832 | c.1902C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304853 | c.1923C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304856 | c.1926C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304868 | c.1938G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304871 | c.1941G>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304872 | c.1942_1943delAGinsTC | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304875 | p.Ile649Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304883 | c.1953G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304893 | p.Gly655Ser | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304915 | p.Asp662Gly | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304925 | c.1995G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1304928 | c.1998T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304934 | c.2004C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304937 | c.2007G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304946 | c.2016G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304955 | c.2025G>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304958 | c.2028T>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304991 | c.2061G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304994 | c.2064A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1304995 | p.Leu689Met | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305006 | c.2076A>G | synonymous_variant | 0.95 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305012 | c.2082G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305015 | c.2085G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305021 | c.2091C>A | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305033 | c.2103T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305357 | c.2427C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | Not assoc w R - Interim | |||||
| clofazimine | Not assoc w R - Interim | |||||
| fbiC | 1305361 | c.2431C>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305393 | c.2463T>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305397 | p.Glu823Gln | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiC | 1305405 | c.2475A>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| sigE | 1364703 | c.291G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364712 | c.300T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364721 | c.309C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364726 | p.Asn105Ser | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364733 | p.His107Gln | missense_variant | 1.0 | pyrazinamide | |
| sigE | 1364736 | c.324T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364742 | c.330A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364745 | c.333C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364746 | c.334C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364751 | c.339C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364760 | c.348C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364763 | c.351T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364767 | c.355A>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364790 | c.378T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364799 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364802 | c.390C>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364811 | c.399A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364820 | c.408A>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364839 | c.427T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364847 | c.435G>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364856 | c.444C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364868 | c.456T>C | synonymous_variant | 0.97 | pyrazinamide | |
| sigE | 1364871 | c.459C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364883 | c.471G>A | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364889 | c.477A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| sigE | 1364892 | c.480C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364913 | c.501C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364919 | c.507T>C | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364925 | c.513C>G | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364928 | c.516C>T | synonymous_variant | 1.0 | pyrazinamide | |
| sigE | 1364952 | c.540A>C | synonymous_variant | 1.0 | pyrazinamide | |
| embR | 1416289 | c.1059G>A | synonymous_variant | 1.0 | ethambutol | |
| embR | 1416301 | c.1047C>A | synonymous_variant | 1.0 | ethambutol | |
| embR | 1416310 | c.1038G>C | synonymous_variant | 1.0 | ethambutol | |
| embR | 1416313 | c.1035A>G | synonymous_variant | 1.0 | ethambutol | |
| embR | 1416316 | c.1032C>G | synonymous_variant | 1.0 | ethambutol | |
| embR | 1416330 | p.Val340Ile | missense_variant | 1.0 | ethambutol | |
| embR | 1416332 | p.Tyr339Phe | missense_variant | 1.0 | ethambutol | |
| embR | 1416335 | p.Asn338Ser | missense_variant | 1.0 | ethambutol | |
| embR | 1416343 | c.1005G>C | synonymous_variant | 1.0 | ethambutol | |
| embR | 1416364 | c.984C>T | synonymous_variant | 1.0 | ethambutol | |
| atpE | 1460807 | c.-238C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460816 | c.-229T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460828 | c.-217C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460831 | c.-214T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460840 | c.-205A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460855 | c.-190T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460858 | c.-187C>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460882 | c.-163T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460894 | c.-151A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460895 | c.-150_-148delGCAinsTCC | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460900 | c.-145T>C | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460904 | c.-141C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| atpE | 1460918 | c.-127A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471925 | n.80T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1471932 | n.87A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472030 | n.185G>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472031 | n.186G>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472033 | n.188A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472040 | n.195T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472445 | n.601_604delTCTC | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472451 | n.606_607insCGGG | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472460 | n.615T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472461 | n.616G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472463 | n.618G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472464 | n.619A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472489 | n.644A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472686 | n.841G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472847 | n.1002G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472848 | n.1003T>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472849 | n.1004C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472857 | n.1012A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472858 | n.1013G>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472859 | n.1014G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1472860 | n.1015C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| streptomycin | ||||||
| amikacin | ||||||
| rrs | 1473288 | n.1443C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrs | 1473291 | n.1446G>T | non_coding_transcript_exon_variant | 1.0 | kanamycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| streptomycin | ||||||
| amikacin | Uncertain significance | |||||
| rrl | 1473417 | n.-241C>T | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473420 | n.-238A>G | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473421 | n.-237G>A | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473437 | n.-221T>C | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473449 | n.-209G>A | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473454 | n.-204A>G | upstream_gene_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473676 | n.19G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473797 | n.140G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473831 | n.174G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473887 | n.230T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473888 | n.231T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1473899 | n.242A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473918 | n.261C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473924 | n.267_268insT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473943 | n.286G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473945 | n.288T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473946 | n.289A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1473981 | n.324delGinsAT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473994 | n.337C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Not assoc w R | |||||
| rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474011 | n.354G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474018 | n.361G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474030 | n.373G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474061 | n.404T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474089 | n.432C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474093 | n.436G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474100 | n.443C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474103 | n.446A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474110 | n.453A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474111 | n.454T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474130 | n.473C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474140 | n.483C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474151 | n.494C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474181 | n.524C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474291 | n.635_649delTTCCTCTCCGGAGGA | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474447 | n.790G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474627 | n.970G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474717 | n.1060A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474783 | n.1126G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1474991 | n.1334T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1474995 | n.1338T>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475005 | n.1348C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475006 | n.1349A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475007 | n.1350C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475013 | n.1356G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475018 | n.1361G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475027 | n.1370G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475028 | n.1371G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475061 | n.1404C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475369 | n.1712G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475401 | n.1745delC | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475404 | n.1747A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475405 | n.1748A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475429 | n.1772G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475453 | n.1796T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475480 | n.1823A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475487 | n.1830C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | Uncertain significance | |||||
| rrl | 1475604 | n.1947A>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475605 | n.1948A>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475617 | n.1960C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475625 | n.1968G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475637 | n.1980T>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475657 | n.2000A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1475760 | n.2103C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1475954 | n.2297A>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1475999 | n.2342G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476030 | n.2373A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476032 | n.2375C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476033 | n.2376T>C | non_coding_transcript_exon_variant | 0.93 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476034 | n.2377C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476045 | n.2388G>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476047 | n.2390G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476077 | n.2420T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476095 | n.2438C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476214 | n.2557G>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476215 | n.2558C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.97 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Not assoc w R |
| linezolid | Uncertain significance | |||||
| rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.99 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476689 | n.3032A>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1476690 | n.3033C>T | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.98 | capreomycin | |
| linezolid | ||||||
| rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.98 | capreomycin | Uncertain significance |
| linezolid | ||||||
| rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.97 | capreomycin | |
| linezolid | ||||||
| rrl | 1476725 | n.3068C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
| linezolid | Uncertain significance | |||||
| rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476732 | n.3075T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476750 | n.3093T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476755 | n.3098G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476759 | n.3102T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476770 | n.3113T>C | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| rrl | 1476771 | n.3114G>A | non_coding_transcript_exon_variant | 1.0 | capreomycin | |
| linezolid | ||||||
| inhA | 1673475 | c.-727A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673499 | c.-703T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1673505 | c.-697A>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673517 | c.-685G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673524 | c.-678C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673535 | c.-667A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673565 | c.-637G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673580 | c.-622T>C | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | ||||||
| inhA | 1673589 | c.-613A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673595 | c.-607A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673596 | c.-606A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673604 | c.-598G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673607 | c.-595T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673829 | c.-373C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673830 | c.-372_-371delAAinsCG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673838 | c.-364T>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673841 | c.-361A>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673844 | c.-358G>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673847 | c.-355A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673853 | c.-349A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673856 | c.-346T>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673865 | c.-337C>G | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673870 | c.-332_-331delGCinsTG | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673877 | c.-325C>T | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1673901 | c.-301A>C | upstream_gene_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674480 | c.279T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674489 | c.288G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674507 | c.306G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674534 | c.333G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| inhA | 1674537 | c.336C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674540 | c.339C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674555 | c.354G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674561 | c.360C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674588 | c.387G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674601 | p.Leu134Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674618 | c.417C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674619 | p.Pro140Ser | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674624 | c.423A>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674655 | c.454_456delAGCinsTCG | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674669 | c.468G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674687 | c.486G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674696 | c.495G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674729 | c.528G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674745 | p.Tyr182Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674759 | c.558G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674765 | c.564C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674774 | c.573A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674777 | c.576C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674792 | c.591G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674820 | c.619_621delCTCinsTTG | synonymous_variant | 0.96 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674828 | c.627G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674846 | p.Ile215Met | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674876 | c.675C>G | synonymous_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674879 | c.678T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674888 | c.687C>T | synonymous_variant | 0.95 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674904 | p.Ala235Pro | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674909 | c.708G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674915 | c.714C>G | synonymous_variant | 0.97 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674939 | c.738G>A | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | Not assoc w R - Interim | |||||
| inhA | 1674942 | c.741T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674960 | c.759C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674966 | c.765T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674967 | p.Asp256Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| rpsA | 1833256 | c.-286C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833262 | c.-280T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833273 | c.-269G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833277 | c.-265C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833283 | c.-259C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833288 | c.-254_-253delTGinsCC | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833304 | c.-238C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833310 | c.-232T>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833319 | c.-223C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| rpsA | 1833517 | c.-24delC | upstream_gene_variant | 0.92 | pyrazinamide | |
| rpsA | 1833532 | c.-10A>C | upstream_gene_variant | 0.96 | pyrazinamide | |
| rpsA | 1833568 | c.27G>C | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833589 | c.48A>T | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1833595 | c.54T>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1833613 | c.72C>A | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833619 | c.78A>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833661 | c.120A>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833667 | c.126C>G | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1833703 | c.162C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833724 | c.183C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833727 | c.186G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833745 | c.204G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833760 | c.219C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833790 | c.249T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833793 | c.252C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833802 | c.261A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833808 | c.267G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833811 | c.270G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833832 | c.291G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833859 | c.318C>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1833895 | c.354G>C | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1833934 | c.393C>T | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833970 | c.429G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833994 | c.453G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834105 | c.564C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834114 | c.573G>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834150 | c.609G>C | synonymous_variant | 0.9 | pyrazinamide | |
| rpsA | 1834153 | c.612T>C | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1834154 | p.Asn205Gln | missense_variant | 0.88 | pyrazinamide | |
| rpsA | 1834157 | c.616T>C | synonymous_variant | 0.88 | pyrazinamide | |
| rpsA | 1834162 | c.621A>G | synonymous_variant | 0.89 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834165 | c.624A>G | synonymous_variant | 0.9 | pyrazinamide | |
| rpsA | 1834177 | c.636A>C | synonymous_variant | 0.93 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834186 | c.645C>G | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834189 | c.648G>T | synonymous_variant | 0.94 | pyrazinamide | |
| rpsA | 1834195 | c.654G>C | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834231 | c.690T>G | synonymous_variant | 0.97 | pyrazinamide | |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834261 | c.720A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834264 | c.723G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834297 | c.756C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834303 | c.762T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834306 | c.765T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834318 | c.777C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834336 | c.795C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834348 | c.807T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834375 | c.834G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834396 | c.855G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834411 | c.870T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834423 | c.882G>T | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834451 | c.910T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834456 | c.915T>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834465 | c.924T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834468 | c.927A>G | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.98 | pyrazinamide | |
| rpsA | 1834519 | c.978G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834603 | c.1062G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834609 | c.1068T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834612 | c.1071G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834633 | c.1092A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834639 | c.1098T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834654 | c.1113G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834699 | p.Glu386Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 0.92 | pyrazinamide | |
| tsnR | 1853369 | c.-237C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCG | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853375 | c.-231G>A | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853384 | c.-222G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853393 | c.-213C>T | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| ndh | 2101777 | c.1266C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | ||||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2101783 | c.1260T>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101795 | c.1248G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101804 | c.1239T>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101813 | c.1230G>A | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101825 | c.1218G>A | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101837 | p.Ala402Val | missense_variant | 1.0 | isoniazid | Uncertain significance |
| delamanid | ||||||
| ethionamide | Uncertain significance | |||||
| ndh | 2101858 | p.Ile395Met | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101873 | c.1170T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2101879 | c.1164C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | ||||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2101890 | p.Val385Leu | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102617 | c.426C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102632 | c.411C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2102638 | c.405A>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102644 | c.399A>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102671 | c.372T>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102674 | c.369G>A | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102677 | c.366C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102683 | c.360T>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102686 | c.357G>C | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102700 | c.343C>T | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102711 | p.Pro111Asp | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102718 | p.Gln109Glu | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102723 | p.Thr107Ser | missense_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102895 | c.148C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| delamanid | Not assoc w R - Interim | |||||
| ethionamide | Not assoc w R - Interim | |||||
| ndh | 2102902 | c.141C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| ndh | 2102908 | c.135C>G | synonymous_variant | 1.0 | isoniazid | |
| delamanid | ||||||
| ethionamide | ||||||
| katG | 2155017 | c.1095G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155026 | c.1086C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155047 | c.1065C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155054 | p.Tyr353Phe | missense_variant | 1.0 | isoniazid | |
| katG | 2155056 | c.1056A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155062 | c.1050T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155068 | c.1044T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155071 | c.1041T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155080 | c.1032G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155083 | c.1029G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155086 | c.1026G>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155119 | c.993T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155131 | c.981A>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| katG | 2155134 | c.978G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155144 | p.Asn323Pro | missense_variant | 1.0 | isoniazid | |
| katG | 2155152 | c.960A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155155 | c.957C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155185 | c.927T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155188 | p.Thr308Lys | missense_variant | 1.0 | isoniazid | |
| katG | 2155191 | c.921A>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155203 | c.909G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155581 | c.531C>A | synonymous_variant | 0.91 | isoniazid | |
| katG | 2155587 | c.525G>C | synonymous_variant | 0.91 | isoniazid | |
| katG | 2155590 | c.522A>G | synonymous_variant | 0.91 | isoniazid | |
| katG | 2155614 | c.498T>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155617 | p.Ile165Leu | missense_variant | 1.0 | isoniazid | |
| katG | 2155626 | c.486G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155632 | c.480A>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155637 | p.Leu159Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155641 | p.Lys157Asn | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155656 | c.456G>A | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155661 | p.Val151Ile | missense_variant | 1.0 | isoniazid | |
| katG | 2155680 | c.432G>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155691 | c.421T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155695 | c.417C>G | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155716 | c.396T>C | synonymous_variant | 1.0 | isoniazid | |
| katG | 2155728 | c.384G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517950 | c.-165C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517962 | c.-153C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517965 | c.-150C>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517974 | c.-141T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517983 | c.-132T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517993 | c.-122G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518019 | c.-96A>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518025 | c.-90G>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518031 | c.-84G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518034 | c.-81T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518040 | c.-75G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518041 | c.-74T>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518049 | c.-66G>C | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518053 | c.-62_-60delATTinsCTG | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518073 | c.-42T>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518146 | p.Phe11Tyr | missense_variant | 1.0 | isoniazid | |
| kasA | 2518152 | p.Ser13Asn | missense_variant | 1.0 | isoniazid | |
| kasA | 2518162 | c.48G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518169 | p.Val19Leu | missense_variant | 1.0 | isoniazid | |
| kasA | 2518172 | p.Thr20Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518190 | p.Ser26Ala | missense_variant | 1.0 | isoniazid | |
| kasA | 2518199 | p.Ile29Val | missense_variant | 0.97 | isoniazid | |
| kasA | 2518219 | c.105T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518220 | c.106C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518245 | p.His44Arg | missense_variant | 1.0 | isoniazid | |
| kasA | 2518248 | p.Ala45Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518261 | p.Glu49Asp | missense_variant | 1.0 | isoniazid | |
| kasA | 2518273 | c.159G>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518475 | c.361A>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518480 | c.366T>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518492 | c.378C>T | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518504 | c.390T>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518506 | p.Ala131Glu | missense_variant | 0.93 | isoniazid | |
| kasA | 2518519 | c.405G>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518528 | c.414C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518531 | c.417G>A | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518534 | c.420G>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518561 | c.447T>C | synonymous_variant | 0.93 | isoniazid | |
| kasA | 2518606 | c.492G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518609 | p.Met165Ile | missense_variant | 1.0 | isoniazid | |
| kasA | 2518651 | c.537C>G | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518657 | c.543G>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518663 | c.549T>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518672 | c.558G>C | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518678 | c.564C>T | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518681 | c.567C>T | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518684 | c.570C>G | synonymous_variant | 0.92 | isoniazid | |
| kasA | 2518687 | p.Asp191Glu | missense_variant | 0.94 | isoniazid | |
| kasA | 2518693 | c.579C>G | synonymous_variant | 0.94 | isoniazid | |
| kasA | 2518702 | c.588C>T | synonymous_variant | 0.91 | isoniazid | |
| kasA | 2518711 | c.597A>G | synonymous_variant | 0.9 | isoniazid | |
| kasA | 2518714 | c.600A>C | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518717 | c.603C>G | synonymous_variant | 0.96 | isoniazid | |
| kasA | 2518723 | c.609G>A | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518735 | c.621C>T | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518747 | c.633C>G | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518768 | c.654C>G | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2518783 | c.669T>C | synonymous_variant | 0.98 | isoniazid | |
| kasA | 2518789 | c.675G>C | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518795 | c.681C>A | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518798 | c.684G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518825 | c.711T>C | synonymous_variant | 0.97 | isoniazid | |
| kasA | 2518840 | c.726C>G | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518843 | c.729T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518846 | c.732G>C | synonymous_variant | 0.95 | isoniazid | |
| kasA | 2518855 | c.741C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518864 | c.750G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519146 | c.1032C>A | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519152 | c.1038G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519167 | c.1053T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519194 | c.1080G>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519195 | p.Thr361Ser | missense_variant | 1.0 | isoniazid | |
| kasA | 2519203 | c.1089C>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519206 | c.1092C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519209 | c.1095C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519215 | c.1101C>T | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519227 | c.1113G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2519236 | c.1122G>A | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726645 | c.453C>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726654 | c.462G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ahpC | 2726657 | c.465A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726660 | c.468C>T | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726669 | c.477T>C | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726675 | c.483A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726681 | c.489A>G | synonymous_variant | 1.0 | isoniazid | |
| ahpC | 2726687 | c.495C>G | synonymous_variant | 1.0 | isoniazid | |
| folC | 2747047 | c.552C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747053 | c.546C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747062 | c.537A>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747086 | c.513A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747089 | c.510G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747092 | p.Asp169Glu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747098 | c.501C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747107 | c.492G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747110 | c.489T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| folC | 2747113 | c.486C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| Rv2477c | 2783314 | c.729C>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783320 | c.723C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783332 | c.711T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783347 | c.696C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783350 | c.693T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783353 | c.690T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783362 | c.681G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783371 | c.672A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783374 | c.669G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783410 | c.633G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783419 | c.624G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783427 | p.Pro206Ala | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Uncertain significance | |||||
| ethambutol | Uncertain significance | |||||
| amikacin | ||||||
| Rv2477c | 2783431 | c.612C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783437 | c.606G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783458 | c.585G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783461 | c.582T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783464 | c.579A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783467 | c.576G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783473 | c.570A>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783502 | c.541T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783512 | c.531A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783527 | c.516A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783535 | c.508C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783542 | c.501G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783548 | c.495T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783563 | c.480A>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783572 | c.471A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783578 | c.465G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783602 | c.441G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783605 | c.438T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783623 | c.420G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783632 | c.411C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783656 | c.387G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783665 | c.378A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783683 | c.360A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783691 | c.352C>T | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783718 | c.325T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783719 | c.324A>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783743 | c.300C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783751 | p.Ile98Val | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783761 | c.282G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783766 | p.Met93Leu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783788 | c.255T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783794 | c.249G>A | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783797 | p.Asp82Glu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783806 | c.237G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783821 | p.Gln74Leu | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783827 | c.216C>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783833 | c.210G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783836 | c.207C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783846 | p.Thr66Asn | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783857 | c.186C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783860 | c.183T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783881 | c.160_162delTTGinsCTC | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783884 | c.159T>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783920 | c.123G>T | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2783938 | c.105T>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783956 | p.Tyr29Phe | missense_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783962 | c.81T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | ||||||
| moxifloxacin | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | Not assoc w R - Interim | |||||
| Rv2477c | 2783968 | c.75G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783971 | c.72G>C | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783980 | c.63C>G | synonymous_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| Rv2477c | 2783992 | c.51T>C | synonymous_variant | 1.0 | kanamycin | Not assoc w R - Interim |
| levofloxacin | Not assoc w R - Interim | |||||
| moxifloxacin | ||||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| amikacin | ||||||
| Rv2477c | 2784051 | c.-9C>A | upstream_gene_variant | 1.0 | kanamycin | |
| levofloxacin | ||||||
| moxifloxacin | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| amikacin | ||||||
| pepQ | 2859723 | c.696T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | Not assoc w R - Interim | |||||
| pepQ | 2859732 | c.687C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859735 | c.684G>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859765 | c.654G>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859771 | c.648T>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859774 | c.645C>T | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859778 | p.Val214Asp | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859780 | p.Gln213Ala | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859783 | c.636G>C | synonymous_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2859791 | p.Ala210Ser | missense_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860422 | c.-4G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860424 | c.-6A>T | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860425 | c.-7A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860446 | c.-28T>A | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860456 | c.-38G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860467 | c.-49G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860472 | c.-54G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860475 | c.-57C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860487 | c.-69G>A | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860490 | c.-72G>C | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860493 | c.-75C>T | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| pepQ | 2860502 | c.-84A>G | upstream_gene_variant | 1.0 | bedaquiline | |
| clofazimine | ||||||
| Rv2681 | 2996987 | c.249A>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997011 | c.273C>T | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997013 | p.Gly92Val | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997021 | c.283T>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997028 | p.Val97Ala | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997033 | p.Ala99Arg | missense_variant | 1.0 | capreomycin | |
| Rv2681 | 2997038 | c.300G>C | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997053 | c.315C>G | synonymous_variant | 1.0 | capreomycin | |
| Rv2681 | 2997054 | p.Ser106Gly | missense_variant | 1.0 | capreomycin | Uncertain significance |
| Rv2681 | 2997060 | p.Asn108Asp | missense_variant | 1.0 | capreomycin | |
| Rv2752c | 3064790 | c.1402T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064803 | c.1389C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064815 | c.1377T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064832 | p.Ala454Thr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064835 | p.Ile453Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064838 | c.1354T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064839 | c.1353C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064860 | c.1332G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064989 | c.1203G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3064998 | c.1194A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065040 | c.1150_1152delCTCinsTTG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065049 | c.1143G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065055 | c.1137T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065061 | c.1131C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065070 | c.1122C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065073 | c.1119C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065085 | c.1105_1107delAGGinsCGC | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065088 | c.1104A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065097 | c.1095C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065106 | c.1086C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065109 | c.1081_1083delAGAinsCGG | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065130 | c.1062A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065133 | c.1059T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065142 | c.1050A>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065146 | p.Phe349Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065154 | c.1038G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065186 | c.1006T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065190 | p.Ile334Val | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065199 | c.993T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065202 | c.990T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065205 | c.987T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065210 | c.982T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065223 | c.969T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065229 | c.963G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065232 | c.960T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065235 | c.957G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065241 | c.951A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065625 | c.567G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065901 | c.291A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065916 | c.276T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065919 | c.273G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065922 | c.270T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065946 | p.Gly82Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065949 | c.243C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3065957 | c.235T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3065963 | c.229C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| Rv2752c | 3066420 | c.-229C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066423 | c.-232C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066426 | c.-235T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066429 | c.-238G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066432 | c.-241T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066437 | c.-246G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066459 | c.-268T>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066465 | c.-276_-274delGGGinsAGC | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066471 | c.-280A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066474 | c.-283G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066477 | c.-286C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066480 | c.-291_-289delGCCinsTCT | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066483 | c.-292T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066501 | c.-310G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066527 | c.-336C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066549 | c.-358T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066560 | c.-369C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066567 | c.-376C>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066573 | c.-382G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066579 | c.-388A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066583 | c.-392C>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066597 | c.-406C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066603 | c.-412A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066612 | c.-421G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066617 | c.-426G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066618 | c.-427A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066633 | c.-442T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066644 | c.-453T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066647 | c.-456G>A | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066654 | c.-463G>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066676 | c.-485C>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066685 | c.-495_-494delGGinsCC | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066687 | c.-496G>T | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066696 | c.-505T>C | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| Rv2752c | 3066707 | c.-516A>G | upstream_gene_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| thyX | 3067319 | c.627G>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067325 | c.621A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067337 | c.609C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067340 | c.606G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067349 | c.597G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067355 | c.591A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067358 | c.588C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067379 | c.567C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067385 | c.561C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067394 | c.552G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067400 | c.546C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067406 | c.540A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067418 | c.528C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067427 | c.519G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067430 | c.516C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067439 | c.507A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067442 | c.504C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067445 | c.501C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067448 | c.498G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067454 | c.492C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067457 | c.489C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067465 | p.Ile161Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067652 | c.294T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067661 | c.285C>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067676 | c.270C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067679 | p.Cys89Leu | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067685 | c.261A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067693 | p.Ile85Val | missense_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067694 | c.252G>C | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067718 | c.228C>G | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067727 | c.219A>C | synonymous_variant | 0.97 | para-aminosalicylic_acid | |
| thyX | 3067739 | c.207T>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067742 | c.204A>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067761 | p.Arg62Lys | missense_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067765 | p.Leu61Ile | missense_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067781 | c.165C>G | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067793 | c.153T>C | synonymous_variant | 0.96 | para-aminosalicylic_acid | |
| thyX | 3067802 | c.144C>G | synonymous_variant | 0.95 | para-aminosalicylic_acid | |
| thyX | 3067814 | c.132T>C | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyX | 3067817 | c.129C>T | synonymous_variant | 0.94 | para-aminosalicylic_acid | |
| thyX | 3067841 | c.105G>T | synonymous_variant | 0.91 | para-aminosalicylic_acid | |
| thyA | 3073836 | c.636C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073839 | c.633T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073854 | c.618C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073863 | c.609T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073887 | p.Ser195Asp | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073892 | c.580T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073905 | c.567C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073925 | c.547T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073929 | c.543T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073944 | c.528C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073953 | c.519T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073956 | c.516G>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073959 | c.513T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073968 | c.504C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073977 | c.495A>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3073989 | c.483T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074001 | c.471C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074004 | c.468T>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074037 | c.435C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074053 | p.Arg140Gln | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074056 | p.Glu139Pro | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074070 | c.402C>T | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyA | 3074076 | c.396C>G | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| ald | 3087659 | c.840G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087672 | p.His285Asp | missense_variant | 1.0 | cycloserine | |
| ald | 3087686 | c.867C>G | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087692 | c.873C>T | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087699 | p.Leu294Met | missense_variant | 1.0 | cycloserine | |
| ald | 3087726 | p.Ala303Ser | missense_variant | 1.0 | cycloserine | |
| ald | 3087729 | p.Ser304Ala | missense_variant | 1.0 | cycloserine | |
| ald | 3087734 | c.915G>T | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087743 | c.924G>C | synonymous_variant | 1.0 | cycloserine | |
| ald | 3087761 | c.942C>G | synonymous_variant | 1.0 | cycloserine | |
| lpqB | 3624356 | c.555C>T | synonymous_variant | 0.83 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624371 | c.540T>G | synonymous_variant | 0.86 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624377 | c.534C>G | synonymous_variant | 0.86 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3624389 | c.522C>G | synonymous_variant | 0.86 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624613 | p.Ser100Gly | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624614 | c.297A>G | synonymous_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624635 | c.276C>T | synonymous_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624646 | c.265T>C | synonymous_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624649 | c.262T>C | synonymous_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624652 | p.Ala87Ser | missense_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624656 | c.255C>T | synonymous_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3624671 | p.Ala80Ser | missense_variant | 0.9 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625027 | c.-117C>G | upstream_gene_variant | 0.92 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625032 | c.1582C>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625054 | c.-144C>T | upstream_gene_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625057 | c.-147C>T | upstream_gene_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
| bedaquiline | Uncertain significance | |||||
| lpqB | 3625066 | c.-156G>A | upstream_gene_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625069 | c.-159T>G | upstream_gene_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625084 | c.-174C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625095 | p.Glu507Gln | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625096 | c.-186C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625117 | c.-207T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625123 | c.-213T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625138 | c.-228C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625147 | c.-237C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625656 | c.958T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625675 | c.-765G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625690 | c.-780T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625699 | c.915C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625717 | c.-807C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| lpqB | 3625762 | c.-852A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625783 | c.-873C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625801 | c.-891G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625849 | c.-939T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625852 | c.762A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625867 | c.747A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625870 | c.-960C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625876 | c.738G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625909 | c.-999T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626400 | p.Ile72Val | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626404 | c.210C>T | synonymous_variant | 0.93 | rifampicin | Not assoc w R - Interim |
| bedaquiline | Not assoc w R - Interim | |||||
| mtrB | 3626407 | c.207C>G | synonymous_variant | 0.94 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626437 | c.177T>C | synonymous_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626443 | c.171T>G | synonymous_variant | 0.93 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626455 | c.159C>G | synonymous_variant | 0.92 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626461 | c.153A>G | synonymous_variant | 0.92 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626470 | c.144A>C | synonymous_variant | 0.92 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626473 | c.141T>G | synonymous_variant | 0.92 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626476 | c.138C>G | synonymous_variant | 0.92 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626488 | c.126C>G | synonymous_variant | 0.91 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626684 | c.-71G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626704 | c.-91C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626711 | c.-98T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626723 | c.-110C>G | upstream_gene_variant | 0.95 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626726 | c.-113T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626750 | c.-137T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626759 | c.591T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626773 | c.-160C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626774 | c.-163_-161delAGGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626777 | c.573C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626786 | c.564A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3626792 | c.558G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626798 | c.-185T>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626804 | c.546A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3626825 | c.525T>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626843 | c.-230G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626846 | c.504G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626849 | c.-236C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626876 | c.-263A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626885 | c.-272A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626890 | c.-277T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3626912 | c.438T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3626924 | c.-311G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626927 | c.-314G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626930 | c.-317A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626933 | c.-320C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626942 | c.-329A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626954 | c.-341C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626957 | c.-344G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626969 | c.-356C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626972 | c.-359A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626987 | c.-374C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3626996 | c.-383G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627023 | c.-410C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627059 | c.-446G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627068 | c.282T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627080 | c.270T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627098 | c.252A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627101 | c.-488C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627110 | c.-497G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627137 | c.-526_-524delTTGinsCTA | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627143 | c.-530G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627167 | c.-554T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627181 | c.-568T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627182 | c.-569T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627187 | c.163T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrA | 3627188 | c.162A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3627197 | c.-584T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627203 | c.-590C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627212 | c.-599C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627218 | c.-605G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627272 | c.-659G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627278 | c.-665G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627287 | c.-674C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627296 | c.-683T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627299 | c.-688_-686delTTGinsCTC | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrA | 3627343 | p.Thr3Ser | missense_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627359 | c.-746T>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3627360 | c.-747G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| fbiB | 3642662 | c.1128C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642668 | c.1134A>T | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642677 | c.1143A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642680 | c.1146A>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642683 | c.1149C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642695 | c.1161G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642707 | c.1173C>G | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642710 | c.1176G>C | synonymous_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| fbiB | 3642711 | p.Leu393Val | missense_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| clofazimine | ||||||
| alr | 3841018 | p.Leu135Val | missense_variant | 1.0 | cycloserine | |
| alr | 3841028 | c.393G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841033 | p.Val130Ile | missense_variant | 1.0 | cycloserine | |
| alr | 3841036 | p.Gln129Glu | missense_variant | 1.0 | cycloserine | |
| alr | 3841037 | c.384G>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841055 | c.366C>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841079 | c.342T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841088 | c.333C>T | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841100 | c.321A>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841106 | c.315T>C | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841112 | p.Asp103Ala | missense_variant | 1.0 | cycloserine | |
| alr | 3841115 | c.306T>G | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841124 | c.297G>A | synonymous_variant | 1.0 | cycloserine | |
| alr | 3841127 | c.294A>G | synonymous_variant | 1.0 | cycloserine | |
| rpoA | 3877494 | p.Glu338Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3877503 | c.1005G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877506 | p.Gly334Ala | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877515 | c.993G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877557 | c.951C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877587 | c.921A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877617 | c.891G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877638 | c.870T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877677 | p.Ala277Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877685 | c.823C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877731 | c.777G>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877737 | c.771G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877758 | c.750G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877815 | c.693C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877865 | c.643C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877872 | c.636C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877875 | c.633T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877887 | c.621G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877900 | p.Ser203Thr | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877905 | c.603A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877908 | p.Asn200Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3877920 | c.588G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877962 | c.546G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3877968 | c.540C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3877989 | c.519A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878001 | c.507A>G | synonymous_variant | 0.98 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878022 | c.486T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878025 | c.483C>T | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878028 | c.480G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878031 | c.477T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878043 | c.465G>C | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878046 | c.462T>A | synonymous_variant | 0.98 | rifampicin | |
| rpoA | 3878055 | c.453A>G | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878061 | c.447G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878067 | c.441C>G | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878070 | c.438T>C | synonymous_variant | 0.95 | rifampicin | |
| rpoA | 3878082 | c.426T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878091 | c.417C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878097 | c.411G>A | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878103 | c.405A>G | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878106 | c.402G>C | synonymous_variant | 0.96 | rifampicin | |
| rpoA | 3878118 | c.390T>C | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878145 | c.363C>G | synonymous_variant | 0.97 | rifampicin | |
| rpoA | 3878157 | c.351C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878166 | c.342C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878169 | c.339G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878184 | c.324C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878187 | c.321C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878193 | c.315T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878205 | c.303T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878217 | c.291A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878229 | c.279C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878264 | p.Ser82Gly | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878271 | c.237T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878283 | p.Glu75Asp | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878295 | c.213A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878298 | c.210A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878304 | c.204G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878313 | c.195G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878322 | c.186A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878331 | c.177A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878334 | c.174T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878337 | c.171T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878346 | c.162T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878364 | c.144A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878370 | c.138T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878376 | c.132G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878384 | c.124C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878385 | c.123C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878391 | c.117T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoA | 3878415 | c.93C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878418 | c.90C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878442 | c.66G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878454 | c.54A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878458 | p.Asn17Ser | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878471 | p.Val13Leu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878472 | p.Asp12Glu | missense_variant | 1.0 | rifampicin | |
| rpoA | 3878484 | c.24C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878490 | c.18C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878496 | c.12A>T | synonymous_variant | 1.0 | rifampicin | |
| rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878746 | c.-239A>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878761 | c.-254G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878764 | c.-257A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878878 | c.-371T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878881 | c.-374C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878889 | c.-382A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878894 | c.-387A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878909 | c.-402A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878914 | c.-407T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878923 | c.-417_-416delGCinsCG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878947 | c.-440G>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878953 | c.-446C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878962 | c.-455G>A | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878968 | c.-461T>C | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3878974 | c.-469_-467delATCinsGTG | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878995 | c.-488A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3878998 | c.-491C>G | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoA | 3879001 | c.-494C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879004 | c.-499_-497delAAGinsCGC | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879013 | c.-506A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879016 | c.-509A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879022 | c.-515G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879037 | c.-530G>A | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879049 | c.-542A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879117 | c.-610C>T | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879145 | c.-638G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879148 | c.-641G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879178 | c.-671T>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 1.0 | rifampicin | |
| rpoA | 3879202 | c.-695T>C | upstream_gene_variant | 1.0 | rifampicin | |
| ddn | 3986630 | c.-214C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986636 | c.-208C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986648 | c.-196C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986665 | c.-179G>C | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986667 | c.-177_-176delCTinsAC | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986681 | c.-163C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986690 | c.-154C>G | upstream_gene_variant | 1.0 | pretomanid | |
| delamanid | ||||||
| ddn | 3986696 | c.-148G>C | upstream_gene_variant | 0.9 | pretomanid | |
| delamanid | ||||||
| clpC1 | 4038368 | c.2337T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038388 | c.2317T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038398 | c.2307G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038403 | c.2302T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038425 | c.2280C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038444 | p.Ala754Lys | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038446 | c.2259T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038456 | p.Val750Glu | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038486 | p.Gly740Asn | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038491 | c.2214C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038502 | p.Ile735Val | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038508 | c.2197C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038518 | c.2187G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038530 | p.Glu725Asp | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038537 | p.Thr723Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038539 | c.2166G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038569 | c.2136C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038575 | c.2130C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038620 | c.2085G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038668 | c.2037G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038677 | c.2028G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038692 | c.2013C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038749 | c.1956C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038782 | c.1923G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038809 | c.1896G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038875 | c.1830C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038884 | c.1821C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038893 | c.1812C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038953 | c.1752A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038956 | c.1749T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038965 | c.1740T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038971 | c.1734T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038974 | c.1731T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4038989 | c.1716T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038997 | c.1708T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039004 | c.1701C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039022 | c.1683A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039025 | c.1680C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039067 | c.1638G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039106 | c.1599G>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039112 | c.1593C>A | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039119 | c.1585_1586delTCinsAG | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039124 | c.1581C>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039190 | c.1515C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039193 | c.1512C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039223 | c.1482C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039238 | c.1467C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039243 | c.1462C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039259 | c.1446G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039262 | c.1443C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039268 | c.1437C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039286 | c.1419T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039298 | c.1407T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039304 | c.1401G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039313 | c.1392C>T | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4039319 | p.Ala462Thr | missense_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039322 | c.1383T>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039328 | c.1377A>C | synonymous_variant | 0.97 | pyrazinamide | |
| clpC1 | 4039338 | p.Thr456Gln | missense_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039361 | c.1344C>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4039382 | c.1323C>T | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039391 | c.1314T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039409 | c.1296T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039412 | c.1293T>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039415 | p.Glu430Asp | missense_variant | 1.0 | pyrazinamide | Uncertain significance |
| clpC1 | 4039430 | c.1275T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039442 | c.1263A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039481 | c.1224T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039484 | c.1221T>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039508 | c.1197G>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039526 | c.1179G>A | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039532 | c.1173C>T | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4039553 | c.1152C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039562 | c.1143C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039565 | c.1140G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039576 | p.Ala377Ser | missense_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039577 | c.1128T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039583 | c.1122C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039601 | c.1104G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039622 | c.1083C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039664 | c.1041G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039670 | c.1035G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039693 | c.1012C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039694 | c.1011G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039739 | c.966C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039742 | c.963C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039805 | c.900C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039831 | c.874T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039850 | c.855T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039865 | c.840T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039898 | c.807C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039931 | c.774T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039937 | c.768G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039943 | c.762G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039946 | c.759A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039949 | c.756G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039952 | c.753T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039955 | c.750G>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039958 | c.747G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039964 | c.741C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040000 | c.705C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040015 | c.690G>A | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040021 | c.684A>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040090 | c.613_615delTCTinsAGC | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040093 | c.612C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040105 | c.600C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040147 | c.558A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040162 | c.543G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040165 | c.540G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040171 | c.534C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040246 | c.459C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040249 | c.456A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040267 | c.438A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040273 | c.432T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040291 | c.414G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040309 | c.396C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040342 | c.363C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040348 | c.357G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040363 | c.342A>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040369 | c.336C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040393 | c.312G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040411 | c.294T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040419 | c.286C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040426 | c.279T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040431 | c.274T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040450 | c.255A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040456 | c.249C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040459 | c.246C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040462 | c.243C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040465 | c.240T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040471 | c.234T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040480 | c.225T>C | synonymous_variant | 0.94 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040486 | c.219G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040495 | c.210C>A | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040522 | c.183T>C | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040525 | c.180C>T | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040531 | c.174T>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040534 | c.171A>G | synonymous_variant | 0.95 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040537 | c.168G>C | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040551 | c.154T>C | synonymous_variant | 0.96 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040561 | c.144A>G | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040573 | c.132T>A | synonymous_variant | 0.96 | pyrazinamide | |
| clpC1 | 4040579 | c.126A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040582 | c.123G>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040588 | c.117T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040591 | c.114C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040597 | c.108C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040654 | c.51G>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040662 | c.43C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| clpC1 | 4040669 | c.36C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040695 | c.10C>A | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040711 | c.-7G>A | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4044138 | c.144T>C | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044150 | c.132A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044156 | c.126A>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044159 | c.123C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044162 | c.120A>G | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044165 | c.117G>A | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044177 | c.105C>G | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| panD | 4044180 | c.102C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044188 | c.94T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044195 | c.87T>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044225 | c.57C>T | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044231 | p.Cys17Gln | missense_variant | 1.0 | pyrazinamide | |
| panD | 4044237 | c.45G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4044264 | c.18G>C | synonymous_variant | 1.0 | pyrazinamide | |
| panD | 4045000 | c.-719A>T | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045001 | c.-720G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045022 | c.-742_-741delTCinsCG | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045028 | c.-747C>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045034 | c.-753A>G | upstream_gene_variant | 1.0 | pyrazinamide | |
| panD | 4045052 | c.-771G>C | upstream_gene_variant | 1.0 | pyrazinamide | |
| glpK | 4138574 | c.1182G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138580 | c.1176C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138583 | c.1173G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138596 | p.Phe387Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138598 | c.1158G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138631 | c.1125C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138640 | c.1116C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138646 | c.1110G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138670 | c.1086G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138682 | c.1074C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138702 | p.Gln352Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138703 | c.1053C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138706 | c.1050C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138714 | p.Ala348Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138715 | c.1041G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138718 | c.1038T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138724 | c.1032A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138751 | c.1005T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138757 | c.999A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139165 | c.591A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139168 | c.588T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139176 | p.Val194Ile | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139177 | c.579T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139183 | c.573T>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139186 | c.570G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4139215 | c.541T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139223 | p.Thr178Ser | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139230 | p.Pro176Ala | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139231 | c.525A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139243 | c.513A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139249 | c.507C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4139255 | c.501G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| embC | 4239336 | c.-527T>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239344 | c.-519G>C | upstream_gene_variant | 1.0 | ethambutol | |
| embC | 4239347 | c.-516C>T | upstream_gene_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4240512 | p.Ser217Thr | missense_variant | 0.91 | ethambutol | |
| embC | 4240516 | c.654G>C | synonymous_variant | 0.91 | ethambutol | |
| embC | 4240519 | c.657T>C | synonymous_variant | 0.91 | ethambutol | |
| embC | 4240525 | c.663C>G | synonymous_variant | 0.91 | ethambutol | |
| embC | 4240642 | c.780G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240645 | c.783G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240657 | c.795G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240660 | c.798C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Not assoc w R |
| embC | 4240678 | c.816T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240681 | c.819G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240685 | p.Thr275Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4240690 | c.828G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240693 | c.831T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240698 | p.Ala279Gly | missense_variant | 1.0 | ethambutol | |
| embC | 4240726 | c.864G>C | synonymous_variant | 0.91 | ethambutol | Not assoc w R - Interim |
| embC | 4240729 | c.867C>G | synonymous_variant | 0.97 | ethambutol | |
| embC | 4240747 | c.885C>T | synonymous_variant | 0.87 | ethambutol | Not assoc w R - Interim |
| embC | 4240759 | c.897C>G | synonymous_variant | 0.88 | ethambutol | |
| embC | 4240765 | c.903C>G | synonymous_variant | 0.88 | ethambutol | |
| embC | 4240775 | p.Glu305Gln | missense_variant | 0.85 | ethambutol | |
| embC | 4240783 | c.921G>C | synonymous_variant | 0.83 | ethambutol | |
| embC | 4241086 | c.1224G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241101 | c.1239G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241121 | p.Ser420Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4241137 | c.1275G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241146 | c.1284C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241153 | p.Ile431Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241158 | c.1296T>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | c.1300T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241394 | p.Lys511Ser | missense_variant | 1.0 | ethambutol | |
| embC | 4241452 | c.1590G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241455 | c.1593C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241461 | c.1599C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241470 | c.1608C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245056 | c.1824C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245060 | c.1828T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245063 | c.1831C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245078 | p.Trp616Val | missense_variant | 1.0 | ethambutol | |
| embA | 4245083 | c.1851A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245089 | c.1857G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245093 | p.Ile621Val | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4245101 | c.1869G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245125 | c.1893G>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245137 | c.1905T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245149 | c.1917C>G | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245182 | c.1950T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245183 | c.1951C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245186 | p.Thr652Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245189 | c.1957C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245198 | p.Leu656Ala | missense_variant | 1.0 | ethambutol | |
| embA | 4245206 | c.1974A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245207 | c.1975T>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245215 | c.1983A>C | synonymous_variant | 1.0 | ethambutol | |
| embA | 4245222 | p.Tyr664Leu | missense_variant | 1.0 | ethambutol | |
| embA | 4245245 | c.2013C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247425 | c.912G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247437 | c.924A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247452 | c.939C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247470 | c.957T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247497 | c.984T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247500 | c.987C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247506 | c.993C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247512 | c.999T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247527 | c.1014G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247539 | c.1026T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247550 | p.Ala346Asp | missense_variant | 1.0 | ethambutol | |
| embB | 4247554 | c.1041T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247566 | c.1053C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247572 | c.1059A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247590 | c.1077A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247629 | c.1116C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247632 | c.1119C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247638 | c.1125G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247677 | c.1164C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4247684 | c.1171T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247722 | c.1209G>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247725 | c.1212G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247729 | p.Gly406Pro | missense_variant | 1.0 | ethambutol | |
| embB | 4247983 | c.1470G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248007 | c.1494C>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248035 | p.Val508Ile | missense_variant | 1.0 | ethambutol | |
| embB | 4248041 | p.Ala510Thr | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248044 | p.Lys511Ala | missense_variant | 1.0 | ethambutol | |
| embB | 4248055 | c.1542G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248064 | c.1551G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248070 | c.1557T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248085 | c.1572T>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248097 | c.1584C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248118 | c.1605T>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248190 | c.1677G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embB | 4248200 | p.Ile563Val | missense_variant | 1.0 | ethambutol | |
| embB | 4248206 | p.Ser565Gly | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4248211 | c.1698G>A | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248220 | c.1707A>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248241 | c.1728C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248277 | c.1764G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248298 | c.1785C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248304 | c.1791G>C | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248316 | c.1803C>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248319 | c.1806A>G | synonymous_variant | 1.0 | ethambutol | |
| embB | 4248322 | c.1809G>C | synonymous_variant | 1.0 | ethambutol |
