TB-Profiler result

Run: ERR4820833
Summary

Run ID: ERR4820833

Sample name:

Date: 01-04-2023 16:54:23

Number of reads: 242034

Percentage reads mapped: 33.12

Strain:

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.14 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.67 streptomycin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.16 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2156007 c.104delA frameshift_variant 0.33 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575280 c.-67delC upstream_gene_variant 0.5
rpoB 761027 c.1221A>G synonymous_variant 0.4
rpoB 761037 c.1231T>C synonymous_variant 0.4
rpoB 761054 c.1248G>C synonymous_variant 0.5
rpoB 761060 c.1254C>G synonymous_variant 0.5
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.25
rpoB 761096 c.1290G>C synonymous_variant 0.29
rpoB 761102 c.1296A>G synonymous_variant 0.29
rpoB 762024 p.Val740Ile missense_variant 0.22
rpoB 762029 c.2223C>G synonymous_variant 0.22
rpoB 762051 p.His749Tyr missense_variant 0.38
rpoB 762057 p.Ile751Val missense_variant 0.38
rpoB 762062 c.2256T>C synonymous_variant 0.5
rpoB 762065 c.2259T>C synonymous_variant 0.5
rpoB 762071 p.Asp755Glu missense_variant 0.5
rpoB 762080 c.2274G>C synonymous_variant 0.5
rpoB 762085 p.Ala760Glu missense_variant 0.5
rpoB 762089 c.2283G>A synonymous_variant 0.38
rpoB 762110 c.2304G>C synonymous_variant 0.33
rpoB 762114 p.Ile770Val missense_variant 0.33
rpoB 762143 c.2337T>C synonymous_variant 0.22
rpoB 762149 c.2343G>C synonymous_variant 0.22
rpoB 762156 p.Val784Ile missense_variant 0.2
rpoB 762167 c.2361T>C synonymous_variant 0.2
rpoB 762185 c.2379G>C synonymous_variant 0.25
rpoB 762194 c.2388G>C synonymous_variant 0.55
rpoB 762200 c.2394C>T synonymous_variant 0.55
rpoB 762212 c.2406G>C synonymous_variant 0.4
rpoB 762218 c.2412T>C synonymous_variant 0.64
rpoB 762233 c.2427G>C synonymous_variant 0.64
rpoB 762234 p.Pro810Ser missense_variant 0.64
rpoB 762239 c.2433G>A synonymous_variant 0.36
rpoB 762245 c.2439G>C synonymous_variant 0.58
rpoB 762254 c.2448T>C synonymous_variant 0.54
rpoB 762293 c.2487T>C synonymous_variant 0.33
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762855 p.Val1017Ile missense_variant 0.3
rpoB 762858 p.Thr1018Ser missense_variant 0.3
rpoC 762863 c.-507T>G upstream_gene_variant 0.2
rpoB 762871 p.Met1022Thr missense_variant 0.2
rpoB 762878 p.Ile1024Met missense_variant 0.17
rpoB 762879 p.Met1025Leu missense_variant 0.42
rpoC 762899 c.-471G>C upstream_gene_variant 0.14
rpoC 762902 c.-468C>T upstream_gene_variant 0.33
rpoC 762911 c.-459C>T upstream_gene_variant 0.35
rpoC 762917 c.-453C>T upstream_gene_variant 0.35
rpoC 762920 c.-450C>T upstream_gene_variant 0.4
rpoC 762926 c.-444C>G upstream_gene_variant 0.13
rpoC 762929 c.-441G>T upstream_gene_variant 0.43
rpoC 762944 c.-426C>T upstream_gene_variant 0.29
rpoC 762947 c.-423C>G upstream_gene_variant 0.13
rpoC 762956 c.-414G>C upstream_gene_variant 0.31
rpoC 762962 c.-408C>T upstream_gene_variant 0.27
rpoC 762971 c.-399G>C upstream_gene_variant 0.15
rpoC 762980 c.-390T>C upstream_gene_variant 0.17
rpoC 762983 c.-387C>T upstream_gene_variant 0.18
rpoC 762989 c.-381G>C upstream_gene_variant 0.33
rpoC 762995 c.-375G>T upstream_gene_variant 0.25
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.27
rpoC 763043 c.-327G>C upstream_gene_variant 0.33
rpoC 763053 c.-317T>C upstream_gene_variant 0.38
rpoC 763070 c.-300T>C upstream_gene_variant 0.43
rpoB 763077 p.Val1091Thr missense_variant 0.5
rpoC 763103 c.-267G>C upstream_gene_variant 0.47
rpoC 763115 c.-255T>C upstream_gene_variant 0.4
rpoB 763119 p.Asn1105Asp missense_variant 0.4
rpoC 763127 c.-243G>C upstream_gene_variant 0.38
rpoC 763133 c.-237G>C upstream_gene_variant 0.33
rpoC 763160 c.-210G>A upstream_gene_variant 0.22
rpoC 763528 c.159G>C synonymous_variant 0.25
rpoC 763531 c.162G>C synonymous_variant 0.25
rpoC 763534 c.165T>C synonymous_variant 0.25
rpoC 763546 c.177A>G synonymous_variant 0.22
rpoC 763550 p.Tyr61Ala missense_variant 0.2
rpoC 763570 c.201G>C synonymous_variant 0.22
rpoC 763578 p.Phe70Tyr missense_variant 0.22
rpoC 763647 p.Gly93Ala missense_variant 0.25
rpoC 763655 p.Glu96Lys missense_variant 0.2
rpoC 763660 c.291T>C synonymous_variant 0.22
rpoC 763666 c.297G>C synonymous_variant 0.2
rpoC 763669 c.300C>G synonymous_variant 0.17
rpoC 763675 c.306C>G synonymous_variant 0.23
rpoC 763696 c.327T>C synonymous_variant 0.16
rpoC 763699 c.330G>T synonymous_variant 0.44
rpoC 763708 c.339G>C synonymous_variant 0.53
rpoC 763714 c.345G>C synonymous_variant 0.44
rpoC 763717 c.348T>C synonymous_variant 0.44
rpoC 763718 p.Leu117Val missense_variant 0.33
rpoC 763723 c.354G>C synonymous_variant 0.44
rpoC 763724 p.Asp119Asn missense_variant 0.44
rpoC 763729 c.360G>C synonymous_variant 0.5
rpoC 763732 c.363C>G synonymous_variant 0.5
rpoC 763735 c.366G>C synonymous_variant 0.5
rpoC 763744 c.375G>C synonymous_variant 0.43
rpoC 763751 p.Ile128Val missense_variant 0.54
rpoC 763772 p.Val135Met missense_variant 0.29
rpoC 764441 p.Ile358Leu missense_variant 0.5
rpoC 764446 p.Asp359Glu missense_variant 0.5
rpoC 764458 c.1089G>C synonymous_variant 0.6
rpoC 764461 c.1092A>G synonymous_variant 0.6
rpoC 764485 c.1116G>C synonymous_variant 0.73
rpoC 764491 c.1122G>T synonymous_variant 0.73
rpoC 764497 c.1128A>G synonymous_variant 0.45
rpoC 764503 c.1134G>T synonymous_variant 0.91
rpoC 764509 c.1140G>C synonymous_variant 0.18
rpoC 764512 c.1143G>C synonymous_variant 0.93
rpoC 764521 c.1152T>C synonymous_variant 0.94
rpoC 764530 c.1161C>T synonymous_variant 0.69
rpoC 764536 c.1167G>C synonymous_variant 0.93
rpoC 764543 p.Thr392Ala missense_variant 0.93
rpoC 764548 c.1179G>T synonymous_variant 0.79
rpoC 764551 c.1182G>C synonymous_variant 0.26
rpoC 764573 p.Leu402Ile missense_variant 0.59
rpoC 764578 c.1209C>G synonymous_variant 0.59
rpoC 764581 c.1212T>C synonymous_variant 0.56
rpoC 764582 p.Leu405Met missense_variant 0.56
rpoC 764593 c.1224C>T synonymous_variant 0.25
rpoC 764602 c.1233C>T synonymous_variant 0.74
rpoC 764605 c.1236G>T synonymous_variant 0.74
rpoC 764611 c.1242G>T synonymous_variant 0.71
rpoC 764626 c.1257C>T synonymous_variant 0.32
rpoC 764632 c.1263T>C synonymous_variant 0.5
rpoC 764647 c.1278C>T synonymous_variant 0.69
rpoC 764650 c.1281G>T synonymous_variant 0.65
rpoC 764653 c.1284G>C synonymous_variant 0.52
rpoC 764656 c.1287C>T synonymous_variant 0.64
rpoC 764662 c.1293G>C synonymous_variant 0.68
rpoC 764665 c.1296C>T synonymous_variant 0.14
rpoC 764677 c.1308C>A synonymous_variant 0.59
rpoC 764678 p.Lys437Gln missense_variant 0.7
rpoC 764683 c.1314G>C synonymous_variant 0.39
rpoC 764692 c.1323C>T synonymous_variant 0.56
rpoC 764706 p.Leu446Gln missense_variant 0.62
rpoC 764713 c.1344G>C synonymous_variant 0.38
rpoC 764731 c.1362G>C synonymous_variant 0.36
rpoC 764737 c.1368G>C synonymous_variant 0.36
rpoC 764746 c.1377G>T synonymous_variant 0.4
rpoC 764755 p.Asp462Glu missense_variant 0.4
rpoC 764758 c.1389C>G synonymous_variant 0.4
rpoC 764760 p.Asn464Ser missense_variant 0.33
rpoC 764764 c.1395T>C synonymous_variant 0.33
rpoC 764767 c.1398G>T synonymous_variant 0.31
rpoC 764776 c.1407C>T synonymous_variant 0.36
rpoC 764785 c.1416C>T synonymous_variant 0.33
rpoC 764791 c.1422C>T synonymous_variant 0.31
rpoC 764797 c.1428G>T synonymous_variant 0.2
rpoC 765923 p.Asn852Ala missense_variant 0.17
rpoC 765937 c.2568T>C synonymous_variant 0.23
rpoC 765940 c.2571A>T synonymous_variant 0.25
rpoC 765947 c.2578T>C synonymous_variant 0.23
rpoC 765952 c.2583G>C synonymous_variant 0.23
rpoC 765958 c.2589C>G synonymous_variant 0.23
rpoC 765962 c.2593T>C synonymous_variant 0.23
rpoC 765967 c.2598C>T synonymous_variant 0.21
rpoC 765988 c.2619G>C synonymous_variant 0.21
rpoC 765991 c.2622C>G synonymous_variant 0.21
rpoC 765994 c.2625A>C synonymous_variant 0.21
rpoC 766003 c.2634G>C synonymous_variant 0.23
rpoC 766009 c.2640G>C synonymous_variant 0.2
rpoC 766354 c.2985C>G synonymous_variant 0.25
rpoC 766366 c.2997C>T synonymous_variant 0.22
rpoC 766369 c.3000C>G synonymous_variant 0.22
rpoC 766378 c.3009C>T synonymous_variant 0.25
rpoC 766381 c.3012C>T synonymous_variant 0.29
rpoC 766384 c.3015A>G synonymous_variant 0.29
rpoC 766390 c.3021C>T synonymous_variant 0.29
rpoC 766426 c.3057C>T synonymous_variant 0.29
rpoC 766429 c.3060C>T synonymous_variant 0.29
rpoC 766432 c.3063T>C synonymous_variant 0.29
rpoC 766434 p.Glu1022Gly missense_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781616 c.57C>G synonymous_variant 0.29
rpsL 781623 p.Ala22Pro missense_variant 0.29
rpsL 781628 c.69T>G synonymous_variant 0.25
rpsL 781638 c.79_80delAGinsTC synonymous_variant 0.22
rpsL 781643 c.84G>C synonymous_variant 0.22
rpsL 781652 c.93T>C synonymous_variant 0.25
rpsL 781655 c.96T>C synonymous_variant 0.29
rpsL 781658 c.99A>G synonymous_variant 0.25
rpsL 781667 c.108C>T synonymous_variant 0.25
rpsL 781682 c.123T>G synonymous_variant 0.25
rpsL 781703 c.144G>T synonymous_variant 0.22
rpsL 781706 c.147T>G synonymous_variant 0.22
rpsL 781709 c.150G>A synonymous_variant 0.25
rpsL 781751 c.192G>C synonymous_variant 0.38
rpsL 781760 c.201T>C synonymous_variant 0.46
rpsL 781766 c.207C>T synonymous_variant 0.5
rpsL 781768 p.Glu70Val missense_variant 0.21
rpsL 781772 c.213C>T synonymous_variant 0.18
rpsL 781793 c.234G>C synonymous_variant 0.14
rpsL 781796 p.Met79Ile missense_variant 0.53
rpsL 781802 c.243G>C synonymous_variant 0.53
rpsL 781805 c.246G>T synonymous_variant 0.32
rpsL 781811 c.252C>T synonymous_variant 0.57
rpsL 781814 c.255C>T synonymous_variant 0.52
rpsL 781817 c.258G>T synonymous_variant 0.52
rpsL 781829 c.270G>C synonymous_variant 0.2
rpsL 781832 c.273T>C synonymous_variant 0.47
rpsL 781835 c.276T>C synonymous_variant 0.26
rpsL 781838 c.279G>T synonymous_variant 0.17
rpsL 781841 c.282C>T synonymous_variant 0.29
rpsL 781845 p.Lys96Arg missense_variant 0.29
rpsL 781851 p.Ile98Val missense_variant 0.36
rpsL 781868 c.309T>C synonymous_variant 0.36
rpsL 781871 c.312G>C synonymous_variant 0.36
fbiC 1305492 c.2562T>C synonymous_variant 0.2
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.75
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.85
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.86
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.18
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.85
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.17
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.72
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.72
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.74
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.14
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.66
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.63
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.4
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.48
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.31
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.47
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.8
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 1.0
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.67
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.5
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.75
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.6
rrs 1472426 n.581T>G non_coding_transcript_exon_variant 0.5
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.4
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 1.0
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 1.0
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 1.0
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 1.0
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 1.0
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 1.0
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 1.0
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 1.0
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 1.0
rrs 1472484 n.639_640insC non_coding_transcript_exon_variant 0.67
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.85
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.75
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.76
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.85
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.88
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.84
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.85
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.53
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.81
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.17
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.84
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.84
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.33
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.16
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.61
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.37
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.61
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.68
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 1.0
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 1.0
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 1.0
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 1.0
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 1.0
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.92
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.45
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.65
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.36
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.62
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.65
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.65
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.65
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.35
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.63
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.68
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.36
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.44
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 1.0
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.34
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.49
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.35
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.93
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.9
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.91
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.94
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.59
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.57
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.93
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.2
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.23
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.98
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.98
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.98
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.31
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.36
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.98
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.87
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.93
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.18
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.68
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.97
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.97
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.44
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.95
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.5
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.41
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.94
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.13
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.96
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.55
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.58
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.14
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.19
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.19
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.18
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.62
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.94
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.95
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.14
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.92
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.73
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.59
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.68
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.75
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.9
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.19
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 1.0
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.56
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.6
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.9
rrl 1474183 n.526T>G non_coding_transcript_exon_variant 0.12
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.79
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.88
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.86
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.9
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.91
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 1.0
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474363 n.706A>T non_coding_transcript_exon_variant 1.0
rrl 1474365 n.708G>C non_coding_transcript_exon_variant 1.0
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.67
rrl 1474384 n.727C>G non_coding_transcript_exon_variant 0.67
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.67
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.43
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.43
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.43
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.43
rrl 1474497 n.840G>T non_coding_transcript_exon_variant 0.38
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.56
rrl 1474503 n.846G>A non_coding_transcript_exon_variant 0.33
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.56
rrl 1474506 n.849C>A non_coding_transcript_exon_variant 0.33
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.33
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.89
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.56
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.33
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.44
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.89
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.44
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.45
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.55
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.45
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.44
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.36
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.3
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 1.0
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.7
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.3
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 1.0
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.62
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.89
rrl 1474806 n.1149A>G non_coding_transcript_exon_variant 0.2
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.18
rrl 1474819 n.1162T>G non_coding_transcript_exon_variant 0.15
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.15
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.91
rrl 1474825 n.1168G>A non_coding_transcript_exon_variant 0.15
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.92
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.62
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.62
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.38
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.15
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.9
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 1.0
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 1.0
rrl 1475079 n.1422T>A non_coding_transcript_exon_variant 1.0
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 1.0
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 1.0
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.67
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 1.0
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0
rrl 1475767 n.2110_2111insT non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.82
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.83
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.83
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.83
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 1.0
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 1.0
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 1.0
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 1.0
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.25
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.58
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.88
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.41
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.88
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.59
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.71
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.71
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.24
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.86
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.14
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.38
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.15
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.67
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.55
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.27
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.36
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.73
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.27
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.15
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.96
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.96
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.89
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.69
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.82
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.8
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.75
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.83
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.28
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.17
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.46
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.36
rrl 1476535 n.2878G>A non_coding_transcript_exon_variant 0.45
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 1.0
rrl 1476536 n.2879G>C non_coding_transcript_exon_variant 1.0
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.27
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.91
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.91
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.33
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.43
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.23
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.89
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.78
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.62
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.22
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.62
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.67
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.89
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.89
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.62
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.89
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.83
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.75
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.89
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.75
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.22
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.57
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.4
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.6
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 1.0
rpsA 1833661 c.120A>G synonymous_variant 0.57
rpsA 1833667 c.126C>T synonymous_variant 0.57
rpsA 1833668 p.Ile43Val missense_variant 0.57
rpsA 1833676 c.135A>G synonymous_variant 0.71
rpsA 1833679 c.138G>C synonymous_variant 0.6
rpsA 1833684 p.Arg48His missense_variant 0.57
rpsA 1833694 c.153G>C synonymous_variant 0.71
rpsA 1833700 c.159C>T synonymous_variant 0.67
rpsA 1833721 c.180A>G synonymous_variant 0.83
rpsA 1833727 c.186G>C synonymous_variant 0.83
rpsA 1833732 p.Pro64Leu missense_variant 0.8
rpsA 1833734 p.Ala65Ser missense_variant 0.6
rpsA 1833742 c.201A>G synonymous_variant 0.8
rpsA 1834189 c.648G>T synonymous_variant 0.29
rpsA 1834195 c.654G>C synonymous_variant 0.5
rpsA 1834216 c.675C>T synonymous_variant 0.25
rpsA 1834234 c.693G>C synonymous_variant 0.75
rpsA 1834240 c.699T>C synonymous_variant 0.7
rpsA 1834246 c.705G>T synonymous_variant 0.4
rpsA 1834249 c.708T>C synonymous_variant 0.8
rpsA 1834258 c.717G>A synonymous_variant 0.25
rpsA 1834261 c.720A>G synonymous_variant 0.91
rpsA 1834264 c.723G>C synonymous_variant 0.83
rpsA 1834294 c.753G>C synonymous_variant 0.55
rpsA 1834298 p.Gln253Glu missense_variant 0.55
rpsA 1834306 c.765T>C synonymous_variant 0.55
rpsA 1834307 p.Asp256Gln missense_variant 0.55
rpsA 1834312 c.771G>A synonymous_variant 0.55
rpsA 1834327 c.786G>T synonymous_variant 0.5
rpsA 1834345 c.804C>T synonymous_variant 0.33
rpsA 1834348 c.807T>C synonymous_variant 0.33
rpsA 1834451 c.910T>C synonymous_variant 0.18
rpsA 1834459 c.918G>C synonymous_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103227 c.-185T>A upstream_gene_variant 0.2
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223053 p.Glu38Lys missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
pncA 2289572 c.-331C>A upstream_gene_variant 0.5
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449966 p.Ala488Val missense_variant 0.25
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612674 c.442delA frameshift_variant 0.15
fbiA 3640522 c.-20delG upstream_gene_variant 0.5
alr 3841262 c.159T>C synonymous_variant 0.4
alr 3841473 c.-53G>A upstream_gene_variant 1.0
clpC1 4038859 p.Arg616Ser missense_variant 0.4
clpC1 4040010 p.Ala232Arg missense_variant 0.29
clpC1 4040015 c.690G>C synonymous_variant 0.29
clpC1 4040021 c.684A>C synonymous_variant 0.33
clpC1 4040033 c.672G>C synonymous_variant 0.33
clpC1 4040036 c.669C>T synonymous_variant 0.33
clpC1 4040063 c.642G>C synonymous_variant 0.29
clpC1 4040066 c.639G>C synonymous_variant 0.33
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247507 p.Trp332Arg missense_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0