TB-Profiler result

Run: SRR18213736
Summary

Run ID: SRR18213736

Sample name:

Date: 03-04-2023 19:27:06

Number of reads: 254893

Percentage reads mapped: 13.16

Strain: lineage3

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.29 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.67 streptomycin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8271 c.972delC frameshift_variant 0.4
gyrA 8590 p.Ile430Thr missense_variant 0.18
gyrA 8765 p.Asp488Glu missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9596 c.2295G>T synonymous_variant 1.0
fgd1 491123 p.Ile114Thr missense_variant 0.15
fgd1 491742 c.960T>C synonymous_variant 1.0
fgd1 491769 c.987A>G synonymous_variant 0.13
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761037 c.1231T>C synonymous_variant 0.29
rpoB 761051 c.1245G>C synonymous_variant 0.29
rpoB 761054 c.1248G>C synonymous_variant 0.29
rpoB 761057 c.1251G>C synonymous_variant 0.29
rpoB 761060 c.1254C>G synonymous_variant 0.29
rpoB 761084 c.1278C>A synonymous_variant 0.4
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.4
rpoB 761096 c.1290G>C synonymous_variant 0.5
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.5
rpoB 761102 c.1296A>G synonymous_variant 0.5
rpoB 761123 c.1317G>T synonymous_variant 0.29
rpoB 761126 c.1320G>C synonymous_variant 0.29
rpoB 761132 c.1326G>C synonymous_variant 0.29
rpoB 761133 c.1327T>C synonymous_variant 0.29
rpoB 761147 c.1341C>T synonymous_variant 0.29
rpoB 761150 c.1344A>T synonymous_variant 0.25
rpoB 761159 c.1353G>C synonymous_variant 0.25
rpoB 761165 c.1359G>C synonymous_variant 0.25
rpoB 762114 p.Ile770Val missense_variant 0.18
rpoB 762122 p.Asp772Glu missense_variant 0.15
rpoB 762125 c.2319G>A synonymous_variant 0.15
rpoB 762126 p.Val774Ser missense_variant 0.15
rpoB 762143 c.2337T>C synonymous_variant 0.21
rpoB 762149 c.2343G>C synonymous_variant 0.21
rpoB 762156 p.Val784Ile missense_variant 0.18
rpoB 762167 c.2361T>C synonymous_variant 0.12
rpoB 762176 c.2370T>C synonymous_variant 0.12
rpoB 762178 p.Arg791Pro missense_variant 0.12
rpoB 762181 p.Asp792Ala missense_variant 0.12
rpoB 762185 c.2379G>C synonymous_variant 0.12
rpoB 762194 c.2388G>C synonymous_variant 0.12
rpoB 762200 c.2394C>T synonymous_variant 0.22
rpoB 762233 c.2427G>C synonymous_variant 0.21
rpoB 762236 c.2430G>C synonymous_variant 0.15
rpoB 762245 c.2439G>C synonymous_variant 0.17
rpoB 762254 c.2448T>C synonymous_variant 0.14
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 762926 c.-444C>G upstream_gene_variant 0.22
rpoC 762929 c.-441G>C upstream_gene_variant 0.22
rpoC 762947 c.-423C>G upstream_gene_variant 0.3
rpoC 762971 c.-399G>C upstream_gene_variant 0.38
rpoC 762980 c.-390T>C upstream_gene_variant 0.38
rpoC 762989 c.-381G>C upstream_gene_variant 0.35
rpoC 762995 c.-375G>C upstream_gene_variant 0.38
rpoB 763005 p.Cys1067Val missense_variant 0.36
rpoB 763014 p.Met1070Leu missense_variant 0.36
rpoB 763017 p.Gln1071Glu missense_variant 0.38
rpoC 763022 c.-348C>T upstream_gene_variant 0.27
rpoC 763028 c.-342T>C upstream_gene_variant 0.38
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.38
rpoC 763043 c.-327G>C upstream_gene_variant 0.38
rpoC 763053 c.-317T>C upstream_gene_variant 0.36
rpoC 763067 c.-303C>G upstream_gene_variant 0.33
rpoC 763070 c.-300T>C upstream_gene_variant 0.31
rpoB 763077 p.Val1091Thr missense_variant 0.27
rpoC 763103 c.-267G>C upstream_gene_variant 0.15
rpoC 763109 c.-261C>T upstream_gene_variant 0.17
rpoB 763180 p.Leu1125Pro missense_variant 0.25
rpoC 763642 c.273G>C synonymous_variant 1.0
rpoC 763648 c.279C>T synonymous_variant 1.0
rpoC 763657 p.Glu96Asp missense_variant 1.0
rpoC 763660 c.291T>G synonymous_variant 0.67
rpoC 763666 c.297G>C synonymous_variant 0.5
rpoC 763675 c.306C>G synonymous_variant 0.75
rpoC 763699 c.330G>T synonymous_variant 0.5
rpoC 763708 c.339G>C synonymous_variant 0.5
rpoC 763714 c.345G>C synonymous_variant 0.43
rpoC 763717 c.348T>C synonymous_variant 0.5
rpoC 763718 p.Leu117Val missense_variant 0.5
rpoC 763723 c.354G>C synonymous_variant 0.5
rpoC 763724 p.Asp119Asn missense_variant 0.5
rpoC 763729 c.360G>C synonymous_variant 0.5
rpoC 763732 c.363C>G synonymous_variant 0.4
rpoC 763735 c.366G>C synonymous_variant 0.4
rpoC 763744 c.375G>C synonymous_variant 0.5
rpoC 763751 p.Ile128Val missense_variant 0.5
rpoC 763772 p.Val135Met missense_variant 0.5
rpoC 764181 p.Asp271Gly missense_variant 1.0
rpoC 764353 c.984G>T synonymous_variant 0.5
rpoC 764359 c.990C>G synonymous_variant 0.43
rpoC 764371 c.1002G>C synonymous_variant 0.43
rpoC 764377 c.1008C>G synonymous_variant 0.43
rpoC 764380 c.1011G>C synonymous_variant 0.43
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.43
rpoC 764404 c.1035C>T synonymous_variant 0.3
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.4
rpoC 764410 c.1041G>C synonymous_variant 0.4
rpoC 764424 p.Asn352Thr missense_variant 0.44
rpoC 764428 c.1059G>A synonymous_variant 0.44
rpoC 764431 c.1062G>C synonymous_variant 0.44
rpoC 764434 c.1065A>G synonymous_variant 0.44
rpoC 764435 c.1066_1068delAGGinsCGT synonymous_variant 0.44
rpoC 764441 p.Ile358Leu missense_variant 0.44
rpoC 764446 p.Asp359Glu missense_variant 0.4
rpoC 764452 c.1083T>C synonymous_variant 0.3
rpoC 764455 c.1086G>C synonymous_variant 0.4
rpoC 764458 c.1089G>C synonymous_variant 0.4
rpoC 764461 c.1092A>G synonymous_variant 0.45
rpoC 764485 c.1116G>C synonymous_variant 0.45
rpoC 764491 c.1122G>T synonymous_variant 0.38
rpoC 764497 c.1128A>G synonymous_variant 0.33
rpoC 764503 c.1134G>T synonymous_variant 0.31
rpoC 764512 c.1143G>C synonymous_variant 0.38
rpoC 764521 c.1152T>C synonymous_variant 0.38
rpoC 764530 c.1161C>T synonymous_variant 0.31
rpoC 764536 c.1167G>C synonymous_variant 0.33
rpoC 764543 p.Thr392Ala missense_variant 0.25
rpoC 764548 c.1179G>C synonymous_variant 0.36
rpoC 764566 c.1197C>G synonymous_variant 0.18
rpoC 764573 p.Leu402Ile missense_variant 0.36
rpoC 764578 c.1209C>G synonymous_variant 0.36
rpoC 764581 c.1212T>C synonymous_variant 0.36
rpoC 764582 p.Leu405Met missense_variant 0.36
rpoC 764593 c.1224C>T synonymous_variant 0.25
rpoC 764602 c.1233C>G synonymous_variant 0.18
rpoC 764605 c.1236G>T synonymous_variant 0.31
rpoC 764611 c.1242G>T synonymous_variant 0.27
rpoC 764626 c.1257C>T synonymous_variant 0.36
rpoC 764632 c.1263T>C synonymous_variant 0.36
rpoC 764677 c.1308C>G synonymous_variant 0.25
rpoC 764678 p.Lys437Gln missense_variant 0.25
rpoC 764692 c.1323C>T synonymous_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775877 c.2604C>T synonymous_variant 0.15
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777572 p.Phe303Leu missense_variant 0.5
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.4
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.57
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.57
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.29
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.3
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.69
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.55
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.57
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.55
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.3
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.19
rrs 1472129 n.284G>A non_coding_transcript_exon_variant 0.19
rrs 1472135 n.290C>G non_coding_transcript_exon_variant 0.14
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.14
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.14
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.94
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.26
rrs 1472153 n.308G>C non_coding_transcript_exon_variant 0.12
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.66
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.62
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.34
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 0.26
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.24
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.6
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.32
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 0.29
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.24
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.92
rrs 1472252 n.407G>C non_coding_transcript_exon_variant 0.13
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.17
rrs 1472256 n.411T>A non_coding_transcript_exon_variant 0.18
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.4
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.5
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.5
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.5
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.67
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.67
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.67
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.67
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.67
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.67
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.67
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.67
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.67
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.6
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.6
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.6
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.6
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.6
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.4
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.6
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.6
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.6
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.67
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.56
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.34
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.52
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.54
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.59
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.61
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.61
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.59
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.28
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.15
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.51
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.68
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.62
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.48
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.88
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.95
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.29
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.67
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.61
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.69
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.3
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.96
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.93
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.64
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.32
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.61
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.89
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.71
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.25
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.18
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.38
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.21
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.66
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.29
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.71
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.68
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.74
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.16
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.76
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.22
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.72
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.67
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.75
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.38
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.57
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.25
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.77
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.13
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.77
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.18
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.19
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 1.0
rrs 1472977 n.1132G>T non_coding_transcript_exon_variant 0.17
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.15
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.27
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.25
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.17
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.86
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.63
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.86
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.13
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.87
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.89
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.9
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.81
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.74
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.74
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.91
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.75
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.94
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.5
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.25
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.91
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.88
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.91
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.88
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.84
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.69
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.8
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.85
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.76
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.83
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.73
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.14
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.13
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.87
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.13
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.87
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.13
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.89
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.7
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.87
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.87
rrs 1473318 n.1473G>A non_coding_transcript_exon_variant 0.15
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.22
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.15
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.15
rrs 1473365 n.1520C>A non_coding_transcript_exon_variant 0.17
rrl 1473384 n.-274A>G upstream_gene_variant 0.33
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 1.0
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.9
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.9
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 1.0
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.86
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 1.0
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474363 n.706A>T non_coding_transcript_exon_variant 1.0
rrl 1474365 n.708G>C non_coding_transcript_exon_variant 1.0
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 1.0
rrl 1474384 n.727C>G non_coding_transcript_exon_variant 1.0
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474483 n.826C>T non_coding_transcript_exon_variant 0.57
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 1.0
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.86
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.67
rrl 1474497 n.840G>A non_coding_transcript_exon_variant 0.67
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.29
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.29
rrl 1474506 n.849C>T non_coding_transcript_exon_variant 0.67
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.86
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.86
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.57
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.67
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.67
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.57
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.86
rrl 1474551 n.894G>A non_coding_transcript_exon_variant 0.75
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.9
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 1.0
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.97
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.97
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.97
rrl 1474674 n.1018delC non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474709 n.1052G>A non_coding_transcript_exon_variant 0.97
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.76
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 1.0
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.93
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.95
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.12
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.94
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.85
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.96
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474801 n.1144G>A non_coding_transcript_exon_variant 0.81
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.88
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.97
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.94
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.84
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.94
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.67
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.94
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.92
rrl 1474933 n.1276A>G non_coding_transcript_exon_variant 0.88
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 0.8
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.67
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.8
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.83
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.86
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.86
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.93
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.88
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.87
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.93
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.86
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.83
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.92
rrl 1475767 n.2110_2111insT non_coding_transcript_exon_variant 0.88
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.88
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.13
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.91
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.84
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.79
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.72
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.9
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.9
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.79
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.89
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.83
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.85
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.77
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.85
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.9
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.89
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.83
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.17
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.8
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.29
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.33
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.67
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.5
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.33
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.67
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.8
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.35
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.48
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.14
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.26
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.29
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.94
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.62
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.62
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.93
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.93
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.91
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.67
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.67
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.67
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.56
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.77
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.96
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.68
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.89
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.95
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.82
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.8
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.98
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.97
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.9
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.98
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.98
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.98
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.98
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.88
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.83
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.81
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.79
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.17
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.72
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.7
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.95
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.25
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.67
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.96
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.89
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.7
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.51
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.9
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.28
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.57
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.4
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.25
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.58
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.29
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.88
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.89
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.94
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.8
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.92
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.46
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.85
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.46
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.31
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.69
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.77
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.17
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.27
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.38
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.57
rpsA 1833679 c.138G>C synonymous_variant 0.12
rpsA 1833685 c.144G>C synonymous_variant 0.12
rpsA 1833700 c.159C>T synonymous_variant 0.12
rpsA 1833928 c.387G>C synonymous_variant 0.4
rpsA 1833949 c.408T>C synonymous_variant 0.38
rpsA 1833970 c.429G>C synonymous_variant 0.25
rpsA 1833976 c.435C>T synonymous_variant 0.33
rpsA 1833979 c.438T>C synonymous_variant 0.3
rpsA 1833994 c.453G>C synonymous_variant 0.3
rpsA 1833997 c.456G>C synonymous_variant 0.3
rpsA 1834000 c.459G>C synonymous_variant 0.3
rpsA 1834009 c.468C>T synonymous_variant 0.27
rpsA 1834012 c.471G>C synonymous_variant 0.25
rpsA 1834015 c.474G>C synonymous_variant 0.27
rpsA 1834024 c.483G>C synonymous_variant 0.3
rpsA 1834025 p.Gln162Ala missense_variant 0.3
rpsA 1834039 c.498C>T synonymous_variant 0.3
rpsA 1834040 p.Lys167Arg missense_variant 0.3
rpsA 1834051 c.510G>A synonymous_variant 0.27
rpsA 1834054 c.513C>G synonymous_variant 0.25
rpsA 1834069 c.528G>C synonymous_variant 0.25
rpsA 1834093 c.552G>C synonymous_variant 0.22
rpsA 1834234 c.693G>C synonymous_variant 0.43
rpsA 1834240 c.699T>C synonymous_variant 0.38
rpsA 1834249 c.708T>C synonymous_variant 0.33
rpsA 1834261 c.720A>G synonymous_variant 0.33
rpsA 1834264 c.723G>C synonymous_variant 0.33
rpsA 1834294 c.753G>C synonymous_variant 0.45
rpsA 1834298 p.Gln253Glu missense_variant 0.45
rpsA 1834306 c.765T>C synonymous_variant 0.42
rpsA 1834307 p.Asp256Gln missense_variant 0.42
rpsA 1834312 c.771G>A synonymous_variant 0.38
rpsA 1834327 c.786G>T synonymous_variant 0.38
rpsA 1834345 c.804C>T synonymous_variant 0.29
rpsA 1834348 c.807T>C synonymous_variant 0.17
rpsA 1834354 c.813G>C synonymous_variant 0.17
rpsA 1834357 c.816T>C synonymous_variant 0.17
rpsA 1834360 c.819G>C synonymous_variant 0.17
rpsA 1834361 c.820T>C synonymous_variant 0.17
rpsA 1834366 c.825A>G synonymous_variant 0.17
rpsA 1834375 c.834G>C synonymous_variant 0.17
rpsA 1834378 c.837T>C synonymous_variant 0.17
rpsA 1834387 c.846C>T synonymous_variant 0.15
rpsA 1834411 c.870T>C synonymous_variant 0.2
rpsA 1834417 c.876G>C synonymous_variant 0.2
rpsA 1834423 c.882G>C synonymous_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155081 p.Thr344Arg missense_variant 0.17
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170769 c.-157C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
kasA 2518953 p.Pro280Leu missense_variant 0.25
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ahpC 2726117 c.-76T>A upstream_gene_variant 1.0
ahpC 2726265 p.Lys25Gln missense_variant 0.29
pepQ 2860506 c.-88G>A upstream_gene_variant 0.4
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449005 p.His168Asn missense_variant 0.22
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642047 c.513G>C synonymous_variant 0.25
clpC1 4038248 c.2457C>T synonymous_variant 1.0
clpC1 4038467 c.2238C>T synonymous_variant 0.33
panD 4044054 c.228G>A synonymous_variant 0.23
embC 4241860 c.1998C>T synonymous_variant 0.33
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4327058 p.Gly139Val missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0