TB-Profiler result

Run: ERR4821214
Summary

Run ID: ERR4821214

Sample name:

Date: 01-04-2023 17:07:37

Number of reads: 664404

Percentage reads mapped: 45.11

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 1.0
lineage1.2.1.2 Indo-Oceanic NA RD239 0.98
lineage1.2.1.2.1 Indo-Oceanic NA RD239 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.25 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.55 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9260 c.1959G>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575368 c.21T>C synonymous_variant 1.0
ccsA 620449 c.560delT frameshift_variant 0.22
rpoB 761030 c.1224G>C synonymous_variant 0.25
rpoB 761037 c.1231T>C synonymous_variant 0.22
rpoB 761051 c.1245G>C synonymous_variant 0.22
rpoB 761054 c.1248G>C synonymous_variant 0.22
rpoB 761057 c.1251G>T synonymous_variant 0.22
rpoB 761060 c.1254C>G synonymous_variant 0.33
rpoB 761084 c.1278C>A synonymous_variant 0.31
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.33
rpoB 761096 c.1290G>C synonymous_variant 0.33
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.27
rpoB 761102 c.1296A>G synonymous_variant 0.31
rpoB 761132 c.1326G>C synonymous_variant 0.23
rpoB 761133 c.1327T>C synonymous_variant 0.23
rpoB 761150 c.1344A>C synonymous_variant 0.15
rpoB 761159 c.1353G>C synonymous_variant 0.15
rpoB 761165 c.1359G>C synonymous_variant 0.15
rpoB 762024 p.Val740Ile missense_variant 0.29
rpoB 762051 p.His749Tyr missense_variant 0.3
rpoB 762057 p.Ile751Val missense_variant 0.32
rpoB 762062 c.2256T>C synonymous_variant 0.35
rpoB 762065 c.2259T>C synonymous_variant 0.38
rpoB 762071 p.Asp755Glu missense_variant 0.33
rpoB 762080 c.2274G>C synonymous_variant 0.4
rpoB 762085 p.Ala760Glu missense_variant 0.46
rpoB 762089 c.2283G>A synonymous_variant 0.43
rpoB 762092 c.2286G>A synonymous_variant 0.36
rpoB 762110 c.2304G>C synonymous_variant 0.36
rpoB 762114 p.Ile770Val missense_variant 0.33
rpoB 762218 c.2412T>C synonymous_variant 0.36
rpoB 762233 c.2427G>C synonymous_variant 0.33
rpoB 762234 p.Pro810Ser missense_variant 0.33
rpoB 762239 c.2433G>A synonymous_variant 0.38
rpoB 762254 c.2448T>C synonymous_variant 0.3
rpoB 762266 c.2460T>C synonymous_variant 0.3
rpoB 762858 p.Thr1018Ser missense_variant 0.15
rpoC 762863 c.-507T>C upstream_gene_variant 0.15
rpoB 762879 p.Met1025Leu missense_variant 0.23
rpoC 762887 c.-483G>C upstream_gene_variant 0.15
rpoC 762893 c.-477C>T upstream_gene_variant 0.13
rpoC 762899 c.-471G>C upstream_gene_variant 0.2
rpoC 762926 c.-444C>G upstream_gene_variant 0.17
rpoC 762929 c.-441G>T upstream_gene_variant 0.27
rpoC 762938 c.-432G>C upstream_gene_variant 0.17
rpoC 762947 c.-423C>G upstream_gene_variant 0.12
rpoC 762962 c.-408C>T upstream_gene_variant 0.21
rpoC 762971 c.-399G>C upstream_gene_variant 0.25
rpoC 762980 c.-390T>C upstream_gene_variant 0.13
rpoC 762983 c.-387C>T upstream_gene_variant 0.14
rpoC 762989 c.-381G>C upstream_gene_variant 0.23
rpoC 762995 c.-375G>T upstream_gene_variant 0.15
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.15
rpoC 763043 c.-327G>C upstream_gene_variant 0.15
rpoC 763053 c.-317T>C upstream_gene_variant 0.27
rpoC 763070 c.-300T>C upstream_gene_variant 0.24
rpoB 763077 p.Val1091Thr missense_variant 0.25
rpoC 763085 c.-285C>A upstream_gene_variant 0.12
rpoC 763103 c.-267G>C upstream_gene_variant 0.27
rpoC 763115 c.-255T>C upstream_gene_variant 0.31
rpoB 763119 p.Asn1105Asp missense_variant 0.33
rpoC 763127 c.-243G>C upstream_gene_variant 0.31
rpoC 763133 c.-237G>C upstream_gene_variant 0.17
rpoC 763531 c.162G>C synonymous_variant 1.0
rpoC 763550 p.Tyr61Ala missense_variant 0.11
rpoC 763570 c.201G>C synonymous_variant 0.18
rpoC 763578 p.Phe70Tyr missense_variant 0.17
rpoC 763622 p.Ala85Ser missense_variant 0.13
rpoC 763642 c.273G>T synonymous_variant 0.12
rpoC 763648 c.279C>T synonymous_variant 0.17
rpoC 763654 c.285C>T synonymous_variant 0.16
rpoC 763657 p.Glu96Asp missense_variant 0.18
rpoC 763666 c.297G>C synonymous_variant 0.17
rpoC 763675 c.306C>G synonymous_variant 0.19
rpoC 763699 c.330G>T synonymous_variant 0.41
rpoC 763708 c.339G>C synonymous_variant 0.33
rpoC 763714 c.345G>C synonymous_variant 0.41
rpoC 763717 c.348T>C synonymous_variant 0.4
rpoC 763718 p.Leu117Val missense_variant 0.39
rpoC 763723 c.354G>C synonymous_variant 0.26
rpoC 763724 p.Asp119Asn missense_variant 0.26
rpoC 763729 c.360G>C synonymous_variant 0.39
rpoC 763732 c.363C>G synonymous_variant 0.31
rpoC 763735 c.366G>C synonymous_variant 0.29
rpoC 763744 c.375G>C synonymous_variant 0.33
rpoC 763751 p.Ile128Val missense_variant 0.43
rpoC 763772 p.Val135Met missense_variant 0.32
rpoC 763781 p.Ser138Ala missense_variant 0.18
rpoC 763884 p.Ala172Val missense_variant 1.0
rpoC 763886 c.517C>A synonymous_variant 1.0
rpoC 764485 c.1116G>C synonymous_variant 0.44
rpoC 764491 c.1122G>T synonymous_variant 0.44
rpoC 764497 c.1128A>G synonymous_variant 0.47
rpoC 764503 c.1134G>T synonymous_variant 0.4
rpoC 764509 c.1140G>C synonymous_variant 0.44
rpoC 764512 c.1143G>C synonymous_variant 0.41
rpoC 764521 c.1152T>C synonymous_variant 0.41
rpoC 764524 c.1155C>T synonymous_variant 0.35
rpoC 764530 c.1161C>T synonymous_variant 0.33
rpoC 764533 c.1164C>T synonymous_variant 0.33
rpoC 764536 c.1167G>C synonymous_variant 0.3
rpoC 764543 p.Thr392Ala missense_variant 0.32
rpoC 764548 c.1179G>T synonymous_variant 0.4
rpoC 764566 c.1197C>G synonymous_variant 0.39
rpoC 764573 p.Leu402Ile missense_variant 0.14
rpoC 764578 c.1209C>G synonymous_variant 0.14
rpoC 764581 c.1212T>C synonymous_variant 0.13
rpoC 764582 p.Leu405Met missense_variant 0.14
rpoC 764602 c.1233C>T synonymous_variant 0.5
rpoC 764605 c.1236G>T synonymous_variant 0.54
rpoC 764611 c.1242G>T synonymous_variant 0.61
rpoC 764632 c.1263T>C synonymous_variant 0.65
rpoC 764647 c.1278C>T synonymous_variant 0.66
rpoC 764650 c.1281G>T synonymous_variant 0.65
rpoC 764653 c.1284G>C synonymous_variant 0.68
rpoC 764656 c.1287C>T synonymous_variant 0.65
rpoC 764662 c.1293G>C synonymous_variant 0.68
rpoC 764677 c.1308C>G synonymous_variant 0.64
rpoC 764678 p.Lys437Gln missense_variant 0.64
rpoC 764706 p.Leu446Gln missense_variant 0.54
rpoC 764713 c.1344G>C synonymous_variant 0.53
rpoC 764731 c.1362G>C synonymous_variant 0.6
rpoC 764737 c.1368G>C synonymous_variant 0.38
rpoC 764746 c.1377G>C synonymous_variant 0.25
rpoC 764764 c.1395T>C synonymous_variant 0.29
rpoC 764809 c.1440C>T synonymous_variant 0.83
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 778320 p.Glu54Gly missense_variant 0.15
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781616 c.57C>G synonymous_variant 0.13
rpsL 781623 p.Ala22Pro missense_variant 0.14
rpsL 781628 c.69T>G synonymous_variant 0.14
rpsL 781638 c.79_80delAGinsTC synonymous_variant 0.12
rpsL 781643 c.84G>C synonymous_variant 0.12
rpsL 781652 c.93T>C synonymous_variant 0.13
rpsL 781655 c.96T>C synonymous_variant 0.14
rpsL 781658 c.99A>G synonymous_variant 0.14
rpsL 781682 c.123T>G synonymous_variant 0.13
rpsL 781703 c.144G>T synonymous_variant 0.18
rpsL 781706 c.147T>G synonymous_variant 0.18
rpsL 781709 c.150G>A synonymous_variant 0.18
rpsL 781796 p.Met79Ile missense_variant 0.27
rpsL 781802 c.243G>C synonymous_variant 0.25
rpsL 781811 c.252C>T synonymous_variant 0.25
rpsL 781814 c.255C>T synonymous_variant 0.24
rpsL 781817 c.258G>T synonymous_variant 0.24
rpsL 781832 c.273T>C synonymous_variant 0.29
rpsL 781835 c.276T>C synonymous_variant 0.29
rpsL 781841 c.282C>T synonymous_variant 0.29
rpsL 781845 p.Lys96Arg missense_variant 0.23
rpsL 781851 p.Ile98Val missense_variant 0.23
rpsL 781868 c.309T>C synonymous_variant 0.25
rpsL 781871 c.312G>C synonymous_variant 0.25
rplC 800654 c.-155T>C upstream_gene_variant 0.15
rplC 800667 c.-142_-140delTCGinsAGC upstream_gene_variant 0.14
rplC 800672 c.-137G>C upstream_gene_variant 0.15
fbiC 1302821 c.-110G>A upstream_gene_variant 1.0
fbiC 1305128 p.Thr733Ile missense_variant 0.12
Rv1258c 1406312 c.1029T>C synonymous_variant 1.0
Rv1258c 1406943 c.397_398insGC frameshift_variant 0.13
Rv1258c 1406946 p.Ala132Gly missense_variant 0.12
Rv1258c 1406948 c.391_392delGC frameshift_variant 0.13
embR 1417019 p.Cys110Tyr missense_variant 1.0
embR 1417119 p.Ser77Pro missense_variant 0.13
atpE 1460907 c.-138T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.56
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.83
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.91
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.92
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.85
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.86
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.87
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.89
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.82
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.8
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.99
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.66
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.8
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.89
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.6
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.86
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.67
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.71
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.57
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.71
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.67
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.6
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.67
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.67
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.67
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.67
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.67
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.67
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.67
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.43
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.5
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.46
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.45
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.68
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.7
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.2
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.73
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.77
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.68
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.18
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.98
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.99
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.25
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.76
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.76
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.32
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.38
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.84
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.86
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.33
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.53
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.31
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.29
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.56
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.46
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.17
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.38
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.24
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.56
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.42
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.54
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.51
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.51
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.51
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.51
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.46
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.47
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.93
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.51
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.85
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.44
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 0.33
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.93
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.76
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.92
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.87
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.94
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.83
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.11
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.96
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.74
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.75
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.97
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.98
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.98
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.97
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.77
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.86
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.96
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.92
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.95
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.76
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.96
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.96
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.96
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.81
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.9
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.76
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.91
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.93
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.89
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.91
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.86
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.87
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.91
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.2
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.95
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.75
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.97
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.12
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.12
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.91
rrl 1473384 n.-274A>G upstream_gene_variant 0.5
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 1.0
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 1.0
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.96
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.96
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.93
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.97
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.97
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.9
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.7
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.67
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.67
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.62
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.62
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.5
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.75
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.57
rrl 1474468 n.811G>A non_coding_transcript_exon_variant 0.25
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.25
rrl 1474479 n.822A>C non_coding_transcript_exon_variant 0.22
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.22
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.78
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.6
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.54
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.54
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.57
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.77
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.57
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.27
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.2
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.73
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.21
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.25
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.5
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.18
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.33
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.89
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.83
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.75
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.89
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.27
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.58
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.8
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.7
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.78
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.89
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.78
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.57
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.73
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.62
rrl 1474753 n.1096delA non_coding_transcript_exon_variant 0.75
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.92
rrl 1474766 n.1109A>G non_coding_transcript_exon_variant 0.13
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.19
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.19
rrl 1474783 n.1126G>T non_coding_transcript_exon_variant 0.12
rrl 1474785 n.1128T>C non_coding_transcript_exon_variant 0.11
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.81
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.14
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.94
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.88
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.93
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.59
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.24
rrl 1474852 n.1195T>C non_coding_transcript_exon_variant 0.17
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.86
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.8
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.75
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.67
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.67
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 1.0
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 1.0
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 1.0
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 1.0
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 1.0
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 1.0
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 1.0
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 1.0
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 1.0
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 1.0
rrl 1475715 n.2058G>T non_coding_transcript_exon_variant 0.5
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 1.0
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.36
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 0.33
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.85
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.75
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.53
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.35
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.31
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.88
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.88
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.39
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.8
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.71
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.47
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.71
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.62
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.71
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.58
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.55
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.64
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.64
rrl 1475995 n.2338G>C non_coding_transcript_exon_variant 0.44
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.38
rrl 1475998 n.2341C>G non_coding_transcript_exon_variant 0.38
rrl 1476000 n.2343G>A non_coding_transcript_exon_variant 0.33
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.56
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.15
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.14
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.45
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.14
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.77
rrl 1476187 n.2530T>C non_coding_transcript_exon_variant 0.15
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.88
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.83
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.92
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.31
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.69
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.62
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.55
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.36
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.4
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.67
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.18
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.27
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.13
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.99
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.98
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.9
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.88
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.96
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.77
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.82
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.65
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.62
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.31
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.36
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.45
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.57
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.13
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.21
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.31
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.57
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.62
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.4
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.29
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.58
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.8
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.75
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.7
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.74
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.67
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.86
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.77
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.18
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.77
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.8
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.71
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.7
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.5
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.47
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.13
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.3
rrl 1476682 n.3026delT non_coding_transcript_exon_variant 0.22
inhA 1674162 c.-40C>T upstream_gene_variant 1.0
inhA 1674497 p.Pro99Leu missense_variant 0.15
rpsA 1834183 c.642T>C synonymous_variant 0.15
rpsA 1834189 c.648G>T synonymous_variant 0.33
rpsA 1834195 c.654G>C synonymous_variant 0.38
rpsA 1834228 c.687C>T synonymous_variant 0.46
rpsA 1834231 c.690T>C synonymous_variant 0.38
rpsA 1834234 c.693G>C synonymous_variant 0.53
rpsA 1834240 c.699T>C synonymous_variant 0.48
rpsA 1834246 c.705G>T synonymous_variant 0.58
rpsA 1834249 c.708T>C synonymous_variant 0.58
rpsA 1834261 c.720A>G synonymous_variant 0.62
rpsA 1834264 c.723G>C synonymous_variant 0.61
rpsA 1834294 c.753G>C synonymous_variant 0.55
rpsA 1834298 p.Gln253Glu missense_variant 0.55
rpsA 1834306 c.765T>C synonymous_variant 0.52
rpsA 1834307 p.Asp256Gln missense_variant 0.5
rpsA 1834312 c.771G>A synonymous_variant 0.52
rpsA 1834327 c.786G>T synonymous_variant 0.54
rpsA 1834345 c.804C>T synonymous_variant 0.44
rpsA 1834348 c.807T>C synonymous_variant 0.38
rpsA 1834354 c.813G>C synonymous_variant 0.31
rpsA 1834357 c.816T>C synonymous_variant 0.29
rpsA 1834360 c.819G>C synonymous_variant 0.29
rpsA 1834361 c.820T>C synonymous_variant 0.29
rpsA 1834366 c.825A>C synonymous_variant 0.31
rpsA 1834375 c.834G>C synonymous_variant 0.29
rpsA 1834378 c.837T>C synonymous_variant 0.31
rpsA 1834387 c.846C>T synonymous_variant 0.29
rpsA 1834395 p.Arg285Gln missense_variant 0.29
rpsA 1834397 p.His286Ala missense_variant 0.27
rpsA 1834411 c.870T>C synonymous_variant 0.35
rpsA 1834417 c.876G>C synonymous_variant 0.21
rpsA 1834423 c.882G>C synonymous_variant 0.2
rpsA 1834427 p.Ile296Val missense_variant 0.2
rpsA 1834435 c.894G>C synonymous_variant 0.2
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.18
rpsA 1834456 c.915T>C synonymous_variant 0.19
rpsA 1834459 c.918G>C synonymous_variant 0.19
rpsA 1834465 c.924T>C synonymous_variant 0.19
rpsA 1834468 c.927A>G synonymous_variant 0.19
rpsA 1834477 c.936C>T synonymous_variant 0.2
rpsA 1834486 p.Glu315Asp missense_variant 0.19
rpsA 1834607 p.Arg356Cys missense_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102050 c.993T>C synonymous_variant 0.11
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2154843 c.1269T>C synonymous_variant 0.15
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169074 c.1539T>C synonymous_variant 0.25
Rv1979c 2221756 p.Ile470Thr missense_variant 0.11
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2222750 c.415C>T synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2519048 p.Gly312Ser missense_variant 1.0
eis 2715524 c.-192G>A upstream_gene_variant 0.17
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
ribD 2986947 p.Asp37Asn missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086987 p.Gln56His missense_variant 0.17
fbiD 3339417 c.300A>G synonymous_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474344 p.Asn113Ser missense_variant 0.18
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3474806 p.Met267Thr missense_variant 0.11
fprA 3475159 p.Asn385Asp missense_variant 1.0
whiB7 3568488 c.191delG frameshift_variant 1.0
fbiB 3640557 c.-978T>C upstream_gene_variant 1.0
clpC1 4038826 p.Ile627Val missense_variant 0.12
clpC1 4038830 c.1875C>T synonymous_variant 0.13
clpC1 4038836 c.1869G>C synonymous_variant 0.13
clpC1 4038839 c.1866G>C synonymous_variant 0.14
clpC1 4038842 c.1863G>C synonymous_variant 0.12
clpC1 4038860 c.1845G>C synonymous_variant 0.12
clpC1 4038872 c.1833C>G synonymous_variant 0.13
clpC1 4038878 c.1827A>G synonymous_variant 0.21
clpC1 4038881 c.1824C>T synonymous_variant 0.14
clpC1 4038884 c.1821C>T synonymous_variant 0.14
clpC1 4038890 p.Glu605Asp missense_variant 0.17
clpC1 4038896 c.1809C>T synonymous_variant 0.15
clpC1 4038905 c.1800A>C synonymous_variant 0.13
clpC1 4039814 c.891C>G synonymous_variant 0.2
clpC1 4039817 c.888A>T synonymous_variant 0.2
clpC1 4039820 c.885T>C synonymous_variant 0.2
clpC1 4039823 c.882T>G synonymous_variant 0.2
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.27
clpC1 4039838 p.Leu289Ile missense_variant 0.25
clpC1 4039850 c.855T>C synonymous_variant 0.17
clpC1 4039853 c.852G>C synonymous_variant 0.17
clpC1 4039856 p.Ile283Met missense_variant 0.17
clpC1 4039865 c.840T>C synonymous_variant 0.25
clpC1 4039874 p.Asn277Lys missense_variant 0.18
clpC1 4039881 p.Glu275Gly missense_variant 0.15
clpC1 4040063 c.642G>C synonymous_variant 0.25
clpC1 4040066 c.639G>C synonymous_variant 0.25
clpC1 4040090 c.615T>C synonymous_variant 0.29
clpC1 4040117 c.588A>G synonymous_variant 0.22
clpC1 4040125 p.Glu194Gln missense_variant 0.2
clpC1 4040517 p.Val63Ala missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 1.0
embC 4242210 p.Glu783Gly missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243580 c.348G>A synonymous_variant 1.0
embA 4244420 c.1188G>C synonymous_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247578 c.1065G>A synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4248609 p.Ile699Thr missense_variant 0.18
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ubiA 4269864 c.-32delG upstream_gene_variant 1.0
whiB6 4338361 p.Arg54Gln missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0