Run ID: SRR29097023
Sample name:
Date: 2025-02-11T14:58:50.533920
Number of reads: 65325
Percentage reads mapped: 49.69
Median coverage: 0.0
Strain: lineage4.9
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage4 | Euro-American | None | 0.98 |
| lineage4.9 | Euro-American (H37Rv-like) | None | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| streptomycin | ||||
| fluoroquinolones | ||||
| moxifloxacin | ||||
| ofloxacin | ||||
| levofloxacin | ||||
| ciprofloxacin | ||||
| aminoglycosides | ||||
| amikacin | ||||
| capreomycin | ||||
| kanamycin | ||||
| cycloserine | ||||
| ethionamide | ||||
| clofazimine | ||||
| para-aminosalicylic_acid | ||||
| delamanid | ||||
| bedaquiline | ||||
| linezolid |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrA | 7412 | c.111C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7421 | c.120G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7424 | c.123G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7427 | c.126G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7436 | c.135C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7442 | c.141G>T | synonymous_variant | 0.97 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7463 | c.162G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7466 | c.165G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7496 | c.195C>G | synonymous_variant | 0.98 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7514 | c.213C>G | synonymous_variant | 0.98 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7517 | c.216G>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7520 | c.219G>C | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7523 | c.222C>A | synonymous_variant | 0.95 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7526 | c.225G>C | synonymous_variant | 0.95 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7559 | c.258G>A | synonymous_variant | 0.92 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 7571 | c.270G>C | synonymous_variant | 0.89 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7574 | c.273G>C | synonymous_variant | 0.88 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
| moxifloxacin | Not assoc w R | |||||
| gyrA | 9227 | c.1926C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9230 | c.1929T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9233 | c.1932C>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9236 | c.1935G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9242 | c.1941A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9252 | p.Val651Ile | missense_variant | 1.0 | levofloxacin | Uncertain significance |
| moxifloxacin | Uncertain significance | |||||
| gyrA | 9267 | p.Asn656Gly | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9281 | c.1980C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9284 | c.1983T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9296 | c.1995T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9299 | c.1998G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9323 | c.2022C>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9335 | c.2034G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9356 | c.2055G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9362 | c.2061C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9377 | c.2076A>G | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9383 | c.2082T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| gyrA | 9386 | c.2085T>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| gyrA | 9395 | c.2094G>C | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| ccsA | 620604 | c.714C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620607 | c.717T>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620625 | c.735A>C | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620631 | c.741T>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620634 | c.744C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620648 | p.Glu253Gly | missense_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| ccsA | 620652 | c.762C>G | synonymous_variant | 1.0 | kanamycin | |
| capreomycin | ||||||
| amikacin | ||||||
| rpoB | 761240 | c.1434C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761249 | c.1443A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761255 | c.1449T>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761258 | c.1452G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761261 | c.1455G>C | synonymous_variant | 0.95 | rifampicin | Not assoc w R - Interim |
| rpoB | 761282 | c.1476C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761318 | c.1512G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761327 | c.1521A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761330 | c.1524G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761333 | c.1527G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761345 | c.1539G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761346 | p.Val514Asn | missense_variant | 1.0 | rifampicin | |
| rpoB | 761354 | c.1548C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761360 | c.1554T>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761369 | p.Glu521Asp | missense_variant | 1.0 | rifampicin | |
| rpoB | 761374 | p.Val523Glu | missense_variant | 1.0 | rifampicin | |
| rpoB | 761408 | c.1602G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761414 | c.1608A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761561 | c.1755C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761564 | c.1758G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761612 | c.1806G>T | synonymous_variant | 0.97 | rifampicin | Not assoc w R - Interim |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761657 | c.1851C>A | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761669 | c.1863C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761675 | c.1869G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761690 | c.1884G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761711 | c.1905C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761712 | p.Val636Ile | missense_variant | 0.94 | rifampicin | |
| rpoB | 761723 | p.Glu639Asp | missense_variant | 1.0 | rifampicin | Not assoc w R |
| rpoB | 761724 | p.Glu640Lys | missense_variant | 1.0 | rifampicin | |
| rpoB | 761728 | p.Ser641Thr | missense_variant | 1.0 | rifampicin | |
| rpoB | 761732 | c.1926C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoB | 761744 | c.1938G>A | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765611 | p.His748Ser | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765625 | c.2256C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765628 | c.2259G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765635 | p.Val756Leu | missense_variant | 1.0 | rifampicin | |
| rpoC | 765640 | c.2271A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765871 | c.2502T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765875 | p.Val836Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoC | 765934 | c.2565C>T | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765967 | c.2598C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765973 | c.2604C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765979 | c.2610C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765982 | c.2613C>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 765991 | c.2622C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 765994 | c.2625A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpoC | 766003 | c.2634G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 766009 | c.2640G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781877 | c.318T>A | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781898 | c.339A>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781907 | c.348T>C | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781916 | c.357T>G | synonymous_variant | 1.0 | streptomycin | |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 | streptomycin | Uncertain significance |
| inhA | 1674342 | c.141T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674353 | p.Thr51Ile | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674368 | p.Ala56Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674370 | p.Lys57Pro | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674375 | c.174C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674399 | c.198A>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674403 | p.Glu68Asn | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674414 | c.213G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674416 | p.Ala72Asp | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674419 | p.Ser73Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674421 | c.220T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674428 | p.Gly76Asp | missense_variant | 1.0 | isoniazid | Uncertain significance |
| ethionamide | Uncertain significance | |||||
| inhA | 1674435 | c.234G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674443 | p.Ala81Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674452 | p.Ala84Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674471 | c.270G>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674480 | c.279T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674534 | c.333G>C | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| inhA | 1674539 | p.Tyr113Phe | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674549 | c.348G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674550 | p.Ser117Ala | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674573 | c.372G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674576 | c.375T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674579 | c.378G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674585 | c.384T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674589 | p.Met130Leu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674597 | c.396G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674600 | c.399G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674618 | c.417C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674624 | c.423A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674628 | p.Ser143Gly | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674654 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674656 | p.Ser152Thr | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674690 | c.489C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674693 | c.492C>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674702 | c.501G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674714 | c.513C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674718 | c.517A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674729 | c.528G>A | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674745 | p.Tyr182Val | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674750 | c.549T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674756 | c.555T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674765 | c.564C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674774 | c.573A>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674777 | c.576C>T | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674801 | c.600T>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674810 | c.609C>G | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674819 | c.618G>C | synonymous_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674825 | c.624C>T | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| inhA | 1674830 | p.Glu210Gly | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674839 | p.Ala213Glu | missense_variant | 1.0 | isoniazid | |
| ethionamide | ||||||
| inhA | 1674855 | c.654C>G | synonymous_variant | 1.0 | isoniazid | Not assoc w R - Interim |
| ethionamide | ||||||
| rpsA | 1834477 | c.936C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834498 | c.957C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834522 | c.981C>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834527 | p.Arg329His | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834540 | c.999G>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
| rpsA | 1834543 | c.1002C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834546 | c.1005T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834552 | c.1011G>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834555 | c.1014T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834558 | c.1017C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834573 | c.1032G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834732 | c.1191T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834738 | c.1197A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834747 | c.1206A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834751 | p.Leu404Ile | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834756 | c.1215G>A | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834759 | c.1218A>T | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834765 | p.Glu408Asp | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834775 | p.Ala412Thr | missense_variant | 1.0 | pyrazinamide | |
| rpsA | 1834780 | c.1239A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834786 | c.1245A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834789 | c.1248T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834792 | c.1251G>C | synonymous_variant | 1.0 | pyrazinamide | |
| tsnR | 1853361 | c.-245T>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853370 | c.-236_-234delGCAinsTCC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853375 | c.-231G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853387 | c.-219T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853390 | c.-216G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853394 | c.-212_-211delCTinsGC | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853420 | c.-186T>G | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853429 | c.-177G>C | upstream_gene_variant | 1.0 | linezolid | |
| tsnR | 1853432 | c.-174G>C | upstream_gene_variant | 1.0 | linezolid | |
| kasA | 2517917 | c.-198G>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517926 | c.-189G>A | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517941 | c.-174C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517950 | c.-165C>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517989 | c.-126T>G | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2517992 | c.-123C>T | upstream_gene_variant | 1.0 | isoniazid | |
| kasA | 2518561 | c.447T>G | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518567 | c.453G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518573 | c.459G>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518574 | p.Ile154Val | missense_variant | 1.0 | isoniazid | |
| kasA | 2518588 | c.474T>C | synonymous_variant | 1.0 | isoniazid | |
| kasA | 2518591 | c.477G>C | synonymous_variant | 1.0 | isoniazid | |
| thyX | 3067844 | c.102G>A | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067847 | p.Pro33Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067850 | c.96A>C | synonymous_variant | 1.0 | para-aminosalicylic_acid | |
| thyX | 3067869 | p.Thr26Ser | missense_variant | 1.0 | para-aminosalicylic_acid | |
| lpqB | 3625678 | c.-768C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625683 | c.-773C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625687 | c.-777G>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625720 | c.-810G>A | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| lpqB | 3625723 | c.-813C>G | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625729 | c.885A>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625747 | c.867G>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625755 | p.Ala287Thr | missense_variant | 1.0 | rifampicin | Uncertain significance |
| bedaquiline | ||||||
| mtrB | 3625762 | c.852A>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625765 | c.849C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625768 | c.-858G>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625774 | c.840G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625806 | c.808A>C | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| mtrB | 3625819 | c.795G>A | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625822 | c.-912C>T | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| mtrB | 3625837 | c.777C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R - Interim |
| bedaquiline | ||||||
| lpqB | 3625852 | c.-942A>C | upstream_gene_variant | 1.0 | rifampicin | |
| bedaquiline | ||||||
| glpK | 4138565 | c.1191G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138568 | c.1188A>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138571 | c.1185C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138574 | c.1182G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138580 | c.1176C>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138598 | c.1158G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138601 | c.1155G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138606 | c.1150T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138607 | c.1149G>A | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138610 | c.1146C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138631 | c.1125C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138634 | c.1122G>T | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138643 | c.1113A>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | ||||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138654 | c.1102C>T | synonymous_variant | 1.0 | levofloxacin | Not assoc w R - Interim |
| moxifloxacin | Not assoc w R - Interim | |||||
| isoniazid | Not assoc w R - Interim | |||||
| streptomycin | Not assoc w R - Interim | |||||
| rifampicin | Not assoc w R - Interim | |||||
| ethambutol | Not assoc w R - Interim | |||||
| glpK | 4138655 | c.1101G>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138661 | c.1095T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138676 | c.1080T>C | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| glpK | 4138682 | c.1074C>G | synonymous_variant | 1.0 | levofloxacin | |
| moxifloxacin | ||||||
| isoniazid | ||||||
| streptomycin | ||||||
| rifampicin | ||||||
| ethambutol | ||||||
| embC | 4240945 | c.1083T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240951 | c.1089C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240954 | c.1092T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240960 | c.1098G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240966 | c.1104G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240979 | p.Thr373Gln | missense_variant | 1.0 | ethambutol | |
| embC | 4240990 | c.1128A>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4240996 | c.1134G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241002 | c.1140G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241017 | c.1155T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241023 | c.1161T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241024 | p.Val388Phe | missense_variant | 1.0 | ethambutol | |
| embC | 4241039 | p.Asp393Asn | missense_variant | 1.0 | ethambutol | |
| embC | 4241047 | c.1185C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241050 | c.1188T>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241053 | c.1191G>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241071 | c.1209C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241084 | p.Leu408Ala | missense_variant | 1.0 | ethambutol | |
| embC | 4241095 | c.1233C>T | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241125 | c.1263G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241131 | c.1269G>A | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241135 | p.Val425Leu | missense_variant | 1.0 | ethambutol | |
| embC | 4241140 | c.1278A>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241141 | p.Ile427Phe | missense_variant | 1.0 | ethambutol | |
| embC | 4241158 | c.1296T>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241161 | c.1299C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241162 | p.Leu434Met | missense_variant | 1.0 | ethambutol | |
| embC | 4241167 | c.1305C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241168 | c.1306C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
| embC | 4241185 | c.1323G>C | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241188 | c.1326C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241194 | c.1332C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241215 | c.1353C>G | synonymous_variant | 1.0 | ethambutol | |
| embC | 4241224 | c.1362G>T | synonymous_variant | 1.0 | ethambutol |
