TB-Profiler result

Run: ERR2228838
Summary

Run ID: ERR2228838

Sample name:

Date: 31-03-2023 16:22:35

Number of reads: 739177

Percentage reads mapped: 45.97

Strain: lineage4.8

Drug-resistance: RR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761196 p.Leu464Met missense_variant 0.27 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.62 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.5 kanamycin, capreomycin, aminoglycosides, amikacin
pncA 2289234 c.7delG frameshift_variant 0.17 pyrazinamide, pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6834 p.Asp532Ala missense_variant 0.2
gyrB 7158 c.1931_1933delCCG disruptive_inframe_deletion 0.25
gyrA 7362 p.Glu21Gln missense_variant 0.94
fgd1 491269 p.Tyr163Asn missense_variant 0.25
fgd1 491315 p.Gly178Ala missense_variant 0.29
fgd1 491558 p.Lys259Thr missense_variant 0.25
mshA 575512 c.165A>C synonymous_variant 0.15
mshA 576629 p.Phe428Ile missense_variant 0.22
ccsA 619831 c.-60T>G upstream_gene_variant 0.25
ccsA 620132 p.Leu81Arg missense_variant 0.33
rpoB 761027 c.1221A>C synonymous_variant 0.12
rpoB 761175 c.1369C>T synonymous_variant 0.22
rpoB 761180 c.1374A>T synonymous_variant 0.2
rpoB 761186 p.Glu460Asp missense_variant 0.22
rpoB 761195 c.1389G>C synonymous_variant 0.27
rpoB 761207 c.1401C>T synonymous_variant 0.19
rpoB 761213 c.1407G>T synonymous_variant 0.18
rpoB 761231 c.1425C>T synonymous_variant 0.17
rpoB 761249 c.1443A>G synonymous_variant 0.27
rpoB 762053 c.2247T>C synonymous_variant 0.12
rpoB 762057 p.Ile751Val missense_variant 0.11
rpoB 762062 c.2256T>C synonymous_variant 0.11
rpoB 762071 c.2265C>T synonymous_variant 0.19
rpoB 762209 c.2403C>T synonymous_variant 0.26
rpoB 762218 c.2412T>C synonymous_variant 0.25
rpoB 762233 c.2427G>C synonymous_variant 0.29
rpoB 762236 c.2430G>T synonymous_variant 0.26
rpoB 762245 c.2439G>T synonymous_variant 0.23
rpoB 762254 c.2448T>C synonymous_variant 0.29
rpoB 762257 c.2451C>G synonymous_variant 0.27
rpoB 762284 c.2478G>C synonymous_variant 0.25
rpoB 762287 c.2481C>T synonymous_variant 0.17
rpoB 762290 c.2484C>T synonymous_variant 0.16
rpoB 762296 c.2490G>C synonymous_variant 0.17
rpoB 762878 p.Ile1024Met missense_variant 0.17
rpoB 762879 p.Met1025Leu missense_variant 0.17
rpoC 762899 c.-471G>T upstream_gene_variant 0.27
rpoC 762920 c.-450C>T upstream_gene_variant 0.23
rpoC 762929 c.-441G>C upstream_gene_variant 0.24
rpoC 762959 c.-411G>T upstream_gene_variant 0.24
rpoC 762971 c.-399G>C upstream_gene_variant 0.25
rpoC 762983 c.-387C>T upstream_gene_variant 0.24
rpoC 762989 c.-381G>A upstream_gene_variant 0.18
rpoC 762995 c.-375G>T upstream_gene_variant 0.19
rpoB 763002 c.3197dupA frameshift_variant 0.18
rpoB 763006 c.3201delC frameshift_variant 0.19
rpoB 763017 p.Gln1071Glu missense_variant 0.23
rpoC 763025 c.-345C>T upstream_gene_variant 0.14
rpoC 763339 c.-31T>A upstream_gene_variant 0.2
rpoC 763528 c.159G>A synonymous_variant 0.28
rpoC 763534 c.165T>C synonymous_variant 0.38
rpoC 763537 c.168C>G synonymous_variant 0.36
rpoC 763546 c.177A>G synonymous_variant 0.39
rpoC 763570 c.201G>C synonymous_variant 0.39
rpoC 763573 c.204G>C synonymous_variant 0.36
rpoC 763594 c.225C>T synonymous_variant 0.33
rpoC 763622 p.Ala85Ser missense_variant 0.38
rpoC 763627 p.Lys86Asn missense_variant 0.33
rpoC 763642 c.273G>T synonymous_variant 0.29
rpoC 763648 c.279C>A synonymous_variant 0.22
rpoC 763651 c.282C>T synonymous_variant 0.15
rpoC 763660 c.291T>G synonymous_variant 0.12
rpoC 763666 c.297G>C synonymous_variant 0.12
rpoC 763669 c.300C>G synonymous_variant 0.11
rpoC 763672 c.303C>G synonymous_variant 0.11
rpoC 763817 p.Thr150Pro missense_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 779614 c.-709A>C upstream_gene_variant 0.2
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303124 p.Val65Gly missense_variant 0.27
fbiC 1303243 p.Cys105Ser missense_variant 0.16
fbiC 1303666 p.Thr246Pro missense_variant 0.31
fbiC 1303747 p.Thr273Ala missense_variant 1.0
Rv1258c 1406509 p.Tyr278Asp missense_variant 0.18
Rv1258c 1407039 p.Val101Gly missense_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472009 n.164T>G non_coding_transcript_exon_variant 0.14
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.29
rrs 1472107 n.262A>G non_coding_transcript_exon_variant 0.3
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.29
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.3
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.33
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.33
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.33
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.52
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.54
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.62
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.6
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.57
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.49
rrs 1472368 n.523A>G non_coding_transcript_exon_variant 0.62
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.62
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.63
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.5
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.24
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.31
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.27
rrs 1472507 n.662C>A non_coding_transcript_exon_variant 0.52
rrs 1472522 n.677T>G non_coding_transcript_exon_variant 0.67
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.72
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.7
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.71
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.68
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.68
rrs 1472585 n.740A>C non_coding_transcript_exon_variant 0.67
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.77
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.8
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.75
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.75
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.74
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.7
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.73
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.75
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.79
rrs 1472767 n.922G>C non_coding_transcript_exon_variant 0.76
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.74
rrs 1472812 n.967A>T non_coding_transcript_exon_variant 0.67
rrs 1472954 n.1110delC non_coding_transcript_exon_variant 0.75
rrs 1472958 n.1113_1114insC non_coding_transcript_exon_variant 0.76
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.79
rrs 1472986 n.1141_1142insA non_coding_transcript_exon_variant 0.77
rrs 1472989 n.1145delA non_coding_transcript_exon_variant 0.77
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.81
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.83
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.68
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.37
rrs 1473091 n.1246G>A non_coding_transcript_exon_variant 0.17
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.17
rrs 1473094 n.1249T>G non_coding_transcript_exon_variant 0.17
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.17
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.18
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.18
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.17
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.18
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.18
rrs 1473120 n.1275C>T non_coding_transcript_exon_variant 0.15
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.15
rrs 1473122 n.1277T>G non_coding_transcript_exon_variant 0.15
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.16
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.46
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.64
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.67
rrs 1473226 n.1381C>G non_coding_transcript_exon_variant 0.64
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.58
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.55
rrs 1473288 n.1443C>G non_coding_transcript_exon_variant 0.45
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.46
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.46
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.46
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.47
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.47
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.46
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.44
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.47
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.21
rrl 1473862 n.205C>T non_coding_transcript_exon_variant 0.38
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.39
rrl 1473887 n.230T>G non_coding_transcript_exon_variant 0.38
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.23
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.27
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.27
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 0.33
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.27
rrl 1473959 n.302T>G non_coding_transcript_exon_variant 0.5
rrl 1473964 n.307T>G non_coding_transcript_exon_variant 0.5
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474033 n.376A>T non_coding_transcript_exon_variant 0.33
rrl 1474166 n.509G>T non_coding_transcript_exon_variant 0.27
rrl 1474167 n.510T>C non_coding_transcript_exon_variant 0.27
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.65
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.7
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.59
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.64
rrl 1474218 n.561T>G non_coding_transcript_exon_variant 0.7
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.5
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.15
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.15
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.15
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.14
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.14
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.26
rrl 1474467 n.810A>T non_coding_transcript_exon_variant 0.22
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.29
rrl 1474488 n.831G>A non_coding_transcript_exon_variant 0.35
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.35
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.33
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.41
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.38
rrl 1474516 n.859C>T non_coding_transcript_exon_variant 0.4
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.46
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.42
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.44
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.44
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.48
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.56
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.54
rrl 1474582 n.925T>A non_coding_transcript_exon_variant 0.69
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.32
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.33
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.44
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.38
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.38
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.38
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.35
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.34
rrl 1474799 n.1143delT non_coding_transcript_exon_variant 0.35
rrl 1474803 n.1146_1147insA non_coding_transcript_exon_variant 0.31
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.45
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.47
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.51
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.51
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.54
rrl 1474853 n.1196A>G non_coding_transcript_exon_variant 0.57
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.55
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.25
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.25
rrl 1475510 n.1853A>T non_coding_transcript_exon_variant 0.33
rrl 1475516 n.1859T>A non_coding_transcript_exon_variant 0.22
rrl 1475517 n.1860C>T non_coding_transcript_exon_variant 0.22
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.24
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.41
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.52
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.25
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.23
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.18
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 0.2
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.24
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.29
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.75
rrl 1475877 n.2220C>T non_coding_transcript_exon_variant 0.72
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.71
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.71
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.78
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.81
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.79
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.86
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.88
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.81
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.79
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.76
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.78
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.75
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.75
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.73
rrl 1475991 n.2334T>A non_coding_transcript_exon_variant 0.58
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.58
rrl 1475996 n.2339T>G non_coding_transcript_exon_variant 0.58
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.2
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.2
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.39
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.44
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.63
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.64
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.56
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.51
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.51
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.51
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.49
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.49
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.44
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.39
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.43
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.47
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.43
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.4
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.84
rrl 1476363 n.2706A>G non_coding_transcript_exon_variant 0.84
rrl 1476366 n.2709A>C non_coding_transcript_exon_variant 0.84
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.84
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.84
rrl 1476374 n.2717T>G non_coding_transcript_exon_variant 0.84
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.84
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.78
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.78
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.76
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.54
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.28
fabG1 1673999 p.Asp187Ala missense_variant 0.23
fabG1 1674038 p.Gln200Leu missense_variant 0.23
inhA 1674655 p.Ser152Arg missense_variant 0.22
rpsA 1833554 p.Thr5Pro missense_variant 0.17
rpsA 1833979 c.438T>C synonymous_variant 0.16
rpsA 1833985 c.444G>T synonymous_variant 0.15
rpsA 1833994 c.453G>C synonymous_variant 0.14
rpsA 1834012 c.471G>A synonymous_variant 0.17
rpsA 1834015 c.474G>C synonymous_variant 0.17
rpsA 1834018 c.477C>T synonymous_variant 0.18
rpsA 1834024 c.483G>C synonymous_variant 0.18
rpsA 1834034 p.Ile165Val missense_variant 0.12
rpsA 1834069 c.528G>C synonymous_variant 0.18
rpsA 1834085 p.Asn182Asp missense_variant 0.11
rpsA 1834090 c.549G>T synonymous_variant 0.22
rpsA 1834099 c.558C>G synonymous_variant 0.21
rpsA 1834177 c.636A>C synonymous_variant 0.13
rpsA 1834619 c.1078T>C synonymous_variant 0.12
rpsA 1834624 c.1083G>C synonymous_variant 0.12
rpsA 1834743 p.Asn401Ile missense_variant 0.3
rpsA 1834794 p.Tyr418Ser missense_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154002 p.Leu704Val missense_variant 0.22
katG 2155549 p.Val188Gly missense_variant 0.38
PPE35 2167681 p.Ser978Pro missense_variant 0.25
PPE35 2167921 p.Phe898Leu missense_variant 0.2
PPE35 2167965 p.Ala883Gly missense_variant 0.13
PPE35 2167967 c.2646A>C synonymous_variant 0.14
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2170006 p.Ile203Leu missense_variant 0.29
PPE35 2170631 c.-19C>A upstream_gene_variant 0.14
Rv1979c 2222918 p.Thr83Pro missense_variant 0.17
Rv1979c 2222986 p.Val60Gly missense_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289264 c.-23T>G upstream_gene_variant 0.43
kasA 2518314 p.Pro67Gln missense_variant 0.14
eis 2714764 p.Leu190Arg missense_variant 0.38
ahpC 2726587 p.Asp132Ala missense_variant 0.13
folC 2746253 p.Asp449Ala missense_variant 0.29
ribD 2987010 p.Thr58Pro missense_variant 0.13
Rv2752c 3065350 p.Val281Glu missense_variant 0.33
Rv2752c 3065901 c.291A>C synonymous_variant 0.23
thyX 3067599 p.Val116Gly missense_variant 0.31
thyX 3067776 p.Asn57Thr missense_variant 0.23
thyA 3074154 c.318T>A synonymous_variant 0.2
thyA 3074318 p.Phe52Ile missense_variant 0.33
fbiD 3339703 p.Thr196Pro missense_variant 0.33
Rv3083 3448341 c.-163A>T upstream_gene_variant 0.4
whiB7 3568652 p.Thr10Pro missense_variant 0.23
Rv3236c 3612065 p.Val351Gly missense_variant 0.18
Rv3236c 3612185 p.Phe311Cys missense_variant 0.18
Rv3236c 3612974 p.Ile48Ser missense_variant 0.2
fbiB 3641953 p.Leu140Arg missense_variant 0.25
fbiB 3642280 p.Leu249Arg missense_variant 0.27
fbiB 3642471 p.Met313Leu missense_variant 0.21
rpoA 3878400 c.108T>C synonymous_variant 0.21
rpoA 3878408 p.Leu34Met missense_variant 0.2
rpoA 3878415 c.93C>A synonymous_variant 0.21
rpoA 3878470 p.Val13Ala missense_variant 0.15
rpoA 3878490 c.18C>G synonymous_variant 0.57
clpC1 4038956 c.1749T>G synonymous_variant 0.4
embC 4241043 p.Asn394Thr missense_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243993 p.Asp254Ala missense_variant 0.23
embB 4246761 p.Val83Gly missense_variant 0.19
embB 4247470 p.Tyr319* stop_gained 0.22
aftB 4267010 p.Glu609Asp missense_variant 0.22
aftB 4268370 p.Val156Gly missense_variant 0.29
aftB 4268603 c.234C>T synonymous_variant 0.33
aftB 4268808 p.Val10Gly missense_variant 0.29
aftB 4268861 c.-25T>G upstream_gene_variant 0.2
aftB 4269006 c.-170T>C upstream_gene_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407813 c.390C>T synonymous_variant 0.18
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0