Run ID: fe46ec44-6a2d-4d33-a7fe-81af7261e47d
Sample name:
Date: 25-06-2023 09:39:10
Number of reads: 387015
Percentage reads mapped: 9.27
Median coverage: 6
Strain: lineage3
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage3 | East-African-Indian | RD750 | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | embB | p.His1002Arg | Uncertain significance | |
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | ||||
| amikacin | rrs | n.1402C>A | Uncertain significance | |
| kanamycin | rrs | n.1402C>A | Uncertain significance | |
| capreomycin | rrs | n.1402C>A | Uncertain significance | |
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rrs | 1473247 | n.1402C>A | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance | |
| capreomycin | Uncertain significance | ||||||
| aminoglycosides | Uncertain significance | ||||||
| amikacin | Uncertain significance | ||||||
| embB | 4249518 | p.His1002Arg | missense_variant | 1.0 | ethambutol | Uncertain significance |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 5074 | c.-166A>G | upstream_gene_variant | 0.2 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 5592 | p.Gly118Val | missense_variant | 0.13 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6130 | c.891T>C | synonymous_variant | 0.18 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6139 | c.900G>C | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6160 | c.921C>G | synonymous_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 6178 | c.939C>T | synonymous_variant | 0.17 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7611 | p.Ser104Pro | missense_variant | 0.2 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8395 | p.Tyr365Cys | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8804 | c.1504delG | frameshift_variant | 0.2 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9624 | p.Tyr775His | missense_variant | 0.12 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| mshA | 575535 | p.Gly63Asp | missense_variant | 0.18 | ethionamide | |
| isoniazid | ||||||
| mshA | 575975 | p.Ala210Ser | missense_variant | 0.13 | ethionamide | |
| isoniazid | ||||||
| ccsA | 620242 | p.Cys118Gly | missense_variant | 0.14 | capreomycin | |
| amikacin | ||||||
| rpoB | 759746 | c.-61C>T | upstream_gene_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 759759 | c.-48T>G | upstream_gene_variant | 0.11 | rifampicin | |
| rpoB | 760560 | p.Met252Leu | missense_variant | 0.12 | rifampicin | |
| rpoB | 762347 | c.2541T>C | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 762350 | c.2544C>T | synonymous_variant | 0.12 | rifampicin | |
| rpoB | 762362 | p.Glu852Asp | missense_variant | 0.14 | rifampicin | |
| rpoB | 762369 | c.2563T>C | synonymous_variant | 0.14 | rifampicin | |
| rpoC | 763031 | c.-339T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763793 | p.Glu142* | stop_gained | 0.2 | rifampicin | |
| rpoC | 765004 | c.1635G>T | synonymous_variant | 0.2 | rifampicin | |
| rpoC | 766370 | p.Gln1001Lys | missense_variant | 0.17 | rifampicin | |
| mmpL5 | 776467 | p.Asp672His | missense_variant | 0.2 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778533 | p.Glu125Gln | missense_variant | 0.13 | clofazimine | |
| bedaquiline | ||||||
| mmpL5 | 778576 | c.-96T>C | upstream_gene_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| mmpS5 | 778659 | p.Gly83Ser | missense_variant | 0.17 | clofazimine | |
| bedaquiline | ||||||
| rpsL | 781622 | c.63C>A | synonymous_variant | 0.14 | streptomycin | |
| rplC | 801329 | p.Arg174Leu | missense_variant | 0.17 | linezolid | |
| fbiC | 1303110 | c.180G>T | synonymous_variant | 0.17 | delamanid | |
| fbiC | 1303526 | p.Ser199* | stop_gained | 0.18 | delamanid | |
| fbiC | 1305080 | p.Arg717Pro | missense_variant | 0.11 | delamanid | |
| embR | 1416553 | c.795C>T | synonymous_variant | 0.15 | ethambutol | |
| embR | 1416591 | p.Arg253Trp | missense_variant | 0.12 | ethambutol | |
| embR | 1417371 | c.-24A>C | upstream_gene_variant | 0.12 | ethambutol | |
| embR | 1417438 | c.-91G>T | upstream_gene_variant | 0.12 | ethambutol | |
| embR | 1417461 | c.-114C>G | upstream_gene_variant | 0.18 | ethambutol | |
| rrs | 1472138 | n.293C>T | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472147 | n.302G>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472153 | n.308G>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472164 | n.319G>A | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472164 | n.319G>T | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472177 | n.332C>A | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472177 | n.332C>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472204 | n.359G>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472214 | n.369C>G | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472240 | n.395G>C | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472242 | n.397C>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472251 | n.406G>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472252 | n.407G>A | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472253 | n.408G>T | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472256 | n.411T>A | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472259 | n.414C>A | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472333 | n.488G>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472349 | n.504A>C | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472373 | n.528G>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472374 | n.529T>G | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472382 | n.537G>A | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472389 | n.544G>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472390 | n.545T>A | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472391 | n.546C>T | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472412 | n.567A>C | non_coding_transcript_exon_variant | 0.35 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472414 | n.569C>T | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472435 | n.590T>C | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472439 | n.594C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472517 | n.672T>A | non_coding_transcript_exon_variant | 0.66 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472537 | n.692C>T | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472541 | n.696T>G | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472553 | n.708C>T | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| kanamycin | ||||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472572 | n.727T>C | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472574 | n.729T>C | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472579 | n.734G>A | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472582 | n.737G>A | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472583 | n.738T>A | non_coding_transcript_exon_variant | 0.86 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472584 | n.739A>G | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472591 | n.746G>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472594 | n.749G>C | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472598 | n.753A>T | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472658 | n.813G>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472659 | n.814G>C | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472660 | n.815T>G | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472707 | n.862A>G | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472714 | n.869A>C | non_coding_transcript_exon_variant | 0.8 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472714 | n.869A>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472715 | n.870C>G | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472716 | n.871C>A | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472734 | n.889C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472741 | n.896G>A | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472754 | n.909G>T | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472785 | n.940G>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472803 | n.958T>A | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472824 | n.979T>A | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472827 | n.982G>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472828 | n.983T>C | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472836 | n.991G>C | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472842 | n.997G>A | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472847 | n.1002G>T | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472850 | n.1005T>C | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472887 | n.1042G>C | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472912 | n.1067C>T | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472917 | n.1072G>A | non_coding_transcript_exon_variant | 0.66 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472936 | n.1091C>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472951 | n.1106T>C | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472952 | n.1107T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472953 | n.1108G>A | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472955 | n.1110C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.77 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472958 | n.1113A>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472959 | n.1114T>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472963 | n.1118G>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472973 | n.1128A>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473026 | n.1181T>C | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473051 | n.1206T>C | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473053 | n.1208T>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473062 | n.1217T>A | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473068 | n.1223A>G | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473139 | n.1294T>C | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473148 | n.1303G>A | non_coding_transcript_exon_variant | 0.71 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473163 | n.1318C>T | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473177 | n.1332G>A | non_coding_transcript_exon_variant | 0.7 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473191 | n.1346C>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473192 | n.1347A>G | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473198 | n.1354delC | non_coding_transcript_exon_variant | 0.68 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473202 | n.1357C>T | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473205 | n.1360T>C | non_coding_transcript_exon_variant | 0.37 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473206 | n.1361G>A | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1474582 | n.925T>C | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474583 | n.926C>G | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1474584 | n.927C>G | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1474586 | n.929T>A | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1474594 | n.937G>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474597 | n.940T>A | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474608 | n.951T>G | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474609 | n.952G>C | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1474610 | n.953C>T | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1474782 | n.1125G>A | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474790 | n.1133C>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474803 | n.1146G>A | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474824 | n.1167A>G | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474830 | n.1173A>G | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| rrl | 1474844 | n.1187G>T | non_coding_transcript_exon_variant | 0.35 | linezolid | |
| rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.45 | linezolid | |
| rrl | 1474866 | n.1209C>A | non_coding_transcript_exon_variant | 0.48 | linezolid | |
| rrl | 1474869 | n.1212G>T | non_coding_transcript_exon_variant | 0.52 | linezolid | |
| rrl | 1474875 | n.1218G>A | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| rrl | 1474876 | n.1219T>A | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| rrl | 1475791 | n.2134A>G | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1475803 | n.2146T>C | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1475804 | n.2147G>C | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1475816 | n.2159C>G | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| rrl | 1475817 | n.2160A>G | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| rrl | 1475869 | n.2212C>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475874 | n.2217C>T | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| rrl | 1476016 | n.2362delG | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1476313 | n.2656G>A | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| rrl | 1476336 | n.2679C>T | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| rrl | 1476356 | n.2699C>A | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1476357 | n.2700T>C | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1476359 | n.2702C>G | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| rrl | 1476368 | n.2711T>C | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476381 | n.2724G>C | non_coding_transcript_exon_variant | 0.76 | linezolid | |
| rrl | 1476382 | n.2725A>G | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1476383 | n.2726T>A | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1476383 | n.2726T>G | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1476384 | n.2727G>T | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| rrl | 1476388 | n.2731T>C | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1476408 | n.2751G>A | non_coding_transcript_exon_variant | 0.8 | linezolid | |
| rrl | 1476411 | n.2754G>A | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| rrl | 1476425 | n.2768G>A | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1476428 | n.2771C>A | non_coding_transcript_exon_variant | 0.58 | linezolid | |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| rrl | 1476442 | n.2785T>A | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1476443 | n.2786G>C | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| rrl | 1476443 | n.2786G>T | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| rrl | 1476455 | n.2798C>A | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| rrl | 1476455 | n.2798C>G | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| rrl | 1476456 | n.2799A>T | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1476463 | n.2806C>T | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.88 | linezolid | Uncertain significance |
| rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| rrl | 1476512 | n.2855C>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1476517 | n.2860C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476519 | n.2862C>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476524 | n.2867C>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476530 | n.2873C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.45 | linezolid | |
| rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| inhA | 1674708 | c.508_509delTC | frameshift_variant | 0.14 | ethionamide | |
| isoniazid | ||||||
| tlyA | 1918684 | p.Arg249Gly | missense_variant | 0.13 | capreomycin | |
| katG | 2154183 | c.1929G>T | synonymous_variant | 0.18 | isoniazid | |
| katG | 2156300 | c.-189G>T | upstream_gene_variant | 0.15 | isoniazid | |
| katG | 2156564 | c.-458_-454delCGAAC | upstream_gene_variant | 0.14 | isoniazid | |
| PPE35 | 2167654 | p.Pro987Thr | missense_variant | 0.2 | pyrazinamide | |
| PPE35 | 2169209 | c.1404C>A | synonymous_variant | 0.14 | pyrazinamide | |
| PPE35 | 2169292 | p.Val441Ile | missense_variant | 0.2 | pyrazinamide | |
| PPE35 | 2170811 | c.-199C>T | upstream_gene_variant | 0.17 | pyrazinamide | |
| Rv1979c | 2222094 | p.Ala357Gly | missense_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222193 | c.972G>A | synonymous_variant | 0.13 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222209 | p.Ala319Asp | missense_variant | 0.13 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222343 | c.822G>C | synonymous_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222349 | c.816G>A | synonymous_variant | 0.15 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2222706 | c.459C>G | synonymous_variant | 0.12 | clofazimine | |
| bedaquiline | ||||||
| Rv1979c | 2223202 | c.-38G>T | upstream_gene_variant | 0.18 | clofazimine | |
| bedaquiline | ||||||
| pncA | 2289047 | c.195C>T | synonymous_variant | 1.0 | pyrazinamide | |
| pncA | 2289551 | c.-310C>A | upstream_gene_variant | 0.2 | pyrazinamide | |
| pncA | 2289558 | c.-317C>G | upstream_gene_variant | 0.2 | pyrazinamide | |
| pncA | 2289715 | c.-474C>G | upstream_gene_variant | 0.11 | pyrazinamide | |
| pncA | 2289734 | c.-493C>A | upstream_gene_variant | 0.14 | pyrazinamide | |
| pncA | 2289747 | c.-506A>G | upstream_gene_variant | 0.12 | pyrazinamide | |
| ahpC | 2726105 | c.-88G>A | upstream_gene_variant | 1.0 | isoniazid | Uncertain significance |
| ahpC | 2726269 | p.Val26Gly | missense_variant | 0.2 | isoniazid | |
| ahpC | 2726483 | c.291T>G | synonymous_variant | 0.12 | isoniazid | |
| ahpC | 2726492 | c.300C>T | synonymous_variant | 0.12 | isoniazid | |
| folC | 2747676 | c.-78C>A | upstream_gene_variant | 0.18 | para-aminosalicylic_acid | |
| Rv2752c | 3065480 | p.Phe238Leu | missense_variant | 0.2 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065842 | p.Arg117His | missense_variant | 0.2 | rifampicin | |
| isoniazid | ||||||
| Rv2752c | 3065859 | c.333G>T | synonymous_variant | 0.2 | rifampicin | |
| isoniazid | ||||||
| thyA | 3073951 | p.Val174Ala | missense_variant | 0.13 | para-aminosalicylic_acid | |
| thyA | 3074038 | p.Pro145Arg | missense_variant | 0.12 | para-aminosalicylic_acid | |
| thyA | 3074095 | p.Arg126Pro | missense_variant | 0.17 | para-aminosalicylic_acid | |
| thyA | 3074099 | p.Ser125Pro | missense_variant | 0.14 | para-aminosalicylic_acid | |
| Rv3236c | 3612895 | c.221delG | frameshift_variant | 0.18 | pyrazinamide | |
| Rv3236c | 3613177 | c.-61G>A | upstream_gene_variant | 0.12 | pyrazinamide | |
| fbiB | 3641832 | p.Gly100Trp | missense_variant | 0.18 | delamanid | |
| fbiB | 3641990 | p.Met152Ile | missense_variant | 0.13 | delamanid | |
| fbiB | 3642173 | c.639G>C | synonymous_variant | 0.12 | delamanid | |
| alr | 3841004 | c.417C>T | synonymous_variant | 0.13 | cycloserine | |
| rpoA | 3878115 | p.Lys131Asn | missense_variant | 0.11 | rifampicin | |
| clpC1 | 4039724 | c.981A>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039733 | c.972G>T | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039742 | c.963C>T | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039748 | c.957G>C | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039751 | c.954A>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039757 | c.948A>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039763 | c.942C>T | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039766 | c.939T>C | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039775 | c.930G>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039778 | c.927A>G | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039781 | c.924G>C | synonymous_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039787 | c.918G>C | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039793 | c.912C>G | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039802 | c.903G>T | synonymous_variant | 0.14 | pyrazinamide | |
| clpC1 | 4039814 | c.891C>G | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4039817 | c.888A>C | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039820 | c.885T>G | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4039825 | p.Gly294Arg | missense_variant | 0.15 | pyrazinamide | |
| clpC1 | 4039826 | c.879C>G | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4039829 | c.874_876delTTGinsCTC | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4039889 | c.816G>T | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040324 | c.381G>C | synonymous_variant | 0.2 | pyrazinamide | |
| clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040357 | c.348T>C | synonymous_variant | 0.18 | pyrazinamide | |
| clpC1 | 4040375 | c.330G>C | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040381 | c.324T>C | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.17 | pyrazinamide | |
| clpC1 | 4040390 | c.315C>G | synonymous_variant | 0.14 | pyrazinamide | |
| embC | 4241870 | c.2008_2009insC | frameshift_variant | 0.15 | ethambutol | |
| embC | 4242081 | p.Asn740Ser | missense_variant | 0.18 | ethambutol | |
| embC | 4243088 | p.Asn1076Asp | missense_variant | 0.2 | ethambutol | |
| embB | 4247362 | c.849G>C | synonymous_variant | 0.17 | ethambutol | |
| embB | 4248549 | p.Ala679Asp | missense_variant | 0.15 | ethambutol | |
| embB | 4248554 | p.Gly681Ser | missense_variant | 0.15 | ethambutol | |
| embB | 4249446 | p.Val978Gly | missense_variant | 0.2 | ethambutol | |
| aftB | 4267096 | p.Pro581Thr | missense_variant | 0.18 | capreomycin | |
| amikacin | ||||||
| aftB | 4267195 | p.Pro548Thr | missense_variant | 0.17 | capreomycin | |
| amikacin | ||||||
| aftB | 4267330 | c.1507C>A | synonymous_variant | 0.2 | capreomycin | |
| amikacin | ||||||
| ubiA | 4269276 | p.Phe186Leu | missense_variant | 0.15 | ethambutol | |
| ethA | 4326456 | p.Thr340Pro | missense_variant | 0.15 | ethionamide | |
| gid | 4408336 | c.-134T>G | upstream_gene_variant | 0.17 | streptomycin |
