TB-Profiler result

Run: ERR4820151
Summary

Run ID: ERR4820151

Sample name:

Date: 01-04-2023 16:30:55

Number of reads: 1007482

Percentage reads mapped: 71.41

Strain: lineage4.8

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.2 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.42 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5446 c.207G>T synonymous_variant 0.13
gyrB 5472 p.Ala78Asp missense_variant 0.12
gyrB 7155 p.Asp639Gly missense_variant 0.12
gyrB 7172 p.Asp645Tyr missense_variant 0.13
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491472 c.690A>G synonymous_variant 0.12
ccsA 620595 p.Phe235Leu missense_variant 0.13
rpoB 760471 p.Arg222His missense_variant 0.13
rpoB 760861 p.Pro352Leu missense_variant 0.18
rpoB 761030 c.1224G>C synonymous_variant 0.18
rpoB 761037 c.1231T>C synonymous_variant 0.18
rpoB 761051 c.1245G>C synonymous_variant 0.2
rpoB 761054 c.1248G>C synonymous_variant 0.18
rpoB 761057 c.1251G>C synonymous_variant 0.18
rpoB 761060 c.1254C>G synonymous_variant 0.2
rpoB 761084 c.1278C>A synonymous_variant 0.21
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.28
rpoB 761096 c.1290G>C synonymous_variant 0.24
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.2
rpoB 761102 c.1296A>G synonymous_variant 0.25
rpoB 761132 c.1326G>C synonymous_variant 0.11
rpoB 761628 c.1823delA frameshift_variant 0.13
rpoB 762200 c.2394C>T synonymous_variant 0.12
rpoB 762221 c.2415G>A synonymous_variant 0.12
rpoB 762233 c.2427G>C synonymous_variant 0.19
rpoB 762234 p.Pro810Ser missense_variant 0.13
rpoB 762239 c.2433G>A synonymous_variant 0.14
rpoB 762245 c.2439G>C synonymous_variant 0.14
rpoB 762248 c.2442G>A synonymous_variant 0.14
rpoB 762254 c.2448T>C synonymous_variant 0.13
rpoB 762257 c.2451C>T synonymous_variant 0.14
rpoB 762281 c.2475G>A synonymous_variant 0.17
rpoC 762458 c.-912C>T upstream_gene_variant 0.12
rpoC 763031 c.-339T>C upstream_gene_variant 0.1
rpoB 763038 p.Thr1078Ala missense_variant 0.11
rpoC 763043 c.-327G>C upstream_gene_variant 0.13
rpoC 763053 c.-317T>C upstream_gene_variant 0.16
rpoC 763070 c.-300T>C upstream_gene_variant 0.17
rpoB 763077 p.Val1091Thr missense_variant 0.17
rpoC 763082 c.-288C>T upstream_gene_variant 0.14
rpoC 763103 c.-267G>C upstream_gene_variant 0.18
rpoC 763699 c.330G>T synonymous_variant 0.14
rpoC 763714 c.345G>C synonymous_variant 0.16
rpoC 763717 c.348T>C synonymous_variant 0.17
rpoC 763718 p.Leu117Val missense_variant 0.16
rpoC 763729 c.360G>C synonymous_variant 0.17
rpoC 763751 p.Ile128Val missense_variant 0.14
rpoC 764437 p.Arg356Ser missense_variant 0.15
rpoC 764441 p.Ile358Leu missense_variant 0.15
rpoC 764446 p.Asp359Glu missense_variant 0.12
rpoC 764455 c.1086G>C synonymous_variant 0.12
rpoC 764458 c.1089G>C synonymous_variant 0.11
rpoC 764461 c.1092A>G synonymous_variant 0.16
rpoC 764485 c.1116G>C synonymous_variant 0.2
rpoC 764491 c.1122G>T synonymous_variant 0.14
rpoC 764503 c.1134G>T synonymous_variant 0.14
rpoC 764509 c.1140G>C synonymous_variant 0.14
rpoC 764512 c.1143G>C synonymous_variant 0.17
rpoC 764536 c.1167G>C synonymous_variant 0.23
rpoC 764543 p.Thr392Ala missense_variant 0.25
rpoC 764548 c.1179G>C synonymous_variant 0.27
rpoC 764551 c.1182G>C synonymous_variant 0.18
rpoC 764573 p.Leu402Ile missense_variant 0.22
rpoC 764578 c.1209C>G synonymous_variant 0.25
rpoC 764581 c.1212T>C synonymous_variant 0.25
rpoC 764582 p.Leu405Met missense_variant 0.29
rpoC 764593 c.1224C>T synonymous_variant 0.14
rpoC 764602 c.1233C>T synonymous_variant 0.33
rpoC 764605 c.1236G>T synonymous_variant 0.36
rpoC 764611 c.1242G>T synonymous_variant 0.31
rpoC 764623 c.1254C>G synonymous_variant 0.12
rpoC 764626 c.1257C>T synonymous_variant 0.27
rpoC 764632 c.1263T>C synonymous_variant 0.17
rpoC 764635 c.1266C>G synonymous_variant 0.21
rpoC 764644 c.1275G>T synonymous_variant 0.23
rpoC 764647 c.1278C>T synonymous_variant 0.16
rpoC 764650 c.1281G>T synonymous_variant 0.42
rpoC 764653 c.1284G>C synonymous_variant 0.18
rpoC 764656 c.1287C>A synonymous_variant 0.33
rpoC 764662 c.1293G>C synonymous_variant 0.46
rpoC 764664 p.Val432Gly missense_variant 0.26
rpoC 764671 c.1302G>C synonymous_variant 0.26
rpoC 764677 c.1308C>G synonymous_variant 0.15
rpoC 764678 p.Lys437Gln missense_variant 0.15
rpoC 764692 c.1323C>T synonymous_variant 0.28
rpoC 764701 c.1332C>T synonymous_variant 0.13
rpoC 764703 p.Lys445Ser missense_variant 0.12
rpoC 764706 p.Leu446Gln missense_variant 0.27
rpoC 764713 c.1344G>C synonymous_variant 0.24
rpoC 764731 c.1362G>T synonymous_variant 0.13
rpoC 766723 c.3354G>A synonymous_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776432 c.2049G>T synonymous_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781796 p.Met79Ile missense_variant 0.15
rpsL 781802 c.243G>C synonymous_variant 0.13
rpsL 781811 c.252C>T synonymous_variant 0.13
rpsL 781814 c.255C>T synonymous_variant 0.13
rpsL 781817 c.258G>T synonymous_variant 0.12
rpsL 781835 c.276T>C synonymous_variant 0.12
embR 1417091 p.Ala86Val missense_variant 0.17
atpE 1461256 c.214delG frameshift_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.4
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.81
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.86
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.89
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.19
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.87
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.87
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.87
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.96
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.95
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.42
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.88
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.49
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.14
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.37
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.98
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.46
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.85
rrs 1472274 n.429A>G non_coding_transcript_exon_variant 0.15
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.83
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.67
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.75
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.5
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.71
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.22
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.55
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.55
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.63
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.7
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.26
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.13
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.65
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.13
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.7
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.59
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.27
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.93
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.97
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.27
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.66
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.66
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.36
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.13
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.78
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.67
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.5
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.5
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.5
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.5
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.5
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.5
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.5
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.17
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.23
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.28
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.39
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.58
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.4
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.44
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.45
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.42
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.59
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.42
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.46
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.96
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.39
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.43
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.93
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.93
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.38
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.94
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.4
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.51
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.96
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.49
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.51
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.99
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.44
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.48
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.99
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.97
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.99
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.98
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.36
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.71
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.98
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.89
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.89
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.71
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.9
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.9
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.9
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.42
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.68
rrs 1473122 n.1281delA non_coding_transcript_exon_variant 0.64
rrs 1473122 n.1278A>T non_coding_transcript_exon_variant 0.83
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.31
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.46
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.96
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.36
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.35
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.99
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.93
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.93
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.91
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 1.0
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 1.0
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 1.0
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.86
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 1.0
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 1.0
rrl 1473384 n.-274A>G upstream_gene_variant 0.5
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.4
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.5
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.62
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.62
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.5
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.38
rrl 1474201 n.545delT non_coding_transcript_exon_variant 0.71
rrl 1474201 n.545T>A non_coding_transcript_exon_variant 0.75
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.11
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.2
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.95
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.3
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.2
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.22
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.22
rrl 1474275 n.618T>C non_coding_transcript_exon_variant 1.0
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 1.0
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 1.0
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 1.0
rrl 1474326 n.669T>A non_coding_transcript_exon_variant 1.0
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.83
rrl 1474381 n.724T>G non_coding_transcript_exon_variant 0.8
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.8
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.8
rrl 1474405 n.749delT non_coding_transcript_exon_variant 0.67
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.6
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.75
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.8
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.8
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.86
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.86
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.86
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.91
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.91
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.91
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 1.0
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 1.0
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.98
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.98
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 1.0
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 1.0
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 1.0
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 1.0
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.96
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.95
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.92
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.93
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.95
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.96
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.96
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.92
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 1.0
rrl 1475059 n.1403_1404insTA non_coding_transcript_exon_variant 1.0
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 1.0
rrl 1475065 n.1409_1411delCAA non_coding_transcript_exon_variant 1.0
rrl 1475080 n.1425_1426delCC non_coding_transcript_exon_variant 1.0
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 1.0
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475109 n.1452C>T non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475137 n.1480A>T non_coding_transcript_exon_variant 1.0
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 1.0
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 1.0
rrl 1475188 n.1531C>G non_coding_transcript_exon_variant 1.0
rrl 1475499 n.1842C>T non_coding_transcript_exon_variant 1.0
rrl 1475518 n.1861A>G non_coding_transcript_exon_variant 0.91
rrl 1475521 n.1864T>C non_coding_transcript_exon_variant 0.91
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 0.91
rrl 1475529 n.1872A>G non_coding_transcript_exon_variant 0.91
rrl 1475532 n.1875A>T non_coding_transcript_exon_variant 0.91
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.91
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.91
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.91
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.57
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.33
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.4
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.4
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 1.0
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 1.0
rrl 1475715 n.2058G>T non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.67
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.13
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.11
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.97
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.97
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.17
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.95
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.3
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.57
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.57
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.5
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.5
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.5
rrl 1476113 n.2456T>G non_coding_transcript_exon_variant 0.83
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.92
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.95
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.95
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.96
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.96
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.96
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.92
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.86
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.86
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.68
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.25
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.31
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.27
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.46
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.53
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.53
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.35
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.35
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.53
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.88
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.35
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.17
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.18
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.73
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.2
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.49
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.92
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.91
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.41
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.37
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.93
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.27
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.89
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.79
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.75
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.73
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.76
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.64
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.71
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.71
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.71
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.29
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.12
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.62
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.62
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.22
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.25
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.12
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.31
rrl 1476605 n.2948C>T non_coding_transcript_exon_variant 0.13
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.4
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.53
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.53
rrl 1476616 n.2959A>T non_coding_transcript_exon_variant 0.14
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.5
rrl 1476624 n.2967T>C non_coding_transcript_exon_variant 0.12
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.38
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.33
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.29
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.18
rpsA 1833676 c.135A>G synonymous_variant 0.17
rpsA 1833679 c.138G>C synonymous_variant 0.15
rpsA 1833684 p.Arg48His missense_variant 0.14
rpsA 1833694 c.153G>C synonymous_variant 0.31
rpsA 1833700 c.159C>T synonymous_variant 0.19
rpsA 1833721 c.180A>G synonymous_variant 0.31
rpsA 1833727 c.186G>C synonymous_variant 0.19
rpsA 1833732 p.Pro64Leu missense_variant 0.24
rpsA 1833734 p.Ala65Ser missense_variant 0.24
rpsA 1833742 c.201A>G synonymous_variant 0.23
rpsA 1834195 c.654G>C synonymous_variant 0.26
rpsA 1834231 c.690T>C synonymous_variant 0.12
rpsA 1834234 c.693G>C synonymous_variant 0.27
rpsA 1834240 c.699T>C synonymous_variant 0.28
rpsA 1834246 c.705G>T synonymous_variant 0.25
rpsA 1834249 c.708T>C synonymous_variant 0.47
rpsA 1834261 c.720A>G synonymous_variant 0.43
rpsA 1834264 c.723G>C synonymous_variant 0.42
rpsA 1834294 c.753G>C synonymous_variant 0.23
rpsA 1834298 p.Gln253Glu missense_variant 0.3
rpsA 1834306 c.765T>C synonymous_variant 0.22
rpsA 1834307 p.Asp256Gln missense_variant 0.22
rpsA 1834312 c.771G>A synonymous_variant 0.21
rpsA 1834327 c.786G>T synonymous_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102808 p.Gln79* stop_gained 0.11
ndh 2103071 c.-29C>T upstream_gene_variant 0.12
katG 2155285 p.His276Arg missense_variant 0.29
katG 2155488 p.Glu208Asp missense_variant 0.1
PPE35 2168089 p.Pro842Thr missense_variant 0.11
PPE35 2170066 p.Ala183Thr missense_variant 0.14
Rv1979c 2222743 p.Phe141Ser missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714305 p.Thr343Ser missense_variant 0.12
folC 2746761 p.Gln280* stop_gained 0.13
folC 2747386 c.212delG frameshift_variant 0.12
Rv2752c 3064598 p.Gly532Trp missense_variant 0.12
Rv2752c 3066027 c.165C>T synonymous_variant 1.0
Rv3236c 3612158 c.958delC frameshift_variant 0.14
fbiA 3640616 p.Leu25Pro missense_variant 0.1
fbiA 3641124 p.Ser194Arg missense_variant 0.11
alr 3840764 c.657G>C synonymous_variant 1.0
rpoA 3878182 p.Asp109Gly missense_variant 0.15
clpC1 4039994 p.Glu237Asp missense_variant 0.14
clpC1 4040009 c.696C>G synonymous_variant 0.11
clpC1 4040015 c.690G>C synonymous_variant 0.11
clpC1 4040018 c.687G>C synonymous_variant 0.11
clpC1 4040021 c.684A>C synonymous_variant 0.11
clpC1 4040024 c.681A>G synonymous_variant 0.11
clpC1 4040042 c.663C>T synonymous_variant 0.15
clpC1 4040066 c.639G>C synonymous_variant 0.18
embC 4240279 c.417G>A synonymous_variant 0.14
embA 4242310 c.-923C>T upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268647 p.Thr64Ala missense_variant 0.2
ethR 4326901 c.-648C>T upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0