TB-Profiler result

Run: SRR7755688

Summary

Run ID: SRR7755688

Sample name:

Date: 04-04-2023 20:15:05

Number of reads: 740399

Percentage reads mapped: 68.49

Strain: lineage4.2.1

Drug-resistance: Pre-XDR-TB


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 0.99
lineage4.2.1 Euro-American (TUR) H3;H4 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7570 p.Ala90Val missense_variant 1.0 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781822 p.Lys88Arg missense_variant 1.0 streptomycin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.48 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.55 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.52 kanamycin, capreomycin, aminoglycosides, amikacin
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
pncA 2288820 p.Gln141Pro missense_variant 1.0 pyrazinamide
eis 2715344 c.-12C>T upstream_gene_variant 1.0 kanamycin
embA 4243217 c.-16C>T upstream_gene_variant 1.0 ethambutol
embB 4247402 p.Ser297Ala missense_variant 0.95 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9677 c.2376C>T synonymous_variant 0.12
fgd1 491247 c.465C>T synonymous_variant 0.96
ccsA 619969 p.Val27Ile missense_variant 1.0
rpoB 761534 c.1728G>C synonymous_variant 0.15
rpoB 761537 c.1731C>G synonymous_variant 0.15
rpoB 761558 c.1752C>G synonymous_variant 0.22
rpoB 761564 c.1758G>T synonymous_variant 0.21
rpoB 761565 p.Met587Leu missense_variant 0.2
rpoB 761570 c.1764T>C synonymous_variant 0.18
rpoB 761573 c.1767C>G synonymous_variant 0.19
rpoB 761575 p.Phe590Tyr missense_variant 0.18
rpoB 761579 c.1773G>C synonymous_variant 0.19
rpoB 761600 c.1794T>C synonymous_variant 0.21
rpoB 761603 c.1797C>G synonymous_variant 0.21
rpoB 761612 c.1806G>C synonymous_variant 0.2
rpoB 761615 c.1809A>C synonymous_variant 0.21
rpoB 762233 c.2427G>T synonymous_variant 0.12
rpoB 762245 c.2439G>C synonymous_variant 0.12
rpoB 762254 c.2448T>C synonymous_variant 0.14
rpoB 762257 c.2451C>G synonymous_variant 0.15
rpoB 762266 c.2460T>C synonymous_variant 0.27
rpoB 762273 p.Ala823Ser missense_variant 0.27
rpoB 762284 c.2478G>C synonymous_variant 0.33
rpoB 762293 c.2487T>C synonymous_variant 0.2
rpoB 762296 c.2490G>C synonymous_variant 0.2
rpoB 762849 p.Tyr1015Asp missense_variant 0.2
rpoB 762855 p.Val1017Ile missense_variant 0.19
rpoB 762858 p.Thr1018Ser missense_variant 0.19
rpoC 762863 c.-507T>C upstream_gene_variant 0.19
rpoB 762870 p.Met1022Gln missense_variant 0.15
rpoB 762879 p.Met1025Leu missense_variant 0.12
rpoC 762923 c.-447C>G upstream_gene_variant 0.26
rpoC 762929 c.-441G>T upstream_gene_variant 0.26
rpoC 762947 c.-423C>G upstream_gene_variant 0.19
rpoC 762956 c.-414G>C upstream_gene_variant 0.14
rpoC 762971 c.-399G>C upstream_gene_variant 0.14
rpoC 762980 c.-390T>C upstream_gene_variant 0.17
rpoC 763486 c.117T>C synonymous_variant 0.14
rpoC 763504 c.135C>G synonymous_variant 0.17
rpoC 763507 c.138G>C synonymous_variant 0.18
rpoC 763528 c.159G>C synonymous_variant 0.21
rpoC 763531 c.162G>C synonymous_variant 0.19
rpoC 763534 c.165T>C synonymous_variant 0.2
rpoC 763540 c.171C>T synonymous_variant 0.28
rpoC 763546 c.177A>G synonymous_variant 0.22
rpoC 763551 p.Tyr61Ser missense_variant 0.25
rpoC 763570 c.201G>C synonymous_variant 0.25
rpoC 763578 p.Phe70Tyr missense_variant 0.25
rpoC 763621 c.252C>T synonymous_variant 0.24
rpoC 763633 c.264T>C synonymous_variant 0.26
rpoC 763636 c.267T>C synonymous_variant 0.27
rpoC 763642 c.273G>C synonymous_variant 0.26
rpoC 763648 c.279C>G synonymous_variant 0.27
rpoC 763652 p.Ile95Leu missense_variant 0.23
rpoC 763660 c.291T>C synonymous_variant 0.29
rpoC 763666 c.297G>T synonymous_variant 0.32
rpoC 763669 c.300C>G synonymous_variant 0.32
rpoC 763672 c.303C>G synonymous_variant 0.32
rpoC 763696 c.327T>C synonymous_variant 0.32
rpoC 763705 c.336G>T synonymous_variant 0.24
rpoC 763708 c.339G>T synonymous_variant 0.27
rpoC 763714 c.345G>C synonymous_variant 0.24
rpoC 763717 c.348T>C synonymous_variant 0.26
rpoC 763732 c.363C>G synonymous_variant 0.25
rpoC 763735 c.366G>C synonymous_variant 0.25
rpoC 763751 p.Ile128Val missense_variant 0.21
rpoC 764507 p.Ala380Ser missense_variant 0.18
rpoC 764521 c.1152T>C synonymous_variant 0.33
rpoC 764527 c.1158C>T synonymous_variant 0.33
rpoC 764536 c.1167G>T synonymous_variant 0.5
rpoC 764545 c.1176C>G synonymous_variant 0.38
rpoC 764548 c.1179G>C synonymous_variant 0.44
rpoC 764560 c.1191T>C synonymous_variant 0.44
rpoC 764561 p.Pro398Ala missense_variant 0.44
rpoC 764575 c.1206T>G synonymous_variant 0.38
rpoC 764578 c.1209C>G synonymous_variant 0.38
rpoC 764581 c.1212T>C synonymous_variant 0.38
rpoC 764582 p.Leu405Met missense_variant 0.38
rpoC 764605 c.1236G>C synonymous_variant 0.28
rpoC 764611 c.1242G>C synonymous_variant 0.28
rpoC 764632 c.1263T>C synonymous_variant 0.39
rpoC 764635 c.1266C>G synonymous_variant 0.39
rpoC 764650 c.1281G>C synonymous_variant 0.3
rpoC 764673 c.1305_1306insTTG conservative_inframe_insertion 0.29
rpoC 764676 p.Leu436Arg missense_variant 0.29
rpoC 764678 c.1310_1312delAGC disruptive_inframe_deletion 0.29
rpoC 764706 p.Leu446Gln missense_variant 0.38
rpoC 764713 c.1344G>A synonymous_variant 0.36
rpoC 764716 c.1347G>C synonymous_variant 0.36
rpoC 764817 p.Val483Gly missense_variant 1.0
rpoC 765962 c.2593T>C synonymous_variant 0.1
rpoC 765973 c.2604C>G synonymous_variant 0.11
rpoC 765974 p.Asp869Asn missense_variant 0.11
rpoC 765994 c.2625A>T synonymous_variant 0.13
rpoC 766000 c.2631G>C synonymous_variant 0.14
rpoC 766667 p.Ser1100Pro missense_variant 0.18
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303119 c.189G>A synonymous_variant 0.15
fbiC 1303158 c.228C>T synonymous_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.23
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.24
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.24
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.22
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.22
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.48
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.54
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.48
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.49
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.15
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.14
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.2
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.2
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.17
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.12
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.38
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.4
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.43
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.72
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.69
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.22
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.68
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.66
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.64
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.34
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.33
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.38
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.59
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.2
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.18
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.18
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.44
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.57
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.58
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.59
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.67
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.65
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.64
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.64
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.49
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.47
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.53
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.41
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.4
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.4
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.4
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.37
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.38
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.38
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.4
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.39
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.45
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.46
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.45
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.48
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.57
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.52
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.55
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.48
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.54
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.53
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.54
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.53
rrl 1473698 n.41G>A non_coding_transcript_exon_variant 0.3
rrl 1473699 n.42A>G non_coding_transcript_exon_variant 0.35
rrl 1473719 n.62G>C non_coding_transcript_exon_variant 0.37
rrl 1473721 n.64G>A non_coding_transcript_exon_variant 0.35
rrl 1473722 n.65G>T non_coding_transcript_exon_variant 0.35
rrl 1473744 n.87T>C non_coding_transcript_exon_variant 0.21
rrl 1473746 n.89T>A non_coding_transcript_exon_variant 0.21
rrl 1473747 n.90C>T non_coding_transcript_exon_variant 0.21
rrl 1473750 n.93C>G non_coding_transcript_exon_variant 0.21
rrl 1473753 n.96A>G non_coding_transcript_exon_variant 0.21
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.21
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 0.21
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.21
rrl 1473823 n.166T>C non_coding_transcript_exon_variant 0.18
rrl 1473833 n.176G>A non_coding_transcript_exon_variant 0.32
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.36
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.45
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.45
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.48
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.47
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.47
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.47
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.59
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.41
rrl 1473924 n.267A>T non_coding_transcript_exon_variant 0.35
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.22
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.24
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.24
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.24
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.24
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.21
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.21
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.23
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.26
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.35
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.23
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.24
rrl 1474284 n.631_633delCCT non_coding_transcript_exon_variant 0.2
rrl 1474293 n.637_651delCCTCTCCGGAGGAGG non_coding_transcript_exon_variant 0.26
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.21
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.35
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.37
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.33
rrl 1474353 n.696A>T non_coding_transcript_exon_variant 0.33
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.29
rrl 1474384 n.727C>T non_coding_transcript_exon_variant 0.24
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.25
rrl 1474450 n.793T>A non_coding_transcript_exon_variant 0.11
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.29
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.47
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.6
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.59
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.58
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.58
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.53
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.53
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.51
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.5
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.52
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.38
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.21
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.21
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.21
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.21
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.19
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.19
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.17
rrl 1474641 n.984G>A non_coding_transcript_exon_variant 0.19
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.17
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.15
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 0.15
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.15
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.15
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.17
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.18
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.24
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.24
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.25
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.43
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.45
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.5
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.51
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.58
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.57
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.58
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.58
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.66
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.57
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.58
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.47
rrl 1474945 n.1288C>T non_coding_transcript_exon_variant 0.16
rrl 1475515 n.1858G>A non_coding_transcript_exon_variant 0.32
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.35
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.33
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.36
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.34
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.33
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.34
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.14
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.19
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.21
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.21
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.25
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 0.33
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 0.33
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.47
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.74
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.61
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.37
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.69
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.64
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.64
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.64
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.64
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.62
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.67
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.63
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.62
rrl 1475963 n.2306G>A non_coding_transcript_exon_variant 0.61
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.55
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.53
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.52
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.52
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.54
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.47
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.47
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.19
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.19
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.5
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.5
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.63
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.64
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.62
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.57
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.6
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.55
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.55
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.39
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.37
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.3
rrl 1476255 n.2598A>G non_coding_transcript_exon_variant 0.3
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.3
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.29
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.31
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.24
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.32
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.47
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.5
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.55
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.57
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.54
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.46
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.44
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.43
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.43
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.38
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.4
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.42
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.42
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.38
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.38
inhA 1674273 p.His24Gln missense_variant 0.11
rpsA 1833646 c.105T>C synonymous_variant 0.13
rpsA 1833653 p.Ile38Leu missense_variant 0.12
rpsA 1833658 c.117C>G synonymous_variant 0.11
rpsA 1833668 p.Ile43Val missense_variant 0.11
rpsA 1833676 c.135A>G synonymous_variant 0.12
rpsA 1833679 c.138G>C synonymous_variant 0.14
rpsA 1833682 c.141C>T synonymous_variant 0.2
rpsA 1833685 c.144G>T synonymous_variant 0.21
rpsA 1833694 c.153G>C synonymous_variant 0.2
rpsA 1833721 c.180A>G synonymous_variant 0.17
rpsA 1834069 c.528G>C synonymous_variant 0.13
rpsA 1834090 c.549G>C synonymous_variant 0.14
rpsA 1834096 c.555G>C synonymous_variant 0.14
rpsA 1834099 c.558C>G synonymous_variant 0.11
rpsA 1834105 c.564C>T synonymous_variant 0.11
rpsA 1834108 c.567C>G synonymous_variant 0.11
rpsA 1834114 c.573G>C synonymous_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155373 p.Asp247Asn missense_variant 0.12
PPE35 2169879 p.Phe245Cys missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518522 p.Lys136Asn missense_variant 0.2
ribD 2987468 c.630G>A synonymous_variant 0.13
Rv2752c 3065893 p.Ile100Asn missense_variant 0.17
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086933 c.115delG frameshift_variant 0.57
ald 3087255 c.437dupC frameshift_variant 0.43
ald 3087925 p.Val369Gly missense_variant 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474215 p.Thr70Met missense_variant 0.18
fprA 3474427 p.Val141Leu missense_variant 0.12
clpC1 4038512 c.2193C>T synonymous_variant 0.22
clpC1 4038857 c.1848C>A synonymous_variant 0.2
clpC1 4039714 p.Tyr331His missense_variant 0.17
clpC1 4039724 c.981A>G synonymous_variant 0.16
clpC1 4039727 c.978C>T synonymous_variant 0.17
clpC1 4039730 c.975C>G synonymous_variant 0.17
clpC1 4039748 c.957G>C synonymous_variant 0.18
clpC1 4039751 c.954A>G synonymous_variant 0.18
clpC1 4039757 c.948A>G synonymous_variant 0.18
clpC1 4039760 c.945T>C synonymous_variant 0.17
clpC1 4039766 c.939T>C synonymous_variant 0.17
clpC1 4039769 c.936C>G synonymous_variant 0.18
clpC1 4039773 p.Lys311Met missense_variant 0.18
clpC1 4039775 c.930G>C synonymous_variant 0.18
clpC1 4039778 c.927A>G synonymous_variant 0.18
clpC1 4039781 c.924G>C synonymous_variant 0.17
clpC1 4039967 p.Gln246His missense_variant 0.2
clpC1 4039988 c.717C>G synonymous_variant 0.25
clpC1 4039991 c.714G>C synonymous_variant 0.29
clpC1 4039994 p.Glu237Asp missense_variant 0.29
clpC1 4040001 p.His235Arg missense_variant 0.31
clpC1 4040015 c.690G>C synonymous_variant 0.38
clpC1 4040021 c.684A>C synonymous_variant 0.4
clpC1 4040024 c.681A>G synonymous_variant 0.29
clpC1 4040030 c.675C>G synonymous_variant 0.21
clpC1 4040033 c.672G>C synonymous_variant 0.21
clpC1 4040045 c.660C>G synonymous_variant 0.11
clpC1 4040051 c.654C>G synonymous_variant 0.22
clpC1 4040069 c.636G>C synonymous_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249594 c.3081G>A synonymous_variant 0.91
ethA 4326632 p.His281Pro missense_variant 1.0
ethA 4328376 c.-903G>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0