TB-Profiler result

Run: ERR3439489
Summary

Run ID: ERR3439489

Sample name:

Date: 01-04-2023 02:09:15

Number of reads: 807185

Percentage reads mapped: 44.61

Strain: La1.8.1

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La1 M.bovis None None 1.0
La1.8 M.bovis None None 1.0
La1.8.1 M.bovis None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.26 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.87 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.6 kanamycin, capreomycin, aminoglycosides, amikacin
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5390 p.Asp51Asn missense_variant 0.13
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 8741 c.1440C>T synonymous_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9217 p.Asp639Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 760713 p.Ala303Thr missense_variant 0.15
rpoB 761015 c.1209G>C synonymous_variant 0.19
rpoB 761027 c.1221A>C synonymous_variant 0.23
rpoB 761036 c.1230G>C synonymous_variant 0.22
rpoB 761037 c.1231T>C synonymous_variant 0.22
rpoB 761046 p.Ile414Val missense_variant 0.2
rpoB 761051 c.1245G>A synonymous_variant 0.19
rpoB 761054 c.1248G>C synonymous_variant 0.19
rpoB 761057 c.1251G>C synonymous_variant 0.2
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 0.2
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.19
rpoB 761102 c.1296A>G synonymous_variant 0.2
rpoB 761132 c.1326G>C synonymous_variant 0.28
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.28
rpoB 761150 c.1344A>C synonymous_variant 0.28
rpoB 761153 c.1347G>C synonymous_variant 0.29
rpoB 761162 c.1356G>C synonymous_variant 0.26
rpoB 761165 c.1359G>C synonymous_variant 0.16
rpoB 761174 c.1368T>C synonymous_variant 0.12
rpoB 761177 c.1371G>C synonymous_variant 0.12
rpoB 761183 c.1377T>C synonymous_variant 0.12
rpoB 761186 p.Glu460Asp missense_variant 0.12
rpoB 761192 c.1386C>G synonymous_variant 0.13
rpoB 761195 c.1389G>C synonymous_variant 0.13
rpoB 761196 p.Leu464Val missense_variant 0.12
rpoB 761234 c.1428G>C synonymous_variant 0.12
rpoB 761255 c.1449T>G synonymous_variant 0.12
rpoB 762053 c.2247T>C synonymous_variant 0.14
rpoB 762057 p.Ile751Val missense_variant 0.14
rpoB 762062 c.2256T>C synonymous_variant 0.15
rpoB 762065 c.2259T>C synonymous_variant 0.16
rpoB 762080 c.2274G>C synonymous_variant 0.16
rpoB 762083 c.2277T>C synonymous_variant 0.16
rpoB 762084 p.Ala760Lys missense_variant 0.16
rpoB 762105 p.Ile767Leu missense_variant 0.15
rpoC 762854 c.-516G>C upstream_gene_variant 0.2
rpoC 762857 c.-513C>G upstream_gene_variant 0.2
rpoB 762858 p.Thr1018Ser missense_variant 0.2
rpoC 762863 c.-507T>C upstream_gene_variant 0.22
rpoB 762879 p.Met1025Leu missense_variant 0.27
rpoC 762896 c.-474G>C upstream_gene_variant 0.26
rpoC 762929 c.-441G>C upstream_gene_variant 0.26
rpoC 762932 c.-438G>C upstream_gene_variant 0.27
rpoC 762947 c.-423C>G upstream_gene_variant 0.32
rpoC 762962 c.-408C>T upstream_gene_variant 0.31
rpoC 762980 c.-390T>C upstream_gene_variant 0.28
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763468 c.99G>C synonymous_variant 0.14
rpoC 763486 c.117T>G synonymous_variant 0.13
rpoC 763492 c.123G>C synonymous_variant 0.12
rpoC 763504 c.135C>G synonymous_variant 0.12
rpoC 763507 c.138G>C synonymous_variant 0.12
rpoC 763511 p.Cys48Gly missense_variant 0.12
rpoC 763534 c.165T>C synonymous_variant 0.12
rpoC 763546 c.177A>G synonymous_variant 0.14
rpoC 763550 p.Tyr61Ala missense_variant 0.14
rpoC 763570 c.201G>C synonymous_variant 0.17
rpoC 763573 c.204G>C synonymous_variant 0.17
rpoC 763589 p.Ile74Val missense_variant 0.15
rpoC 763600 c.231C>G synonymous_variant 0.12
rpoC 763606 c.237C>G synonymous_variant 0.12
rpoC 764611 c.1242G>C synonymous_variant 0.12
rpoC 764632 c.1263T>C synonymous_variant 0.18
rpoC 764650 c.1281G>T synonymous_variant 0.35
rpoC 764662 c.1293G>C synonymous_variant 0.39
rpoC 764677 c.1308C>G synonymous_variant 0.4
rpoC 764706 p.Leu446Gln missense_variant 0.43
rpoC 764722 c.1353G>C synonymous_variant 0.41
rpoC 764740 p.Met457Ile missense_variant 0.36
rpoC 764746 c.1377G>C synonymous_variant 0.36
rpoC 764749 c.1380G>C synonymous_variant 0.35
rpoC 764750 p.Val461Ile missense_variant 0.35
rpoC 764758 c.1389C>G synonymous_variant 0.32
rpoC 764760 p.Asn464Ser missense_variant 0.32
rpoC 764764 c.1395T>C synonymous_variant 0.32
rpoC 764780 p.Ser471Ala missense_variant 0.29
rpoC 764797 c.1428G>C synonymous_variant 0.2
rpoC 766310 p.Arg981Cys missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781682 c.123T>C synonymous_variant 0.16
rpsL 781685 c.126G>C synonymous_variant 0.16
rpsL 781706 c.147T>C synonymous_variant 0.16
rpsL 781709 c.150G>C synonymous_variant 0.16
rpsL 781715 c.156T>C synonymous_variant 0.17
rpsL 781721 c.162C>T synonymous_variant 0.16
rpsL 781728 c.169_171delTTGinsCTC synonymous_variant 0.15
rpsL 781731 p.Thr58Ser missense_variant 0.15
rpsL 781751 c.192G>C synonymous_variant 0.21
rpsL 781754 c.195G>C synonymous_variant 0.22
rpsL 781760 c.201T>C synonymous_variant 0.21
rpsL 781802 c.243G>C synonymous_variant 0.38
rpsL 781817 c.258G>T synonymous_variant 0.37
rpsL 781829 c.270G>C synonymous_variant 0.35
rpsL 781832 c.273T>C synonymous_variant 0.35
rpsL 781835 c.276T>C synonymous_variant 0.36
rpsL 781859 c.300T>C synonymous_variant 0.32
rpsL 781860 p.Ser101Ala missense_variant 0.32
rpsL 781865 c.306G>C synonymous_variant 0.33
rpsL 781868 c.309T>C synonymous_variant 0.35
rpsL 781876 p.Gly106Ala missense_variant 0.36
rpsL 781880 c.321C>G synonymous_variant 0.38
rpsL 781892 c.333A>G synonymous_variant 0.39
rpsL 781898 c.339A>T synonymous_variant 0.38
rpsL 781901 c.342C>T synonymous_variant 0.32
rpsL 781907 c.348T>C synonymous_variant 0.33
rpsL 781916 c.357T>G synonymous_variant 0.24
rpsL 781921 p.Lys121Met missense_variant 0.24
rplC 800612 c.-197A>T upstream_gene_variant 0.25
rplC 800618 c.-191T>C upstream_gene_variant 0.25
rplC 800631 c.-178_-176delTATinsGTG upstream_gene_variant 0.25
rplC 800648 c.-161A>G upstream_gene_variant 0.4
rplC 800651 c.-158G>C upstream_gene_variant 0.4
rplC 800654 c.-155T>C upstream_gene_variant 0.43
rplC 800667 c.-142_-140delTCGinsAGC upstream_gene_variant 0.46
rplC 800672 c.-137G>C upstream_gene_variant 0.46
rplC 800693 c.-116A>C upstream_gene_variant 0.5
rplC 800702 c.-107G>T upstream_gene_variant 0.46
rplC 800703 c.-106T>G upstream_gene_variant 0.46
rplC 800715 c.-94_-92delATCinsGTG upstream_gene_variant 0.4
rplC 800720 c.-89T>C upstream_gene_variant 0.4
rplC 800723 c.-86C>G upstream_gene_variant 0.4
rplC 800729 c.-80G>C upstream_gene_variant 0.38
rplC 800733 c.-76A>G upstream_gene_variant 0.4
rplC 800738 c.-71T>C upstream_gene_variant 0.4
rplC 800742 c.-67G>T upstream_gene_variant 0.4
rplC 800753 c.-56C>T upstream_gene_variant 0.38
rplC 800754 c.-55A>C upstream_gene_variant 0.38
rplC 800762 c.-47T>C upstream_gene_variant 0.3
rplC 800767 c.-41_-36delCAGCGT upstream_gene_variant 0.33
rplC 800893 p.Val29Ile missense_variant 0.12
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
embR 1417369 c.-22C>A upstream_gene_variant 0.15
atpE 1460860 c.-185C>A upstream_gene_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.25
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.25
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.25
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.25
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.25
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.31
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.4
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.35
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.27
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.2
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.43
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.69
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.65
rrs 1472582 n.737G>C non_coding_transcript_exon_variant 0.69
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.72
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.75
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.7
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.7
rrs 1472666 n.821G>A non_coding_transcript_exon_variant 0.7
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.68
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.68
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.68
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.68
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.68
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.68
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.68
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.68
rrs 1472694 n.849C>T non_coding_transcript_exon_variant 0.65
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.68
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.68
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.2
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.46
rrs 1472956 n.1111T>G non_coding_transcript_exon_variant 0.46
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.46
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.46
rrs 1472990 n.1145A>T non_coding_transcript_exon_variant 0.46
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.74
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.74
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.74
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.81
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.85
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.85
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.85
rrs 1473109 n.1264T>C non_coding_transcript_exon_variant 0.85
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.85
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.85
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.86
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.86
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.83
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 0.83
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.77
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.77
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.64
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.69
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 0.69
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.69
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.64
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.64
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.3
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.27
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.38
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.38
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.38
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.43
rrl 1474284 n.629_640delCTCCTTTTCCTC non_coding_transcript_exon_variant 0.5
rrl 1474301 n.644G>C non_coding_transcript_exon_variant 0.6
rrl 1474303 n.646A>T non_coding_transcript_exon_variant 0.6
rrl 1474305 n.648G>T non_coding_transcript_exon_variant 0.6
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.5
rrl 1474308 n.653_654delTG non_coding_transcript_exon_variant 0.43
rrl 1474316 n.659T>C non_coding_transcript_exon_variant 0.43
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.33
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.33
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 0.33
rrl 1474355 n.698A>C non_coding_transcript_exon_variant 0.33
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 0.33
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.33
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.25
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.38
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.42
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.42
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.42
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.5
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.5
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.62
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.65
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.7
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.7
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.76
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.77
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.8
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.8
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.8
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.82
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.7
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.7
rrl 1474675 n.1018C>A non_coding_transcript_exon_variant 0.7
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.7
rrl 1474709 n.1053_1056delTGGT non_coding_transcript_exon_variant 0.73
rrl 1474717 n.1060_1061insGTGAG non_coding_transcript_exon_variant 0.73
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.64
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.64
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.69
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.72
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.72
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.72
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.77
rrl 1474770 n.1113G>A non_coding_transcript_exon_variant 0.78
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.79
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.79
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.81
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.8
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.76
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.77
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.8
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.79
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.78
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.47
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.38
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.33
rrl 1474920 n.1263G>A non_coding_transcript_exon_variant 0.33
rrl 1475696 n.2039T>A non_coding_transcript_exon_variant 0.73
rrl 1475703 n.2046A>T non_coding_transcript_exon_variant 0.77
rrl 1475747 n.2090A>C non_coding_transcript_exon_variant 0.79
rrl 1475750 n.2093A>C non_coding_transcript_exon_variant 0.21
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.79
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.79
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.79
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.79
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.79
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.79
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.71
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.79
rrl 1475767 n.2110G>A non_coding_transcript_exon_variant 0.79
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.8
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.8
rrl 1475781 n.2124T>G non_coding_transcript_exon_variant 0.81
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.8
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.8
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.8
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.8
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.8
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.8
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.77
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.7
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.68
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.68
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.58
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.56
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.5
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.42
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.33
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.33
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.38
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.29
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.29
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 0.29
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.29
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.29
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.38
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.56
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.56
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.56
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.8
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.8
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.69
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.75
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.8
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.8
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.75
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.69
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.69
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.69
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.69
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.69
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.69
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.75
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.75
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.8
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.84
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.88
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.8
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.85
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.86
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.85
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.85
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.85
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.85
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.85
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.85
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.85
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.85
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.85
rrl 1476540 n.2883C>T non_coding_transcript_exon_variant 0.92
rrl 1476544 n.2887T>A non_coding_transcript_exon_variant 1.0
rrl 1476566 n.2909A>T non_coding_transcript_exon_variant 0.92
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.92
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.89
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.88
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.86
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.83
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.8
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.5
rpsA 1834249 c.708T>C synonymous_variant 0.14
rpsA 1834261 c.720A>C synonymous_variant 0.18
rpsA 1834279 p.Asp246Glu missense_variant 0.2
rpsA 1834285 c.744G>C synonymous_variant 0.15
rpsA 1834286 c.745_746delTCinsAG synonymous_variant 0.15
rpsA 1834294 c.753G>C synonymous_variant 0.15
rpsA 1834298 p.Gln253Glu missense_variant 0.14
rpsA 1834303 c.762T>C synonymous_variant 0.14
rpsA 1834306 c.765T>C synonymous_variant 0.14
rpsA 1834307 p.Asp256Gln missense_variant 0.13
rpsA 1834331 p.Asp264Ser missense_variant 0.28
rpsA 1834339 p.Asp266Glu missense_variant 0.29
rpsA 1834340 p.Met267Leu missense_variant 0.29
rpsA 1834348 c.807T>C synonymous_variant 0.25
rpsA 1834354 c.813G>C synonymous_variant 0.24
rpsA 1834357 c.816T>C synonymous_variant 0.24
rpsA 1834361 c.820_822delTTGinsCTC synonymous_variant 0.24
rpsA 1834366 c.825A>G synonymous_variant 0.24
rpsA 1834378 c.837T>G synonymous_variant 0.24
rpsA 1834395 p.Arg285Gln missense_variant 0.2
rpsA 1834397 p.His286Val missense_variant 0.2
rpsA 1834411 c.870T>C synonymous_variant 0.24
rpsA 1834423 c.882G>T synonymous_variant 0.21
rpsA 1834427 p.Ile296Val missense_variant 0.21
rpsA 1834431 p.Val297Ala missense_variant 0.2
rpsA 1834447 c.906C>G synonymous_variant 0.2
rpsA 1834451 c.910T>C synonymous_variant 0.2
rpsA 1834859 p.Ala440Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102193 p.Arg284Trp missense_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156025 c.87C>A synonymous_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168011 p.Ser868Arg missense_variant 1.0
PPE35 2168319 p.Thr765Ile missense_variant 1.0
PPE35 2168647 p.Val656Met missense_variant 0.14
PPE35 2168814 c.1798dupA frameshift_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
eis 2715125 p.Thr70Ala missense_variant 1.0
Rv2752c 3065988 p.Glu68Asp missense_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474427 p.Val141Ile missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
rpoA 3878298 c.210A>G synonymous_variant 0.14
rpoA 3878304 c.204G>C synonymous_variant 0.15
rpoA 3878313 c.195G>C synonymous_variant 0.15
rpoA 3878316 p.Thr64Ser missense_variant 0.14
rpoA 3878322 c.186A>G synonymous_variant 0.14
rpoA 3878331 c.177A>G synonymous_variant 0.15
rpoA 3878334 c.174T>C synonymous_variant 0.15
rpoA 3878337 c.171T>C synonymous_variant 0.14
rpoA 3878346 c.162T>C synonymous_variant 0.14
rpoA 3878352 c.156C>G synonymous_variant 0.14
rpoA 3878364 c.144A>G synonymous_variant 0.15
rpoA 3878367 c.141C>G synonymous_variant 0.15
rpoA 3878370 c.138T>C synonymous_variant 0.15
rpoA 3878376 c.132G>C synonymous_variant 0.18
rpoA 3878379 c.129G>C synonymous_variant 0.17
rpoA 3878382 c.126G>C synonymous_variant 0.14
rpoA 3878394 c.114G>C synonymous_variant 0.14
rpoA 3878400 c.108T>C synonymous_variant 0.14
rpoA 3878415 c.93C>T synonymous_variant 0.14
rpoA 3878630 c.-124delC upstream_gene_variant 1.0
ddn 3986981 c.138C>T synonymous_variant 0.17
clpC1 4038403 c.2302T>C synonymous_variant 1.0
clpC1 4039898 c.807C>G synonymous_variant 0.14
clpC1 4039904 c.801A>G synonymous_variant 0.2
clpC1 4039916 c.789T>C synonymous_variant 0.2
clpC1 4039931 c.774T>C synonymous_variant 0.19
clpC1 4039937 p.Val256Ile missense_variant 0.21
clpC1 4039940 c.765G>C synonymous_variant 0.21
clpC1 4039946 c.759A>C synonymous_variant 0.21
clpC1 4039949 c.756G>C synonymous_variant 0.2
clpC1 4039952 c.753T>C synonymous_variant 0.2
clpC1 4039955 c.750G>C synonymous_variant 0.23
clpC1 4039960 p.Thr249Ser missense_variant 0.28
clpC1 4039979 c.726C>G synonymous_variant 0.37
clpC1 4040000 p.His235Lys missense_variant 0.44
clpC1 4040003 c.702G>C synonymous_variant 0.44
clpC1 4040009 c.696C>G synonymous_variant 0.44
clpC1 4040018 c.687G>C synonymous_variant 0.41
clpC1 4040021 c.684A>C synonymous_variant 0.4
clpC1 4040024 c.681A>G synonymous_variant 0.4
clpC1 4040033 c.672G>C synonymous_variant 0.41
clpC1 4040063 c.642G>C synonymous_variant 0.35
clpC1 4040066 c.639G>C synonymous_variant 0.36
clpC1 4040069 c.636G>C synonymous_variant 0.36
clpC1 4040083 p.Thr208Ser missense_variant 0.38
clpC1 4040087 c.618G>C synonymous_variant 0.38
clpC1 4040090 c.615T>C synonymous_variant 0.38
clpC1 4040096 p.Val203Ile missense_variant 0.38
clpC1 4040117 c.588A>G synonymous_variant 0.29
clpC1 4040129 c.576C>G synonymous_variant 0.23
clpC1 4040135 c.570C>G synonymous_variant 0.22
clpC1 4040330 c.375C>G synonymous_variant 0.12
clpC1 4040357 c.348T>C synonymous_variant 0.12
clpC1 4040363 c.342A>C synonymous_variant 0.14
clpC1 4040387 c.318A>G synonymous_variant 0.11
clpC1 4040393 c.312G>C synonymous_variant 0.11
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embC 4242981 p.Met1040Thr missense_variant 1.0
embA 4244183 c.951G>T synonymous_variant 0.15
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246406 c.-108G>A upstream_gene_variant 0.14
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4249626 p.Gly1038Glu missense_variant 0.12
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0