TB-Profiler result

Run: ERR8975532
Summary

Run ID: ERR8975532

Sample name:

Date: 02-04-2023 08:52:04

Number of reads: 2204251

Percentage reads mapped: 86.76

Strain: lineage4.3.2.1

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.99
lineage4.3.2 Euro-American (LAM) LAM3 None 0.98
lineage4.3.2.1 Euro-American (LAM) LAM3 RD761 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5520 p.Pro94Leu missense_variant 0.95
gyrA 7222 c.-80C>T upstream_gene_variant 0.95
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8174 c.873C>G synonymous_variant 0.15
gyrA 8177 c.876A>C synonymous_variant 0.15
gyrA 8189 c.888G>T synonymous_variant 0.16
gyrA 8217 p.Ser306Gly missense_variant 0.15
gyrA 8225 p.Asp308Glu missense_variant 0.18
gyrA 8235 p.Leu312Val missense_variant 0.16
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575713 c.366G>A synonymous_variant 0.16
mshA 575746 c.399C>G synonymous_variant 0.15
ccsA 620325 c.435G>T synonymous_variant 0.14
ccsA 620337 c.447C>G synonymous_variant 0.15
ccsA 620358 c.468C>G synonymous_variant 0.16
ccsA 620397 c.507C>G synonymous_variant 0.25
ccsA 620404 c.514C>T synonymous_variant 0.22
ccsA 620415 c.525T>C synonymous_variant 0.19
ccsA 620418 c.528G>C synonymous_variant 0.19
rpoB 760563 p.Arg253Met missense_variant 0.15
rpoB 760577 c.771G>A synonymous_variant 0.17
rpoB 760928 c.1122G>C synonymous_variant 0.15
rpoB 760946 c.1140A>G synonymous_variant 0.16
rpoB 760971 c.1165C>A synonymous_variant 0.15
rpoB 760994 c.1188G>A synonymous_variant 0.16
rpoB 761006 c.1200C>T synonymous_variant 0.17
rpoB 761015 c.1209G>C synonymous_variant 0.18
rpoB 761027 c.1221A>G synonymous_variant 0.16
rpoB 761036 c.1230G>A synonymous_variant 0.16
rpoB 761037 c.1231T>C synonymous_variant 0.16
rpoB 761051 c.1245G>C synonymous_variant 0.15
rpoB 761876 c.2070C>A synonymous_variant 0.15
rpoB 761891 c.2085G>C synonymous_variant 0.14
rpoC 762470 c.-900G>C upstream_gene_variant 0.17
rpoB 762490 p.Val895Asp missense_variant 0.15
rpoB 762510 p.Ala902Pro missense_variant 0.15
rpoC 762518 c.-852C>G upstream_gene_variant 0.15
rpoC 762929 c.-441G>C upstream_gene_variant 0.19
rpoC 762995 c.-375G>C upstream_gene_variant 0.19
rpoC 763028 c.-342T>C upstream_gene_variant 0.18
rpoC 763031 c.-339T>G upstream_gene_variant 0.18
rpoC 763034 c.-336C>G upstream_gene_variant 0.18
rpoC 763040 c.-330C>G upstream_gene_variant 0.16
rpoC 763050 c.-320C>T upstream_gene_variant 0.18
rpoC 763076 c.-294C>T upstream_gene_variant 0.15
rpoC 763468 c.99G>C synonymous_variant 0.17
rpoC 763486 c.117T>C synonymous_variant 0.17
rpoC 763505 c.136C>T synonymous_variant 0.23
rpoC 763561 c.192G>A synonymous_variant 0.2
rpoC 763600 c.231C>T synonymous_variant 0.18
rpoC 763606 c.237C>T synonymous_variant 0.19
rpoC 763618 c.249C>A synonymous_variant 0.18
rpoC 763633 c.264T>C synonymous_variant 0.15
rpoC 763636 c.267T>G synonymous_variant 0.16
rpoC 763639 c.270G>A synonymous_variant 0.16
rpoC 763660 c.291T>G synonymous_variant 0.15
rpoC 763666 c.297G>A synonymous_variant 0.16
rpoC 763696 c.327T>C synonymous_variant 0.17
rpoC 763699 c.330G>C synonymous_variant 0.16
rpoC 763702 c.333C>G synonymous_variant 0.17
rpoC 763708 c.339G>C synonymous_variant 0.17
rpoC 763714 c.345G>C synonymous_variant 0.19
rpoC 763717 c.348T>C synonymous_variant 0.19
rpoC 763732 c.363C>G synonymous_variant 0.17
rpoC 763735 c.366G>C synonymous_variant 0.18
rpoC 763744 c.375G>C synonymous_variant 0.18
rpoC 764576 p.Ser403Thr missense_variant 0.14
rpoC 764587 c.1218C>G synonymous_variant 0.16
rpoC 764648 c.1279C>A synonymous_variant 0.18
rpoC 764653 c.1284G>C synonymous_variant 0.17
rpoC 764656 c.1287C>T synonymous_variant 0.18
rpoC 764668 c.1299C>T synonymous_variant 0.18
rpoC 764674 c.1305G>A synonymous_variant 0.17
rpoC 764681 c.1312C>T synonymous_variant 0.16
rpoC 764995 c.1626C>G synonymous_variant 0.99
rpoC 765526 c.2157C>G synonymous_variant 0.15
rpoC 765541 c.2172C>A synonymous_variant 0.15
rpoC 765622 p.Glu751Asp missense_variant 0.16
rpoC 765628 c.2259G>C synonymous_variant 0.16
rpoC 765676 c.2307G>A synonymous_variant 0.19
rpoC 765688 c.2319G>C synonymous_variant 0.19
rpoC 765689 c.2320C>T synonymous_variant 0.18
rpoC 765694 c.2325G>C synonymous_variant 0.17
rpoC 765700 c.2331T>C synonymous_variant 0.17
rpoC 765724 c.2355C>G synonymous_variant 0.18
rpoC 765727 c.2358T>C synonymous_variant 0.17
rpoC 765734 c.2365T>C synonymous_variant 0.23
rpoC 765748 c.2379C>T synonymous_variant 0.21
rpoC 765752 p.Asp795Ser missense_variant 0.21
rpoC 765757 c.2388C>T synonymous_variant 0.21
rpoC 765796 c.2427C>T synonymous_variant 0.16
rpoC 765811 c.2442T>C synonymous_variant 0.15
rpoC 765814 c.2445A>G synonymous_variant 0.16
rpoC 765826 c.2457T>A synonymous_variant 0.14
rpoC 765850 c.2481G>C synonymous_variant 0.16
rpoC 766360 c.2991C>T synonymous_variant 0.16
rpoC 766381 c.3012C>T synonymous_variant 0.2
rpoC 766384 c.3015A>G synonymous_variant 0.2
rpoC 766387 c.3018C>G synonymous_variant 0.21
rpoC 766393 c.3024C>G synonymous_variant 0.2
rpoC 766397 c.3028C>T synonymous_variant 0.18
rpoC 766408 c.3039C>T synonymous_variant 0.19
rpoC 766417 c.3048C>T synonymous_variant 0.17
rpoC 766483 c.3114G>C synonymous_variant 0.18
rpoC 766486 c.3117A>G synonymous_variant 0.17
rpoC 766492 c.3123T>C synonymous_variant 0.15
rpoC 766495 c.3126C>T synonymous_variant 0.14
rpoC 766519 c.3150C>A synonymous_variant 0.15
rpoC 766570 c.3201T>G synonymous_variant 0.15
rpoC 766573 c.3204T>C synonymous_variant 0.16
rpoC 766583 p.Gly1072Ser missense_variant 0.15
rpoC 766594 c.3225G>C synonymous_variant 0.15
rpoC 766597 c.3228C>G synonymous_variant 0.14
rpoC 766864 c.3495G>C synonymous_variant 0.18
rpoC 766894 c.3525T>C synonymous_variant 0.16
rpoC 766895 c.3526T>C synonymous_variant 0.17
rpoC 766900 c.3531T>C synonymous_variant 0.17
rpoC 766903 c.3534C>T synonymous_variant 0.19
rpoC 766907 c.3538C>T synonymous_variant 0.19
rpoC 766918 c.3549C>T synonymous_variant 0.21
rpoC 766921 c.3552G>C synonymous_variant 0.21
rpoC 766933 c.3564A>G synonymous_variant 0.18
rpoC 766945 c.3576A>G synonymous_variant 0.17
rpoC 766972 c.3603G>C synonymous_variant 0.15
rpoC 766975 c.3606C>T synonymous_variant 0.16
rpoC 766996 c.3627C>T synonymous_variant 0.19
rpoC 767002 c.3633G>C synonymous_variant 0.19
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781880 c.321C>G synonymous_variant 0.15
rpsL 781898 c.339A>T synonymous_variant 0.15
rpsL 781916 c.357T>C synonymous_variant 0.19
rpsL 781929 p.Gly124Ser missense_variant 0.17
fbiC 1303632 c.702T>G synonymous_variant 0.14
fbiC 1303768 p.Ser280Ala missense_variant 0.14
atpE 1461161 c.117C>T synonymous_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471935 n.90T>C non_coding_transcript_exon_variant 0.14
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.23
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.23
rrs 1471984 n.139T>A non_coding_transcript_exon_variant 0.22
rrs 1471985 n.140T>C non_coding_transcript_exon_variant 0.22
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.2
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.2
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.2
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.2
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.19
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.21
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.22
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.21
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 0.89
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.18
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.18
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.17
rrl 1474034 n.377G>A non_coding_transcript_exon_variant 0.15
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.14
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.13
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.17
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.16
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.18
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.21
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.16
rrl 1474950 n.1293G>A non_coding_transcript_exon_variant 0.16
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.16
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 0.16
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.16
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.16
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 0.17
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 0.23
rrl 1475006 n.1349A>G non_coding_transcript_exon_variant 0.23
rrl 1475028 n.1371G>A non_coding_transcript_exon_variant 0.22
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.15
rrl 1475369 n.1712G>A non_coding_transcript_exon_variant 0.16
rrl 1476035 n.2378G>A non_coding_transcript_exon_variant 0.2
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.23
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.23
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.23
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.21
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.23
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.23
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.19
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.2
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.17
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.16
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.16
rpsA 1833718 c.177C>T synonymous_variant 0.14
rpsA 1833745 c.204G>C synonymous_variant 0.15
rpsA 1833802 c.261A>G synonymous_variant 0.15
rpsA 1834186 c.645C>G synonymous_variant 0.16
rpsA 1834189 c.648G>C synonymous_variant 0.16
rpsA 1834195 c.654G>C synonymous_variant 0.18
rpsA 1834213 c.672G>C synonymous_variant 0.18
rpsA 1834222 c.681T>C synonymous_variant 0.18
rpsA 1834225 c.684C>G synonymous_variant 0.18
rpsA 1834249 c.708T>C synonymous_variant 0.14
rpsA 1834261 c.720A>G synonymous_variant 0.15
rpsA 1834264 c.723G>C synonymous_variant 0.15
rpsA 1834303 c.762T>G synonymous_variant 0.15
rpsA 1834306 c.765T>C synonymous_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518672 c.558G>C synonymous_variant 0.16
kasA 2518681 c.567C>T synonymous_variant 0.16
kasA 2518684 c.570C>A synonymous_variant 0.16
thyA 3073868 p.Thr202Ala missense_variant 0.97
thyA 3074056 p.Glu139Pro missense_variant 0.15
thyA 3074061 p.Glu137Asp missense_variant 0.15
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3877909 p.Asn200Ser missense_variant 0.16
rpoA 3877950 c.558C>T synonymous_variant 0.16
rpoA 3877971 p.Asp179Glu missense_variant 0.15
rpoA 3877986 c.522G>C synonymous_variant 0.14
rpoA 3878126 c.382C>T synonymous_variant 0.15
rpoA 3878157 c.351C>G synonymous_variant 0.15
rpoA 3878172 c.336G>C synonymous_variant 0.15
rpoA 3878193 c.315T>C synonymous_variant 0.18
rpoA 3878202 c.306G>C synonymous_variant 0.21
rpoA 3878211 c.297G>A synonymous_variant 0.18
rpoA 3878217 c.291A>G synonymous_variant 0.17
rpoA 3878376 c.132G>A synonymous_variant 0.16
rpoA 3878381 c.127C>T synonymous_variant 0.18
rpoA 3878391 c.117T>A synonymous_variant 0.19
rpoA 3878403 c.105C>T synonymous_variant 0.19
rpoA 3878406 c.102G>T synonymous_variant 0.2
rpoA 3878412 c.96C>T synonymous_variant 0.22
rpoA 3878424 c.84G>C synonymous_variant 0.19
rpoA 3878442 p.Val22Thr missense_variant 0.18
rpoA 3878454 c.54A>G synonymous_variant 0.19
rpoA 3878472 p.Asp12Glu missense_variant 0.17
rpoA 3878478 c.30C>G synonymous_variant 0.18
rpoA 3878483 c.25C>T synonymous_variant 0.17
rpoA 3878490 c.18C>T synonymous_variant 0.17
rpoA 3878496 c.12A>T synonymous_variant 0.17
rpoA 3878512 c.-6_-5insGAA upstream_gene_variant 0.17
rpoA 3878548 c.-41C>A upstream_gene_variant 0.15
clpC1 4038287 c.2418C>T synonymous_variant 0.86
clpC1 4038302 c.2403C>G synonymous_variant 0.16
clpC1 4038308 c.2397G>C synonymous_variant 0.16
clpC1 4038314 c.2391T>G synonymous_variant 0.16
clpC1 4038335 c.2370C>T synonymous_variant 0.19
clpC1 4038344 c.2361G>A synonymous_variant 0.16
clpC1 4038350 c.2355C>G synonymous_variant 0.16
clpC1 4038356 c.2349T>C synonymous_variant 0.15
clpC1 4038359 c.2346A>G synonymous_variant 0.17
clpC1 4038368 c.2337T>C synonymous_variant 0.18
clpC1 4038383 c.2322G>A synonymous_variant 0.18
clpC1 4038388 c.2317T>C synonymous_variant 0.18
clpC1 4038392 c.2313C>T synonymous_variant 0.18
clpC1 4038398 c.2307G>T synonymous_variant 0.18
clpC1 4038403 c.2302T>C synonymous_variant 0.16
clpC1 4038407 c.2298G>C synonymous_variant 0.16
clpC1 4038419 c.2286T>C synonymous_variant 0.14
clpC1 4038436 p.Ala757Ser missense_variant 0.16
clpC1 4038445 p.Ala754Thr missense_variant 0.15
clpC1 4038446 c.2259T>C synonymous_variant 0.15
clpC1 4038456 p.Val750Glu missense_variant 0.14
clpC1 4038508 c.2197C>T synonymous_variant 0.19
clpC1 4038519 p.Arg729Gln missense_variant 0.18
clpC1 4038530 p.Glu725Asp missense_variant 0.17
clpC1 4038536 c.2169C>T synonymous_variant 0.15
clpC1 4038838 c.1867C>T synonymous_variant 0.16
clpC1 4038839 c.1866G>C synonymous_variant 0.17
clpC1 4038878 c.1827A>G synonymous_variant 0.18
clpC1 4038902 c.1803C>T synonymous_variant 0.22
clpC1 4038908 c.1797C>G synonymous_variant 0.2
clpC1 4038914 c.1791G>C synonymous_variant 0.2
clpC1 4038923 c.1782A>G synonymous_variant 0.18
clpC1 4038953 c.1752A>G synonymous_variant 0.17
clpC1 4038956 c.1749T>C synonymous_variant 0.17
clpC1 4038965 c.1740T>C synonymous_variant 0.17
clpC1 4038971 c.1734T>C synonymous_variant 0.19
clpC1 4038974 c.1731T>C synonymous_variant 0.17
clpC1 4038980 c.1725C>T synonymous_variant 0.17
clpC1 4038989 c.1716T>C synonymous_variant 0.16
clpC1 4038995 c.1710G>A synonymous_variant 0.16
clpC1 4039037 c.1668T>C synonymous_variant 0.18
clpC1 4039085 c.1620A>G synonymous_variant 0.18
clpC1 4039090 c.1615C>T synonymous_variant 0.18
clpC1 4039097 c.1608G>C synonymous_variant 0.18
clpC1 4039103 c.1602T>C synonymous_variant 0.18
clpC1 4039106 c.1599G>C synonymous_variant 0.19
clpC1 4039112 c.1593C>G synonymous_variant 0.19
clpC1 4039121 c.1584T>C synonymous_variant 0.18
clpC1 4039133 c.1572C>G synonymous_variant 0.19
clpC1 4039142 c.1563A>G synonymous_variant 0.2
clpC1 4039145 c.1560G>C synonymous_variant 0.2
clpC1 4039169 p.Glu512Asp missense_variant 0.19
clpC1 4039172 c.1533A>G synonymous_variant 0.19
clpC1 4039183 c.1522T>C synonymous_variant 0.19
clpC1 4039187 c.1518G>C synonymous_variant 0.17
clpC1 4039226 c.1479T>C synonymous_variant 0.17
clpC1 4039274 c.1431G>C synonymous_variant 0.17
clpC1 4039286 c.1419T>C synonymous_variant 0.2
clpC1 4039292 c.1413C>T synonymous_variant 0.23
clpC1 4039295 c.1410A>G synonymous_variant 0.22
clpC1 4039319 c.1386T>C synonymous_variant 0.2
clpC1 4039322 c.1383T>C synonymous_variant 0.19
clpC1 4039337 c.1368A>C synonymous_variant 0.19
clpC1 4039352 c.1353C>T synonymous_variant 0.2
clpC1 4039391 c.1314T>G synonymous_variant 0.19
clpC1 4039409 c.1296T>C synonymous_variant 0.18
clpC1 4039412 c.1293T>G synonymous_variant 0.18
clpC1 4039991 c.714G>C synonymous_variant 0.18
clpC1 4039996 p.Glu237Gln missense_variant 0.17
clpC1 4040015 c.690G>C synonymous_variant 0.19
clpC1 4040018 c.687G>C synonymous_variant 0.18
clpC1 4040021 c.684A>C synonymous_variant 0.17
clpC1 4040033 c.672G>C synonymous_variant 0.18
clpC1 4040036 c.669C>G synonymous_variant 0.16
clpC1 4040048 c.657C>T synonymous_variant 0.16
embC 4240795 c.933C>G synonymous_variant 0.15
embC 4241039 p.Asp393Asn missense_variant 0.14
embC 4241050 c.1188T>G synonymous_variant 0.16
embC 4241095 c.1233C>T synonymous_variant 0.16
embC 4241107 c.1245G>C synonymous_variant 0.16
embC 4241140 c.1278A>G synonymous_variant 0.16
embC 4241161 c.1299C>G synonymous_variant 0.15
embC 4241167 c.1305C>G synonymous_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4245803 c.-711C>T upstream_gene_variant 0.15
embB 4245806 c.-708G>A upstream_gene_variant 0.15
embB 4245809 c.-705A>G upstream_gene_variant 0.16
embB 4245812 c.-702G>T upstream_gene_variant 0.16
embA 4245813 p.Pro861Ala missense_variant 0.16
embA 4245822 p.Pro864Ala missense_variant 0.15
embB 4245839 c.-675G>C upstream_gene_variant 0.14
embB 4245875 c.-639G>A upstream_gene_variant 0.16
embA 4246254 p.Leu1008Met missense_variant 0.15
embB 4246259 c.-255G>C upstream_gene_variant 0.16
embA 4246279 p.Ala1016Val missense_variant 0.15
embB 4246292 c.-222A>G upstream_gene_variant 0.15
embB 4247743 c.1230C>G synonymous_variant 0.15
embB 4248070 c.1557T>C synonymous_variant 0.14
embB 4248094 c.1581C>T synonymous_variant 0.15
embB 4248142 c.1629T>C synonymous_variant 0.16
embB 4248143 c.1630T>C synonymous_variant 0.17
embB 4248154 c.1641G>T synonymous_variant 0.17
embB 4248157 c.1644A>T synonymous_variant 0.18
embB 4248163 c.1650G>A synonymous_variant 0.17
embB 4248169 c.1656C>T synonymous_variant 0.17
embB 4248175 c.1662G>A synonymous_variant 0.16
embB 4248178 c.1665C>T synonymous_variant 0.16
embB 4248206 p.Ser565Gly missense_variant 0.15
embB 4248220 c.1707A>G synonymous_variant 0.14
embB 4248233 c.1720C>T synonymous_variant 0.17
embB 4248252 p.Gly580Ala missense_variant 0.2
embB 4248266 c.1753C>T synonymous_variant 0.19
embB 4248277 c.1764G>C synonymous_variant 0.17
embB 4248280 c.1767C>G synonymous_variant 0.18
aftB 4267580 c.1257G>A synonymous_variant 0.15
aftB 4267592 c.1245C>G synonymous_variant 0.15
aftB 4267867 p.Leu324Val missense_variant 0.94
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407598 p.Val202Ala missense_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0