Run ID: 0bdc67e5-077e-4257-b594-96fa4b266037
Sample name:
Date: 19-04-2024 10:09:23
Number of reads: 92820
Percentage reads mapped: 0.61
Median coverage: 0
Strain:
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | ||||
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrA | 8126 | c.825G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8156 | c.855T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 8177 | c.876A>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| rpoB | 760184 | c.378A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760223 | c.417T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760235 | c.429T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 760247 | c.441C>T | synonymous_variant | 0.11 | rifampicin | |
| rpoB | 760253 | c.447T>C | synonymous_variant | 0.33 | rifampicin | |
| rpoB | 760263 | p.Met153Val | missense_variant | 0.33 | rifampicin | Uncertain significance |
| rpoB | 760274 | p.Glu156Asp | missense_variant | 0.57 | rifampicin | Uncertain significance |
| rpoB | 761021 | c.1215G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761027 | c.1221A>G | synonymous_variant | 0.92 | rifampicin | |
| rpoB | 761951 | c.2145G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoB | 761954 | c.2148C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 762434 | c.-936T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762449 | c.-921C>A | upstream_gene_variant | 0.89 | rifampicin | |
| rpoC | 762929 | c.-441G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 762962 | c.-408C>T | upstream_gene_variant | 0.13 | rifampicin | |
| rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.44 | rifampicin | |
| rpoC | 762995 | c.-375G>C | upstream_gene_variant | 0.99 | rifampicin | |
| rpoC | 763115 | c.-255T>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763127 | c.-243G>C | upstream_gene_variant | 1.0 | rifampicin | |
| rpoC | 763546 | c.177A>G | synonymous_variant | 0.94 | rifampicin | |
| rpoC | 763570 | c.201G>C | synonymous_variant | 0.55 | rifampicin | |
| rpoC | 763573 | c.204G>C | synonymous_variant | 0.11 | rifampicin | |
| rpoC | 763594 | c.225C>T | synonymous_variant | 0.83 | rifampicin | |
| rpoC | 763600 | c.231C>G | synonymous_variant | 0.9 | rifampicin | |
| rpoC | 763633 | c.264T>C | synonymous_variant | 0.98 | rifampicin | |
| rpoC | 763660 | c.291T>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 763666 | c.297G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764387 | c.1018T>C | synonymous_variant | 0.96 | rifampicin | |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 0.99 | rifampicin | |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764527 | c.1158C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764582 | p.Leu405Met | missense_variant | 0.41 | rifampicin | |
| rpoC | 764605 | c.1236G>C | synonymous_variant | 0.49 | rifampicin | |
| rpoC | 764611 | c.1242G>C | synonymous_variant | 0.49 | rifampicin | |
| rpoC | 764632 | c.1263T>C | synonymous_variant | 0.63 | rifampicin | |
| rpoC | 764644 | c.1275G>C | synonymous_variant | 0.63 | rifampicin | |
| rpoC | 764646 | p.Gly426Ala | missense_variant | 0.28 | rifampicin | |
| rpoC | 764650 | c.1281G>T | synonymous_variant | 0.34 | rifampicin | |
| rpoC | 764695 | c.1326T>C | synonymous_variant | 0.62 | rifampicin | |
| rpoC | 764758 | c.1389C>G | synonymous_variant | 1.0 | rifampicin | |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 | rifampicin | |
| rrs | 1471914 | n.69A>G | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471917 | n.72G>A | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471943 | n.98T>C | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471972 | n.127T>C | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471979 | n.134T>C | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471996 | n.151C>T | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472023 | n.178G>T | non_coding_transcript_exon_variant | 0.51 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472068 | n.223T>C | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472069 | n.224G>A | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472148 | n.303T>C | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472286 | n.441C>G | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472315 | n.470T>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472326 | n.481T>A | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472327 | n.482G>A | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472328 | n.483G>C | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472344 | n.499C>T | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472370 | n.525T>C | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472379 | n.534T>C | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472400 | n.555C>T | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472422 | n.577T>C | non_coding_transcript_exon_variant | 0.48 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472426 | n.581T>G | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472431 | n.586G>A | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472494 | n.649A>T | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472496 | n.651T>G | non_coding_transcript_exon_variant | 0.59 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472498 | n.653C>T | non_coding_transcript_exon_variant | 0.39 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472507 | n.662C>T | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472508 | n.663T>C | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472571 | n.726G>A | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472581 | n.736A>C | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472583 | n.738T>A | non_coding_transcript_exon_variant | 0.32 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 0.52 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.97 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472660 | n.815T>C | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472686 | n.841G>C | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472793 | n.948A>C | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472803 | n.958T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472840 | n.995A>C | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472841 | n.996G>A | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472873 | n.1028C>T | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472874 | n.1029C>T | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472875 | n.1030T>G | non_coding_transcript_exon_variant | 0.37 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472880 | n.1035_1036insA | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.81 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472958 | n.1113A>G | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472987 | n.1142G>A | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473026 | n.1181T>C | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473062 | n.1217T>G | non_coding_transcript_exon_variant | 0.32 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473088 | n.1243A>G | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473122 | n.1277T>A | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473201 | n.1356A>T | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473202 | n.1357C>T | non_coding_transcript_exon_variant | 0.69 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473252 | n.1407T>C | non_coding_transcript_exon_variant | 0.95 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.84 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473283 | n.1438T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473291 | n.1446G>A | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473315 | n.1470T>C | non_coding_transcript_exon_variant | 0.74 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1473391 | n.-267C>T | upstream_gene_variant | 0.66 | linezolid | |
| rrl | 1473392 | n.-266C>T | upstream_gene_variant | 0.29 | linezolid | |
| rrl | 1473699 | n.42A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473736 | n.79C>G | non_coding_transcript_exon_variant | 0.34 | linezolid | |
| rrl | 1473743 | n.86C>T | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| rrl | 1473770 | n.113T>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473833 | n.176G>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1473876 | n.219G>A | non_coding_transcript_exon_variant | 0.99 | linezolid | |
| rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1474201 | n.544T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1474232 | n.575C>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1474239 | n.582G>C | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1474275 | n.618T>G | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| rrl | 1474446 | n.789C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1474454 | n.797G>A | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| rrl | 1474455 | n.798G>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1474466 | n.809G>A | non_coding_transcript_exon_variant | 0.16 | linezolid | Uncertain significance |
| rrl | 1474476 | n.819C>T | non_coding_transcript_exon_variant | 0.66 | linezolid | |
| rrl | 1474483 | n.826C>G | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| rrl | 1474488 | n.831G>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1474508 | n.851C>T | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1474512 | n.855G>A | non_coding_transcript_exon_variant | 0.13 | linezolid | |
| rrl | 1474516 | n.859C>A | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1474527 | n.870T>C | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1474551 | n.894G>C | non_coding_transcript_exon_variant | 0.91 | linezolid | |
| rrl | 1474558 | n.901G>T | non_coding_transcript_exon_variant | 0.93 | linezolid | |
| rrl | 1474632 | n.975G>T | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1474706 | n.1049G>A | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1474753 | n.1096A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1474802 | n.1145T>C | non_coding_transcript_exon_variant | 0.82 | linezolid | |
| rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 0.98 | linezolid | |
| rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.75 | linezolid | |
| rrl | 1474904 | n.1247G>C | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1474904 | n.1247G>T | non_coding_transcript_exon_variant | 0.92 | linezolid | |
| rrl | 1474913 | n.1256T>C | non_coding_transcript_exon_variant | 0.94 | linezolid | |
| rrl | 1475082 | n.1425C>T | non_coding_transcript_exon_variant | 0.2 | linezolid | |
| rrl | 1475116 | n.1459G>A | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1475124 | n.1467A>T | non_coding_transcript_exon_variant | 0.45 | linezolid | |
| rrl | 1475129 | n.1472G>A | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| rrl | 1475171 | n.1514C>T | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| rrl | 1475191 | n.1534A>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1475194 | n.1537C>G | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1475196 | n.1539T>C | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| rrl | 1475291 | n.1634A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.73 | linezolid | |
| rrl | 1475603 | n.1946G>C | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1475655 | n.1998T>C | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1475659 | n.2002G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475661 | n.2004G>A | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1475699 | n.2042C>T | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1475740 | n.2083G>C | non_coding_transcript_exon_variant | 0.85 | linezolid | |
| rrl | 1475747 | n.2090A>G | non_coding_transcript_exon_variant | 0.38 | linezolid | |
| rrl | 1475756 | n.2099T>C | non_coding_transcript_exon_variant | 0.78 | linezolid | |
| rrl | 1475781 | n.2124T>C | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| rrl | 1475788 | n.2131C>G | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| rrl | 1475883 | n.2226A>G | non_coding_transcript_exon_variant | 0.87 | linezolid | |
| rrl | 1475884 | n.2227A>G | non_coding_transcript_exon_variant | 0.83 | linezolid | |
| rrl | 1475896 | n.2239A>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1475897 | n.2240T>C | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1475943 | n.2286G>A | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1475952 | n.2295A>G | non_coding_transcript_exon_variant | 0.89 | linezolid | |
| rrl | 1475970 | n.2313C>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| rrl | 1475995 | n.2338G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1475997 | n.2340A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476032 | n.2375C>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476088 | n.2431A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476108 | n.2451T>C | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476119 | n.2462G>A | non_coding_transcript_exon_variant | 0.79 | linezolid | |
| rrl | 1476131 | n.2474C>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1476164 | n.2507A>G | non_coding_transcript_exon_variant | 0.6 | linezolid | |
| rrl | 1476165 | n.2508T>G | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| rrl | 1476194 | n.2537A>G | non_coding_transcript_exon_variant | 0.5 | linezolid | Uncertain significance |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.9 | linezolid | |
| rrl | 1476300 | n.2643G>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| rrl | 1476309 | n.2652G>C | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.14 | linezolid | |
| rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.96 | linezolid | |
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.78 | linezolid | Uncertain significance |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1833949 | c.408T>C | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834030 | c.489C>G | synonymous_variant | 0.95 | pyrazinamide | |
| rpsA | 1834034 | p.Ile165Val | missense_variant | 0.97 | pyrazinamide | |
| rpsA | 1834046 | p.Ile169Leu | missense_variant | 0.96 | pyrazinamide | |
| rpsA | 1834093 | c.552G>C | synonymous_variant | 0.75 | pyrazinamide | |
| rpsA | 1834096 | c.555G>C | synonymous_variant | 0.28 | pyrazinamide | |
| rpsA | 1834102 | c.561T>C | synonymous_variant | 0.99 | pyrazinamide | |
| rpsA | 1834366 | c.825A>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834369 | c.828C>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834489 | c.948T>C | synonymous_variant | 0.96 | pyrazinamide | |
| rpsA | 1834528 | c.987T>G | synonymous_variant | 1.0 | pyrazinamide | |
| rpsA | 1834690 | c.1149T>C | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038575 | c.2130C>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4039489 | p.Ala406Thr | missense_variant | 0.25 | pyrazinamide | |
| clpC1 | 4039533 | p.Asn391Ser | missense_variant | 0.92 | pyrazinamide | |
| clpC1 | 4039855 | c.850C>T | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040024 | c.681A>G | synonymous_variant | 1.0 | pyrazinamide | |
| clpC1 | 4040027 | c.678C>G | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040033 | c.672G>C | synonymous_variant | 0.99 | pyrazinamide | |
| clpC1 | 4040084 | c.621C>T | synonymous_variant | 0.69 | pyrazinamide | |
| clpC1 | 4040087 | c.618G>C | synonymous_variant | 0.55 | pyrazinamide | |
| clpC1 | 4040090 | c.615T>G | synonymous_variant | 0.95 | pyrazinamide | |
| clpC1 | 4040606 | c.99T>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040644 | c.61A>C | synonymous_variant | 0.98 | pyrazinamide | |
| clpC1 | 4040657 | c.48T>C | synonymous_variant | 0.94 | pyrazinamide | |
| clpC1 | 4040669 | c.36C>T | synonymous_variant | 1.0 | pyrazinamide |
