TB-Profiler result

Run: ERR400538
Summary

Run ID: ERR400538

Sample name:

Date: 01-04-2023 03:52:28

Number of reads: 1746642

Percentage reads mapped: 75.88

Strain: lineage5.1.2

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage5 West-Africa 1 AFRI_2;AFRI_3 RD711 0.98
lineage5.1.2 West-Africa 1 AFRI_2;AFRI_3 RD711 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761139 p.His445Asp missense_variant 0.86 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 0.89 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 6841 c.-461T>C upstream_gene_variant 0.13
gyrA 7006 c.-296T>G upstream_gene_variant 0.14
gyrB 7010 p.Leu591Met missense_variant 0.13
gyrA 7018 c.-284G>C upstream_gene_variant 0.15
gyrA 7024 c.-278G>C upstream_gene_variant 0.17
gyrA 7033 c.-269G>C upstream_gene_variant 0.2
gyrB 7051 p.Glu604Asp missense_variant 0.18
gyrA 7060 c.-242T>C upstream_gene_variant 0.18
gyrA 7066 c.-236G>C upstream_gene_variant 0.14
gyrA 7078 c.-224A>T upstream_gene_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7532 c.231T>G synonymous_variant 0.19
gyrA 7550 c.249C>T synonymous_variant 0.21
gyrA 7559 c.258G>A synonymous_variant 0.2
gyrA 7571 c.270G>C synonymous_variant 0.21
gyrA 7574 c.273G>C synonymous_variant 0.21
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7587 c.286C>T synonymous_variant 0.13
gyrA 7595 c.294C>T synonymous_variant 0.13
gyrA 7601 c.300C>G synonymous_variant 0.14
gyrA 8324 c.1023T>C synonymous_variant 0.12
gyrA 8339 c.1038A>G synonymous_variant 0.12
gyrA 8340 p.Ala347Ser missense_variant 0.12
gyrA 8915 c.1614A>G synonymous_variant 0.16
gyrA 8924 c.1623C>T synonymous_variant 0.2
gyrA 8945 c.1644G>C synonymous_variant 0.19
gyrA 8946 c.1645_1647delTTGinsCTC synonymous_variant 0.18
gyrA 8967 p.Ala556Lys missense_variant 0.22
gyrA 8990 c.1689C>G synonymous_variant 0.18
gyrA 8993 c.1692C>T synonymous_variant 0.17
gyrA 8996 c.1695T>C synonymous_variant 0.17
gyrA 8998 p.Leu566Trp missense_variant 0.18
gyrA 9044 c.1743C>G synonymous_variant 0.12
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9566 c.2265C>T synonymous_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575756 c.409C>T synonymous_variant 0.12
rpoB 760184 c.378A>G synonymous_variant 0.21
rpoB 760196 c.390C>G synonymous_variant 0.22
rpoB 760223 c.417T>C synonymous_variant 0.21
rpoB 760235 c.429T>C synonymous_variant 0.24
rpoB 760244 c.438G>C synonymous_variant 0.22
rpoB 760274 p.Glu156Asp missense_variant 0.11
rpoB 760370 c.564C>G synonymous_variant 0.14
rpoB 760376 p.Asp190Glu missense_variant 0.14
rpoB 760382 c.576G>C synonymous_variant 0.15
rpoB 760400 c.594G>C synonymous_variant 0.16
rpoB 760406 c.600G>C synonymous_variant 0.16
rpoB 760407 p.Ser201Gly missense_variant 0.16
rpoB 760412 c.606C>T synonymous_variant 0.15
rpoB 760415 c.609C>T synonymous_variant 0.15
rpoB 760418 c.612G>A synonymous_variant 0.14
rpoB 760430 c.624T>C synonymous_variant 0.15
rpoB 760433 c.627C>T synonymous_variant 0.19
rpoB 760454 c.648C>G synonymous_variant 0.18
rpoB 760457 c.651C>T synonymous_variant 0.19
rpoB 760469 c.663C>T synonymous_variant 0.13
rpoB 760522 p.Ser239Asn missense_variant 0.16
rpoB 760532 c.726T>C synonymous_variant 0.12
rpoB 760541 c.735G>T synonymous_variant 0.14
rpoB 760561 c.757_758delCG frameshift_variant 0.15
rpoB 760571 c.765G>C synonymous_variant 0.16
rpoB 760588 p.Thr261Ile missense_variant 0.15
rpoB 760591 p.Val262Ala missense_variant 0.15
rpoB 760595 c.789C>T synonymous_variant 0.14
rpoB 760596 p.Thr264Pro missense_variant 0.14
rpoB 760607 c.801G>C synonymous_variant 0.18
rpoB 760611 c.805T>C synonymous_variant 0.21
rpoB 760634 c.828T>C synonymous_variant 0.21
rpoB 760646 c.840C>G synonymous_variant 0.2
rpoB 760655 c.849A>G synonymous_variant 0.22
rpoB 760661 c.855A>C synonymous_variant 0.23
rpoB 760668 p.Thr288Ala missense_variant 0.22
rpoB 760674 c.868T>C synonymous_variant 0.21
rpoB 760679 c.873A>G synonymous_variant 0.2
rpoB 760683 c.877T>C synonymous_variant 0.17
rpoB 760703 c.897C>T synonymous_variant 0.16
rpoB 760858 p.Val351Ala missense_variant 0.11
rpoB 760869 p.Val355Leu missense_variant 0.12
rpoB 760877 c.1071G>C synonymous_variant 0.12
rpoB 760883 c.1077G>C synonymous_variant 0.12
rpoB 760886 c.1080A>G synonymous_variant 0.12
rpoB 760887 p.Thr361Ala missense_variant 0.12
rpoB 761084 c.1278C>A synonymous_variant 0.17
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.15
rpoB 761102 c.1296A>G synonymous_variant 0.17
rpoB 761132 c.1326G>T synonymous_variant 0.14
rpoB 761133 c.1327T>C synonymous_variant 0.14
rpoB 761147 c.1341C>T synonymous_variant 0.17
rpoB 761150 c.1344A>T synonymous_variant 0.16
rpoB 761159 c.1353G>T synonymous_variant 0.16
rpoB 761165 c.1359G>C synonymous_variant 0.13
rpoB 761171 c.1365C>T synonymous_variant 0.13
rpoB 761219 c.1413G>C synonymous_variant 0.13
rpoB 761234 c.1428G>C synonymous_variant 0.2
rpoB 761249 c.1443A>G synonymous_variant 0.15
rpoB 761255 c.1449T>G synonymous_variant 0.14
rpoB 761258 c.1452G>A synonymous_variant 0.13
rpoB 761261 c.1455G>C synonymous_variant 0.13
rpoB 761264 c.1458C>G synonymous_variant 0.15
rpoB 761273 c.1467T>C synonymous_variant 0.15
rpoB 761282 c.1476C>T synonymous_variant 0.16
rpoB 761288 c.1482G>T synonymous_variant 0.16
rpoB 761579 c.1773G>C synonymous_variant 0.11
rpoB 761612 c.1806G>T synonymous_variant 0.15
rpoB 761615 c.1809A>C synonymous_variant 0.16
rpoB 761636 c.1830G>T synonymous_variant 0.13
rpoB 761645 c.1839C>G synonymous_variant 0.13
rpoB 761990 c.2184G>C synonymous_variant 0.11
rpoB 762008 c.2202C>T synonymous_variant 0.2
rpoB 762014 c.2208C>G synonymous_variant 0.21
rpoB 762038 c.2232C>T synonymous_variant 0.17
rpoB 762047 c.2241G>A synonymous_variant 0.19
rpoB 762053 c.2247T>C synonymous_variant 0.2
rpoB 762056 c.2250G>A synonymous_variant 0.2
rpoB 762065 c.2259T>G synonymous_variant 0.21
rpoB 762083 c.2277T>C synonymous_variant 0.19
rpoB 762086 c.2280G>T synonymous_variant 0.19
rpoB 762101 c.2295C>G synonymous_variant 0.16
rpoB 762114 p.Ile770Val missense_variant 0.12
rpoB 762167 c.2361T>C synonymous_variant 0.13
rpoB 762185 c.2379G>C synonymous_variant 0.11
rpoB 762221 c.2415G>A synonymous_variant 0.22
rpoB 762233 c.2427G>C synonymous_variant 0.21
rpoB 762236 c.2430G>C synonymous_variant 0.23
rpoB 762245 c.2439G>C synonymous_variant 0.21
rpoB 762879 p.Met1025Leu missense_variant 0.12
rpoC 762894 c.-476C>T upstream_gene_variant 0.12
rpoC 762899 c.-471G>C upstream_gene_variant 0.11
rpoC 762911 c.-459C>T upstream_gene_variant 0.16
rpoC 762917 c.-453C>G upstream_gene_variant 0.15
rpoC 762920 c.-450C>T upstream_gene_variant 0.13
rpoC 762923 c.-447C>G upstream_gene_variant 0.13
rpoC 762959 c.-411G>C upstream_gene_variant 0.15
rpoC 762962 c.-408C>T upstream_gene_variant 0.16
rpoC 762983 c.-387C>T upstream_gene_variant 0.15
rpoC 762989 c.-381G>A upstream_gene_variant 0.16
rpoC 762995 c.-375G>T upstream_gene_variant 0.15
rpoC 763031 c.-339T>G upstream_gene_variant 1.0
rpoC 763034 c.-336C>A upstream_gene_variant 0.23
rpoC 763040 c.-330C>G upstream_gene_variant 0.27
rpoC 763070 c.-300T>C upstream_gene_variant 0.27
rpoC 763082 c.-288C>T upstream_gene_variant 0.28
rpoC 763085 c.-285C>T upstream_gene_variant 0.29
rpoC 763088 c.-282C>G upstream_gene_variant 0.29
rpoC 763094 c.-276G>C upstream_gene_variant 0.28
rpoC 763115 c.-255T>C upstream_gene_variant 0.23
rpoC 763127 c.-243G>C upstream_gene_variant 0.14
rpoC 763528 c.159G>A synonymous_variant 0.2
rpoC 763531 c.162G>T synonymous_variant 0.21
rpoC 763546 c.177A>G synonymous_variant 0.27
rpoC 763570 c.201G>C synonymous_variant 0.3
rpoC 763594 c.225C>T synonymous_variant 0.36
rpoC 763618 c.249C>T synonymous_variant 0.3
rpoC 763633 c.264T>C synonymous_variant 0.21
rpoC 763660 c.291T>G synonymous_variant 0.22
rpoC 763669 c.300C>G synonymous_variant 0.19
rpoC 763675 c.306C>G synonymous_variant 0.16
rpoC 763741 c.372C>T synonymous_variant 0.12
rpoC 763747 c.378G>A synonymous_variant 0.13
rpoC 764365 c.996C>T synonymous_variant 0.16
rpoC 764371 c.1002G>T synonymous_variant 0.18
rpoC 764377 c.1008C>G synonymous_variant 0.19
rpoC 764380 c.1011G>C synonymous_variant 0.18
rpoC 764383 c.1014C>T synonymous_variant 0.18
rpoC 764387 c.1018T>C synonymous_variant 0.18
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.19
rpoC 764428 c.1059G>C synonymous_variant 0.18
rpoC 764431 c.1062G>C synonymous_variant 0.18
rpoC 764434 c.1065A>G synonymous_variant 0.17
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.18
rpoC 764458 c.1089G>C synonymous_variant 0.2
rpoC 764461 c.1092A>G synonymous_variant 0.17
rpoC 764497 c.1128A>G synonymous_variant 0.22
rpoC 764506 c.1137C>T synonymous_variant 0.22
rpoC 764527 c.1158C>T synonymous_variant 0.13
rpoC 764530 c.1161C>T synonymous_variant 0.14
rpoC 764533 c.1164C>A synonymous_variant 0.13
rpoC 764536 c.1167G>T synonymous_variant 0.14
rpoC 764539 c.1170C>G synonymous_variant 0.15
rpoC 764548 c.1179G>A synonymous_variant 0.14
rpoC 764554 c.1185C>T synonymous_variant 0.15
rpoC 764566 c.1197C>G synonymous_variant 0.21
rpoC 764575 c.1206T>G synonymous_variant 0.15
rpoC 764578 c.1209C>G synonymous_variant 0.16
rpoC 764602 c.1233C>T synonymous_variant 0.13
rpoC 764611 c.1242G>T synonymous_variant 0.14
rpoC 764626 c.1257C>T synonymous_variant 0.18
rpoC 764632 c.1263T>C synonymous_variant 0.18
rpoC 764635 c.1266C>T synonymous_variant 0.17
rpoC 764650 c.1281G>T synonymous_variant 0.12
rpoC 764713 c.1344G>T synonymous_variant 0.27
rpoC 764746 c.1377G>T synonymous_variant 0.31
rpoC 764752 c.1383G>C synonymous_variant 0.33
rpoC 764758 c.1389C>G synonymous_variant 0.33
rpoC 764764 c.1395T>C synonymous_variant 0.33
rpoC 764803 c.1434C>T synonymous_variant 0.32
rpoC 764810 p.Pro481Ala missense_variant 0.28
rpoC 764815 c.1446A>G synonymous_variant 0.28
rpoC 764827 c.1458G>C synonymous_variant 0.23
rpoC 764858 c.1489T>C synonymous_variant 0.19
rpoC 764869 c.1500C>T synonymous_variant 0.17
rpoC 764875 c.1506C>A synonymous_variant 0.18
rpoC 764878 c.1509C>G synonymous_variant 0.18
rpoC 764887 c.1518G>C synonymous_variant 0.19
rpoC 764888 c.1519T>C synonymous_variant 0.2
rpoC 764911 c.1542A>G synonymous_variant 0.22
rpoC 764912 p.Met515Gln missense_variant 0.22
rpoC 764932 c.1563C>A synonymous_variant 0.22
rpoC 764948 c.1579T>C synonymous_variant 0.21
rpoC 764968 c.1599T>C synonymous_variant 0.18
rpoC 765073 c.1704G>C synonymous_variant 0.14
rpoC 765076 c.1707A>G synonymous_variant 0.14
rpoC 765079 c.1710T>G synonymous_variant 0.14
rpoC 765082 c.1713G>C synonymous_variant 0.14
rpoC 765085 c.1716T>C synonymous_variant 0.14
rpoC 765089 c.1720T>C synonymous_variant 0.13
rpoC 765383 p.Met672Leu missense_variant 0.11
rpoC 765394 c.2025G>A synonymous_variant 0.15
rpoC 765403 c.2034G>C synonymous_variant 0.18
rpoC 765405 p.Leu679His missense_variant 0.17
rpoC 765409 c.2040T>G synonymous_variant 0.17
rpoC 765412 c.2043T>C synonymous_variant 0.17
rpoC 765421 c.2052C>G synonymous_variant 0.17
rpoC 765449 p.Ala694Ser missense_variant 0.13
rpoC 765454 c.2085C>G synonymous_variant 0.13
rpoC 765861 p.Phe831Tyr missense_variant 0.14
rpoC 765868 c.2499G>A synonymous_variant 0.16
rpoC 765871 c.2502T>G synonymous_variant 0.15
rpoC 765875 p.Val836Ile missense_variant 0.2
rpoC 765886 c.2517C>G synonymous_variant 0.19
rpoC 765907 c.2538G>T synonymous_variant 0.21
rpoC 765928 c.2559C>G synonymous_variant 0.23
rpoC 765937 c.2568T>C synonymous_variant 0.18
rpoC 765940 c.2571A>T synonymous_variant 0.16
rpoC 765946 c.2577C>T synonymous_variant 0.13
rpoC 765947 c.2578T>C synonymous_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781628 c.69T>C synonymous_variant 0.12
rpsL 781649 c.90T>C synonymous_variant 0.13
rpsL 781655 c.96T>C synonymous_variant 0.13
rpsL 781658 c.99A>G synonymous_variant 0.14
rpsL 781670 c.111G>C synonymous_variant 0.14
rpsL 781808 c.249C>T synonymous_variant 0.12
rpsL 781811 c.252C>T synonymous_variant 0.12
rpsL 781829 c.270G>C synonymous_variant 0.12
rpsL 781832 c.273T>C synonymous_variant 0.17
rpsL 781859 c.300T>C synonymous_variant 0.13
rpsL 781868 c.309T>C synonymous_variant 0.13
rpsL 781871 c.312G>C synonymous_variant 0.11
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1303566 c.636C>G synonymous_variant 0.13
Rv1258c 1407273 p.Asp23Val missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.17
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.16
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.19
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.22
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.26
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.31
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.33
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.3
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.28
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.25
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.22
rrs 1472846 n.1001C>T non_coding_transcript_exon_variant 0.15
rrs 1472847 n.1002G>A non_coding_transcript_exon_variant 0.14
rrs 1472848 n.1003T>C non_coding_transcript_exon_variant 0.15
rrs 1472860 n.1015C>T non_coding_transcript_exon_variant 0.14
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.12
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.16
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.16
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.16
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.16
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.17
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.17
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.25
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.24
rrs 1473099 n.1254T>A non_coding_transcript_exon_variant 0.2
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.21
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.19
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.19
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.21
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.21
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.19
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.18
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.17
rrs 1473288 n.1443C>T non_coding_transcript_exon_variant 0.18
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.18
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.18
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.12
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.14
rrl 1473839 n.182G>A non_coding_transcript_exon_variant 0.13
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.16
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.12
rrl 1473888 n.231T>C non_coding_transcript_exon_variant 0.12
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.14
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.14
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.15
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.14
rrl 1473924 n.267_268insT non_coding_transcript_exon_variant 0.14
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.14
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.17
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.18
rrl 1474181 n.524_525insT non_coding_transcript_exon_variant 0.17
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.17
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.17
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.2
rrl 1474263 n.606G>A non_coding_transcript_exon_variant 0.18
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.17
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.15
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.13
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.19
rrl 1474507 n.850G>C non_coding_transcript_exon_variant 0.19
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.14
rrl 1474630 n.973T>C non_coding_transcript_exon_variant 0.13
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.13
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.14
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.13
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.14
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.14
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.14
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.16
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.17
rrl 1474743 n.1086T>G non_coding_transcript_exon_variant 0.19
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.14
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.17
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.19
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.21
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.21
rrl 1475061 n.1406delA non_coding_transcript_exon_variant 0.22
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.19
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.26
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.36
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.32
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.3
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.14
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.16
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.2
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.23
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.23
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.23
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.28
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.21
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.21
rrl 1475760 n.2105_2106delGC non_coding_transcript_exon_variant 0.22
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.22
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.22
rrl 1475954 n.2297A>G non_coding_transcript_exon_variant 0.16
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.24
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.22
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.2
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.22
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.35
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.25
rrl 1476295 n.2638C>T non_coding_transcript_exon_variant 0.19
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.2
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.19
rrl 1476311 n.2654G>A non_coding_transcript_exon_variant 0.18
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.27
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.23
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.22
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.19
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.18
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.15
inhA 1673338 c.-864G>A upstream_gene_variant 1.0
inhA 1674114 c.-88T>G upstream_gene_variant 0.14
inhA 1674126 c.-76G>C upstream_gene_variant 0.13
inhA 1674129 c.-73C>T upstream_gene_variant 0.13
inhA 1674132 c.-70T>C upstream_gene_variant 0.14
rpsA 1833583 c.42C>T synonymous_variant 0.16
rpsA 1833589 c.48A>C synonymous_variant 0.14
rpsA 1833595 c.54T>G synonymous_variant 0.14
rpsA 1833596 p.Ser19Ala missense_variant 0.14
rpsA 1833604 c.63C>T synonymous_variant 0.16
rpsA 1833616 c.75A>T synonymous_variant 0.17
rpsA 1833619 c.78A>C synonymous_variant 0.17
rpsA 1833625 c.84A>G synonymous_variant 0.21
rpsA 1833661 c.120A>G synonymous_variant 0.15
rpsA 1833664 c.123C>G synonymous_variant 0.15
rpsA 1833676 c.135A>G synonymous_variant 0.16
rpsA 1833697 c.156C>T synonymous_variant 0.16
rpsA 1833700 c.159C>T synonymous_variant 0.17
rpsA 1833709 c.168C>T synonymous_variant 0.17
rpsA 1833787 c.246C>G synonymous_variant 0.13
rpsA 1833790 c.249T>C synonymous_variant 0.12
rpsA 1833829 c.288A>G synonymous_variant 0.19
rpsA 1833832 c.291G>A synonymous_variant 0.19
rpsA 1833838 c.297G>T synonymous_variant 0.15
rpsA 1833841 c.300C>G synonymous_variant 0.15
rpsA 1833847 c.306C>G synonymous_variant 0.17
rpsA 1833856 c.315A>G synonymous_variant 0.15
rpsA 1833862 c.321G>T synonymous_variant 0.16
rpsA 1833874 c.333T>G synonymous_variant 0.13
rpsA 1833886 c.345C>G synonymous_variant 0.14
rpsA 1833892 c.351G>A synonymous_variant 0.13
rpsA 1833894 p.Ala118Glu missense_variant 0.13
rpsA 1833928 c.387G>C synonymous_variant 0.14
rpsA 1833949 c.408T>C synonymous_variant 0.16
rpsA 1833970 c.429G>C synonymous_variant 0.23
rpsA 1833979 c.438T>C synonymous_variant 0.2
rpsA 1833991 c.450C>G synonymous_variant 0.21
rpsA 1834000 c.459G>C synonymous_variant 0.21
rpsA 1834009 c.468C>T synonymous_variant 0.15
rpsA 1834012 c.471G>T synonymous_variant 0.14
rpsA 1834015 c.474G>C synonymous_variant 0.17
rpsA 1834021 c.480C>T synonymous_variant 0.17
rpsA 1834030 c.489C>G synonymous_variant 0.18
rpsA 1834033 c.492C>T synonymous_variant 0.17
rpsA 1834069 c.528G>C synonymous_variant 0.15
rpsA 1834073 p.Lys178Arg missense_variant 0.12
rpsA 1834228 c.687C>A synonymous_variant 0.14
rpsA 1834231 c.690T>G synonymous_variant 0.15
rpsA 1834234 c.693G>T synonymous_variant 0.15
rpsA 1834240 c.699T>C synonymous_variant 0.15
rpsA 1834246 c.705G>T synonymous_variant 0.16
rpsA 1834249 c.708T>C synonymous_variant 0.17
rpsA 1834252 c.711C>G synonymous_variant 0.17
rpsA 1834261 c.720A>G synonymous_variant 0.16
rpsA 1834264 c.723G>C synonymous_variant 0.21
rpsA 1834297 c.756C>T synonymous_variant 0.31
rpsA 1834303 c.762T>G synonymous_variant 0.27
rpsA 1834306 c.765T>C synonymous_variant 0.27
rpsA 1834339 c.798C>T synonymous_variant 0.21
rpsA 1834348 c.807T>C synonymous_variant 0.2
rpsA 1834366 c.825A>G synonymous_variant 0.14
rpsA 1834375 c.834G>A synonymous_variant 0.12
rpsA 1834435 c.894G>C synonymous_variant 0.12
rpsA 1834451 c.910T>C synonymous_variant 0.15
rpsA 1834456 c.915T>G synonymous_variant 0.15
rpsA 1834468 c.927A>G synonymous_variant 0.15
rpsA 1834480 c.939C>G synonymous_variant 0.12
rpsA 1834483 c.942G>A synonymous_variant 0.13
rpsA 1834489 c.948T>C synonymous_variant 0.17
rpsA 1834498 c.957C>T synonymous_variant 0.19
rpsA 1834520 p.Ala327Ser missense_variant 0.18
rpsA 1834528 c.987T>C synonymous_variant 0.19
rpsA 1834543 c.1002C>G synonymous_variant 0.13
rpsA 1834555 c.1014T>G synonymous_variant 0.12
rpsA 1834557 p.Ala339Gly missense_variant 0.13
rpsA 1834606 c.1065C>T synonymous_variant 0.15
rpsA 1834612 c.1071G>C synonymous_variant 0.13
rpsA 1834619 c.1078T>C synonymous_variant 0.13
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.14
rpsA 1834633 c.1092A>G synonymous_variant 0.2
rpsA 1834639 c.1098T>C synonymous_variant 0.21
rpsA 1834666 c.1125G>C synonymous_variant 0.17
rpsA 1834667 p.Ala376Ser missense_variant 0.17
rpsA 1834684 c.1143C>G synonymous_variant 0.14
rpsA 1834701 p.Gln387Pro missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101921 c.1122G>A synonymous_variant 1.0
ndh 2103112 c.-70G>T upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170265 c.347delG frameshift_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290062 c.-821G>A upstream_gene_variant 0.97
kasA 2517917 c.-198G>C upstream_gene_variant 0.17
kasA 2518132 c.18C>T synonymous_variant 1.0
ahpC 2726261 c.69G>T synonymous_variant 1.0
thyA 3073950 c.522G>T synonymous_variant 0.13
thyA 3073953 c.519T>C synonymous_variant 0.12
thyA 3073956 c.516G>C synonymous_variant 0.12
ald 3087084 c.266delA frameshift_variant 1.0
ald 3087184 c.368_373delCCGACG disruptive_inframe_deletion 1.0
Rv3083 3449644 p.Ala381Thr missense_variant 1.0
Rv3083 3449792 p.Ala430Gly missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
fbiB 3641490 c.-45G>A upstream_gene_variant 1.0
alr 3840932 c.489C>T synonymous_variant 1.0
rpoA 3877587 c.921A>G synonymous_variant 0.16
rpoA 3877596 c.912G>C synonymous_variant 0.19
rpoA 3877602 c.906C>T synonymous_variant 0.18
rpoA 3877656 c.852T>G synonymous_variant 0.16
rpoA 3877662 c.846C>T synonymous_variant 0.16
rpoA 3877665 c.843C>G synonymous_variant 0.16
rpoA 3877668 c.840A>G synonymous_variant 0.17
rpoA 3877677 c.831G>C synonymous_variant 0.13
rpoA 3877680 c.828G>T synonymous_variant 0.13
rpoA 3877686 c.822A>G synonymous_variant 0.13
rpoA 3877692 c.816G>C synonymous_variant 0.13
rpoA 3877704 c.804G>T synonymous_variant 0.15
rpoA 3877728 c.780C>G synonymous_variant 0.16
rpoA 3877734 c.774G>C synonymous_variant 0.2
rpoA 3877737 c.771G>C synonymous_variant 0.21
rpoA 3877743 c.765T>C synonymous_variant 0.19
rpoA 3877752 p.Asp252Glu missense_variant 0.2
rpoA 3877758 c.750G>C synonymous_variant 0.21
rpoA 3877764 c.744C>G synonymous_variant 0.17
rpoA 3877770 c.738A>G synonymous_variant 0.17
rpoA 3877773 c.735G>C synonymous_variant 0.19
rpoA 3877776 c.732T>C synonymous_variant 0.19
rpoA 3877782 c.726T>C synonymous_variant 0.19
rpoA 3877785 c.723C>A synonymous_variant 0.19
rpoA 3877818 c.690A>G synonymous_variant 0.17
rpoA 3877875 c.633T>C synonymous_variant 0.12
rpoA 3877881 c.627G>C synonymous_variant 0.12
rpoA 3877887 c.621G>C synonymous_variant 0.15
rpoA 3877893 c.615C>T synonymous_variant 0.14
rpoA 3877900 p.Ser203Thr missense_variant 0.14
rpoA 3877905 c.603A>G synonymous_variant 0.15
rpoA 3877908 c.600T>C synonymous_variant 0.14
rpoA 3877920 c.588G>C synonymous_variant 0.14
rpoA 3877923 c.585C>T synonymous_variant 0.13
rpoA 3877926 c.582G>C synonymous_variant 0.14
rpoA 3877929 p.Ile193Val missense_variant 0.14
rpoA 3878127 c.381G>C synonymous_variant 0.11
rpoA 3878130 c.378C>G synonymous_variant 0.11
rpoA 3878169 c.339G>C synonymous_variant 0.12
rpoA 3878205 c.303T>A synonymous_variant 0.14
rpoA 3878217 c.291A>G synonymous_variant 0.18
rpoA 3878259 c.249G>C synonymous_variant 0.17
rpoA 3878271 c.237T>C synonymous_variant 0.11
rpoA 3878274 c.234G>C synonymous_variant 0.12
rpoA 3878346 c.162T>C synonymous_variant 0.1
rpoA 3878364 c.144A>C synonymous_variant 0.12
rpoA 3878367 c.141C>G synonymous_variant 0.12
rpoA 3878370 c.138T>C synonymous_variant 0.12
rpoA 3878373 c.135G>C synonymous_variant 0.12
rpoA 3878391 c.117T>G synonymous_variant 0.14
rpoA 3878400 c.108T>C synonymous_variant 0.12
rpoA 3878493 c.15G>A synonymous_variant 1.0
ddn 3986987 c.144G>T synonymous_variant 1.0
ddn 3987180 p.Asp113Asn missense_variant 1.0
clpC1 4038812 c.1893T>C synonymous_variant 0.12
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.14
clpC1 4038860 c.1845G>T synonymous_variant 0.25
clpC1 4038878 c.1827A>G synonymous_variant 0.2
clpC1 4038989 c.1716T>C synonymous_variant 0.14
clpC1 4038997 c.1708T>C synonymous_variant 0.13
clpC1 4039031 c.1674T>C synonymous_variant 0.14
clpC1 4039064 c.1641C>T synonymous_variant 0.15
clpC1 4039070 c.1635G>C synonymous_variant 0.12
clpC1 4039136 c.1569C>T synonymous_variant 0.12
clpC1 4039142 c.1563A>G synonymous_variant 0.12
clpC1 4039145 c.1560G>C synonymous_variant 0.11
clpC1 4039166 c.1539G>A synonymous_variant 0.12
clpC1 4039169 c.1536A>G synonymous_variant 0.12
clpC1 4039172 c.1533A>G synonymous_variant 0.14
clpC1 4039178 c.1527G>C synonymous_variant 0.14
clpC1 4039183 c.1522T>C synonymous_variant 0.15
clpC1 4039190 c.1515C>T synonymous_variant 0.15
clpC1 4039196 c.1509G>A synonymous_variant 0.15
clpC1 4039199 p.Ala502Glu missense_variant 0.16
clpC1 4039208 c.1497C>G synonymous_variant 0.18
clpC1 4039220 c.1485G>C synonymous_variant 0.21
clpC1 4039238 c.1467C>T synonymous_variant 0.22
clpC1 4039265 c.1440C>T synonymous_variant 0.16
clpC1 4039274 c.1431G>C synonymous_variant 0.15
clpC1 4039277 c.1428C>G synonymous_variant 0.17
clpC1 4039280 c.1425G>T synonymous_variant 0.14
clpC1 4039283 c.1422C>T synonymous_variant 0.13
clpC1 4039286 c.1419T>G synonymous_variant 0.14
clpC1 4039292 c.1413C>T synonymous_variant 0.19
clpC1 4039316 p.Glu463Asp missense_variant 0.15
clpC1 4039319 c.1386T>A synonymous_variant 0.15
clpC1 4039322 c.1383T>G synonymous_variant 0.14
clpC1 4039360 p.Ser449Arg missense_variant 0.15
clpC1 4039361 c.1344C>G synonymous_variant 0.15
clpC1 4039397 c.1308A>G synonymous_variant 0.18
clpC1 4039409 c.1296T>C synonymous_variant 0.16
clpC1 4039412 c.1293T>G synonymous_variant 0.21
clpC1 4039415 p.Glu430Asp missense_variant 0.24
clpC1 4039430 c.1275T>C synonymous_variant 0.31
clpC1 4039442 c.1263A>G synonymous_variant 0.32
clpC1 4039451 c.1254G>A synonymous_variant 0.28
clpC1 4039454 c.1251A>T synonymous_variant 0.3
clpC1 4039457 c.1248C>T synonymous_variant 0.27
clpC1 4039463 c.1242C>G synonymous_variant 0.19
clpC1 4039466 c.1239T>C synonymous_variant 0.19
clpC1 4039469 c.1236T>C synonymous_variant 0.19
clpC1 4039472 c.1233G>C synonymous_variant 0.21
clpC1 4039478 c.1227G>C synonymous_variant 0.19
clpC1 4039481 c.1224T>C synonymous_variant 0.18
clpC1 4039484 c.1221T>A synonymous_variant 0.19
clpC1 4039487 c.1218G>C synonymous_variant 0.17
clpC1 4039556 c.1149G>C synonymous_variant 0.11
clpC1 4039562 c.1143C>G synonymous_variant 0.11
clpC1 4039565 c.1140G>C synonymous_variant 0.12
clpC1 4039574 p.Ala377Gly missense_variant 0.12
clpC1 4039577 c.1128T>C synonymous_variant 0.15
clpC1 4039586 c.1119G>C synonymous_variant 0.18
clpC1 4039589 c.1116G>C synonymous_variant 0.22
clpC1 4039610 c.1095G>T synonymous_variant 0.22
clpC1 4039616 c.1089G>C synonymous_variant 0.26
clpC1 4039622 c.1083C>T synonymous_variant 0.24
clpC1 4039649 c.1056G>C synonymous_variant 0.22
clpC1 4039652 c.1053G>C synonymous_variant 0.23
clpC1 4039682 c.1023C>G synonymous_variant 0.27
clpC1 4039694 c.1011G>C synonymous_variant 0.29
clpC1 4039724 c.981A>G synonymous_variant 0.26
clpC1 4039733 c.972G>C synonymous_variant 0.24
clpC1 4039739 c.966C>G synonymous_variant 0.24
clpC1 4039751 c.954A>G synonymous_variant 0.2
clpC1 4039757 c.948A>G synonymous_variant 0.18
clpC1 4039769 c.936C>T synonymous_variant 0.24
clpC1 4039775 c.930G>C synonymous_variant 0.23
clpC1 4039778 c.927A>G synonymous_variant 0.24
clpC1 4039793 c.912C>G synonymous_variant 0.21
clpC1 4039805 c.900C>T synonymous_variant 0.19
clpC1 4039814 c.891C>G synonymous_variant 0.18
clpC1 4039817 c.888A>C synonymous_variant 0.18
clpC1 4039820 c.885T>G synonymous_variant 0.18
clpC1 4039831 c.874T>C synonymous_variant 0.16
clpC1 4039844 c.861C>T synonymous_variant 0.12
clpC1 4039850 c.855T>C synonymous_variant 0.12
clpC1 4039931 c.774T>C synonymous_variant 0.12
clpC1 4039934 c.771G>C synonymous_variant 0.11
clpC1 4039943 c.762G>C synonymous_variant 0.12
clpC1 4039946 c.759A>G synonymous_variant 0.12
clpC1 4039949 c.756G>C synonymous_variant 0.12
clpC1 4039952 c.753T>C synonymous_variant 0.19
clpC1 4039958 c.747G>C synonymous_variant 0.22
clpC1 4039964 c.741C>G synonymous_variant 0.24
clpC1 4039975 p.Asp244Asn missense_variant 0.21
clpC1 4039979 c.726C>G synonymous_variant 0.19
clpC1 4039982 c.723G>A synonymous_variant 0.16
clpC1 4040000 c.705C>T synonymous_variant 0.15
clpC1 4040021 c.684A>C synonymous_variant 0.22
clpC1 4040024 c.681A>G synonymous_variant 0.23
clpC1 4040033 c.672G>C synonymous_variant 0.29
clpC1 4040042 c.663C>T synonymous_variant 0.22
clpC1 4040057 c.648C>T synonymous_variant 0.15
clpC1 4040090 p.Ser205Cys missense_variant 0.11
clpC1 4040093 c.612C>G synonymous_variant 0.12
clpC1 4040824 c.-120C>T upstream_gene_variant 1.0
embC 4239843 c.-20A>C upstream_gene_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4242425 p.Arg855Gly missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embA 4244635 p.Val468Ala missense_variant 1.0
embA 4245147 p.Pro639Ser missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethR 4326928 c.-621G>A upstream_gene_variant 1.0
ethA 4327103 p.Gly124Asp missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0